J. DeVoss

发表

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination

P. Fontoura, H. Garren, R. Pedotti, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Image Analysis-Based Approaches for Scoring Mouse Models of Colitis

J. DeVoss, R. Rogers, J. Eastham‐Anderson, 2016, Veterinary pathology.

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.

Adam R. Johnson, Jun Liang, J. DeVoss, 2013, Journal of medicinal chemistry.

Effector Mechanisms of the Autoimmune Syndrome in the Murine Model of Autoimmune Polyglandular Syndrome Type 11

Mark S. Anderson, J. DeVoss, A. Shum, 2008, The Journal of Immunology.

Actin-Bundling Protein L-Plastin Regulates T Cell Activation

D. Danilenko, J. DeVoss, P. Allen, 2010, The Journal of Immunology.

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury

N. van Bruggen, M. Hedehus, J. DeVoss, 2016, Cell Death and Differentiation.

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Jinfeng Liu, Saritha Kusam, Jeffrey Tom, 2015, Nature.

An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides

Cleopatra Kozlowski, Xiaoting Wang, J. DeVoss, 2013, Disease Models & Mechanisms.

Rate of cognitive decline in AD is accelerated by the interleukin-1α −889 *1 allele

J. Yesavage, J. Tinklenberg, J. DeVoss, 2001, Neurology.

A novel myelin P0–specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy

Mark S. Anderson, J. Bluestone, J. DeVoss, 2009, The Journal of experimental medicine.

Immunomodulation of Experimental Autoimmune Encephalomyelitis with Ordered Peptides Based on MHC-TCR Binding Motifs1

K. Garcia, P. Fontoura, J. DeVoss, 2001, The Journal of Immunology.

Autoimmune Polyglandular Syndrome Type Syndrome in the Murine Model of Effector Mechanisms of the Autoimmune

Norbert, J. DeVoss, A. Shum, 2008 .

Lessons on immune tolerance from the monogenic disease APS1.

Mark S. Anderson, J. DeVoss, 2007, Current opinion in genetics & development.

Listeria monocytogenes personalized cancer vaccines drive therapeutic immune responses to cancer derived neoantigens

J. Johnston, J. DeVoss, J. Lesch, 2020, bioRxiv.

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

Howard Y. Chang, Mark S. Anderson, D. Wong, 2008, Science.

Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment

J. Egen, J. DeVoss, Brian Belmontes, 2021, Cancer Immunology, Immunotherapy.

CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis

M. Yaylaoglu, H. Collard, J. Egen, 2017, Thorax.

Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell–cold solid tumors

Deepali V. Sawant, J. Egen, J. DeVoss, 2021, Science Translational Medicine.

An aberrant prostate antigen-specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans.

Mark S. Anderson, D. McNeel, J. DeVoss, 2009, The Journal of clinical investigation.

This information is current as-Deficient Mouse Aire Eye in the Binding Protein 1 a Is Associated with Dry An Autoimmune Response to Odorant

J. DeVoss, L. Fong, Kellsey P. A. Johannes, 2010 .

An Autoimmune Response to Odorant Binding Protein 1a Is Associated with Dry Eye in the Aire-Deficient Mouse

Mark S. Anderson, J. DeVoss, N. Grewal, 2010, The Journal of Immunology.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2017, JCI insight.

An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.

J. DeVoss, T. Pham, Cécile Chalouni, 2015, Molecular pharmaceutics.

Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease.

Mark S. Anderson, J. DeVoss, Shimin Li, 2008, Investigative ophthalmology & visual science.

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

J. DeVoss, S. Warming, Tianbo Li, 2017, Nature Communications.

Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus

H. Mcdevitt, R. Pedotti, J. DeVoss, 2003, BMC Immunology.

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

D. Danilenko, J. DeVoss, A. Zarrin, 2019, Front. Immunol..

Cellular Control of Autoimmunity in the Aire-Deficient Mouse Model of Sjogren’s Syndrome

Mark S. Anderson, J. DeVoss, C. Meagher, 2008 .

Peptides Based on MHC-TCR Binding Motifs OrderedAutoimmune Encephalomyelitis with Immunomodulation of Experimental

K. Garcia, P. Fontoura, J. DeVoss, 2001 .

Defective Aire-Dependent Central Tolerance to P0 Is Linked to Autoimmune Peripheral Neuropathy

Mark S. Anderson, Antonella, J. DeVoss, 2013 .

Defective Autoimmune Regulator-Dependent Central Tolerance to Myelin Protein Zero Is Linked to Autoimmune Peripheral Neuropathy

Mark S. Anderson, J. DeVoss, A. Meloni, 2012, The Journal of Immunology.

NeuropathyLinked to Autoimmune Peripheral Central Tolerance to Myelin Protein Zero Is Defective Autoimmune Regulator-Dependent

Mark S. Anderson, J. DeVoss, A. Meloni, 2012 .

Critical role of activation induced cytidine deaminase in Experimental Autoimmune Encephalomyelitis

J. DeVoss, A. Zarrin, S. Warming, 2012, Autoimmunity.

Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X

J. DeVoss, V. Dixit, Jinfeng Liu, 2014, The Journal of experimental medicine.

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.

Adam R. Johnson, Jun Liang, J. DeVoss, 2017, Bioorganic & medicinal chemistry letters.

Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.

P. McEwan, J. DeVoss, A. Zarrin, 2015, Journal of medicinal chemistry.

Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.

Adam R. Johnson, P. Lockey, W. Ouyang, 2015, Journal of medicinal chemistry.

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

Aly A. Khan, J. DeVoss, I. Mellman, 2013, Nature Immunology.

Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.

Howard Y. Chang, Mark S. Anderson, J. Rinn, 2008, The Journal of clinical investigation.

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

J. DeVoss, R. Graham, L. Diehl, 2014, Nature.

Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response

J. DeVoss, A. Zarrin, Lawren C. Wu, 2015, Science Signaling.

Murine Models of Inflammatory Bowel Disease (IBD)

J. DeVoss, L. Diehl, 2014, Toxicologic pathology.

Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection

Mark S. Anderson, J. Sidney, A. Sette, 2012, Proceedings of the National Academy of Sciences.

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.

Melinda M. Mulvihill, J. DeVoss, W. Fairbrother, 2018, Molecular cell.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2018, Nature Communications.

The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation

Z. Modrušan, J. DeVoss, A. Zarrin, 2017, Science Signaling.

NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.

M. Westphall, J. DeVoss, A. Attie, 2016, Cell reports.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Adam R. Johnson, Z. Modrušan, J. DeVoss, 2018, Nature Communications.

PILRα Negatively Regulates Mouse Inflammatory Arthritis

S. Kummerfeld, W. Ouyang, J. DeVoss, 2014, The Journal of Immunology.

STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets

Deepali V. Sawant, W. Ouyang, J. DeVoss, 2021, The Journal of experimental medicine.

Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies

M. Brug, T. Beach, J. DeVoss, 2015, Neuron.

Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2.

Jane R Kenny, Philippe Bergeron, Ignacio Aliagas, 2013, Journal of medicinal chemistry.

Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2.

Jane R Kenny, Philippe Bergeron, Tian Jin, 2012, Journal of medicinal chemistry.

Spontaneous autoimmunity prevented by thymic expression of a single self-antigen

Mark S. Anderson, J. Rinn, J. DeVoss, 2006, The Journal of experimental medicine.

Identification of an Autoantigen Demonstrates a Link Between Interstitial Lung Disease and a Defect in Central Tolerance

Mark S. Anderson, J. DeVoss, K. Jones, 2009, Science Translational Medicine.

Generation of bone marrow chimeras using X-ray irradiation: comparison to cesium irradiation and use in immunotherapy

Deepali V. Sawant, J. DeVoss, J. Eng, 2020, Journal of biological methods.

Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

J. DeVoss, D. Seshasayee, W. Sandoval, 2016, Nature.

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes

Thijs J. Hagenbeek, Steve Lianoglou, S. Rutz, 2018, Science Immunology.

Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation

Aly A. Khan, M. Weirauch, J. DeVoss, 2017, The Journal of cell biology.

Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity

J. DeVoss, K. Ali, S. Casey, 2020, Frontiers in Immunology.

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

S. Rutz, P. Valdez, Z. Modrušan, 2014, Nature.

Mouse Models of Rheumatoid Arthritis

J. DeVoss, L. Diehl, P. Caplazi, 2015, Veterinary pathology.

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells

S. Rutz, Z. Modrušan, W. Ouyang, 2014, Nature.

OncoVEXmGM-CSFexpands tumor antigen-specific CD8+ T-cell response in preclinical models

J. DeVoss, J. Werner, J. Estrada, 2023, Journal for ImmunoTherapy of Cancer.

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1

Meijuan Zhou, Min Xu, Zora Modrusan, 2013, Nature Immunology.

Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity

J. Egen, J. DeVoss, S. Novitskiy, 2022, Cancer Immunology, Immunotherapy.

Analysis of neuronal gene expression with laser capture microdissection

J. DeVoss, H. Ryan, G. Murphy, 2002, Journal of neuroscience research.

Autonomous IL-36R signaling in neutrophils activates potent antitumor effector functions

J. Egen, J. DeVoss, C. Tinberg, 2023, The Journal of clinical investigation.

A Suppressive Oligodeoxynucleotide Enhances the Efficacy of Myelin Cocktail/IL-4-Tolerizing DNA Vaccination and Treats Autoimmune Disease1

Michael Platten, Brian A. Kidd, Lawrence Steinman, 2005, The Journal of Immunology.

Immunity to the Extracellular Domain of Nogo-A Modulates Experimental Autoimmune Encephalomyelitis1

P. Fontoura, W. Robinson, M. Tessier-Lavigne, 2004, The Journal of Immunology.

Autoimmune Encephalomyelitis Nogo-A Modulates Experimental Immunity to the Extracellular Domain of Lawrence

P. Fontoura, W. Robinson, M. Tessier-Lavigne, 2004 .

A novel quantitative trait locus on mouse chromosome 18, "era1," modifies the entrainment of circadian rhythms.

J. DeVoss, B. O’Hara, D. Edgar, 2007, Sleep.

PILRα Negatively Regulates Mouse Inflammatory Arthritis

S. Kummerfeld, W. Ouyang, J. DeVoss, 2014, The Journal of Immunology.