Hyun-Dong Chang

发表

Particle robotics based on statistical mechanics of loosely coupled components

Daniela Rus, Hod Lipson, Shuguang Li, 2019, Nature.

Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory

Z. Fang, M. Raftery, Hyun-Dong Chang, 2014, Proceedings of the National Academy of Sciences.

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

Na Li, Andreas Thiel, Andreas Bosio, 2010, Nature Immunology.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

J. Paul Robinson, Jonathan A. Rebhahn, Kylie M. Quinn, 2019, European journal of immunology.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

J. Paul Robinson, Jonathan A. Rebhahn, B. Becher, 2017, European journal of immunology.

Demethylation of the RORC2 and IL17A in Human CD4+ T Lymphocytes Defines Th17 Origin of Nonclassic Th1 Cells

Hyun-Dong Chang, Andreas Radbruch, A. Thiel, 2015, The Journal of Immunology.

Epigenetic Control of the foxp3 Locus in Regulatory T Cells

Edgar Schmitt, Sven Olek, Hyun-Dong Chang, 2007, PLoS biology.

Cyt‐Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops

S. Müller, Lili Wang, R. Brinkman, 2019, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

A Ca2+ concentration of 1.5 mM, as present in IMDM but not in RPMI, is critical for maximal response of Th cells to PMA/ionomycin

Hyun-Dong Chang, Andreas Radbruch, J. Zimmermann, 2015, European journal of immunology.

Antigen-driven PD-1+TOX+EOMES+ and PD-1+TOX+BHLHE40+ synovial T lymphocytes regulate chronic inflammation in situ

Hyun-Dong Chang, R. Riedel, F. Annunziato, 2019, bioRxiv.

Autocrine IL‐10 promotes human B‐cell differentiation into IgM‐ or IgG‐secreting plasmablasts

Hyun-Dong Chang, Andreas Radbruch, J. Grün, 2014, European journal of immunology.

Resident memory CD4+ T lymphocytes mobilize from bone marrow to contribute to a systemic secondary immune reaction

Hyun-Dong Chang, H. Volk, Simon Reinke, 2022, European journal of immunology.

Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice.

M. Jordana, Hyun-Dong Chang, N. Van Rooijen, 2011, The Journal of allergy and clinical immunology.

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

V. Greiff, Hyun-Dong Chang, S. Reddy, 2020, Nature Communications.

Pathogenic memory plasma cells in autoimmunity

Hyun-Dong Chang, K. Tokoyoda, G. Burmester, 2019, Current opinion in immunology.

Quantifying Antigen-Specific T-Cells by Assessing Their Antigen-Induced Proliferation.

Hyun-Dong Chang, Aa Shah, 2021, Methods in molecular biology.

Targeting pathogenic T helper cell memory

Hyun-Dong Chang, A. Radbruch, 2011, Annals of the rheumatic diseases.

Mobilization of tissue-resident memory CD4+ T lymphocytes and their contribution to a systemic secondary immune reaction

Hyun-Dong Chang, H. Volk, Jun Dong, 2020, bioRxiv.

Epigenetic Imprinting of Immunological Memory

Hyun-Dong Chang, Jun Dong, Andreas Dr Radbruch, 2016 .

Loss of methylation at the IFNG promoter and CNS‐1 is associated with the development of functional IFN‐γ memory in human CD4+ T lymphocytes

M. Gossen, Hyun-Dong Chang, Andreas Radbruch, 2013, European journal of immunology.

Static and dynamic components synergize to form a stable survival niche for bone marrow plasma cells

Hyun-Dong Chang, Andreas Radbruch, R. Niesner, 2014, European journal of immunology.

Stromal cell-contact dependent PI3K and APRIL induced NF-κB signaling complement each other to prevent mitochondrial- and endoplasmic reticulum stress induced cell death of bone marrow plasma cells

Hyun-Dong Chang, K. Tokoyoda, P. Durek, 2019, bioRxiv.

Regulation of Fatty Acid Oxidation by Twist 1 in the Metabolic Adaptation of T Helper Lymphocytes to Chronic Inflammation

K. Minden, Hyun-Dong Chang, J. Grün, 2019, Arthritis & Rheumatology (Hoboken, N.j.).

MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes

Hyun-Dong Chang, Andreas Radbruch, K. Westendorf, 2018, Front. Immunol..

Mass cytometry‐based identification of a unique T‐cell signature in childhood allergic asthma

Hyun-Dong Chang, M. Huber, H. Raifer, 2021, Allergy. European Journal of Allergy and Clinical Immunology.

Nitric oxide enhances Th9 cell differentiation and airway inflammation

B. Ryffel, Hyun-Dong Chang, F. Liew, 2014, Nature Communications.

Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma

L. Bullinger, Hyun-Dong Chang, R. Jenq, 2022, Gut microbes.

Keeping up with the stress of antibody production: BAFF and APRIL maintain memory plasma cells.

Hyun-Dong Chang, Andreas Radbruch, Rebecca Cornelis, 2021, Current opinion in immunology.

Plasma cell differentiation in T‐independent type 2 immune responses is independent of CD11chigh dendritic cells

Steffen Jung, Hyun-Dong Chang, Andreas Radbruch, 2006, European journal of immunology.

Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice

Hyun-Dong Chang, E. Douni, T. Kamradt, 2015, Arthritis Research & Therapy.

Deep phenotypical characterization of human CD3+CD56+ T cells by mass cytometry

Hyun-Dong Chang, M. Huber, M. Lohoff, 2020, European journal of immunology.

A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4+ T lymphocytes in unexposed individuals

Hyun-Dong Chang, Andreas Radbruch, Jun Dong, 2022, Frontiers in Immunology.

The Pro‐ and Anti‐Inflammatory Potential of Interleukin‐12

Hyun-Dong Chang, Andreas Radbruch, 2007, Annals of the New York Academy of Sciences.

Specific microbiota enhances intestinal IgA levels by inducing TGF‐β in T follicular helper cells of Peyer's patches in mice

Hyun-Dong Chang, R. Riedel, P. Durek, 2020, European journal of immunology.

A long-term perspective on immunity to COVID

Hyun-Dong Chang, Andreas Dr Radbruch, 2021, Nature.

Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells

Hyun-Dong Chang, Andreas Radbruch, K. Thurley, 2022, Cells.

Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2Chi Natural Killer Cells

J. Walter, Hyun-Dong Chang, Jun Dong, 2014, PLoS pathogens.

1,25‐dihydroxyvitamin D3 promotes IL‐10 production in human B cells

Andreas Radbruch, Guido Heine, Andreas Steinmeyer, 2008, European journal of immunology.

Nuclear Factor of Activated T Cells Regulates the Expression of Interleukin-4 in Th2 Cells in an All-or-none Fashion

Hyun-Dong Chang, Andreas Radbruch, R. Riedel, 2014, The Journal of Biological Chemistry.

IMprinting of PAthogenic Memory in Berlin

Hyun-Dong Chang, A. Hauser, C. Romagnani, 2013, European journal of immunology.

NK cells gain higher IFN‐γ competence during terminal differentiation

Hyun-Dong Chang, A. Thiel, Jun Dong, 2014, European journal of immunology.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Amit A. Patel, F. Ginhoux, D. Busch, 2021, European journal of immunology.

IL-1β and TGF-β Act Antagonistically in Induction and Differentially in Propagation of Human Proinflammatory Precursor CD4+ T Cells

Hyun-Dong Chang, K. Hebel, M. Brunner‐Weinzierl, 2011, The Journal of Immunology.

Immunological memories of the bone marrow

Hyun-Dong Chang, Andreas Radbruch, K. Tokoyoda, 2018, Immunological reviews.

IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts

A. Waisman, Hyun-Dong Chang, R. Savai, 2023, Gut.

Memory CD8+ T cells colocalize with IL-7+ stromal cells in bone marrow and rest in terms of proliferation and transcription

Hyun-Dong Chang, Andreas Radbruch, R. Riedel, 2015, European journal of immunology.

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

W. Shi, Yang Liao, S. Rutz, 2019, Nature Immunology.

Lymphocyte signaling: regulation of FoxO transcription factors by microRNAs

Hyun-Dong Chang, Andreas Radbruch, C. Haftmann, 2012, Annals of the New York Academy of Sciences.

Maintenance of quiescent immune memory in the bone marrow

Hyun-Dong Chang, A. Radbruch, 2021, European journal of immunology.

Th memory for interleukin‐17 expression is stable in vivo

Hyun-Dong Chang, Andreas Radbruch, Maria H. Lexberg, 2008, European journal of immunology.

Rethinking ‘immunological memory’: Local and systemic immunity provided by bone marrow‐resident memory cells

Hyun-Dong Chang, Jun Dong, M. Mashreghi, 2022, Scandinavian Journal of Immunology.

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

W. Shi, Yang Liao, S. Rutz, 2019, Nature Immunology.

Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature

Hyun-Dong Chang, G. Duda, K. Schmidt-Bleek, 2017, Nature Communications.

Differential Expression of miR‐4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF)

Hyun-Dong Chang, D. Kardassis, J. Grün, 2016, Journal of cellular physiology.

T-bet and RORα control lymph node formation by regulating embryonic innate lymphoid cell differentiation

Hyun-Dong Chang, P. Durek, M. Mashreghi, 2021, Nature Immunology.

The intestinal microbiota determines the colitis‐inducing potential of T‐bet‐deficient Th cells in mice

S. Müller, Hyun-Dong Chang, Andreas Radbruch, 2017, European journal of immunology.

Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT

B. Sharrack, Hyun-Dong Chang, M. Mohty, 2021, Frontiers in Oncology.

Authentic IgM Fc Receptor (FcμR).

Hyun-Dong Chang, P. Durek, A. Radbruch, 2017, Current topics in microbiology and immunology.

Direct uptake of Antagomirs and efficient knockdown of miRNA in primary B and T lymphocytes

Hyun-Dong Chang, R. Riedel, C. Haftmann, 2015, Journal of immunological methods.

IL‐10‐producing B cells are characterized by a specific methylation signature

E. Dalla, M. Colombo, Hyun-Dong Chang, 2019, European journal of immunology.

A Critical Control Element for Interleukin-4 Memory Expression in T Helper Lymphocytes*

Andreas Radbruch, Hyun-Dong Chang, W. Paul, 2005, Journal of Biological Chemistry.

High‐resolution microbiota flow cytometry reveals dynamic colitis‐associated changes in fecal bacterial composition

T. Hübschmann, S. Müller, Hyun-Dong Chang, 2016, European journal of immunology.

Eomes controls the development of Th17‐derived (non‐classic) Th1 cells during chronic inflammation

Hyun-Dong Chang, L. Cosmi, F. Annunziato, 2018, European journal of immunology.

Antigen‐driven PD‐1+TOX+BHLHE40+ and PD‐1+TOX+EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ

Hyun-Dong Chang, R. Riedel, F. Annunziato, 2020, European journal of immunology.

The pro- and anti-inflammatory potential of IL-12: the dual role of Th1 cells

Hyun-Dong Chang, Andreas Radbruch, 2007, Expert review of clinical immunology.

Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.

Ho-Ryun Chung, Thomas Lengauer, Florian Schmidt, 2016, Immunity.

Autoregulation of Th1-mediated inflammation by twist1

C. Loddenkemper, S. Rutz, A. Scheffold, 2008, The Journal of experimental medicine.

Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow

Hyun-Dong Chang, Andreas Radbruch, K. Tokoyoda, 2018, Proceedings of the National Academy of Sciences.

Diversity and flexibility of Th17 effector functions

Hyun-Dong Chang, T. Kamradt, 2011, Arthritis research & therapy.

MicroRNA-182 is induced by IL-2 and promotes clonal expansion of 1 activated helper T lymphocytes 2

Thomas, Christoph, Wei, 2019 .

IL-1b and TGF-b Act Antagonistically in Induction and Differentially in Propagation of Human Proinflammatory Precursor CD4 T Cells

Hyun-Dong Chang, K. Hebel, M. Rudolph, 2011 .

current as T Cells + of Human Proinflammatory Precursor CD 4 Induction and Differentially in Propagation Act Antagonistically in β and TGF-β IL-1 Brunner-Weinzierl

Hyun-Dong Chang, K. Hebel, M. Brunner‐Weinzierl, 2011 .

Expression of IL‐10 in Th memory lymphocytes is conditional on IL‐12 or IL‐4, unless the IL‐10 gene is imprinted by GATA‐3

Hyun-Dong Chang, Andreas Radbruch, C. Helbig, 2007, European journal of immunology.

IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells

Hyun-Dong Chang, Andreas Radbruch, R. Riedel, 2014, Science Translational Medicine.

Persistence of effector memory Th1 cells is regulated by Hopx

J. Epstein, C. Loddenkemper, Hyun-Dong Chang, 2010, European journal of immunology.

Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells

Hyun-Dong Chang, K. Tokoyoda, P. Durek, 2020, Cell reports.

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

V. Greiff, Hyun-Dong Chang, S. Reddy, 2019, bioRxiv.

Leptin: a critical regulator of CD4+ T-cell polarization in vitro and in vivo.

Hyun-Dong Chang, M. Zeitz, R. Glauben, 2010, Endocrinology.

Innate-Like Effector Differentiation of Human Invariant NKT Cells Driven by IL-71

Hyun-Dong Chang, Andreas Radbruch, G. Borsellino, 2008, The Journal of Immunology.

Human Invariant NKT Cells Driven by IL-7 Innate-Like Effector Differentiation of Casorati Aiuti

Hyun-Dong Chang, Andreas Radbruch, G. Borsellino, 2008 .

IL-10 Is Excluded from the Functional Cytokine Memory of Human CD4+ Memory T Lymphocytes1

Hyun-Dong Chang, Andreas Radbruch, A. Thiel, 2007, The Journal of Immunology.

Mathematical modeling reveals a complex network of signaling and apoptosis pathways in the survival of memory plasma cells

Hyun-Dong Chang, Andreas Radbruch, K. Thurley, 2021, bioRxiv.

Immunological memory in rheumatic inflammation — a roadblock to tolerance induction

Hyun-Dong Chang, M. Mashreghi, A. Radbruch, 2021, Nature Reviews Rheumatology.

IFN‐γ and IL‐12 synergize to convert in vivo generated Th17 into Th1/Th17 cells

Andreas Radbruch, Hyun-Dong Chang, Thomas Kamradt, 2010, European journal of immunology.

SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself

M. Raftery, Hyun-Dong Chang, T. Winkler, 2021, Nature Communications.

In severe COVID-19, SARS-CoV-2 induces a chronic, TGF-Î²-dominated adaptive immune response

Hyun-Dong Chang, T. Winkler, H. Volk, 2020, medRxiv.

Induction of cross-reactive antibody responses against the RBD domain of the spike protein of SARS-CoV-2 by commensal microbiota

Hyun-Dong Chang, Andreas Radbruch, G. Schönrich, 2021, bioRxiv.

Cell population identification using fluorescence-minus-one controls with a one-class classifying algorithm

Andreas Radbruch, Hyun-Dong Chang, Jenny Kirsch, 2014, Bioinform..

Particle robotics based on statistical mechanics of loosely coupled components

Hod Lipson, D. Rus, Shuguang Li, 2019, Nature.

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim

N. Rajewsky, Z. Fang, Wei Chen, 2015, European journal of immunology.

Selection and depletion of plasma cells based on the specificity of the secreted antibody

Hyun-Dong Chang, A. Thiel, A. Radbruch, 2015, European journal of immunology.

Unbiased transcriptomes of resting human CD4+CD45RO+ T lymphocytes

Hyun-Dong Chang, Andreas Radbruch, Anna Okhrimenko, 2014, European journal of immunology.

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo

N. Rajewsky, Hyun-Dong Chang, Andreas Radbruch, 2017, Journal of autoimmunity.

CD69+ memory T lymphocytes of the bone marrow and spleen express the signature transcripts of tissue‐resident memory T lymphocytes

Hyun-Dong Chang, Andreas Radbruch, Jun Dong, 2018, European journal of immunology.

Maintenance of CD8+ memory T lymphocytes in the spleen but not in the bone marrow is dependent on proliferation

Hyun-Dong Chang, Andreas Radbruch, K. Tokoyoda, 2017, European journal of immunology.

Organization and maintenance of immunological memory by stroma niches

Hyun-Dong Chang, Andreas Radbruch, K. Tokoyoda, 2009, European journal of immunology.

Traditional Grain-Based vs. Commercial Milk Kefirs, How Different Are They?

P. Neubauer, S. Junne, Hyun-Dong Chang, 2022, Applied Sciences.

Rapid detection and online analysis of microbial changes through flow cytometry

K. Ickstadt, Hyun-Dong Chang, C. Esser, 2022, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

A7.19 Systemic inhibition of MIR-148A by antagomirs reduces CD4+ T helper cell numbers and alleviates inflammation in a preclinical model of transfer colitis

Hyun-Dong Chang, Andreas Radbruch, R. Riedel, 2016 .

Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature

Hyun-Dong Chang, G. Duda, K. Schmidt-Bleek, 2017, Nature Communications.

Single‐cell transcriptomes of murine bone marrow stromal cells reveal niche‐associated heterogeneity

Hyun-Dong Chang, Andreas Radbruch, P. Durek, 2019, European journal of immunology.

Beyond sequencing: fast and easy microbiome profiling by flow cytometry

Hyun-Dong Chang, C. Esser, J. Krutmann, 2019, Archives of Toxicology.