S. Hanks

发表

Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members.

S. Hanks, A. M. Quinn, 1991, Methods in enzymology.

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.

T. Hunter, S. Hanks, A. M. Quinn, 1988, Science.

Cellular responses to substrate topography: role of myosin II and focal adhesion kinase.

S. Hanks, Yu-Li Wang, T. Russell, 2006, Biophysical journal.

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

S. Hanks, M. Calalb, T. Polte, 1995, Molecular and cellular biology.

Chromatin structure during the prereplicative phases in the life cycle of mammalian cells

S. Hanks, P. N. Rao, P. Rao, 1980, Cell Biophysics.

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

T. Hunter, S. Hanks, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

T. Hunter, S. Hanks, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas.

S. Hanks, T. Polte, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms of CAS Substrate Domain Tyrosine Phosphorylation by FAK and Src

S. Hanks, N. Shin, T. Polte, 2001, Molecular and Cellular Biology.

Dynamics and Mechanism of p130Cas Localization to Focal Adhesions*

S. Hanks, I. Kaverina, D. Donato, 2010, The Journal of Biological Chemistry.

Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness

S. Hanks, D. Rösel, J. Brábek, 2011, Molecular biology of the cell.

Structures Inherent to Chromatin Active in Transcription and Replication

S. Hanks, A. Annunziato, R. Seale, 1984 .

Complexes of Focal Adhesion Kinase (FAK) and Crk-associated Substrate (p130Cas) Are Elevated in Cytoskeleton-associated Fractions following Adhesion and Src Transformation

S. Hanks, T. Polte, 1997, The Journal of Biological Chemistry.

Phosphorylation of E2F-1 by cyclin A-cdk2.

M. Kitagawa, S. Hanks, Y. Taya, 1995, Oncogene.

Focal Adhesion Kinase Suppresses Apoptosis by Binding to the Death Domain of Receptor-Interacting Protein

S. Hanks, Zheng‐gang Liu, W. Cance, 2004, Molecular and Cellular Biology.

Cell cycle-specific changes in the ultrastructural organization of prematurely condensed chromosomes

S. Hanks, W. Hittelman, S. Gollin, 1983, Chromosoma.

The tubulogenic activity associated with an activated form of Flt-1 kinase is dependent on focal adhesion kinase.

S. Hanks, M. Shibuya, Y. Maru, 2001, Biochimica et biophysica acta.

Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

S. Hanks, Q. Ding, C. Gladson, 2004, Oncogene.

A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly.

Andrés J. García, S. Hanks, I. Kaverina, 2008, Cell motility and the cytoskeleton.

The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling.

S. Hanks, W. Song, N. Shin, 2008, Molecular biology of the cell.

ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility

S. Hanks, Weifeng Luo, J. Brábek, 2017, Journal of Cell Science.

Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis.

S. Hanks, D. Schlaepfer, D. Cheresh, 2009, Cancer research.

KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1.

K. Gould, S. Hanks, Matthew R Broadus, 2011, Experimental cell research.

Absolute quantification of phosphorylation on the kinase activation loop of cellular focal adhesion kinase by stable isotope dilution liquid chromatography/mass spectrometry.

S. Hanks, Eugene Ciccimaro, I. Blair, 2009, Analytical chemistry.

Crk-Associated Substrate Tyrosine Phosphorylation Sites Are Critical for Invasion and Metastasis of Src-Transformed Cells

Sábata S Constancio, A. Pozzi, S. Hanks, 2005, Molecular Cancer Research.

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

S. Hanks, M. Calalb, M. Harper, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Dissociation of FAK/p130CAS/c-Src Complex during Mitosis: Role of Mitosis-specific Serine Phosphorylation of FAK

S. Hanks, F. Matsumura, G. Totsukawa, 1999, The Journal of cell biology.

Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.

T. Pawson, B. Mayer, S. Hanks, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II

S. Hanks, T. Polte, A. Naftilan, 1994, Journal of cellular biochemistry.

P130Cas Src-Binding and Substrate Domains Have Distinct Roles in Sustaining Focal Adhesion Disassembly and Promoting Cell Migration

D. Gochberg, S. Hanks, I. Kaverina, 2010, PloS one.

Focal Adhesion Kinase Is Activated and Mediates the Early Hypertrophic Response to Stretch in Cardiac Myocytes

Sábata S Constancio, S. Hanks, K. Franchini, 2003, Circulation research.

Regulation of FAK Ser-722 phosphorylation and kinase activity by GSK3 and PP1 during cell spreading and migration.

S. Hanks, E. Villa-Moruzzi, D. Turner, 2005, The Biochemical journal.

Phosphatidylinositol 5-phosphate 4-kinase

F. Tamanoi, K. Jacobson, Mark A Sussman, 2012 .

CAS promotes invasiveness of Src-transformed cells

Alissa M. Weaver, Sábata S Constancio, A. Pozzi, 2004, Oncogene.

Amino acid sequence of the BSC-1 cell growth inhibitor (polyergin) deduced from the nucleotide sequence of the cDNA.

S. Hanks, J. Spiess, F. Maldonado, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Anti-apoptotic Role of Focal Adhesion Kinase (FAK)

S. Hanks, D. Yamamoto, T. Kasahara, 2000, The Journal of Biological Chemistry.

Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.

T. Curran, S. Hanks, D. Salant, 2012, The Journal of clinical investigation.

Quantification of Focal Adhesion Kinase Activation Loop Phosphorylation as a Biomarker of Src Activity

S. Hanks, Eugene Ciccimaro, I. Blair, 2009, Molecular Pharmacology.

Molecular cloning of plant transcripts encoding protein kinase homologs.

C. Lamb, S. Hanks, R. Yamamoto, 1989, Proceedings of the National Academy of Sciences of the United States of America.

p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells.

S. Hanks, Anna C Cunningham-Edmondson, 2009, Breast cancer.

Receptor-Interacting Protein by Binding to the Death Domain of Focal Adhesion Kinase Suppresses Apoptosis

S. Hanks, W. Cance, A. Baldwin, 2004 .

Kinases/Phosphatases | FAK Family

S. Hanks, Sarah C. Stainbrook, 2021, Encyclopedia of Biological Chemistry III.

Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture.

S. Hanks, L. Nanney, L. King, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v‐Src, but is not a critical determinant of v‐Src transformation

S. Hanks, P. Ruest, Shyamali Roy, 2002, Journal of cellular biochemistry.

Phosphospecific antibodies reveal focal adhesion kinase activation loop phosphorylation in nascent and mature focal adhesions and requirement for the autophosphorylation site.

S. Hanks, R. Mernaugh, P. Ruest, 2000, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase–mediated tyrosine phosphorylation

S. Hanks, B. Wadzinski, B. Spiller, 2022, The Journal of biological chemistry.

THE ROLE OF THE TRANSACTIVATION DOMAIN IN C-MYC MEDIATED CELL CYCLE PROGRESSION AND TRANSFORMATION

David N. Boone, S. Hanks, S. Hiebert, 2008 .

Early initiation of DNA synthesis in G1 phase HeLa cells following fusion with red cell ghosts loaded with S-phase cell extracts.

S. Hanks, D. B. Brown, E. Murphy, 1985, Experimental cell research.

Initiation of DNA synthesis in the prematurely condensed chromosomes of G1 cells

S. Hanks, P. Rao, 1980, The Journal of cell biology.

Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells.

R. Coffey, S. Hanks, P. Dempsey, 2000, Experimental cell research.

Anti-apoptotic Role of Focal Adhesion Kinase (FAK): Induction of Inhibitor-of-Apoptosis Proteins and Apoptosis Suppression by the Overexpression of FAK in a Human Leukemic Cell Line, HL-60

S. Hanks, D. Yamamoto, T. Kasahara, 2000 .

A cDNA clone encoding human cAMP-dependent protein kinase catalytic subunit C alpha.

S. Hanks, F. Maldonado, Steven K. Hanks, 1988, Nucleic acids research.

Use of degenerate oligonucleotide probes to identify clones that encode protein kinases.

S. Hanks, R. Lindberg, 1991, Methods in enzymology.

Fak: Focal adhesion kinase (vertebrates) (FadK, pp125FAK)

S. Hanks, 1995 .

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

T. Hunter, S. Hanks, D. Schlaepfer, 1994, Nature.

Molecular cloning and enzymatic analysis of the rat homolog of "PhK-gamma T," an isoform of phosphorylase kinase catalytic subunit.

S. Hanks, M. Calalb, D. T. Fox, 1992, The Journal of biological chemistry.

Messenger ribonucleic acid encoding an apparent isoform of phosphorylase kinase catalytic subunit is abundant in the adult testis.

S. Hanks, 1989, Molecular endocrinology.

c-Jun is essential for organization of the epidermal leading edge.

J. Arbeit, S. Hanks, K. Pogliano, 2003, Developmental cell.

Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility.

S. Hanks, N. Shin, J. Brábek, 2003, Frontiers in bioscience : a journal and virtual library.

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

Micah Dembo, Steven K. Hanks, M. Dembo, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

Steven K. Hanks, Charles J. Sherr, Martine F. Roussel, 1992, Cell.

Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

S. Hanks, X. Zhang, M. Calalb, 1996, Biochemical and biophysical research communications.

Signaling through focal adhesion kinase

S. Hanks, T. Polte, 1997, BioEssays : news and reviews in molecular, cellular and developmental biology.

Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2

S. Hanks, D. W. Fry, P. Ruest, 1999, Molecular and Cellular Biology.

Identification of p130Cas as a Mediator of Focal Adhesion Kinase–promoted Cell Migration

S. Hanks, J. Guan, D. Han, 1998, The Journal of cell biology.

Selective insolubility of active hsp70 gene chromatin.

S. Hanks, M. G. Riggs, 1986, Biochimica et biophysica acta.

PCAF Lysine Acetyltransferase

F. Tamanoi, K. Jacobson, Mark A Sussman, 2008 .

Focal adhesion kinase modulates cell adhesion strengthening via integrin activation.

Andrés J. García, S. Hanks, D. Dumbauld, 2009, Molecular biology of the cell.

Src transformation of colonic epithelial cells: Enhanced anchorage‐independent growth in an Apc+/min background

S. Hanks, J. Brábek, Sabata S. Constancio‐Lund, 2009, Molecular carcinogenesis.

Assaying protein kinase activity.

S. Hanks, J. Brábek, 2004, Methods in molecular biology.

Genomic analysis of the eukaryotic protein kinase superfamily: a perspective

S. Hanks, Steven K Hanks, 2003, Genome Biology.

Regulation and localization of CAS substrate domain tyrosine phosphorylation.

S. Hanks, N. Shin, Jiong Wu, 2004, Cellular signalling.

Global impact of oncogenic Src on a phosphotyrosine proteome.

A. Pandey, R. Chaerkady, S. Hanks, 2008, Journal of proteome research.

Subsets of the Major Tyrosine Phosphorylation Sites in Crk-associated Substrate (CAS) Are Sufficient to Promote Cell Migration*

J. Schneider-Mergener, M. Ritchie, S. Hanks, 2004, Journal of Biological Chemistry.

Structural and functional insights into the interaction between the Cas family scaffolding protein p130Cas and the focal adhesion-associated protein paxillin

S. Hanks, Darcie J. Miller, D. Donato, 2017, The Journal of Biological Chemistry.

p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells.

S. Hanks, Edmondson, Anna C Cunningham-Edmondson, 2009, Breast cancer.

Global Phosphotyrosine Proteomics Identifies PKCδ as a Marker of Responsiveness to Src Inhibition in Colorectal Cancer

R. Coffey, S. Hanks, W. McDonald, 2013, PloS one.

Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family.

S. Hanks, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Eukaryotic protein kinases

S. Hanks, 1991 .

p130CAS Is Required for Netrin Signaling and Commissural Axon Guidance

Y. Rao, Jane Y. Wu, S. Hanks, 2007, The Journal of Neuroscience.

Focal adhesion kinase‐dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions

Andrés J. García, S. Hanks, D. Dumbauld, 2010, Biology of the cell.

Cloning of a Xenopus laevis cDNA encoding focal adhesion kinase (FAK) and expression during early development.

S. Hanks, X. Zhang, C. Wright, 1995, Gene.

The Signaling and Biological Implications of FAK Overexpression in Cancer

S. Hanks, P. F. Siesser, 2006, Clinical Cancer Research.

Relationship between histone phosphorylation and premature chromosome condensation.

S. Hanks, P. Rao, L. Rodriguez, 1983, Experimental cell research.

The Ultrastructural Organization of Prematurely Condensed Chromosomes

S. Hanks, W. Hittelman, S. Gollin, 1984, Journal of Cell Science.

Induction of premature chromosome condensation at high frequency following polyethylene glycol-mediated fusion of lectin-bound cells.

S. Hanks, D. B. Brown, P. Rao, 1982, Experimental cell research.

Focal adhesion kinase promotes phospholipase C-γ1 activity

S. Hanks, G. Carpenter, A. Chattopadhyay, 1999 .

Focal adhesion kinase promotes phospholipase C-gamma1 activity.

S. Hanks, X. Zhang, G. Carpenter, 1999, Proceedings of the National Academy of Sciences of the United States of America.

T Cell Receptor- and Ri Integrin-mediated Signals Synergize to Induce Tyrosine Phosphorylation of Focal Adhesion Kinase (pp125FAK) in Human T Cells

S. Hanks, L. Burkly, J. Maguire, 2003 .

Nephrocystin-conserved Domains Involved in Targeting to Epithelial Cell-Cell Junctions, Interaction with Filamins, and Establishing Cell Polarity*

M. Ritchie, S. Hanks, Rebecca S. Dise, 2002, The Journal of Biological Chemistry.

Podosome dynamics and location in vascular smooth muscle cells require CLASP‐dependent microtubule bending

S. Hanks, N. Efimova, I. Kaverina, 2016, Cytoskeleton.

An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans.

S. Hanks, P. Ruest, Michael A. Miller, 2003, Genes & development.

CD98 modulates integrin β1 function in polarized epithelial cells

A. Pozzi, S. Hanks, Dong Chen, 2005, Journal of Cell Science.

Roles played by a subset of integrin signaling molecules in cadherin-based cell–cell adhesion

S. Hanks, M. Matsuda, K. Kurokawa, 2004, The Journal of cell biology.

Correlations between the expression, phosphotyrosine content and enzymatic activity of focal adhesion kinase, pp125FAK, in tumor and nontransformed cells.

S. Hanks, D. W. Fry, B. E. Withers, 1996, Cancer biochemistry biophysics.

PTPe (RPTPe and Cyt-PTPe)

F. Tamanoi, K. Jacobson, Mark A Sussman, 2012 .

p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells

S. Hanks, Anna C Cunningham-Edmondson, 2009 .

T cell receptor- and beta 1 integrin-mediated signals synergize to induce tyrosine phosphorylation of focal adhesion kinase (pp125FAK) in human T cells

S. Hanks, L. Burkly, G. V. van Seventer, 1995, The Journal of experimental medicine.