M. Laster

发表

Polyhalogenated and perfluorinated compounds that disobey the Meyer-Overton hypothesis.

E. Eger, D. Koblin, B. Chortkoff, 1994, Anesthesia and analgesia.

Minimum alveolar anesthetic concentration of fluorinated alkanols in rats: relevance to theories of narcosis.

A. Pohorille, E. Eger, J. Trudell, 1999, Anesthesia and analgesia.

Isoflurane Suppresses Stress-enhanced Fear Learning in a Rodent Model of Post–Traumatic Stress Disorder

M. Fanselow, E. Eger, M. Laster, 2009, Anesthesiology.

No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during isoflurane anesthesia in rats.

I J Rampil, I. Rampil, M. Laster, 1992, Anesthesiology.

Naloxone Does Not Increase the Minimum Alveolar Anesthetic Concentration of Sevoflurane in Mice

E. Eger, M. Laster, J. Sonner, 2006, Anesthesia and analgesia.

Acetaminophen Predisposes to Renal and Hepatic Injury from Compound A in the Fasting Rat

E. Eger, M. Laster, D. Gong, 1997, Anesthesia and analgesia.

Nephrotoxicity of Sevoflurane Versus Desflurane Anesthesia in Volunteers

R. Weiskopf, E. Eger, D. Koblin, 1997, Anesthesia and analgesia.

Insulin Decreases Isoflurane Minimum Alveolar Anesthetic Concentration in Rats Independently of an Effect on the Spinal Cord

B. Orser, E. Eger, M. Laster, 2004, Anesthesia and analgesia.

Studies of the mechanism of nephrotoxicity of compound A in rats

E. Eger, M. Laster, R. Kerschmann, 1997, Journal of Anesthesia.

Metabolism of Compound A by Renal Cysteine-S-Conjugate beta-Lyase Is Not the Mechanism of Compound A-Induced Renal Injury in the Rat

E. Eger, M. Laster, R. Kerschmann, 1996, Anesthesia and analgesia.

The Ventilatory Stimulant Doxapram Inhibits TASK Tandem Pore (K2P) Potassium Channel Function but Does Not Affect Minimum Alveolar Anesthetic Concentration

Joseph F. Cotten, E. Eger, M. Laster, 2006, Anesthesia and analgesia.

Do Dopamine Receptors Mediate Part of MAC?

E. Eger, M. Laster, J. Sonner, 2006, Anesthesia and analgesia.

Comparison of Kinetics of Sevoflurane and Isoflurane in Humans

R. Weiskopf, E. Eger, M. Laster, 1991, Anesthesia and analgesia.

Chirality in Anesthesia I: Minimum Alveolar Concentration of Secondary Alcohol Enantiomers

E. Eger, M. Laster, J. Sonner, 2006, Anesthesia and Analgesia.

The Effect of Anesthetic Duration on Kinetic and Recovery Characteristics of Desflurane Versus Sevoflurane, and on the Kinetic Characteristics of Compound A, in Volunteers

R. Weiskopf, E. Eger, D. Koblin, 1998, Anesthesia and analgesia.

Comparison of Kinetics of Sevoflurane and Isoflurane in Humans

R. Weiskopf, E. Eger, M. Laster, 1991, Anesthesia and analgesia.

R. Weiskopf, E. Eger, D. Koblin, 1997, Anesthesia and analgesia.

Carbon Monoxide Production from Degradation of Desflurane, Enflurane, Isoflurane, Halothane, and Sevoflurane by Soda Lime and Baralyme Registered Trademark

E. Eger, B. Chortkoff, M. Laster, 1995, Anesthesia and analgesia.

Fires from the Interaction of Anesthetics with Desiccated Absorbent

E. Eger, M. Laster, Patricia Roth, 2004, Anesthesia and analgesia.

Absorbents Differ Enormously in Their Capacity to Produce Compound A and Carbon Monoxide

E. Eger, M. Laster, R. Dudziak, 2000, Anesthesia and analgesia.

The elimination of sodium and potassium hydroxides from desiccated soda lime diminishes degradation of desflurane to carbon monoxide and sevoflurane to compound A but does not compromise carbon dioxide absorption.

R. Weiskopf, E. Eger, M. Laster, 1999, Anesthesia and analgesia.

Dehydration of Baralyme[registered sign] Increases Compound A Resulting from Sevoflurane Degradation in a Standard Anesthetic Circuit Used to Anesthetize Swine

R. Weiskopf, E. Eger, M. Laster, 1997, Anesthesia and analgesia.

Baralyme[registered sign] Dehydration Increases and Soda Lime Dehydration Decreases the Concentration of Compound A Resulting from Sevoflurane Degradation in a Standard Anesthetic Circuit

R. Weiskopf, E. Eger, M. Laster, 1997, Anesthesia and analgesia.

Obesity Modestly Affects Inhaled Anesthetic Kinetics in Humans

E. Eger, M. Laster, L. Saidman, 2008, Anesthesia and analgesia.

Women Appear to Have the Same Minimum Alveolar Concentration as Men: A Retrospective Study

E. Eger, M. Laster, J. Sonner, 2003, Anesthesiology.

Nephrotoxicity in Rats Undergoing a One-Hour Exposure to Compound A

M. Laster, R. Kerschmann, J. Martin, 1995, Anesthesia and analgesia.

What Solvent Best Represents the Site of Action of Inhaled Anesthetics in Humans, Rats, and Dogs?

E. Eger, D. Koblin, M. Laster, 1991, Anesthesia and analgesia.

Absorption and Degradation of Sevoflurane and Isoflurane in a Conventional Anesthetic Circuit

E. Eger, M. Laster, Jin Liu, 1991, Anesthesia and analgesia.

Concentrations of Isoflurane Exceeding Those Used Clinically Slightly Increase the Affinity of Methane, but Not Toluene, for Water

E. Eger, M. Laster, C. Buffington, 2007, Anesthesia and analgesia.

A cutoff in potency exists in the perfluoroalkanes.

E. Eger, D. Koblin, B. Chortkoff, 1994, Anesthesia and analgesia.

Increasing the Duration of Isoflurane Anesthesia Decreases the Minimum Alveolar Anesthetic Concentration in 7-Day-Old but Not in 60-Day-Old Rats

E. Eger, M. Laster, G. Stratmann, 2009, Anesthesia and analgesia.

Cardiovascular actions of desflurane with and without nitrous oxide during spontaneous ventilation in humans.

R. Weiskopf, E. Eger, I. Rampil, 1991, Anesthesia and analgesia.

A method for testing for epinephrine-induced arrhythmias in rats.

E. Eger, M. Laster, B. Johnson, 1990, Anesthesia and analgesia.

Recovery and Kinetic Characteristics of Desflurane and Sevoflurane in Volunteers after 8-h Exposure, including Kinetics of Degradation Products

R. Weiskopf, E. Eger, M. Laster, 1997, Anesthesiology.

Biotransformation of Halothane, Enflurane, Isoflurane, and Desflurane to Trifluoroacetylated Liver Proteins: Association Between Protein Acylation and Hepatic Injury

E. Eger, M. Laster, D. Gong, 1997, Anesthesia and analgesia.

Toxicity of Compound A in Rats: Effect of a 3‐Hour Administration

E. Eger, M. Laster, L. Ferrell, 1994, Anesthesiology.

Toxicity of Compound A in Rats: Effect of Increasing Duration of Administration

E. Eger, M. Laster, L. Ferrell, 1994, Anesthesiology.

Metabolism of Compound A by Renal Cysteine-S-Conjugate beta-Lyase Is Not the Mechanism of Compound A-Induced Renal Injury in the Rat

E. Eger, M. Laster, R. Kerschmann, 1996, Anesthesia and analgesia.

Factors Affecting Production of Compound A from the Interaction of Sevoflurane with Baralyme@ and Soda Lime

E. Eger, M. Laster, I. Ionescu, 2003 .

Dehydration of Baralyme[registered sign] Increases Compound A Resulting from Sevoflurane Degradation in a Standard Anesthetic Circuit Used to Anesthetize Swine

R. Weiskopf, E. Eger, M. Laster, 1997, Anesthesia and analgesia.

Compound A Induces Sister Chromatid Exchanges in Chinese Hamster Ovary Cells

E. Eger, M. Laster, D. Gong, 1997, Anesthesiology.

Factors Affecting Production of Compound A from the Interaction of Sevoflurane with Baralyme Registered Trademark and Soda Lime

E. Eger, M. Laster, P. Ionescu, 1996, Anesthesia and analgesia.

Nonhalogenated Alkanes Cyclopropane and Butane Affect Neurotransmitter-gated Ion Channel and G-protein–coupled Receptors: Differential Actions on GABAA and Glycine Receptors

E. Eger, M. Laster, R. Harris, 2002, Anesthesiology.

Molecular properties of the "ideal" inhaled anesthetic: studies of fluorinated methanes, ethanes, propanes, and butanes.

E. Eger, D. Koblin, B. Chortkoff, 1994, Anesthesia and analgesia.

Anesthetic Properties of Carbon Dioxide in the Rat

E. Eger, M. Laster, J. Sonner, 2007, Anesthesia and analgesia.

Isoflurane causes anterograde but not retrograde amnesia for pavlovian fear conditioning.

M. Fanselow, E. Eger, R. Dutton, 2002, Anesthesiology.

Specific Gravities of Desflurane, Enflurane, Halothane, Isoflurane, and Sevoflurane

E. Eger, M. Laster, Z. Fang, 1994, Anesthesia and analgesia.

Anesthetic and Convulsant Properties of Aromatic Compounds and Cycloalkanes: Implications for Mechanisms of Narcosis

D. Koblin, M. Laster, M. Halsey, 1996, Anesthesia and analgesia.

Nonimmobilizers and transitional compounds may produce convulsions by two mechanisms.

E. Eger, D. Koblin, M. Laster, 1999, Anesthesia and analgesia.

In rats breathing from a nonrebreathing system, substitution of desflurane for isoflurane toward the end of anesthesia incompletely restores the time of recovery toward that of desflurane.

R. Weiskopf, E. Eger, M. Laster, 1998, Anesthesia and analgesia.

The neuromuscular effects of desflurane, alone and combined with pancuronium or succinylcholine in humans.

R. Weiskopf, E. Eger, T. Heier, 1991, Anesthesiology.

Inhaled Anesthetics Do Not Combine to Produce Synergistic Effects Regarding Minimum Alveolar Anesthetic Concentration in Rats

E. Eger, D. Raines, M. Laster, 2008, Anesthesia and analgesia.

Blockade of Acetylcholine Receptors Does Not Change the Dose of Etomidate Required to Produce Immobility in Rats

E. Eger, M. Laster, J. Sonner, 2007, Anesthesia and analgesia.

Lidocaine, MK-801, and MAC

E. Eger, M. Laster, J. Sonner, 2007, Anesthesia and analgesia.

Determination of the EC50 Amnesic Concentration of Etomidate and Its Diffusion Profile in Brain Tissue: Implications for In Vitro Studies

R. Pearce, E. Eger, M. Laster, 2007, Anesthesiology.

Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics.

E. Eger, M. Laster, J. Kendig, 2002 .

Minimum Alveolar Anesthetic Concentration Values for the Enantiomers of Isoflurane Differ Minimally

E. Eger, D. Koblin, M. Laster, 1997, Anesthesia and analgesia.

Blockade of 5-HT2A Receptors May Mediate or Modulate Part of the Immobility Produced by Inhaled Anesthetics

E. Eger, M. Laster, J. Sonner, 2003, Anesthesia and analgesia.

Anesthetic Properties of Some Fluorinated Oxolanes and Oxetanes

E. Eger, M. Laster, Y. Lou, 2007, Anesthesia and analgesia.

Electrical stimulation as a substitute for the tail clamp in the determination of minimum alveolar concentration.

E. Eger, M. Laster, Jin Liu, 1993 .

Maturation Decreases Ethanol Minimum Alveolar Anesthetic Concentration (MAC) More than Desflurane MAC in Rats

E. Eger, M. Laster, D. Gong, 1997, Anesthesia and analgesia.

Halothane and Isoflurane Have Additive Minimum Alveolar Concentration (MAC) Effects in Rats

E. Eger, M. Laster, J. Sonner, 2003, Anesthesia and analgesia.

Mouse strain modestly influences minimum alveolar anesthetic concentration and convulsivity of inhaled compounds.

E. Eger, M. Laster, D. Gong, 1999, Anesthesia and analgesia.

Ammonia Has Anesthetic Properties

E. Eger, M. Laster, J. Sonner, 2007, Anesthesia and analgesia.

Short-Term Memory Resists the Depressant Effect of the Nonimmobilizer 1-2-Dichlorohexafluorocyclobutane (2N) More than Long-Term Memory

M. Fanselow, E. Eger, R. Dutton, 2002, Anesthesia and analgesia.

Short-Term Memory Resists the Depressant Effect of the Nonimmobilizer 1-2-Dichlorohexafluorocyclobutane ( 2 N ) More than Long-Term Memory

M. Fanselow, E. Eger, R. Dutton, 2002 .

Isoflurane Antagonizes the Capacity of Flurothyl or 1,2-Dichlorohexafluorocyclobutane to Impair Fear Conditioning to Context and Tone

R. Pearce, M. Fanselow, E. Eger, 2003, Anesthesia and analgesia.

The Concentration of Isoflurane Required to Suppress Learning Depends on the Type of Learning

M. Fanselow, E. Eger, R. Dutton, 2001, Anesthesiology.

Contrasting Roles of the N-Methyl-d-Aspartate Receptor in the Production of Immobilization by Conventional and Aromatic Anesthetics

E. Eger, R. Dutton, D. Raines, 2006, Anesthesia and analgesia.

Electrical Stimulation as a Substitute for the Tail Clamp in the Determination of Minimum Alveolar Concentration

E. Eger, M. Laster, Jin Liu, 1993, Anesthesia and analgesia.

Pharmacokinetics do not explain the absence of an anesthetic effect of perfluoropropane or perfluoropentane.

E. Eger, D. Koblin, B. Chortkoff, 1994, Anesthesia and analgesia.

Anesthesia by n-alkanes not consistent with the Meyer-Overton hypothesis: determinations of the solubilities of alkanes in saline and various lipids.

E. Eger, D. Koblin, M. Laster, 1993 .

Anesthetic Potencies of n-Alkanols: Results of Additivity and Solubility Studies Suggest a Mechanism of Action Similar to That for Conventional Inhaled Anesthetics

E. Eger, B. Chortkoff, M. Laster, 1997, Anesthesia and analgesia.

Anesthesia by n‐Alkanes Not Consistent with the Meyer‐Overton Hypothesis: Determinations of the Solubilities of Alkanes in Saline and Various Lipids

E. Eger, D. Koblin, M. Laster, 1993, Anesthesia and analgesia.

The Convulsant and Anesthetic Properties of Cis-Trans Isomers of 1,2-Dichlorohexafluorocyclobutane and 1,2-Dichloroethylene

E. Eger, D. Koblin, M. Laster, 2001, Anesthesia and analgesia.

Rat Strain Minimally Influences Anesthetic and Convulsant Requirements of Inhaled Compounds in Rats

E. Eger, M. Laster, P. Ionescu, 1998, Anesthesia and analgesia.

Inhibition of Spinal Protein Kinase C-ε or -γ Isozymes Does Not Affect Halothane Minimum Alveolar Anesthetic Concentration in Rats

E. Eger, M. Laster, J. Kendig, 2004 .

&bgr;3-Containing Gamma-Aminobutyric AcidA Receptors Are Not Major Targets for the Amnesic and Immobilizing Actions of Isoflurane

E. Eger, M. Laster, R. Harris, 2005, Anesthesia and analgesia.

A Comparison of the Molecular Bases for N-Methyl-d-Aspartate-Receptor Inhibition Versus Immobilizing Activities of Volatile Aromatic Anesthetics

E. Eger, D. Raines, M. Laster, 2009, Anesthesia and analgesia.

A method for recording single unit activity in lumbar spinal cord in rats anesthetized with nitrous oxide in a hyperbaric chamber

E. Eger, R. Dutton, M. Laster, 2007, Journal of Neuroscience Methods.

Do N-Methyl-d-Aspartate Receptors Mediate the Capacity of Inhaled Anesthetics to Suppress the Temporal Summation that Contributes to Minimum Alveolar Concentration?

E. Eger, R. Dutton, D. Raines, 2006, Anesthesia and analgesia.

Increases in Spinal Cerebrospinal Fluid Potassium Concentration Do Not Increase Isoflurane Minimum Alveolar Concentration in Rats

E. Eger, D. Raines, M. Laster, 2008, Anesthesia and analgesia.

Minimum alveolar concentrations of noble gases, nitrogen, and sulfur hexafluoride in rats : Helium and neon as nonimmobilizers (nonanesthetics)

E. Eger, J. Trudell, D. Koblin, 1998 .

Minimum Alveolar Concentrations of Noble Gases, Nitrogen, and Sulfur Hexafluoride in Rats: Helium and Neon as Nonimmobilizers (Nonanesthetics)

E. Eger, J. Trudell, D. Koblin, 1998, Anesthesia and analgesia.

Hexafluorobenzene Acts in the Spinal Cord, Whereas O-Difluorobenzene Acts in Both Brain and Spinal Cord, to Produce Immobility

E. Eger, D. Raines, M. Laster, 2007, Anesthesia and analgesia.

Spinal N-Methyl-d-Aspartate Receptors May Contribute to the Immobilizing Action of Isoflurane

E. Eger, M. Laster, J. Sonner, 2003, Anesthesia and analgesia.

The Effect of Rigidity, Shape, Unsaturation, and Length on the Anesthetic Potency of Hydrocarbons

E. Eger, M. Laster, E I Eger, 2001, Anesthesia and analgesia.

Is There a Cutoff in Anesthetic Potency for the Normal Alkanes?

E. Eger, D. Koblin, M. Laster, 1993, Anesthesia and analgesia.

Spinal N-methyl-d-aspartate receptors may contribute to the immobilizing action of isoflurane.

E. Eger, M. Laster, J. Sonner, 2003 .

Glycine receptors mediate part of the immobility produced by inhaled anesthetics.

E. Eger, M. Laster, R. Harris, 2003, Anesthesia and analgesia.

The Excitatory and Inhibitory Effects of Nitrous Oxide on Spinal Neuronal Responses to Noxious Stimulation

E. Eger, R. Dutton, M. Laster, 2007, Anesthesia and analgesia.

Temporal Summation Governs Part of the Minimum Alveolar Concentration of Isoflurane Anesthesia

E. Eger, R. Dutton, M. Laster, 2003, Anesthesiology.

Polyhalogenated methyl ethyl ethers: solubilities and anesthetic properties.

E. Eger, D. Koblin, M. Laster, 1999, Anesthesia and analgesia.

Effects of Inhaled Nonimmobilizer, Proconvulsant Compounds on Desflurane Minimum Alveolar Anesthetic Concentration in Rats

E. Eger, D. Koblin, M. Laster, 1997, Anesthesia and analgesia.

Convulsant Activity of Nonanesthetic Gas Combinations

E. Eger, D. Koblin, M. Laster, 1997, Anesthesia and analgesia.

Effect of n-alkane kinetics in rats on potency estimations and the Meyer-Overton hypothesis.

E. Eger, B. Chortkoff, M. Laster, 1994, Anesthesia and analgesia.

Ventilatory Effects of the Nonimmobilizer 1,2-Dichlorohexafluorocyclobutane (2N) in Swine

E. Eger, M. Laster, E. Steffey, 1998, Anesthesia and analgesia.

Nonanesthetics Can Suppress Learning

B. Chortkoff, M. Laster, J. Sonner, 1996, Anesthesia and analgesia.

Visceral Losses of Desflurane, Isoflurane, and Halothane in Swine

E. Eger, I. Rampil, M. Laster, 1991, Anesthesia and analgesia.

The Anesthetic Potencies of Alkanethiols for Rats: Relevance to Theories of Narcosis

E. Eger, J. Trudell, M. Laster, 2000, Anesthesia and analgesia.

Gamma-Aminobutyric AcidA Receptors Do Not Mediate the Immobility Produced by Isoflurane

E. Eger, D. Raines, M. Laster, 2004, Anesthesia and analgesia.

&agr;-2 Adrenoreceptors Probably Do Not Mediate the Immobility Produced by Inhaled Anesthetics

E. Eger, M. Laster, J. Sonner, 2003, Anesthesia and analgesia.

Alterations in Spinal, but Not Cerebral, Cerebrospinal Fluid Na+ Concentrations Affect the Isoflurane Minimum Alveolar Concentration in Rats

E. Eger, M. Laster, J. Sonner, 2007, Anesthesia and analgesia.

Desflurane Does Not Produce Hepatic or Renal Injury in Human Volunteers

R. Weiskopf, E. Eger, I. Rampil, 1992, Anesthesia and analgesia.

Acetylcholine Receptors Do Not Mediate the Immobilization Produced by Inhaled Anesthetics

E. Eger, M. Laster, J. Kendig, 2002, Anesthesia and analgesia.

Antagonism of the 5-HT3 Receptor Does Not Alter Isoflurane MAC in Rats

E. Eger, I. Rampil, M. Laster, 2001, Anesthesiology.

Temperatures in Soda Lime During Degradation of Desflurane, Isoflurane, and Sevoflurane by Desiccated Soda Lime

E. Eger, M. Laster, 2005, Anesthesia and analgesia.

Fractional Distillation of Acid Contaminants from Sevoflurane

E. Eger, M. Laster, D. Gong, 2000, Anesthesia and analgesia.

Anaesthetic properties of dimethylthiourea.

D. Koblin, M. Laster, J. Liu, 1993, British journal of anaesthesia.

Intrathecal Veratridine Administration Increases Minimum Alveolar Concentration in Rats

E. Eger, M. Laster, Manohar Sharma, 2008, Anesthesia and analgesia.

GABAA Receptor Blockade Antagonizes the Immobilizing Action of Propofol but Not Ketamine or Isoflurane in a Dose-Related Manner

M. Laster, J. Sonner, J. Bovill, 2003, Anesthesia and analgesia.

Anesthetic Pharmacology International Society for Anaesthetic Pharmacology Contrasting Roles of the N-methyl-d-aspartate Receptor in the Production of Immobilization by Conventional and Aromatic Anesthetics

R. Dutton, D. Raines, M. Laster, 2022 .

Comparison of Percutaneous Losses of Sevoflurane and Isoflurane in Humans

R. Weiskopf, E. Eger, M. Laster, 1991, Anesthesia and analgesia.

The Minimum Alveolar Anesthetic Concentration of 2-, 3-, and 4-Alcohols and Ketones in Rats: Relevance to Anesthetic Mechanisms

E. Eger, J. Trudell, M. Laster, 2006, Anesthesia and analgesia.

In Vivo 19F Nuclear Magnetic Resonance Brain Studies of Halothane, Isoflurane, and Desflurane

M. Moseley, E. Eger, M. Laster, 1991, Annals of the New York Academy of Sciences.