Jonathan B. Cohen

发表

Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane.

R. Eckenhoff, D. C. Chiara, L. Dangott, 2003, Biochemistry.

Identification of Binding Sites in the Nicotinic Acetylcholine Receptor for [3H]Azietomidate, a Photoactivatable General Anesthetic*

Jonathan B. Cohen, S. Husain, K. Miller, 2004, Journal of Biological Chemistry.

Identification of the bovine gamma-aminobutyric acid type A receptor alpha subunit residues photolabeled by the imidazobenzodiazepine [3H]Ro15-4513.

R. Olsen, D. C. Chiara, Jonathan B. Cohen, 2002, The Journal of biological chemistry.

Multiple Propofol-binding Sites in a γ-Aminobutyric Acid Type A Receptor (GABAAR) Identified Using a Photoreactive Propofol Analog*♦

R. Eckenhoff, D. C. Chiara, Jonathan B. Cohen, 2014, The Journal of Biological Chemistry.

The Agrin/MuSK Signaling Pathway Is Spatially Segregated from the Neuregulin/ErbB Receptor Signaling Pathway at the Neuromuscular Junction

Jonathan B. Cohen, G. Fischbach, J. Trinidad, 2000, The Journal of Neuroscience.

Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2020, The Journal of Biological Chemistry.

Rotational energy transfer in pure HCN and in HCN‐rare gas mixtures by microwave double resonance and pressure broadening

Jonathan B. Cohen, E. B. Wilson, E. Wilson, 1973 .

A-Aminobutyric Acid Type A ( GABA γ Inhibit Etomidate Binding to Numerous Classes of General Anesthetics Protein Structure and Folding :

R. Olsen, D. C. Chiara, Jonathan B. Cohen, 2010 .

Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor.

M. P. Blanton, D. C. Chiara, Jonathan B. Cohen, 2008, Biochemistry.

Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies.

D. Raines, Jonathan B. Cohen, K. Miller, 2020, Anesthesiology.

General Anesthetic Binding Sites in Human (cid:2) 4 (cid:3) 3 (cid:4) (cid:5) -Aminobutyric Acid Type A Receptors (GABA A Rs) *

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2020 .

[3H]Benzophenone photolabeling identifies state-dependent changes in nicotinic acetylcholine receptor structure.

D. C. Chiara, Jonathan B. Cohen, S. Nirthanan, 2007, Biochemistry.

Allyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic.

D. Raines, D. C. Chiara, Jonathan B. Cohen, 2012, Journal of medicinal chemistry.

Microwave double resonance studies of rotational relaxation in polar gases

Jonathan B. Cohen, E. B. Wilson, E. Wilson, 1973 .

Fractionation by velocity sedimentation of Torpedo nicotinic post-synaptic membranes

Jonathan B. Cohen, A. Jeng, P. A. John, 1981 .

Contaminant Exposure and Effects—Terrestrial Vertebrates Database: Trends and Data Gaps for Atlantic Coast Estuaries

Jonathan B. Cohen, M. Ottinger, R. Erwin, 2000 .

Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels.

D. Raines, R. Olsen, Jonathan B. Cohen, 2006, Journal of medicinal chemistry.

Multiple Transmembrane Binding Sites for p-Trifluoromethyldiazirinyl-etomidate, a Photoreactive Torpedo Nicotinic Acetylcholine Receptor Allosteric Inhibitor*

Jonathan B. Cohen, S. Husain, Ayman K. Hamouda, 2011, The Journal of Biological Chemistry.

Gating-enhanced Accessibility of Hydrophobic Sites within the Transmembrane Region of the Nicotinic Acetylcholine Receptor's δ-Subunit

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2005, Journal of Biological Chemistry.

p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels.

Joseph F. Cotten, D. Raines, R. Olsen, 2010, Journal of medicinal chemistry.

α‐Conotoxin GI benzoylphenylalanine derivatives

V. S. Pashkov, D. C. Chiara, Jonathan B. Cohen, 2006 .

Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands.

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2017, European journal of medicinal chemistry.

Hydrolysis by Acetylcholinesterase. Trimethyl and Methyl Subsites

Saul G. Cohen, Jonathan B. Cohen, F. Hasan, 1979 .

Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor.

D. Lovinger, M. P. Blanton, Jonathan B. Cohen, 2009, Biochemistry.

Identification of Propofol Binding Sites in a Nicotinic Acetylcholine Receptor with a Photoreactive Propofol Analog*

R. Eckenhoff, Jonathan B. Cohen, S. Jayakar, 2013, The Journal of Biological Chemistry.

Numerous Classes of General Anesthetics Inhibit Etomidate Binding to γ-Aminobutyric Acid Type A (GABAA) Receptors*

R. Olsen, D. C. Chiara, Jonathan B. Cohen, 2010, The Journal of Biological Chemistry.

Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β− Interface*

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2015, The Journal of Biological Chemistry.

CONFORMATIONAL TRANSITIONS OF THE MEMBRANE-BOUND CHOLINERGIC RECEPTOR

Jonathan B. Cohen, N. Boyd, 1979 .

A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor

D. C. Chiara, Jonathan B. Cohen, K. Bruzik, 2019, The Journal of Biological Chemistry.

Identifying the lipid-protein interface of the alpha4beta2 neuronal nicotinic acetylcholine receptor: hydrophobic photolabeling studies with 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine.

M. P. Blanton, D. C. Chiara, Jonathan B. Cohen, 2007, Biochemistry.

Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors.

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2019, European journal of medicinal chemistry.

Contributions of Torpedo Nicotinic Acetylcholine Receptor γTrp-55 and δTrp-57 to Agonist and Competitive Antagonist Function*

Jonathan B. Cohen, Yu Xie, 2001, The Journal of Biological Chemistry.

Identification of a GABAA Receptor Anesthetic Binding Site at Subunit Interfaces by Photolabeling with an Etomidate Analog

R. Olsen, D. C. Chiara, Jonathan B. Cohen, 2006, The Journal of Neuroscience.

Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the α1β3γ2 GABAAR Transmembrane Domain

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2019, Molecular Pharmacology.

Specificity of Intersubunit General Anesthetic-binding Sites in the Transmembrane Domain of the Human α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor*♦

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2013, The Journal of Biological Chemistry.

Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2012, Biochemistry.

General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type A Receptors (GABAARs)*

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2016, The Journal of Biological Chemistry.

Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator

Jonathan B. Cohen, Ze-Jun Wang, F. Deba, 2016, Molecular Pharmacology.

The 87K postsynaptic membrane protein from torpedo is a protein-tyrosine kinase substrate homologous to dystrophin

R. Huganir, Jonathan B. Cohen, K. Wagner, 1993, Neuron.

Neuregulin Inhibits Acetylcholine Receptor Aggregation in Myotubes*

Jonathan B. Cohen, J. Trinidad, 2004, Journal of Biological Chemistry.

Interactions of the Rapsyn RING-H2 Domain with Dystroglycan*

Jonathan B. Cohen, M. Bartoli, M. Ramarao, 2001, The Journal of Biological Chemistry.

Role of Rapsyn Tetratricopeptide Repeat and Coiled-coil Domains in Self-association and Nicotinic Acetylcholine Receptor Clustering*

Jonathan B. Cohen, M. Ramarao, Michael J Bianchetta, 2001, The Journal of Biological Chemistry.

Physostigmine and Galanthamine Bind in the Presence of Agonist at the Canonical and Noncanonical Subunit Interfaces of a Nicotinic Acetylcholine Receptor

Jonathan B. Cohen, T. Kimm, Ayman K. Hamouda, 2013, The Journal of Neuroscience.

Identification of Amino Acids Contributing to High and Low Affinity d-Tubocurarine Sites in the TorpedoNicotinic Acetylcholine Receptor*

D. C. Chiara, Jonathan B. Cohen, 1997, The Journal of Biological Chemistry.

Bupropion binds to two sites in the Torpedo nicotinic acetylcholine receptor transmembrane domain: a photoaffinity labeling study with the bupropion analogue [(125)I]-SADU-3-72.

M. P. Blanton, Jonathan B. Cohen, M. Jansen, 2012, Biochemistry.

[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel.

D. C. Chiara, Jonathan B. Cohen, M. Ziebell, 2009, Biochemistry.

Photoreactive Propofol Analog R ) Identified Using aA ( GABA-Aminobutyric Acid Type A Receptor γ Multiple Propofol-binding Sites in a Neurobiology :

R. Eckenhoff, D. C. Chiara, Jonathan B. Cohen, 2014 .

Studies on the Mode of Action of Cholinergic Agonists at the Molecular Level

H. Lester, J. Changeux, R. Olsen, 1973 .

A potent photoreactive general anesthetic with novel binding site selectivity for GABAA receptors.

Jonathan B. Cohen, K. Miller, K. Bruzik, 2020, European journal of medicinal chemistry.

p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol.

D. Raines, D. C. Chiara, Jonathan B. Cohen, 2011, Journal of medicinal chemistry.

2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels.

R. Olsen, Jonathan B. Cohen, S. Husain, 2003, Journal of Medicinal Chemistry.

Presence of a lattice structure in membrane fragments rich in nicotinic receptor protein from the electric organ of Torpedo marmorata

J. Changeux, Jonathan B. Cohen, J. Cartaud, 1973, FEBS letters.

Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol

J. Steinbach, D. C. Chiara, Jonathan B. Cohen, 2016, Current neuropharmacology.

Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: antagonist footprint and secondary structure prediction.

D. C. Chiara, Jonathan B. Cohen, Deirdre Sullivan, 2002, Molecular pharmacology.

Identification of Sites of Incorporation in the Nicotinic Acetylcholine Receptor of a Photoactivatible General Anesthetic*

J. B. Cohen, Jonathan B. Cohen, M. B. Pratt, 2000, The Journal of Biological Chemistry.

Mapping the Agonist Binding Site of the Nicotinic Acetylcholine Receptor

Jonathan B. Cohen, Deirdre Sullivan, 2000, The Journal of Biological Chemistry.

Probing the Structure of the Nicotinic Acetylcholine Receptor Ion Channel with the Uncharged Photoactivable Compound [3H]Diazofluorene*

M. P. Blanton, A. K. Lala, L. Dangott, 1998, The Journal of Biological Chemistry.

Identification of tryptophan 55 as the primary site of [3H]nicotine photoincorporation in the γ‐subunit of the Torpedo nicotinic acetylcholine receptor

J. B. Cohen, D. C. Chiara, Jonathan B. Cohen, 1998, FEBS letters.

Identification of the Bovine γ-Aminobutyric Acid Type A Receptor α Subunit Residues Photolabeled by the Imidazobenzodiazepine [3H]Ro15-4513*

R. Olsen, D. C. Chiara, Jonathan B. Cohen, 2002, The Journal of Biological Chemistry.

Probing the Structure of the Nicotinic Acetylcholine Receptor with 4-Benzoylbenzoylcholine, a Novel Photoaffinity Competitive Antagonist*

D. C. Chiara, Jonathan B. Cohen, Dong Wang, 2000, The Journal of Biological Chemistry.

Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor

R. Glennon, Jonathan B. Cohen, Ze-Jun Wang, 2015, Molecular Pharmacology.

Identification of Binding Sites in the Nicotinic Acetylcholine Receptor for TDBzl-etomidate, a Photoreactive Positive Allosteric Effector*

D. C. Chiara, Jonathan B. Cohen, S. Husain, 2008, Journal of Biological Chemistry.

Conformational changes in the nicotinic acetylcholine receptor during gating and desensitization.

D. C. Chiara, Jonathan B. Cohen, K. Miller, 2010, Biochemistry.

Photoaffinity Labeling of Nicotinic Receptors: Diversity of Drug Binding Sites!

D. C. Chiara, Jonathan B. Cohen, S. Jayakar, 2014, Journal of Molecular Neuroscience.

Photoaffinity labeling the propofol binding site in GLIC.

R. Eckenhoff, D. C. Chiara, Jonathan B. Cohen, 2013, Biochemistry.

Neurosteroids Allosterically Modulate Binding of the Anesthetic Etomidate to γ-Aminobutyric Acid Type A Receptors*

R. Olsen, D. C. Chiara, Jonathan B. Cohen, 2009, Journal of Biological Chemistry.

Enantiomeric barbiturates bind distinct inter- and intrasubunit binding sites in a nicotinic acetylcholine receptor (nAChR)

Jonathan B. Cohen, Zhiyi Yu, 2017, The Journal of Biological Chemistry.

Competitive Antagonism of Anesthetic Action at the &ggr;-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy

D. Raines, Jonathan B. Cohen, K. Miller, 2017, Anesthesiology.

Etomidate and Etomidate Analog Binding and Positive Modulation of &ggr;-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect

D. Raines, Jonathan B. Cohen, K. Miller, 2018, Anesthesiology.

Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors

D. Raines, Jonathan B. Cohen, K. Miller, 2018, Anesthesiology.

Time-Resolved Photolabeling of the Nicotinic Acetylcholine Receptor by [3H]Azietomidate, an Open-State Inhibitor

D. C. Chiara, Jonathan B. Cohen, S. Husain, 2009, Molecular Pharmacology.

Cholesterol interacts with transmembrane alpha-helices M1, M3, and M4 of the Torpedo nicotinic acetylcholine receptor: photolabeling studies using [3H]Azicholesterol.

M. P. Blanton, D. C. Chiara, Jonathan B. Cohen, 2006, Biochemistry.

Competitive Antagonism of Etomidate Action by Diazepam.

D. Raines, Jonathan B. Cohen, K. Miller, 2020, Anesthesiology.

Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post-synaptic membrane.

L. Kunkel, Jonathan B. Cohen, T. Khurana, 1996, Human molecular genetics.

The 43-kilodalton protein of Torpedo nicotinic postsynaptic membranes: purification and determination of primary structure.

Jonathan B. Cohen, D. McCourt, C. Carr, 1987, Biochemistry.

Mechanism of nicotinic acetylcholine receptor cluster formation by rapsyn.

Jonathan B. Cohen, J B Cohen, M K Ramarao, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Equilibrium binding of [3H]tubocurarine and [3H]acetylcholine by Torpedo postsynaptic membranes: stoichiometry and ligand interactions.

R. Neubig, J. B. Cohen, Jonathan B. Cohen, 1979, Biochemistry.

Acetylcholine and local anesthetic postsynaptic membranes after rem

R. Neubig, Jonathan B. Cohen, E. Krodel, 2016 .

Photoaffinity labeling the torpedo nicotinic acetylcholine receptor with [(3)H]tetracaine, a nondesensitizing noncompetitive antagonist.

Jonathan B. Cohen, N. P. Strnad, Richard E. Middleton, 1999, Molecular pharmacology.

Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: secondary structure implications.

M. P. Blanton, J. B. Cohen, Jonathan B. Cohen, 1994, Biochemistry.

d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor.

J. B. Cohen, Jonathan B. Cohen, S. Pedersen, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Permeability Control and Desensitization by Nicotinic Acetylcholine Receptors

Jonathan B. Cohen, N. P. Strnad, 1987 .