N. Méthot

发表

Structure of the Pore-forming Transmembrane Domain of a Ligand-gated Ion Channel*

M. P. Blanton, N. Méthot, B. D. Ritchie, 2001, The Journal of Biological Chemistry.

Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR*

H. Atkins, N. Sonenberg, B. Vanderhyden, 1999, The Journal of Biological Chemistry.

Fourier transform infrared and hydrogen/deuterium exchange reveal an exchange-resistant core of alpha-helical peptide hydrogens in the nicotinic acetylcholine receptor.

N. Méthot, J. Baenziger, 1995, The Journal of biological chemistry.

Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors.

N. Méthot, D. Riendeau, Daigen Xu, 2007, Bioorganic & medicinal chemistry letters.

Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886.

N. Méthot, D. Riendeau, D. Éthier, 2005, Bioorganic & medicinal chemistry letters.

Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors.

N. Méthot, D. Riendeau, Daigen Xu, 2009, Bioorganic & medicinal chemistry letters.

Trisubstituted ureas as potent and selective mPGES-1 inhibitors.

N. Méthot, D. Riendeau, Daigen Xu, 2011, Bioorganic & medicinal chemistry letters.

Hedgehog Controls Limb Development by Regulating the Activities of Distinct Transcriptional Activator and Repressor Forms of Cubitus interruptus

Konrad Basler, N. Méthot, K. Basler, 1999, Cell.

An absolute requirement for Cubitus interruptus in Hedgehog signaling.

N. Méthot, K. Basler, K Basler, 2001, Development.

Smoothened titania particles to improve radionuclide separation and their application to the development of a novel [68Ge]/[68Ga] generator

N. Méthot, L. Barré, Damien Cressier, 2015 .

In Vivo Inhibition of Serine Protease Processing Requires a High Fractional Inhibition of Cathepsin C

N. Méthot, M. Percival, D. Riendeau, 2008, Molecular Pharmacology.

Inhibition of the Activation of Multiple Serine Proteases with a Cathepsin C Inhibitor Requires Sustained Exposure to Prevent Pro-enzyme Processing*

N. Méthot, M. Percival, D. Riendeau, 2007, Journal of Biological Chemistry.

A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3

N. Sonenberg, N. Méthot, M. Song, 1996, Molecular and cellular biology.

A Caspase Active Site Probe Reveals High Fractional Inhibition Needed to Block DNA Fragmentation*

N. Méthot, Yongxin Han, R. Zamboni, 2004, Journal of Biological Chemistry.

In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: the role of the RNA remotif.

N. Sonenberg, N. Méthot, J. Keene, 1996, RNA.

Deletion of Microsomal Prostaglandin E2 (PGE2) Synthase-1 Reduces Inducible and Basal PGE2 Production and Alters the Gastric Prostanoid Profile*

N. Méthot, M. Percival, D. Riendeau, 2004, Journal of Biological Chemistry.

hydrolysis.required for RNA binding and ATP helicase eukaryotic translation initiation factor The HRIGRXXR region of the DEAD box RNA

N. Sonenberg, N. Méthot, A. Pause, 2013 .

The Saccharomyces cerevisiae translation initiation factor Tif3 and its mammalian homologue, eIF‐4B, have RNA annealing activity.

N. Sonenberg, B. Wittmer, N. Méthot, 1995, The EMBO journal.

Reversible Cysteine Protease Inhibitors Show Promise for a Chagas Disease Cure

N. Méthot, M. Ndao, F. Massé, 2013, Antimicrobial Agents and Chemotherapy.

Cytology of irregular growth forms of Ophiostoma ulmi and Ophiostoma novo-ulmi growing through millipore filter membranes and sterilized elm wood sections

N. Méthot, C. Côté, G. B. Ouellette, 1995 .

Three-dimensional Structure of the Nicotinic Acetylcholine Receptor and Location of the Major Associated 43-kd Cytoskeletal Protein, Determined at 22/ by Low Dose Electron Microscopy and X-ray Diffraction to 12.5

N. Méthot, J. Baenziger, M. McCarthy, 1994 .

Differential Efficacy of Caspase Inhibitors on Apoptosis Markers during Sepsis in Rats and Implication for Fractional Inhibition Requirements for Therapeutics

N. Méthot, Yongxin Han, R. Zamboni, 2004, The Journal of experimental medicine.

Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus.

N. Méthot, K. Basler, Nathalie Méthot, 2000, Development.

The Human Homologue of the Yeast Prt1 Protein Is an Integral Part of the Eukaryotic Initiation Factor 3 Complex and Interacts with p170*

N. Sonenberg, N. Méthot, E. Rom, 1997, The Journal of Biological Chemistry.

The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence

N. Sonenberg, N. Méthot, A. Pause, 1994 .

The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis

N. Sonenberg, N. Méthot, A. Pause, 1993, Molecular and cellular biology.

The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia.

M. Jaramillo, N. Méthot, G. Barber, 1998, Experimental cell research.

Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C.

C. Bayly, N. Méthot, D. Éthier, 2009, Bioorganic & medicinal chemistry letters.

The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence.

N. Sonenberg, N. Méthot, A. Pause, 1994, Molecular and cellular biology.

Dominant negative mutants of mammalian translation initiation factor eIF‐4A define a critical role for eIF‐4F in cap‐dependent and cap‐independent initiation of translation.

N. Sonenberg, N. Méthot, A. Pause, 1994, The EMBO journal.

Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease.

Frédéric Massé, N. Méthot, M. Ndao, 2010, Bioorganic & medicinal chemistry letters.

Secondary Structure Analysis of Individual Transmembrane Segments of the Nicotinic Acetylcholine Receptor by Circular Dichroism and Fourier Transform Infrared Spectroscopy*

M. P. Blanton, N. Méthot, J. Baenziger, 1998, The Journal of Biological Chemistry.

Fourier Transform Infrared and Hydrogen/Deuterium Exchange Reveal an Exchange-resistant Core of α -Helical Peptide Hydrogens in the Nicotinic Acetylcholine Receptor (*)

N. Méthot, J. Baenziger, 1995, The Journal of Biological Chemistry.

MF63 [2-(6-Chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation

N. Méthot, D. Riendeau, P. Clark, 2008, Journal of Pharmacology and Experimental Therapeutics.

Induced responses on algal growth and phosphate removal by three molecular weight DOM fractions from a secondary effluent

N. Méthot, J. Noüe, P. Couture, 1986 .

Secondary structure of the exchange-resistant core from the nicotinic acetylcholine receptor probed directly by infrared spectroscopy and hydrogen/deuterium exchange.

N. Méthot, J. Baenziger, 1998, Biochemistry.

Structure of both the ligand- and lipid-dependent channel-inactive states of the nicotinic acetylcholine receptor probed by FTIR spectroscopy and hydrogen exchange.

N. Méthot, J. Baenziger, C. Demers, 1995, Biochemistry.