T. Lewis

发表

Mechanisms of channel gating of the ligand‐gated ion channel superfamily inferred from protein structure

P. Schofield, N. Absalom, T. Lewis, 2004, Experimental physiology.

Structure‐Function Relationships of the Human Glycine Receptor: Insights from Hyperekplexia Mutations

P. Schofield, T. Lewis, 1999, Annals of the New York Academy of Sciences.

Analyzing Ion Permeation in Channels and Pumps Using Patch‐Clamp Recording

P. H. Barry, T. Lewis, A. Moorhouse, 2015 .

A Single P-loop Glutamate Point Mutation to either Lysine or Arginine Switches the Cation–Anion Selectivity of the CNGA2 Channel

T. Lewis, A. Moorhouse, K. Pierce, 2006, The Journal of general physiology.

Gating mechanisms in Cys-loop receptors

P. Schofield, T. Lewis, Jennie M E Cederholm, 2009, European Biophysics Journal.

Ultrastructure of sarcoballs on the surface of skinned amphibian skeletal muscle fibres

P. Junankar, T. Lewis, A. Dulhunty, 1992, Journal of Muscle Research & Cell Motility.

Identification of a New Ligand Binding Domain in the α1 Subunit of the Inhibitory Glycine Receptor

P. Schofield, T. Lewis, J. Lynch, 1999, Journal of neurochemistry.

Mixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptors

T. Lewis, A. J. Thompson, G. Johnston, 2012, Neuropharmacology.

A Hydrophobic Area of the GABA ρ1 Receptor Containing Phenylalanine 124 Influences Both Receptor Activation and Deactivation

J. Hanrahan, N. Absalom, T. Lewis, 2015, Journal of Molecular Neuroscience.

Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in α1 Glycine Receptor Channels*

T. Lewis, J. A. Peters, J. Lambert, 2009, Journal of Biological Chemistry.

Replicable Expansion and Differentiation of Neural Precursors from Adult Canine Skin

P. Sachdev, T. Lewis, M. Valenzuela, 2017, Stem cell reports.

The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type

T. Lewis, D. Colquhoun, L. Sivilotti, 1997, The Journal of physiology.

Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB).

M. Owen, R. Snell, P. Schofield, 2002, Human molecular genetics.

In vivo somatic delivery of plasmid DNA and retrograde transport to obtain cell‐specific gene expression in the central nervous system

R. Morris, T. Lewis, A. Pisano, 2004, Journal of neurochemistry.

Role of Charged Residues in Coupling Ligand Binding and Channel Activation in the Extracellular Domain of the Glycine Receptor*

P. Schofield, N. Absalom, T. Lewis, 2003, Journal of Biological Chemistry.

Pore Structure of the Cys-loop Ligand-gated Ion Channels

P. Schofield, N. Absalom, T. Lewis, 2009, Neurochemical Research.

Ligand Binding at the α4-α4 Agonist-Binding Site of the α4β2 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State

N. Absalom, T. Lewis, D. Indurthi, 2016, PloS one.

Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel

T. Lewis, A. Moorhouse, W. Qu, 2005, European Biophysics Journal.

An optimised 3 M KCl salt-bridge technique used to measure and validate theoretical liquid junction potential values in patch-clamping and electrophysiology

T. Lewis, A. Moorhouse, P. Barry, 2013, European Biophysics Journal.

Immunolabelling for VDAC, the mitochondrial voltage-dependent anion channel, on sarcoplasmic reticulum from amphibian skeletal muscle

T. Lewis, A. Bretag, M. Roberts, 1994, Neuroscience Letters.

Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry

N. Absalom, T. Lewis, D. Indurthi, 2019, Pharmacological research.

Compound heterozygosity and nonsense mutations in the α1-subunit of the inhibitory glycine receptor in hyperekplexia

M. Owen, R. Snell, P. Schofield, 2001, Human Genetics.

Kinetic Determinants of Agonist Action at the Recombinant Human Glycine Receptor

P. Schofield, T. Lewis, Annette M. L. McClellan, 2003, The Journal of physiology.

Covalent Trapping of Methyllycaconitine at the α4-α4 Interface of the α4β2 Nicotinic Acetylcholine Receptor

Joseph I. Ambrus, N. Absalom, T. Lewis, 2013, The Journal of Biological Chemistry.

Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor

N. Absalom, T. Lewis, R. Griffith, 2010, Journal of neurochemistry.

Covalent Trapping of Methyllycaconitine at the (cid:1) 4- (cid:1) 4 Interface of the (cid:1) 4 (cid:2) 2 Nicotinic Acetylcholine Receptor ANTAGONIST BINDING SITE AND MODE OF RECEPTOR INHIBITION REVEALED

Joseph I. Ambrus, N. Absalom, T. Lewis, 2013 .

Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels.

P. Schofield, T. Lewis, A. Moorhouse, 2008, Biophysical journal.

Properties of human glycine receptors containing the hyperekplexia mutation α1(K276E), expressed in Xenopus oocytes

T. Lewis, D. Colquhoun, L. Sivilotti, 1998, The Journal of physiology.

Conditional Upregulation of KCC2 selectively enhances neuronal inhibition during seizures

J. Power, Kayo Nakamura, J. Nabekura, 2018, bioRxiv.

External divalent cations increase anion–cation permeability ratio in glycine receptor channels

T. Lewis, A. Moorhouse, J. Carland, 2010, Pflügers Archiv - European Journal of Physiology.

Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in α1 Glycine Receptor Channels*

T. Lewis, J. A. Peters, J. Lambert, 2009, Journal of Biological Chemistry.