K. Takata

P. Gebicke-haerter, K. Takata, Y. Kitamura, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.

P. Gebicke-haerter, K. Takata, Y. Kitamura, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification of glutamic acid decarboxylase gene and distribution of GABAergic nervous system in the planarian Dugesia japonica

K. Nishimura, K. Takata, Y. Kitamura, 2008, Neuroscience.

Peripheral Blood-Derived Microglia-Like Cells Decrease Amyloid-β Burden and Ameliorate Cognitive Impairment in a Mouse Model of Alzheimer's Disease.

Susumu Nakata, K. Takata, Y. Kitamura, 2019, Journal of Alzheimer's disease : JAD.

Bone-Marrow-Derived Microglia-Like Cells Ameliorate Brain Amyloid Pathology and Cognitive Impairment in a Mouse Model of Alzheimer's Disease.

Susumu Nakata, K. Takata, Y. Kitamura, 2018, Journal of Alzheimer's disease : JAD.

Morphological change by overexpression of D385A dominant negative presenilin 1 in human neuroblastoma SH-SY5Y cells.

K. Takata, Y. Kitamura, D. Tsuchiya, 2006, Journal of pharmacological sciences.

Human GPM6A is associated with differentiation and neuronal migration of neurons derived from human embryonic stem cells.

K. Takata, Y. Kitamura, T. Taniguchi, 2009, Stem cells and development.

Inhibition of mouse GPM6A expression leads to decreased differentiation of neurons derived from mouse embryonic stem cells.

K. Takata, Y. Kitamura, T. Taniguchi, 2008, Stem cells and development.

Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ

K. Takata, Y. Kitamura, S. Shimohama, 2020, Neuroscience.

Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome

F. Ginhoux, K. Yamakawa, K. Takata, 2019, Brain pathology.

Possible involvement of both endoplasmic reticulum-and mitochondria-dependent pathways in thapsigargin-induced apoptosis in human neuroblastoma SH-SY5Y cells.

K. Takata, Y. Kitamura, D. Tsuchiya, 2003, Journal of pharmacological sciences.

Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice.

M. Tominaga, K. Takata, K. Nishimura, 2019, European journal of pharmacology.

Targeting innate immunity for neurodegenerative disorders of the central nervous system

F. Ginhoux, M. Lynch, C. Holmes, 2016, Journal of neurochemistry.

Possible Involvement of ER Chaperone Grp78 on Reduced Formation of Amyloid‐β Deposits

M. Smith, P. Gebicke-haerter, K. Takata, 2002, Annals of the New York Academy of Sciences.

α4 nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior

K. Takata, Y. Kitamura, D. Yanagisawa, 2016, Neurochemistry International.

Proteasome inhibitors protect against degeneration of nigral dopaminergic neurons in hemiparkinsonian rats.

K. Takata, Y. Kitamura, T. Taniguchi, 2005, Journal of pharmacological sciences.

Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse model of Alzheimer's disease

K. Takata, Y. Kitamura, S. Shimohama, 2018, Neurobiology of Aging.

Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone‐induced Parkinson's disease models

K. Takata, Y. Kitamura, T. Taniguchi, 2009, Journal of neuroscience research.

CG13250, a novel bromodomain inhibitor, suppresses proliferation of multiple myeloma cells in an orthotopic mouse model.

J. Strovel, Susumu Nakata, K. Takata, 2017, Biochemical and biophysical research communications.

Possible involvement of Wiskott–Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease

K. Takata, Y. Kitamura, D. Tsuchiya, 2003, Neuroscience Letters.

Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole.

K. Takata, Y. Kitamura, T. Taniguchi, 2001, European journal of pharmacology.

Reconstruction of dopaminergic neural network and locomotion function in planarian regenerates

K. Yoshimoto, K. Takata, Y. Kitamura, 2007, Developmental neurobiology.

Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4‐phenylbutyrate, a chemical chaperone

Kazuyuki Takata, Shun Shimohama, Takashi Yanagida, 2007, Journal of neurochemistry.

PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson’s disease rat model

Kazuyuki Takata, Shun Shimohama, Takashi Yanagida, 2006, Neurobiology of Disease.

Oxidative stress induction of DJ-1 protein

K. Takata, Y. Kitamura, D. Yanagisawa, 2017 .

Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

K. Takata, Y. Kitamura, D. Yanagisawa, 2009, Oxidative medicine and cellular longevity.

Synergistic effect of galantamine on nicotine-induced neuroprotection in hemiparkinsonian rat model

K. Takata, Y. Kitamura, T. Taniguchi, 2008, Neuroscience Research.

Microglial Amyloid-β1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer's Disease

K. Takata, Y. Kitamura, S. Shimohama, 2012, International journal of Alzheimer's disease.

Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: tangle formation, amyloid-β, and microglia in Alzheimer's disease.

K. Takata, Y. Kitamura, 2012, Journal of pharmacological sciences.

Preparation and Characterization of Microglia-Like Cells Derived from Rat, Mouse, and Human Bone Marrow Cells for Therapeutic Strategy of Alzheimer's Disease

K. Takata, Y. Kitamura, S. Shimohama, 2011 .

High mobility group box protein‐1 inhibits microglial Aβ clearance and enhances Aβ neurotoxicity

K. Takata, Y. Kitamura, D. Tsuchiya, 2004 .

[Pathological changes induced by amyloid-β in Alzheimer's disease].

K. Takata, Y. Kitamura, T. Taniguchi, 2011, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Deglycosylated anti‐amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration

M. Mattson, P. Aisen, K. Takata, 2007, The European journal of neuroscience.

Microglial activation around amyloid-β deposits in mouse and rat models

K. Takata, Y. Kitamura, D. Tsuchiya, 2004 .

Heat shock protein-90-induced microglial clearance of exogenous amyloid-β1–42 in rat hippocampus in vivo

K. Takata, Y. Kitamura, D. Tsuchiya, 2003, Neuroscience Letters.

Possible Involvement of Small Oligomers of Amyloid-β Peptides in 15-Deoxy-Δ12,14 Prostaglandin J2-Sensitive Microglial Activation

P. Gebicke-haerter, K. Takata, Y. Kitamura, 2003 .

Involvement of Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE) and Rac1 in the phagocytosis of amyloid-beta(1-42) in rat microglia.

P. Gebicke-haerter, K. Takata, Y. Kitamura, 2003, Journal of pharmacological sciences.

Possible Protective Mechanisms of Heme Oxygenase‐1 in the Brain

M. Smith, P. Gebicke-haerter, K. Takata, 2002, Annals of the New York Academy of Sciences.

Microglial transplantation increases amyloid-beta clearance in Alzheimer model rats.

K. Takata, Y. Kitamura, D. Yanagisawa, 2007, FEBS letters.

Temporal changes of CD68 and α7 nicotinic acetylcholine receptor expression in microglia in Alzheimer's disease-like mouse models.

K. Takata, Y. Kitamura, S. Shimohama, 2015, Journal of Alzheimer's disease : JAD.

Role of high mobility group protein-1 (HMG1) in amyloid-β homeostasis

K. Takata, Y. Kitamura, D. Tsuchiya, 2003 .

Galantamine-induced Amyloid-β Clearance Mediated via Stimulation of Microglial Nicotinic Acetylcholine Receptors*

K. Takata, Y. Kitamura, Mana Saeki, 2010, The Journal of Biological Chemistry.

Developmental expression of neural Wiskott–Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE)-related proteins in postnatal rat cerebral cortex and hippocampus

K. Takata, Y. Kitamura, D. Tsuchiya, 2006, Neuroscience Research.

Daphnetin inhibits invasion and migration of LM8 murine osteosarcoma cells by decreasing RhoA and Cdc42 expression.

K. Takata, H. Murata, K. Itoh, 2016, Biochemical and biophysical research communications.

Generation of striatal neurons from human induced pluripotent stem cells by controlling extrinsic signals with small molecules.

K. Takata, S. Shimohama, K. Nishimura, 2021, Stem cell research.

Kainic acid-induced inducible cyclooxygenase and c-Jun phosphorylation in the rat hippocampal formation

H. Kimura, K. Takata, Y. Kitamura, 1999, Brain Research.

Accelerative effects of carbazole-type alkaloids from Murraya koenigii on neurite outgrowth and their derivative’s in vivo study for spatial memory

K. Takata, H. Matsuda, K. Nishimura, 2020, Journal of Natural Medicines.

Parkinsonian rotenone mouse model: reevaluation of long-term administration of rotenone in C57BL/6 mice.

K. Takata, Y. Kitamura, T. Taniguchi, 2011, Biological & pharmaceutical bulletin.

High mobility group box protein-1 inhibits microglial Abeta clearance and enhances Abeta neurotoxicity.

K. Takata, Y. Kitamura, D. Tsuchiya, 2004, Journal of neuroscience research.

Effect of selective serotonin reuptake inhibitors via 5-HT1A receptors on L-DOPA-induced rotational behavior in a hemiparkinsonian rat model.

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Journal of pharmacological sciences.

Neuroprotective function in brain microglia

K. Takata, Y. Kitamura, D. Yanagisawa, 2009 .

Microglia-Like Monocytic Cells Derived From Bone Marrow Cells Phagocytose Amyloid-β and Facilitate Phagocytosis Of Amyloid-β By Resident Microglia

K. Takata, E. Ashihara, Shohei Kawanishi, 2013 .

3‐[(2,4‐dimethoxy)benzylidene]‐anabaseine dihydrochloride protects against 6‐hydroxydopamine‐induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats

K. Takata, Y. Kitamura, S. Shimohama, 2013, Journal of neuroscience research.

Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone‐treated parkinsonian mice

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Journal of neuroscience research.

Clearance of amyloid-β in microglial culture model

K. Takata, Y. Kitamura, D. Tsuchiya, 2004 .

Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.

K. Takata, Y. Kitamura, T. Taniguchi, 2011, Journal of pharmacological sciences.

α-Synuclein protein is not scavenged in neuronal loss induced by kainic acid or focal ischemia

K. Takata, Y. Kitamura, T. Taniguchi, 2001, Brain Research.

Serofendic acid prevents 6‐hydroxydopamine‐induced nigral neurodegeneration and drug‐induced rotational asymmetry in hemi‐parkinsonian rats

K. Takata, Y. Kitamura, D. Yanagisawa, 2005, Journal of neurochemistry.

Distribution of DJ-1, Parkinson's disease-related protein PARK7, and its alteration in 6-hydroxydopamine-treated hemiparkinsonian rat brain.

Kazuyuki Takata, Takashi Yanagida, Hiroyoshi Ariga, 2006, Journal of pharmacological sciences.

MEK/ERK Signaling Regulates Reconstitution of the Dopaminergic Nerve Circuit in the Planarian Dugesia japonica

K. Takata, Y. Kitamura, K. Fukao, 2021, Neurochemical Research.

Pharmacological assessment of methamphetamine-induced behavioral hyperactivity mediated by dopaminergic transmission in planarian Dugesia japonica.

K. Yoshimoto, K. Takata, Y. Kitamura, 2014, Biochemical and biophysical research communications.

DJ-1 Protects against Neurodegeneration Caused by Focal Cerebral Ischemia and Reperfusion in Rats

K. Takata, Y. Kitamura, D. Yanagisawa, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Mumefural prevents insulin resistance and amyloid-beta accumulation in the brain by improving lowered interstitial fluid pH in type 2 diabetes mellitus.

Y. Tsubo, K. Takata, T. Nakahari, 2023, Biomedical research.

Oxidative Neurodegeneration Is Prevented by UCP0045037, an Allosteric Modulator for the Reduced Form of DJ-1, a Wild-Type of Familial Parkinson’s Disease-Linked PARK7

K. Takata, Y. Kitamura, D. Yanagisawa, 2009, International journal of molecular sciences.

Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Neuroscience Research.

Inhibitory effects of antiparkinsonian drugs and caspase inhibitors in a parkinsonian flatworm model.

K. Takata, Y. Kitamura, T. Taniguchi, 2003, Journal of pharmacological sciences.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

F. Ginhoux, Steffen Jung, Jinqiu Zhang, 2020, Immunity.

Increase of Bcl-2 protein in neuronal dendritic processes of cerebral cortex and hippocampus by the antiparkinsonian drugs, talipexole and pramipexole

K. Takata, Y. Kitamura, T. Taniguchi, 2000, Brain Research.

Inhibition of monocarboxylate transporter 1 suppresses the proliferation of glioblastoma stem cells

K. Takata, E. Ashihara, T. Takada, 2016, The Journal of Physiological Sciences.

Expression and role of nicotinic acetylcholine receptors during midbrain dopaminergic neuron differentiation from human induced pluripotent stem cells

K. Takata, S. Shimohama, Kaneyasu Nishimura, 2023, Neuropsychopharmacology reports.

Neuroprotective effects of 5-aminolevulinic acid against neurodegeneration in rat models of Parkinson's disease and stroke.

K. Takata, Y. Kitamura, D. Yanagisawa, 2020, Journal of Pharmacological Sciences.

K. Takata, Y. Kitamura, S. Shimohama, 2013, Journal of neuroscience research.

Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Neuroscience Research.

Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

K. Takata, Y. Kitamura, S. Morikawa, 2009, Oxidative medicine and cellular longevity.

Effects of a DJ-1-Binding Compound on Spatial Learning and Memory Impairment in a Mouse Model of Alzheimer's Disease.

K. Takata, Y. Kitamura, S. Shimohama, 2016, Journal of Alzheimer's disease : JAD.