D. Mercola

D. Mercola, R. Gjerset, S. Turla, 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Analysis of a transformed cell line using antisense c-fos RNA.

D. Mercola, J. Westwick, E. Adamson, 1988, Gene.

A Gradient Boosting Algorithm for Survival Analysis via Direct Optimization of Concordance Index

Xiaohui Xie, Yifei Chen, Zhenyu Jia, 2013, Comput. Math. Methods Medicine.

Calcium-dependent distance changes in binary and ternary complexes of troponin.

D. Mercola, A. Wollmer, J. Fleischhauer, 1990, European journal of biochemistry.

Interaction of troponin subunits. The interaction between the inhibitory and tropomyosin-binding subunits.

D. Mercola, J. Horwitz, B. Bullard, 1979, Journal of Biological Chemistry.

Comparison of the calcium- and magnesium-induced structural changes of troponin--C. A proton magnetic resonance study.

J. Thornton, D. Mercola, B. Levine, 1978, Biochimica et biophysica acta.

Direct identification of the high and low affinity calcium binding sites of troponin-C.

D. Mercola, I. L. Sin, R. Fernandes, 1978, Biochemical and biophysical research communications.

Identification of Biomarkers for Prostate Cancer Prognosis Using a Novel Two-Step Cluster Analysis

Xin Chen, Shizhong Xu, Yipeng Wang, 2011, PRIB.

Wnt signaling in castration-resistant prostate cancer: implications for therapy.

D. Mercola, N. Yokoyama, X. Zi, 2014, American journal of clinical and experimental urology.

In Vivo Cloning and Characterization of a New Growth Suppressor Protein TOE1 as a Direct Target Gene of Egr1*

D. Mercola, E. Adamson, I. de Belle, 2003, The Journal of Biological Chemistry.

C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma.

J. Rhim, D. Mercola, F. Bost, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Generation of “Virtual” Control Groups for Single Arm Prostate Cancer Adjuvant Trials

T. Ahlering, J. Wang-Rodriguez, Z. Jia, 2014, PloS one.

An Accurate Prostate Cancer Prognosticator Using a Seven-Gene Signature Plus Gleason Score and Taking Cell Type Heterogeneity into Account

Shizhong Xu, Z. Jia, Anne Sawyers, 2012, PloS one.

Prostate Cancer Postoperative Nomogram Scores and Obesity

M. Kattan, J. Pierce, C. Macera, 2011, PloS one.

Early Growth Response 3 (Egr3) Is Highly Over-Expressed in Non-Relapsing Prostate Cancer but Not in Relapsing Prostate Cancer

Z. Jia, D. Mercola, V. Baron, 2013, PloS one.

The Transcription Factor EGR-1 Directly Transactivates the Fibronectin Gene and Enhances Attachment of Human Glioblastoma Cell Line U251*

D. Mercola, E. Adamson, J Yao, 2000, The Journal of Biological Chemistry.

Essential Role of p38γ in K-Ras Transformation Independent of Phosphorylation*

Jiahuai Han, D. Mercola, Jun Tang, 2005, Journal of Biological Chemistry.

Survey of differentially methylated promoters in prostate cancer cell lines.

Michael McClelland, Dan Mercola, Gaelle Rondeau, 2005, Neoplasia.

Egr1 Signaling in Prostate Cancer

D. Mercola, E. Adamson, I. Belle, 2003, Cancer biology & therapy.

Novel Array-Based Target Identification for Synergistic Sensitization of Breast Cancer to Herceptin

D. Mercola, 2010 .

The Activation of c-Jun NH2-terminal Kinase (JNK) by DNA-damaging Agents Serves to Promote Drug Resistance via Activating Transcription Factor 2 (ATF2)-dependent Enhanced DNA Repair*

D. Mercola, J. Hayakawa, M. Ohmichi, 2003, Journal of Biological Chemistry.

Inhibition of Extracellular Signal-regulated Protein Kinase or c-Jun N-terminal Protein Kinase Cascade, Differentially Activated by Cisplatin, Sensitizes Human Ovarian Cancer Cell Line*

D. Mercola, J. Hayakawa, M. Ohmichi, 1999, The Journal of Biological Chemistry.

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

M. Karin, D. Mercola, M. Birrer, 1991, Nature.

Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset

Vanessa M. Scarfone, D. Mercola, A. Agrawal, 2019, The journals of gerontology. Series A, Biological sciences and medical sciences.

Tumor Microenvironment: Prospects for Diagnosis and Prognosis of Prostate Cancer Based on Changes in Tumor-Adjacent Stroma

Z. Jia, D. Mercola, Chung Lee, 2018 .

Plasma-Derived Exosomal Survivin, a Plausible Biomarker for Early Detection of Prostate Cancer

Dan Mercola, Saied Mirshahidi, D. Mercola, 2012, PloS one.

TGF-β mediated DNA methylation in prostate cancer

M. Soares, Z. Jia, D. Mercola, 2012, Translational andrology and urology.

Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy.

D. Mercola, K. Black, H. Lin, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Egr1 Transcription Factor: Multiple Roles in Prostate Tumor Cell Growth and Survival

D. Mercola, E. Adamson, 2002, Tumor Biology.

Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry

Z. Jia, Patricia D. Castro, M. Ittmann, 2021, Cancers.

Expression profile of human gingival fibroblasts induced by interleukin-1beta reveals central role of nuclear factor-kappa B in stabilizing human gingival fibroblasts during inflammation.

D. Mercola, Shilpi Arora, S. Vardar-Sengul, 2009, Journal of periodontology.

Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention.

D. Mercola, P. Sassone-Corsi, Yan-Bing Zhang, 2013, Current cancer drug targets.

Use of wild‐type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53

D. Mercola, P. Hopkins, R. Gjerset, 1995, Molecular carcinogenesis.

Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model

D. Mercola, M. Lilly, N. Yokoyama, 2015, Oncotarget.

The proto-oncogene c-fos is over-expressed in the majority of human osteosarcomas.

D. Mercola, J. Morris, H. Niman, 1990, Oncogene.

When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?

D. Mercola, N. Yokoyama, E. Uchio, 2015, Current Pharmacology Reports.

Reciprocal modulation between Sp1 and Egr‐1

Ruo-Pan Huang, D. Mercola, Yan Fan, 1997, Journal of cellular biochemistry.

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells

T. Mustelin, D. Mercola, E. Adamson, 2007, Cell Death and Differentiation.

Atomic Positions in Rhombohedral 2-Zinc Insulin Crystals

T. Blundell, D. Mercola, D. Hodgkin, 1971, Nature.

Calcium binding by troponin-C and homologs is correlated with the position and linear density of "beta-turn forming" residues.

D. Mercola, A. Wollmer, B. Bullard, 1979, Journal of theoretical biology.

Inhibition of Growth Factor Stimulated Pathways for the Treatment of Prostate Cancer

O. Potapova, M. Pfahl, D. Mercola, 2002 .

Three-Dimensional Atomic Structure of Insulin and Its Relationship to Activity

T. Blundell, D. Mercola, D. Hodgkin, 1972, Diabetes.

Structure of insulin in 4-zinc insulin

D. Mercola, D. Hodgkin, E. Dodson, 1976, Nature.

Identification of a CD28 Response Element in the CD40 Ligand Promoter1

T. Mustelin, D. Mercola, E. Parra, 2001, The Journal of Immunology.

Antisense to the Early Growth Response‐1 Gene (Egr‐1) Inhibits Prostate Tumor Development in TRAMP Mice

J. Rhim, D. Mercola, V. Baron, 2003, Annals of the New York Academy of Sciences.

Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation

D. Mercola, G. Burgess, H. Boswell, 2002, Leukemia.

Egr1 Promotes Growth and Survival of Prostate Cancer Cells

D. Mercola, T. Virolle, E. Adamson, 2003, The Journal of Biological Chemistry.

Egr 1 promotes growth and survival of prostate cancer cells : identification of novel Egr 1 target genes

D. Mercola, T. Virolle, E. Adamson, 2003 .

Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.

Dan Mercola, D. Mercola, E. Adamson, 2005, Cancer research.

Early Growth Response 1 Acts as a Tumor Suppressor In vivo and In vitro via Regulation of p 53

D. Mercola, E. Adamson, S. Mittal, 2005 .

Early Growth Response 3 regulates genes of inflammation and directly activates IL6 and IL8 expression in prostate cancer

Z. Jia, D. Mercola, V. Baron, 2015, British Journal of Cancer.

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases

James L. Mohler, Elaine A. Ostrander, Timothy R. Rebbeck, 2015, Human Genetics.

RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans

D. Mercola, F. Rahmatpanah, M. Lilly, 2021, Oncotarget.

Transcriptome Analysis of Ovarian and Uterine Clear Cell Malignancies

D. Mercola, A. Agrawal, F. Rahmatpanah, 2020, Frontiers in Oncology.

The identification of trans-associations between prostate cancer GWAS SNPs and RNA expression differences in tumor-adjacent stroma

J. Trent, D. Duggan, Z. Jia, 2015, Oncotarget.

the Expression Phenotype of SNPs Linked to the Risk for Prostate Cancer

Z. Jia, D. Mercola, F. Rahmatpanah, 2014 .

Correction: Expression Changes in the Stroma of Prostate Cancer Predict Subsequent Relapse

Z. Jia, Yipeng Wang, Anne Sawyers, 2012, PLoS ONE.

Suppression of growth and transformation and induction of apoptosis by EGR-1.

V. Rangnekar, D. Mercola, E. Adamson, 1998, Cancer gene therapy.

Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence

Dan Mercola, D. Mercola, E. Adamson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Messenger RNAs under Differential Translational Control in Ki-ras–Transformed Cells

Michael McClelland, Brendan M Duggan, Dan Mercola, 2006, Molecular Cancer Research.

The early growth response gene EGR-1 behaves as a suppressor gene that is down-regulated independent of ARF/Mdm2 but not p53 alterations in fresh human gliomas.

A. Porcellini, D. Mercola, G. Giannini, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Expression differences between African American and Caucasian prostate cancer tissue reveals that stroma is the site of aggressive changes

Zhenyu Jia, Jessica Wang-Rodriguez, Dan Mercola, 2014, International journal of cancer.

Expression between African American and Caucasian Prostate Cancer Tissue Reveals that Stroma is the Site of Aggressive Changes

J. Wang-Rodriguez, Z. Jia, Anne Sawyers, 2013 .

Inhibition of Egr-1 expression reverses transformation of prostate cancer cells in vitro and in vivo

D. Mercola, T. Virolle, V. Baron, 2003, Oncogene.

The Early Growth Response Gene EGR-1 Behaves as a Suppressor Gene That Is Down-Regulated Independent of ARF / Mdm 2 but not p 53 Alterations in Fresh Human Gliomas 1

A. Porcellini, D. Mercola, G. Giannini, 2001 .

The wisdom of the commons: ensemble tree classifiers for prostate cancer prognosis

Yipeng Wang, Zhenyu Jia, Michael McClelland, 2009, Bioinform..

Expression of HER2 in Breast Cancer Promotes a Massive Reorganization of Gene Activity and Suggests a Role for Epigenetic Regulation.

Z. Jia, D. Mercola, F. Rahmatpanah, 2012, Journal of data mining in genomics & proteomics.

Assessing Researcher Needs for a Virtual Biobank.

Dan Mercola, Brian Gardner, Sarah Dry, 2017, Biopreservation and biobanking.

Characterization of a new human glioblastoma cell line that expresses mutant P53 and lacks activation of the PDGF pathway

D. Mercola, S. Wen, Hong Lin, 1995, In Vitro Cellular & Developmental Biology - Animal.

Transformation-specific pattern of phosphorylation of c-Jun, Jun-B, Jun-D and Egr-1 in v-sis transformed cells.

D. Mercola, E. Adamson, A. Grover-Bardwick, 1994, Carcinogenesis.

Use of resonance interaction in the study of the chain folding of insulin in solution.

D. Mercola, E. Arquilla, J. Morris, 1972, Biochemistry.

Six stroma-based RNA markers diagnostic for prostate cancer in European-Americans validated at the RNA and protein levels in patients in China

Z. Jia, D. Mercola, W. Zhong, 2015, Oncotarget.

Reversible transformation by v-sis: a model cell line for analysis of transformation by antisense methods.

D. Mercola, M. Mercola, P. Carpenter, 1991, Antisense research and development.

Calculated tyrosyl circular dichroism of proteins

T. Blundell, D. Mercola, J. Pitts, 1982, FEBS letters.

Claudin‐1 immunohistochemistry for distinguishing malignant from benign epithelial lesions of prostate

John Calvin Reed, S. Krajewski, M. Krajewska, 2007, The Prostate.

Genes in Stroma Diagnosis of Prostate Cancer Using Differentially Expressed

J. Wang-Rodriguez, Qiang Xu, Z. Jia, 2011 .

The structure and biology of insulin.

D. Mercola, D. Hodgkin, E. Dodson, 1971, The Biochemical journal.

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells

T. Mustelin, D. Mercola, E. Adamson, 2007, Cell Death and Differentiation.

Bcl-B Expression in Human Epithelial and Nonepithelial Malignancies

J. Winter, M. Duffy, John Calvin Reed, 2008, Clinical Cancer Research.

The cloning debates and progress in biotechnology.

D. Mercola, P. Wolf, G. Liggins, 1997, Clinical chemistry.

The combination of inhibition of RNA degradation and comparative genomic scanning is a powerful new method for detecting gene disruptions. The utility of the method is well-illustrated by a series of observations linking the ephrin receptor EPHB2 to prostate cancer.

J. Welsh, D. Mercola, 2004 .

Gene therapy approaches to sensitization of human prostate carcinoma to cisplatin by adenoviral expression of p53 and by antisense jun kinase oligonucleotide methods.

D. Mercola, R. Gjerset, S. Lebedeva, 2001, Methods in molecular biology.

The JUN Kinase/Stress-activated Protein Kinase Pathway Is Required for Epidermal Growth Factor Stimulation of Growth of Human A549 Lung Carcinoma Cells*

D. Mercola, F. Bost, R. Mckay, 1997, The Journal of Biological Chemistry.

The crystal structure of rhombohedral 2 zinc insulin.

T. Blundell, D. Mercola, D. Hodgkin, 1972, Cold Spring Harbor symposia on quantitative biology.

Six stroma-based RNA markers diagnostic for prostate cancer in European-Americans validated at the RNA and protein levels in patients in China

Z. Jia, D. Mercola, W. Zhong, 2015, Oncotarget.

The identification of trans-associations between prostate cancer GWAS SNPs and RNA expression differences in tumor-adjacent stroma

J. Trent, D. Duggan, Z. Jia, 2015, Oncotarget.

Cancer Cell International Inhibition of Cell Growth by Egr-1 in Human Primary Cultures from Malignant Glioma

A. Porcellini, D. Mercola, L. Frati, 2022 .

Overexpression of Periostin in Stroma Positively Associated with Aggressive Prostate Cancer

Yuan Tian, Hui Zhang, D. Chia, 2015, PloS one.

c-Jun N-terminal Kinase Is Essential for Growth of Human T 98 G Glioblastoma Cells *

M. Gorospe, N. Holbrook, O. Potapova, 2000 .