I. Zuhorn

发表

Robust formation of biodegradable polymersomes by direct hydration

X. Sui, P. Kujala, G. Janssen, 2015 .

Aliphatic Quaternary Ammonium Functionalized Nanogels for Gene Delivery

I. Zuhorn, D. Keskin, Huaiying Zhang, 2021, Pharmaceutics.

Carriers Break Barriers in Drug Delivery: Endocytosis and Endosomal Escape of Gene Delivery Vectors

Z. Rehman, I. Zuhorn, Isabelle M S Degors, 2019, Accounts of chemical research.

Mechanism of polyplex- and lipoplex-mediated delivery of nucleic acids: real-time visualization of transient membrane destabilization without endosomal lysis.

I. Zuhorn, D. Hoekstra, Zia ur Rehman, 2013, ACS nano.

Nonviral gene delivery vectors use syndecan-dependent transport mechanisms in filopodia to reach the cell surface.

I. Zuhorn, J. Kuipers, D. Hoekstra, 2012, ACS nano.

Protein kinase A inhibition modulates the intracellular routing of gene delivery vehicles in HeLa cells, leading to productive transfection.

I. Zuhorn, D. Hoekstra, Zia ur Rehman, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Gene delivery by cationic lipid vectors: overcoming cellular barriers

I. Zuhorn, D. Hoekstra, J. Engberts, 2007, European Biophysics Journal.

Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis.

I. Zuhorn, V. Oberle, D. Hoekstra, 2004, The Biochemical journal.

Lipoplex-mediated Transfection of Mammalian Cells Occurs through the Cholesterol-dependent Clathrin-mediated Pathway of Endocytosis*

I. Zuhorn, D. Hoekstra, R. Kalicharan, 2002, The Journal of Biological Chemistry.

Cationic amphiphiles as delivery system for genes into eukaryotic cells

I. Zuhorn, V. Oberle, D. Hoekstra, 2000 .

Ultrasound and Microbubble-Targeted Delivery of Macromolecules Is Regulated by Induction of Endocytosis and Pore Formation

Nico de Jong, Otto Kamp, Marcia Emmer, 2009, Circulation research.

Induction of Endocytosis and Pore Formation Ultrasound and Microbubble-Targeted Delivery of Macromolecules Is Regulated

W. Paulus, O. Kamp, N. Jong, 2009 .

Gene delivery by cationic lipids: in and out of an endosome.

I. Zuhorn, D. Hoekstra, J. Rejman, 2007, Biochemical Society transactions.

Imaging of Cells and Nanoparticles: Implications for Drug Delivery to the Brain

I. Zuhorn, Katica Stojanov, R. Dierckx, 2012, Pharmaceutical Research.

Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro.

I. Zuhorn, P. Couraud, D. Hoekstra, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Correlating Corona Composition and Cell Uptake to Identify Proteins Affecting Nanoparticle Entry into Endothelial Cells

I. Zuhorn, A. Salvati, Reinier Bron, 2021, ACS biomaterials science & engineering.

Disentangling Biomolecular Corona Interactions With Cell Receptors and Implications for Targeting of Nanomedicines

I. Zuhorn, A. Salvati, Aldy Aliyandi, 2020, Frontiers in Bioengineering and Biotechnology.

Size dependent biodistribution and SPECT imaging of (111)In-labeled polymersomes.

I. Zuhorn, J. V. van Hest, F. Rutjes, 2012, Bioconjugate chemistry.

Solid lipid nanoparticles for cancer therapy

I. Zuhorn, D. Hoekstra, M. Bispo, 2015 .

Solid lipid nanoparticles as nucleic acid delivery system: properties and molecular mechanisms.

I. Zuhorn, M. D. de Jesus, Inge S Zuhorn, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration

J. D. Arias-Londoño, I. Zuhorn, G. P. Cardona-Gómez, 2020, Frontiers in Aging Neuroscience.

Targeting TNFR2 as a Novel Therapeutic Strategy for Alzheimer’s Disease

I. Zuhorn, P. Naudé, P. Deyn, 2019, Front. Neurosci..

University of Groningen Targeting TNFR 2 as a novel therapeutic strategy for Alzheimer ' s disease

I. Zuhorn, P. Naudé, P. Deyn, 2019 .

University of Groningen Adhesion Receptors Mediate Efficient Non-viral Gene Delivery

G. Robillard, I. Zuhorn, D. Hoekstra, 2007 .

Adhesion receptors mediate efficient non-viral gene delivery.

G. Robillard, I. Zuhorn, D. Hoekstra, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Chapter 7 In vivo biodistribution of prion-and GM 1-targeted polymersomes following intravenous administration in mice

I. Zuhorn, F. Rutjes, Katica Stojanov, 2012 .

In vivo biodistribution of prion- and GM1-targeted polymersomes following intravenous administration in mice.

I. Zuhorn, J. V. van Hest, F. Rutjes, 2012, Molecular pharmaceutics.

Endocytosis of Extracellular Vesicles and Release of Their Cargo from Endosomes

B. Giepmans, I. Zuhorn, Marit A. de Beer, 2020, ACS nano.

Labeling of C17.2 neural stem cells with PET- and SPECT-radiotracers and in vivo imaging in rats

I. Zuhorn, D. Hoekstra, Katica Stojanov, 2012 .

Chapter 3 Labeling of C 17 . 2 neural stem cells with PET-and SPECT-radiotracers and in vivo imaging in rats

I. Zuhorn, D. Hoekstra, Katica Stojanov, 2012 .

Heparan sulfate proteoglycan‐mediated dynamin‐dependent transport of neural stem cell exosomes in an in vitro blood–brain barrier model

I. Zuhorn, Bhagyashree S. Joshi, B. Joshi, 2020, The European journal of neuroscience.

Neural stem cell plasma membrane vesicles as effective nanocarriers for drug delivery into the brain

I. Zuhorn, D. Hoekstra, Katica Stojanov, 2012 .

Lipoplex formation under equilibrium conditions reveals a three-step mechanism.

I. Zuhorn, V. Oberle, D. Hoekstra, 2000, Biophysical journal.

Interference of serum with lipoplex-cell interaction: modulation of intracellular processing.

I. Zuhorn, D. Hoekstra, U. Bakowsky, 2002, Biochimica et biophysica acta.

Development of curcumin-loaded zein nanoparticles for transport across the blood-brain barrier and inhibition of glioblastoma cell growth.

I. Zuhorn, Reinier Bron, A. Kros, 2021, Biomaterials science.

Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency.

I. Zuhorn, V. Oberle, D. Hoekstra, 2002, Biophysical journal.

Inclusion of the helper lipid dioleoyl-phosphatidylethanolamine in solid lipid nanoparticles inhibits their transfection efficiency.

I. Zuhorn, M. D. de Jesus, D. Hoekstra, 2014, Journal of biomedical nanotechnology.

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation

D. Arango, I. Zuhorn, J. Kuipers, 2019, PLoS biology.

Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug Delivery

I. Zuhorn, W. Baron, Pauline E. M. van Schaik, 2022, International journal of molecular sciences.

A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model

I. Zuhorn, H. Wajant, P. Naudé, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Influence of diamond crystal orientation on the interaction with biological matter

I. Zuhorn, D. Vanpoucke, R. Schirhagl, 2020, Carbon.

Entry of PIP3-containing polyplexes into MDCK epithelial cells by local apical-basal polarity reversal

I. Zuhorn, Cuifeng Wang, K. Sjollema, 2016, Scientific Reports.

CD146 increases stemness and aggressiveness in glioblastoma and activates YAP signaling

I. Zuhorn, W. D. den Dunnen, J. Paridaen, 2022, Cellular and Molecular Life Sciences.

Design of solid lipid nanoparticles for gene delivery into prostate cancer.

I. Zuhorn, M. D. de Jesus, D. Hoekstra, 2010, Journal of controlled release : official journal of the Controlled Release Society.

DNAJB6-Containing Extracellular Vesicles as Chaperone Delivery Systems: A Proteomic Analysis

I. Zuhorn, M. D. de Vries, Aldy Aliyandi, 2022, Pharmaceutics.

Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency.

Evgeny Polushkin, Udo Bakowsky, I. Zuhorn, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Converting Extracellular Vesicles into Nanomedicine: Loading and Unloading of Cargo

I. Zuhorn, Bhagyashree S. Joshi, Daniel Ortiz, 2021, Materials Today Nano.

The Future of Nanotechnology: Cross-disciplined Progress to Improve Health and Medicine.

Warren Chan, Jinwoo Cheon, Inge Zuhorn, 2019, Accounts of chemical research.

[18F]FDG Labeling of Neural Stem Cells for in Vivo Cell Tracking with Positron Emission Tomography: Inhibition of Tracer Release by Phloretin

A. van Waarde, I. Zuhorn, D. Hoekstra, 2012, Molecular imaging.

Extracellular Vesicles and Circulating Nucleic Acids

Akers, D. Steindler, H. Sultana, 2021 .

How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances.

Z. Rehman, I. Zuhorn, D. Hoekstra, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Peptide-mediated blood-brain barrier transport of polymersomes.

I. Zuhorn, J. V. van Hest, F. Rutjes, 2012, Angewandte Chemie.

Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier

I. Zuhorn, D. Hoekstra, Dick Hoekstra, 2014, Pharmaceutics.

Targeting TNFR2 as a Novel Therapeutic Strategy for Alzheimer’s Disease

I. Zuhorn, P. Naudé, U. Eisel, 2019, Front. Neurosci..

Microemulsion extrusion technique: a new method to produce lipid nanoparticles

I. Zuhorn, A. Radaic, E. Paula, 2013, Journal of Nanoparticle Research.

Light-induced molecular rotation triggers on-demand release from liposomes.

B. Feringa, I. Zuhorn, Qihui Zhou, 2020, Chemical communications.

Effect of endothelial cell heterogeneity on nanoparticle uptake.

B. Bartosch, I. Zuhorn, A. Salvati, 2020, International journal of pharmaceutics.

A sensor for quantification of macromolecular crowding in living cells

Arnold J. Boersma, Bert Poolman, A. Boersma, 2015, Nature Methods.

On the application of scanning force microscopy in (cell) biology

I. Zuhorn, V. Oberle, D. Hoekstra, 2002 .

On the Mechanism of Cationic Amphiphile-mediated Transfection. To Fuse or not to Fuse: Is that the Question?

I. Zuhorn, D. Hoekstra, I. S. Zuhorn, 2002, The Journal of Membrane Biology.

LOW NANOGEL STIFFNESS FAVORS NANOGEL TRANSCYTOSIS ACROSS AN IN VITRO BLOOD-BRAIN BARRIER.

I. Zuhorn, D. Keskin, Guangyue Zu, 2021, Nanomedicine : nanotechnology, biology, and medicine.

DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease

H. Kampinga, I. Zuhorn, Reinier Bron, 2021, iScience.

A filter‐free blood‐brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

Loai K. E. A. Abdelmohsen, David S. Williams, I. Zuhorn, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Ultrasound and Microbubble-Targeted Delivery of Macromolecules Is Regulated by Induction of Endocytosis and Pore Formation

W. Paulus, O. Kamp, R. Henning, 2009, Circulation research.

Imaging of Cells and Nanoparticles: Implications for Drug Delivery to the Brain

I. Zuhorn, Katica Stojanov, R. Dierckx, 2012, Pharmaceutical Research.

Modulation of membrane traffic by mechanical stimuli

M. Emmer, Vimalkumar A. Patel, W. Paulus, 2001 .

Nanobiomaterials for biological barrier crossing and controlled drug delivery

B. Feringa, I. Zuhorn, P. Rijn, 2022 .

[18F]FDG Labeling of Neural Stem Cells for in Vivo Cell Tracking with Positron Emission Tomography: Inhibition of Tracer Release by Phloretin

A. van Waarde, I. Zuhorn, D. Hoekstra, 2012, Molecular imaging.

Size dependent biodistribution and SPECT imaging of (111)In-labeled polymersomes.

I. Zuhorn, J. V. van Hest, F. Rutjes, 2012, Bioconjugate chemistry.

Breaking free: endocytosis and endosomal escape of extracellular vesicles

I. Zuhorn, L. Ribovski, B. Joshi, 2023, Extracellular Vesicles and Circulating Nucleic Acids.