M. Nakagawa

发表

Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C.

M. Kurosaki, N. Hiramatsu, M. Sakamoto, 2012, Journal of hepatology.

Hepatitis C virus NS4B protein targets STING and abrogates RIG‐I–mediated type I interferon‐dependent innate immunity

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2013, Hepatology.

Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated‐interferon plus ribavirin therapy for chronic hepatitis C

N. Enomoto, M. Kurosaki, M. Sakamoto, 2013, Journal of medical virology.

Age and Total Ribavirin Dose are Independent Predictors of Relapse after Interferon Therapy in Chronic Hepatitis C Revealed by Data Mining Analysis

M. Kurosaki, N. Hiramatsu, M. Sakamoto, 2012, Antiviral therapy.

Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha.

N. Enomoto, M. Kurosaki, S. Kakinuma, 2004, The Journal of infectious diseases.

A case of hepatitis C virus-associated mixed cryoglobulinemia treated with direct-acting antivirals

S. Kakinuma, M. Nakagawa, Y. Asahina, 2016 .

Analysis of the Complete Open Reading Frame of Genotype 2b Hepatitis C Virus in Association with the Response to Peginterferon and Ribavirin Therapy

N. Enomoto, M. Sakamoto, N. Sakamoto, 2011, PloS one.

Analysis of the complete open reading frame of hepatitis C virus in genotype 2a infection reveals critical sites influencing the response to peginterferon and ribavirin therapy

N. Enomoto, M. Sakamoto, N. Sakamoto, 2011, Hepatology international.

Serum Interleukin-6 Levels Correlate with Resistance to Treatment of Chronic Hepatitis C Infection with Pegylated-Interferon-α2B plus Ribavirin

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2011, Antiviral therapy.

ITPA gene variant protects against anemia induced by pegylated interferon‐α and ribavirin therapy for Japanese patients with chronic hepatitis C

N. Enomoto, M. Honda, S. Kakinuma, 2010, Hepatology research : the official journal of the Japan Society of Hepatology.

Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection

N. Enomoto, S. Kakinuma, N. Sakamoto, 2010, Journal of Gastroenterology.

Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins.

N. Enomoto, S. Kakinuma, N. Sakamoto, 2005, Gastroenterology.

Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium.

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2019, Journal of hepatology.

Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity.

N. Enomoto, N. Sakamoto, M. Nakagawa, 2008, Virology.

Association of serum interferon‐λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct‐acting antiviral agents

S. Kakinuma, M. Nakagawa, M. Mizokami, 2019, Hepatology research : the official journal of the Japan Society of Hepatology.

α‐fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C

N. Enomoto, M. Kurosaki, S. Kakinuma, 2013, Hepatology.

Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features

N. Enomoto, M. Sakamoto, S. Kakinuma, 2016, Journal of Gastroenterology.

ITPA gene variation and ribavirin‐induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin

S. Kakinuma, M. Nakagawa, Y. Asahina, 2017, Hepatology research : the official journal of the Japan Society of Hepatology.

Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients

S. Kakinuma, M. Nakagawa, Y. Asahina, 2019, Scientific Reports.

Association of ITPA gene variation and serum ribavirin concentration with a decline in blood cell concentrations during pegylated interferon-alpha plus ribavirin therapy for chronic hepatitis C

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2013, Hepatology International.

Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C

H. Nomura, H. Yoshiji, N. Enomoto, 2014, Human Genetics.

Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice

H. Nakauchi, S. Kakinuma, N. Sakamoto, 2013, Hepatology.

Polymorphism Near the Interleukin-28B Gene and Anti-Hepatitis C Viral Response

S. Kakinuma, M. Nakagawa, Y. Asahina, 2013, Journal of clinical and translational hepatology.

Inhibition of Hepatitis C Virus Replication by a Specific Inhibitor of Serine-Arginine-Rich Protein Kinase

M. Hagiwara, S. Kakinuma, N. Sakamoto, 2010, Antimicrobial Agents and Chemotherapy.

Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2019, Hepatology Communications.

Two flavonoids extracts from Glycyrrhizae radix inhibit in vitro hepatitis C virus replication

N. Enomoto, N. Sakamoto, M. Nakagawa, 2009, Hepatology research : the official journal of the Japan Society of Hepatology.

Utility of microcrystalline cellulose to prevent drug segregation in direct powder compression

M. Nakagawa, Takatoshi Sakamoto, H. Yuasa, 2019, Journal of Drug Delivery Science and Technology.

Association of IL28B variants with response to pegylated‐interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b

M. Kurosaki, A. Tamori, S. Kakinuma, 2011, Journal of medical virology.

Impaired induction of interleukin 28B and expression of interferon λ 4 associated with nonresponse to interferon‐based therapy in chronic hepatitis C

S. Kakinuma, M. Nakagawa, Y. Asahina, 2015, Journal of gastroenterology and hepatology.

Effect of interferon-based and -free therapy on early occurrence and recurrence of hepatocellular carcinoma in chronic hepatitis C.

S. Kakinuma, M. Nakagawa, M. Tomita, 2017, Journal of hepatology.

Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication.

M. Kurimoto, S. Kakinuma, N. Sakamoto, 2006, Hepatology research : the official journal of the Japan Society of Hepatology.

Bone morphogenetic protein‐4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells

S. Kakinuma, M. Nakagawa, Y. Asahina, 2017, Hepatology research : the official journal of the Japan Society of Hepatology.

Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells.

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2016, Biochemical and biophysical research communications.

Inhibitory Effect of a Triterpenoid Compound, with or without Alpha Interferon, on Hepatitis C Virus Infection

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2011, Antimicrobial Agents and Chemotherapy.

Impact of eradication of hepatitis C virus on liver-related and -unrelated diseases: morbidity and mortality of chronic hepatitis C after SVR

S. Kakinuma, M. Nakagawa, Y. Asahina, 2022, Journal of Gastroenterology.

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

A. Koike, M. Honda, M. Kurosaki, 2009, Nature Genetics.

Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2016, Scientific reports.

Specific inhibition of hepatitis C virus replication by cyclosporin A.

N. Enomoto, M. Kurosaki, S. Kakinuma, 2004, Biochemical and biophysical research communications.

Expressional screening of interferon‐stimulated genes for antiviral activity against hepatitis C virus replication

N. Enomoto, M. Kurosaki, S. Kakinuma, 2006, Journal of viral hepatitis.

LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2019, Scientific Reports.

Primary hepatic neuroendocrine carcinoma with a cholangiocellular carcinoma component in one nodule

S. Kakinuma, M. Nakagawa, T. Akashi, 2014, Clinical Journal of Gastroenterology.

Diabetes Mellitus May Be Associated with Hepatocarcinogenesis in Patients with Chronic Hepatitis C

M. Nakagawa, J. Tazawa, Y. Sakai, 2002, Digestive Diseases and Sciences.

Analysis of Interferon Signaling by Infectious Hepatitis C Virus Clones with Substitutions of Core Amino Acids 70 and 91

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2011, Journal of Virology.

IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.

M. Imamura, N. Hiraga, K. Chayama, 2010, Virology.

Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors.

N. Enomoto, M. Honda, S. Kaneko, 2011, Journal of hepatology.

Serum granulysin levels as a predictor of serious telaprevir‐induced dermatological reactions

M. Nakagawa, Y. Asahina, R. Abe, 2015, Hepatology research : the official journal of the Japan Society of Hepatology.

Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA

M. Yano, N. Enomoto, N. Sakamoto, 2007, Journal of gastroenterology and hepatology.

Regulation of Hepatitis C Virus Replication by Interferon Regulatory Factor 1

N. Enomoto, M. Kurosaki, S. Kakinuma, 2004, Journal of Virology.

Hepatocellular carcinoma recurrence after direct-acting antiviral therapy: an individual patient data meta-analysis

J. Bruix, J. Dufour, X. Forns, 2021, Gut.

Antiviral effects of the interferon‐induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2009, Hepatology.

Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants.

M. Imamura, N. Hiraga, K. Chayama, 2010, Virology.

Association between alanine aminotransferase elevation and UGT1A1*6 polymorphisms in daclatasvir and asunaprevir combination therapy for chronic hepatitis C

N. Enomoto, M. Sakamoto, M. Nakagawa, 2018, Journal of Gastroenterology.

Site‐specific mutation of the interferon sensitivity‐determining region (ISDR) modulates hepatitis C virus replication

N Enomoto, N. Enomoto, M. Kurosaki, 2006, Journal of viral hepatitis.

Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.

H. Yoshiji, K. Ikeo, N. Enomoto, 2017, Gastroenterology.

Acute Gastric Mucosal Lesions Associated with Cytomegalovirus Infection in an Immunocompetent Adult

S. Kakinuma, M. Nakagawa, C. Sato, 2001, Journal of gastroenterology and hepatology.

Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C

N. Enomoto, M. Kurosaki, S. Kakinuma, 2014, Journal of Gastroenterology.

Evaluation of Interferon Resistance in Newly Established Genotype 1b Hepatitis C Virus Cell Culture System

S. Kakinuma, M. Nakagawa, S. Yagi, 2016, Journal of clinical and translational hepatology.

Hepatitis C virus non-structural proteins responsible for suppression of the RIG-I/Cardif-induced interferon response.

N. Enomoto, N. Sakamoto, M. Nakagawa, 2007, The Journal of general virology.

Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3

N. Enomoto, M. Kurosaki, N. Sakamoto, 2006, Journal of Gastroenterology.

Genome-Wide Association Study Identi fi es TLL 1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection

H. Yoshiji, K. Ikeo, N. Enomoto, 2017 .

Identification of Novel N-(Morpholine-4-Carbonyloxy) Amidine Compounds as Potent Inhibitors against Hepatitis C Virus Replication

M. Hagiwara, S. Kakinuma, N. Sakamoto, 2011, Antimicrobial Agents and Chemotherapy.

Hepatic IFNL4 expression is associated with non‐response to interferon‐based therapy through the regulation of basal interferon‐stimulated gene expression in chronic hepatitis C patients

S. Kakinuma, M. Nakagawa, N. Izumi, 2017, Journal of medical virology.

Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.

H. Nakauchi, S. Kakinuma, N. Sakamoto, 2011, Biochemical and biophysical research communications.

Studies on virus kinetics using infectious fluorescence‐tagged hepatitis C virus cell culture

S. Kakinuma, N. Sakamoto, M. Nakagawa, 2011, Hepatology research : the official journal of the Japan Society of Hepatology.

Serial measurement of Wisteria floribunda agglutinin positive Mac-2-binding protein is useful for predicting liver fibrosis and the development of hepatocellular carcinoma in chronic hepatitis C patients treated with IFN-based and IFN-free therapy

S. Kakinuma, M. Nakagawa, Y. Asahina, 2016, Hepatology International.

Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2016, Scientific Reports.

Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee-infectious HC-J4 isolate to replicate efficiently in Huh-7 cells.

N. Enomoto, M. Kurosaki, N. Sakamoto, 2004, Journal of viral hepatitis.

Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors

S. Kakinuma, M. Nakagawa, Y. Asahina, 2023, Hepatology research : the official journal of the Japan Society of Hepatology.

Sequences in the interferon sensitivity‐determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG‐interferon plus ribavirin: Data mining analysis

M. Kurosaki, N. Hiramatsu, M. Sakamoto, 2011, Journal of medical virology.

Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C

H. Nomura, H. Yoshiji, N. Enomoto, 2015, Human Genetics.

Diabetic Retinopathy as a Risk Factor Associated with the Development of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease

S. Kakinuma, M. Nakagawa, M. Tomita, 2019, Digestive Diseases.

Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs

S. Kakinuma, M. Nakagawa, Y. Asahina, 2020, Journal of Gastroenterology.

Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells

N. Enomoto, S. Kakinuma, N. Sakamoto, 2010, Journal of Gastroenterology.

661 COMPARISON OF HCV-ASSOCIATED GENE EXPRESSION AND CELL SIGNALING PATHWAYS IN CELLS WITH OR WITHOUT HCV REPLICON AND IN REPLICON-CURED CELLS

N. Enomoto, S. Kakinuma, N. Sakamoto, 2010 .

Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee‐infectious HC‐J4 isolate to replicate efficiently in Huh‐7 cells

N. Enomoto, M. Kurosaki, N. Sakamoto, 2004 .

Time course alterations of virus sequences and immunoglobulin titers in a chronic hepatitis E patient

S. Kakinuma, M. Nakagawa, Y. Asahina, 2019, Hepatology research : the official journal of the Japan Society of Hepatology.

A case of primary sclerosing cholangitis with unique clinical features for a 5-year follow up

S. Kakinuma, M. Nakagawa, Y. Asahina, 2016 .

Efficacy of additional radiofrequency ablation after transcatheter arterial chemoembolization for intermediate hepatocellular carcinoma

S. Kakinuma, M. Nakagawa, Y. Asahina, 2016, Hepatology research : the official journal of the Japan Society of Hepatology.

Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients

S. Kakinuma, M. Nakagawa, Y. Asahina, 2019, Scientific Reports.

Overexpression of interferon γ-inducible protein 10 in the liver of patients with type i autoimmune hepatitis identified by suppression subtractive hybridization

N. Enomoto, M. Kurosaki, N. Sakamoto, 2001, American Journal of Gastroenterology.

Comprehensive genetic analysis of cholangiolocellular carcinoma with a coexistent hepatocellular carcinoma‐like area and metachronous hepatocellular carcinoma

N. Enomoto, S. Kakinuma, M. Nakagawa, 2019, Hepatology research : the official journal of the Japan Society of Hepatology.

LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2019, Scientific Reports.

Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium.

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2019, Journal of hepatology.

Hepatitis C virus non-structural proteins responsible for suppression of the RIG-I/Cardif-induced interferon response.

N. Enomoto, N. Sakamoto, M. Nakagawa, 2007, The Journal of general virology.

Hepatitis C Virus Non-structural Proteins Responsible for Suppression of the Rig-i/cardif-induced Interferon Response

M. Nakagawa, Yuki Nishimura‐Sakurai, Cheng-Hsin Chen, 2007 .

Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus

H. Nakauchi, S. Kakinuma, M. Nakagawa, 2016, Scientific Reports.