D. Spiller

发表

Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

James R. Johnson, D. Broomhead, D. Kell, 2004, Science.

PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells

D. Spiller, M. White, L. Davies, 2011, Cell Death and Disease.

Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells

David A. Rand, David G. Spiller, David E. Nelson, 2010, Journal of Cell Science.

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

M. Rattray, T. Galla, D. Spiller, 2016, eLife.

Dynamic Analysis of Stochastic Transcription Cycles

Julian R. E. Davis, Claire V. Harper, D. Rand, 2011, PLoS biology.

Explorer Dynamic Analysis of Stochastic Transcription Cycles

Julian R. E. Davis, Claire V. Harper, D. Rand, 2011 .

Measurement of single-cell dynamics

David A. Rand, David G. Spiller, Christopher D. Wood, 2010, Nature.

Automated tracking of gene expression in individual cells and cell compartments

Norman W. Paton, Douglas B. Kell, Tony Griffiths, 2006, Journal of The Royal Society Interface.

Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells.

D. Spiller, R. Clark, R. V. Giles, 1998, Nucleic acids research.

Edible Mushroom (Agaricus bisporus) Lectin, Which Reversibly Inhibits Epithelial Cell Proliferation, Blocks Nuclear Localization Sequence-dependent Nuclear Protein Import*

D. Spiller, M. White, J. Smith, 1999, The Journal of Biological Chemistry.

Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein.

D. Spiller, A. McLennan, S. Abdelraheim, 2003, The Biochemical journal.

Mouse Nudt13 is a Mitochondrial Nudix Hydrolase with NAD(P)H Pyrophosphohydrolase Activity

D. Spiller, A. McLennan, S. Abdelraheim, 2017, The Protein Journal.

Population robustness arising from cellular heterogeneity

Claire V. Harper, D. Rand, D. Spiller, 2010, Proceedings of the National Academy of Sciences.

The Mitochondrial Network of Human Neutrophils: Role in Chemotaxis, Phagocytosis, Respiratory Burst Activation, and Commitment to Apoptosis 1

R. Moots, D. Spiller, S. Edwards, 2003, The Journal of Immunology.

Cathepsin L digestion of nanobioconjugates upon endocytosis.

Brahim Lounis, Daniel J Rigden, Mathias Brust, 2009, ACS nano.

Improving the intracellular delivery and molecular efficacy of antisense oligonucleotides in chronic myeloid leukemia cells: a comparison of streptolysin-O permeabilization, electroporation, and lipophilic conjugation.

D. Spiller, R. Clark, R. V. Giles, 1998 .

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states

Claire V. Harper, Pawel Paszek, William Rowe, 2016, Nature Communications.

Spatio-temporal protein dynamics in single living cells.

Claire V. Harper, D. Spiller, M. White, 2008, Current opinion in biotechnology.

Single-cell time-lapse imaging of the dynamic control of NF-κB signalling

David G. Spiller, Caroline A. Horton, C. Horton, 2007 .

Oscillations in NF-kappaB signaling control the dynamics of gene expression.

D B Kell, N Benson, D. Broomhead, 2004, Science.

Magnetic microspheres encoded with photoluminescent quantum dots for multiplexed detection

David G. Spiller, D. Spiller, I. Prior, 2007 .

Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O.

D. Spiller, D. Tidd, David G. Spiller, 1995, Antisense research and development.

Enhanced Antisense Effects Resulting from an Improved Streptolysin-O Protocol for Oligodeoxynucleotide Delivery into Human Leukaemia Cells

D. Spiller, R. V. Giles, J. Grzybowski, 1997 .

D. Spiller, R. Clark, R. V. Giles, 1998, Blood.

Asymmetry between Activation and Deactivation during a Transcriptional Pulse

Anne V. McNamara, Julian R. E. Davis, Claire V. Harper, 2017, Cell systems.

Spatially coordinated dynamic gene transcription in living pituitary tissue

Hiroshi Momiji, Karen Featherstone, Anne V. McNamara, 2015, eLife.

Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling

J. Śmieja, M. Kimmel, D. Spiller, 2020, Cell Communication and Signaling.

Heat shock response pathways regulate stimulus-specificity and sensitivity of NF-κB signalling to temperature stress

J. Śmieja, M. Kimmel, D. Spiller, 2019, bioRxiv.

Dynamic interactions and intracellular fate of label-free GO within mammalian cells: role of lateral sheet size

D. Spiller, Kostas Kostarelos, S. Vranic, 2019, bioRxiv.

Tuneable mechanical properties in low molecular weight gels

D. Spiller, S. King, A. Paul, 2011 .

Is frequency-encoding of information a major theme in cellular processes?

D. Spiller, M. White, 2009, Cell cycle.

Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation

J. Śmieja, D. Spiller, P. Paszek, 2022, bioRxiv.

Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol

D. Spiller, M. White, J. Boyd, 2017, Scientific Reports.

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

V. Poroikov, V. M. D. Martins dos Santos, A. Kel, 2020, Disease Models & Mechanisms.

Identification of a novel therapeutic agent for Inflammatory Bowel Disease guided by systems medicine

V. Poroikov, A. Kel, D. Spiller, 2019 .

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

V. M. D. Martins dos Santos, D. Spiller, M. White, 2019, Frontiers in immunology.

In situ detection and measurement of intracellular reactive oxygen species in single isolated mature skeletal muscle fibers by real time fluorescence microscopy.

D. Spiller, M. Jackson, J. Palomero, 2008, Antioxidants & redox signaling.

Single-cell imaging reveals non-cooperative and cooperative infection strategies of Listeria monocytogenes in macrophages

D. Spiller, P. Paszek, J. Bagnall, 2022, bioRxiv.

Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia

V. Sée, D. Spiller, M. White, 2014, The Journal of Biological Chemistry.

1 Tight control of Hypoxia Inducible Factor (HIF)-alpha transient dynamics is essential for cell survival in

V. Sée, D. Spiller, M. White, 2013 .

The molecular action of the novel insecticide, Pyridalyl.

D. Spiller, M. White, M. Prescott, 2011, Insect biochemistry and molecular biology.

Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides.

D. Spiller, R. V. Giles, D. Tidd, 1995, Antisense research and development.

Optimization of antisense oligodeoxynucleotide structure for targeting bcr-abl mRNA.

D. Spiller, R. Clark, R. V. Giles, 1995, Blood.

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

D. Brough, D. Spiller, M. White, 2016, Methods in molecular biology.

Dynamic analysis of STAT6 signalling in living cells

G. Nelson, D. Spiller, J. Unitt, 2002, FEBS letters.

ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER–plasma membrane junctions

D. Spiller, M. White, L. Paraoan, 2019, Cell Death Discovery.

ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions

D. Spiller, M. White, L. Paraoan, 2019, bioRxiv.

Calcium dynamics and chromatin remodelling underlie heterogeneity in prolactin transcription

Anne V. McNamara, Julian R. E. Davis, Claire V. Harper, 2020, Journal of molecular endocrinology.

Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

A. Loudon, M. Hastings, D. Spiller, 2020, PLoS genetics.

Trafficking of osteonectin by retinal pigment epithelial cells: evidence for basolateral secretion.

G. Nelson, D. Spiller, M. White, 2007, The international journal of biochemistry & cell biology.

Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway

M. Rattray, D. Ray, C. Jørgensen, 2020, Journal of Cell Science.

Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism

M. Rattray, D. Bechtold, A. Loudon, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis.

D. Spiller, M. White, D. Fernig, 2005, American journal of respiratory cell and molecular biology.

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.

D. Spiller, S. Edwards, M. White, 2000, Blood.

Commitment to Apoptosis Phagocytosis , Respiratory Burst Activation , Neutrophils : Role in Chemotaxis , The Mitochondrial Network of Human Edwards

R. Moots, D. Spiller, M. White, 2003 .

Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells.

D. Spiller, R. V. Giles, D. Tidd, 1995, Nucleic acids research.

A simple method for preparing spectrally encoded magnetic beads for multiplexed detection.

D. Spiller, I. Prior, Robert Wilson, 2007, ACS nano.

Using systems medicine to identify a therapeutic agent with potential for repurposing in Inflammatory Bowel Disease

V. Poroikov, A. Kel, D. Spiller, 2019, bioRxiv.

The organisation of elastin and fibrillins 1 and 2 in the cruciate ligament complex

D. Spiller, P. Clegg, J. Innes, 2011, Journal of anatomy.

Orexin a preferentially excites glucose-sensitive neurons in the lateral hypothalamus of the rat in vitro.

D. Spiller, R. Morris, R. Morris, 2001, Diabetes.

Low molecular weight gelator-dextran composites.

Kyle L. Morris, L. Serpell, D. Spiller, 2010, Chemical communications.

CLL, but not normal, B cells are dependent on autocrine VEGF and alpha4beta1 integrin for chemokine-induced motility on and through endothelium.

D. Spiller, J. Cawley, Robert J. Harris, 2005, Blood.

CLL, but not normal, B cells are dependent on autocrine VEGF and (cid:1) 4 (cid:2) 1 integrin for chemokine-induced motility on and through endothelium

D. Spiller, Robert J. Harris, K. Till, 2005 .

Serine 162, an Essential Residue for the Mitochondrial Localization, Stability and Anti-Apoptotic Function of Mcl-1

R. Moots, D. Spiller, S. Edwards, 2012, PloS one.

TNF-α activates the human prolactin gene promoter via NF-κB signaling

Davis, Claire V. Harper, G. Nelson, 2007 .

Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappa B signaling

G. Nelson, D. Spiller, M. White, 2007 .

Chimeric oligodeoxynucleotide analogs: chemical synthesis, purification, and molecular and cellular biology protocols.

D. Spiller, R. V. Giles, D. Tidd, 2000, Methods in enzymology.

Integration between different hypothalamic nuclei involved in stress and GnRH secretion in the ewe.

H. Dobson, D. Spiller, R. Morris, 2010, Reproduction in domestic animals = Zuchthygiene.

Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis?

R. Moots, D. Spiller, S. Edwards, 2010, Annals of the rheumatic diseases.

Abrogation of c-MYC protein degradation in human lymphocyte lysates by prior precipitation with perchloric acid.

D. Spiller, D. Tidd, 1992, Journal of immunological methods.

Precursor cystatin C in cultured retinal pigment epithelium cells: evidence for processing through the secretory pathway.

D. Spiller, M. White, I. Grierson, 2001, Molecular membrane biology.

Heterodimeric interaction and interfaces of S100A1 and S100P.

D. Spiller, P. Rudland, Z. Rao, 2004, The Biochemical journal.

The influence of target protein half-life on the effectiveness of antisense oligonucleotide analog-mediated biologic responses.

D. Spiller, R. Clark, R. V. Giles, 1998, Antisense & nucleic acid drug development.

A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility.

G. Nelson, D. Spiller, M. White, 2007, Experimental eye research.

Identification of a good c-myc antisense oligodeoxynucleotide target site and the inactivity at this site of novel NCH triplet--targeting ribozymes.

D. Spiller, R. Clark, R. V. Giles, 1999, Nucleosides & nucleotides.

Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH.

K. Kirk, K. Saliba, D. Spiller, 2002, Molecular and biochemical parasitology (Print).

Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging

V. Sée, D. Spiller, I. Prior, 2010 .

Transcription Factor Pit-1 Affects Transcriptional Timing in the Dual-Promoter Human Prolactin Gene

Anne V. McNamara, Julian R. E. Davis, Claire V. Harper, 2021, Endocrinology.

Disentangling juxtacrine from paracrine signalling in dynamic tissue

David A. Rand, Hiroshi Momiji, Kirsty L. Hassall, 2019, PLoS Comput. Biol..

Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans.

David Grundy, Andrea Varro, Wen Jiang, 2003, Gastroenterology.

Expression of the leptin receptor in rat and human nodose ganglion neurones

D. Thompson, D. Spiller, R. Morris, 2002, Neuroscience.

Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo

D. Scherman, D. Spiller, M. White, 2001, Nature Biotechnology.

The effect of polymer additives on the rheological properties of dipeptide hydrogelators

D. Spiller, D. Adams, Lin Chen, 2012 .

Calcium-dependent regulation of the cell cycle via a novel MAPK–NF-κB pathway in Swiss 3T3 cells

V. Sée, D. Spiller, M. White, 2004, The Journal of cell biology.

Microencapsulation using an oil-in-water-in-air 'dry water emulsion'.

A. Cooper, D. Spiller, D. Adams, 2011, Chemical communications.

The Digestive Food Vacuole of the Malaria Parasite Is a Dynamic Intracellular Ca2+ Store*

D. Spiller, M. White, G. Biagini, 2003, Journal of Biological Chemistry.

The complement regulatory proteins CD55 (decay accelerating factor) and CD59 are expressed on the inner acrosomal membrane of human spermatozoa as well as CD46 (membrane cofactor protein)

D. Spiller, P. Johnson, B. Flanagan, 2006, Immunology.

Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity.

D. Spiller, R. V. Giles, D. Tidd, 1993, Anti-cancer drug design.

The uptake kinetics of chimeric oligodeoxynucleotide analogues in human leukaemia MOLT-4 cells.

D. Spiller, D. Tidd, 1992, Anti-cancer drug design.

Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA.

D. Spiller, R. Clark, R. V. Giles, 1999, Antisense & nucleic acid drug development.

Determination of optimal sites of antisense oligonucleotide cleavage within TNFalpha mRNA.

D. Spiller, R. V. Giles, J. Grzybowski, 2001, Nucleic acids research.

Oligodeoxynucleotide 5mers containing a 5'-CpG induce apoptosis through a mitochondrial mechanism in T lymphocytic leukaemia cells.

D. Spiller, R. Clark, R. V. Giles, 2000, Nucleic acids research.

Mechanical properties of the ovine cervix during pregnancy, labour and immediately after parturition.

H. Dobson, D. Spiller, R. Fitzpatrick, 1991, The British veterinary journal.

Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing

Anne V. McNamara, Julian R. E. Davis, D. Spiller, 2015, Molecular endocrinology.

P53 apoptosis mediator PERP: localization, function and caspase activation in uveal melanoma

D. Spiller, L. Davies, I. Grierson, 2009, Journal of cellular and molecular medicine.

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

D. Spiller, M. White, R. Brignall, 2018, Science Signaling.

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

Claire V. Harper, Pawel Paszek, Lloyd Bridge, 2016, eLife.

The Saccharomyces cerevisiae PCD1 Gene Encodes a Peroxisomal Nudix Hydrolase Active toward Coenzyme A and Its Derivatives*

D. Spiller, A. McLennan, J. Cartwright, 2000, The Journal of Biological Chemistry.

Complexities in the role of acetylation dynamics in modifying inducible gene activation parameters

Yaoyong Li, A. Sharrocks, D. Spiller, 2021, bioRxiv.

Density-dependent location and interactions of truncated APC and β-catenin

D. Spiller, J. A. Wakeman, G. Roberts, 2004, Oncogene.

Lymphocyte subpopulations in peripheral blood of lambs experimentally infected with bovine respiratory syncytial virus.

D. Spiller, H. Warenius, Z. Woldehiwet, 1990, Veterinary immunology and immunopathology.

Pulsatile Stimulation Determines Timing and Specificity of NF-κB-Dependent Transcription

D. S. Broomhead, Claire V. Harper, D. Broomhead, 2009, Science.

p63 is required beside p53 for PERP-mediated apoptosis in uveal melanoma

D. Spiller, M. White, L. Paraoan, 2016, British Journal of Cancer.

Multi-parameter analysis of the kinetics of NF-kappaB signalling and transcription in single living cells.

David G Spiller, G. Nelson, D. Spiller, 2002, Journal of cell science.

Quantitative measurement of single cell dynamics.

David G Spiller, D. Spiller, M. White, 2012, Current opinion in biotechnology.

Encoded microcarriers for high-throughput multiplexed detection.

David G Spiller, Andrew R Cossins, Robert Wilson, 2006, Angewandte Chemie.

Ploidy as a prognostic indicator in end stage squamous cell carcinoma of the head and neck region treated with cisplatinum.

F. Bootz, T. Helliwell, D. Spiller, 1990, British Journal of Cancer.

HP1α guides neuronal fate by timing E2F‐targeted genes silencing during terminal differentiation

V. Sée, D. Spiller, G. Almouzni, 2007, The EMBO journal.

Response to Comment on "Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression"

Douglas B. Kell, David G. Spiller, David E. Nelson, 2005, Science.

Variations in cell morphology in the canine cruciate ligament complex.

D. Spiller, P. Clegg, J. Innes, 2012, Veterinary journal.

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy

Stephen S. Taylor, D. Ray, D. Spiller, 2015, Proceedings of the National Academy of Sciences.

Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth.

D. Spiller, M. White, D. Fernig, 2006, American journal of physiology. Lung cellular and molecular physiology.

Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis

M. Rattray, T. Galla, D. Spiller, 2018, Nature Communications.

Quantitative, real-time, single cell analysis in tissue reveals expression dynamics of neurogenesis

M. Rattray, T. Galla, D. Spiller, 2018, bioRxiv.

Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

A. Loudon, E. Maywood, M. Hastings, 2016, Current Biology.

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

D. Spiller, M. White, R. Brignall, 2015, Integrative biology : quantitative biosciences from nano to macro.

Density-dependent location and interactions of truncated APC and beta-catenin.

D. Spiller, J. A. Wakeman, G. Roberts, 2004, Oncogene.

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

V. Sée, D. Spiller, M. White, 2010, Cell Death and Disease.

Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway.

M. Rattray, D. Ray, C. Jørgensen, 2020, Journal of cell science.

Tumor Necrosis Factor-α Activates the Human Prolactin Gene Promoter via Nuclear Factor-κB Signaling

Julian R. E. Davis, G. Nelson, D. Spiller, 2006 .

Dynamic patterns of growth hormone gene transcription in individual living pituitary cells.

Julian R. E. Davis, A. Loudon, D. Spiller, 2003, Molecular endocrinology.

Quantitative Characterisation of Low Abundant Yeast Mitochondrial Proteins Reveals Compensation for Haplo-Insufficiency in Different Environments

D. Delneri, D. Spiller, M. White, 2021, bioRxiv.

Live Imaging of Label-Free Graphene Oxide Reveals Critical Factors Causing Oxidative-Stress-Mediated Cellular Responses.

Kostas Kostarelos, Sandra Vranic, Cyrill Bussy, 2017, ACS nano.

Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression

D. Spiller, P. Paszek, D. Jackson, 2023, bioRxiv.

Temperature regulates NF-κB dynamics and function through timing of A20 transcription

P Downton, D A Rand, D. Rand, 2018, Proceedings of the National Academy of Sciences.

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

Christine Kinnon, David G. Spiller, Adrian J. Thrasher, 2007, The Journal of experimental medicine.

Cell motility in chronic lymphocytic leukemia: defective Rap1 and alphaLbeta2 activation by chemokine.

D. Spiller, J. Cawley, A. Linford, 2008, Cancer research.

Cell Motility in Chronic Lymphocytic Leukemia: Defective Rap1 and A L B 2 Activation by Chemokine

D. Spiller, A. Linford, Robert J. Harris, 2008 .

Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model.

Julian R. E. Davis, D. Spiller, M. White, 2009, Molecular endocrinology.

Dynamic interactions and intracellular fate of label-free, thin graphene oxide sheets within mammalian cells: role of lateral sheet size

D. Spiller, Kostas Kostarelos, S. Vranic, 2021, Nanoscale advances.

Prediction of recurrence in pituitary tumours: a flow cytometric study using in vivo bromodeoxyuridine.

D. Spiller, G. Forster, P. May, 1993, British journal of neurosurgery.

Distinct roles for Caf1, Ccr4, Edc3 and CutA in the co‐ordination of transcript deadenylation, decapping and P‐body formation in Aspergillus nidulans

D. Spiller, D. Rigden, Christoph Dattenböck, 2010, Molecular microbiology.

Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

A. Loudon, K. Strimmer, M. Hastings, 2022, eLife.

NF-κB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms

D. Ray, G. Nelson, D. Spiller, 2003, Journal of Cell Science.

Heterodimerisation and the heterodimeric interfaces of S100A1 and S100P

Shu Zhang, Hongmei Zhang, Yi Ding, 2004 .

The pH of the Plasmodium falciparum digestive vacuole: holy grail or dead-end trail?

Ruth H. Hughes, D. Spiller, M. White, 2002, Trends in parasitology.

Quanti � cation of protein abundance 1 and interaction de � nes a mechanism 2 for operation of the circadian clock

K. Strimmer, M. Hastings, D. Spiller, 2022 .

Cell Cycle Phase Regulates Glucocorticoid Receptor Function

D. Spiller, M. White, James Johnson, 2011, PloS one.

Unexpected Intracellular Localization of the AMD‐Associated Cystatin C Variant

D. Spiller, M. White, I. Grierson, 2004, Traffic.

Changes in the extensibility of the ovine cervix uteri following infusion of estradiol-17 β at term

D. Spiller, R. Fitzpatrick, J. Owiny, 1992 .

Scanning electron microscopy of the wall of the ovine cervix uteri in relation to tensile strength at parturition.

D. Spiller, J. Appleton, R. Fitzpatrick, 1987, Research in veterinary science.

Dynamic NF-kB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

V. Sée, D. Spiller, M. White, 2016 .

Fluorescent or not? Size-dependent fluorescence switching for polymer-stabilized gold clusters in the 1.1-1.7 nm size range.

Molly M Stevens, Raphaël Lévy, David G Spiller, 2008, Chemical communications.

Information management for high content live cell imaging

Norman W. Paton, Neil Swainston, Douglas B. Kell, 2009, BMC Bioinformatics.

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level

Jaroslaw Smieja, Marek Kimmel, Malgorzata Kardynska, 2018, PLoS Comput. Biol..

Interactive segmentation of clustered cells via geodesic commute distance and constrained density weighted Nyström method

Marco Marcello, Till Bretschneider, Cheng-Jin Du, 2010, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis

M. Rattray, T. Galla, D. Spiller, 2019, Nature Communications.

Live-cell imaging reveals single-cell and population-level infection strategies of Listeria monocytogenes in macrophages

D. Spiller, P. Paszek, J. Bagnall, 2023, Frontiers in immunology.

Alteration of cellular immune responses by nutrition and weaning in calves.

D. Spiller, T. Rowan, D. Spiller, 1993, Research in veterinary science.

Dynamic organisation of prolactin gene expression in living pituitary tissue

Karen Featherstone, David G. Spiller, Julian R. E. Davis, 2010, Journal of Cell Science.

Quantification of circadian interactions and protein abundance defines a mechanism for operational stability of the circadian clock

A. Loudon, K. Strimmer, T. House, 2021, bioRxiv.

Quantitative single-cell live imaging links HES 5 dynamics with cell-state 5 and fate in murine neurogenesis 6

T. Galla, D. Spiller, N. Papalopulu, 2019 .

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy

Stephen S. Taylor, D. Ray, D. Spiller, 2015, Proceedings of the National Academy of Sciences.

Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling.

Julian R. E. Davis, Claire V. Harper, G. Nelson, 2006, Endocrinology.

Cell motility in chronic lymphocytic leukemia: defective Rap1 and alphaLbeta2 activation by chemokine.

D. Spiller, J. Cawley, A. Linford, 2008, Cancer research.

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

D. Brough, D. Spiller, M. White, 2016, Cell Death and Differentiation.

Further comments on the distribution of acridine orange fluorescence in P-falciparum-infected erythrocytes

K. Kirk, K. Saliba, D. Spiller, 2002 .

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

D. Spiller, M. White, P. Paszek, 2015, Integrative biology : quantitative biosciences from nano to macro.

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

D. Spiller, M. White, A. Thrasher, 2007, The Journal of experimental medicine.