Zhihong Guo

M. Mattson, Zhihong Guo, M. Kindy, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor.

M. Mattson, Zhihong Guo, W. Duan, 2003, Endocrinology.

Progress in the Development of Caloric Restriction Mimetic Dietary Supplements

M. Mattson, D. Ingram, Zhihong Guo, 2001 .

Leptin-mediated Cell Survival Signaling in Hippocampal Neurons Mediated by JAK STAT3 and Mitochondrial Stabilization*

M. Mattson, Xiangru Xu, Zhihong Guo, 2008, Journal of Biological Chemistry.

Pancortin-2 Interacts with WAVE1 and Bcl-xL in a Mitochondria-Associated Protein Complex That Mediates Ischemic Neuronal Death

M. Mattson, Zhihong Guo, T. Arumugam, 2007, The Journal of Neuroscience.

Solid‐Phase Total Synthesis and Antimicrobial Activities of Loloatins A–D

Zhihong Guo, W. Niu, Chuanguang Qin, 2007, Chemistry & biodiversity.

Biomimetic synthesis of gramicidin s and analogues by enzymatic cyclization of linear precursors on solid support.

Zhihong Guo, Ka Man Wong, Xiaoming Wu, 2003, Organic letters.

p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults

M. Mattson, N. Greig, XiaoXiang Zhu, 2007, NeuroMolecular Medicine.

Listeria monocytogenes MenI Encodes a DHNA-CoA Thioesterase Necessary for Menaquinone Biosynthesis, Cytosolic Survival, and Virulence

Zhihong Guo, J. Sauer, Grischa Y Chen, 2020, Infection and Immunity.

Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development.

Charles D. Smith, M. Mattson, W. Markesbery, 2003, Neuromolecular medicine.

Expression, Purification, and Characterization of TylM1, an N,N-Dimethyltransferase Involved in the Biosynthesis of Mycaminose

Zhihong Guo, Hung‐wen Liu, Huawei Chen, 1998 .

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake

Mark P. Mattson, Donald K. Ingram, R. de Cabo, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Using beta-lactamase to trigger supramolecular hydrogelation.

Bing Xu, Zhihong Guo, G. Liang, 2007, Journal of the American Chemical Society.

Using β-lactamase to trigger supramolecular hydrogelation

Bing Xu, Zhihong Guo, G. Liang, 2007 .

Biosynthesis of mycarose: Isolation and characterization of enzymes involved in the C-2 deoxygenation

Zhihong Guo, Hung‐wen Liu, Huawei Chen, 1999 .

Mechanistic studies of the biosynthesis of 3,6-dideoxy sugars: Stereochemical analysis of C-3 deoxygenation

Zhihong Guo, Hung‐wen Liu, P. A. Pieper, 1995 .

Synthesis and Characterization of Substituted μ-oxo-bis[tetra-phenylporphyrinatoiron] Compounds

Shu Ying Chen, Lu Hai Li, Zhi Peng Guo, 2015 .

Optimization of antibacterial cyclic decapeptides.

Zhihong Guo, Xiaofen Zhong, Xianzhang Bu, 2004, Journal of combinatorial chemistry.

Dissociation of antibacterial and hemolytic activities of an amphipathic peptide antibiotic.

Chuanguang Qin, Zhihong Guo, Zhihong Guo, 2003, Journal of medicinal chemistry.

An improved deblocking agent for direct Fmoc solid-phase synthesis of peptide thioesters

Zhihong Guo, Xianzhang Bu, Guiyang Xie, 2002 .

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles.

Bing Xu, Rongkun Zheng, Chenjie Xu, 2004, Journal of the American Chemical Society.

Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice

M. Mattson, Zhihong Guo, Y. Matsuoka, 2007, Experimental Neurology.

A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats

D. Ingram, B. Shukitt-Hale, J. Joseph, 2008, Neurobiology of Aging.

Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase.

Zhihong Guo, Hung‐wen Liu, Z. Zhao, 2001, Angewandte Chemie.

Synthesis and Phase-transition of 4-alkoxycarbonylphenyl 4′-n-alkoxy-2,3,5, 6-tetrafluorobiphenyl-4-carboxylates

Zhihong Guo, J. Wen, M. Tian, 1996 .

Novel fluorinated liquid crystals. Part 9.—Synthesis and mesomorphic properties of 4-(n-alkoxycarbonyl)phenyl 4-[(4-n-alkoxy-2,3,5,6-tetrafluorophenyl)ethynyl]benzoates

Zhihong Guo, J. Wen, M. Tian, 1994 .

A Comparative Study of Ferric Nitrate and Citric Acid in Washing Heavy Metal-Contaminated Soil

Zhihong Guo, L. Shuang, D. Ren, 2021, Environmental Engineering Science.

Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways.

Zhihong Guo, M. Jiang, Jiahai Zhou, 2012, Biochemistry.

Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

C. Culmsee, M. Mattson, Zhihong Guo, 2000, The Journal of Neuroscience.

The thiamine-dependent enzyme of the vitamin K biosynthesis catalyzes reductive C-N bond ligation between nitroarenes and α-ketoacids

Zhihong Guo, Minjiao Chen, M. Jiang, 2013, Science China Chemistry.

Intracellular hydrogelation of small molecules inhibits bacterial growth.

Bing Xu, Zu-feng Guo, Zhihong Guo, 2007, Angewandte Chemie.

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

M. Mattson, Zhihong Guo, Xiao-Jiang Li, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Effect of pollen typhae on inhibiting autophagy in spinal cord injury of rats and its mechanisms.

Zhihong Guo, Xuecheng Cao, Zhan-wang Xu, 2015, International journal of clinical and experimental pathology.

Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution.

Zhihong Guo, Xiaoming Wu, Xianzhang Bu, 2002, Organic letters.

Single‐Turnover Kinetics Reveal a Distinct Mode of Thiamine Diphosphate‐Dependent Catalysis in Vitamin K Biosynthesis

Zhihong Guo, W. Chan, Xin Dai, 2018, Chembiochem : a European journal of chemical biology.

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

Bo Zhou, Andrea Ballabio, Min Li, 2016, Autophagy.

Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior

Wenzhen Duan, Mark P Mattson, Aiwu Cheng, 2002, Neurobiology of Aging.

Identification of a Hotdog Fold Thioesterase Involved in the Biosynthesis of Menaquinone in Escherichia coli

Zhihong Guo, Minjiao Chen, M. Jiang, 2013, Journal of bacteriology.

Identification of a nonaketide product for the iterative polyketide synthase in biosynthesis of the nine-membered enediyne C-1027.

Zu-feng Guo, Zhihong Guo, K. Sze, 2010, Angewandte Chemie.

Catalytic mechanism of SHCHC synthase in the menaquinone biosynthesis of Escherichia coli: identification and mutational analysis of the active site residues.

Zhihong Guo, Xian-Hui Wu, Yundong Wu, 2009, Biochemistry.

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

Richard D. Leapman, Mark P. Mattson, M. Mattson, 2005, Science.

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

B. H. Miller, C. Wahlestedt, Zhihong Guo, 2018, Neurobiology of Disease.

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β‐peptide

C. Culmsee, M. Mattson, N. Greig, 2001 .

Seizures and Tissue Injury Induce Telomerase in Hippocampal Microglial Cells

M. Mattson, Zhihong Guo, Jaewon Lee, 2002, Experimental Neurology.

Substrate Recognition and Catalytic Mechanism of the Phosphate Acyltransferase PlsX from Bacillus subtilis

Zhihong Guo, Mingming Qin, Yiping Jiang, 2020, Chembiochem : a European journal of chemical biology.

Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis.

Zhihong Guo, Xin Dai, Mingming Qin, 2018, The Biochemical journal.

Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms

M. Mattson, Zhihong Guo, W. Duan, 2003, Journal of neurochemistry.

Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms

M. Mattson, Zhihong Guo, Jaewon Lee, 2001, Mechanisms of Ageing and Development.

Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors.

Zhihong Guo, Xiaoming Wu, Gannon C.K. Mak, 2004, The Journal of organic chemistry.

Combination of beta-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites.

Zhihong Guo, Z. Cai, Yufang Zheng, 2009, Talanta.

Chip‐based CE coupled to a quadrupole TOF mass spectrometer for the analysis of a glycopeptide

Zhihong Guo, Haifang Li, Jin‐Ming Lin, 2007, Electrophoresis.

Effects of Macromolecular Crowding on the Intrinsic Catalytic Efficiency and Structure of Enterobactin-Specific Isochorismate Synthase

Zhihong Guo, M. Jiang, 2007 .

Effects of macromolecular crowding on the intrinsic catalytic efficiency and structure of enterobactin-specific isochorismate synthase.

Zhihong Guo, M. Jiang, 2007, Journal of the American Chemical Society.

Soluble Neuroprotective Antioxidant Uric Acid Analogs Ameliorate Ischemic Brain Injury in Mice

M. Mattson, Sung-Chun Tang, N. Greig, 2007, NeuroMolecular Medicine.

Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins.

Bing Xu, Rongkun Zheng, Chenjie Xu, 2004, Journal of the American Chemical Society.

An Atypical α/β-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae.

Zhihong Guo, Xinyun Cao, J. Cronan, 2016, Biochemistry.

Fast Delivery of Multifunctional NIR‐II Theranostic Nanoaggregates Enabled by the Photoinduced Thermoacoustic Process

J. Lam, Zhihong Guo, Lian-rui Hu, 2023, Advanced science.

Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase*

Zhihong Guo, Yaozong Chen, Yueru Sun, 2015, The Journal of Biological Chemistry.

Rare earth magnets resisting eddy currents

Weiguang Li, Zhihong Guo, Weiguang Li, 1999 .

Paroxetine retards disease onset and progression in Huntingtin mutant mice

M. Mattson, Xiangru Xu, J. Cadet, 2004, Annals of neurology.

Biosynthesis of yersiniose: Attachment of the two-carbon branched-chain is catalyzed by a thiamine pyrophosphate-dependent flavoprotein

Zhihong Guo, Hung‐wen Liu, Huawei Chen, 1998 .

Cascade biocatalysis by multienzyme-nanoparticle assemblies.

Zhihong Guo, Jiang Xia, Jianpeng Wang, 2014, Bioconjugate chemistry.

Beneficial Effects of Dietary Restriction on Cerebral Cortical Synaptic Terminals

M. Mattson, D. Butterfield, Zhihong Guo, 2000, Journal of neurochemistry.

Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury

M. Mattson, Zhihong Guo, Jaewon Lee, 2007, Journal of Molecular Neuroscience.

Participation of Par-4 in the Degeneration of Striatal Neurons Induced by Metabolic Compromise with 3-Nitropropionic Acid

M. Mattson, Zhihong Guo, W. Duan, 2000, Experimental Neurology.

Neuroprotective effects of PPAR‐γ agonist rosiglitazone in N171‐82Q mouse model of Huntington's disease

C. Ross, J. Troncoso, Zhihong Guo, 2013, Journal of neurochemistry.

A Universal and Facile Approach for the Formation of a Protein Hydrogel for 3D Cell Encapsulation

I. Hsing, Hongkai Wu, Zhihong Guo, 2015 .

Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat‐shock proteins and Bcl‐2

M. Mattson, Zhihong Guo, Jaewon Lee, 2001, Journal of neurochemistry.

Structural Basis of the Induced-Fit Mechanism of 1,4-Dihydroxy-2-Naphthoyl Coenzyme A Synthase from the Crotonase Fold Superfamily

Zhihong Guo, M. Jiang, Jiahai Zhou, 2013, PloS one.

Prophylactic activation of neuroprotective stress response pathways by dietary and behavioral manipulations

M. Mattson, Zhihong Guo, W. Duan, 2011, NeuroRX.

Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues.

Zhihong Guo, M. Jiang, Haigang Song, 2014, Acta crystallographica. Section D, Biological crystallography.

Stabilization of the second oxyanion intermediate by 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase of the menaquinone pathway: spectroscopic evidence of the involvement of a conserved aspartic acid.

Zhihong Guo, Minjiao Chen, M. Jiang, 2011, Biochemistry.

Structure and Reactivity of Bacillus subtilis MenD Catalyzing the First Committed Step in Menaquinone Biosynthesis

W. Hunter, Zhihong Guo, P. Fyfe, 2010, Journal of molecular biology.

Facile formation of a microporous chitosan hydrogel based on self-crosslinking.

K. Boheler, Hongkai Wu, Zhihong Guo, 2017, Journal of materials chemistry. B.

Structural change of the enterobactin synthetase in crowded solution and its relation to crowding-enhanced product specificity in nonribosomal enterobactin biosynthesis.

Zhihong Guo, M. Jiang, Suilan Zheng, 2010, Bioorganic & medicinal chemistry letters.

Microsecond protein folding events revealed by time-resolved fluorescence resonance energy transfer in a microfluidic mixer.

Zhihong Guo, S. Yao, J. Qu, 2015, Analytical chemistry.

Identification and Characterization of a Methionine γ‐Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora

Zhihong Guo, Haigang Song, Ri Xu, 2015, Chembiochem : a European journal of chemical biology.

Impaired long‐term depression in P2X3 deficient mice is not associated with a spatial learning deficit

M. Mattson, D. Ingram, Zhihong Guo, 2006, Journal of neurochemistry.

Cellular and molecular mechanisms whereby dietary restriction extends healthspan: a beneficial type of stress

M. Mattson, Zhihong Guo, W. Duan, 2003 .

Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains

Zhihong Guo, Xin Dai, Mingming Qin, 2019, Communications Biology.

The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme.

Zhihong Guo, Hung‐wen Liu, Jenefer Alam, 2003, Journal of the American Chemical Society.

Phenylacetyl pepstatin inhibitors of aspartyl proteases from Streptomyces varsoviensis

Zhihong Guo, Weijian Ye, 2022, The Journal of Antibiotics.

Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains

Zhihong Guo, Xin Dai, Mingming Qin, 2019, Communications Biology.

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

M. Mattson, R. Leapman, R. Tycko, 2005, Science.

Enzyme-instructed molecular self-assembly confers nanofibers and a supramolecular hydrogel of taxol derivative.

Bing Xu, Zhihong Guo, Yuan Gao, 2009, Journal of the American Chemical Society.

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

A. Ballabio, Zhihong Guo, D. Medina, 2016, Autophagy.

Designing small-molecule switches for protein-protein interactions.

P G Schultz, P. Schultz, Zhihong Guo, 2000, Science.

EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia

B. H. Miller, C. Wahlestedt, Zhihong Guo, 2018, Neurobiology of Disease.

Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity.

Ming Jiang, Zhihong Guo, Minjiao Chen, 2007, Biochemistry.

Combination of beta-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites.

Zhihong Guo, Z. Cai, Yufang Zheng, 2009, Talanta.

8 Mark P. Mattson, Wenzhen Duan, Sic L. Chan, Apoptotic and Antiapoptotic Signaling at the Synapse: From Adaptive Plasticity to Neurodegenerative Disorders

Zhihong Guo, 2013 .

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake

R. de Cabo, M. Mattson, D. Ingram, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase.

Zhihong Guo, Hung‐wen Liu, Huawei Chen, 2001, Angewandte Chemie.