Azin Sayad

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Computational Modeling of Ovarian Cancer Reveals Optimal Strategies for Therapy and Screening

A. Oza, D. Levine, B. Neel, 2019 .

Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance

Gary D Bader, D. Pe’er, G. Mills, 2016, Cell.

A Biochemical Genomics Screen for Substrates of Ste20p Kinase Enables the In Silico Prediction of Novel Substrates

Anna Y. Lee, David Y. Thomas, M. Hallett, 2009, PloS one.

Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

Kevin R Brown, Troy Ketela, Frederick S. Vizeacoumar, 2012, Cancer discovery.

Supplemental Materials and Methods for : Essential gene profiles in breast , pancreas and ovarian cancer cells

Marianna, C., C. Misquitta, 2011 .

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

Sarah J. Kurley, Lukas M. Simon, Ido Golding, 2015, Nature.

Ontogeny and Vulnerabilities of Lapatinib Drug-Tolerant Persisters in HER2+ Breast Cancer

B. Ueberheide, J. Moffat, C. Sotiriou, 2020, bioRxiv.

Proteomic Dynamics of Breast Cancers Identifies Potential Therapeutic Protein Targets

R. Aebersold, W. Reinhold, Y. Pommier, 2022, bioRxiv.

IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function

Trevor J Pugh, B. Haibe-Kains, T. Pugh, 2020, Cancer Immunology Research.

Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening

Myles A Brown, A. Oza, D. Levine, 2021, Proceedings of the National Academy of Sciences.

Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.

B. Neel, Shengqing Gu, Azin Sayad, 2016, Blood.

Title Distinct GAB 2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL 1 Permalink

B. Neel, Shengqing Gu, Azin Sayad, 2016 .

Distinct GAB 2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL 1

B. Neel, Shengqing Gu, Azin Sayad, 2016 .

Coenzyme A fuels T cell anti-tumor immunity.

Trevor J Pugh, T. Pugh, J. Wargo, 2021, Cell metabolism.

SHP2 Is Required for BCR-ABL1-Induced Hematologic Neoplasia

B. Neel, Shengqing Gu, Azin Sayad, 2017, Leukemia.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Roland Arnold, Laurence Pelletier, Andrew Emili, 2013, Molecular systems biology.

COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines

Judice L. Y. Koh, Kevin R. Brown, Troy Ketela, 2011, Nucleic Acids Res..

Optimal Strategies for Therapy and Screening

A. Oza, D. Levine, B. Neel, 2021 .

High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation

B. Clarke, Azin Sayad, M. Bernardini, 2019, Journal of Immunotherapy for Cancer.

The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells

Tony Pawson, Igor Jurisica, Max Kotlyar, 2014, Nature Methods.

Integrated Genomic, Transcriptomic, and RNA-Interference Analysis of Genes in Somatic Copy Number Gains in Pancreatic Ductal Adenocarcinoma

T. Hudson, J. Moffat, L. Muthuswamy, 2013, Pancreas.

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer.

B. Ueberheide, J. Moffat, C. Sotiriou, 2021, Cancer discovery.

Overproduction of IFNγ by Cbl-b–Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity

Azin Sayad, P. Ohashi, A. Elford, 2022, Cancer immunology research.

A Genomically Characterized Collection of High-Grade Serous Ovarian Cancer Xenografts for Preclinical Testing.

B. Clarke, B. Neel, Azin Sayad, 2018, The American journal of pathology.

Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer

B. Clarke, H. Berman, Azin Sayad, 2019, Oncoimmunology.

Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire

Trevor J Pugh, T. Pugh, B. Clarke, 2023, Cancer Immunology, Immunotherapy.

Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer

J. Moffat, T. Pugh, T. Ketela, 2023, Communications biology.

Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets

R. Aebersold, W. Reinhold, Y. Pommier, 2023, Molecular & cellular proteomics : MCP.

SHP2 Is Required for BCR-ABL1-Induced Hematologic Neoplasms

B. Neel, Shengqing Gu, Azin Sayad, 2017, bioRxiv.

B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters

M. Kotlyar, Azin Sayad, D. Winer, 2023, bioRxiv.

Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance

Gary D Bader, D. Pe’er, G. Mills, 2016, Cell.

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer.

B. Ueberheide, J. Moffat, C. Sotiriou, 2021, Cancer discovery.

Integrated Genomic, Transcriptomic, and RNA-Interference Analysis of Genes in Somatic Copy Number Gains in Pancreatic Ductal Adenocarcinoma

T. Hudson, J. Moffat, L. Muthuswamy, 2013, Pancreas.

PD-1 regulates ILC3-driven intestinal immunity and homeostasis.

Azin Sayad, S. Nutt, D. Amann-Zalcenstein, 2024, Mucosal immunology.

Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy

Azin Sayad, A. Elford, K. Hezaveh, 2024, Cell reports. Medicine.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Philip M. Kim, Frederick S. Vizeacoumar, Glauber C. Brito, 2013, Molecular systems biology.

Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors

B. Clarke, Azin Sayad, L. Nguyen, 2024, Oncoimmunology.

Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer

Trevor J Pugh, J. Moffat, T. Ketela, 2023, Communications biology.