P. Welling

发表

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

Sanjiv J. Shah, J. O’Connell, A. Chakravarti, 2009, Proceedings of the National Academy of Sciences.

Primary structure and functional expression of a cGMP-gated potassium channel.

P. Welling, X. Yao, A. S. Segal, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Sorting it out in endosomes: an emerging concept in renal epithelial cell transport regulation.

P. Welling, O. Weisz, 2010, Physiology.

K depletion increases protein tyrosine kinase-mediated phosphorylation of ROMK.

G. Giebisch, P. Welling, H. Sterling, 2002, American journal of physiology. Renal physiology.

Cell Surface Expression of the ROMK (Kir 1.1) Channel Is Regulated by the Aldosterone-induced Kinase, SGK-1, and Protein Kinase A*

P. Welling, B. Y. Kim, D. Yoo, 2003, Journal of Biological Chemistry.

WNK1 kinase isoform switch regulates renal potassium excretion.

J. Wade, A. Subramanya, P. Welling, 2006, Proceedings of the National Academy of Sciences of the United States of America.

WNK4 Diverts the Thiazide-sensitive NaCl Cotransporter to the Lysosome and Stimulates AP-3 Interaction*

J. Wade, A. Subramanya, P. Welling, 2009, The Journal of Biological Chemistry.

Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium.

J. Wade, P. Welling, Tong Wang, 2011, American journal of physiology. Renal physiology.

Authors' Reply.

P. Welling, D. Batlle, M. Soler, 2020, Journal of the American Society of Nephrology : JASN.

A comprehensive guide to the ROMK potassium channel: form and function in health and disease.

P. Welling, K. Ho, 2009, American journal of physiology. Renal physiology.

An Andersen-Tawil Syndrome Mutation in Kir2.1 (V302M) Alters the G-loop Cytoplasmic K+ Conduction Pathway*

P. Welling, T. Rogers, Donghui Ma, 2007, Journal of Biological Chemistry.

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling

Turgay Saritas, Victor G. Puelles, P. Welling, 2018, Cell reports.

Rapid Development of Vasopressin Resistance in Dietary Potassium Deficiency.

P. Welling, P. Grimm, L. Al-Qusairi, 2021, American journal of physiology. Renal physiology.

Distal Convoluted Tubule Sexual Dimorphism Revealed by Advanced 3D-Imaging.

P. Welling, D. Ellison, R. Coleman, 2020, American journal of physiology. Renal physiology.

SPAK Isoforms and OSR1 Regulate Sodium-Chloride Co-transporters in a Nephron-specific Manner*

J. Wade, P. Welling, E. Delpire, 2012, The Journal of Biological Chemistry.

Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.

P. Welling, E. Delpire, R. Coleman, 2017, Journal of the American Society of Nephrology : JASN.

WNKs on the Fly.

P. Welling, 2018, Journal of the American Society of Nephrology : JASN.

Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice

A. Burlingame, D. Bredt, P. Welling, 2007, The Journal of cell biology.

Molecular mechanisms of membrane polarity in renal epithelial cells.

P. Welling, D. Yoo, C. Campo, 2005, Reviews of physiology, biochemistry and pharmacology.

Molecular Mechanisms of Protein Sorting in Polarized Epithelial Cells

P. Welling, B. Ortega, 2012 .

Low Salt Delivery Triggers Autocrine Release of Prostaglandin E2 From the Aldosterone-Sensitive Distal Nephron in Familial Hyperkalemic Hypertension Mice

P. Welling, E. Delpire, P. Grimm, 2022, Frontiers in Physiology.

Roles and Regulation of Renal K Channels.

P. Welling, 2016, Annual review of physiology.

Sulfonylurea-sensitive K(+) transport is involved in Cl(-) secretion and cyst trowth by cultured ADPKD cells.

P. Welling, R. Maser, D. Wallace, 2002, Journal of the American Society of Nephrology : JASN.

NBCe1-A is Required for the Renal Ammonia and Potassium Response to Hypokalemia.

M. Romero, P. Welling, C. Wingo, 2019, American journal of physiology. Renal physiology.

Mechanism of Hyperkalemia-Induced Metabolic Acidosis.

P. Welling, E. Delpire, J. Verlander, 2018, Journal of the American Society of Nephrology : JASN.

Regulation of renal potassium secretion: molecular mechanisms.

P. Welling, 2013, Seminars in nephrology.

Renal sodium and magnesium reabsorption are not coupled in a mouse model of Gordon syndrome

P. Welling, J. van der Wijst, P. Grimm, 2018, Physiological reports.

&agr;-Ketoglutarate drives electroneutral NaCl reabsorption in intercalated cells by activating a G-protein coupled receptor, Oxgr1

P. Welling, P. Grimm, 2017, Current opinion in nephrology and hypertension.

Evidence For and Against Direct Kidney Infection by SARS-CoV-2 in Patients with COVID-19.

P. Welling, D. Batlle, M. Sparks, 2021, Clinical journal of the American Society of Nephrology : CJASN.

Acute Kidney Injury in COVID-19: Emerging Evidence of a Distinct Pathophysiology.

P. Welling, D. Batlle, M. Soler, 2020, Journal of the American Society of Nephrology : JASN.

Impairs Angiogenesis NEU 1 Sialidase Regulates the Sialylation State of CD 31 and Disrupts CD 31-Driven Capillary-Like Tube Formation in Human Lung Microvascular

A. Passaniti, P. Welling, H. DeLisser, 2014 .

The ARH adaptor protein regulates endocytosis of the ROMK potassium secretory channel in mouse kidney.

J. Wade, P. Welling, Bo-young Kim, 2009, The Journal of clinical investigation.

A Phosphorylation-dependent Export Structure in ROMK (Kir 1.1) Channel Overrides an Endoplasmic Reticulum Localization Signal*

P. Welling, Bo-young Kim, D. Yoo, 2005, Journal of Biological Chemistry.

Evidence for endocytosis of ROMK potassium channel via clathrin-coated vesicles.

P. Welling, Chou-Long Huang, V. Babich, 2002, American journal of physiology. Renal physiology.

ROMK and Bartter Syndrome Type 2

P. Welling, 2020, Studies of Epithelial Transporters and Ion Channels.

Two channels for one job.

P. Welling, S. Sansom, Steven C. Sansom, 2007, Kidney international.

A Tandem Di-hydrophobic Motif Mediates Clathrin-dependent Endocytosis via Direct Binding to the AP-2 ασ2 Subunits*

P. Welling, A. Mason, B. Ortega, 2012, The Journal of Biological Chemistry.

AP-2-dependent Internalization of Potassium Channel Kir2.3 Is Driven by a Novel Di-hydrophobic Signal*

P. Welling, A. Mason, Brandiese E Jacobs, 2008, Journal of Biological Chemistry.

Assembly and Trafficking of a Multiprotein ROMK (Kir 1.1) Channel Complex by PDZ Interactions*

P. Welling, T. Flagg, J. Foskett, 2004, Journal of Biological Chemistry.

Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK.

S. Shenolikar, J. Wade, P. Welling, 2001, American journal of physiology. Cell physiology.

ATP is a coupling modulator of parallel Na,K-ATPase-K-channel activity in the renal proximal tubule.

G. Giebisch, P. Welling, K. Tsuchiya, 1992, Proceedings of the National Academy of Sciences of the United States of America.

A Common Signal Patch Drives AP-1 Protein-dependent Golgi Export of Inwardly Rectifying Potassium Channels*

P. Welling, Bo-young Kim, B. Ortega, 2016, The Journal of Biological Chemistry.

A Common Signal Patch Drives AP-1 Dependent Golgi Export of Inwardly Rectifying Potassium Channels

P. Welling, B. Ortega, Xiangming Li, 2016 .

Regulation of potassium channel trafficking in the distal nephron

P. Welling, 2013, Current opinion in nephrology and hypertension.

Hypertension resistance polymorphisms in ROMK (Kir1.1) alter channel function by different mechanisms.

P. Welling, Liang Fang, Dimin Li, 2010, American journal of physiology. Renal physiology.

Processing and transport of ROMK1 channel is temperature-sensitive.

P. Welling, J. Mérot, S. Le Maout, 1999, Biochemical and biophysical research communications.

In Primary Aldosteronism Acute Potassium Chloride Supplementation Suppresses Abundance and Phosphorylation of the Sodium-Chloride Cotransporter

P. Welling, R. Fenton, M. Stowasser, 2022, Kidney360.

Does the early aldosterone‐induced SGK1 play a role in early Kaliuresis?

P. Welling, O. Staub, L. Al-Qusairi, 2022, Physiological reports.

Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney.

D. Bredt, J. Wade, P. Welling, 2005, American journal of physiology. Renal physiology.

Regulation of potassium channel Kir 1.1 (ROMK) abundance in the thick ascending limb of Henle's loop.

G. H. Kim, Gnana Bharathy, J. Wade, 2001, Journal of the American Society of Nephrology : JASN.

Cross-talk and the role of KATP channels in the proximal tubule.

P. Welling, 1995, Kidney international.

α-Ketoglutarate stimulates pendrin-dependent Cl- absorption in the mouse CCD through protein kinase C.

P. Welling, S. Wall, Yoskaly Lazo-Fernandez, 2018, American journal of physiology. Renal physiology.

Rigor before speculation in COVID-19 therapy

P. Welling, D. Batlle, J. B. Byrd, 2020, American journal of physiology. Lung cellular and molecular physiology.

Lin-7 targets the Kir 2.3 channel on the basolateral membrane via a L27 domain interaction with CASK.

P. Welling, Bo-young Kim, C. Alewine, 2007, American journal of physiology. Cell physiology.

Protein and Vesicle Trafficking , Cytoskeleton Lin-7 targets the Kir 2 . 3 channel on the basolateral membrane via a L 27 domain interaction with CASK

P. Welling, Bo-young Kim, C. Alewine, 2007 .

SPAK-mediated NCC regulation in response to low-K+ diet.

J. Wade, P. Welling, E. Delpire, 2015, American journal of physiology. Renal physiology.

Integrated compensatory network is activated in the absence of NCC phosphorylation.

J. Wade, P. Welling, E. Delpire, 2015, The Journal of clinical investigation.

Toward an understanding of hypertension resistance.

A. Subramanya, P. Welling, 2011, American journal of physiology. Renal physiology.

Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species‐specific regulation of blood pressure

P. Welling, Y. C. Chang, P. Grimm, 2020, Physiological reports.

Short Forms of Ste20-related Proline/Alanine-rich Kinase (SPAK) in the Kidney Are Created by Aspartyl Aminopeptidase (Dnpep)-mediated Proteolytic Cleavage*

W. McDonald, P. Welling, E. Delpire, 2014, The Journal of Biological Chemistry.

A Novel Ste20-related Proline/Alanine-rich Kinase (SPAK)-independent Pathway Involving Calcium-binding Protein 39 (Cab39) and Serine Threonine Kinase with No Lysine Member 4 (WNK4) in the Activation of Na-K-Cl Cotransporters*

P. Welling, E. Delpire, Nicolas Markadieu, 2014, The Journal of Biological Chemistry.

Multigene kinase network, kidney transport, and salt in essential hypertension.

J. Wade, P. Welling, Y. C. Chang, 2010, Kidney international.

Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney

P. Welling, D. Ellison, E. Delpire, 2021, Journal of the American Society of Nephrology : JASN.

The endosomal trafficking factors CORVET and ESCRT suppress plasma membrane residence of the renal outer medullary potassium channel (ROMK)

A. Subramanya, P. Welling, J. Brodsky, 2018, The Journal of Biological Chemistry.

Rare mutations in renal sodium and potassium transporter genes exhibit impaired transport function

P. Welling, 2014, Current opinion in nephrology and hypertension.

Identification of compound heterozygous KCNJ1 mutations (encoding ROMK) in a kindred with Bartter's syndrome and a functional analysis of their pathogenicity

P. Welling, J. Sayer, K. Wood, 2013, Physiological reports.

Heterozygous Disruption of Renal Outer Medullary Potassium Channel in Rats Is Associated With Reduced Blood Pressure

J. Wade, P. Welling, J. Levorse, 2013, Hypertension.

The single-cell transcriptomic landscape of early human diabetic nephropathy

Sushrut S. Waikar, S. Waikar, P. Welling, 2019, Proceedings of the National Academy of Sciences.

Novel Subunit Composition of a Renal Epithelial KATPChannel*

P. Welling, W. Lederer, D. Schulze, 1998, The Journal of Biological Chemistry.

Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

E. Olson, P. Welling, S. Seliger, 2021, bioRxiv.

The single-cell transcriptomic landscape of early human diabetic nephropathy

Sushrut S. Waikar, S. Waikar, P. Welling, 2019, Proceedings of the National Academy of Sciences.

TIP-1 has PDZ scaffold antagonist activity.

J. Wade, P. Welling, O. Olsen, 2006, Molecular biology of the cell.

Golgi Export of the Kir2.1 Channel Is Driven by a Trafficking Signal Located within Its Tertiary Structure

P. Welling, W. Lederer, B. Ortega, 2011, Cell.

Renal and colonic potassium transporters in the pregnant rat.

P. Welling, K. Cheng, J. Verlander, 2018, American journal of physiology. Renal physiology.

Mutations affecting the conserved acidic WNK1 motif cause inherited hyperkalemic hyperchloremic acidosis.

P. Welling, X. Jeunemaître, G. Gamba, 2020, The Journal of clinical investigation.

Critical role of the mineralocorticoid receptor in aldosterone-dependent and aldosterone-independent regulation of ENaC in the distal nephron.

P. Welling, J. Canonica, E. Hummler, 2021, American journal of physiology. Renal physiology.

ESCRT regulates surface expression of the Kir2.1 potassium channel

P. Welling, J. Brodsky, Alexander R. Kolb, 2014, Molecular biology of the cell.

Doxycycline Changes the Transcriptome Profile of mIMCD3 Renal Epithelial Cells

P. Welling, O. Woodward, Hyun Jun Jung, 2021, Frontiers in Physiology.

Viewing Cortical Collecting Duct Function Through Phenotype-guided Single-Tubule Proteomics

Markus M. Rinschen, T. Benzing, P. Welling, 2020, Function.

Sound Science before Quick Judgement Regarding RAS Blockade in COVID-19.

L. Tomlinson, P. Welling, D. Batlle, 2020, Clinical journal of the American Society of Nephrology : CJASN.

Phosphatidylinositol 4-Phosphate 5-Kinase Reduces Cell Surface Expression of the Epithelial Sodium Channel (ENaC) in Cultured Collecting Duct Cells*

John P. Johnson, P. Welling, O. Weisz, 2007, Journal of Biological Chemistry.

Proteins Associated with Risk of Kidney Function Decline in the General Population

E. Boerwinkle, N. Chatterjee, J. Coresh, 2021, Journal of the American Society of Nephrology : JASN.

Molecular mechanism of a COOH‐terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation

M. Romero, P. Welling, T. Flagg, 2002, The Journal of physiology.

Scaffolding Proteins in Transport Regulation

P. Welling, 2013 .

CHAPTER 12 – Scaffolding Proteins in Transport Regulation

P. Welling, 2008 .

Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex.

J. Wade, P. Welling, O. Olsen, 2002, American journal of physiology. Cell physiology.

Effect of barium on cell volume regulation in rabbit proximal straight tubules.

P. Welling, M. Linshaw, L. Sullivan, 1985, The American journal of physiology.

Importance of anion in hypotonic volume regulation of rabbit proximal straight tubule.

P. Welling, M. Linshaw, 1988, The American journal of physiology.

A Mutation Linked with Bartter's Syndrome Locks Kir 1.1a (Romk1) Channels in a Closed State

P. Welling, T. Flagg, M. Tate, 1999, The Journal of general physiology.

Primary structure and functional expression of a cortical collecting duct Kir channel.

P. Welling, 1997, American journal of physiology. Renal physiology.

Primary structure and functional expression of a cortical collecting duct Kir channel.

P. Welling, 1997, American journal of physiology. Renal physiology.

Cell swelling activates basolateral membrane Cl and K conductances in rabbit proximal tubule.

P. Welling, R. O'neil, 1990, The American journal of physiology.

Ionic conductive properties of rabbit proximal straight tubule basolateral membrane.

P. Welling, R. O'neil, 1990, The American journal of physiology.

A Tandem Di-hydrophobic Motif Mediates Clathrin-dependent Endocytosis via Direct Binding to the AP-2 (cid:1)(cid:2) 2 Subunits

P. Welling, A. Mason, B. Ortega, 2020 .

Basolateral membrane expression of a K+ channel, Kir 2.3, is directed by a cytoplasmic COOH-terminal domain

P. Welling, J. Mérot, S. Le Maout, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland.

P. Welling, T. Flagg, K A Gregerson, 2001, Endocrinology.

Aldosterone-mediated Na/K-ATPase expression is alpha 1 isoform specific in the renal cortical collecting duct.

P. Welling, M. Sutters, M. Caplan, 1993, The Journal of biological chemistry.

GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD

A. Ewald, P. Welling, T. Watnick, 2020, Journal of Cell Science.

Long‐term kidney function and survival in recipients of allografts from living kidney donors with hypertension: a national cohort study

B. Caffo, P. Welling, D. Segev, 2021, Transplant international : official journal of the European Society for Organ Transplantation.

NEU1 Sialidase Regulates the Sialylation State of CD31 and Disrupts CD31-driven Capillary-like Tube Formation in Human Lung Microvascular Endothelia*

A. Passaniti, P. Welling, H. DeLisser, 2014, The Journal of Biological Chemistry.

Autosomal dominant PKD gets an atomic map

P. Welling, 2018, Nature Reviews Nephrology.

Inhibition of CLC-2 chloride channel expression interrupts expansion of fetal lung cysts.

P. Welling, C. Blaisdell, M. Morales, 2004, American journal of physiology. Lung cellular and molecular physiology.

Phosphorylation‐dependent regulation of NCC is blunted in SPAK null mice (SPAK−/−)

J. Wade, P. Welling, E. Delpire, 2011 .

An Antisense Oligonucleotide Against H1 Inhibits the Classical Sodium Current but not ICa(TTX) in Rat Ventricular Cells

L. Goldman, P. Welling, S. McCulle, 2003, The Journal of physiology.

Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage

E. Boerwinkle, N. Chatterjee, J. Coresh, 2023, Genome Biology.

Acute Intravenous NaCl and Volume Expansion Reduces Sodium-Chloride Cotransporter Abundance and Phosphorylation in Urinary Extracellular Vesicles

P. Welling, R. Fenton, M. Stowasser, 2022, Kidney360.

GDNF drives rapid tubule morphogenesis in novel 3D in vitro model for ADPKD.

A. Ewald, P. Welling, T. Watnick, 2020, Journal of cell science.

Golgin-97 Targets Ectopically Expressed Inward Rectifying Potassium Channel, Kir2.1, to the trans-Golgi Network in COS-7 Cells

P. Welling, B. Y. Kim, Donghui Ma, 2018, Front. Physiol..

Basolateral membrane targeting of a renal-epithelial inwardly rectifying potassium channel from the cortical collecting duct, CCD-IRK3, in MDCK cells.

P. Welling, O. Olsen, J. Mérot, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Dissociation of sodium-chloride cotransporter expression and blood pressure during chronic high dietary potassium supplementation

P. Welling, E. Hoorn, R. Fenton, 2023, JCI insight.

Pendrin null mice develop severe hypokalemia following dietary K+ restriction: role of ENaC.

P. Welling, J. Verlander, J. Loffing, 2022, American journal of physiology. Renal physiology.

A new twist on hypertension-causing mutations in the epithelial Na+ channel.

P. Welling, 2002, Journal of hypertension.

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling

Victor G. Puelles, P. Welling, D. Ellison, 2018, Cell reports.

From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.

Sanjiv J. Shah, J. O’Connell, A. Chakravarti, 2009, Proceedings of the National Academy of Sciences of the United States of America.