J. Wierda

发表

Biphasic EEG changes in relation to loss of consciousness during induction with thiopental, propofol, etomidate, midazolam or sevoflurane.

K. Kuizenga, J. Wierda, C. Kalkman, 2001, British journal of anaesthesia.

Pharmacodynamic behaviour of vecuronium in primary hyperparathyroidism

J. Wierda, E. Roupie, E. Roland, 1994, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

Increased Sensitivity to Vecuronium in Patients with Chronic Renal Failure

R. Henning, J. Wierda, P. Deyn, 1993 .

The pharmacodynamics and pharmacokinetics of Org 9426, a new non-depolarizing neuromuscular blocking agent, in patients anaesthetized with nitrous oxide, halothane and fentanyl

J. Wierda, S. Ágoston, U. Kleef, 1991, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

Pharmacokinetics and Neuromuscular Blocking Effects of Atracurium Besylate and Two of Its Metabolites in Patients with Normal and Impaired Renal Function

J. Wierda, S. Ágoston, R. H. Vandenbrom, 1990, Clinical pharmacokinetics.

Clinical observations on the neuromuscular blocking action of Org 9426, a new steroidal non-depolarizing agent.

K. Kuizenga, J. Wierda, S. Ágoston, 1990, British journal of anaesthesia.

Twitch Potentiation Influences the Time Course of Twitch Depression in Muscle Relaxant Studies: A Pharmacokinetic-Pharmacodynamic Explanation

J. Proost, J. Wierda, D. Eleveld, 2006, Journal of Pharmacokinetics and Pharmacodynamics.

A Pharmacokinetic–Pharmacodynamic Model for Neuromuscular Blocking Agents to Predict Train-of-Four Twitches

J. Proost, J. Wierda, D. Eleveld, 2003, Journal of Pharmacokinetics and Pharmacodynamics.

Dose-response and concentration-response relation of rocuronium infusion during propofol-nitrous oxide and isoflurane-nitrous oxide anaesthesia.

J. Wierda, K. Olkkola, M. Kansanaho, 1997, European journal of anaesthesiology.

Structure-pharmacokinetic and pharmacodynamic relationships of steroidal neuromuscular blocking agents

J. Proost, J. Wierda, D. Meijer, 1995 .

The isolated heart-lung preparation in the cat. An in situ model to study the role of the lungs in the disposition of drugs.

J. Wierda, M. Houwertjes, U. Kleef, 1993, Journal of pharmacological and toxicological methods.

Pancuronium bromide in the intensive care unit: a case of overdose.

J. Wierda, R. H. Vandenbrom, 1988, Anesthesiology.

Dose‐response relationship and time course of action of Org 9426

J. Wierda, P. Hennis, S. Ágoston, 1991, Anaesthesia.

Post-sucdnylcholine muscle pain and smoking

J. Wierda, V. Nigrović, 1994, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

Pharmacokinetic/Pharmacodynamic Modeling of Rocuronium in Myasthenic Patients Is Improved by Taking into Account the Number of Unbound Acetylcholine Receptors

J. Proost, J. Wierda, A. de Haes, 2002, Anesthesia and analgesia.

The influence of hypothermia (surface cooling) on the time-course of action and on the pharmacokinetics of rocuronium in humans.

P. J. Nederveen, J. Wierda, S. Ágoston, 1995, European journal of anaesthesiology. Supplement.

Early Reversal of Profound Rocuronium-induced Neuromuscular Blockade by Sugammadex in a Randomized Multicenter Study: Efficacy, Safety, and Pharmacokinetics

J. Proost, J. Wierda, V. Saldien, 2007, Anesthesiology.

Clinical Pharmacokinetics of Neuromuscular Blocking Drugs

J. Wierda, S. Ágoston, R. H. Vandenbrom, 1992, Clinical pharmacokinetics.

Hypothermic cardiopulmonary bypass influences the concentration-response relationship and the biodisposition of rocuronium.

J. Wierda, P. Hennis, R. C. G. Gallandat Huet, 1995, European Journal of Anaesthesiology - Supplement.

Effects of hypothermic cardiopulmonary bypass on the pharmacodynamics and pharmacokinetics of rocuronium.

J. Wierda, P. Hennis, J. Wierda, 1995, Journal of cardiothoracic and vascular anesthesia.

Transient nerve damage following intubation for trans-sphenoidal hypophysectomy

J. Wierda, G. B. Eindhoven, K. Evers, 1999, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

Do Plasma Concentrations Obtained from Early Arterial Blood Sampling Improve Pharmacokinetic/Pharmacodynamic Modeling?

J. Proost, K. Kuizenga, J. Wierda, 1999, Journal of Pharmacokinetics and Biopharmaceutics.

A Temporary Decrease in Twitch Response During Reversal of Rocuronium-Induced Muscle Relaxation with a Small Dose of Sugammadex

J. Proost, K. Kuizenga, J. Wierda, 2007, Anesthesia and analgesia.

An Isolated, Antegrade, Perfused, Peroneal Nerve Anterior Tibialis Muscle Model in the Rat: A Novel Model Developed to Study the Factors Governing the Time Course of Action of Neuromuscular Blocking Agents

J. Proost, J. Wierda, A. de Haes, 2002, Anesthesiology.

Inhibition of the Enzymic Degradation of Suxamethonium and Mivacurium Increases the Onset Time of Submaximal Neuromuscular Block

J. Proost, J. Wierda, M. Houwertjes, 1998, Anesthesiology.

Clinical pharmacology of rocuronium (Org 9426): study of the time course of action, dose requirement, reversibility, and pharmacokinetics.

J. Wierda, P. Hennis, M. Leclercq, 1994, Journal of clinical anesthesia.

Time Course of Action and Endotracheal Intubating Conditions of Org 9487, a New Short‐Acting Steroidal Muscle Relaxant; A Comparison with Succinylcholine

K., J. Proost, J. Wierda, 1993, Anesthesia and analgesia.

Preliminary investigations of the clinical pharmacology of three short-acting non-depolarizing neuromuscular blocking agents, Org 9453, Org 9489 and Org 9487

J. Wierda, S. Ágoston, U. Kleef, 1994, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

Time course of action and intubating conditions following vecuronium, rocuronium and mivacurium

J. Wierda, F. Hommes, H. Nap, 1995, Anaesthesia.

Pharmacodynamics and pharmacokinetics of an infusion of Org 9487, a new short-acting steroidal neuromuscular blocking agent.

J. Proost, J. Wierda, L. van den Broek, 1994, British journal of anaesthesia.

Design of drugs for rapid onset

J. Proost, J. Wierda, R. Marshall, 1993 .

Is time to peak effect of neuromuscular blocking agents dependent on dose? Testing the concept of buffered diffusion

J. Proost, J. Wierda, M. Houwertjes, 2008, European journal of anaesthesiology.

An extended pharmacokinetic/pharmacodynamic model describing quantitatively the influence of plasma protein binding, tissue binding, and receptor binding on the potency and time course of action of drugs

J. Proost, J. Wierda, D. Meijer, 1996, Journal of Pharmacokinetics and Biopharmaceutics.

Clinical pharmacology of ORG 7617, a short-acting non-depolarizing neuromuscular blocking agent

J. Proost, J. Wierda, S. Ágoston, 2004, European Journal of Clinical Pharmacology.

Dose‐Response Relation, Neuromuscular Blocking Action, Intubation Conditions, and Cardiovascular Effects of Org 9273, a New Neuromuscular Blocking Agent

J. Wierda, L. V. den Broek, F. Richardson, 1991, Anesthesia and analgesia.

The pharmacokinetics, urinary and biliary excretion of pipecuronium bromide.

J. Wierda, S. Ágoston, U. Kleef, 1991, European journal of anaesthesiology.

Dose‐Response Relation and Time Course of Action of Pipecuronium Bromide in Humans Anesthetized with Nitrous Oxide and Isoflurane, Halothane, or Droperidol and Fentanyl

J. Wierda, S. Ágoston, F. Richardson, 1989, Anesthesia and analgesia.

Pharmacokinetics and pharmacodynamics of rocuronium at the vocal cords and the adductor pollicis in humans

J H Proost, B Plaud, C. Meistelman, 1995, Clinical pharmacology and therapeutics.

Current developments in anaesthesia and neuromuscular transmission.

J. Wierda, R. Mirakhur, 2001, European Journal of Anaesthesiology - Supplement.

EARLY REVERSIBILITY OF ORG 9487, A NEW STEROIDAL MUSCLE RELAXANT

J. Wierda, S. Ágoston, N. Smeulers, 1992 .

Cardiovascular effects of an intubating dose of rocuronium 0.6 mg kg-1 in anaesthetized patients, paralysed with vecuronium.

J. Wierda, M. Schuringa, L. van den Broek, 1997, British journal of anaesthesia.

Haemodynamic effects of vecuronium.

J. Wierda, H. Lip, S. Ágoston, 1989, British journal of anaesthesia.

Rocuronium- and mivacurium-induced neuromuscular block and intubating conditions: a comparison with vecuronium.

J. Wierda, F. Hommes, L. van den Broek, 1995, European Journal of Anaesthesiology - Supplement.

Potency and onset of action of neuromuscular blocking drugs.

J. Wierda, S. Schiere, E. Maestrone, 1995, Anesthesia and analgesia.

Neuromuscular and cardiovascular effects of neostigmine and methyl-atropine administered at different degrees of rocuronium-induced neuromuscular block.

J. Proost, J. Wierda, P. Hennis, 1994, European journal of anaesthesiology.

Pharmacokinetic–Pharmacodynamic Modeling of Rocuronium in Case of a Decreased Number of Acetylcholine Receptors: A Study in Myasthenic Pigs

J. Proost, J. Wierda, A. de Haes, 2003, Anesthesiology.

Predictability of Processed Electroencephalography Effects on the Basis of Pharmacokinetic–Pharmacodynamic Modeling during Repeated Propofol Infusions in Patients with Extradural Analgesia

J. Proost, K. Kuizenga, J. Wierda, 2001, Anesthesiology.

Effect of Hypothermia on the Hepatic Uptake and Biliary Excretion of Vecuronium in the Isolated Perfused Rat Liver

J. Proost, J. Maring, J. Wierda, 2001, Anesthesiology.

Relationship between Chemical Structure and Physicochemical Properties of Series of Bulky Organic Cations and Their Hepatic Uptake and Biliary Excretion Rates 1

J. Proost, J. Wierda, D. Meijer, 1997 .

Improving Pharmacokinetic–Pharmacodynamic Models of Muscle Relaxants Using Potentiation Modelling

J. Proost, J. Wierda, D. Eleveld, 2005, Journal of Pharmacokinetics and Pharmacodynamics.

Pharmacokinetics and disposition of pipecuronium bromide in the cat.

J. Wierda, M. Houwertjes, S. Ágoston, 1988, European journal of anaesthesiology.

CORRELATION BETWEEN PHYSICO-CHEMICAL PROPERTIES AND PHARMACOKINETIC AND DYNAMIC PARAMETERS OF MUSCLE RELAXANTS

J. Proost, J. Wierda, D. Meijer, 1992 .

A901 EFFECTS OF HYPERPARATHYROIDISM ON THE VECURONIUM-INDUCED NEUROMUSCULAR BLOCKADE

J. Wierda, S. Villiers, C. Dubost, 1990 .

Rapid onset/offset of rapacuronium bromide explained?

J. Proost, J. Wierda, S. Schiere, 1999, Anesthesiology.

Vecuronium and rocuronium

J. Wierda, P. Hennis, L. Broek, 1993, Anaesthesia.

Hemodynamic Effects of Vecuronium

J. Wierda, H. Lip, S. Ágoston, 1989 .

Steroidal neuromuscular blocking agents

J. Wierda, 1998 .

Structure-pharmacodynamic-pharmacokinetic relationships of steroidal neuromuscular blocking agents.

J. Proost, J. Wierda, J. Wierda, 1995, European journal of anaesthesiology. Supplement.

Time course of neuromuscular effects and pharmacokinetics of rocuronium bromide (Org 9426) during isoflurane anaesthesia in patients with and without renal failure.

J. Wierda, R. Mirakhur, J. Wierda, 1993, British journal of anaesthesia.

Pharmacokinetics of rocuronium after bolus and continuous infusion during halothane anaesthesia.

J. Proost, J. Wierda, R. Mirakhur, 1996, British journal of anaesthesia.

Determination of rocuronium and its putative metabolites in body fluids and tissue homogenates.

J. Proost, J. Wierda, J. Wierda, 1993, Journal of chromatography.

Evaluation of a Closed-Loop Muscle Relaxation Control System

J. Proost, J. Wierda, D. Eleveld, 2005, Anesthesia and analgesia.