J. Gesell

发表

Flexible lid to the p53-binding domain of human Mdm2: Implications for p53 regulation

M. McCoy, J. Gesell, M. Senior, 2003, Proceedings of the National Academy of Sciences of the United States of America.

In Vitro Assays for the Discovery of PCSK9 Autoprocessing Inhibitors

J. Gesell, Shirly Pinto, M. Kavana, 2016, Journal of biomolecular screening.

NMR structure of the principal neutralizing determinant of HIV-1 displayed in filamentous bacteriophage coat protein.

J. Gesell, R. Perham, S. Opella, 1997, Journal of molecular biology.

The roles of homonuclear line narrowing and the1H amide chemical shift tensor in structure determination of proteins by solid-state NMR spectroscopy

J. Gesell, Che Ma, S. Opella, 1999 .

A simple protocol for identification of helical and mobile residues in membrane proteins.

M. Klein, D. Tobias, J. Gesell, 1995, Journal of molecular biology.

Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.

W. Shipe, H. Su, J. Gesell, 2016, ACS medicinal chemistry letters.

Discovery of an irreversible HCV NS5B polymerase inhibitor.

J. Gesell, J. Duca, F. G. Njoroge, 2013, Bioorganic & medicinal chemistry letters.

Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction.

Yaolin Wang, J. Gesell, Yaolin Wang, 2004, Analytical biochemistry.

Two-dimensional 1H NMR experiments show that the 23-residue magainin antibiotic peptide is an α-helix in dodecylphosphocholine micelles, sodium dodecylsulfate micelles, and trifluoroethanol/water solution

J. Gesell, S. Opella, Jennifer Gesell, 1997, Journal of biomolecular NMR.

Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase.

J. Gesell, D. Wyss, D. Liu, 2001, Journal of Molecular Biology.

Design, high-level expression, purification and characterization of soluble fragments of the hepatitis C virus NS3 RNA helicase suitable for NMR-based drug discovery methods and mechanistic studies.

J. Gesell, D. Wyss, P. C. Weber, 2001, Protein engineering.

Solution structure and dynamics of the single-chain hepatitis C virus NS3 protease NS4A cofactor complex.

J. Gesell, M. Senior, D. Wyss, 2001, Journal of molecular biology.

Orientations of amphipathic helical peptides in membrane bilayers determined by solid-state NMR spectroscopy

J. Gesell, S. Opella, J. Tomich, 1991, Journal of biomolecular NMR.

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy

J. Gesell, S. Opella, A. Valente, 1999, Nature Structural Biology.

Dilute spin-exchange assignment of solid-state NMR spectra of oriented proteins: Acetylcholine M2 in bilayers

J. Gesell, S. Opella, A. Valente, 1999, Journal of biomolecular NMR.

Three-dimensional solid-state NMR spectroscopy is essential for resolution of resonances from in-plane residues in uniformly (15)N-labeled helical membrane proteins in oriented lipid bilayers.

J. Gesell, S. Opella, F. Marassi, 2000, Journal of magnetic resonance.

Recent Developments in Multidimensional NMR Methods for Structural Studies of Membrane Proteins

J. Gesell, S. Opella, F. Marassi, 2002 .