I. Condò

发表

Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia

N. Toschi, Giulia Alfedi, Riccardo Luffarelli, 2019, Movement disorders : official journal of the Movement Disorder Society.

Acetylation Suppresses the Proapoptotic Activity of GD3 Ganglioside

I. Condò, F. Malisan, R. Testi, 2002, The Journal of experimental medicine.

Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells

I. Condò, D. S. Massaro, M. Benini, 2015, Neurobiology of Disease.

Src kinase phosphorylates Caspase‐8 on Tyr380: a novel mechanism of apoptosis suppression

G. Superti-Furga, I. Condò, R. Testi, 2006, The EMBO journal.

Sensitivity of Neuroimaging Indicators in Monitoring the Effects of Interferon Gamma Treatment in Friedreich’s Ataxia

N. Toschi, R. Salati, I. Condò, 2020, Frontiers in Neuroscience.

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

E. Cundari, I. Condò, R. Testi, 2008, Blood.

E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia

Nicola Toschi, N. Toschi, Giulia Alfedi, 2017, Cell reports.

Preventing the ubiquitin-proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia.

I. Condò, S. Fortuni, D. Serio, 2011, Human molecular genetics.

A caspaselike activity is triggered by LPS and is required for survival of human dendritic cells.

I. Condò, R. Testi, C. Nicoló, 2003, Blood.

GD3 ganglioside directly targets mitochondria in a bcl‐2‐controlled fashion

M. Todaro, G. Kroemer, I. Condò, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Drug Repositioning in Friedreich Ataxia

I. Condò, F. Malisan, R. Testi, 2022, Frontiers in Neuroscience.

Caspase-Dependent Cleavage of c-Abl Contributes to Apoptosis

G. Superti-Furga, I. Condò, R. Testi, 2003, Molecular and Cellular Biology.

Analysis of intracellular distribution and apoptosis involvement of the Ufd1l gene product by over‐expression studies

I. Condò, R. Testi, B. Dallapiccola, 2003, Cell biochemistry and function.

Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model

I. Condò, S. Fortuni, F. Malisan, 2012, Human molecular genetics.

A Pool of Extramitochondrial Frataxin That Promotes Cell Survival*

I. Condò, F. Malisan, R. Testi, 2006, Journal of Biological Chemistry.

Frataxin deficiency in Friedreich's ataxia is associated with reduced levels of HAX-1, a regulator of cardiomyocyte death and survival.

N. Toschi, Giulia Alfedi, Riccardo Luffarelli, 2020, Human molecular genetics.

SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia

Piero Carninci, S. Gustincich, Riccardo Luffarelli, 2019, Nucleic acids research.

Intracellular mediators of programmed cell death initiated at the cell surface receptor Fas

I. Condò, R. Testi, 2000, Transplant international : official journal of the European Society for Organ Transplantation.

Fibroblast growth factor-2 transiently activates the p53 oncosuppressor protein in human primary vascular smooth muscle cells: implications for atherogenesis.

I. Condò, M. Falchi, G. Barillari, 2010, Atherosclerosis.

In vivo maturation of human frataxin.

I. Condò, F. Malisan, R. Testi, 2007, Human molecular genetics.

Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

I. Condò, D. Serio, F. Malisan, 2010, Human molecular genetics.

Frataxin participates to the hypoxia-induced response in tumors

G. Maira, I. Condò, D. Serio, 2011, Cell Death and Disease.

GD3 ganglioside as an intracellular mediator of apoptosis.

M. Todaro, G. Kroemer, I. Condò, 2000, European cytokine network.

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans

Nektarios Tavernarakis, I. Condò, F. Malisan, 2013, Experimental Gerontology.

Safety and Efficacy Of Interferon γ in Friedreich's Ataxia

N. Toschi, R. Salati, Riccardo Luffarelli, 2020, Movement disorders : official journal of the Movement Disorder Society.

Src inhibitors modulate frataxin protein levels.

I. Condò, S. Fortuni, D. Serio, 2015, Human molecular genetics.

Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans

I. Condò, R. Testi, T. Johnson, 2005, Aging cell.

Interferon Gamma Enhances Cytoprotective Pathways via Nrf2 and MnSOD Induction in Friedreich’s Ataxia Cells

Riccardo Luffarelli, I. Condò, Luca Panarello, 2023, International journal of molecular sciences.

Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin.

I. Condò, F. Malisan, R. Testi, 2010, Human molecular genetics.

Rare Monogenic Diseases: Molecular Pathophysiology and Novel Therapies

I. Condò, 2022, International journal of molecular sciences.