Yiqun Zhang

发表

Comprehensive genomic characterization of squamous cell lung cancers

Steven J. M. Jones, Joshua M. Stuart, Brian D. O’Connor, 2012, Nature.

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Lovelace J. Luquette, L. Chin, J. Weinstein, 2017, Cancer cell.

Pan-urologic cancer genomic subtypes that transcend tissue of origin

Michael Ittmann, Chad J Creighton, Yiqun Zhang, 2017, Nature Communications.

Integrated Analyses of microRNAs Demonstrate Their Widespread Influence on Gene Expression in High-Grade Serous Ovarian Carcinoma

C. Sander, R. Gibbs, P. Spellman, 2012, PloS one.

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.

K. Cibulskis, S. Gabriel, J. Mesirov, 2012, The Journal of clinical investigation.

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

Adrian V. Lee, G. Mills, S. Hilsenbeck, 2010, Breast Cancer Research.

Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130.

A. Sboner, C. Creighton, Yiqun Zhang, 2021, Oncogene.

Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity.

Payam Shahi, C. Creighton, M. Ittmann, 2012, Cell stem cell.

Sensitivity of RECQL4-deficient fibroblasts from Rothmund–Thomson syndrome patients to genotoxic agents

S. Plon, Yiqun Zhang, Hao Liu, 2008, Human Genetics.

Association of medical home care and disparities in emergency care utilization among children with special health care needs.

Yiqun Zhang, Hao Liu, A. Giardino, 2009, Academic pediatrics.

PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis

G. Mills, C. Creighton, Yiqun Zhang, 2020, Nature.

Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

S. Hanash, I. Wistuba, C. Creighton, 2017, Scientific Reports.

Global impact of somatic structural variation on the DNA methylome of human cancers

Lovelace J. Luquette, L. Chin, P. Park, 2019, Genome Biology.

Whole genome and RNA sequencing of 1,220 cancers reveals hundreds of genes deregulated by rearrangement of cis-regulatory elements

Nuno A. Fonseca, A. Brazma, C. Creighton, 2017, bioRxiv.

Diagnosis, Management, and Outcome of Patients with Dedifferentiated Liposarcoma Systemic Metastasis

C. Creighton, A. Lazar, Yiqun Zhang, 2011, Annals of Surgical Oncology.

Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.

W. Birchmeier, C. Creighton, L. True, 2019, Cell stem cell.

Spatially Restricted Strom al Wnt Signaling Restrains Prostate Epithelial Progenitor Growth throughDirect and Indirect Mechanisms Graphical

W. Birchmeier, C. Creighton, L. True, 2019 .

Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways

S. Varambally, C. Creighton, Yiqun Zhang, 2022, Nature Communications.

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Nuno A. Fonseca, Angela N. Brooks, David T. W. Jones, 2020, Nature Communications.

Uterine Leiomyosarcoma Management, Outcome, and Associated Molecular Biomarkers: A Single Institution’s Experience

K. Hunt, C. Creighton, Matthew L. Anderson, 2013, Annals of Surgical Oncology.

Stem Cell Antigen-1 (Sca-1) Regulates Mammary Tumor Development and Cell Migration

C. Creighton, Yiqun Zhang, J. Rosen, 2011, PloS one.

Comprehensive analysis of the expression and prognosis for COL4A family genes in kidney renal clear cell carcinoma

Yiqun Zhang, Bizhi Tu, Laifu Wei, 2021 .

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.

C. Coarfa, C. Creighton, Yiqun Zhang, 2016, Cell reports.

Chemoprevention of BBN-Induced Bladder Carcinogenesis by the Selective Estrogen Receptor Modulator Tamoxifen.

S. Hilsenbeck, Yiqun Zhang, S. Lerner, 2013, Translational oncology.

SPATIALLY-RESTRICTED STROMAL WNT SIGNALING RESTRAINS PROSTATE EPITHELIAL PROGENITOR PROLIFERATION THROUGH DIRECT AND INDIRECT MECHANISMS

Hoang, C. Creighton, L. True, 2019 .

Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34‐positive compartment

C. Creighton, Yiqun Zhang, J. Cortes, 2012, Cancer.

Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis

C. Creighton, T. Liu, Yiqun Zhang, 2022, Cell reports.

Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity

Mary C. Regier, C. Creighton, L. True, 2022, Nature Communications.

Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy

E. Pleasance, M. Marra, Steven J. M. Jones, 2021, Cell reports.

SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints

Chad Creighton, Yiqun Zhang, Fengju Chen, 2021, BMC Bioinformatics.

Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients

C. Creighton, Yiqun Zhang, D. Gibbons, 2014, International journal of cancer.

Functional Heterogeneity of Mouse Prostate Stromal Cells Revealed by Single-Cell RNA-Seq

C. Creighton, Yumei Li, Rui Chen, 2019, iScience.

A gene transcription signature of obesity in breast cancer

C. Creighton, Jenny C. Chang, Yiqun Zhang, 2012, Breast Cancer Research and Treatment.

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression.

Alexander Pertsemlidis, Gregory J Goodall, Chad J Creighton, 2009, Genes & development.

Identification of diverse astrocyte populations and their malignant analogs

Benjamin R Arenkiel, Teng-Wei Huang, Nabil Ahmed, 2017, Nature Neuroscience.

Survivin Is a Viable Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors

C. Creighton, A. Lazar, Yiqun Zhang, 2012, Clinical Cancer Research.

Dual Targeting of mTOR and Aurora-A Kinase for the Treatment of Uterine Leiomyosarcoma

K. Hunt, C. Creighton, Kai Huang, 2012, Clinical Cancer Research.

Pregnancy-Induced Noncoding RNA (PINC) Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation

C. Creighton, Yiqun Zhang, M. Dinger, 2012, PLoS genetics.

Global impact of somatic structural variation on the DNA methylome of human cancers

Lovelace J. Luquette, L. Chin, P. Park, 2019, Genome Biology.

Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.

C. Perou, S. Hilsenbeck, R. Cardiff, 2010, Cancer research.

Molecular Correlates of Metastasis by Systematic Pan-Cancer Analysis Across The Cancer Genome Atlas

S. Varambally, C. Creighton, Yiqun Zhang, 2018, Molecular Cancer Research.

ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis

Jianqiang Mao, Sung-Nam Cho, Francesco J DeMayo, 2015, Cell reports.

ErbB 2 Pathway Activation upon Smad 4 Loss Promotes Lung Tumor Growth and Metastasis Graphical

Jianqiang Mao, Sung-Nam Cho, Nili Jin, 2015 .

Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN

C. Creighton, M. Ittmann, Yiqun Zhang, 2018, Oncotarget.

RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression.

Michael Ittmann, Chad J. Creighton, Yiqun Zhang, 2017, Cancer research.

MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer.

C. Creighton, Patricia D. Castro, M. Ittmann, 2016, Cancer research.

Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases

C. Creighton, M. Ittmann, Yiqun Zhang, 2018, Clinical Cancer Research.

Multiplatform-based Molecular Subtypes of Non-Small Cell Lung Cancer

Yiling Lu, Rehan Akbani, Gordon B. Mills, 2016, Oncogene.

HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome

L. Chin, C. Creighton, Yiqun Zhang, 2013, Oncogene.

Erratum to: Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and Histologic characteristics of human cancers

C. Creighton, Yiqun Zhang, S. Lai, 2014, Journal of Translational Medicine.

Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumors

C. Creighton, Yiqun Zhang, Fengju Chen, 2021, Scientific Reports.

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.

Payam Shahi, C. Creighton, M. Ittmann, 2014, Cancer research.

Recapitulates Human Reactive Stroma Signaling in Prostate Cancer Mouse Models β TGF-− WNT − FGFR 1

Payam Shahi, C. Creighton, M. Ittmann, 2014 .

Tumor and Stem Cell Biology FGFR1–WNT–TGF-b Signaling in Prostate Cancer Mouse Models Recapitulates Human Reactive Stroma

Payam Shahi, C. Creighton, M. Ittmann, 2014 .

FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.

Payam Shahi, C. Creighton, M. Ittmann, 2014, Cancer research.

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Lovelace J. Luquette, L. Chin, P. Park, 2018, Cell reports.

Correction: Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and Histologic characteristics of human cancers

C. Creighton, Yiqun Zhang, S. Lai, 2014, Journal of Translational Medicine.

Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers

S. Varambally, C. Creighton, Yiqun Zhang, 2021, Oncogene.

Genomic rearrangements near genes leading to upregulation across a diverse subset of human cancers

C. Creighton, Yiqun Zhang, Fengju Chen, 2017 .

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.

Chris Sander, Victor Reuter, Yiling Lu, 2016, Cell reports.

Molecular and Cellular Pathobiology Cancer Research Fibroblast Growth Factor Receptor Signaling Dramatically Accelerates Tumorigenesis and Enhances Oncoprotein Translation in the Mouse Mammary Tumor Virus – Wnt-1 Mouse Model of Breast Cancer

C. Perou, S. Hilsenbeck, R. Cardiff, 2010 .

A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

L. Donehower, C. Creighton, Yiqun Zhang, 2021, Nature Communications.

Systematic identification of non-coding somatic single nucleotide variants associated with altered transcription and DNA methylation in adult and pediatric cancers

C. Creighton, Yiqun Zhang, Fengju Chen, 2021, NAR cancer.

Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Nuno A. Fonseca, A. Brazma, C. Creighton, 2022, Nature communications.

The Sca‐1+ and Sca‐1− mouse prostatic luminal cell lineages are independently sustained

C. Creighton, S. Jung, Yiqun Zhang, 2020, Stem cells.

CCAAT/Enhancer Binding Protein Beta Regulates Stem Cell Activity and Specifies Luminal Cell Fate in the Mammary Gland

C. Creighton, Yiqun Zhang, Hao Liu, 2010, Stem cells.

Crosstalk from Non-Cancerous Mitochondria Can Inhibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways

C. Creighton, Yiqun Zhang, Tin-Lap Lee, 2013, PloS one.

Identification of diverse tumor endothelial cell populations in malignant glioma.

Joshua D. Wythe, Alexander M. Herman, C. Creighton, 2020, Neuro-oncology.

Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer.

J. Frasor, Jeanne M. Danes, C. Creighton, 2017, Cancer research.

Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer

C. Creighton, Patricia D. Castro, M. Ittmann, 2023, Epigenetics.

Against Ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis

Yiqun Zhang, Hao Wang, Lei Zhang, 2015, Journal of Zhejiang University-SCIENCE B.

Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.

S. Hilsenbeck, Yiqun Zhang, D. Corry, 2014, The Journal of clinical investigation.

Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema

Chen Dong, Farrah Kheradmand, Xiaoyi Yuan, 2012, Science Translational Medicine.

Pan-cancer molecular subtypes of metastasis reveal distinct and evolving transcriptional programs

C. Creighton, Yiqun Zhang, Fengju Chen, 2023, Cell reports. Medicine.

Macrophages promote the progression of premalignant mammary lesions to invasive cancer

F. Kittrell, S. Fuqua, C. Creighton, 2017, Oncotarget.

Macrophages promote the progression of premalignant mammary lesions to invasive cancer.

F. Kittrell, S. Fuqua, C. Creighton, 2017, Oncotarget.

Stromal TGF-β signaling induces AR activation in prostate cancer

C. Creighton, M. Ittmann, Yiqun Zhang, 2014, Oncotarget.

Ex vivo four-dimensional lung cancer model mimics metastasis.

Michael J. Thrall, C. Creighton, Yiqun Zhang, 2015, Annals of Thoracic Surgery.

miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer

C. Creighton, M. Ittmann, Yiqun Zhang, 2017, Oncotarget.

FGF23 promotes prostate cancer progression

C. Creighton, M. Ittmann, Yiqun Zhang, 2015, Oncotarget.

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis

Michael Ittmann, Li Zhang, Chad J. Creighton, 2015, Oncotarget.

Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.

C. Roehrborn, C. Creighton, Patricia D. Castro, 2016, Molecular cell.

A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis

C. Creighton, M. Ittmann, Yiqun Zhang, 2013, Oncogene.

Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target

R. West, C. Creighton, Shirley X. Zhu, 2011, The Journal of pathology.

Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen.

Yiqun Zhang, R. Krance, K. Leung, 2008, Biology of Blood and Marrow Transplantation.

Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice

C. Creighton, Yiqun Zhang, Yongchao Dou, 2023, Science advances.

Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis

C. Coarfa, C. Creighton, P. Saha, 2020, bioRxiv.

Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers

C. Creighton, Yiqun Zhang, F. Johnson, 2013, Journal of Translational Medicine.

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

Adrian V. Lee, G. Mills, S. Hilsenbeck, 2022 .

Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load

J. Petrosino, G. Metcalf, C. Creighton, 2023, Research square.

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

G. Mills, S. Hilsenbeck, R. Schiff, 2010 .

Against Ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis

Yiqun Zhang, Hao Wang, Lei Zhang, 2015, Journal of Zhejiang University-SCIENCE B.

Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen.

Yiqun Zhang, R. Krance, K. Leung, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN

C. Creighton, M. Ittmann, Yiqun Zhang, 2018, Oncotarget.

Comprehensive genomic characterization of squamous cell lung cancers

Joshua M. Stuart, Brian D. O’Connor, Charles J. Vaske, 2012, Nature.

Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.

C. Roehrborn, C. Creighton, Patricia D. Castro, 2016, Molecular cell.

Global impact of somatic structural variation on the cancer proteome

S. Varambally, Yiqun Zhang, Fengju Chen, 2023, Nature communications.

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

S. Hilsenbeck, R. Schiff, C. Creighton, 2010, Breast Cancer Research.

Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load

R. Gibbs, J. Petrosino, G. Metcalf, 2023, bioRxiv.