P. Higgins

发表

The human gut microbiome: current knowledge, challenges, and future directions.

M. Dave, P. Higgins, S. Middha, 2012, Translational research : the journal of laboratory and clinical medicine.

Noninvasive ultrasound elasticity imaging (UEI) of Crohn's disease: animal model.

C. Jia, J. Rubin, P. Higgins, 2008, Ultrasound in medicine & biology.

Mapping the relationships between inflammatory bowel disease and comorbid diagnoses to identify disease associations

Toby P. Keeney-Bonthrone, D. Hanauer, P. Higgins, 2020, European journal of gastroenterology & hepatology.

Comparison of imputation methods for missing laboratory data in medicine

J. Marrero, P. Higgins, A. Singal, 2013, BMJ Open.

Machine Learning Algorithms Outperform Conventional Regression Models in Predicting Development of Hepatocellular Carcinoma

J. Marrero, A. Lok, P. Higgins, 2013, The American Journal of Gastroenterology.

Algorithms outperform metabolite tests in predicting response of patients with inflammatory bowel disease to thiopurines.

Sijian Wang, P. Higgins, Joel C. Joyce, 2010, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

An organoid and multi-organ developmental cell atlas reveals multilineage fate specification in the human intestine

I. Glass, P. Higgins, B. Treutlein, 2020, bioRxiv.

Performance of a Deep Learning Model vs Human Reviewers in Grading Endoscopic Disease Severity of Patients With Ulcerative Colitis

Ryan W. Stidham, Wenshuo Liu, Akbar K. Waljee, 2019, JAMA network open.

Does colonoscopy cause increased ulcerative colitis symptoms?

Peter Higgins, P. Higgins, S. Korsnes, 2007, Inflammatory bowel diseases.

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

Marc Vandemeulebroecke, Marco Londei, Gervais Tougas, 2012, Gut.

Controversies in ulcerative colitis: a survey comparing decision making of experts versus community gastroenterologists.

S. Targan, M. Dubinsky, B. Spiegel, 2009, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

A new nonlinear parameter in the developed strain-to-applied strain of the soft tissues and its application in ultrasound elasticity imaging.

J. Rubin, P. Higgins, Kang Kim, 2012, Ultrasound in medicine & biology.

Rectal indometacin dose escalation for prevention of pancreatitis after endoscopic retrograde cholangiopancreatography in high-risk patients: a double-blind, randomised controlled trial.

Richard S. Kwon, P. Higgins, S. Sherman, 2019, The lancet. Gastroenterology & hepatology.

Patient defined dichotomous end points for remission and clinical improvement in ulcerative colitis

M. Schwartz, P. Higgins, J. Mapili, 2005, Gut.

Is Endoscopy Necessary for the Measurement of Disease Activity in Ulcerative Colitis?

M. Schwartz, P. Higgins, J. Mapili, 2005, The American Journal of Gastroenterology.

Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: Impact of a “Top‐Down” approach to intestinal fibrosis in mice

A. Luke, P. Higgins, L. Johnson, 2012, Inflammatory bowel diseases.

Statins and the risk of colorectal cancer.

Ronit Almog, Stephen B Gruber, Gad Rennert, 2005, The New England journal of medicine.

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD With the European Crohn's and Colitis Organization: When to Start, When to Stop, Which Drug to Choose, and How to Predict Response?

S. Schreiber, S. Vermeire, D. Hommes, 2011, The American Journal of Gastroenterology.

The Impact of Raising the Bar for Clinical Trials in Ulcerative Colitis

P. Higgins, B. Sands, C. Nduaka, 2019, Journal of Crohn's & colitis.

Impact of Quality Improvement Educational Interventions on Documented Adherence to Quality Measures for Adults with Crohn's Disease

P. Higgins, B. Patel, K. Moreo, 2015, Inflammatory bowel diseases.

The epidemiology of ischaemic colitis

L. Laine, P. Higgins, K. Davis, 2004, Alimentary pharmacology & therapeutics.

Magnetic resonance enterography is feasible and reliable in multicenter clinical trials in patients with Crohn's disease, and may help select subjects with active inflammation

P. Rutgeerts, S. Vermeire, C. Santillan, 2016, Alimentary pharmacology & therapeutics.

Editorial: Characterization of Inflammation and Fibrosis in Crohn’s Disease Lesions by Magnetic Resonance Imaging

J. Fletcher, P. Higgins, 2015, The American Journal of Gastroenterology.

Systematic review with network meta‐analysis: the efficacy of anti‐tumour necrosis factor‐alpha agents for the treatment of ulcerative colitis

S. Saini, P. Higgins, S. Vijan, 2014, Alimentary pharmacology & therapeutics.

Development of the Paris Definition of Early Crohn's Disease for Disease-Modification Trials: Results of an International Expert Opinion Process

S. Schreiber, H. Ogata, T. Hibi, 2012, The American Journal of Gastroenterology.

Increased ultraviolet light exposure is associated with reduced risk of inpatient surgery among patients with Crohn's disease.

S. Montain, P. Higgins, A. Waljee, 2015, Journal of Crohn's & colitis.

Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease.

H. Hussain, P. Higgins, S. Swanson, 2011, Radiology.

Developing a Standard Set of Patient-Centred Outcomes for Inflammatory Bowel Disease—an International, Cross-disciplinary Consensus

W. Bemelman, S. Vermeire, R. Fitzpatrick, 2018, Journal of Crohn's & colitis.

Anti-Fibrotic Therapies from Other Organs: What the Gut Can Learn from the Liver, Skin, Lung and Heart

P. Higgins, C. Steiner, 2018 .

Defining an Optimal Adherence Threshold for Patients Taking Subcutaneous Anti-TNFs for Inflammatory Bowel Diseases

S. Saini, P. Higgins, M. Heisler, 2018, The American Journal of Gastroenterology.

Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.

R. Neubig, V. Keshamouni, P. Higgins, 2015, The American journal of pathology.

Corticosteroid Use and Complications in a US Inflammatory Bowel Disease Cohort

S. Saini, Wyndy Wiitala, P. Higgins, 2016, PloS one.

Increased risk of venous thromboembolic events with corticosteroid vs biologic therapy for inflammatory bowel disease.

P. Higgins, M. Skup, J. Chao, 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Primary sclerosing cholangitis: meta-analysis of diagnostic performance of MR cholangiopancreatography.

M. Dave, P. Higgins, B. Elmunzer, 2010, Radiology.

Cost Effectiveness of Ulcerative Colitis Surveillance in the Setting of 5-Aminosalicylates

U. Ladabaum, P. Higgins, J. Rubenstein, 2009, The American Journal of Gastroenterology.

Assessing Clinical Disease Recurrence Using Laboratory Data in Surgically Resected Patients From the TOPPIC Trial.

P. Higgins, Ji Zhu, A. Waljee, 2020, Crohn's & colitis 360.

Continuing Medical Education Improves Gastroenterologists’ Compliance with Inflammatory Bowel Disease Quality Measures

P. Higgins, B. Patel, K. Moreo, 2016, Digestive Diseases and Sciences.

An Observational Cohort Study of Clostridium difficile Ribotype 027 and Recurrent Infection

P. Higgins, V. Young, Krishna Rao, 2018, mSphere.

Elevated fecal calprotectin associates with adverse outcomes from Clostridium difficile infection in older adults

P. Higgins, V. Young, Krishna Rao, 2016, Infectious diseases.

Clostridium difficile ribotype 027: relationship to age, detectability of toxins A or B in stool with rapid testing, severe infection, and mortality.

A. Galecki, D. Aronoff, P. Higgins, 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Adalimumab persistence for inflammatory bowel disease in veteran and insured cohorts.

S. Saini, J. Pugh, Wyndy Wiitala, 2018, The American journal of managed care.

Patient reported symptoms during an ulcerative colitis flare: A Qualitative Focus Group Study

P. Higgins, P. Wren, Joel C. Joyce, 2009, European journal of gastroenterology & hepatology.

How to read a clinical trial paper: a lesson in basic trial statistics.

P. Higgins, S. Govani, 2012, Gastroenterology & hepatology.

Body Fat Composition Assessment Using Analytic Morphomics Predicts Infectious Complications After Bowel Resection in Crohn's Disease

G. Su, P. Higgins, Stewart C. Wang, 2015, Inflammatory bowel diseases.

Characterizing intestinal inflammation and fibrosis in Crohn's disease by photoacoustic imaging: feasibility study.

Xueding Wang, T. Ma, P. Higgins, 2016, Biomedical optics express.

Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting

S. Ng, C. Lees, C. O'Morain, 2020, Gastroenterology.

Editorial: Miles to Go on the SCENIC Route: Should Chromoendoscopy Become the Standard of Care in IBD Surveillance?

P. Higgins, 2015, The American Journal of Gastroenterology.

Serum Glycoproteome Profiles for Distinguishing Intestinal Fibrosis from Inflammation in Crohn's Disease

P. Higgins, D. Lubman, R. Stidham, 2017, PloS one.

Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda

C. Abraham, D. McGovern, P. Higgins, 2013, Inflammatory bowel diseases.

Temporal Gut Microbial Changes Predict Recurrent Clostridium difficile in Patients with and without Ulcerative Colitis

P. Higgins, V. Young, J. Limsrivilai, 2019, bioRxiv.

Colorectal Cancer in Inflammatory Bowel Disease

P. Higgins, R. Stidham, Peter Higgins, 2018, Clinics in Colon and Rectal Surgery.

Iron-deficiency anemia

D. Rockey, P. Higgins, 2003 .

Development and Validation of Machine Learning Models in Prediction of Remission in Patients With Moderate to Severe Crohn Disease

P. Higgins, Ji Zhu, A. Waljee, 2019, JAMA network open.

Risk Stratification of Emergency Room Patients with Crohn’s Disease Could Reduce Computed Tomography Use by Nearly Half

P. Higgins, A. Waljee, S. Govani, 2014 .

Letter: biological drugs for inducing remission in ulcerative colitis – authors' reply

S. Saini, P. Higgins, S. Vijan, 2014, Alimentary pharmacology & therapeutics.

Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis.

David S. Rogers, P. Higgins, Steven K. Huang, 2012, The international journal of biochemistry & cell biology.

Anti-TNF biologic therapies other than infliximab

P. Higgins, J. Adler, C. Steiner, 2017 .

Variations in Health Care Utilization Patterns Among Inflammatory Bowel Disease Patients at Risk for High Medical Service Utilization Enrolled in High Deductible Health Plans.

P. Higgins, J. Kullgren, Megan R. McLeod, 2020, Inflammatory bowel diseases.

Novel Rho/MRTF/SRF Inhibitors Block Matrix-stiffness and TGF-&bgr;–Induced Fibrogenesis in Human Colonic Myofibroblasts

R. Neubig, P. Higgins, L. Johnson, 2014, Inflammatory bowel diseases.

Differentiating Clostridium difficile Colitis from Clostridium difficile Colonization in Ulcerative Colitis: A Role for Procalcitonin?

P. Higgins, J. Limsrivilai, Krishna Rao, 2017, Digestion.

Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials

S. Vermeire, P. Higgins, B. Sands, 2017, Gut.

Investigator-Initiated IBD Trials in the United States: Facts, Obstacles, and Answers

R. Sandler, P. Higgins, B. Sands, 2017, Inflammatory bowel diseases.

Computed tomographic enterography adds information to clinical management in small bowel Crohn's disease

J. Platt, E. Caoili, P. Higgins, 2007, Inflammatory bowel diseases.

Anti-Adhesion Therapies and the Rule of 3 for Rare Events

P. Higgins, A. Waljee, S. Govani, 2013, The American Journal of Gastroenterology.

Epidemiology of Constipation in North America: A Systematic Review

P. Higgins, J. Johanson, 2004, American Journal of Gastroenterology.

Anti-tumour necrosis factor-α therapy and recurrent or new primary cancers in patients with inflammatory bowel disease, rheumatoid arthritis, or psoriasis and previous cancer in Denmark: a nationwide, population-based cohort study.

P. Higgins, K. Allin, A. Waljee, 2019, The lancet. Gastroenterology & hepatology.

Ultrasound Shear Wave Elastography Helps Discriminate Low‐grade From High‐grade Bowel Wall Fibrosis in Ex Vivo Human Intestinal Specimens

J. Rubin, P. Higgins, L. Johnson, 2014, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

High altitude journeys and flights are associated with an increased risk of flares in inflammatory bowel disease patients.

G. Rogler, P. Higgins, A. Schoepfer, 2014, Journal of Crohn's & colitis.

The Association of Medications and Vaccination with Risk of Pneumonia in Inflammatory Bowel Disease.

Wyndy Wiitala, P. Higgins, A. Waljee, 2019, Inflammatory bowel diseases.

De-escalation of IBD Therapy: When, Who, and How?

S. Saini, P. Higgins, A. Waljee, 2019, Crohn's & Colitis 360.

Voting with Their Feet (VWF) Endpoint: A Meta‐Analysis of an Alternative Endpoint in Clinical Trials, Using 5‐ASA Induction Studies in Ulcerative Colitis

P. Higgins, A. Waljee, S. Rangwalla, 2009, Inflammatory bowel diseases.

Ultrasound shear wave elastography in pediatric stricturing small bowel Crohn disease: correlation with histology and second harmonic imaging microscopy

J. Rubin, P. Higgins, L. Johnson, 2022, Pediatric Radiology.

Challenges in the Pathophysiology, Diagnosis and Management of Intestinal Fibrosis in Inflammatory Bowel Disease.

G. Rogler, P. Higgins, G. D'Haens, 2019, Gastroenterology.

Intestinal Dilation and Platelet:Albumin Ratio Are Predictors of Surgery in Stricturing Small Bowel Crohn's Disease.

P. Higgins, A. Waljee, R. Stidham, 2016, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis

A. Morris, P. Higgins, J. Waljee, 2006, Gut.

5-ASA to sulfasalazine drug switch program in patients with ulcerative colitis.

P. Higgins, S. Bernstein, A. Waljee, 2018, The American journal of managed care.

Age Disparities in the Use of Steroid-sparing Therapy for Inflammatory Bowel Disease

S. Saini, Wyndy Wiitala, J. Sussman, 2016, Inflammatory bowel diseases.

Identification of symptom domains in ulcerative colitis that occur frequently during flares and are responsive to changes in disease activity

Sijian Wang, M. Dave, P. Higgins, 2008, Health and quality of life outcomes.

Pushing the pedal to the metal: should we accelerate infliximab therapy for patients with severe ulcerative colitis?

G. Rogler, P. Higgins, H. Herfarth, 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis.

P. Higgins, G. D'Haens, W. Sandborn, 2020, Gastroenterology.

Increased Intestinal Permeability is Associated with Later Development of Crohn's Disease.

A. Paterson, M. Surette, C. Lees, 2020, Gastroenterology.

Strong Response to SARS-CoV-2 Vaccine Additional Doses Among Patients With Inflammatory Bowel Diseases

P. Higgins, A. Bousvaros, M. Bewtra, 2022, Clinical Gastroenterology and Hepatology.

Efficacy and outcome of Tofacitinib in Immune checkpoint inhibitor colitis.

P. Higgins, L. Fecher, W. Sharfman, 2020, Gastroenterology.

Tofacitinib for Biologic-Experienced Hospitalized Patients with Acute Severe Ulcerative Colitis: A Retrospective Case-Control Study.

P. Higgins, L. Johnson, A. Waljee, 2021, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

How early to take arms against a sea of troubles? The case for aggressive early therapy in Crohn's disease to prevent fibrotic intestinal strictures.

P. Higgins, R. Stidham, S. Govani, 2013, Journal of Crohn's & colitis.

Editorial: The IBD Drug Pipeline—Ready to Deliver?

P. Higgins, 2014, The American Journal of Gastroenterology.

New Keys to Maintenance Treatment in Ulcerative Colitis

P. Higgins, 2010, Digestive Diseases.

Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response

J. Gisbert, P. Higgins, A. Hart, 2012, Inflammatory bowel diseases.

Value of mucosal assessment and biomarkers in inflammatory bowel disease

P. Higgins, R. Stidham, 2010, Expert review of gastroenterology & hepatology.

Mapping the adult human esophagus in vivo and in vitro.

Alyssa J Miller, P. Higgins, Jules Lin, 2022, Development.

Response to Feagan et al.

P. Higgins, A. Waljee, S. Govani, 2014, The American Journal of Gastroenterology.

Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn's Disease

P. Higgins, N. Pausawasdi, A. Shreiner, 2017, The American Journal of Gastroenterology.

A Care Coordination Intervention Improves Symptoms but not Charges in High-Risk Patients with Inflammatory Bowel Disease.

A. Fendrick, S. Saini, P. Higgins, 2021, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

The Development of Patient-Reported Outcome Measures in Inflammatory Bowel Disease.

P. Higgins, 2018, Gastroenterology & hepatology.

Safety, Pharmacokinetics, and Efficacy of Olorinab, a Peripherally Acting, Highly Selective, Full Agonist of the Cannabinoid Receptor 2, in a Phase 2a Study of Patients With Chronic Abdominal Pain Associated With Crohn’s Disease

S. Hanauer, P. Higgins, B. Yacyshyn, 2020, Crohn's & colitis 360.

Bringing the Inflamed and Fibrotic Bowel into Focus: Imaging in Inflammatory Bowel Disease

P. Higgins, J. Adler, R. Stidham, 2009 .

The Prognostic Power of the NOD2 Genotype for Complicated Crohn's Disease: A Meta-Analysis

P. Higgins, J. Adler, B. Dwamena, 2011, The American Journal of Gastroenterology.

The Prognostic Power of the NOD 2 Genotype for Complicated Crohn ’ s Disease : A Meta-Analysis

P. Higgins, J. Adler, B. Dwamena, 2011 .

Primary Sclerosing Cholangitis: Meta-Analysis of Diagnostic Performance of MR

M. Dave, P. Higgins, B. Elmunzer, 2010 .

A Primer on Effectiveness and Efficacy Trials

Amit G Singal, Akbar K Waljee, P. Higgins, 2014, Clinical and Translational Gastroenterology.

European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies.

R. Dummer, G. Rogler, P. Higgins, 2015, Journal of Crohn's & colitis.

Statins and cancer prevention

Stephen B. Gruber, S. Gruber, S. Lippman, 2005, Nature Reviews Cancer.

Empiric Quadruple vs. Triple Therapy for Primary Treatment of Helicobacter pylori Infection: Systematic Review and Meta-Analysis of Efficacy and Tolerability

P. Moayyedi, W. Chey, P. Higgins, 2010, The American Journal of Gastroenterology.

Prior Helicobacter pylori infection ameliorates Salmonella typhimurium‐induced colitis: Mucosal crosstalk between stomach and distal intestine

Min Zhang, P. Higgins, L. Johnson, 2011, Inflammatory bowel diseases.

Association between Helicobacter pylori infection and inflammatory bowel disease: A meta‐analysis and systematic review of the literature†

M. Dave, P. Higgins, J. Kao, 2010, Inflammatory bowel diseases.

Efficacy of Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

P. Higgins, A. Waljee, C. Steiner, 2019, The American journal of gastroenterology.

Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease.

J. Rubin, P. Higgins, Kang Kim, 2011, Gastroenterology.

Extra-intestinal malignancies in inflammatory bowel disease: results of the 3rd ECCO Pathogenesis Scientific Workshop (III).

P. Higgins, H. Sokol, Joel C. Joyce, 2014, Journal of Crohn's & colitis.

A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis.

Richard S. Kwon, A. Chak, J. Willis, 2012, The New England journal of medicine.

The risk of post-ERCP pancreatitis and the protective effect of rectal indomethacin in cases of attempted but unsuccessful prophylactic pancreatic stent placement.

A. Chak, P. Higgins, S. Sherman, 2015, Gastrointestinal endoscopy.

Does Rectal Indomethacin Eliminate the Need for Prophylactic Pancreatic Stent Placement in Patients Undergoing High-Risk ERCP? Post hoc Efficacy and Cost-Benefit Analyses Using Prospective Clinical Trial Data

A. Chak, S. Saini, R. Hayward, 2013, The American Journal of Gastroenterology.

Machine Learning in Medicine: A Primer for Physicians

Akbar K Waljee, P. Higgins, A. Waljee, 2010, The American Journal of Gastroenterology.

A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis

P. Higgins, A. Waljee, B. Elmunzer, 2008, Gut.

Charting human development using a multi-endodermal organ atlas and organoid models

I. Glass, P. Higgins, B. Treutlein, 2021, Cell.

Management of Crohn Disease: A Review.

P. Higgins, K. Cushing, 2021, JAMA.

Assessing Small Bowel Stricturing and Morphology in Crohn's Disease Using Semi-automated Image Analysis.

G. Su, P. Higgins, Stewart C. Wang, 2019, Inflammatory bowel diseases.

Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

Ajay S. Gulati, A. Griffiths, R. Baldassano, 2019, The American journal of gastroenterology.

Induction and Maintenance Treatment With Upadacitinib Improves Health-Related Quality of Life in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 Study Results

S. Vermeire, P. Higgins, J. Lindsay, 2023, Inflammatory bowel diseases.

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

P. Higgins, N. Barnich, P. Kuffa, 2019, Mucosal Immunology.

Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.

Miquel Sans, Peter Higgins, G. Rogler, 2012, Journal of Crohn's & colitis.

Tofacitinib Induction Therapy Reduces Symptoms Within 3 Days for Patients With Ulcerative Colitis

S. Hanauer, P. Higgins, C. Nduaka, 2019, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

CD4+ tissue-resident memory T-cells expand and are a major source of mucosal tumor necrosis factor α in active Crohn's Disease.

P. Higgins, W. Zou, J. Kao, 2019, Journal of Crohn's & colitis.

Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, in Patients With Moderate to Severe Crohn's Disease: A Phase 2a Study.

K. Patra, R. Faggioni, P. Higgins, 2017, Gastroenterology.

Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients with Crohn's Disease.

P. Higgins, B. Sands, G. D'Haens, 2021, Gastroenterology.

Results of the 4th scientific workshop of the ECCO (Group II): markers of intestinal fibrosis in inflammatory bowel disease.

P. Higgins, V. Annese, I. Dotan, 2014, Journal of Crohn's & colitis.

Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts

P. Higgins, L. Johnson, D. Tschumperlin, 2013, Inflammatory bowel diseases.

Functional Characterization of Inflammatory Bowel Disease–Associated Gut Dysbiosis in Gnotobiotic Mice

P. Higgins, A. Hirayama, V. Young, 2016, Cellular and molecular gastroenterology and hepatology.

EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) Study Identifies Fecal Calprotectin, Serum MMP9, and Serum IL-22 as a Novel Combination of Biomarkers for Crohn's Disease Activity: Role of Cross-Sectional Imaging

J. Fletcher, P. Higgins, L. Diehl, 2013, The American Journal of Gastroenterology.

Efficacy of Induction Therapy With High‐Intensity Tofacitinib in 4 Patients With Acute Severe Ulcerative Colitis

P. Higgins, A. Waljee, John I. Allen, 2019, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Who Wants to Take a Thiopurine Holiday?

P. Higgins, 2011, American Journal of Gastroenterology.

Modelling dysplasia detection in ulcerative colitis: clinical implications of surveillance intensity

P. Higgins, C. Siegel, D. Awais, 2009, Gut.

In vitro models of the human esophagus reveal ancestrally diverse response to injury

P. Higgins, Jules Lin, M. Dame, 2021, bioRxiv.

X-linked inhibitor of apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis.

P. Higgins, E. White, J. E. King, 2013, American journal of respiratory cell and molecular biology.

Therapeutic High-Density Barium Enema in a Case of Presumed Diverticular Hemorrhage

P. Higgins, N. Pausawasdi, M. Al-Hawary, 2011, Case Reports in Gastroenterology.

Comparison of noncontrast MRI magnetization transfer and T2‐Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model

P. Higgins, L. Johnson, S. Swanson, 2015, Journal of magnetic resonance imaging : JMRI.

Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts.

P. Higgins, E. White, J. E. King, 2012, Advances in bioscience and biotechnology.

Response to Laine et al.

P. Higgins, 2015, The American journal of gastroenterology.

A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture

P. Higgins, J. Colacino, J. Kao, 2018, Cellular and molecular gastroenterology and hepatology.

European Crohn's and Colitis Organisation Topical Review on Prediction, Diagnosis and Management of Fibrostenosing Crohn's Disease.

W. Bemelman, P. Higgins, G. Van Assche, 2016, Journal of Crohn's & colitis.

Temporal Gut Microbial Changes Predict Recurrent Clostridiodes Difficile Infection in Patients With and Without Ulcerative Colitis.

P. Higgins, V. Young, J. Limsrivilai, 2020, Inflammatory bowel diseases.

Management of Crohn Disease-Reply.

P. Higgins, K. Cushing, 2021, JAMA.

Validation of models using basic parameters to differentiate intestinal tuberculosis from Crohn’s disease: A multicenter study from Asia

S. Ng, P. Higgins, N. Pausawasdi, 2020, PloS one.

Characterizing intestinal strictures of Crohn's disease in vivo by endoscopic photoacoustic imaging.

Shengchun Liu, Guan Xu, Xueding Wang, 2019, Biomedical optics express.

Poor Adherence to Subcutaneous Biologics for Inflammatory Bowel Disease Is Associated with a 50% Increase in Hospitalizations and Steroid Use: 652

P. Higgins, M. Heisler, J. Waljee, 2016 .

Combination of thiopurines and allopurinol: adverse events and clinical benefit in IBD.

P. Higgins, S. Govani, 2010, Journal of Crohn's & colitis.

Response to 'The end of the dosage of 6 Thioguanine nucleotides? Not so sure…'.

P. Higgins, Ji Zhu, A. Waljee, 2018, Journal of Crohn's & colitis.

External Validation of a Thiopurine Monitoring Algorithm on the SONIC Clinical Trial Dataset

P. Higgins, Ji Zhu, A. Waljee, 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Machine Learning Algorithms for Objective Remission and Clinical Outcomes with Thiopurines

P. Higgins, Ji Zhu, A. Waljee, 2017, Journal of Crohn's & colitis.

Endoscopic Balloon Dilation Size and Avoidance of Surgery in Stricturing Crohn's Disease

P. Higgins, A. Waljee, R. Stidham, 2017, Inflammatory bowel diseases.

Factors associated with poor outcomes in adults with newly diagnosed ulcerative colitis.

P. Higgins, W. Reinisch, Andrew R. Reinink, 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis.

R. Sandler, P. Higgins, B. Sands, 2018, Gastroenterology.

Dillman et al—Contrast-Enhanced Sonography of Crohn Disease Strictures Can Contrast-Enhanced Sonography Detect Bowel Wall Fibrosis in Mixed Inflammatory and Fibrotic Crohn’s Disease Lesions in an Animal Model?

J. Rubin, P. Higgins, L. Johnson, 2017 .

US elastography-derived shear wave velocity helps distinguish acutely inflamed from fibrotic bowel in a Crohn disease animal model.

J. Rubin, P. Higgins, L. Johnson, 2013, Radiology.

Use of Accelerated Induction Strategy of Infliximab for Ulcerative Colitis in Hospitalized Patients at a Tertiary Care Center

P. Higgins, A. Waljee, K. Hardiman, 2019, Digestive Diseases and Sciences.

Systematic review: impact of non‐adherence to 5‐aminosalicylic acid products on the frequency and cost of ulcerative colitis flares

K. Kaulback, D. Rubin, P. Higgins, 2009, Alimentary pharmacology & therapeutics.

415a – Anti-Tumor Necrosis Factor Therapy is Not Associated with Post-Operative Infection: Results from Prospective Cohort of Ulcerative Colitis and Crohn's Disease Patients Undergoing Surgery to Identify Risk Factors for Postoperative Infection I (Puccini)

P. Higgins, B. Sands, J. Leighton, 2019, Gastroenterology.

Endoscopic Mucosal Healing Predicts Favorable Clinical Outcomes in Inflammatory Bowel Disease: A Meta-analysis

P. Higgins, Andrew R. Reinink, Terrence C Lee, 2016, Inflammatory bowel diseases.

Imaging Features Associated With Failure of Nonoperative Management of Intraabdominal Abscesses in Crohn Disease.

D. Perl, P. Higgins, A. Waljee, 2019, Inflammatory bowel diseases.

Perceived and Actual Quality of Life With Ulcerative Colitis: A Comparison of Medically and Surgically Treated Patients

Aditi Saxena, Akbar K Waljee, A. Morris, 2011, The American Journal of Gastroenterology.

P106 Ultrasound shear wave elastography detects bowel wall fibrosis in ex vivo human Crohn's disease specimens

J. Rubin, P. Higgins, L. Johnson, 2014 .

Treatment Patterns and Standardized Outcome Assessments Among Patients With Inflammatory Conditions of the Pouch in a Prospective Multicenter Registry

M. Dubinsky, P. Higgins, J. Galanko, 2022, Crohn's & colitis 360.

Controversies in mucosal healing in ulcerative colitis.

P. Higgins, A. Kornbluth, S. Kane, 2009, Inflammatory bowel diseases.

Efficacy and Safety of Dual Targeted Therapy for Partially or Non-responsive Inflammatory Bowel Disease: A Systematic Review of the Literature

P. Higgins, A. Waljee, S. Cohen-Mekelburg, 2023, Digestive Diseases and Sciences.

516 Accelerated Dosing of Infliximab Prevents Colectomy Within 90 Days in Only Half of Patients With Severe Ulcerative Colitis

P. Higgins, A. Waljee, K. Hardiman, 2016 .

Cost utility of inflammation-targeted therapy for patients with ulcerative colitis.

S. Saini, P. Higgins, A. Waljee, 2012, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

The Relationship Between Opioid Use and Healthcare Utilization in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

P. Higgins, S. Cohen-Mekelburg, J. Sheehan, 2022, Inflammatory bowel diseases.

Incidence and predictors of new persistent opioid use following inflammatory bowel disease flares treated with oral corticosteroids

P. Higgins, J. Waljee, A. Waljee, 2018, Alimentary pharmacology & therapeutics.

Factors That Predict High Health Care Utilization and Costs for Patients With Inflammatory Bowel Diseases

P. Higgins, A. Waljee, J. Limsrivilai, 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

The effect of mesalazine therapy on quality of life in patients with mildly and moderately active ulcerative colitis

P. Higgins, D. Ramsey, E. Irvine, 2008, Alimentary pharmacology & therapeutics.

Massive lower gastrointestinal bleeding after rejection of pancreatic transplants

P. Higgins, M. DiMagno, J. R. Parker, 2005, Nature Clinical Practice Gastroenterology &Hepatology.

Upadacitinib as induction and maintenance therapy for moderately to severely active ulcerative colitis: results from three phase 3, multicentre, double-blind, randomised trials

S. Vermeire, P. Higgins, G. D'Haens, 2022, The Lancet.

Prospective Cohort Study to Investigate the Safety of Preoperative Tumor Necrosis Factor Inhibitor Exposure in Patients with Inflammatory Bowel Disease Undergoing Intra-abdominal Surgery.

P. Higgins, B. Sands, J. Leighton, 2022, Gastroenterology.

Prevalence and Effect of Intestinal Infections Detected by a PCR-Based Stool Test in Patients with Inflammatory Bowel Disease

P. Higgins, L. Johnson, A. Waljee, 2020, Digestive Diseases and Sciences.

Novel fecal biomarkers that precede clinical diagnosis of ulcerative colitis.

P. Moayyedi, G. Kaplan, M. Silverberg, 2020, Gastroenterology.

OP24 Efficacy and safety of upadacitinib induction therapy in patients with Moderately to Severely Active Ulcerative Colitis: Results from the phase 3 U-ACHIEVE study

S. Vermeire, P. Higgins, S. Danese, 2021, Journal of Crohn's & Colitis.

Individual health discount rate in patients with ulcerative colitis

A. Morris, P. Higgins, J. Waljee, 2011, Inflammatory bowel diseases.

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials.

A. Ananthakrishnan, J. Reguła, D. Rubin, 2021, The lancet. Gastroenterology & hepatology.

OP34 Efficacy and safety of advanced induction and maintenance therapies in patients with moderately to severely active Ulcerative Colitis: An indirect treatment comparison using Bayesian network meta-analysis

P. Higgins, R. Panaccione, S. Danese, 2022, Journal of Crohn's and Colitis.

DOP41 Efficacy and safety of extended induction treatment with upadacitinib 45 mg once daily followed by maintenance upadacitinib 15 or 30 mg once daily in patients with moderately to severely active Ulcerative Colitis

P. Higgins, R. Panaccione, S. Danese, 2022, Journal of Crohn's and Colitis.

Increasing ultraviolet light exposure is associated with reduced mortality from Clostridium difficile infection

P. Higgins, A. Waljee, R. Stidham, 2015, United European gastroenterology journal.

Meta‐analysis: surveillance with ultrasound for early‐stage hepatocellular carcinoma in patients with cirrhosis

J. Marrero, R. Salgia, M. Volk, 2009, Alimentary pharmacology & therapeutics.

Inflammatory Bowel Disease Risk Variants Are Associated with an Increased Risk of Skin Cancer

E. Speliotes, P. Higgins, J. Gudjonsson, 2021, medRxiv.

The IBD Therapeutic Pipeline is Primed to Produce

P. Higgins, C. Steiner, S. Katz, 2019 .

A Predictive Model to Identify Complicated Clostridiodes difficile Infection

P. Higgins, V. Young, C. Steiner, 2022, medRxiv.

Development and validation of the Crohn’s disease patient-reported outcomes signs and symptoms (CD-PRO/SS) diary

N. Leidy, D. Patrick, D. Revicki, 2018, Journal of Patient-Reported Outcomes.

Epidemiology, Diagnosis, and Management of Clostridium difficile Infection in Patients with Inflammatory Bowel Disease

P. Higgins, Krishna Rao, Peter D. R. Higgins, 2016, Inflammatory bowel diseases.

Predicting corticosteroid‐free endoscopic remission with vedolizumab in ulcerative colitis

J. Zhu, P. Higgins, A. Waljee, 2018, Alimentary pharmacology & therapeutics.

Understanding clinician connections to inform efforts to promote high-quality inflammatory bowel disease care

Geoffrey H. Siwo, M. Manojlovich, S. Saini, 2022, PloS one.

The Clinical Accuracy of the BÜHLMANN fCAL ELISA in the Differentiation of Inflammatory Bowel Disease From Irritable Bowel Syndrome: A Multicenter Prospective Case–Control Study

R. Arsenescu, P. Higgins, A. Bousvaros, 2019, Crohn's & Colitis 360.

Intestinal organoids: a model of intestinal fibrosis for evaluating anti-fibrotic drugs.

P. Higgins, L. Johnson, J. Spence, 2015, Experimental and molecular pathology.

Spironolactone and Colitis: Increased Mortality in Rodents and in Humans

P. Higgins, B. Gillespie, L. Johnson, 2012, Inflammatory bowel diseases.

Impact of SARS-CoV-2 Vaccination on Inflammatory Bowel Disease Activity and Development of Vaccine-Related Adverse Events: Results From PREVENT-COVID

M. Dubinsky, P. Higgins, A. Bousvaros, 2021, Inflammatory bowel diseases.

Response to Mansoor et al: ‘epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’

Kira L. Newman, P. Higgins, M. Long, 2022, Gut.

A randomised trial of sheathed versus standard forceps for obtaining uncontaminated biopsy specimens of microbiota from the terminal ileum

M. Dave, P. Higgins, L. Johnson, 2011, Gut.

AXL Is a Potential Target for the Treatment of Intestinal Fibrosis.

P. Higgins, L. Johnson, J. Spence, 2020, Inflammatory bowel diseases.

254 A Multicenter Study to Evaluate Magnetic Resonance Enterography (MRE) for Selection of Crohn's Disease Patients for Inclusion Into a Therapeutic Clinical Trial

P. Rutgeerts, S. Vermeire, C. Santillan, 2014 .

Long‐term safety and tolerability of oral tofacitinib in patients with Crohn’s disease: results from a phase 2, open‐label, 48‐week extension study

P. Higgins, G. D'Haens, G. Chan, 2017, Alimentary pharmacology & therapeutics.

Long‐term safety and tolerability of oral tofacitinib in patients with Crohn’s disease: results from a phase 2, open‐label, 48‐week extension study

P. Higgins, G. D'Haens, G. Chan, 2017, Alimentary Pharmacology and Therapeutics.

Systematic review with network meta‐analysis: the efficacy of anti‐TNF agents for the treatment of Crohn's disease

S. Saini, P. Higgins, S. Vijan, 2014, Alimentary pharmacology & therapeutics.

P. Higgins, C. Steiner, J. Berinstein, 2021, Clinical Gastroenterology and Hepatology.

The quantitative validation of non‐endoscopic disease activity indices in ulcerative colitis

M. Schwartz, P. Higgins, J. Mapili, 2006, Alimentary pharmacology & therapeutics.

Trends of 5-Aminosalicylate Medication Use in Patients With Crohn Disease.

P. Higgins, A. Waljee, M. Noureldin, 2020, Inflammatory bowel diseases.

Association of Continuity of Care With Outcomes in US Veterans With Inflammatory Bowel Disease

S. Saini, Wyndy Wiitala, P. Higgins, 2020, JAMA network open.

An evidence-based approach to inflammatory bowel disease

P. Higgins, E. Zimmermann, 2004 .

Should we be CHARMed?

P. Higgins, D. Awais, 2007, Inflammatory bowel diseases.

Predicting Hospitalization and Outpatient Corticosteroid Use in Inflammatory Bowel Disease Patients Using Machine Learning.

Akbar K Waljee, Wyndy L Wiitala, Wyndy Wiitala, 2017, Inflammatory bowel diseases.

Factors Affecting Initial Humoral Immune Response to SARS-CoV-2 Vaccines Among Patients With Inflammatory Bowel Diseases

M. Dubinsky, P. Higgins, A. Bousvaros, 2021, The American journal of gastroenterology.

AJG-21-2636 462..469

M. Dubinsky, P. Higgins, A. Bousvaros, 2022 .

Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic

A. Fendrick, P. Higgins, A. Waljee, 2022, Research in Social and Administrative Pharmacy.

Validation of a tool predicting important findings on computed tomography among Crohn’s disease patients

P. Higgins, M. Saul, K. Kocher, 2017, United European gastroenterology journal.

Risk stratification of emergency department patients with Crohn's disease could reduce computed tomography use by nearly half.

P. Higgins, A. Waljee, S. Govani, 2014, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

The Risk of SARS-CoV-2 in Immunosuppressed IBD Patients

S. Ng, P. Higgins, S. Danese, 2020, Crohn's & colitis 360.

Erratum: EMerging BiomARKers in inflammatory bowel disease (EMBARK) study identifies fecal calprotectin, serum MMP9, and serum IL-22 as a novel combination of biomarkers for crohn's disease activity: Role of cross-sectional imaging (American Journal of Gastroenterology (2013) 108 (1891-1900) DOI: 10

J. Fletcher, P. Higgins, L. Diehl, 2014 .

Acquisition of NOTCH dependence is a hallmark of human intestinal stem cell maturation

I. Glass, P. Higgins, J. Spence, 2022, Stem cell reports.

Su1220 Rectal Bleeding Accurately Reflects Level of Mucosal Inflammation in Patients With Ulcerative Colitis

Christopher R. Cabanski, J. Mansfield, P. Rutgeerts, 2015 .

Drug Insight: statins and gastrointestinal cancer

P. Higgins, T. Bhuket, 2006, Nature Clinical Practice Gastroenterology &Hepatology.

Atorvastatin Induces Apoptosis In Vitro and Slows Growth of Tumor Xenografts but Not Polyp Formation in Min Mice

P. Higgins, L. Johnson, K. Eaton, 2010, Digestive Diseases and Sciences.

Strain-photoacoustic imaging as a potential tool for characterizing intestinal fibrosis.

Xueding Wang, J. Rubin, P. Higgins, 2019, Gastroenterology.

Identifying intestinal fibrosis and inflammation by spectroscopic photoacoustic imaging: an animal study in vivo.

Jie Yuan, Guan Xu, Xueding Wang, 2018, Biomedical optics express.

Imaging of intestinal fibrosis: current challenges and future methods

P. Higgins, R. Stidham, 2016, United European gastroenterology journal.

Point-counterpoint: Are we overtreating patients with mild ulcerative colitis?

S. Saini, P. Higgins, S. Vijan, 2014, Journal of Crohn's & colitis.

Using bibliometrics to advance your academic career.

P. Higgins, R. Stidham, Kay Sauder, 2012, Gastroenterology.

Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

P. Higgins, R. Jenq, N. Karlsson, 2020, Nature Medicine.

Transient or persistent norovirus infection does not alter the pathology of Salmonella typhimurium induced intestinal inflammation and fibrosis in mice.

P. Higgins, L. Johnson, D. Moons, 2011, Comparative immunology, microbiology and infectious diseases.

Ultrasound Elasticity Imaging Can Distinguish Intestinal Inflammation From Fibrosis in the Rat TNBS Colitis Model

J. Rubin, P. Higgins, Kang Kim, 2011 .

A Primer on Predictive Models

Amit G Singal, Akbar K Waljee, P. Higgins, 2014, Clinical and Translational Gastroenterology.

Predicting Corticosteroid-Free Biologic Remission with Vedolizumab in Crohn's Disease.

Akbar K Waljee, P. Higgins, Ji Zhu, 2018, Inflammatory bowel diseases.

Improvement of predictive models of risk of disease progression in chronic hepatitis C by incorporating longitudinal data

P. Higgins, Ji Zhu, A. Waljee, 2015, Hepatology.

Biomarkers for the Prediction and Diagnosis of Fibrostenosing Crohn's disease: A Systematic Review.

J. Fletcher, P. Higgins, M. Baker, 2021, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

P023 CROHN’S DISEASE AND ULCERATIVE COLITIS PATIENT PERSPECTIVES ON PARTICIPATION IN IBD CLINICAL TRIALS

P. Higgins, A. Anderson, C. Heller, 2018 .

Profiles of Web-based Portal Users with Inflammatory Bowel Disease.

Kira L. Newman, J. Piette, P. Higgins, 2023, Inflammatory bowel diseases.

Optimisation of Intestinal Fibrosis and Survival in the Mouse S. Typhimurium Model for Anti-fibrotic Drug Discovery and Preclinical Applications

R. Neubig, P. Higgins, L. Johnson, 2016, Journal of Crohn's & colitis.

Coronavirus Disease 2019 (COVID-19) Clinical Trial Oversight at a Major Academic Medical Center: Approach of Michigan Medicine

R. Hyzy, A. Lok, P. Higgins, 2020, Clinical Infectious Diseases.

COVID-19 Clinical Trial Oversight at a Major Academic Medical Center: Approach of the Michigan Medicine COVID-19 Clinical Trial Committees

A. Lok, P. Higgins, Kayte Spector-Bagdady, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Low Rates of Breakthrough COVID-19 Infection After SARS-CoV-2 Vaccination in Patients With Inflammatory Bowel Disease

M. Dubinsky, P. Higgins, A. Bousvaros, 2022, Inflammatory bowel diseases.

Endoscopic and Histological Assessment, Correlation, and Relapse in Clinically Quiescent Ulcerative Colitis (MARQUEE).

P. Higgins, J. Galanko, H. Herfarth, 2020, Inflammatory bowel diseases.

Different definitions of remission for ulcerative colitis result in large variations of clinical outcome scores: P-0057

P. Higgins, R. Eusebio, S. Kane, 2007 .

Citrobacter rodentium Induces Tissue-Resident Memory CD4+ T Cells

P. Higgins, W. Zou, J. Kao, 2019, Infection and Immunity.

Measurement of Fibrosis in Crohn's Disease Strictures with Imaging and Blood Biomarkers to Inform Clinical Decisions

P. Higgins, 2017, Digestive Diseases.

Systemic Inflammatory Responses in Ulcerative Colitis Patients and Clostridium difficile Infection

P. Higgins, L. Johnson, A. Waljee, 2018, Digestive Diseases and Sciences.

Ultrasound Elastography of the Bowel

J. Rubin, P. Higgins, L. Johnson, 2019, Cross-Sectional Imaging in Crohn’s Disease.

CT utilization abruptly increases at age 18 among patients with inflammatory bowel diseases in the hospital

P. Higgins, J. Rubenstein, A. Waljee, 2018, PloS one.

Statins reduce inflammation, DVT, osteoporosis, and colon cancer: Could they be of benefit in IBD?

P. Higgins, A. Waljee, 2006 .

P435 Rapidity of symptomatic and inflammatory biomarker improvements following upadacitinib induction treatment: data from the U-ACHIEVE study

S. Vermeire, P. Higgins, G. D'Haens, 2019, Journal of Crohn's and Colitis.

P390 Methotrexate is not superior to placebo in maintaining remission in patients with ulcerative colitis: results from the MERIT-UC study

P. Higgins, B. Sands, J. Lewis, 2018 .

The IBD SGI Diagnostic Test Is Frequently Used by Non-gastroenterologists to Screen for Inflammatory Bowel Disease.

P. Higgins, A. Waljee, R. Stidham, 2018, Inflammatory Bowel Diseases.

Reply to Body Fat Composition Predicts Infectious Complications After Bowel Resection in Crohn's Disease.

G. Su, P. Higgins, Stewart C. Wang, 2015, Inflammatory bowel diseases.

Development and validation of the Ulcerative Colitis patient-reported outcomes signs and symptoms (UC-pro/SS) diary

N. Leidy, D. Patrick, D. Revicki, 2018, Journal of Patient-Reported Outcomes.

CARD-024, a vitamin D analog, attenuates the pro-fibrotic response to substrate stiffness in colonic myofibroblasts.

P. Higgins, L. Johnson, K. Sauder, 2012, Experimental and molecular pathology.

Why Westerners Are Dissatisfied: A Cross-Sectional Study Identifying State-Level Factors Associated with Variation in Private Health Insurance Satisfaction

P. Higgins, Megan R. McLeod, K. Cushing, 2019 .

Letter: comparative efficacy of biological therapy in patients with ulcerative colitis – authors’ reply

S. Saini, P. Higgins, S. Vijan, 2014, Alimentary pharmacology & therapeutics.

Self-Efficacy and the Impact of Inflammatory Bowel Disease on Patients' Daily Lives

J. Piette, S. Saini, P. Higgins, 2023, Clinical and translational gastroenterology.

In-hospital management of inflammatory bowel disease

P. Higgins, J. Berinstein, D. Aintabi, 2023, Current opinion in gastroenterology.

Association of Household Pets, Common Dietary Factors, and Lifestyle Factors with Clostridium difficile Infection

P. Higgins, C. Steiner, Krishna Rao, 2020, Digestive Diseases and Sciences.

Effect of ABT-263 on Intestinal Fibrosis in Human Myofibroblasts, Human Intestinal Organoids, and the Mouse Salmonella typhimurium Model.

P. Higgins, L. Johnson, J. Spence, 2021, Inflammatory bowel diseases.

Vedolizumab more likely to be discontinued than ustekinumab in anti-TNF-experienced patients with fistulizing Crohn’s disease

Kira L. Newman, P. Higgins, L. Johnson, 2023, Therapeutic advances in gastroenterology.

Efficacy of Ustekinumab in Crohn's Disease With and Without Concurrent Autoimmune Skin Disease.

P. Higgins, K. Cushing, J. Sheehan, 2021, Inflammatory bowel diseases.

Tu1794 – Adherent-Invasive Escherichia Coli Colonization Promotes Intestinal Fibrosis Via Activation of Il-33/St2 Signaling

P. Higgins, N. Barnich, P. Kuffa, 2019, Gastroenterology.

Ultrasound shear wave elastography in pediatric stricturing small bowel Crohn disease: correlation with histology and second harmonic imaging microscopy

J. Rubin, P. Higgins, L. Johnson, 2022, Pediatric Radiology.

Assessing risk of fibrosis progression and liver-related clinical outcomes among patients with both early stage and advanced chronic hepatitis C

Ulysses Balis, Akbar K Waljee, P. Higgins, 2017, PloS one.

Jumbo forceps are superior to standard large-capacity forceps in obtaining diagnostically adequate inflammatory bowel disease surveillance biopsy specimens.

P. Higgins, S. Korsnes, J. Greenson, 2008, Gastrointestinal endoscopy.

Characteristics of Facilities With Early and Rapid Ustekinumab Adoption for Patients With Inflammatory Bowel Disease

S. Saini, P. Higgins, Tony Van, 2023, The American journal of gastroenterology.

Epidemiology, Diagnosis, andManagement ofClostridium difficile Infection in Patients with Inflammatory Bowel Disease

P. Higgins, Krishna Rao, 2022 .

Review article: defining remission in ulcerative colitis

C. O'Morain, A. Bitton, M. Kamm, 2011, Alimentary pharmacology & therapeutics.

Efficacy and Safety of Advanced Therapies for Moderately to Severely Active Ulcerative Colitis at Induction and Maintenance: An Indirect Treatment Comparison Using Bayesian Network Meta-analysis

S. Vermeire, P. Higgins, R. Panaccione, 2023, Crohn's & colitis 360.

Proximity to Disease and Perception of Utility: Physicians' vs Patients' Assessment of Treatment Options for Ulcerative Colitis

A. Morris, P. Higgins, J. Waljee, 2011, Diseases of the colon and rectum.

Strong Response to SARS-CoV-2 Vaccine Additional Doses Among Patients With Inflammatory Bowel Diseases

P. Higgins, A. Bousvaros, M. Bewtra, 2022, Clinical Gastroenterology and Hepatology.

Patient reported symptoms during an ulcerative colitis flare: A Qualitative Focus Group Study

P. Higgins, P. Wren, Joel C. Joyce, 2009, European Journal of Gastroenterology and Hepathology.

Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts

P. Higgins, L. Johnson, D. Tschumperlin, 2013, Inflammatory bowel diseases.

Humoral Immune Response and Safety of SARS-CoV-2 Vaccination in Pediatric Inflammatory Bowel Disease

M. Dubinsky, P. Higgins, A. Bousvaros, 2022, The American journal of gastroenterology.

Modelling dysplasia detection in ulcerative colitis: clinical implications of surveillance intensity

P. Higgins, C. Siegel, D. Awais, 2009, Gut.

Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease.

J. Rubin, P. Higgins, Kang Kim, 2011, Gastroenterology.

Elevated fecal calprotectin associates with adverse outcomes from Clostridium difficile infection in older adults

P. Higgins, V. Young, Krishna Rao, 2016, Infectious diseases.

Magnetic resonance enterography is feasible and reliable in multicenter clinical trials in patients with Crohn's disease, and may help select subjects with active inflammation

S. Vermeire, C. Santillan, K. Herrmann, 2016, Alimentary pharmacology & therapeutics.

Value of mucosal assessment and biomarkers in inflammatory bowel disease

P. Higgins, R. Stidham, 2010, Expert review of gastroenterology & hepatology.

Computed tomographic enterography adds information to clinical management in small bowel Crohn's disease

J. Platt, E. Caoili, P. Higgins, 2007, Inflammatory bowel diseases.

Characterizing intestinal strictures with acoustic resolution photoacoustic microscopy

Jun Ni, Shengchun Liu, Xueding Wang, 2016, SPIE BiOS.

Detecting inflammation and fibrosis in bowel wall with photoacoustic imaging in a Crohn's disease animal model

Xueding Wang, Guan Xu, Jack Hu, 2015, Photonics West - Biomedical Optics.

How early to take arms against a sea of troubles? The case for aggressive early therapy in Crohn's disease to prevent fibrotic intestinal strictures.

P. Higgins, R. Stidham, S. Govani, 2013, Journal of Crohn's & colitis.

US elastography-derived shear wave velocity helps distinguish acutely inflamed from fibrotic bowel in a Crohn disease animal model.

J. Rubin, P. Higgins, L. Johnson, 2013, Radiology.

Measurement of Fibrosis in Crohn's Disease Strictures with Imaging and Blood Biomarkers to Inform Clinical Decisions

P. Higgins, 2017, Digestive Diseases.

OP031 Long-term safety and tolerability of oral tofacitinib in patients with Crohn's disease: results from a phase 2 open-label 48-week extension study.

P. Higgins, G. D'Haens, G. Chan, 2017, Journal of Crohn's & colitis.