D. Speiser

发表

Breast cancer and melanoma cell line identification by FTIR imaging after formalin-fixation and paraffin-embedding.

C. Sotiriou, C. Desmedt, D. Larsimont, 2013, The Analyst.

Clonotype Selection and Composition of Human CD8 T Cells Specific for Persistent Herpes Viruses Varies with Differentiation but Is Stable Over Time1

D. Speiser, Emanuela M. Iancu, P. Corthésy, 2009, The Journal of Immunology.

BAFF 60-mer, and Differential BAFF 60-mer Dissociating Activities in Human Serum, Cord Blood and Cerebrospinal Fluid

E. Meinl, D. Speiser, M. Eslami, 2020, Frontiers in Cell and Developmental Biology.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

J. Paul Robinson, Jonathan A. Rebhahn, Kylie M. Quinn, 2019, European journal of immunology.

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

D. Hanahan, R. Zinkernagel, D. Speiser, 1997, The Journal of experimental medicine.

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

C. V. Jongeneel, Brian J. Stevenson, A. Valsesia, 2011, Nature Genetics.

Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing.

Nicolò Riggi, G. Ciriello, C. Rivolta, 2016, American journal of human genetics.

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

D. Speiser, P. Baumgaertner, D. Gfeller, 2017, bioRxiv.

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

D. Speiser, P. Baumgaertner, D. Gfeller, 2017, bioRxiv.

Hit parade for adoptive cell transfer therapy: the best T cells for superior clinical responses.

D. Speiser, 2013, Cancer discovery.

Proteasome-Assisted Identification of a SSX-2-Derived Epitope Recognized by Tumor-Reactive CTL Infiltrating Metastatic Melanoma1

Danila Valmori, Hans-Georg Rammensee, Pedro Romero, 2002, The Journal of Immunology.

of different hematologic lineages before and after relapse leukemia transplanted with T-cell-depleted bone marrow : involvement Characterization of mixed chimerism in patients with chronic myeloid

D. Speiser, B. Chapuis, E. Roosnek, 2003 .

Characterization of mixed chimerism in patients with chronic myeloid leukemia transplanted with T-cell-depleted bone marrow: involvement of different hematologic lineages before and after relapse.

D. Speiser, B. Chapuis, M. Jeannet, 1993, Blood.

Classification of current anticancer immunotherapies

Axel Hoos, Patrizia Agostinis, Fernando Aranda, 2014, Oncotarget.

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients.

Pedro Romero, Nathalie Rufer, Bart Deplancke, 2011, The Journal of clinical investigation.

Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells

Daniel E. Speiser, Dietmar Zehn, Hanspeter Pircher, 2013, Front. Immunol..

Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

D. Speiser, D. Zehn, Hélène Cannelle, 2018, bioRxiv.

Good News from Immunotherapy: Our Immune Defense Stands Up to Cancer

D. Speiser, Silvia A. Fuertes Marraco, N. Neubert, 2017, Front. Young Minds..

Naturally Acquired MAGE-A10- and SSX-2-Specific CD8+ T Cell Responses in Patients with Hepatocellular Carcinoma1

D. Speiser, P. Romero, H. Macdonald, 2005, The Journal of Immunology.

Oligotyping of HLA-A2, -A3, and -B44 subtypes. Detection of subtype incompatibilities between patients and their serologically matched unrelated bone marrow donors.

D. Speiser, N. Rufer, J. Tiercy, 1994, Human immunology.

Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells.

D. Speiser, P. Romero, M. Pittet, 2003, Journal of Immunology.

Lack of tumor recognition by hTERT peptide 540–548‐specific CD8+ T cells from melanoma patients reveals inefficient antigen processing

D. Speiser, P. Romero, D. Valmori, 2001, European journal of immunology.

Human melanoma-specific CD8+ T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2012, Oncoimmunology.

Melan-A/MART-1-Specific CD4 T Cells in Melanoma Patients: Identification of New Epitopes and Ex Vivo Visualization of Specific T Cells by MHC Class II Tetramers1

D. Speiser, P. Romero, K. Thielemans, 2006, The Journal of Immunology.

Specific T Cells by MHC Class II Tetramers Epitopes and Ex Vivo Visualization of Melanoma Patients: Identification of New Melan-A/MART-1-Specific CD4 T Cells in

D. Speiser, P. Romero, K. Thielemans, 2006 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

Microangiopathy in mild chronic venous incompetence (CVI): morphological alterations and increased transcapillary diffusion detected by fluorescence videomicroscopy.

D. Speiser, A. Bollinger, 1991, International journal of microcirculation, clinical and experimental.

Inhibitory Receptors Beyond T Cell Exhaustion

Daniel E. Speiser, D. Speiser, G. Verdeil, 2015, Front. Immunol..

Immunoregulation of Dendritic Cell Subsets by Inhibitory Receptors in Urothelial Cancer.

B. Lhermitte, D. Speiser, L. de Leval, 2017, European urology.

The CD4-like molecule LAG-3, biology and therapeutic applications

D. Speiser, P. Romero, S. Sierro, 2011, Expert opinion on therapeutic targets.

A stepwise protocol to coat aAPC beads prevents out-competition of anti-CD3 mAb and consequent experimental artefacts.

A. Legat, D. Speiser, P. Baumgaertner, 2012, Journal of immunological methods.

Long-lasting stem cell–like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination

M. Delorenzi, D. Speiser, C. Soneson, 2015, Science Translational Medicine.

Assessing ageing of individual T lymphocytes: Mission impossible?

D. Speiser, Emanuela M. Iancu, N. Rufer, 2008, Mechanisms of Ageing and Development.

Recent advances in tumour antigen‐specific therapy: In vivo veritas

D. Speiser, P. Romero, J. Cerottini, 2005, International journal of cancer.

Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens.

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2006, Cancer research.

Identification of melanoma cells and lymphocyte subpopulations in lymph node metastases by FTIR imaging histopathology.

E. Goormaghtigh, N. Wald, D. Speiser, 2016, Biochimica et biophysica acta.

Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients

G. Coukos, D. Speiser, P. Romero, 2020, Journal for immunotherapy of cancer.

Immune monitoring in cancer immunotherapy.

D. Speiser, P. Romero, V. Cerundolo, 2000, Ernst Schering Research Foundation workshop.

Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.

D. Speiser, P. Romero, V. Cerundolo, 1999, Cancer research.

Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.

D. Speiser, P. Romero, D. Valmori, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Ex Vivo IFN-γ Secretion by Circulating CD8 T Lymphocytes: Implications of a Novel Approach for T Cell Monitoring in Infectious and Malignant Diseases1

D. Speiser, P. Romero, M. Pittet, 2001, The Journal of Immunology.

Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich's "magic (nano)bullet" for cancer theranostics?

E. Neufeld, N. Kuster, N. Kuster, 2016, Cancer treatment reviews.

Antigenicity and immunogenicity of Melan‐A/MART‐1 derived peptides as targets for tumor reactive CTL in human melanoma

D. Speiser, P. Romero, N. Rufer, 2002, Immunological reviews.

Defining ‘T cell exhaustion’

E. Wherry, T. Schumacher, W. Haining, 2019, Nature Reviews Immunology.

Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells

G. Coukos, D. Speiser, P. Romero, 2019, Journal of Immunotherapy for Cancer.

Impact of 3 Different Short-term Chemotherapy Regimens on Lymphocyte-depletion and Reconstitution in Melanoma Patients

V. Appay, D. Speiser, V. Voelter, 2010, Journal of immunotherapy.

Low Avidity T Cells Do Not Hinder High Avidity T Cell Responses Against Melanoma

D. Speiser, P. Baumgaertner, D. Vanhecke, 2019, Front. Immunol..

P026. CpG based nano-particle vaccination of melanoma patients induced strong CD8 memory T-cell responses when adjuvanted with imiquimod

R. Dummer, K. Schwarz, D. Speiser, 2011 .

Lack of BRAF mutations in uveal melanoma.

D. Speiser, L. Zografos, S. Salvi, 2003, Cancer research.

Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients

D. Speiser, P. Baumgaertner, P. Romero, 2016, Front. Immunol..

Vaccination‐induced functional competence of circulating human tumor‐specific CD8 T‐cells

D. Speiser, P. Baumgaertner, N. Rufer, 2012, International journal of cancer.

Single MHC-Peptide Complex Allo-MHC-Restricted T Cells Specific for a Ex Vivo Characterization of

D. Speiser, P. Romero, M. Pittet, 2006 .

Immune cell infiltration in colonic cancer: correlation between biopsy and surgical specimens.

N. Demartines, C. Sempoux, P. Yan, 2021, British Journal of Surgery.

Sensitive identification of neoantigens and cognate TCRs in human solid tumors

Brian J. Stevenson, G. Coukos, D. Speiser, 2021, Nature Biotechnology.

Development of a T Cell Receptor Targeting an HLA-A*0201 Restricted Epitope from the Cancer-Testis Antigen SSX2 for Adoptive Immunotherapy of Cancer

S. Rosenberg, D. Speiser, R. Morgan, 2014, PloS one.

Progress and controversies in developing cancer vaccines

D. Speiser, C. Slingluff, 2005, Journal of Translational Medicine.

Optimum in vitro expansion of human antigen‐specific CD8+ T cells for adoptive transfer therapy

V. Appay, D. Speiser, P. Romero, 2005, Clinical and experimental immunology.

Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence

D. Speiser, P. Baumgaertner, N. Rufer, 2015, The Journal of Immunology.

MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial

D. Speiser, V. Voelter, P. Romero, 2014, Journal of Translational Medicine.

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8+ T-cell responses in melanoma patients

R. Dummer, K. Schwarz, D. Speiser, 2012, European journal of immunology.

Biomodulina T partially restores immunosenescent CD4 and CD8 T cell compartments in the elderly

D. Speiser, P. Lorenzo-Luaces, A. Lage, 2019, Experimental Gerontology.

Rapid and Continued T-Cell Differentiation into Long-term Effector and Memory Stem Cells in Vaccinated Melanoma Patients

D. Speiser, Emanuela M. Iancu, P. Baumgaertner, 2016, Clinical Cancer Research.

Selective accumulation of differentiated FOXP3+ CD4+ T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood

D. Speiser, P. Romero, C. Jandus, 2008, Cancer Immunology, Immunotherapy.

Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma

Katie M. Campbell, A. Ribas, R. Damoiseaux, 2020, Science Translational Medicine.

Novel soluble HLA‐A2/MELAN‐A complexes selectively stain a differentiation defective subpopulation of CD8+ T cells in patients with melanoma

D. Speiser, P. Baumgaertner, N. Rufer, 2010, International journal of cancer.

More T Cells versus Better T Cells in Patients with Breast Cancer.

D. Speiser, G. Verdeil, Grégory Verdeil, 2017, Cancer discovery.

Tinkering with nature: the tale of optimizing peptide based cancer vaccines.

D. Speiser, P. Romero, O. Michielin, 2005, Cancer treatment and research.

CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences.

D. Speiser, P. Romero, D. Valmori, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen.

R. Zinkernagel, D. Speiser, O. Haller, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Clinical Implications of CD8+ T-cell infiltration in frequent and rare cancers.

D. Speiser, O. Gaide, L. Feldmeyer, 2013, The Journal of investigative dermatology.

Extrathymic positive selection of αβ T-cell precursors in nude mice

R. Zinkernagel, D. Speiser, Ursula Stiibi, 1992, Nature.

Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma

Esther Danenberg, M. Swartz, N. Wald, 2018, Oncoimmunology.

Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer

L. French, D. Speiser, W. Jochum, 2016, Oncoimmunology.

The Immunobiology of Malignant Melanoma

D. Speiser, S. Ferrone, 2002 .

TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.

T. Mak, D. Speiser, L. Nguyen, 1999, Immunity.

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

D. Speiser, P. Romero, N. Rufer, 2017, JCI insight.

Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells.

D. Speiser, P. Baumgaertner, N. Rufer, 2015, Cancer research.

Immune Cell Migration in Cancer and Immunotherapy

D. Speiser, T. Murray, 2018 .

Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo

T. Mak, D. Speiser, M. Bachmann, 1996, European journal of immunology.

Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen

D. Speiser, P. Baumgaertner, Estelle Devêvre, 2008, Proceedings of the National Academy of Sciences.

Lymphocytes T + Human Effector-Memory CD 8 Four Functionally Distinct Populations of Rufer

D. Speiser, P. Corthésy, Estelle Devêvre, 2007 .

Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients

D. Speiser, P. Romero, N. Rufer, 2013, PloS one.

Tumor-reactive, SSX-2-specific CD8+ T cells are selectively expanded during immune responses to antigen-expressing tumors in melanoma patients.

D. Speiser, P. Romero, D. Valmori, 2003, Cancer research.

Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus

R. Zinkernagel, D. Speiser, H. Macdonald, 1989, The Journal of experimental medicine.

Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships

D. Speiser, P. Baumgaertner, P. Romero, 2013, PloS one.

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny

H. Pircher, R. Zinkernagel, D. Speiser, 1992, The Journal of experimental medicine.

Neonatal tolerance to MIs-1a determinants: deletion or anergy of V beta 6+ T lymphocytes depending upon MHC compatibility of neonatally injected cells.

R. Zinkernagel, D. Speiser, H. Macdonald, 1991, International immunology.

Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus

R. Zinkernagel, D. Speiser, H. Macdonald, 1990, The Journal of experimental medicine.

Acute graft-versus-host disease without costimulation via CD28.

T. Mak, D. Speiser, M. Bachmann, 1997, Transplantation.

Immunological techniques: ex vivo characterization of T cell-mediated immune responses in cancer.

D. Speiser, D. E. Speiser, 2005, Current opinion in immunology.

In vivo activation of melanoma‐specific CD8+ T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus‐specific T cells

D. Speiser, P. Romero, M. Pittet, 2002, European journal of immunology.

A structural model of the immune checkpoint CD160–HVEM complex derived from HDX-mass spectrometry and molecular modeling

Adam K. Sieradzan, Agnieszka S. Karczynska, D. Speiser, 2019, Oncotarget.

CD8 T cell function and cross-reactivity explored by stepwise increased peptide-HLA versus TCR affinity

D. Speiser, P. Baumgaertner, N. Rufer, 2022, Frontiers in Immunology.

Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

D. Speiser, L. Nguyen, P. Ohashi, 2002, The Journal of experimental medicine.

Activation of cytotoxic T cells by solid tumours?

D. Speiser, P. Ohashi, Pamela S. Ohashi, 1998, Cellular and Molecular Life Sciences CMLS.

High-resolution histocompatibility testing of a group of sixteen B44-positive, ABDR serologically matched unrelated donor-recipient pairs. Analysis of serologically undisclosed incompatibilities by cellular techniques, isoelectrofocusing, and HLA oligotyping.

D. Speiser, N. Rufer, R. Kressig, 1993, Human immunology.

Replacement of HLA class II serology by the HLA‐DR microtitre plate oligotyping assay: a one‐year experience in unrelated bone marrow donor selection

B. Mach, D. Speiser, J. Tiercy, 1993, British journal of haematology.

CpG Are Efficient Adjuvants for Specific CTL Induction Against Tumor Antigen-Derived Peptide

D. Speiser, P. Romero, I. Miconnet, 2002, The Journal of Immunology.

Antigen-Derived Peptide CTL Induction Against Tumor CpG Are Efficient Adjuvants for Specific

D. Speiser, P. Romero, I. Miconnet, 2002 .

Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

D. Speiser, R. Maier, B. Ludewig, 2010, mBio.

High-throughput monitoring of human tumor-specific T-cell responses with large peptide pools

G. Coukos, D. Speiser, P. Romero, 2015, Oncoimmunology.

Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses.

D. Speiser, P. Baumgaertner, P. Romero, 2010, Methods in molecular biology.

Dextramers: new generation of fluorescent MHC class I/peptide multimers for visualization of antigen-specific CD8+ T cells.

D. Speiser, P. Romero, D. Peterson, 2006, Journal of immunological methods.

Immuno-monitoring of CD8+ T cells in whole blood versus PBMC samples.

V. Appay, D. Speiser, V. Voelter, 2006, Journal of immunological methods.

CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro.

V. Hornung, G. Hartmann, D. Speiser, 2004, Blood.

Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.

D. Speiser, P. Romero, M. Pittet, 2004, Cancer immunity.

Communicated by : LJ Old Ex vivo detectable activation of MelanA-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA

D. Speiser, P. Romero, M. Pittet, 2004 .

Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.

D. Speiser, P. Romero, M. Pittet, 2003, Seminars in cancer biology.

CpG-A Oligonucleotides Induce a Monocyte-Derived Dendritic Cell-Like Phenotype That Preferentially Activates CD8 T Cells1

T. Giese, G. Hartmann, D. Speiser, 2003, The Journal of Immunology.

Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.

D. Speiser, P. Romero, M. Pittet, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Disease-driven T cell activation predicts immune responses to vaccination against melanoma.

D. Speiser, P. Romero, P. Batard, 2003, Cancer immunity.

T Cells Phenotype That Preferentially Activates CD8 Monocyte-Derived Dendritic Cell-Like CpG-A Oligonucleotides Induce a

T. Giese, G. Hartmann, D. Speiser, 2003 .

Functional Avidity of Tumor Antigen-Specific CTL Recognition Directly Correlates with the Stability of MHC/Peptide Multimer Binding to TCR1

D. Speiser, P. Romero, D. Valmori, 2002, The Journal of Immunology.

This information is current as to TCR Stability of MHC / Peptide Multimer Binding theCTL Recognition Directly Correlates with Functional Avidity of Tumor Antigen-Specific Romero and Danila

D. Speiser, P. Romero, D. Valmori, 2002 .

Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.

D. Speiser, P. Romero, D. Valmori, 2001, Cancer research.

Antitumor Activity Avidity-specific Cytolytic T Lymphocytes Show Superior : High 262 − 254 Heterogeneous T-Cell Response to MAGE-A 10 Updated Version

D. Speiser, P. Romero, D. Valmori, 2001 .

Efficient Simultaneous Presentation of NY-ESO-1/LAGE-1 Primary and Nonprimary Open Reading Frame-Derived CTL Epitopes in Melanoma

D. Speiser, P. Romero, D. Valmori, 2000, The Journal of Immunology.

Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.

D. Speiser, U. Şahin, P. Romero, 2000, Cancer research.

T Cells in Melanoma + Melan-A-Specific CD8 Usage Reveals a Large Repertoire of -Chain b Tetramer-Guided Analysis of TCR

D. Speiser, P. Romero, D. Valmori, 2000 .

CTL Epitopes in Melanoma Nonprimary Open Reading Frame-Derived NY-ESO-1 / LAGE-1 Primary and Efficient Simultaneous Presentation of and Danila

D. Speiser, P. Romero, D. Valmori, 2000 .

Enrichment of Human CD4+ Vα24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors 1

D. Speiser, P. Romero, N. Rufer, 2009, The Journal of Immunology.

Normal responsiveness of CTLA-4-deficient anti-viral cytotoxic T cells.

T. Mak, P. Waterhouse, D. Speiser, 1998, Journal of immunology.

Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.

D. Speiser, P. Romero, N. Rufer, 2009, Cancer research.

Publisher Correction: Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle

G. Ciriello, K. Mertz, Marco Mina, 2019, Nature Immunology.

High-throughput Screening of Human Tumor Antigen–specific CD4 T Cells, Including Neoantigen-reactive T Cells

G. Coukos, W. Reith, D. Speiser, 2019, Clinical Cancer Research.

High-throughput screening of human tumor-antigen specific CD4 T cells, 1 including neo-antigen reactive T cells

W. Reith, D. Speiser, P. Baumgaertner, 2019 .

Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.

D. Speiser, P. Romero, V. Cerundolo, 1999, International immunology.

Absence of co‐stimulation and not the intensity of TCR signaling is critical for the induction of T cell unresponsiveness in vivo

T. Mak, D. Speiser, M. Bachmann, 1999, European journal of immunology.

The HVEM network: new directions in targeting novel costimulatory/co-inhibitory molecules for cancer therapy.

D. Olive, D. Speiser, C. Pasero, 2012, Current opinion in pharmacology.

Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?

R. Dummer, D. Speiser, S. Goldinger, 2016, Journal of immunotherapy.

Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients—Report of a Phase I/IIa Clinical Trial

A. Legat, D. Speiser, P. Baumgaertner, 2015, Clinical Cancer Research.

Cancer immunotherapy drives implementation science in oncology

D. Speiser, L. Flatz, 2014, Human vaccines & immunotherapeutics.

CD28‐negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients

D. Speiser, P. Romero, V. Cerundolo, 1999, European journal of immunology.

Early drop of circulating T cells negatively correlates with the protective immune response to Yellow Fever vaccination

D. Speiser, Silvia A. Fuertes Marraco, A. Bovay, 2020, Human vaccines & immunotherapeutics.

Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.

J. Schrenzel, D. Speiser, P. Romero, 2007, The Journal of investigative dermatology.

That Can Home to Nonlymphoid Tissues Human Thymus Exports Naive CD8 T Cells

D. Speiser, P. Romero, N. Rufer, 2004 .

Intravesical Bacillus Calmette Guerin Combined with a Cancer Vaccine Increases Local T-Cell Responses in Non-muscle–Invasive Bladder Cancer Patients

D. Speiser, P. Romero, Y. Cerantola, 2016, Clinical Cancer Research.

Maf deficiency in T cells dysregulates Treg - TH17 balance leading to spontaneous colitis

D. Speiser, H. Bouzourène, G. Verdeil, 2019, Scientific Reports.

TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide‐induced deletion under limited conditions

T. Mak, D. Speiser, L. Nguyen, 2000, European journal of immunology.

Viral peptide specific cytotoxic T lymphocytes are of high avidity to host-MHC but only low avidity to donor-MHC after allogeneic bone marrow transplantation.

D. Speiser, D. Kyburz, 1995, Transplant immunology.

Vaccination of Melanoma Patients With Melan-A/Mart-1 Peptide and Klebsiella Outer Membrane Protein P40 as an Adjuvant

D. Speiser, P. Baumgaertner, P. Romero, 2009, Journal of immunotherapy.

29th Annual meeting of the Society for Immunotherapy of Cancer (SITC)

H. Kohrt, D. Speiser, W. Urba, 2015, Journal of Immunotherapy for Cancer.

MAGE-A3 and MAGE-A4 specific CD4+ T cells in head and neck cancer patients: detection of naturally acquired responses and identification of new epitopes

D. Speiser, P. Romero, P. Monnier, 2010, Cancer Immunology, Immunotherapy.

Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer

D. Speiser, P. Romero, S. Viatte, 2007, Cancer Immunology, Immunotherapy.

Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy.

L. Montaner, D. Speicher, C. Meyer, 2022, Cancer cell.

Immunosuppressive Mediators Impair Proinflammatory Innate Lymphoid Cell Function in Human Malignant Melanoma

D. Speiser, P. Romero, A. Ianaro, 2020, Cancer Immunology Research.

RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses.

R. Schlenk, D. Speiser, S. Gnjatic, 2008, Blood.

Identification of an SSX-2 Epitope Presented by Dendritic Cells to Circulating Autologous CD4+ T Cells1

S. Stevanović, Yao-Tseng Chen, D. Speiser, 2004, The Journal of Immunology.

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.

D. Speiser, P. Romero, M. Pittet, 2002, Trends in immunology.

CD4+ T Cell Responses to SSX-4 in Melanoma Patients1

S. Stevanović, Yao-Tseng Chen, D. Speiser, 2005, The Journal of Immunology.

CD4 T Cell Responses to SSX-4 in Melanoma Patients

S. Stevanović, Yao-Tseng Chen, D. Speiser, 2005 .

Melanoma Patients T Cell Responses to SSX-4 in + CD 4

S. Stevanović, Yao-Tseng Chen, D. Speiser, 2005 .

T cell responses are governed by avidity and co‐stimulatory thresholds

T. Mak, D. Speiser, T. Kündig, 1996, European journal of immunology.

CpG-ODN-induced sustained expression of BTLA mediating selective inhibition of human B cells

D. Olive, D. Speiser, E. Mamessier, 2013, Journal of Molecular Medicine.

Tumor Cell Recognition Efficiency by T Cells

D. Speiser, P. Romero, J. Cerottini, 2005, PLoS medicine.

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

M. Vogel, D. Speiser, M. Bachmann, 2019, Journal of Immunotherapy for Cancer.

Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

M. Vogel, D. Speiser, M. Bachmann, 2019, Journal of Immunotherapy for Cancer.

In situ delivery of nanoparticles formulated with micron-sized crystals protects from murine melanoma

D. Speiser, M. Kramer, Mona O. Mohsen, 2022, Journal for ImmunoTherapy of Cancer.

Sister cytotoxic CD8+ T cell clones differing in natural killer inhibitory receptor expression in human astrocytoma.

D. Speiser, P. Walker, G. Perrin, 2002, Immunology letters.

Molecular definition of severe acute respiratory syndrome coronavirus 2 receptor‐binding domain mutations: Receptor affinity versus neutralization of receptor interaction

M. Vogel, D. Speiser, M. Bachmann, 2021, Allergy.

Not All Tumor-Infiltrating CD8+ T Cells Are Created Equal.

D. Speiser, W. Held, 2021, Cancer cell.

A Novel Approach to Characterize Clonality and Differentiation of Human Melanoma-Specific T Cell Responses: Spontaneous Priming and Efficient Boosting by Vaccination1

D. Speiser, P. Corthésy, P. Baumgaertner, 2006, The Journal of Immunology.

T cells: Functional and molecular analysis of vaccine elicited T-cell responses in melanoma

D. Speiser, P. Baumgaertner, V. Voelter, 2008 .

An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain.

D. Speiser, A. Pica, V. Voelter, 2008, Cancer Immunity.

Can hTERT peptide (540-548) -specific CD8 T cells recognize and kill tumor cells?

D. Speiser, P. Romero, J. Cerottini, 2002, Cancer immunity.

Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle

G. Ciriello, K. Mertz, Marco Mina, 2019, Nature Immunology.

Anticancer Teamwork: Cross-Presenting Dendritic Cells Collaborate with Therapeutic Monoclonal Antibodies.

D. Speiser, C. Robert-Tissot, 2016, Cancer discovery.

The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.

D. Speiser, P. Romero, M. Colonna, 2001, Journal of immunology.

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.

A. Mackensen, D. Speiser, P. Romero, 2004, Cancer research.

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa

R. Zinkernagel, D. Speiser, H. Macdonald, 1989, The Journal of experimental medicine.

Tumor defense by murine cytotoxic T cells specific for peptide bound to nonclassical MHC class I.

D. Speiser, M. Bachmann, P. Ohashi, 1998, Cancer research.

Alloreactive cytotoxic T cells recognize minor transplantation antigens presented by major histocompatibility complex class Ib molecules.

D. Speiser, M. Bachmann, P. Ohashi, 1998, Transplantation.

Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists

D. Speiser, M. Bachmann, P. Ohashi, 1997, European journal of immunology.

Prognostic value of arginase‐II expression and regulatory T‐cell infiltration in head and neck squamous cell carcinoma

D. Speiser, P. Romero, P. Monnier, 2013, International journal of cancer.

Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo.

R. Zinkernagel, D. Speiser, H. Hengartner, 1993, Journal of immunology.

CpG-ODN-induced sustained expression of BTLA mediating selective inhibition of human B cells

D. Olive, D. Speiser, E. Mamessier, 2013, Journal of Molecular Medicine.

Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC

R. Zinkernagel, T. Rülicke, D. Speiser, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.

Danila Valmori, Pedro Romero, Philippe Guillaume, 2003, Cancer immunity.

Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism

D. Speiser, Mona O. Mohsen, Martin F Bachmann, 2022, NPJ vaccines.

Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer.

D. Speiser, B. Ludewig, J. Neefjes, 2019, JAMA oncology.

Pretransplant cytotoxic donor T‐cell activity specific to patient HLA class I antigens correlating with mortality after unrelated BMT

D. Speiser, M. Jeannet, C. Löliger, 1996, British journal of haematology.

HLA-B35-subtype mismatches in ABDR serologically matched unrelated donor-recipient pairs.

D. Speiser, N. Rufer, J. Tiercy, 1994, Human immunology.

Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells.

D. Speiser, P. Coulie, J. Tartaglia, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Human Effector CD8+ T Lymphocytes Express TLR3 as a Functional Coreceptor1

D. Speiser, P. Romero, N. Rufer, 2006, The Journal of Immunology.

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma

D. Hanahan, M. Swartz, D. Speiser, 2017, Science Translational Medicine.

COVID-19: Mechanisms of Vaccination and Immunity

D. Speiser, M. Bachmann, 2020, Vaccines.

Pretransplant rejection risk assessment through enzyme-linked immunosorbent assay analysis of anti-HLA class I antibodies.

D. Speiser, J. Kalil, R. Buelow, 1996, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Correlation of Elisa-Measured anti-HLA Class I IGG and IGG1 Antibodies and First-Year Rejection Episodes

D. Speiser, J. Kalil, R. Buelow, 1996 .

Virus‐like particles for vaccination against cancer

D. Speiser, M. Bachmann, A. Knuth, 2019, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma

D. Speiser, D. Hohl, J. Schaller, 2021, Oncotarget.

The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin

S. Werner, B. Ryffel, D. Speiser, 2020, Nature Immunology.

T cell–induced CSF1 promotes melanoma resistance to PD1 blockade

G. Coukos, Esther Danenberg, N. Wald, 2018, Science Translational Medicine.

Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells

C. Amos, A. Varki, H. Lenz, 2018, The Journal of clinical investigation.

Radioimmunotherapy Combined with Maintenance Anti-CD20 Antibody May Trigger Long-Term Protective T Cell Immunity in Follicular Lymphoma Patients

John O. Prior, S. Larson, D. Speiser, 2013, Clinical & developmental immunology.

Anti–CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response

S. H. van der Burg, T. Schumacher, M. Welters, 2014, Science Translational Medicine.

Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab

C. Meyer, D. Speiser, P. Baumgaertner, 2014, Cancer Immunology, Immunotherapy.

Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides.

D. Speiser, P. Romero, C. Jandus, 2008, Arthritis and rheumatism.

CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses

D. Speiser, P. Romero, R. Perret, 2012, Cancer Immunology, Immunotherapy.

Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

H. Pircher, A. Legat, D. Speiser, 2012, PloS one.

Pattern and clinical significance of cancer‐testis gene expression in head and neck squamous cell carcinoma

D. Speiser, P. Romero, P. Monnier, 2011, International journal of cancer.

De novo initiation codon mutation (ATG→ACG) of the β‐globin gene causing β‐thalassemia in a swiss family

D. Speiser, P. Beris, V. Kirchner, 1993 .

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

F. Martinon, P. Hwu, D. Speiser, 2015, Proceedings of the National Academy of Sciences.

Recent advances and hurdles in melanoma immunotherapy

D. Speiser, P. Romero, C. Jandus, 2009, Pigment cell & melanoma research.

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

D. Speiser, P. Romero, V. Cerundolo, 1999, The Journal of experimental medicine.

Regulatory circuits of T cell function in cancer

D. Speiser, Ping-Chih Ho, G. Verdeil, 2016, Nature Reviews Immunology.

Cutting Edge: Cytolytic Effector Function in Human Circulating CD8+ T Cells Closely Correlates with CD56 Surface Expression1

D. Speiser, P. Romero, M. Pittet, 2000, The Journal of Immunology.

Intratumoral Tcf1+PD‐1+CD8+ T Cells with Stem‐like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

Daniel E. Speiser, David Gfeller, Santiago J. Carmona, 2019, Immunity.

T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion

A. Legat, D. Speiser, L. Carrié, 2013, Nature Immunology.

T cell receptor alpha variable 12‐2 bias in the immunodominant response to Yellow fever virus

D. Speiser, A. Sewell, G. Dolton, 2017, European journal of immunology.

Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting

Santiago J. Carmona, G. Ciriello, G. Coukos, 2021, Cell reports. Medicine.

The role of exhaustion in CAR T cell therapy.

D. Speiser, C. Mackall, Greg M. Delgoffe, 2021, Cancer cell.

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

M. Swartz, L. Santambrogio, D. Speiser, 2019, The Journal of experimental medicine.

Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation.

M. Delorenzi, L. Tang, D. Speiser, 2020, Immunity.

Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma

Brian J. Stevenson, M. Vogel, G. Coukos, 2021, Journal for ImmunoTherapy of Cancer.

Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer

G. Coukos, W. Reith, J. Trapani, 2021, Science Advances.

Immune Monitoring of Blood and Tumor Microenvironment

D. Speiser, P. Baumgaertner, Kalliopi Ioannidou, 2018 .

From T cell "exhaustion" to anti-cancer immunity.

D. Speiser, G. Verdeil, Silvia A. Fuertes Marraco, 2016, Biochimica et biophysica acta.

Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8+ and CD4+ T-cell responses with multiple specificities including a novel DR7-restricted epitope

D. Speiser, P. Baumgaertner, P. Romero, 2016, Oncoimmunology.

Molecular Insights for Optimizing T Cell Receptor Specificity Against Cancer

D. Speiser, N. Rufer, D. Zehn, 2013, Front. Immunol..

Signaling Mechanisms that Balance Anti-viral, Auto-reactive, and Antitumor Potential of Low Affinity T Cells

D. Speiser, N. Rufer, D. Zehn, 2013 .

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.

Katie M. Campbell, V. Velculescu, P. Ross-Macdonald, 2020, Cancer cell.

The Activatory Receptor 2B4 Is Expressed In Vivo by Human CD8+ Effector αβ T Cells1

D. Speiser, P. Romero, M. Colonna, 2001, The Journal of Immunology.

A Regulatory Role for TRAF1 in Antigen-induced Apoptosis of T Cells

Soo Young Lee, D. Speiser, Y. Kong, 1997, The Journal of experimental medicine.

New approaches in metastatic melanoma: biological and molecular targeted therapies

D. Speiser, D. Rimoldi, F. Lejeune, 2007, Expert review of anticancer therapy.

Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients

R. Dummer, K. Schwarz, D. Speiser, 2010, Journal of immunotherapy.

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.

D. Goeddel, T. Mak, D. Speiser, 1997, Immunity.

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

C. Meyer, D. Speiser, P. Baumgaertner, 2015, Proceedings of the National Academy of Sciences.

Peptide‐induced T cell receptor down‐regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation

R. Zinkernagel, A. Oxenius, D. Speiser, 1997, European journal of immunology.

NFAT5 induction by the tumor microenvironment enforces CD8 T cell exhaustion

S. Carmona, I. Crespo, D. Speiser, 2022, bioRxiv.

Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients

M. Delorenzi, D. Speiser, P. Baumgaertner, 2021, Oncoimmunology.

Intratumoral CD8+ T cells with stem cell–like properties: Implications for cancer immunotherapy

D. Speiser, W. Held, I. Siddiqui, 2019, Science Translational Medicine.

Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets

Pedro Romero, Brigitte Autran, Victor Appay, 2011, Journal of Translational Medicine.

T memory stem cells in health and disease

Chiara Bonini, D. Speiser, M. Lichterfeld, 2017, Nature Medicine.

Consensus nomenclature for CD 8 T cell phenotypes in cancer

S. H. van der Burg, J. Blay, F. Marincola, 2015 .

A Well-Controlled Experimental System to Study Interactions of Cytotoxic T Lymphocytes with Tumor Cells

M. Delorenzi, D. Speiser, C. Soneson, 2016, Front. Immunol..

T-cell activation by treatment of cancer patients with EMD 521873 (Selectikine), an IL-2/anti-DNA fusion protein

R. Stupp, D. Speiser, C. Sessa, 2013, Journal of Translational Medicine.

Microangiopathy of cutaneous blood and lymphatic capillaries in chronic venous insufficiency (CVI).

A. Bollinger, P. Haselbach, D. Speiser, 1993, The Yale journal of biology and medicine.

IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28+ Cytolytic T Cells1

D. Speiser, P. Baumgaertner, P. Romero, 2007, The Journal of Immunology.

Cytolytic T Cells + of Self-Antigen-Specific Human CD 28 IL-12 Controls Cytotoxicity of a Novel Subset Rufer and

D. Speiser, P. Baumgaertner, P. Romero, 2007 .

Identification of tumor-associated antigens by large-scale analysis of genes expressed in human colorectal cancer.

C. V. Jongeneel, Brian J. Stevenson, D. Speiser, 2008, Cancer immunity.

Pulmonary sarcoid-like granulomatosis induced by ipilimumab.

S. Peters, D. Speiser, O. Michielin, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron

Gheyath K Nasrallah, M. Vogel, D. Speiser, 2022, bioRxiv.

ILC2-modulated T cell–to-MDSC balance is associated with bladder cancer recurrence

D. Speiser, D. Gfeller, Julien Racle, 2017, The Journal of clinical investigation.

Heterogeneity assessment of functional T cell avidity

D. Speiser, P. Baumgaertner, N. Rufer, 2017, Scientific Reports.

Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes1

Pedro Romero, Daniel E. Speiser, Nathalie Rufer, 2007, The Journal of Immunology.

Tcf7 effector cells in the absence of cytotoxic differentiation

M. Delorenzi, D. Speiser, T. Wyss, 2020 .

Broad and Conserved Immune Regulation by Genetically Heterogeneous Melanoma Cells.

M. Delorenzi, D. Speiser, C. Soneson, 2017, Cancer research.

High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation.

D. Speiser, N. Rufer, C. Grundschober, 1996, Blood.

Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients

R. Dummer, L. Risch, D. Speiser, 2019, Journal of Immunotherapy for Cancer.

Mobilizing and evaluating anticancer T cells: pitfalls and solutions

D. Speiser, L. Nguyen, P. Ohashi, 2013, Expert review of vaccines.

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

D. Speiser, P. Romero, V. Cerundolo, 1999, The Journal of experimental medicine.

Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex1

D. Speiser, P. Romero, M. Pittet, 2006, The Journal of Immunology.

Histoincompatibilities in ABDR-matched unrelated donor recipient combinations.

D. Speiser, N. Rufer, J. Tiercy, 1995, Bone marrow transplantation.

THE FREQUENCY OF PRETRANSPLANT DONOR CYTOTOXIC T CELL PRECURSORS WITH ANTI‐HOST SPECIFICITY PREDICTS SURVIVAL OF PATIENTS TRANSPLANTED WITH BONE MARROW FROM DONORS OTHER THAN HLA‐IDENTICAL SIBLINGS

D. Speiser, B. Chapuis, R. Seger, 1993, Transplantation.

TNF receptor p55 controls early acute graft-versus-host disease.

T. Mak, D. Speiser, M. Bachmann, 1997, Journal of immunology.

Human CD8+ T cells expressing HLA‐DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells

D. Speiser, P. Romero, M. Pittet, 2001, European journal of immunology.

Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

T. Schumacher, D. Speiser, J. Sarria, 2010, The Journal of Immunology.

Delimiting Maximal CD8 T Cell Function Evidence for a TCR Affinity Threshold

Schumacher, D. Speiser, J. Sarria, 2010 .

Post-Thymic Differentiation for CD4+ and Human T Cell Subsets Reveals Parallel Sensitive Gene Expression Profiling of

Pedro Romero, Serge Leyvraz, Daniel E. Speiser, 2013 .

Sensitive Gene Expression Profiling of Human T Cell Subsets Reveals Parallel Post-Thymic Differentiation for CD4+ and CD8+ Lineages1

V. Appay, A. Bosio, D. Speiser, 2007, The Journal of Immunology.

Does constant regulation of CD8 T cell functional avidity explain its stability?

D. Speiser, N. Rufer, Michael Hebeisen, 2021, European journal of immunology.

show telomerase activity and are distinct from cytolytic effector T cells

D. Speiser, P. Romero, D. Valmori, 2001 .

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides

Hans Hengartner, Peter Aichele, Hanspeter Pircher, 1993, European journal of immunology.

Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection.

R. Zinkernagel, D. Speiser, H. Hengartner, 1992, Journal of immunology.

IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

T. Mak, D. Speiser, A. Pandyra, 2014, Cell Death and Differentiation.

Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion

D. Speiser, Laurent Vanhille, Julien Maurizio, 2015, The EMBO journal.

BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination.

D. Olive, D. Speiser, P. Romero, 2010, The Journal of clinical investigation.

Pulmonary Sarcoid–like Granulomatosis after Multiple Vaccinations of a Long-term Surviving Patient with Metastatic Melanoma

D. Speiser, P. Baumgaertner, N. Rufer, 2014, Cancer Immunology Research.

Maf deficiency in T cells dysregulates Treg - TH17 balance leading to spontaneous colitis

D. Speiser, H. Bouzourène, D. Velin, 2019, Scientific Reports.

Relation between the resolution of HLA-typing and the chance of finding an unrelated bone marrow donor.

D. Speiser, N. Rufer, J. Tiercy, 1994, Bone marrow transplantation.

MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma

Santiago J. Carmona, S. Carmona, D. Speiser, 2019, Cancer Immunology Research.

SARS-CoV-2 structural features may explain limited neutralizing-antibody responses

M. Vogel, D. Speiser, M. Bachmann, 2021, NPJ vaccines.

T Cell Tolerance versus Tumor Immunity or Autoimmunity

D. Speiser, P. Ohashi, 1998 .

Inhibition of TCR triggering by a spectrum of altered peptide ligands suggests the mechanism for TCR antagonism

D. Speiser, M. Bachmann, P. Ohashi, 1998, European journal of immunology.

Functional management of an antiviral cytotoxic T-cell response

D. Speiser, M. Bachmann, P. Ohashi, 1997, Journal of virology.

Tetramer-Guided Analysis of TCR β-Chain Usage Reveals a Large Repertoire of Melan-A-Specific CD8+ T Cells in Melanoma Patients1

D. Speiser, P. Romero, V. Cerundolo, 2000, The Journal of Immunology.

Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients.

D. Speiser, P. Romero, D. Valmori, 2001, International immunopharmacology.

Genome-wide RNA profiling of long-lasting stem cell-like memory CD8 T cells induced by Yellow Fever vaccination in humans

M. Delorenzi, D. Speiser, C. Soneson, 2015, Genomics data.

Ex Vivo Analysis of Human Antigen-Specific CD8+ T-Cell Responses: Quality Assessment of Fluorescent HLA-A2 Multimer and Interferon-γ ELISPOT Assays for Patient Immune Monitoring

D. Speiser, P. Romero, M. Pittet, 2004, Journal of immunotherapy.

Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation.

T. Mak, D. Speiser, M. Bachmann, 1997, Immunity.

Human Effector CD 8 T Lymphocytes Express TLR 3 as a Functional Coreceptor 1

D. Speiser, P. Romero, N. Rufer, 2006 .

HLA-DRB1 matched kidneys are preferentially HLA-A and -B compatible and survive longer.

D. Speiser, J. Tiercy, M. Jeannet, 1994, Transplant immunology.

Fluorescence-Activated Cell Sorting and Cloning of Bona Fide CD8+ CTL with Reversible MHC-Peptide and Antibody Fab′ Conjugates1

D. Speiser, P. Baumgaertner, P. Guillaume, 2006, The Journal of Immunology.

The three main stumbling blocks for anticancer T cells.

C. Meyer, A. Legat, D. Speiser, 2012, Trends in immunology.

Neoantigen-targeted CD8^+ T cell responses with PD-1 blockade therapy

O. Griffith, M. Griffith, A. Ribas, 2023, Nature.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Identification of Multiple Mechanisms of Resistance to Vemurafenib in a Patient with BRAFV600E-Mutated Cutaneous Melanoma Successfully Rechallenged after Progression

S. Pradervand, K. Harshman, S. Peters, 2013, Clinical Cancer Research.

Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease

K. Mertz, D. Speiser, W. Jochum, 2017, Cancer Immunology, Immunotherapy.

High Peptide Dose Vaccination Promotes the Early Selection of Tumor Antigen-Specific CD8 T-Cells of Enhanced Functional Competence

D. Speiser, P. Baumgaertner, N. Rufer, 2020, Frontiers in Immunology.

Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients

D. Speiser, P. Romero, O. Michielin, 2007, Cancer Immunology, Immunotherapy.

Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses

D. Olive, D. Speiser, V. Zoete, 2017, PloS one.

The human T cell response to melanoma antigens.

D. Speiser, P. Romero, J. Cerottini, 2006, Advances in immunology.

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.

D. Speiser, P. Romero, N. Rufer, 2005, The Journal of clinical investigation.

Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Danila Valmori, Pedro Romero, Daniel E. Speiser, 2002, The Journal of experimental medicine.

Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle

G. Ciriello, K. Mertz, Marco Mina, 2019, Nature Immunology.

New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site1

V. Appay, D. Speiser, V. Voelter, 2006, The Journal of Immunology.

T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?

D. Speiser, P. Romero, C. Münz, 2014, Nature Reviews Immunology.

Deciphering the unusual HLA‐A2/Melan‐A/MART‐1‐specific TCR repertoire in humans

D. Speiser, P. Romero, N. Rufer, 2014, European journal of immunology.

Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity.

D. Speiser, P. Romero, 2010, Seminars in immunology.

Therapeutic cancer vaccines based on molecularly defined human tumor antigens.

D. Speiser, P. Romero, M. Pittet, 2002, Vaccine.

Murine CD8 T‐cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density

D. Irvine, D. Speiser, N. Rufer, 2019, European journal of immunology.

LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures

D. Speiser, I. Tirapu, G. Verdeil, 2020, Oncoimmunology.

SHP-1 phosphatase activity counteracts increased T cell receptor affinity.

D. Speiser, P. Baumgaertner, P. Romero, 2013, The Journal of clinical investigation.

Melanoma dedifferentiation induced by IFN- γ epigenetic remodeling in response to anti–PD-1 therapy

T. Graeber, C. Swanton, A. Ribas, 2021 .

Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge”, Napoli, December 5th 2015

F. Marincola, P. Ascierto, B. Fox, 2016, Journal of Immunotherapy for Cancer.

Molecular profiling of CD8T cells in autochthonous melanoma identifiesMafas driver of exhaustion

D. Speiser, Laurent Vanhille, Julien Maurizio, 2015 .

Circulation but Not in the Tumor Site T Cells in the + Melanoma-Specific CD8 New Generation Vaccine Induces Effective

D. Speiser, V. Voelter, P. Romero, 2015 .

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine

M. Vogel, D. Speiser, S. Salatino, 2019, Front. Immunol..

An immunodominant SSX-2-derived epitope recognized by CD4+ T cells in association with HLA-DR.

D. Speiser, L. Old, D. Valmori, 2004, The Journal of clinical investigation.

CD40 Agonist Restores the Antitumor Efficacy of Anti-PD1 Therapy in Muscle-Invasive Bladder Cancer in an IFN I/II-Mediated Manner

D. Speiser, C. Ries, G. Verdeil, 2020, Cancer Immunology Research.

T cell responses are governed by avidity and costimulatory thresholds

T. Mak, D. Speiser, M. Bachmann, 1996 .

Preferential positive selection of Vα2+CD8+ T cells in mouse strains expressing both H‐2k and T cell receptor Vαa haplotypes: determination with a Vα2‐specific monoclonal antibody

H. Pircher, R. Zinkernagel, D. Speiser, 1992, European journal of immunology.

A Novel Population of Human Melanoma-Specific CD8 T Cells Recognizes Melan-AMART-1 Immunodominant Nonapeptide but Not the Corresponding Decapeptide1

Olivier Michielin, Vincent Zoete, Pedro Romero, 2007, The Journal of Immunology.

Discrepancy between ELISPOT IFN-γ secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life

D. Speiser, P. Romero, D. Valmori, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens

D. Speiser, N. Rufer, M. Allard, 2015, Front. Immunol..

Distinct but overlapping T helper epitopes in the 37-58 region of SSX-2.

S. Stevanović, Yao-Tseng Chen, D. Speiser, 2005, Clinical immunology.

MelanomaTumor-Reactive CTL Infiltrating Metastatic SSX-2-Derived Epitope Recognized by Proteasome-Assisted Identification of a

H. Rammensee, S. Stevanović, M. Pfreundschuh, 2002 .

Decapeptide Nonapeptide but Not the Corresponding ImmunodominantMART-1 MelanA Melanoma-Specific CD 8 T Cells Recognizes A Novel Population of Human

D. Speiser, P. Romero, V. Zoete, 2007 .

Title : Deciphering the unusual HLA-A 2 / MelanA / MART-1-specific TCR repertoire in humans

D. Speiser, 2022 .

Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose

D. Speiser, P. Baumgaertner, N. Rufer, 2012, Cancer Immunology, Immunotherapy.

Toward improved immunocompetence of adoptively transferred CD8+ T cells.

D. Speiser, P. Romero, 2005, The Journal of clinical investigation.

Profile of a Serial Killer: Cellular and Molecular Approaches to Study Individual Cytotoxic T-Cells following Therapeutic Vaccination

D. Speiser, P. Baumgaertner, N. Rufer, 2010, Journal of biomedicine & biotechnology.

Constant regulation for stable CD8 T‐cell functional avidity and its possible implications for cancer immunotherapy

D. Speiser, N. Rufer, Michael Hebeisen, 2021, European Journal of Immunology.

Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b 214-222 by combinatorial peptide library screening.

D. Speiser, V. Zoete, P. Rizkallah, 2020, Molecular immunology.

TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.

D. Speiser, P. Romero, N. Rufer, 2017, JCI insight.

Fine Structural Variations of αβTCRs Selected by Vaccination with Natural versus Altered Self-Antigen in Melanoma Patients1

D. Speiser, P. Corthésy, P. Baumgaertner, 2009, The Journal of Immunology.

Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival

D. Speiser, B. Ludewig, P. Baumgaertner, 2021, Oncoimmunology.

Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination

D. Speiser, P. Romero, J. Cerottini, 2004, Cancer Immunology, Immunotherapy.

Reversible Major Histocompatibility Complex I-Peptide Multimers Containing Ni2+-Nitrilotriacetic Acid Peptides and Histidine Tags Improve Analysis and Sorting of CD8+ T Cells*

D. Speiser, P. Baumgaertner, P. Guillaume, 2011, The Journal of Biological Chemistry.

Impact of Orthologous Melan-A Peptide Immunizations on the Anti-Self Melan-A/HLA-A2 T Cell Cross-Reactivity1

D. Speiser, N. Rufer, O. Michielin, 2006, The Journal of Immunology.

Melan-A/HLA-A2 T Cell Cross-Reactivity Immunizations on the Anti-Self Impact of Orthologous Melan-A Peptide

D. Speiser, N. Rufer, O. Michielin, 2006 .

Melan-A / HLA-A 2 T Cell Cross-Reactivity Immunizations on the Anti-Self Impact of Orthologous MelanA Peptide

D. Speiser, N. Rufer, O. Michielin, 2006 .

Circulating CD56bright NK cells inversely correlate with survival of melanoma patients

D. Speiser, P. Baumgaertner, Kaat de Jonge, 2019, Scientific Reports.

α3 Domain Mutants of Peptide/MHC Class I Multimers Allow the Selective Isolation of High Avidity Tumor-Reactive CD8 T Cells1

D. Speiser, P. Romero, M. Pittet, 2003, The Journal of Immunology.

Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+ T Cell Responsiveness*

Olivier Michielin, Vincent Zoete, Pedro Romero, 2012, The Journal of Biological Chemistry.

Microtubule-Depolymerizing Agents Used in Antibody–Drug Conjugates Induce Antitumor Immunity by Stimulation of Dendritic Cells

D. Speiser, S. Dirnhofer, S. Theurich, 2014, Cancer Immunology Research.

by Vaccination Spontaneous Priming and Efficient Boosting Melanoma-Specific T Cell Responses: and Differentiation of Human A Novel Approach to Characterize Clonality

D. Speiser, P. Corthésy, P. Baumgaertner, 2006 .

Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide

V. Appay, C. Pinilla, D. Speiser, 2006, European journal of immunology.

Decreased specific CD 8 + T cell cross-reactivity of antigen recognition following vaccination with MelanA peptide

V. Appay, C. Pinilla, D. Speiser, 2006 .

Dendritic cells direct circadian anti-tumour immune responses

D. Speiser, M. Pittet, C. Scheiermann, 2022, Nature.

A phase I dose-escalation study of the immunocytokine EMD 521873 (Selectikine) in patients with advanced solid tumours.

R. Stupp, D. Speiser, C. Sessa, 2013, European journal of cancer.

Distinct sets of αβ TCRs confer similar recognition of tumor antigen NY-ESO-1157–165 by interacting with its central Met/Trp residues

D. Speiser, P. Baumgaertner, P. Romero, 2008, Proceedings of the National Academy of Sciences.

Degeneracy instead of specificity: is this a solution to cancer immunotherapy?

D. Speiser, P. Romero, M. Pittet, 2002 .

An infrared spectral signature of human lymphocyte subpopulations from peripheral blood.

E. Goormaghtigh, N. Wald, C. Meyer, 2015, The Analyst.

Yellow fever virus vaccination: an emblematic model to elucidate robust human immune responses

D. Speiser, Silvia A. Fuertes Marraco, A. Bovay, 2021, Human vaccines & immunotherapeutics.

Melanoma dedifferentiation induced by interferon-gamma epigenetic remodeling in response to anti-PD-1 therapy.

T. Graeber, A. Hoffmann, C. Swanton, 2021, The Journal of clinical investigation.

CD4+ T cells in cancer

D. Speiser, C. Münz, Obinna Chijioke, 2023, Nature Cancer.

TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs

G. Coukos, D. Speiser, P. Baumgaertner, 2023, Cell reports methods.

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.

Katie M. Campbell, V. Velculescu, P. Ross-Macdonald, 2020, Cancer cell.

Circulating CD56bright NK cells inversely correlate with survival of melanoma patients

D. Speiser, P. Baumgaertner, Kaat de Jonge, 2019, Scientific Reports.

Disulfide-Linked Peptides for Blocking BTLA/HVEM Binding

Adam K. Sieradzan, Agnieszka S. Karczynska, D. Speiser, 2020, International journal of molecular sciences.

A scalable and highly immunogenic virus‐like particle‐based vaccine against SARS‐CoV‐2

M. Vogel, D. Speiser, T. Kündig, 2021, Allergy.

Human T cell dynamics in vivo are compatible with long-lived immunological memory and stemness

D. Speiser, K. Ladell, B. Asquith, 2018 .

Virus‐like particles induce robust human T‐helper cell responses

K. Schwarz, D. Speiser, P. Romero, 2012, European journal of immunology.

Frequent MAGE Mutations in Human Melanoma

Lloyd J. Old, Olivier Michielin, Jedd D. Wolchok, 2010, PloS one.

Cysteine-rich Domain 1 of CD40 Mediates Receptor Self-assembly*

D. Speiser, P. Schneider, C. Smulski, 2013, The Journal of Biological Chemistry.

The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin

B. Ryffel, D. Speiser, J. Di Domizio, 2020, Nature Immunology.

Efficient homologous prime‐boost strategies for T cell vaccination based on virus‐like particles

K. Schwarz, D. Speiser, A. Tissot, 2005, European journal of immunology.

Simultaneous Coexpression of Memory-related and Effector-related Genes by Individual Human CD8 T Cells Depends on Antigen Specificity and Differentiation

D. Speiser, N. Rufer, Sébastien Wieckowski, 2012, Journal of immunotherapy.

Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes

D. Speiser, P. Baumgaertner, P. Romero, 2011, Proceedings of the National Academy of Sciences.

Dominant Human CD8 T Cell Clonotypes Persist Simultaneously as Memory and Effector Cells in Memory Phase1

D. Speiser, P. Corthésy, P. Romero, 2009, The Journal of Immunology.

Human Thymus Exports Naive CD8 T Cells That Can Home to Nonlymphoid Tissues1

D. Speiser, P. Romero, N. Rufer, 2004, The Journal of Immunology.

Linking Viral DNA to Endosomal Innate Immune Recognition.

D. Speiser, Martin F Bachmann, 2023, Journal of immunology.

Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation

M. Vogel, D. Speiser, A. Zeltiņš, 2023, Frontiers in Immunology.

Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins

R. Zinkernagel, M. Battegay, D. Speiser, 1993, European journal of immunology.

In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration1

H. Pircher, D. Speiser, P. Corthésy, 2007, The Journal of Immunology.

Characterization of pretransplant CTL activity in "perfectly matched" unrelated bone marrow donor/recipient combinations.

D. Speiser, N. Rufer, J. Tiercy, 1993, Bone marrow transplantation.

Title: Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients–Report

A. Legat, D. Speiser, P. Baumgaertner, 2022 .

FcgRIIIA (CD16)-expressing monocytes mediate the depletion of tumor-infiltrating Tregs via Ipilimumab-dependent ADCC in melanoma patients

C. Meyer, D. Speiser, P. Baumgaertner, 2014, Journal of Immunotherapy for Cancer.

T Cells in Tumor Immunity

D. Speiser, P. Romero, M. Pittet, 2003 .

Minimal immune response to booster vaccination against Yellow Fever associated with pre-existing antibodies.

R. Ahmed, Rama S. Akondy, D. Speiser, 2020, Vaccine.

Combination of Transient Lymphodepletion With Busulfan and Fludarabine and Peptide Vaccination in a Phase I Clinical Trial for Patients With Advanced Melanoma

V. Appay, D. Speiser, V. Voelter, 2007, Journal of immunotherapy.

T-cell immunoincompetence in allogeneic chimerism.

R. Zinkernagel, D. Speiser, M. Jeannet, 1992, The New England journal of medicine.

Fast , long-range , reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer

D. Speiser, P. Baumgaertner, V. Voelter, 2008 .

HETEROGENEITY OF HLA‐B35: OLIGOTYPING AND DIRECT SEQUENCING FOR B35 SUBTYPES REVEALS A HIGH MISMATCHING RATE IN B35 SEROLOGICALLY COMPATIBLE KIDNEY AND BONE MARROW DONOR/RECIPIENT PAIRS

D. Speiser, N. Rufer, J. Tiercy, 1995, Transplantation.

Molecular definition of SARS-CoV-2 RBD mutations: receptor affinity versus neutralization of receptor interaction

M. Vogel, D. Speiser, Mona O. Mohsen, 2021 .

SARS-CoV-2 variant with higher affinity to ACE2 shows reduced sera neutralization susceptibility

M. Vogel, D. Speiser, M. Bachmann, 2021, bioRxiv.

Extrathymic positive selection of alpha beta T-cell precursors in nude mice.

R. Zinkernagel, D. Speiser, U. Stübi, 1992, Nature.

Analysis of cancer cell-intrinsic immune regulation in response to CD8+ T cell attack.

D. Speiser, Silvia A. Fuertes Marraco, N. Neubert, 2020, Methods in enzymology.

Molecular definition of SARS-CoV-2 RBD mutations: receptor affinity versus neutralization of receptor interaction.

M. Vogel, D. Speiser, M. Bachmann, 2021, Allergy.

Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis.

D. Speiser, M. Bachmann, P. Ohashi, 1997, Journal of immunology.

Coexistence of multiple escape mechanisms in a BRAFV600E-mutated cutaneous melanoma treated with vemurafenib.

S. Pradervand, K. Harshman, S. Peters, 2013 .

The C-terminal extension landscape of naturally presented HLA-I ligands

G. Coukos, D. Speiser, P. Baumgaertner, 2017, Proceedings of the National Academy of Sciences.

Melan-A/MART-1: Immunogenicity and vaccine strategies

D. Speiser, P. Romero, J. Cerottini, 2003 .

Statement of Principles for Health Care Journalists

D. Speiser, G. Schwitzer, J. Cerottini, 2005 .

Inhibition of TCR triggering by a spectrum of altered peptide ligands suggests the mechanism for TCR antagonism

D. Speiser, M. Bachmann, P. Ohashi, 1998, European journal of immunology.

Conference scene: Immune signatures in the tumor and beyond.

G. Coukos, C. Melief, D. Speiser, 2012, Immunotherapy.

Statement of Principles for Health Care Journalists

Hyuk-Jae Chang, D. Speiser, Sang-Eun Lee, 2005 .

Statement of Principles for Health Care Journalists

M. Gatz, D. Speiser, J. Cerottini, 2005 .

Cholesterol, Statins, and Alzheimer Disease

D. Speiser, J. Cerottini, P. Romero, 2005, PLoS medicine.

Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

H. Pircher, A. Legat, D. Speiser, 2012, PLoS ONE.

Drug-induced acute pancreatitis: further criticism.

D. Speiser, F. Largiadèr, D. Bimmler, 1993, Digestive diseases.

R. Zinkernagel, D. Speiser, H. Macdonald, 1990, The Journal of experimental medicine.

- mutated cutaneous melanoma successfully rechallenged after initial progression

S. Pradervand, K. Harshman, S. Peters, 2013 .

Classification of Current Anticancer Immunotherapies Classification of Current Anticancer Immunotherapies , Maha Ayyoub , Philipp Beckhove , Chiara Castelli

S. H. van der Burg, A. Palucka, M. Dhodapkar, 2022 .

Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion

D. Speiser, Laurent Vanhille, Julien Maurizio, 2015, The EMBO journal.

Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors

Brian J. Stevenson, G. Coukos, D. Speiser, 2023, Nature communications.

The human CD8 T stem cell-like memory phenotype appears in the acute phase in Yellow Fever virus vaccination

D. Speiser, W. Held, Hajer Ouertatani-Sakouhi, 2019 .

Shared acute phase traits in effector and memory human CD8 T cells

M. Delorenzi, B. Deplancke, D. Speiser, 2021, Current research in immunology.

Correction: Frequent MAGE Mutations in Human Melanoma

Brian J. Stevenson, R. Strausberg, A. Simpson, 2010, PLoS ONE.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

High Frequencies of Naive Melan-A/MART-1–speciﬁc CD8 (cid:49) T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (HLA)-A2 Individuals

D. Speiser, D. Valmori, J. Cerottini, 1999 .

High Frequencies of Naive Melan-A/MART-1–speciﬁc CD8 (cid:49) T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (HLA)-A2 Individuals

D. Speiser, D. Valmori, J. Cerottini, 1999 .

Microtubule-Depolymerizing Agents Used in Antibody–Drug Conjugates Induce Antitumor Immunity by Stimulation of Dendritic Cells

D. Speiser, S. Dirnhofer, S. Theurich, 2014, Cancer Immunology Research.

Immunoregulation of Dendritic Cell Subsets by Inhibitory Receptors in Urothelial Cancer.

B. Lhermitte, D. Speiser, L. de Leval, 2017, European urology.

The C-terminal extension landscape of naturally presented HLA-I ligands

G. Coukos, D. Speiser, D. Gfeller, 2017, Proceedings of the National Academy of Sciences.

Hugh Robson MacDonald (1946-2023).

D. Speiser, W. Held, I. Ferrero, 2023, Immunity.

Reversible Major Histocompatibility Complex I-Peptide Multimers Containing Ni2+-Nitrilotriacetic Acid Peptides and Histidine Tags Improve Analysis and Sorting of CD8+ T Cells*

D. Speiser, P. Guillaume, I. Luescher, 2011, The Journal of Biological Chemistry.

Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

D. Speiser, D. Gfeller, Julien Racle, 2017, bioRxiv.