P. Froment

发表

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.

S. Francoz, P. Froment, S. Bogaerts, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Adenosine 5'-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells.

P. Froment, J. Dupont, L. Tosca, 2005, Endocrinology.

Adipokines Expression and Effects in Oocyte Maturation, Fertilization and Early Embryo Development: Lessons from Mammals and Birds

P. Froment, J. Dupont, C. Ramé, 2020, International journal of molecular sciences.

Food restriction but not fish oil increases fertility in hens: role of RARRES2?

P. Froment, J. Dupont, C. Ramé, 2018, Reproduction.

Adipokines in metabolic and reproductive functions in birds: An overview of current knowns and unknowns

P. Froment, J. Dupont, Y. Bigot, 2021, Molecular and Cellular Endocrinology.

Expanding Duplication of Free Fatty Acid Receptor-2 (GPR43) Genes in the Chicken Genome

Pascal G. P. Martin, S. Lagarrigue, P. Froment, 2015, Genome biology and evolution.

Toxicity of Fumonisins, Deoxynivalenol, and Zearalenone Alone and in Combination in Turkeys Fed with the Maximum European Union-Tolerated Level.

P. Froment, S. Labrut, P. Guerre, 2019, Avian diseases.

The Insulin-like Growth Factor Axis in Cell Cycle Progression

P. Froment, J. Dupont, C. Moreau, 2003, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Differential proliferation and metabolic activity of Sertoli cells in the testes of broiler and layer breeder chickens

P. Froment, S. Crochet, A. Collin, 2017, Poultry science.

The 5’-AMP-Activated Protein Kinase (AMPK) Is Involved in the Augmentation of Antioxidant Defenses in Cryopreserved Chicken Sperm

P. Froment, Y. Combarnous, Thi Mong Diep Nguyen, 2015, PloS one.

Involvement of Novel Adipokines, Chemerin, Visfatin, Resistin and Apelin in Reproductive Functions in Normal and Pathological Conditions in Humans and Animal Models

P. Froment, J. Dupont, C. Ramé, 2019, International journal of molecular sciences.

Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN.

P. Froment, D. Nègre, J. Dupont, 2009, Human reproduction.

Reproductive biology Role of adiponectin receptors , AdipoR 1 and AdipoR 2 , in the steroidogenesis of the human granulosa tumor cell line , KGN

P. Froment, D. Nègre, J. Dupont, 2009 .

The adiponectin agonist, AdipoRon, inhibits steroidogenesis and cell proliferation in human luteinized granulosa cells

P. Froment, J. Dupont, C. Ramé, 2020, Molecular and Cellular Endocrinology.

A grape seed extract maternal dietary supplementation in reproductive hens reduces oxidative stress associated to modulation of plasma and tissue adipokines expression and improves viability of offsprings

P. Froment, C. Staub, A. Riva, 2020, PloS one.

Ovarian Expression of Adipokines in Polycystic Ovary Syndrome: A Role for Chemerin, Omentin, and Apelin in Follicular Growth Arrest and Ovulatory Dysfunction?

P. Froment, J. Dupont, C. Ramé, 2019, International journal of molecular sciences.

Involvement of adipokines, AMPK, PI3K and the PPAR signaling pathways in ovarian follicle development and cancer.

P. Froment, J. Dupont, C. Ramé, 2012, The International journal of developmental biology.

A grape seed extract maternal dietary supplementation improves egg quality and reduces ovarian steroidogenesis without affecting fertility parameters in reproductive hens

P. Froment, A. Riva, J. Dupont, 2020, PloS one.

A grape seed extract maternal dietary supplementation improves egg quality and reduces ovarian steroidogenesis without affecting fertility parameters in reproductive hens: a link with plasma and ovarian cell adipokines expression?

P. Froment, A. Riva, J. Dupont, 2020 .

ff ects of Grape Seed Extract and Proanthocyanidin B 2 on In Vitro Proliferation , Viability , Steroidogenesis , Oxidative Stress , and Cell Signaling in Human Granulosa Cells

P. Froment, A. Riva, J. Dupont, 2019 .

Effects of Grape Seed Extract and Proanthocyanidin B2 on In Vitro Proliferation, Viability, Steroidogenesis, Oxidative Stress, and Cell Signaling in Human Granulosa Cells

P. Froment, A. Riva, J. Dupont, 2019, International journal of molecular sciences.

Inactivation of AMPK alpha 1 Induces Asthenozoospermia and Alters Spermatozoa Morphology

B. Viollet, P. Froment, J. Dupont, 2020 .

Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality

B. Viollet, P. Froment, J. Dupont, 2016, Molecular and Cellular Endocrinology.

Chronic Dietary Exposure of Roosters to a Glyphosate-Based Herbicide Increases Seminal Plasma Glyphosate and AMPA Concentrations, Alters Sperm Parameters, and Induces Metabolic Disorders in the Progeny

P. Froment, J. Dupont, C. Ramé, 2021, Toxics.

Metformin Improves Quality of Post-Thaw Canine Semen

P. Froment, E. Jeanpierre, Anthony Estienne, 2020, Animals : an open access journal from MDPI.

Effect of metformin on the fertilizing ability of mouse spermatozoa.

P. Froment, M. Bertoldo, E. Guibert, 2014, Cryobiology.

Metformin exposure affects human and mouse fetal testicular cells.

N. Frydman, R. Frydman, P. Froment, 2012, Human reproduction.

Apelin and chemerin receptors are G protein-coupled receptors involved in metabolic as well as reproductive functions: Potential therapeutic implications?

P. Froment, J. Dupont, Anthony Estienne, 2021 .

Chemerin Impairs In Vitro Testosterone Production, Sperm Motility, and Fertility in Chicken: Possible Involvement of Its Receptor CMKLR1

P. Froment, J. Dupont, C. Ramé, 2020, Cells.

The Hepatokine FGF21 Increases the Human Spermatozoa Motility

P. Froment, J. Dupont, C. Ramé, 2022, Frontiers in Endocrinology.

CHEMERIN (RARRES2) Decreases In Vitro Granulosa Cell Steroidogenesis and Blocks Oocyte Meiotic Progression in Bovine Species 1 Running Title: CHEMERIN OR RARRES2 IN BOVINE FOLLICLES

P. Froment, C. Ramé, M. Bertoldo, 2014 .

CHEMERIN (RARRES2) Decreases In Vitro Granulosa Cell Steroidogenesis and Blocks Oocyte Meiotic Progression in Bovine Species1

P. Froment, J. Dupont, C. Ramé, 2014, Biology of reproduction.

Reproductive abnormalities in human IGF binding protein-1 transgenic female mice.

P. Froment, P. Monget, D. Monniaux, 2002, Endocrinology.

Perinatal Exposure to Methoxychlor Affects Reproductive Function and Sexual Behavior in Mice

P. Froment, M. Keller, I. Franceschini, 2020, Frontiers in Endocrinology.

Functional Alteration of the Somatotrophic Axis in Transgenic Mice with Liver-Specific Expression of Human Insulin-like Growth Factor Binding Protein-1

P. Froment, P. Monget, M. Binoux, 2002, Pediatric Research.

Expression of adiponectin, chemerin and visfatin in plasma and different tissues during a laying season in turkeys

P. Froment, J. Dupont, C. Ramé, 2015, Reproductive Biology and Endocrinology.

High androgen concentrations in follicular fluid of polycystic ovary syndrome women

P. Froment, J. Dupont, C. Ramé, 2022, Reproductive Biology and Endocrinology.

Reproductive abnormalities in human insulin-like growth factor-binding protein-1 transgenic male mice.

L. Johnson, P. Froment, C. Staub, 2004, Endocrinology.

Expression of adenosine 5'-monophosphate-Activated protein kinase (AMPK) in ovine testis (Ovis aries): In vivo regulation by nutritional state.

P. Froment, J. Dupont, C. Ramé, 2017, Animal reproduction science.

How does apelin affect LH levels? An investigation at the level of GnRH and KNDy neurons

P. Froment, C. Knauf, A. Abot, 2022, Molecular and Cellular Endocrinology.

Chronic dietary exposure to a glyphosate-based herbicide results in reversible increase early embryo mortality in chicken.

P. Froment, J. Dupont, C. Ramé, 2022, Ecotoxicology and environmental safety.

Apelin (APLN) regulates progesterone secretion and oocyte maturation in bovine ovarian cells.

P. Froment, J. Dupont, C. Ramé, 2017, Reproduction.

Reproductive Abnormalities in Human IGF Binding Protein-1 Transgenic Female Mice.

P. Froment, P. Monget, D. Monniaux, 2002, Endocrinology.

Ghrelin in Female and Male Reproduction

P. Froment, J. Dupont, C. Ramé, 2010, International journal of peptides.

Maternal dietary supplementation with grape seed extract in reproductive hens increases fertility in females but decreases semen quality in males of the F1 generation

P. Froment, A. Riva, J. Dupont, 2021, PloS one.

Expression of Dominant-Negative Thyroid Hormone Receptor Alpha1 in Leydig and Sertoli Cells Demonstrates No Additional Defect Compared with Expression in Sertoli Cells Only

P. Froment, G. Livera, P. Monget, 2015, PloS one.

Chemerin impairs food intake and body weight in chicken: focus on hypothalamic neuropeptides gene expression and AMPK signaling pathway.

P. Froment, M. Migaud, J. Dupont, 2021, General and comparative endocrinology.

Chronic dietary exposure to a glyphosate-based herbicide results in total or partial reversibility of plasma oxidative stress, cecal microbiota abundance and short-chain fatty acid composition in broiler hens

P. Froment, C. Staub, J. Dupont, 2022, Frontiers in Physiology.

The influence of selection in wild pheasant (Phasianus colchicus) breeding on reproduction and the involvement of the chemerin system

P. Froment, J. Dupont, C. Ramé, 2022, Poultry science.

Possible involvement of the RARRES2/CMKLR1-system in metabolic and reproductive parameters in Holstein dairy cows

P. Froment, J. Dupont, C. Ramé, 2019, Reproductive Biology and Endocrinology.

Endocrine effects of lifelong exposure to low-dose depleted uranium on testicular functions in adult rat.

P. Froment, M. Souidi, L. Manens, 2016, Toxicology.

Lack of Toxic Interaction between Fusariotoxins in Broiler Chickens Fed throughout Their Life at the Highest Level Tolerated in the European Union

P. Froment, S. Labrut, P. Guerre, 2019, Toxins.

Specific Deletion of AMP-Activated Protein Kinase (α1AMPK) in Murine Oocytes Alters Junctional Protein Expression and Mitochondrial Physiology

B. Viollet, P. Froment, J. Dupont, 2015, PloS one.

Chemerin is secreted by the chicken oviduct, accumulates in egg albumen and could promote embryo development

P. Froment, J. Dupont, C. Ramé, 2022, Scientific Reports.

Expression and effect of resistin on bovine and rat granulosa cell steroidogenesis and proliferation.

P. Froment, J. Dupont, C. Ramé, 2011, Reproduction.

Review: Mechanisms of Glyphosate and Glyphosate-Based Herbicides Action in Female and Male Fertility in Humans and Animal Models

P. Froment, J. Dupont, C. Vasseur, 2021, Cells.

PTEN expression in ovine granulosa cells increases during terminal follicular growth

P. Froment, J. Dupont, P. Monget, 2005, FEBS letters.

Toxic Effects of Fumonisins, Deoxynivalenol and Zearalenone Alone and in Combination in Ducks Fed the Maximum EUTolerated Level

P. Froment, S. Labrut, P. Guerre, 2021, Toxins.

Chicken white egg chemerin as a tool for genetic selection for egg weight and hen fertility

P. Froment, J. Dupont, C. Ramé, 2022, Frontiers in Physiology.

The insulin sensitiser metformin regulates chicken Sertoli and germ cell populations.

P. Froment, J. Dupont, C. Ramé, 2016, Reproduction.

Use of computed tomography to determine body composition of heavy strain turkey hens (Meleagris gallopavo) from rearing to early laying

P. Froment, F. Lecompte, S. Brière, 2018, Poultry science.

Inactivation of the IGF-I receptor gene in primary Sertoli cells highlights the autocrine effects of IGF-I.

P. Froment, D. Nègre, M. Holzenberger, 2007, The Journal of endocrinology.

An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential.

P. Froment, R. Habert, A. Legendre, 2010, Biomaterials.

Progress and challenges in developing organoids in farm animal species for the study of reproduction and their applications to reproductive biotechnologies

P. Froment, M. Flores, M. Saint-Dizier, 2021, Veterinary Research.

Characterization of chicken Sertoli cells in vitro.

P. Froment, J. Brillard, R. Pelletier, 2011, Poultry science.

Metformin in Reproductive Biology

P. Froment, C. Giulivi, J. Dupont, 2018, Front. Endocrinol..

Impact of metformin on reproductive tissues: an overview from gametogenesis to gestation.

P. Froment, J. Dupont, M. Bertoldo, 2014, Annals of translational medicine.

Inactivation of AMPKα1 induces asthenozoospermia and alters spermatozoa morphology.

B. Viollet, P. Froment, J. Dupont, 2012, Endocrinology.

In Utero Exposure to Metformin Reduces the Fertility of Male Offspring in Adulthood

I. Fournier, P. Froment, M. Guerquin, 2021, Frontiers in Endocrinology.

Chicken Is a Useful Model to Investigate the Role of Adipokines in Metabolic and Reproductive Diseases

P. Froment, J. Dupont, C. Ramé, 2018, International journal of endocrinology.

Ankrd31 in Sperm and Epididymal Integrity

P. Froment, L. Beauclair, R. Chianese, 2021, Frontiers in Cell and Developmental Biology.

Nutritional signals and reproduction

P. Froment, J. Dupont, M. Bertoldo, 2014, Molecular and Cellular Endocrinology.

Expression and Functional Role of Peroxisome Proliferator-Activated Receptor-γ in Ovarian Folliculogenesis in the Sheep1

P. Froment, J. Dupont, P. Monget, 2003, Biology of reproduction.

Energy sensors and reproductive hypothalamo-pituitary ovarian axis (HPO) in female mammals: Role of mTOR (mammalian target of rapamycin), AMPK (AMP-activated protein kinase) and SIRT1 (Sirtuin 1)

P. Froment, J. Dupont, C. Ramé, 2020, Molecular and Cellular Endocrinology.

Insulin-like growth factor binding protein-6 transgenic mice: postnatal growth, brain development, and reproduction abnormalities.

P. Froment, P. Monget, Y. Le Bouc, 2004, Endocrinology.

Distinct roles of Mdm2 and Mdm4 in red cell production.

U. Klingmuller, S. Francoz, P. Froment, 2007, Blood.

Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival

P. Froment, J. Dupont, Jean Christophe-Marine, 2008, Cell cycle.

Mechanisms of Adiponectin Action in Fertility: An Overview from Gametogenesis to Gestation in Humans and Animal Models in Normal and Pathological Conditions

P. Froment, J. Dupont, A. Rak, 2019, International journal of molecular sciences.

The Luteinizing Hormone-releasing Hormone Inhibits the Anti-apoptotic Activity of Insulin-like Growth Factor-1 in Pituitary αT3 Cells by Protein Kinase Cα-mediated Negative Regulation of Akt*

P. Froment, M. Quon, D. Leroith, 2004, Journal of Biological Chemistry.

Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells1

P. Froment, J. Dupont, C. Ramé, 2016, Biology of reproduction.

VISFATIN (NAMPT) Improves In Vitro IGF1-Induced Steroidogenesis and IGF1 Receptor Signaling Through SIRT1 in Bovine Granulosa Cells1

P. Froment, J. Dupont, C. Ramé, 2016, Biology of reproduction.

Running title: VISFATIN or NAMPT in bovine follicles

P. Froment, J. Dupont, C. Ramé, 2016 .

Expression and Regulation of INTELECTIN1 in Human Granulosa-Lutein Cells: Role in IGF-1-Induced Steroidogenesis Through NAMPT1

P. Froment, J. Dupont, C. Ramé, 2014, Biology of reproduction.

AMPK: a master energy regulator for gonadal function

P. Froment, J. Dupont, M. Bertoldo, 2015, Front. Neurosci..

Adiponectin and resistin: potential metabolic signals affecting hypothalamo-pituitary gonadal axis in females and males of different species.

P. Froment, J. Dupont, A. Rak, 2017, Reproduction.

Peroxisome proliferator-activated receptors in reproductive tissues: from gametogenesis to parturition.

P. Froment, J. Dupont, P. Monget, 2006, The Journal of endocrinology.

Assessment of the body development kinetic of broiler breeders by non-invasive imaging tools.

P. Froment, C. Staub, J. Dupont, 2019, Poultry science.

Expression and Regulation of the SCD2 Desaturase in the Rat Ovary

P. Froment, J. Dupont, L. Tosca, 2006, Biology of reproduction.

Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS)

P. Froment, P. Touraine, 2006, PPAR research.

Effect of different levels of feed restriction and fish oil fatty acid supplementation on fat deposition by using different techniques, plasma levels and mRNA expression of several adipokines in broiler breeder hens

P. Froment, C. Staub, J. Dupont, 2018, PloS one.

Vaspin, a novel adipokine in woman granulosa cells physiology and PCOS pathogenesis?

P. Froment, J. Dupont, C. Ramé, 2021, The Journal of endocrinology.

Involvement of Chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells.

P. Froment, J. Dupont, C. Ramé, 2021, Reproduction.

Timing associated with oviductal sperm storage and release after artificial insemination in domestic hens.

P. Froment, T. Birkhead, J. Brillard, 2015, Theriogenology.

[mTORC1 and sirolimus: a link with fertility].

P. Froment, P. Tartarin, 2013, Medecine sciences : M/S.

Metformin Decreases GnRH- and Activin-Induced Gonadotropin Secretion in Rat Pituitary Cells: Potential Involvement of Adenosine 5′ Monophosphate-Activated Protein Kinase (PRKA)1

P. Froment, J. Dupont, L. Tosca, 2011, Biology of reproduction.

Triazole pesticides exposure impaired steroidogenesis associated to an increase in AHR and CAR expression in testis and altered sperm parameters in chicken.

P. Froment, J. Dupont, C. Ramé, 2023, Toxicology reports.

Concentration of Polycyclic Aromatic Hydrocarbons (PAHs) in Human Serum and Adipose Tissues and Stimulatory Effect of Naphthalene in Adipogenesis in 3T3-L1 Cells

P. Froment, J. Dupont, C. Ramé, 2023, International journal of molecular sciences.

Ileal interposition surgery targets the hepatic TGF‐β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD‐T2DM rat model of diabetes

P. Froment, C. Giulivi, P. Havel, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adipokines expression profile in liver, adipose tissue and muscle during chicken embryo development.

P. Froment, J. Dupont, C. Ramé, 2018, General and comparative endocrinology.

Activation of innate immune system in response to lipopolysaccharide in chicken Sertoli cells.

P. Froment, G. Michailidis, M. Anastasiadou, 2014, Reproduction.

Effects of mono-(2-ethylhexyl) phthalate (MEHP) on chicken germ cells cultured in vitro

J. Antignac, R. Cariou, P. Froment, 2013, Environmental Science and Pollution Research.

Central Role of 5′-AMP-Activated Protein Kinase in Chicken Sperm Functions1

P. Froment, Thi Mong Diep Nguyen, S. Métayer-Coustard, 2014, Biology of reproduction.

Microbiota Changes Due to Grape Seed Extract Diet Improved Intestinal Homeostasis and Decreased Fatness in Parental Broiler Hens

P. Froment, C. Staub, C. Philippe, 2020, Microorganisms.

Chronic dietary exposure to a glyphosate-based herbicide in broiler hens has long-term impacts on the progeny metabolism

P. Froment, J. Dupont, C. Ramé, 2023, Poultry science.

[Role of the fatty acids in ovarian functions: involvement of peroxisome proliferator-activated receptors (PPAR) and adipokines].

P. Froment, J. Dupont, C. Ramé, 2008, Gynecologie, obstetrique & fertilite.

Expression and effect of resistin on bovine and rat granulosa cell steroidogenesis and proliferation.

P. Froment, J. Dupont, C. Ramé, 2011, Reproduction.

Involvement of adipokines, AMPK, PI3K and the PPAR signaling pathways in ovarian follicle development and cancer.

P. Froment, J. Dupont, C. Ramé, 2012, The International journal of developmental biology.

Nutritional signals and reproduction

P. Froment, J. Dupont, M. Bertoldo, 2014, Molecular and Cellular Endocrinology.

Glyphosate presence in human sperm: First report and positive correlation with oxidative stress in an infertile French population.

P. Froment, C. Ramé, S. El Balkhi, 2024, Ecotoxicology and environmental safety.

Reproductive Abnormalities in Human IGF Binding Protein-1 Transgenic Female Mice.

P. Froment, P. Monget, D. Monniaux, 2002, Endocrinology.

The epoxiconazole and tebuconazole fungicides impair granulosa cells functions partly through the aryl hydrocarbon receptor (AHR) signalling with contrasted effects in obese, normo-weight and polycystic ovarian syndrome (PCOS) patients

P. Froment, C. Ramé, C. Jolivet, 2023, Toxicology reports.

Oral supplementation with Scabiosa artropurperea L. aqueous extract improves the in vivo sexual behaviour, sperm quality and androgen level in rams.

P. Froment, C. Ramé, Hnia Chograni, 2024, Reproduction in domestic animals = Zuchthygiene.

The hepatokine FGF21 stopped lipogenesis and reduced testosterone production in mLTC-1 Leydig Cell Line

P. Froment, C. Ramé, C. Chevaleyre, 2024, Molecular and Cellular Endocrinology.