D. Bax

发表

Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediatric Diffuse Intrinsic Pontine Gliomas

P. Varlet, S. Puget, C. Philippe, 2012, PloS one.

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease.

Richard G Grundy, James Lowe, Amar Gajjar, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cancer esearch apeutics , Targets , and Chemical Biology MT-Independent Temozolomide Resistance in Pediatric blastoma Cells Associated with a PI 3-Kinase – Mediated R / Stem Cell Gene Signature

D. Bax, G. Vassal, Chris Jones, 2010 .

/ Stem Cell Gene Signature HOX Mediated − Glioblastoma Cells Associated with a PI 3-Kinase MGMT-Independent Temozolomide Resistance in Pediatric

D. Bax, G. Vassal, Chris Jones, 2010 .

with a proapoptotic Bax to Bcl-2 ratio associated neoplasia in Barrett's oesophagus and is MUC4 is increased in high grade intraepithelial

P. Siersema, D. Bax, J. Haringsma, 2006 .

MUC4 is increased in high grade intraepithelial neoplasia in Barrett’s oesophagus and is associated with a proapoptotic Bax to Bcl-2 ratio

P. Siersema, D. Bax, H. van Dekken, 2004, Journal of Clinical Pathology.

Upregulation of MYCN Histone H 3 . 3 Mutations Drive Pediatric Glioblastoma through

A. Ashworth, R. Reis, D. Bax, 2013 .

Molecular alterations during development of esophageal adenocarcinoma

E. Kuipers, P. Siersema, D. Bax, 2005, Journal of surgical oncology.

Role of the rdxA and frxA genes in oxygen-dependent metronidazole resistance of Helicobacter pylori.

E. Kuipers, D. Bax, A. H. V. van Vliet, 2004, Journal of medical microbiology.

Barrett’s Esophagus: a Molecular Characterization

D. Bax, 2005 .

New GJA8 variants and phenotypes highlight its critical role in a broad spectrum of eye anomalies

R. Holt, P. Calvas, N. Chassaing, 2018, Human Genetics.

Does CDX2 expression predict Barrett's metaplasia in oesophageal columnar epithelium without goblet cells?

P. Siersema, D. Bax, H. van Dekken, 2006, Alimentary pharmacology & therapeutics.

of Barrett's oesophagus The homeodomain protein CDX2 is an early marker

D. Bax, J. Haringsma, L. Moons, 2006 .

The homeodomain protein CDX2 is an early marker of Barrett’s oesophagus

E. Kuipers, P. Siersema, D. Bax, 2004, Journal of Clinical Pathology.

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

Barbara S. Paugh, Chunxu Qu, R. Reis, 2013, Cancer research.

NovelOncogenicPDGFRAMutationsinPediatricHigh-Grade Gliomas

Barbara S. Paugh, Chunxu Qu, R. Reis, 2013 .

Molecular and Cellular Pathobiology NovelOncogenic PDGFRA Mutations inPediatricHighGrade inPediatricHighGrade inPediatricHighGrade Gliomas

Barbara S. Paugh, Chunxu Qu, R. Reis, 2013 .

Molecular and Cellular Pathobiology NovelOncogenic PDGFRA Mutations inPediatricHigh-Grade Gliomas

Barbara S. Paugh, Chunxu Qu, R. Reis, 2013 .

High-Grade Gliomas

C. Q. Lee, David T. W. Jones, Michael D. Brooks, 2012, Oxford Medicine Online.

Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity.

S. Al-Sarraj, D. Bax, Chris Jones, 2012, Cancer research.

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

A. Ashworth, R. Reis, D. Bax, 2013, Cancer discovery.

A Distinct Spectrum of Copy Number Aberrations in Pediatric High-Grade Gliomas

A. Ashworth, S. Al-Sarraj, A. Grigoriadis, 2010, Clinical Cancer Research.

Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development

Paul Workman, Darren Hargrave, Chris Jones, 2009, PloS one.

Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene Inactivation

S. Al-Sarraj, R. Reis, D. Bax, 2011, PloS one.

High-grade dysplasia in Barrett's esophagus is associated with increased expression of calgranulin A and B

E. Kuipers, P. Siersema, D. Bax, 2007, Scandinavian journal of gastroenterology.

Multifaceted Dysregulation of the Epidermal Growth Factor Receptor Pathway in Clear Cell Sarcoma of the Kidney

J. Reis-Filho, D. Bax, Chris Jones, 2007, Clinical Cancer Research.

De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies

Stephen W. Wilson, R. Holt, E. van Binsbergen, 2019, American journal of human genetics.

MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature.

R. Reis, D. Bax, G. Vassal, 2010, Cancer research.

EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

Paul Workman, Jorge S. Reis-Filho, Darren Hargrave, 2009, Clinical Cancer Research.

CDX2 Expression in Columnar Metaplasia of the Remnant Esophagus in Patients Who Underwent Esophagectomy

E. Kuipers, P. Siersema, D. Bax, 2007, Journal of clinical gastroenterology.

New GJA8 variants and phenotypes highlight its critical role in a broad spectrum of eye anomalies

Luciana Rodrigues da Silva, R. Holt, P. Calvas, 2018, Human Genetics.

Expanding the phenotype of the X-linked BCOR microphthalmia syndromes

P. Calvas, N. Chassaing, D. Bax, 2018, Human Genetics.

Expanding the phenotype of the X-linked BCOR microphthalmia syndromes

W. Newman, P. Calvas, N. Chassaing, 2018, Human Genetics.

New variant and expression studies provide further insight into the genotype-phenotype correlation in YAP1-related developmental eye disorders

R. Holt, D. Gerrelli, D. Bax, 2017, Scientific Reports.

Analysis of Fibroblast Growth Factor 14 (FGF14) structural variants reveals the genetic basis of the early onset nystagmus locus NYS4 and variable ataxia

D. Bax, M. Dunn, N. Ragge, 2022, European Journal of Human Genetics.

Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

J. Reis-Filho, S. Al-Sarraj, R. Reis, 2009 .

Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma

I. Huijbers, C. Isacke, D. Bax, 2008, Modern Pathology.

c-KIT overexpression, without gene amplification and mutation, in paediatric renal tumours

J. Reis-Filho, D. Bax, Chris Jones, 2007, Journal of Clinical Pathology.

H3F3A MUTATIONS IN PAEDIATRIC GLIOBLASTOMA REGULATE A SELF-RENEWAL GENE SIGNATURE

Paul Workman, Rui L. Reis, Darren Hargrave, 2012 .

Identification and functional characterisation of genetic variants in OLFM2 in children with developmental eye disorders

R. Holt, D. Gerrelli, D. Bax, 2016, Human Genetics.

Individuals with heterozygous variants in the Wnt-signalling pathway gene FZD5 delineate a phenotype characterized by isolated coloboma and variable expressivity

R. Holt, J. Clayton-Smith, P. Calvas, 2022, Ophthalmic genetics.

New variant and expression studies provide further insight into the genotype-phenotype correlation in YAP1-related developmental eye disorders

R. Holt, D. Gerrelli, D. Bax, 2017, Scientific Reports.

A DISTINCT SPECTRUM OF COPY NUMBER ABERRATIONS IN FORMALIN-FIXED, PARAFFIN-EMBEDDED PAEDIATRIC HIGH GRADE GLIOMA

Alan Mackay, Anita Grigoriadis, Chris Jones, 2010 .

Abstract 2962: Histone H3.3 mutations drive paediatric glioblastoma through upregulation of MYCN.

A. Ashworth, D. Bax, Chris Jones, 2013 .

Clinical, genetic and biochemical signatures of RBP4-related ocular malformations

R. Holt, N. Chassaing, D. Bax, 2023, Journal of Medical Genetics.

Clinical and genetic analysis further delineates the phenotypic spectrum of ALDH1A3-related anophthalmia and microphthalmia

P. Calvas, N. Chassaing, D. Bax, 2023, European Journal of Human Genetics.

High grade gliomas

C. Q. Lee, David T. W. Jones, Michael D. Brooks, 2022, Progress in Brain Research.

Identification and functional characterisation of genetic variants in OLFM2 in children with developmental eye disorders

R. Holt, D. Gerrelli, D. Bax, 2016, Human Genetics.

Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity.

S. Al-Sarraj, D. Bax, Suzanne E. Little, 2012, Cancer research.

A DISTINCT SPECTRUM OF COPY NUMBER ABERRATIONS IN PAEDIATRIC HIGH GRADE GLIOMAS

A. Grigoriadis, D. Bax, D. Hargrave, 2012 .

EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

J. Reis-Filho, S. Al-Sarraj, R. Reis, 2009, Clinical Cancer Research.