J. Grill

J. Grill, J. Habrand, K. Beccaria, 2016, Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology.

The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro.

W. Vandertop, M. Lamfers, J. Grill, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Conformal radiotherapy, reduced boost volume, hyperfractionated radiotherapy, and online quality control in standard-risk medulloblastoma without chemotherapy: results of the French M-SFOP 98 protocol.

J. Grill, P. Maingon, J. Habrand, 2003, International journal of radiation oncology, biology, physics.

The genomic landscape of dysembryoplastic neuroepithelial tumours and a comprehensive analysis of recurrent cases

David C. Jones, R. Beroukhim, P. Varlet, 2022, Neuropathology and applied neurobiology.

DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition

T. Jacques, J. Choudhary, Sara Temelso, 2020, Cancer discovery.

Disseminated diffuse midline gliomas, H3K27-altered mimicking diffuse leptomeningeal glioneuronal tumors: a diagnostical challenge!

P. Varlet, N. Boddaert, S. Puget, 2022, Acta neuropathologica communications.

Recurrent activating ACVR1/ALK2 mutations in diffuse intrinsic pontine glioma

M. Monje, Y. Butterfield, J. Mora, 2014 .

Constitutional mismatch repair deficiency–associated brain tumors: report from the European C4CMMRD consortium

P. Varlet, F. Andreiuolo, L. Guerrini-Rousseau, 2018, Neuro-oncology advances.

Parental stress and paediatric acquired brain injury

J. Grill, G. Dellatolas, C. Dufour, 2018, Brain injury.

Utility of Cerebrospinal Fluid Cytology in Newly Diagnosed Childhood Ependymoma

I. Pollack, J. Grill, J. Finlay, 2010, Journal of pediatric hematology/oncology.

Metastatic ependymoma: A multi‐institutional retrospective analysis of prognostic factors

I. Pollack, J. Grill, J. Finlay, 2008, Pediatric blood & cancer.

Childhood Ependymoma

J. Grill, C. Pascal, Kalifa Chantal, 2020, Paediatric drugs.

Efficient and Selective Gene Transfer into Primary Human Brain Tumors by Using Single-Chain Antibody-Targeted Adenoviral Vectors with Native Tropism Abolished

M. Lamfers, J. Grill, H. Haisma, 2002, Journal of Virology.

Craniopharyngioma: the pendulum of surgical management

N. Boddaert, S. Puget, C. Sainte-Rose, 2005, Child's Nervous System.

Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.

W. Vandertop, M. Lamfers, B. Geoerger, 2002, Cancer research.

Oncolytic Virotherapy of Meningiomas in Vitro with Replication-competent Adenovirus

W. Vandertop, M. Lamfers, P. Sminia, 2005, Neurosurgery.

EXPERIMENTAL STUDIES

W. Vandertop, M. Lamfers, P. Sminia, 2004 .

The pediatric supratentorial MYCN-amplified high-grade gliomas methylation class presents the same radiological, histopathological and molecular features as their pontine counterparts

P. Varlet, N. Boddaert, S. Puget, 2020, Acta Neuropathologica Communications.

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours

P. Varlet, Chris Jones, J. Grill, 2017, Acta Neuropathologica Communications.

Relapses of optic pathway tumors after first‐line chemotherapy

C. Sainte-Rose, J. Grill, J. Habrand, 2009, Pediatric blood & cancer.

Oncolytic Activity of the E 1 B-55 kDa-deleted Adenovirus ONYX-015 Is Independent of Cellular p 53 Status in Human Malignant Glioma Xenografts 1

P. Opolon, B. Geoerger, G. Vassal, 2002 .

High-grade glioma in children under 5 years of age: a chemotherapy only approach with the BBSFOP protocol.

D. Frappaz, S. Puget, J. Grill, 2006, European journal of cancer.

Chemotherapy for unresectable and recurrent intramedullary glial tumours in children

J. Grill, M. Zérah, A. Lellouch‐Tubiana, 1999, British Journal of Cancer.

Posterior fossa ependymoma H3 K27-mutant: an integrated radiological and histomolecular tumor analysis

P. Varlet, N. Boddaert, S. Puget, 2022, Acta Neuropathologica Communications.

Childhood craniopharyngioma: hypothalamus-sparing surgery decreases the risk of obesity.

M. Polak, K. Busiah, N. Boddaert, 2013, The Journal of clinical endocrinology and metabolism.

Pediatric spinal pilocytic astrocytomas form a distinct epigenetic subclass from pilocytic astrocytomas of other locations and diffuse leptomeningeal glioneuronal tumours

P. Varlet, N. Boddaert, D. Figarella-Branger, 2022, Acta Neuropathologica.

NF1-like optic pathway gliomas in children: clinical and molecular characterization of this specific presentation

P. Varlet, L. Guerrini-Rousseau, J. Grill, 2019, Neuro-oncology advances.

MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.

P. Morgan, P. Varlet, G. Vassal, 2022, Radiology.

EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression

P. Varlet, F. Andreiuolo, J. Grill, 2020, Acta Neuropathologica Communications.

High-dose busulfan and thiotepa followed by autologous stem cell transplantation (ASCT) in previously irradiated medulloblastoma patients: high toxicity and lack of efficacy

J. Grill, J. Habrand, D. Valteau‐Couanet, 2005, Bone Marrow Transplantation.

Pharmacodynamics of tandem high-dose melphalan with peripheral blood stem cell transplantation in children with neuroblastoma and medulloblastoma

G. Vassal, J. Grill, C. Hill, 2001, Bone Marrow Transplantation.

Phase I study of vinblastine in combination with nilotinib in children, adolescents, and young adults with refractory or recurrent low-grade glioma

A. Paci, G. Le Teuff, B. Geoerger, 2020, Neuro-oncology advances.

A high-dose busulfan-thiotepa combination followed by autologous bone marrow transplantation in childhood recurrent ependymoma. A phase-II study.

C. Sainte-Rose, J. Grill, M. Terrier-Lacombe, 1996, Pediatric neurosurgery.

J. Grill, C. Dufour, M. Jullien, 2008, Journal of pediatric hematology/oncology.

EPEN-02. OPTIMISING BIOMARKERS FOR ACCURATE EPENDYMOMA DIAGNOSIS, PROGNOSTICATION AND STRATIFICATION WITHIN INTERNATIONAL CLINICAL TRIALS: A BIOMECA STUDY

S. Pfister, P. Varlet, T. Jacques, 2022, medRxiv.

Re-irradiation of recurrent pediatric ependymoma: modalities and outcomes: a twenty-year survey

S. Puget, J. Grill, P. Bondiau, 2016, SpringerPlus.

Pediatric low-grade gliomas: how modern biology reshapes the clinical field.

R. Beroukhim, K. Ligon, J. Grill, 2014, Biochimica et biophysica acta.

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

David T. W. Jones, P. Raman, S. Pfister, 2018, Cancer cell.

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

Kun Mu, Stefan M. Pfister, Sergey Popov, 2017, Cancer cell.

Intracerebral small round cell tumor: An unusual case with EWS‐WT1 translocation

P. Varlet, O. Delattre, J. Grill, 2008, Pediatric blood & cancer.

Stereotactic biopsy of diffuse pontine lesions in children.

N. Boddaert, S. Puget, T. Roujeau, 2007, Journal of neurosurgery.

Stability of Etoposide Solutions in Disposable Infusion Devices for Day Hospital Cancer Practices

A. Paci, J. Grill, L. Mercier, 2014, Drugs in R&D.

Germline SUFU mutation carriers and medulloblastoma: clinical characteristics, cancer risk, and prognosis

P. Varlet, O. Delattre, S. Puget, 2018, Neuro-oncology.

High frequency of germline SUFU mutations in children with desmoplastic/nodular medulloblastoma younger than 3 years of age.

P. Varlet, O. Delattre, S. Puget, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations

P. Varlet, O. Delattre, J. Grill, 2009, Journal of Medical Genetics.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Roland Eils, Pieter Wesseling, Martin Sill, 2016, Cell.

Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Ranadip Pal, Charles Keller, Nathalene Truffaux, 2015, Nature Medicine.

Cognitive Profile of Children With Intracranial Germ Cell Tumor According to Tumor Location

L. Guerrini-Rousseau, J. Grill, G. Dellatolas, 2018, Journal of pediatric hematology/oncology.

Central nervous system germ cell tumors: an update

L. Guerrini-Rousseau, J. Grill, C. Dufour, 2014, Current opinion in oncology.

Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis.

D. Figarella-Branger, D. Ellison, J. Grill, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Water and Electrolyte Disorders at Long-Term Post-Treatment Follow-Up in Paediatric Patients with Suprasellar Tumours Include Unexpected Persistent Cerebral Salt-Wasting Syndrome

M. Polak, S. Puget, L. Guerrini-Rousseau, 2014, Hormone Research in Paediatrics.

Thalamic tumors in children: a reappraisal.

N. Boddaert, S. Puget, T. Roujeau, 2007, Journal of neurosurgery.

Affections pseudotumorales : dix ans d'expérience dans un service d'oncologie pédiatriquePseudotumoral diseases: ten years experience in a department of pediatric oncology

J. Grill, L. Brugières, D. Valteau‐Couanet, 2002 .

Childhood supratentorial ependymomas with YAP1‐MAMLD1 fusion: an entity with characteristic clinical, radiological, cytogenetic and histopathological features

C. Sommer, P. Varlet, T. Acker, 2018, Brain pathology.

Modeling the Interaction between the Microenvironment and Tumor Cells in Brain Tumors

F. Ginhoux, M. Bruschi, J. Grill, 2020, Neuron.

Neuro-oncology: Stability of medulloblastoma subgroups at tumour recurrence

J. Grill, C. Dufour, 2014, Nature Reviews Neurology.

Clinical Relevance of Tumor Cells with Stem-Like Properties in Pediatric Brain Tumors

C. Daumas-Duport, P. Varlet, I. Bièche, 2011, PloS one.

Neuronal differentiation distinguishes supratentorial and infratentorial childhood ependymomas.

Pascale Varlet, Nathalie Boddaert, Cathy Philippe, 2010, Neuro-oncology.

Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

P. Varlet, I. Bièche, A. Kauffmann, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts.

P. Opolon, B. Geoerger, G. Vassal, 2002, Cancer research.

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.

David T. W. Jones, G. Reifenberger, S. Pfister, 2020, Neuro-oncology.

Cancer Cell Integrated molecular meta-analysis of 1000 paediatric high grade and diffuse intrinsic pontine glioma

R. Verhaak, M. Monje, J. Mora, 2017 .

Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

Roland Eils, Thomas Zichner, Hans Lehrach, 2016, Nature Medicine.

Vemurafenib in pediatric patients with BRAFV600E mutated high‐grade gliomas

P. Varlet, A. Paci, B. Geoerger, 2014, Pediatric blood & cancer.

Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma

S. Al-Sarraj, Sara Temelso, J. Grill, 2021, Cancer discovery.

Copy-number alterations reshape the classification of diffuse intrinsic pontine gliomas. First exome sequencing results of the BIOMEDE trial.

K. Blomgren, P. Varlet, S. Puget, 2021, medRxiv.

New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis.

S. Mériaux, P. Varlet, F. Geffroy, 2017, Oncotarget.

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

P. Varlet, N. Boddaert, S. Puget, 2015, Acta Neuropathologica.

Beta‐catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

Emmanuel Barillot, Christine Haberler, Pascale Varlet, 2009, The Journal of pathology.

Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location

David T. W. Jones, S. Pfister, P. Varlet, 2018, Acta Neuropathologica Communications.

An integrative radiological, histopathological and molecular analysis of pediatric pontine histone-wildtype glioma with MYCN amplification (HGG-MYCN)

K. Blomgren, P. Varlet, N. Boddaert, 2019, Acta Neuropathologica Communications.

The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease

Adam Lane, Darren Hargrave, Chris Jones, 2017, Journal of Neuro-Oncology.

Biopsy in a series of 130 pediatric diffuse intrinsic Pontine gliomas

P. Varlet, S. Puget, T. Roujeau, 2015, Child's Nervous System.

Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma

L. Macconaill, S. Puget, C. Philippe, 2012, Pediatric blood & cancer.

International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma

M. Monje, C. Hawkins, Chris Jones, 2018, Journal of Neuro-Oncology.

Diffuse intrinsic pontine gliomas—current management and new biologic insights. Is there a glimmer of hope?

J. Grill, N. Jabado, K. Cohen, 2017, Neuro-oncology.

New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis

S. Mériaux, P. Varlet, F. Geffroy, 2017, Oncotarget.

TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG)

P. Varlet, N. Boddaert, S. Puget, 2019, Clinical Cancer Research.

Inhibition of the NOTCH pathway using γ-secretase inhibitor RO4929097 has limited antitumor activity in established glial tumors.

S. Puget, B. Geoerger, G. Vassal, 2015, Anti-cancer drugs.

Prognostic classification of pediatric medulloblastoma based on chromosome 17p loss, expression of MYCC and MYCN, and Wnt pathway activation.

O. Delattre, W. Park, S. Puget, 2012, Neuro-oncology.

Co‐occurrence of histone H3 K27M and BRAF V600E mutations in paediatric midline grade I ganglioglioma

P. Varlet, N. Boddaert, D. Figarella-Branger, 2018, Brain pathology.

Long survival in a child with a mutated K27M-H3.3 pilocytic astrocytoma

J. Grill, C. Maurage, F. Escande, 2015, Annals of clinical and translational neurology.

Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts

Richard G Grundy, Jacques Grill, Mehmet Kocak, 2011, Journal of Negative Results in BioMedicine.

Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging

M. Kool, S. Pfister, P. Varlet, 2018, Brain pathology.

Pediatric high-grade glioma MYCN is frequently associated with Li-Fraumeni syndrome

P. Varlet, L. Guerrini-Rousseau, J. Grill, 2023, Acta Neuropathologica Communications.

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

S. Khatua, S. Pfister, P. Varlet, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

High-grade gliomas in adolescents and young adults highlight histomolecular differences with their adult and paediatric counterparts.

E. Mandonnet, M. Sanson, P. Varlet, 2020, Neuro-oncology.

MYB-QKI rearrangements in Angiocentric Glioma drive tumorigenicity through a tripartite mechanism

Liliana Goumnerova, Caterina Giannini, Rameen Beroukhim, 2016, Nature Genetics.

Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma

P. Varlet, S. Puget, T. Roujeau, 2011, Journal of Neuro-Oncology.

Primary gliomatosis cerebri involving gray matter in pediatrics: a distinct entity? A multicenter study of 14 cases

N. André, L. Riffaud, D. Frappaz, 2013, Child's Nervous System.

Neuropathological and Neuroradiological Spectrum of Pediatric Malignant Gliomas: Correlation With Outcome

P. Varlet, N. Boddaert, S. Puget, 2011, Neurosurgery.

Clinical, Imaging, Histopathological and Molecular Characterization of Anaplastic Ganglioglioma

B. Devaux, E. Dezamis, P. Varlet, 2016, Journal of neuropathology and experimental neurology.

Posterior Fossa Gangliogliomas

P. Varlet, N. Boddaert, S. Puget, 2015 .

Delays in diagnosis of paediatric cancers: a systematic review and comparison with expert testimony in lawsuits.

J. Grill, R. Amalberti, M. Chalumeau, 2012, The Lancet. Oncology.

Is biopsy safe in children with newly diagnosed diffuse intrinsic pontine glioma?

S. Puget, J. Grill, T. Blauwblomme, 2012, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.

S. Puget, C. Philippe, F. Andreiuolo, 2015, Neuro-oncology.

Medulloblastoma: what is the role of molecular genetics?

J. Grill, C. Dufour, N. Entz-Werlé, 2008, Expert review of anticancer therapy.

Comparative genomic hybridization detects specific cytogenetic abnormalities in pediatric ependymomas and choroid plexus papillomas.

C. Sainte-Rose, G. Vassal, J. Grill, 2002, Cancer genetics and cytogenetics.

A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study

D. Frappaz, B. Geoerger, J. Grill, 2013, Journal of Neuro-Oncology.

Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma.

J. Grill, F. de Fraipont, M. Favrot, 2006, Cancer genetics and cytogenetics.

Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma.

P. Morgan, P. Varlet, G. Vassal, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile

E. Dezamis, P. Varlet, N. Boddaert, 2022, Acta neuropathologica communications.

Patients in Pediatric Phase I and Early Phase II Clinical Oncology Trials at Gustave Roussy: A 13-Year Center Experience

B. Geoerger, G. Vassal, J. Grill, 2015, Journal of pediatric hematology/oncology.

Role of neoadjuvant chemotherapy in metastatic medulloblastoma: a comparative study in 92 children

P. Varlet, S. Puget, F. Andreiuolo, 2020, Neuro-oncology.

Radiological Evaluation of Newly Diagnosed Non-Brainstem Pediatric High-Grade Glioma in the HERBY Phase II Trial

P. Morgan, P. Varlet, G. Vassal, 2020, Clinical Cancer Research.

The dark matter of diffuse intrinsic pontine gliomas: an update

P. Varlet, S. Puget, J. Grill, 2019, Expert Opinion on Orphan Drugs.

Phase II study of irinotecan in combination with temozolomide (TEMIRI) in children with recurrent or refractory medulloblastoma: a joint ITCC and SIOPE brain tumor study.

B. Geoerger, J. Grill, D. Hargrave, 2013, Neuro-oncology.

WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial

P. Varlet, T. Jacques, D. Figarella-Branger, 2019, Neuro-oncology.

Rubinstein–Taybi syndrome predisposing to non‐WNT, non‐SHH, group 3 medulloblastoma

O. Delattre, F. Radvanyi, J. Grill, 2014, Pediatric blood & cancer.

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

P. Morgan, Sara Temelso, G. Vassal, 2021, Neuro-oncology advances.

Injuries to inferior vermis and dentate nuclei predict poor neurological and neuropsychological outcome in children with malignant posterior fossa tumors

N. Boddaert, S. Puget, C. Sainte-Rose, 2009, Cancer.

High‐dose chemotherapy with autologous stem cell rescue followed by posterior fossa irradiation for local medulloblastoma recurrence or progression after conventional chemotherapy

D. Frappaz, C. Sainte-Rose, J. Grill, 2007, Cancer.

A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood ( 16 years ) low grade glioma e A final report

K. Skullerud, T. Egeland, D. Machin, 2017 .

Gene therapy for meningioma: improved gene delivery with targeted adenoviruses.

W. Vandertop, M. Lamfers, J. Grill, 2002, Journal of neurosurgery.

Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion

P. Varlet, N. Boddaert, S. Puget, 2015, Acta Neuropathologica Communications.

Progression-free survival in children with optic pathway tumors: dependence on age and the quality of the response to chemotherapy--results of the first French prospective study for the French Society of Pediatric Oncology.

D. Frappaz, J. Grill, E. Sariban, 2003, Journal of Clinical Oncology.

Prognostic factors of CNS tumours in Neurofibromatosis 1 (NF1): a retrospective study of 104 patients.

Jacques Grill, François Doz, Pierre Wolkenstein, 2003, Brain : a journal of neurology.

Clinicopathologic prognostic factors in childhood atypical teratoid and rhabdoid tumor of the central nervous system

N. André, P. Varlet, D. Frappaz, 2012, Cancer.

Can Structural MRI Radiomics Predict DIPG Histone H3 Mutation and Patient Overall Survival at Diagnosis Time?

Vincent Frouin, Frédérique Frouin, Irène Buvat, 2019, 2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI).

Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion

P. Varlet, N. Boddaert, S. Puget, 2015, Acta neuropathologica communications.

Neuropsychological outcome in children with optic pathway tumours when first-line treatment is chemotherapy

A. Streri, E. Gentaz, C. Lorenzi, 2003, British Journal of Cancer.

EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY

Tina N. Davis, Forrest M Kievit, Atique U. Ahmed, 2013 .

Interval between onset of symptoms and diagnosis of medulloblastoma in children: distribution and determinants in a population-based study

S. Puget, C. Sainte-Rose, J. Grill, 2011, European Journal of Pediatrics.

Pediatric ependymomas: will molecular biology change patient management?

J. Grill, C. Ferreira, G. Bergthold, 2011, Current opinion in oncology.

Postoperative chemotherapy without irradiation for ependymoma in children under 5 years of age: a multicenter trial of the French Society of Pediatric Oncology.

D. Frappaz, J. Grill, J. Habrand, 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

What have we learnt from previous phase II trials to help in the management of childhood brain tumours?

J. Grill, E. Bouffet, P. Chastagner, 2001, European journal of cancer.

Pediatric brain tumors as a developmental disease

L. Guerrini-Rousseau, J. Grill, Marco Bruschi, 2021, Current opinion in oncology.

Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma

J. Grill, D. Curiel, H. Haisma, 2002, The journal of gene medicine.

The EP300:BCOR fusion extends the genetic alteration spectrum defining the new tumoral entity of “CNS tumors with BCOR internal tandem duplication”

P. Varlet, N. Boddaert, J. Grill, 2020, Acta neuropathologica communications.

The pediatric supratentorial MYCN-amplified high-grade gliomas methylation class presents the same radiological, histopathological and molecular features as their pontine counterparts

P. Varlet, N. Boddaert, S. Puget, 2020, Acta Neuropathologica Communications.

The EP300:BCOR fusion extends the genetic alteration spectrum defining the new tumoral entity of “CNS tumors with BCOR internal tandem duplication”

P. Varlet, N. Boddaert, J. Grill, 2020, Acta Neuropathologica Communications.

Arterial Spin Labeling to Predict Brain Tumor Grading in Children: Correlations between Histopathologic Vascular Density and Perfusion MR Imaging.

P. Varlet, N. Boddaert, F. Brunelle, 2016, Radiology.

CNS tumors with YWHAE:NUTM2 and KDM2B-fusions present molecular similarities to extra-CNS tumors having BCOR internal tandem duplication or alternative fusions

P. Varlet, N. Boddaert, S. Puget, 2021, Acta neuropathologica communications.

Pediatric methylation class HGNET-MN1: unresolved issues with terminology and grading

P. Varlet, N. Boddaert, S. Puget, 2019, Acta Neuropathologica Communications.

Metastatic Medulloblastoma in Childhood: Chang's Classification Revisited

J. Grill, A. Laplanche, C. Dufour, 2011, International journal of surgical oncology.

Do medulloblastoma tumors meet the food and drug administration criteria for anti‐erbB2 therapy with trastuzumab?

M. Mathieu, B. Geoerger, G. Vassal, 2008, Pediatric blood & cancer.

Deciphering the genetic and epigenetic landscape of pediatric bithalamic tumors

P. Varlet, N. Boddaert, S. Puget, 2021, Brain pathology.

Multimodal treatment of craniopharyngioma: defining a risk-adapted strategy.

S. Puget, C. Sainte-Rose, J. Grill, 2006, Journal of pediatric endocrinology & metabolism : JPEM.

Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review.

P. Varlet, J. Grill, A. Laquérriere, 2016, Neurosurgery.

Pediatric infratentorial gangliogliomas: a retrospective series.

N. Boddaert, S. Puget, T. Roujeau, 2007, Journal of neurosurgery.

Relationship between the brain radiation dose for the treatment of childhood cancer and the risk of long-term cerebrovascular mortality.

J. Grill, C. Rubino, F. de Vathaire, 2011, Brain : a journal of neurology.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Volker Hovestadt, Stefan M. Pfister, Brent A. Orr, 2016, Cell.

Pseudoprogression after high-dose busulfan-thiotepa with autologous stem cell transplantation and radiation therapy in children with brain tumors: Impact on survival.

J. Grill, J. Habrand, P. Blanchard, 2012, Neuro-oncology.

Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes.

C. Sainte-Rose, J. Grill, I. Jambaqué, 1999, International journal of radiation oncology, biology, physics.

[Pediatric ependymomas: Current diagnosis and therapy].

D. Frappaz, J. Grill, A. Vasiljevic, 2016, Bulletin du cancer.

Oncolytic Activity of p53-Expressing Conditionally Replicative Adenovirus AdΔ24-p53 against Human Malignant Glioma

G. Giaccone, P. Opolon, W. Vandertop, 2004, Cancer Research.

Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors

M. Lamfers, J. Grill, T. Würdinger, 2003, Gene Therapy.

Oncolytic adenoviruses for treatment of brain tumours

J. Grill, W. Gerritsen, W. Vandertop, 2002, Expert opinion on biological therapy.

The Therapy of Infantile Malignant Brain Tumors: Current Status?

Jacques Grill, J. Grill, Chantal Kalifa, 2005, Journal of Neuro-Oncology.

Prognostic Clinical and Biologic Features for Overall Survival after Relapse in Childhood Medulloblastoma

P. Varlet, S. Puget, L. Guerrini-Rousseau, 2020, Cancers.

High‐dose busulfan–thiotepa with autologous stem cell transplantation followed by posterior fossa irradiation in young children with classical or incompletely resected medulloblastoma

P. Varlet, C. Sainte-Rose, J. Grill, 2014, Pediatric blood & cancer.

Online quality control, hyperfractionated radiotherapy alone and reduced boost volume for standard risk medulloblastoma: long-term results of MSFOP 98.

D. Figarella-Branger, J. Grill, P. Maingon, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tandem high‐dose chemotherapy and autologous stem cell rescue in children with newly diagnosed high‐risk medulloblastoma or supratentorial primitive neuro‐ectodermic tumors

P. Varlet, S. Puget, J. Grill, 2014, Pediatric blood & cancer.

Object Detection Improves Tumour Segmentation in MR Images of Rare Brain Tumours

V. Frouin, N. Boddaert, C. Philippe, 2021, Cancers.

Teachers’ report of learning and behavioural difficulties in children treated for cerebellar tumours

J. Grill, G. Dellatolas, D. Viguier, 2012, Brain injury.

Quality‐of‐life, mood and executive functioning after childhood craniopharyngioma treated with surgery and proton beam therapy

S. Puget, J. Grill, J. Habrand, 2012, Brain injury.

Patterns of neuropsychological deficits in children with medulloblastoma according to craniospatial irradiation doses

J. Grill, I. Jambaqué, C. Bulteau, 2000, Developmental medicine and child neurology.

Current and evolving knowledge of prognostic factors for pediatric ependymomas.

S. Puget, F. Andreiuolo, J. Grill, 2013, Future oncology.

Preoperative chemotherapy in children with high-risk medulloblastomas: a feasibility study.

C. Sainte-Rose, J. Grill, D. Rénier, 2005, Journal of neurosurgery.

Appraisal of the current staging system for residual medulloblastoma by volumetric analysis

N. Boddaert, S. Puget, C. Sainte-Rose, 2011, Child's Nervous System.

Visual Agnosia After Treatment of a Posterior Fossa Ependymoma in a 16-Month-Old Girl

J. Grill, C. Bulteau, O. Hartmann, 2001, Journal of child neurology.

Neuropsychological consequences of childhood medulloblastoma and possible interventions: A review.

L. Hertz-Pannier, J. Grill, M. Noulhiane, 2018, Neuro-Chirurgie.

Impairment of intellectual functions after surgery and posterior fossa irradiation in children with ependymoma is related to age and neurologic complications

J. Grill, J. Habrand, G. Dellatolas, 2008, BMC Cancer.

Critical risk factors for intellectual impairment in children with posterior fossa tumors: the role of cerebellar damage.

C. Sainte-Rose, J. Grill, G. Dellatolas, 2004, Journal of neurosurgery.

NF2 and ZFTA evaluation in the diagnostic algorithm of pediatric posterior fossa ependymoma with H3K27ME3 retained expression

P. Varlet, N. Boddaert, S. Puget, 2023, Acta Neuropathologica Communications.

Cerebellar mutism: definitions, classification and grading of symptoms

J. Grill, K. Schmiegelow, A. Sehested, 2011, Child's Nervous System.

Cognitive and Academic Outcome After Benign or Malignant Cerebellar Tumor in Children

N. Boddaert, S. Puget, C. Sainte-Rose, 2009, Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.

Therapeutic schedules influence the pattern of intellectual decline after irradiation of posterior fossa tumors

J. Grill, J. Habrand, G. Dellatolas, 2005, Pediatric blood & cancer.

Elevated Plasma Ferritin and Busulfan Pharmacodynamics During High‐dose Chemotherapy Regimens in Children with Malignant Solid Tumors

A. L. Maître, A. Paci, G. Vassal, 2007, Clinical pharmacology and therapeutics.

Targeting of adenoviral vectors through a bispecific single-chain antibody

J. Grill, D. Curiel, H. Haisma, 2000, Cancer Gene Therapy.

Clinico-Radio-Histo-Molecular and Neurocognitive Characteristics of Diffuse Gliomas in Adolescent and Young Adults: A Comprehensive Review

P. Varlet, C. Oppenheim, N. Boddaert, 2023, Oncology.

A common polymorphism in the 5′ UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy

S. Puget, J. Grill, J. Kilday, 2015, Genes & development.

Evaluation of the Implementation of the Response Assessment in Neuro-Oncology Criteria in the HERBY Trial of Pediatric Patients with Newly Diagnosed High-Grade Gliomas

P. Morgan, G. Vassal, J. Grill, 2019, American Journal of Neuroradiology.

Response Assessment in Pediatric Neuro-Oncology: Implementation and Expansion of the RANO Criteria in a Randomized Phase II Trial of Pediatric Patients with Newly Diagnosed High-Grade Gliomas

P. Morgan, J. Grill, D. Hargrave, 2016, American Journal of Neuroradiology.

NF1 optic pathway glioma: analyzing risk factors for visual outcome and indications to treat

Jo-Fen Liu, D. Evans, J. Grill, 2020, Neuro-oncology.

Proton therapy in pediatric skull base and cervical canal low-grade bone malignancies.

C. Sainte-Rose, J. Grill, J. Habrand, 2008, International journal of radiation oncology, biology, physics.

High Prevalence of Developmental Venous Anomaly in Diffuse Intrinsic Pontine Gliomas: A Pediatric Control Study.

P. Varlet, N. Boddaert, S. Puget, 2019, Neurosurgery.

Epileptic seizures in anaplastic gangliogliomas

B. Devaux, G. Huberfeld, E. Dezamis, 2017, British journal of neurosurgery.

Radiation therapy in the management of craniopharyngioma: current concepts and future developments.

J. Grill, J. Habrand, F. Saran, 2006, Journal of pediatric endocrinology & metabolism : JPEM.

ddPCR-based detection of circulating tumour DNA from paediatric high grade and diffuse midline glioma patients

P. Morgan, Sara Temelso, G. Vassal, 2021 .

Assessment of executive functioning in children and young adults treated for frontal lobe tumours using ecologically valid tests

S. Puget, C. Sainte-Rose, J. Grill, 2016, Neuropsychological rehabilitation.

Impact of a pediatric posterior fossa tumor and its treatments on motor procedural learning.

J. Pariente, F. Tensaouti, J. Grill, 2023, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells

J. Grill, M. Debily, E. Oberlin, 2023, bioRxiv.

DIPG-35. BIOLOGICAL MEDICINE FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) ERADICATION: RESULTS OF THE THREE ARM BIOMARKER-DRIVEN RANDOMIZED BIOMEDE 1.0 TRIAL

K. Blomgren, P. Varlet, S. Puget, 2020, Neuro-Oncology.

EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression

P. Varlet, F. Andreiuolo, J. Grill, 2020, Acta neuropathologica communications.

Dactinomycin‐Induced, Severe Lichenoid Eruption in a Child

J. Grill, C. Patte, L. Galmiche, 2006, Pediatric dermatology.

Quality of survival and cognitive performance in children treated for medulloblastoma in the PNET 4 randomized controlled trial.

J. Grill, G. Dellatolas, A. Wiener, 2017, Neuro-oncology practice.

Pediatric methylation class HGNET-MN1: unresolved issues with terminology and grading

P. Varlet, N. Boddaert, S. Puget, 2019, Acta Neuropathologica Communications.

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours

P. Varlet, Chris Jones, J. Grill, 2017, Acta neuropathologica communications.

Neuropsychological Outcome of Children Treated for Standard Risk Medulloblastoma in the PNET4 European Randomized Controlled Trial of Hyperfractionated Versus Standard Radiation Therapy and Maintenance Chemotherapy.

J. Grill, G. Dellatolas, R. Kortmann, 2015, International journal of radiation oncology, biology, physics.

Questionnaire-based reports of Quality of Survival and direct assessments of cognitive performance in children treated for medulloblastoma in the PNET 4 randomized controlled trial

J. Grill, G. Dellatolas, R. Kortmann, 2017 .

Neuropsychological outcome of children treated for standard risk medulloblastoma in the PNET 4 European randomised controlled trial of hyperfractionated ( HFRT ) versus standard radiotherapy ( STRT ) and maintenance chemotherapy

J. Grill, G. Dellatolas, S. Rutkowski, 2015 .

Intellectual, educational, and situation-based social outcome in adult survivors of childhood medulloblastoma

S. Puget, J. Grill, G. Dellatolas, 2019, Developmental neurorehabilitation.

Low Bone Mineral Density and High Incidences of Fractures and Vitamin D Deficiency in 52 Pediatric Cancer Survivors

M. Polak, C. Sainte-Rose, J. Grill, 2010, Hormone Research in Paediatrics.

Histone H3 genotyping refines clinico-radiological diagnostic and prognostic criteria in DIPG

J. Grill, M. Debily, D. Castel, 2016, Acta Neuropathologica.

EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts

P. Opolon, B. Geoerger, G. Vassal, 2008, International journal of cancer.

High-dose chemotherapy in childhood brain tumours

G. Vassal, J. Grill, B. Pizer, 1999, Child's Nervous System.

Remediation of learning difficulties in children after treatment for a cerebellar medulloblastoma: A single-case study

J. Grill, G. Dellatolas, M. Zérah, 2008, Developmental neurorehabilitation.

Risk factors for obesity in adulthood among survivors of childhood cancer

J. Grill, P. Bondiau, A. Dumas, 2023, Obesity.

How can we differentiate supratentorial tumor recurrence from postradiation imaging changes in children treated for primary malignant brain tumors?

P. Varlet, H. Brisse, N. Boddaert, 2023, Journal of neurosurgery. Pediatrics.

Atypical teratoid rhabdoid tumor mimicking beta-catenin-positive nodular medulloblastoma

P. Varlet, N. Boddaert, S. Puget, 2011, Acta Neuropathologica.

Comprehensive Treatment strategy for Low Grade Glioma in children and adolescents including a randomized chemotherapy trial and a radiotherapy trial

J. Grill, G. Perilongo, J. Helgestad, 2008 .

High-dose chemotherapy in children with newly-diagnosed medulloblastoma.

J. Grill, C. Dufour, C. Kalifa, 2006, The Lancet. Oncology.

Multimodal MRI radiomic models to predict genomic mutations in diffuse intrinsic pontine glioma with missing imaging modalities

N. Boddaert, C. Philippe, J. Grill, 2023, Frontiers in Medicine.

In vivo antitumor activity of S16020, a topoisomerase II inhibitor, and doxorubicin against human brain tumor xenografts

Jacques Grill, Gilles Vassal, C. Sainte-Rose, 2003, Cancer Chemotherapy and Pharmacology.

Conceptions of time in children treated for malignant cerebellar tumours

J. Grill, G. Dellatolas, F. Labrell, 2014, Brain injury.

Sequential high-dose chemotherapy with autologous stem cell rescue for children with high-risk medulloblastoma and supratentorial primitive neuroectodermal tumours

J. Grill, C. Dufour, V. Minard-Colin, 2008 .

A CBF decrease in the left supplementary motor areas: New insight into postoperative pediatric cerebellar mutism syndrome using arterial spin labeling perfusion MRI

M. Zilbovicius, H. Lemaître, N. Boddaert, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Astrocytes Reverted to a Neural Progenitor‐like State with Transforming Growth Factor Alpha Are Sensitized to Cancerous Transformation

P. Varlet, M. Junier, P. Dessen, 2009, Stem cells.

A comprehensive analysis of infantile central nervous system tumors to improve distinctive criteria for infant‐type hemispheric glioma versus desmoplastic infantile ganglioglioma/astrocytoma

P. Varlet, N. Boddaert, S. Puget, 2023, Brain pathology.

Bevacizumab dosing strategy in paediatric cancer patients based on population pharmacokinetic analysis with external validation

J. Grill, J. Merks, N. Daw, 2015, British journal of clinical pharmacology.

Constitutional mismatch repair deficiency–associated brain tumors: report from the European C4CMMRD consortium

P. Varlet, F. Andreiuolo, L. Guerrini-Rousseau, 2019, Neuro-oncology advances.

An integrative radiological, histopathological and molecular analysis of pediatric pontine histone-wildtype glioma with MYCN amplification (HGG-MYCN)

K. Blomgren, P. Varlet, N. Boddaert, 2019, Acta Neuropathologica Communications.

Chemotherapy for unresectable and recurrent intramedullary glial tumours in children

J. Grill, M. Zérah, A. Lellouch‐Tubiana, 1999 .

K. Skullerud, T. Egeland, D. Machin, 2017, European journal of cancer.

Forniceal glioma in children. Clinical article.

P. Varlet, N. Boddaert, S. Puget, 2009, Journal of neurosurgery. Pediatrics.

The pontine diffuse midline glioma, EGFR-subtype with ependymal features: Yet another face of diffuse midline glioma, H3K27-altered.

P. Varlet, N. Boddaert, J. Grill, 2023, Brain pathology.

Is biopsy safe in children with newly diagnosed diffuse intrinsic pontine glioma

S. Puget, J. Grill, T. Blauwblomme, 2012 .

[Optic pathway gliomas in neurofibromatosis type I. Longitudinal study of 30 cases in two multidisciplinary practices].

C. Adamsbaum, J. Grill, I. Jambaqué, 2002, Archives de pédiatrie.

Molecular screening for cancer treatment optimization (MOSCATO 01) in pediatric patients: First feasibility results of a prospective molecular stratification trial.

P. Varlet, T. Baère, S. Puget, 2014 .

[Ifosfamide induced encephalopathy: 15 observations].

A. Paci, J. Grill, P. Sabouraud, 2006, Archives de pédiatrie.

Imaging features to distinguish posterior fossa ependymoma subgroups

P. Varlet, N. Boddaert, S. Puget, 2023, European Radiology.

Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts

D. Frappaz, D. Figarella-Branger, D. Ellison, 2011, Journal of Negative Results in BioMedicine.

A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival

S. Puget, J. Grill, M. Debily, 2019, Oncogene.

Current and evolving knowledge of prognostic factors for pediatric ependymomas.

S. Puget, F. Andreiuolo, J. Grill, 2013, Future oncology.

DIPG-20. PRE-RANDOMISATION CENTRAL REVIEW AND REAL-TIME BIOMARKERS SCREENING IN THE MULTICENTRE BIOLOGICAL MEDICINE FOR DIPG ERADICATION (BIOMEDE) TRIAL: LESSONS LEARNT FROM THE FIRST 120 BIOPSIES

P. Varlet, S. Puget, F. Andreiuolo, 2018, Neuro-Oncology.

Neurofibromatosis type 1 mosaicism in patients with constitutional mismatch repair deficiency

P. Varlet, L. Guerrini-Rousseau, J. Grill, 2023, Journal of medical genetics.

Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma

P. Varlet, S. Puget, T. Roujeau, 2011, Journal of Neuro-Oncology.

Case Report: Zolpidem’s paradoxical restorative action: A case report of functional brain imaging

M. Zilbovicius, R. Gaillard, H. Lemaître, 2023, Frontiers in Neuroscience.

Beta‐catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

E. Barillot, P. Varlet, O. Delattre, 2009, The Journal of pathology.

Neurocognitive outcome and Academic achievement in adult survivors of childhood medulloblastoma

S. Puget, J. Grill, G. Dellatolas, 2012 .

Disrupted sensorimotor synchronization, but intact rhythm discrimination, in children treated for a cerebellar medulloblastoma.

J. Provasi, H. Perdry, V. Doyère, 2014, Research in developmental disabilities.

Clinicopathologic prognostic factors in childhood atypical teratoid and rhabdoid tumor of the central nervous system

N. André, P. Varlet, D. Frappaz, 2012, Cancer.

Pediatric infratentorial gangliogliomas: a retrospective series.

N. Boddaert, S. Puget, T. Roujeau, 2007, Journal of neurosurgery.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

David T. W. Jones, R. Eils, M. Wolter, 2016, Cell.

Utility of Cerebrospinal Fluid Cytology in Newly Diagnosed Childhood Ependymoma

J. Grill, S. Zacharoulis, M. Massimino, 2010, Journal of pediatric hematology/oncology.

Impact of ComBat and a Multi-Model approach to deal with multi-scanner and missing MRI data in a small cohort study. Application to H3K27M mutation prediction in patients with DIPG

Vincent Frouin, Frédérique Frouin, Jessica Goya-Outi, 2021, 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

Computation of reliable textural indices from multimodal brain MRI: suggestions based on a study of patients with diffuse intrinsic pontine glioma

Fanny Orlhac, I. Buvat, V. Frouin, 2018, Physics in medicine and biology.

Molecular Mechanisms Involved in the Chemical Instability of ONC201 and Methods to Counter Its Degradation in Solution

J. Grill, B. Do, M. Paul, 2023, Pharmaceutics.