A. Gomes

发表

Familial Hypertrophic Cardiomyopathy Mutations in the Regulatory Light Chains of Myosin Affect Their Structure, Ca2+Binding, and Phosphorylation*

J. Stull, D. Szczesna, D. Ghosh, 2001, The Journal of Biological Chemistry.

Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment.

A. Gomes, S. Bodine, D. Hwee, 2011, American journal of physiology. Endocrinology and metabolism.

Mapping the Murine Cardiac 26S Proteasome Complexes

P. Ping, E. Stefani, A. Gomes, 2006, Circulation research.

The need for agriculture phenotyping: "moving from genotype to phenotype".

S. Briggs, A. Gomes, P. Righetti, 2013, Journal of proteomics.

Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts.

A. Gomes, S. Goswami, B. Hammock, 2016, International journal of cardiology.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Aha Scientific Statement Transformative Impact of Proteomics on Cardiovascular Health and Disease a Scientific Statement from the American Heart Association

M. Mayr, D. K. Arrell, A. Terzic, 2022 .

Different Functional Properties of Troponin T Mutants That Cause Dilated Cardiomyopathy*

A. Gomes, J. Potter, W. Kerrick, 2003, Journal of Biological Chemistry.

Dynamic regulation of the proteasome by systolic overload.

A. Gomes, T. Carbonell, 2015, Journal of molecular and cellular cardiology.

Contrasting Proteome Biology and Functional Heterogeneity of the 20 S Proteasome Complexes in Mammalian Tissues*S

P. Ping, E. Stefani, Haojie Lu, 2009, Molecular & Cellular Proteomics.

Delineation of Molecular Pathways Involved in Cardiomyopathies Caused by Troponin T Mutations*

Jennifer E. Gilda, A. Gomes, F. Witzmann, 2016, Molecular & Cellular Proteomics.

Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice

A. Gomes, L. Deldicque, M. Francaux, 2014, BMC Musculoskeletal Disorders.

Pregnancy Is Associated with Decreased Cardiac Proteasome Activity and Oxidative Stress in Mice

M. Eghbali, A. Gomes, Andrea Iorga, 2012, PloS one.

Upregulation of proteasome activity in muscle RING finger 1‐null mice following denervation

A. Gomes, S. Bodine, J. Furlow, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Non-antigen processing immunoproteasomes in diabetic hearts?

A. Gomes, S. Dewey, 2010, Journal of molecular and cellular cardiology.

The use of biophysical proteomic techniques in advancing our understanding of diseases

A. Gomes, Ziyou Cui, Qian Xu, 2012, Biophysical Reviews.

Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart.

Jonathan P. Davis, A. Gomes, J. Potter, 2004, The Journal of biological chemistry.

The Role of Troponins in Muscle Contraction

A. Gomes, J. Potter, D. Szczesna‐Cordary, 2002, IUBMB life.

Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature.

A. Gomes, Chin-Shang Li, A. Knowlton, 2019, American journal of physiology. Heart and circulatory physiology.

Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors.

F. Haj, A. Gomes, B. Hammock, 2017, Prostaglandins & other lipid mediators.

Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin.

A. Gomes, J. Benovic, You-Me Kim, 2003, Biochemistry.

MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury

A. Gomes, T. Carbonell, 2020, Redox biology.

A Common Feature of Pesticides: Oxidative Stress—The Role of Oxidative Stress in Pesticide-Induced Toxicity

A. Gomes, Rasheed O Sule, Liam Condon, 2022, Oxidative medicine and cellular longevity.

Protease activated receptors in cardiovascular function and disease

J. A. Barnes, A. Gomes, Shamjeet Singh, 2004, Molecular and Cellular Biochemistry.

Western Blotting Inaccuracies with Unverified Antibodies: Need for a Western Blotting Minimal Reporting Standard (WBMRS)

Jennifer E. Gilda, Jenice X. Cheah, A. Gomes, 2015, PloS one.

Strengthening US Food Policies and Programs to Promote Equity in Nutrition Security: A Policy Statement From the American Heart Association

A. Gomes, C. Gardner, A. Thorndike, 2022, Circulation.

Molecular and Cellular Aspects of Troponin Cardiomyopathies

A. Gomes, J. Potter, 2004, Annals of the New York Academy of Sciences.

Selective Degradation of Annexins by Chaperone-mediated Autophagy*

J. A. Barnes, A. Gomes, A. Cuervo, 2000, The Journal of Biological Chemistry.

Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers

A. Gomes, Jun Yang, B. Hammock, 2020, Scientific Reports.

Functional Consequences of the Human Cardiac Troponin I Hypertrophic Cardiomyopathy Mutation R145G in Transgenic Mice*

A. Gomes, J. Potter, W. Kerrick, 2008, Journal of Biological Chemistry.

Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell–Dependent Endothelial Cell Apoptosis

M. Eghbali, Xia Yang, A. Gomes, 2020, Hypertension.

Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats

A. Gomes, K. Baar, H. Langer, 2022, Cell Death & Disease.

Characterization of Troponin T Dilated Cardiomyopathy Mutations in the Fetal Troponin Isoform*

A. Gomes, J. Potter, W. Kerrick, 2005, Journal of Biological Chemistry.

Determinants of Potency on α-Conotoxin MII, a Peptide Antagonist of Neuronal Nicotinic Receptors

A. Gomes, J. McIntosh, A. Malhotra, 2004 .

Loss of ABCG1 Results in Chronic Pulmonary Inflammation1

P. Ping, P. Edwards, A. Gomes, 2008, The Journal of Immunology.

The Miscommunicative Cardiac Cell: When Good Proteins Go Bad

A. Gomes, J. Potter, G. Venkatraman, 2005, Annals of the New York Academy of Sciences.

Pulmonary Inflammation Loss of ABCG1 Results in Chronic

P. Ping, A. Gomes, Á. Baldán, 2013 .

Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems.

Jonathan P. Davis, A. Gomes, B. Liu, 2010, Biochemistry.

Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice

Jennifer E. Gilda, A. Gomes, Jun Yang, 2017, Behavioural Brain Research.

The functional significance of the last 5 residues of the C-terminus of cardiac troponin I.

Jennifer E. Gilda, A. Gomes, P. Chase, 2016, Archives of biochemistry and biophysics.

Stain-Free total protein staining is a superior loading control to β-actin for Western blots.

Jennifer E. Gilda, A. Gomes, 2013, Analytical biochemistry.

Perspective: The Antibody Validation Webinar Series from The Antibody Society

Bradbury, F. Lund-Johansen, J. Trimmer, 2020 .

Spatiotemporal Multi-Omics–Derived Atlas of Calcific Aortic Valve Disease

A. Gomes, 2018, Circulation.

Western Blotting Using In-Gel Protein Labeling as a Normalization Control: Advantages of Stain-Free Technology.

A. Gomes, Rômulo L. S. Neris, Andrea Marie Chua Dobles, 2021, Methods in molecular biology.

Editorial: Post-translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease

A. Gomes, H. Su, M. Ranek, 2021, Frontiers in Physiology.

Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice.

J. Seidman, R. Lieber, C. Seidman, 2014, Human molecular genetics.

The necessity of and strategies for improving confidence in the accuracy of western blots

Jennifer E. Gilda, A. Gomes, R. Ghosh, 2014, Expert review of proteomics.

Protein purification and analysis: next generation Western blotting techniques

A. Gomes, M. Mishra, S. Tiwari, 2017, Expert review of proteomics.

Ponceau S waste: Ponceau S staining for total protein normalization.

A. Gomes, S. Tiwari, Samantha Wallace, 2019, Analytical biochemistry.

PEST sequences in calmodulin-binding proteins

J. A. Barnes, A. Gomes, 1995, Molecular and Cellular Biochemistry.

β-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model.

Jorge A Negroni, Donald M Bers, Eleonora Grandi, 2015, Journal of molecular and cellular cardiology.

The Functional Properties of Human Slow Skeletal Troponin T Isoforms in Cardiac Muscle Regulation*

A. Gomes, J. Potter, T. Miller, 2012, The Journal of Biological Chemistry.

Cardiac Troponin T Isoforms Affect the Ca2+Sensitivity and Inhibition of Force Development

A. Gomes, G. Guzman, J. Potter, 2002, The Journal of Biological Chemistry.

Amino Acid Changes at Arginine 204 of Troponin I Result in Increased Calcium Sensitivity of Force Development

A. Gomes, Ziyou Cui, S. Dewey, 2016, Front. Physiol..

A mutation in the N-terminus of troponin I that is associated with hypertrophic cardiomyopathy affects the Ca(2+)-sensitivity, phosphorylation kinetics and proteolytic susceptibility of troponin.

A. Gomes, J. Potter, K. Harada, 2005, Journal of molecular and cellular cardiology.

Mutations in Human Cardiac Troponin I That Are Associated with Restrictive Cardiomyopathy Affect Basal ATPase Activity and the Calcium Sensitivity of Force Development*

Aldrin V Gomes, A. Gomes, J. Potter, 2005, Journal of Biological Chemistry.

Role of troponin T in disease

J. A. Barnes, A. Gomes, J. Potter, 2004, Molecular and Cellular Biochemistry.

Functional Analysis of a Troponin I (R145G) Mutation Associated with Familial Hypertrophic Cardiomyopathy*

A. Gomes, J. Potter, Jiaju Zhao, 2002, The Journal of Biological Chemistry.

Abnormal Contractile Function in Transgenic Mice Expressing a Familial Hypertrophic Cardiomyopathy-linked Troponin T (I79N) Mutation*

D. Szczesna, A. Gomes, J. Potter, 2001, The Journal of Biological Chemistry.

Genetics of Proteasome Diseases

A. Gomes, 2013, Scientifica.

Cation Signaling in Striated Muscle Contraction

A. Gomes, J. Potter, K. Harada, 2002 .

Key Characteristics of Cardiovascular Toxicants

L. Lind, V. Cogliano, L. Zeise, 2021, Environmental health perspectives.

How to Design a Cardiovascular Proteomics Experiment

Merry L. Lindsey, Aldrin V. Gomes, Stanley V. Smith, 2016 .

Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function?

A. Gomes, J. Potter, Audrey N. Chang, 2010, Journal of molecular and cellular cardiology.

Malignant and benign mutations in familial cardiomyopathies: insights into mutations linked to complex cardiovascular phenotypes.

A. Gomes, S. Dewey, Qian Xu, 2010, Journal of molecular and cellular cardiology.

Cellular and molecular aspects of familial hypertrophic cardiomyopathy caused by mutations in the cardiac troponin I gene

A. Gomes, J. Potter, 2004, Molecular and Cellular Biochemistry.

Acute resistance exercise activates rapamycin‐sensitive and ‐insensitive mechanisms that control translational activity and capacity in skeletal muscle

A. Gomes, S. Bodine, Leslie M. Baehr, 2016, The Journal of physiology.

Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System

A. Gomes, T. Carbonell, S. Dewey, 2016, Oxidative medicine and cellular longevity.

Proteomic analysis of hearts from Akita mice suggests that increases in soluble epoxide hydrolase and antioxidative programming are key changes in early stages of diabetic cardiomyopathy.

A. Gomes, F. Witzmann, Xianyin Lai, 2013, Journal of proteome research.

Proteomic analysis of physiological versus pathological cardiac remodeling in animal models expressing mutations in myosin essential light chains

Jennifer E. Gilda, Jenice X. Cheah, A. Gomes, 2015, Journal of Muscle Research and Cell Motility.

Identification of the Immunoproteasome as a Novel Regulator of Skeletal Muscle Differentiation

A. Gomes, Ziyou Cui, S. Hwang, 2013, Molecular and Cellular Biology.

Different effects of the nonsteroidal anti-inflammatory drugs meclofenamate sodium and naproxen sodium on proteasome activity in cardiac cells.

Jennifer E. Gilda, A. Gomes, Ziyou Cui, 2016, Journal of molecular and cellular cardiology.

Cardioproteomics: advancing the discovery of signaling mechanisms involved in cardiovascular diseases.

A. Gomes, Ziyou Cui, S. Dewey, 2011, American journal of cardiovascular disease.

Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond.

Jennifer E. Gilda, Sarah B. Scruggs, P. Ping, 2014, Journal of molecular and cellular cardiology.

Proteasome dysfunction in cardiomyopathies

Jennifer E. Gilda, A. Gomes, 2017, The Journal of physiology.

Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association

Yu-Fang Jin, Catherine E Costello, Merry L Lindsey, 2015, Circulation.

Non-steroidal anti-inflammatory drugs and increased risk of sudden cardiac death

Jennifer E. Gilda, A. Gomes, Ziyou Cui, 2013 .

Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy.

A. Gomes, T. Kensler, E. Abel, 2013, Cardiovascular research.

Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen

A. Gomes, B. Phinney, M. Salemi, 2020, Scientific Reports.

NSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen Species

A. Gomes, A. Alajbegović, R. Ghosh, 2015, Oxidative medicine and cellular longevity.

Sarcomeric perturbations of myosin motors lead to dilated cardiomyopathy in genetically modified MYL2 mice

T. Irving, A. Gomes, D. Szczesna‐Cordary, 2018, Proceedings of the National Academy of Sciences.

Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain

A. Gomes, B. Hammock, K. Wagner, 2020, Neurotherapeutics.

Proteomics, Metabolomics, and Immunomics on Microparticles Derived From Human Atherosclerotic Plaques

Manuel Mayr, John R Griffiths, Chantal M Boulanger, 2009, Circulation. Cardiovascular genetics.

Western blotting (immunoblotting): history, theory, uses, protocol and problems.

A. Gomes, Rasheed Sule, Rasheed Sule, 2023, BioTechniques.

Proteolytic signals in the primary structure of annexins

J. A. Barnes, A. Gomes, 2002, Molecular and Cellular Biochemistry.

Structural Determinants for Phosphatidic Acid Regulation of Phospholipase C-β1*

A. Gomes, C. Arana, E. Ross, 2006, Journal of Biological Chemistry.

Spectroscopic characterization of the calmodulin-binding and autoinhibitory domains of calcium/calmodulin-dependent protein kinase I.

J. A. Barnes, H. Vogel, A. Gomes, 2004, Archives of biochemistry and biophysics.

Spectroscopic characterization of the interaction between calmodulin-dependent protein kinase I and calmodulin.

J. A. Barnes, H. Vogel, A. Gomes, 2000, Archives of biochemistry and biophysics.

Crude and purified proteasome activity assays are affected by type of microplate.

Jennifer E. Gilda, A. Gomes, Ziyou Cui, 2014, Analytical biochemistry.

Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice

T. Irving, A. Gomes, D. Szczesna‐Cordary, 2017, Cardiovascular research.

The use of biophysical proteomic techniques in advancing our understanding of diseases

A. Gomes, Ziyou Cui, Qian Xu, 2012, Biophysical Reviews.

Nrf2 deficiency promotes apoptosis and impairs PAX7/MyoD expression in aging skeletal muscle cells.

Christopher J. Davidson, A. Gomes, Nancy Atieno, 2014, Free radical biology & medicine.

Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.

Qingbo Xu, M. Mayr, P. Ping, 2009, Journal of molecular and cellular cardiology.

The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells.

X. Chen, A. Gomes, F. Fontanesi, 2022, Developmental cell.

Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Cardiac Dysfunction

A. Gomes, Jun Yang, B. Hammock, 2021, Cardiovascular Drugs and Therapy.

Synergizing Proteomic and Metabolomic Data to Study Cardiovascular Systems

Jennifer E. Gilda, Clifford D.L. Folmes, Jenice X. Cheah, 2016 .

Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB

Jennifer E. Gilda, S. Hwang, A. Gomes, 2014, Anti-cancer drugs.

Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure.

D. Bernstein, A. Gomes, Xuejun Wang, 2013, American journal of physiology. Heart and circulatory physiology.

Myocardial Ischemic Preconditioning Preserves Postischemic Function of the 26S Proteasome Through Diminished Oxidative Damage to 19S Regulatory Particle Subunits

A. Gomes, Ping Wang, S. Kivity, 2010, Circulation research.

Cardiac myosin binding protein C phosphorylation in heart failure

Jennifer E. Gilda, A. Gomes, 2013 .

Static and dynamic properties of the HCM myocardium.

A. Gomes, S. Dewey, Qian Xu, 2010, Journal of molecular and cellular cardiology.

Protein degradation by the 26S proteasome system in the normal and stressed myocardium.

P. Ping, A. Gomes, Chenggong Zong, 2006, Antioxidants & redox signaling.

Effect of the Troponin I Restrictive Cardiomyopathy Mutation R145W on Protein Expression in Murine Murine Hearts

A. Gomes, Ziyou Cui, S. Hwang, 2013 .

The Murine Cardiac 26S Proteasome: An Organelle Awaiting Exploration

P. Ping, T. Vondriska, A. Gomes, 2005, Annals of the New York Academy of Sciences.

Fatty acid composition and possible health effects of coconut constituents.

J. A. Barnes, A. Gomes, D. Pehowich, 2000, The West Indian medical journal.

Western blotting using in-gel protein labeling as a normalization control: stain-free technology.

Jennifer E. Gilda, A. Gomes, 2015, Methods in molecular biology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Slow‐twitch skeletal muscle defects accompany cardiac dysfunction in transgenic mice with a mutation in the myosin regulatory light chain

Jenice X. Cheah, T. Irving, A. Gomes, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Improving the sensitivity of traditional Western blotting via Streptavidin containing Poly‐horseradish peroxidase (PolyHRP)

A. Gomes, B. Hammock, M. Mishra, 2019, Electrophoresis.

Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes.

D. Bers, A. Gomes, J. Puglisi, 2014, Archives of biochemistry and biophysics.

Mammalian Proteasome Subpopulations with Distinct Molecular Compositions and Proteolytic Activities*

Peipei Ping, Chenggong Zong, Aldrin V. Gomes, 2007, Molecular & Cellular Proteomics.

Regulation of Murine Cardiac 20S Proteasomes: Role of Associating Partners

Peipei Ping, Chenggong Zong, Aldrin V. Gomes, 2006, Circulation research.

Major proteins of yam bean tubers.

J. A. Barnes, A. Gomes, G. Sirju-Charran, 1997, Phytochemistry.

Proteomic analysis of physiological versus pathological cardiac remodeling in animal models expressing mutations in myosin essential light chains

Jennifer E. Gilda, Jenice X. Cheah, A. Gomes, 2015, Journal of Muscle Research and Cell Motility.

Protein phosphatases are pest containing proteins

J. A. Barnes, A. Gomes, 1997, Biochemistry and molecular biology international.

left ventricular pressure-volume loops in rats dexamethasone treatment: hemodynamic follow-up by Long-term cardiovascular effects of neonatal

A. Gomes, P. Steendijk, S. Bodine, 2015 .

The Antibody Society’s antibody validation webinar series

Anita Bandrowski, Andreas Plückthun, James S Trimmer, 2020, mAbs.

A Ketogenic Diet in Combination with Gemcitabine Mitigates Pancreatic Cancer-Associated Cachexia in Male and Female KPC Mice

Fang Wang, A. Gomes, K. Baar, 2023, International journal of molecular sciences.

Incorrect Molecular Weights due to inaccurate Prestained Protein Molecular Weight Markers that are used for Gel Electrophoresis and Western Blotting

A. Gomes, Rômulo L. S. Neris, Ajuni Kaur, 2020, bioRxiv.

Antibodies: Half of samples fail protein-blot tests

A. Gomes, Matt Landry, 2016, Nature.

Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen

A. Gomes, B. Phinney, M. Salemi, 2020, Scientific Reports.

PSS174 - Nrf2 Deficiency Prevents Reductive Stress Induced Hypertrophic Cardiomyopathy

A. Gomes, T. Kensler, E. Abel, 2013 .

Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy.

A. Gomes, T. Kensler, E. Abel, 2013, Cardiovascular research.

Cardiomyopathies: Classification, Clinical Characterization, and Functional Phenotypes

A. Gomes, D. Szczesna‐Cordary, Jeffrey R. Moore, 2012, Biochemistry research international.

Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.

Qingbo Xu, M. Mayr, P. Ping, 2009, Journal of molecular and cellular cardiology.