A. Avdeef

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Absorption classification of oral drugs based on molecular surface properties.

Christel A. S. Bergström, K. Luthman, P. Artursson, 2003, Journal of medicinal chemistry.

Absorption and Drug Development: Solubility, Permeability, and Charge State

Alex Avdeef, A. Avdeef, 2003 .

Partitioning into Liposomes

Alex Avdeef, A. Avdeef, 2003 .

Coexistence of passive and carrier-mediated processes in drug transport

Li Di, Gerhard F. Ecker, Manfred Kansy, 2010, Nature Reviews Drug Discovery.

pH‐metric Solubility. 1. Solubility‐pH Profiles from Bjerrum Plots. Gibbs Buffer and pKa in the Solid State

Alex Avdeef, A. Avdeef, 1998 .

Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques

B. Testa, A. Avdeef, B. Testa, 2002, Cellular and Molecular Life Sciences CMLS.

Physicochemical Profiling (Solubility, Permeability and Charge State)

Alex Avdeef, A. Avdeef, 2001 .

pH-metric log P. II: Refinement of partition coefficients and ionization constants of multiprotic substances.

A. Avdeef, A Avdeef, Alex Avdeef, 1993, Journal of pharmaceutical sciences.

Permeation of permanently positive charged molecules through artificial membranes--influence of physico-chemical properties.

M. Kansy, A. Avdeef, H. Fischer, 2007, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Classification Analysis of P-Glycoprotein Substrate Specificity

Remigijus Didziapetris, Pranas Japertas, Alex Avdeef, 2003, Journal of drug targeting.

Classification structure-activity relations (C-SAR) in prediction of human intestinal absorption.

Remigijus Didziapetris, Pranas Japertas, Donatas Zmuidinavicius, 2003, Journal of pharmaceutical sciences.

PAMPA--critical factors for better predictions of absorption.

Li Di, Manfred Kansy, Kiyohiko Sugano, 2007, Journal of pharmaceutical sciences.

Acid-base cosolvent method for determining aqueous permeability of amiodarone, itraconazole, tamoxifen, terfenadine and other very insoluble molecules.

Alex Avdeef, A. Avdeef, Oksana Tsinman, 2004, Chemical & pharmaceutical bulletin.

pH-Metric log P. 3. Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances

John Comer, Alex Avdeef, A. Avdeef, 1993 .

Potentiometric pKa determination of water-insoluble compounds: validation study in methanol/water mixtures

Alex Avdeef, Karl Box, A. Avdeef, 1997 .

In Vitro Assays for Assessing BBB Permeability

A. Avdeef, M. Deli, W. Neuhaus, 2015 .

Permeability: Caco‐2/MDCK

A. Avdeef, 2012 .

Prediction of aqueous intrinsic solubility of druglike molecules using Random Forest regression trained with Wiki-pS0 database

A. Avdeef, 2020, ADMET & DMPK.

Permeability: Blood–Brain Barrier

A. Avdeef, 2012 .

P-glycoprotein deficient mouse in situ blood-brain barrier permeability and its prediction using an in combo PAMPA model.

A. Avdeef, R. Béliveau, Claude Dagenais, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A PAMPA Study of the Permeability‐Enhancing Effect of New Ceramide Analogues

A. Avdeef, J. Kökösi, K. Takács-Novák, 2009, Chemistry & biodiversity.

Weighting scheme for regression analysis using pH data from acid—base titrations

A. Avdeef, 1983 .

Determination of protonation macro- and microconstants and octanol/water partition coefficient of the antiinflammatory drug niflumic acid.

A. Avdeef, K. Box, K. Takács-Novák, 1994, Journal of pharmaceutical and biomedical analysis.

Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat—Biophysical Model and Predictions Based on Caco-2

M. Bermejo, A. Avdeef, A. Dahan, 2017, Pharmaceutical Research.

Phosphate Precipitates and Water-Soluble Aggregates in Re-analyzed Solubility-pH Data of Twenty-five Basic Drugs

A. Avdeef, 2014 .

Bjerrum plots for the determination of systematic concentration errors in titration data

A. Avdeef, Jessica A Brown, D. Kearney, 1982 .

Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pHmax Domains with a Gibbs Phase Rule "Soft" Constraints.

A. Avdeef, A. Serajuddin, Tatjana Ž Verbić, 2022, Molecular pharmaceutics.

Potentiometric CheqSol and Standardized Shake-Flask Solubility Methods are Complimentary Tools in Physicochemical Profiling.

A. Avdeef, Xavier Subirats, C. Ràfols, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Biorelevant pK(a) (37 °C) predicted from the 2D structure of the molecule and its pK(a) at 25 °C.

A. Avdeef, Na Sun, 2011, Journal of pharmaceutical and biomedical analysis.

Cocrystal Solubility Product Prediction Using an in combo Model and Simulations to Improve Design of Experiments

A. Avdeef, 2018, Pharmaceutical Research.

Equilibrium solubility measurement of ionizable drugs - consensus recommendations for improving data quality

A. Avdeef, E. Bosch, E. Boldyreva, 2016 .

High‐Throughput Solubility, Permeability, and the MAD PAMPA Model

A. Avdeef, 2007 .

Miniaturized Rotating Disk Intrinsic Dissolution Rate Measurement: Effects of Buffer Capacity in Comparisons to Traditional Wood’s Apparatus

Alex Avdeef, A. Avdeef, Oksana Tsinman, 2008, Pharmaceutical Research.

PAMPA–Excipient Classification Gradient Map

M. Kansy, A. Avdeef, Björn Wagner, 2006, Pharmaceutical Research.

Accurate measurements of the concentration of hydrogen ions with a glass electrode: calibrations using the Prideaux and other universal buffer solutions and a computer-controlled automatic titrator

A. Avdeef, J. Bucher, 1978 .

In situ Fiber Optic Dissolution Monitoring of a Vitamin B12 Solid Dosage Formulation

A. Avdeef, C. Toher, P. Nielsen, 2003 .

A versatile potentiometric analyzer. Part two. Multiple known addition and Gran titration techniques.

A. Avdeef, J. Comer, 1987 .

Caco-2 permeability of weakly basic drugs predicted with the double-sink PAMPA pKa(flux) method.

P. Artursson, L. Lazorova, A. Avdeef, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

COORDINATION CHEMISTRY OF MICROBIAL IRON TRANSPORT COMPOUNDS. 19. STABILITY CONSTANTS AND ELECTROCHEMICAL BEHAVIOR OF FERRIC ENTEROBACTIN AND MODEL COMPLEXES

A. Avdeef, C. Carrano, K. Raymond, 1979 .

Coordination chemistry of microbial iron transport compounds. 9. Stability constants for catechol models of enterobactin

A. Avdeef, K. Raymond, S. Sofen, 1978 .

Predicting the human jejunal permeability and fraction absorbed of fluoroquinolones based on a biophysical model.

A. Avdeef, K. Tam, Chenyin Wang, 2014, Bio-medical materials and engineering.

Multi-lab intrinsic solubility measurement reproducibility in CheqSol and shake-flask methods

A. Avdeef, 2019, ADMET & DMPK.

Trends in PhysChem Properties of Newly Approved Drugs over the Last Six Years; Predicting Solubility of Drugs Approved in 2021

M. Kansy, A. Avdeef, 2022, Journal of Solution Chemistry.

Predicting Solubility of Newly-Approved Drugs (2016–2020) with a Simple ABSOLV and GSE(Flexible-Acceptor) Consensus Model Outperforming Random Forest Regression

M. Kansy, A. Avdeef, 2022, Journal of Solution Chemistry.

Understanding the pH Dependence of Supersaturation State—A Case Study of Telmisartan

A. Avdeef, A. Farkas, J. Madarász, 2022, Pharmaceutics.

In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.

A. Avdeef, N. Abbott, Siti R. Yusof, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

How well can in vitro brain microcapillary endothelial cell models predict rodent in vivo blood-brain barrier permeability?

A. Avdeef, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Do you know your r2?

A. Avdeef, 2020, ADMET & DMPK.

Physicochemical profiling (solubility, permeability and charge state).

A. Avdeef, Alex Avdeef, 2001, Current topics in medicinal chemistry.

Membrane–Water partitioning, membrane permeability, and baseline toxicity of the parasiticides ivermectin, albendazole, and morantel

A. Avdeef, Jung-Hwan Kwon, M. Richter, 2008, Environmental toxicology and chemistry.

Crystal and molecular structure of tris(2,4-pentanedionato)manganese(III), Mn(O2C5H7)3, a distorted complex as predicted by Jahn-Teller arguments

A. Avdeef, J. Fackler, 1974 .

Crystal and molecular structure of tris(tropolonato)manganese(III), Mn(O2C7H5)3, a high-spin complex having structural features consistent with Jahn-Teller behavior for two distinct MnO6 centers

A. Avdeef, J. Fackler, J. Costamagna, 1974 .

Studies of the cubane cluster of copper(I). A modified self-consistent charge and configuration molecular orbital investigation of the cluster containing the Cu8S124- core

A. Avdeef, J. Fackler, 1978 .

3. pKa Determination

A. Avdeef, 2012 .

PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent-water mixtures.

A. Avdeef, K. Tam, J. Comer, 1999, Journal of pharmaceutical and biomedical analysis.

Cadmium binding by biological ligands. 5. Solution studies of cadmium and zinc binding by sulfhydryl ligands N,N'-dimethyl-N,N'-bis(2-mercaptoethyl)ethylenediamine and (2-mercaptoethyl)amine

A. Avdeef, Alfred R. Chemotti, Frances Hartenstein, 1992 .

Predicting the exposure and antibacterial activity of fluoroquinolones based on physicochemical properties.

A. Avdeef, K. Tam, K. Takács-Novák, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Cadmium binding by biological ligands. 2 [1]. Formation of protonated and polynuclear complexes between cadmium and 2-mercaptoethylamine

A. Avdeef, Jessica A. Brown, 1984 .

Reversible oxygen carriers. Synthesis and structure of .mu.-dioxygen-bis[N,N'-ethylenebis(salicylideniminato)piperidinecobalt] acetonate piperidinate (C5H11NCoSalen)2(O2).cntdot.0.67(CH3)2CO.cntdot.0.33C5H11N7

W. Schaefer, A. Avdeef, 1976 .

Sulfur chelates. XVI. Chemical properties of oxidized nickel(II) dithiocarbamates. X-ray crystal structure of tris(N,N-dibutyldithiocarbamato)nickel(IV)bromide, NiC27H54N3S6Br

R. G. Fischer, A. Avdeef, J. Fackler, 1973 .

Structural characterization of tris(N,N-di-n-butyldithiocarbamato)nickel(IV) bromide. A Ni-S6 complex with unusual chemical properties

R. G. Fischer, A. Avdeef, J. Fackler, 1970 .

Calibration of copper ion selective electrode response to pCu 19

Alex Avdeef, A. Avdeef, Jerome. Zabronsky, 1983 .

Two isostructural actinide .pi. complexes. Crystal and molecular structure of bis(cyclooctatetraenyl)uranium(IV), U(C8H8)2, and bis(cyclooctatetraenyl)thorium(IV), Th(C8H8)2

K. Hodgson, A. Avdeef, K. Raymond, 1972 .

Reversible oxygen carriers. The synthesis and low temperature (-171.degree.) structure of an unstable monomeric dioxygen adduct of N,N'-(1,1,2,2-tetramethyl)ethylenebis(3-fluorosalicylideniminato)(1-methylimidazole)cobalt(II), Co(3-F-Saltmen)(1-Me-Imid)(O2).2Me2CO

W. Schaefer, A. Avdeef, W. P. Schaefer, 1976 .

pH-Metric logP 10. Determination of Liposomal Membrane-Water Partition Coefficients of lonizable Drugs

A. Avdeef, K. Tam, J. Comer, 1998, Pharmaceutical Research.

Crystal and molecular structure of tris(tropolonato)manganese(III), Mn(O2C7H5)3, a high-spin complex having structural features consistent with Jahn-Teller behavior for two distinct MnO6 centers

A. Avdeef, J. Fackler, J. Costamagna, 1974 .

Solubility of sparingly-soluble ionizable drugs.

A. Avdeef, 2007, Advanced drug delivery reviews.

pH-Metric Solubility. 2: Correlation Between the Acid-Base Titration and the Saturation Shake-Flask Solubility-pH Methods

Alex Avdeef, A. Avdeef, Cynthia M. Berger, 2004, Pharmaceutical Research.

PAMPA--a drug absorption in vitro model 11. Matching the in vivo unstirred water layer thickness by individual-well stirring in microtitre plates.

A. Avdeef, Oksana Tsinman, P. Nielsen, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Assessment of Distribution‐pH Profiles

A. Avdeef, 2008 .

Perspectives in solubility measurement and interpretation

Christel A. S. Bergström, A. Avdeef, 2019, ADMET & DMPK.

Phenothiazines solution complexity - Determination of pKa and solubility-pH profiles exhibiting sub-micellar aggregation at 25 and 37°C.

A. Avdeef, E. Bosch, Xavier Subirats, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Absorption-excipient-pH classification gradient maps: sparingly soluble drugs and the pH partition hypothesis.

M. Kansy, A. Avdeef, Stefanie Bendels, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Solubility-Excipient Classification Gradient Maps

M. Kansy, A. Avdeef, Stefanie Bendels, 2007, Pharmaceutical Research.

Bis(triphenylphosphine)ethyltrithiocarbonatocopper(I)

A. Avdeef, J. Fackler, 1975 .

Cocrystal solubility product analysis – Dual concentration‐pH mass action model not dependent on explicit solubility equations

A. Avdeef, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

pH-metric log P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values.

A. Avdeef, J. Comer, B. Slater, 1994, Journal of pharmaceutical sciences.

Lamivudine permeability study: a comparison between PAMPA, ex vivo and in situ Single-Pass Intestinal Perfusion (SPIP) in rat jejunum.

A. Avdeef, A. B. Dezani, T. M. Pereira, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Anomalous Solubility Behavior of Several Acidic Drugs

A. Avdeef, 2014 .

Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions Using Mass Spectrometry (ESI-Q-TOF-MS/MS).

A. Avdeef, E. Bosch, Xavier Subirats, 2021, Molecular pharmaceutics.

Solubility‐pH profile of desipramine hydrochloride in saline phosphate buffer: Enhanced solubility due to drug‐buffer aggregates

A. Avdeef, A. Serajuddin, Ankita V. Shah, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Cocrystal solubility-pH and drug solubilization capacity of sodium dodecyl sulfate – mass action model for data analysis and simulation to improve design of experiments

A. Avdeef, 2018, ADMET and DMPK.

Equilibrium solubility measurement of compounds with low dissolution rate by Higuchi's Facilitated Dissolution Method. A validation study

A. Avdeef, B. D. Anderson, K. Takács-Novák, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Absorption and drug development

Alex Avdeef, A. Avdeef, 2003 .

The rise of PAMPA

Alex Avdeef, A. Avdeef, 2005, Expert opinion on drug metabolism & toxicology.

Dissolution rate and apparent solubility of poorly soluble drugs in biorelevant dissolution media.

Na Sun, Christel A. S. Bergström, Christel A S Bergström, 2010, Molecular pharmaceutics.

pH-metric solubility. 3. Dissolution titration template method for solubility determination.

A. Avdeef, A Avdeef, C M Berger, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Coordination chemistry of microbial iron transport compounds. 9. Stability constants for catechol models of enterobactin

A. Avdeef, K. Raymond, S. Sofen, 1978 .

STBLTY: Methods for Construction and Refinement of Equilibrium Models

A. Avdeef, 1985 .

PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

Marival Bermejo, Virginia Merino, Alex Avdeef, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.

A. Avdeef, K. Tam, Oksana Tsinman, 2010, Journal of medicinal chemistry.

Skin-PAMPA: a new method for fast prediction of skin penetration.

Bálint Sinkó, Zsombor K Nagy, Alex Avdeef, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

pH‐Metric log P. Part 1. Difference Plots for Determining Ion‐Pair Octanol‐Water Partition Coefficients of Multiprotic Substances

Alex Avdeef, A. Avdeef, 1992 .

7. Permeability—PAMPA

A. Avdeef, 2012 .

Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition.

Li Di, Manfred Kansy, Kiyohiko Sugano, 2014, Molecular pharmaceutics.

A. Avdeef, 2015 .

PAMPA--a drug absorption in vitro model 13. Chemical selectivity due to membrane hydrogen bonding: in combo comparisons of HDM-, DOPC-, and DS-PAMPA models.

A. Avdeef, Oksana Tsinman, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In Vitro Permeability of Poorly Aqueous Soluble Compounds Using Different Solubilizers in the PAMPA Assay with Liquid Chromatography/Mass Spectrometry Detection

A. Avdeef, G. Carter, M. Tischler, 2003, Pharmaceutical Research.

The Critical Role of Passive Permeability in Designing Successful Drugs

L. Benet, M. Kansy, J. Houston, 2020, ChemMedChem.

Leakiness and Size Exclusion of Paracellular Channels in Cultured Epithelial Cell Monolayers–Interlaboratory Comparison

Alex Avdeef, A. Avdeef, 2010, Pharmaceutical Research.

Free metal and free ligand concentrations determined from titrations using only a pH electrode. Partial derivatives in equilibrium studies

A. Avdeef, K. Raymond, 1979 .

Findings of the Second Challenge to Predict Aqueous Solubility

Ioana Oprisiu, Antonio Llinas, Alex Avdeef, 2020, J. Chem. Inf. Model..

Advances in screening for membrane permeability: high-resolution PAMPA for medicinal chemists.

M. Kansy, A. Avdeef, H. Fischer, 2004, Drug discovery today. Technologies.

PAMPA--a drug absorption in vitro model 8. Apparent filter porosity and the unstirred water layer.

A. Avdeef, P. Nielsen, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Ionization, lipophilicity, and molecular modeling to investigate permeability and other biological properties of amlodipine.

A. Avdeef, G. Caron, G. Ermondi, 2004, Bioorganic & medicinal chemistry.

Cadmium binding by biological ligands. III: Five- and seven-cadmium binding in metallothionein: a detailed thermodynamic study

A. Avdeef, A. Żelazowski, J. Garvey, 1985 .

Octanol–Water Partitioning

A. Avdeef, 2012 .

Liposome–Water Partitioning

A. Avdeef, 2012 .

Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA method

Per Artursson, Sibylle Neuhoff, Alex Avdeef, 2005 .

Can small drugs predict the intrinsic aqueous solubility of ‘beyond Rule of 5’ big drugs?

M. Kansy, A. Avdeef, 2020, ADMET & DMPK.

Dissolution and Solubility

A. Avdeef, A. Foreman, D. Voloboy, 2007 .

Estimating the Water Solubilities of Crystalline Compounds from Their Chemical Structures Alone

James W. McFarland, Oleg A. Raevsky, Alex Avdeef, 2001, J. Chem. Inf. Comput. Sci..

Drug absorption in vitro model: filter-immobilized artificial membranes. 2. Studies of the permeability properties of lactones in Piper methysticum Forst.

M. Strafford, A. Avdeef, W. Chambliss, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Solubility Challenge Revisited after Ten Years, with Multilab Shake-Flask Data, Using Tight (SD ∼ 0.17 log) and Loose (SD ∼ 0.62 log) Test Sets

Antonio Llinas, Alex Avdeef, A. Avdeef, 2019, J. Chem. Inf. Model..

A New In Situ Brain Perfusion Flow Correction Method for Lipophilic Drugs Based on the pH-Dependent Crone-Renkin Equation

A. Avdeef, Na Sun, 2011, Pharmaceutical Research.

Physicochemical Selectivity of the BBB Microenvironment Governing Passive Diffusion—Matching with a Porcine Brain Lipid Extract Artificial Membrane Permeability Model

A. Avdeef, Oksana Tsinman, K. Tsinman, 2011, Pharmaceutical Research.

In vitro trans-monolayer permeability calculations: often forgotten assumptions.

Alex Avdeef, A. Avdeef, K. Youdim, 2003, Drug discovery today.

Miniaturization of Powder Dissolution Measurement and Estimation of Particle Size

Na Sun, Alex Avdeef, A. Avdeef, 2009, Chemistry & biodiversity.

Powder Dissolution Method for Estimating Rotating Disk Intrinsic Dissolution Rates of Low Solubility Drugs

Alex Avdeef, A. Avdeef, Konstantin Tsinman, 2009, Pharmaceutical Research.

Evidence-based approach to assess passive diffusion and carrier-mediated drug transport.

G. Ecker, M. Kansy, J. Houston, 2012, Drug discovery today.

Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.

A. Avdeef, S. Davis, D. Barrett, 1996, Journal of medicinal chemistry.

'Flexible-acceptor' General Solubility Equation for 'beyond Rule of 5' Drugs.

M. Kansy, A. Avdeef, 2020, Molecular pharmaceutics.

High‐throughput Measurement of Permeability Profiles

A. Avdeef, 2004 .

How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?

Alex Avdeef, A. Avdeef, K. Tam, 2010, Journal of medicinal chemistry.

PAMPA--a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa(flux)--optimized design (pOD-PAMPA).

A. Avdeef, J. Ruell, K. Tsinman, 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Impact of capillary flow hydrodynamics on carrier‐mediated transport of opioid derivatives at the blood‐brain barrier, based on pH‐dependent Michaelis‐Menten and Crone‐Renkin analyses

A. Avdeef, J. Abbott, Siti R. Yusof, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

pH-metric log P. 6. Effects of sodium, potassium, and N-CH3-D-glucamine on the octanol-water partitioning of prostaglandins E1 and E2.

A. Avdeef, K. Box, K. Takács-Novák, 1995, Journal of pharmaceutical sciences.

Solubility Temperature Dependence Predicted from 2D Structure

A. Avdeef, 2015 .

Structure-Lipophilicity Relationships of Neutral and Protonated β-Blockers, Part I, Intra- and Intermolecular Effects in Isotropic Solvent Systems

H. Girault, P. Carrupt, B. Testa, 1999 .

Integration of In Silico, In Vitro and In Situ Tools for the Preformulation and Characterization of a Novel Cardio-Neuroprotective Compound during the Early Stages of Drug Development

M. Bermejo, A. Avdeef, M. Cabrera-Pérez, 2022, Pharmaceutics.

Partitioning into Octanol

A. Avdeef, 2003 .

Advances in screening for membrane permeability: high-resolution PAMPA for medicinal chemists.

M. Kansy, A. Avdeef, H. Fischer, 2004, Drug discovery today. Technologies.

Salt solubility and disproportionation - uses and limitations of equations for pHmax and the in-silico prediction of pHmax.

A. Avdeef, K. Sugano, 2021, Journal of pharmaceutical sciences.

Measurement of pKa and log P of water-insoluble substances by potentiometric titration

A. Avdeef, J. Comer, 1993 .

Drug Ionization and Physicochemical Profiling

A. Avdeef, 2007 .