P. Fajer

发表

General method for multiparameter fitting of high-resolution EPR spectra using a simplex algorithm☆

P. Fajer, R. Bennett, C. Polnaszek, 1990 .

Dynamic modulation of the regulatory domain of myosin heads by pH, ionic strength, and RLC phosphorylation in synthetic myosin filaments.

J. Stull, P. Fajer, B. Adhikari, 1999, Biochemistry.

Improved Sequence Resolution by Global Analysis of Overlapped Peptides in Hydrogen/Deuterium Exchange Mass Spectrometry

P. Fajer, A. Marshall, G. Bou-Assaf, 2012, Journal of The American Society for Mass Spectrometry.

Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C.

P. Fajer, D. Gell, J. Mackay, 2013, Biochemistry.

Complexation and Calcium-Induced Conformational Changes in the Cardiac Troponin Complex Monitored by Hydrogen/Deuterium Exchange and FT-ICR Mass Spectrometry.

P. Fajer, M. Emmett, A. Marshall, 2011, International journal of mass spectrometry.

Experimental Considerations: Instrumentation and Methodology

L. Dalton, P. Fajer, B. Robinson, 2018 .

The concerted movement of the switch region of Troponin I in cardiac muscle thin filaments as tracked by conventional and pulsed (DEER) EPR.

P. Fajer, L. Brown, Nicole M Cordina, 2017, Journal of structural biology.

Explicit treatment of spin labels in modeling of distance constraints from dipolar EPR and DEER.

P. Fajer, E. Perozo, K. Sale, 2005, Journal of the American Chemical Society.

Ca2+-Induced PRE-NMR Changes in the Troponin Complex Reveal the Possessive Nature of the Cardiac Isoform for Its Regulatory Switch

T. Logan, P. Fajer, P. Curmi, 2014, PloS one.

Site directed spin labelling and pulsed dipolar electron paramagnetic resonance (double electron–electron resonance) of force activation in muscle

P. Fajer, 2005 .

APPENDIX 1 MOLECULAR MODELING OF SPIN LABELS

P. Fajer, K. Sale, M. Fajer, 2007 .

Analysis of dispersion-mode saturation-transfer ESR spectra. Application to model membranes

P. Fajer, D. Marsh, 1983 .

Regulatory and catalytic domain dynamics of smooth muscle myosin filaments.

P. Fajer, C. Cremo, Likai Song, 2006, Biochemistry.

Rotational motion of yeast cytochrome oxidase in phosphatidylcholine complexes studied by saturation-transfer electron spin resonance.

P. Fajer, P. Knowles, D. Marsh, 1989, Biochemistry.

Simulation of spin label structure and its implication in molecular characterization

P. Fajer, M. Fajer, Wei Yang, 2016 .

Interdomain orientation of cardiac Troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state

P. Fajer, D. Gell, J. Mackay, 2012, Protein science : a publication of the Protein Society.

Time-resolved rotational dynamics of phosphorescent-labeled myosin heads in contracting muscle fibers.

D. D. Thomas, P. Fajer, R. Bennett, 1990, Biochemistry.

Mn(II) binding by the anthracis repressor from Bacillus anthracis.

T. Logan, P. Fajer, A. Sienkiewicz, 2006, Biochemistry.

Measurement of rotational molecular motion by time-resolved saturation transfer electron paramagnetic resonance.

J. S. Hyde, D. D. Thomas, P. Fajer, 1986, Biophysical journal.

Distance and dynamics determination by W-band DEER and W-band ST-EPR

P. Fajer, M. Larion, Likai Song, 2010, European Biophysics Journal.

Dielectric resonator-based side-access probe for muscle fiber EPR study.

P. Fajer, A. Sienkiewicz, C. Scholes, 2000, Journal of magnetic resonance.

Oxidative stress-mediated protein conformation changes: ESR study of spin-labelled staphylococcal nuclease

P. Fajer, L. Forró, K. Pierzchala, 2007 .

Orientation and dynamics of myosin heads in aluminum fluoride induced pre-power stroke states: an EPR study.

P. Fajer, D. Raucher, Draien Raucher, 1994, Biochemistry.

Microwave and modulation field inhomogeneities and the effect of cavity Q in saturation transfer ESR spectra. Dependence on sample size

P. Fajer, D. Marsh, 1982 .

Standard conditions for the measurement of saturation-transfer ESR spectra

P. Fajer, D. Marsh, M. A. Hemminga, 1984 .

Sensitivity of saturation transfer ESR spectra to anisotropic rotation. Application to membrane systems

P. Fajer, D. Marsh, 1983 .

Myosin cleft closure by double electron–electron resonance and dipolar EPR

Clive R. Bagshaw, P. Fajer, A. Málnási-Csizmadia, 2007 .

Structure of the inhibitory region of troponin by site directed spin labeling electron paramagnetic resonance

P. Fajer, L. Brown, K. Sale, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Orientational changes of troponin C associated with thin filament activation.

P. Fajer, H. Li, 1994, Biochemistry.

The tropomyosin domain is flexible and disordered in reconstituted thin filaments.

D. Szczesna, P. Fajer, 1995, Biochemistry.

Method for the determination of myosin head orientation from EPR spectra.

P. Fajer, 1994, Biophysical journal.

Determination of spin-label orientation within the myosin head.

P. Fajer, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Effect of ADP on the orientation of spin-labeled myosin heads in muscle fibers: a high-resolution study with deuterated spin labels.

D. D. Thomas, P. Fajer, E. A. Fajer, 1990, Biochemistry.

Practical Pulsed Dipolar ESR (DEER)

P. Fajer, L. Brown, Louise J. Brown, 2007 .

Dynamics of Tropomyosin in Muscle Fibers as Monitored by Saturation Transfer EPR of Bi-Functional Probe

T. Kálai, K. Hideg, P. Fajer, 2011, PloS one.

Orientational disorder and motion of weakly attached cross-bridges.

D. D. Thomas, P. Fajer, E. A. Fajer, 1991, Biophysical journal.

Protein dynamics and monomer-monomer interactions in AntR activation by electron paramagnetic resonance and double electron-electron resonance.

T. Logan, P. Fajer, Timothy M Logan, 2007, Biochemistry.

Transient EPR of Spin-Labeled Proteins

P. Fajer, David D. Thomas, E. Ostap, 1993 .

Saturation transfer, continuous wave saturation, and saturation recovery electron spin resonance studies of chain-spin labeled phosphatidylcholines in the low temperature phases of dipalmitoyl phosphatidylcholine bilayers. Effects of rotational dynamics and spin-spin interactions.

P. Fajer, A. Watts, D. Marsh, 1992, Biophysical journal.

Myosin cleft movement and its coupling to actomyosin dissociation

Clive R. Bagshaw, P. Fajer, A. Málnási-Csizmadia, 2003, Nature Structural Biology.

Effects of AMPPNP on the orientation and rotational dynamics of spin-labeled muscle cross-bridges.

D. D. Thomas, P. Fajer, E. A. Fajer, 1988, Biophysical journal.

Myosin catalytic domain flexibility in MgADP.

K. Hideg, P. Fajer, D. Raucher, 1994, Biochemistry.

Full Atom Simulations of Spin Label Conformations.

Wei Yang, Mikolai Fajer, P. Fajer, 2015, Methods in enzymology.

Nonlinear-least-squares analysis of slow motional regime EPR spectra.

K. Khairy, D. Budil, P. Fajer, 2006, Journal of magnetic resonance.

Communication Nonlinear-least-squares analysis of slow motional regime EPR spectra q

K. Khairy, D. Budil, P. Fajer, 2006 .

Binding of MgtR, a Salmonella transmembrane regulatory peptide, to MgtC, a Mycobacterium tuberculosis virulence factor: a structural study.

Huan‐Xiang Zhou, P. Fajer, Alissa Myrick, 2014, Journal of molecular biology.

Myosin heads have a broad orientational distribution during isometric muscle contraction: time-resolved EPR studies using caged ATP.

D. D. Thomas, P. Fajer, E. A. Fajer, 1990, Proceedings of the National Academy of Sciences of the United States of America.

High-Resolution Detection of muscle Crossbridge Orientation by Electron Paramagnetic Resonance.

V. Barnett, D. D. Thomas, P. Fajer, 1986, Biophysical journal.

Broad disorder and the allosteric mechanism of myosin II regulation by phosphorylation

P. Fajer, P. Brewer, C. Cremo, 2011, Proceedings of the National Academy of Sciences.

Mapping electron paramagnetic resonance spin label conformations by the simulated scaling method.

P. Fajer, Hongzhi Li, M. Fajer, 2007, Journal of the American Chemical Society.

Nucleotide-induced flexibility change in neck linkers of dimeric kinesin as detected by distance Measurements using spin-labeling EPR.

P. Fajer, T. Arata, Likai Song, 2009, Journal of molecular biology.

Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods.

P. Fajer, B. Hambly, K. Sale, 2004, Biophysical journal.

Structural coupling of troponin C and actomyosin in muscle fibers.

P. Fajer, H. Li, 1998, Biochemistry.

The mobility of troponin C and troponin I in muscle

K. Hideg, P. Fajer, Hui‐Chun Li, 1997, Journal of molecular recognition : JMR.

Advantages of isotopic depletion of proteins for hydrogen/deuterium exchange experiments monitored by mass spectrometry.

P. Fajer, M. Emmett, A. Marshall, 2010, Analytical Chemistry.

Simulation of Slow Motion EPR Spectra with a General Hindering Potential Expanded in Spherical Harmonics

D. Budil, P. Fajer, Khaled Khairy, 2009 .

Myosin head orientation and mobility during isometric contraction: effects of osmotic compression.

P. Fajer, B. Adhikari, P. Fajer, 1996, Biophysical journal.

Conformational switching in muscle.

P. Fajer, 2004, Advances in experimental medicine and biology.

Advantages of isotopic depletion of proteins for hydrogen/deuterium exchange experiments monitored by mass spectrometry.

P. Fajer, M. Emmett, A. Marshall, 2010, Analytical chemistry.