D. Vance

发表

Inactivation of phosphatidylethanolamine N‐methyltransferase‐2 in aflatoxin‐induced liver cancer and partial reversion of the neoplastic phenotype by PEMT transfection of hepatoma cells

L. Tessitore, E. Sesca, D. Vance, 2000, International journal of cancer.

Oncogenic Ha-Ras Transformation Modulates the Transcription of the CTP:Phosphocholine Cytidylyltransferase α Gene via p42/44MAPK and Transcription Factor Sp3*

D. Vance, K. Waite, M. Bakovic, 2003, The Journal of Biological Chemistry.

Phosphorylation of Sp1 by Cyclin-dependent Kinase 2 Modulates the Role of Sp1 in CTP:Phosphocholine Cytidylyltransferase α Regulation during the S Phase of the Cell Cycle*

D. Vance, L. Schang, C. Banchio, 2004, Journal of Biological Chemistry.

Adipose tissue and lipid metabolism

D. Vance, J. Vance, 2022 .

Lipidomics is emerging.

M. Lagarde, D. Vance, M. Record, 2003, Biochimica et biophysica acta.

Phosphatidylcholine Homeostasis and Liver Failure*

D. Vance, Zhaoyu Li, L. Agellon, 2005, Journal of Biological Chemistry.

Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis

D. Vance, 2008, Current opinion in lipidology.

Effects of okadaic acid on the activities of two distinct phosphatidate phosphohydrolases in rat hepatocytes

D. Vance, G. Hatch, A. Gomez-Muñoz, 1992, FEBS letters.

Fatty acid desaturation and chain elongation in eukaryotes

D. Vance, J. Vance, 2003 .

Cholesterol in the year 2000.

D. Vance, H. van den Bosch, H. Bosch, 2000, Biochimica et biophysica acta.

Phosphatidylcholine Biosynthesis via CTP:Phosphocholine Cytidylyltransferase β2 Facilitates Neurite Outgrowth and Branching*

R. Campenot, D. Vance, J. Vance, 2008, Journal of Biological Chemistry.

Evidence that the Major Membrane Lipids, Except Cholesterol, Are Made in Axons of Cultured Rat Sympathetic Neurons

R. Campenot, D. Vance, J. Vance, 1994, Journal of neurochemistry.

Alkylphosphocholines inhibit choline uptake and phosphatidylcholine biosynthesis in rat sympathetic neurons and impair axonal extension.

R. Campenot, D. Vance, J. Vance, 1995, The Biochemical journal.

Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates.

D. Vance, R. Lehner, Wenhui Gao, 2004, Molecular biology of the cell.

Quantitative determination of the neutral glycosyl ceramides in human blood.

D. Vance, C. Sweeley, 1967, Journal of lipid research.

Additive Edman Degradation to sequence Small Peptides

D. Vance, D. Feingold, 1971, Nature.

Studies on the reaction of proteins and peptides with methyl isothiocyanate and identification of the methylthiohydantoins by gas-liquid chromatography.

D. Vance, D. Feingold, 1970, Analytical biochemistry.

Inhibition of Hepatic Phosphatidylcholine Synthesis by 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranoside Is Independent of AMP-activated Protein Kinase Activation*

J. Dyck, D. Vance, R. Jacobs, 2007, Journal of Biological Chemistry.

Tamoxifen induces triacylglycerol accumulation in the mouse liver by activation of fatty acid synthesis

D. Vance, R. Jacobs, L. Cole, 2010, Hepatology.

Physiological Regulation of Phospholipid Methylation Alters Plasma Homocysteine in Mice*

M. Brosnan, J. Brosnan, D. Vance, 2005, Journal of Biological Chemistry.

Metabolic Insights into Phospholipid Function Using Gene-targeted Mice*

D. Vance, J. Vance, 2005, Journal of Biological Chemistry.

A Rostrocaudal Muscular Dystrophy Caused by a Defect in Choline Kinase Beta, the First Enzyme in Phosphatidylcholine Biosynthesis*

W. Frankel, D. Vance, P. A. Wood, 2006, Journal of Biological Chemistry.

Niemann-Pick Type C1 deficiency in microglia does not cause neuron death in vitro.

R. Campenot, D. Vance, J. Vance, 2011, Biochimica et biophysica acta.

Regulation of triacylglycerol hydrolase expression by dietary fatty acids and peroxisomal proliferator-activated receptors.

V. Dolinsky, D. Vance, G. Hatch, 2003, Biochimica et biophysica acta.

Phospholipid biosynthesis in eukaryotes

D. Vance, J. Vance, 2008 .

Chapter 8 Phospholipid biosynthesis in eukaryotes

D. Vance, 2002 .

Roles for the methylation of phosphatidylethanolamine.

D. Vance, C. J. Walkey, C. Walkey, 1998, Current opinion in lipidology.

Chapter 6 - Glycerolipid biosynthesis in eukaryotes

D. Vance, 1996 .

Isolation and analysis of lipoproteins secreted by rat liver hepatocytes.

D. Vance, D. Steinberg, D. B. Weinstein, 1984, Biochimica et biophysica acta.

The synthesis and transport of lipids for axonal growth and nerve regeneration.

R. Campenot, D. Vance, J. Vance, 2000, Biochimica et biophysica acta.

The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes.

D. Vance, Z. Yao, Z. Yao, 1988, The Journal of biological chemistry.

Biosynthesis of membrane lipids in rat axons.

R. Campenot, D. Vance, J. Vance, 1991 .

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis.

D. Vance, T. Allen, M. Umeda, 2006, Cell metabolism.

A Role for Sp1 in Transcriptional Regulation of Phosphatidylethanolamine N-Methyltransferase in Liver and 3T3-L1 Adipocytes*

D. Vance, L. Cole, 2010, The Journal of Biological Chemistry.

Role of Histone Deacetylase in the Expression of CTP:Phosphocholine Cytidylyltransferase α*

D. Vance, C. Banchio, S. Lingrell, 2006, Journal of Biological Chemistry.

Hepatic uptake and metabolism of phosphatidylcholine associated with high density lipoproteins.

D. Vance, B. Trigatti, Z. Yao, 2009, Biochimica et biophysica acta.

The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion Published, JLR Papers in Press, June 26, 2007.

D. Vance, F. Kuipers, V. Bloks, 2007, Journal of Lipid Research.

Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.

D. Vance, A. Merrill, A. Gomez-Muñoz, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Lipid metabolism in plants

D. Vance, J. Vance, 2003 .

Hepatic CTP:Phosphocholine Cytidylyltransferase-α Is a Critical Predictor of Plasma High Density Lipoprotein and Very Low Density Lipoprotein*

G. Francis, D. Vance, R. Jacobs, 2008, Journal of Biological Chemistry.

Targeted Deletion of Hepatic CTP:phosphocholine Cytidylyltransferase α in Mice Decreases Plasma High Density and Very Low Density Lipoproteins*

D. Vance, C. Devlin, I. Tabas, 2004, Journal of Biological Chemistry.

Impaired Phosphatidylcholine Biosynthesis Reduces Atherosclerosis and Prevents Lipotoxic Cardiac Dysfunction in ApoE−/− Mice

V. Dolinsky, J. Dyck, D. Vance, 2011, Circulation research.

Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture and in Vivo*

D. Vance, G. Höfler, H. Köfeler, 2011, The Journal of Biological Chemistry.

Choline kinase and its function.

D. Vance, Gengshu Wu, 2010, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Triacylglycerol hydrolase: role in intracellular lipid metabolism

M. Alam, V. Dolinsky, D. Vance, 2004, Cellular and Molecular Life Sciences CMLS.

Is it time to reevaluate methyl balance in humans?

M. Brosnan, J. Brosnan, D. Vance, 2006, The American journal of clinical nutrition.

Characterization of the murine phosphatidylethanolamine N-methyltransferase-2 gene.

D. Vance, C. J. Walkey, L. Agellon, 1996, Journal of lipid research.

Conversion of Low Density Lipoprotein-associated Phosphatidylcholine to Triacylglycerol by Primary Hepatocytes*

D. Vance, B. Trigatti, R. Lehner, 2008, Journal of Biological Chemistry.

Lack of Phosphatidylethanolamine N-Methyltransferase Alters Plasma VLDL Phospholipids and Attenuates Atherosclerosis in Mice

G. Francis, J. Brosnan, D. Vance, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT[S]

D. Vance, J. Vance, R. Jacobs, 2015, Journal of Lipid Research.

Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity

J. Dyck, D. Vance, M. Young, 2007, Diabetes.

Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice.

D. Vance, R. Sher, G. Cox, 2009, Biochimica et biophysica acta.

Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase[S]

D. Vance, Z. Kassiri, R. Jacobs, 2017, Journal of Lipid Research.

Physiological roles of phosphatidylethanolamine N-methyltransferase.

D. Vance, 2013, Biochimica et biophysica acta.

Increased Hepatic CD 36 Expression Contributes to Dyslipidemia Associated with Diet-Induced Obesity

J. Dyck, D. Vance, M. Young, 2007 .

Impaired de Novo Choline Synthesis Explains Why Phosphatidylethanolamine N-Methyltransferase-deficient Mice Are Protected from Diet-induced Obesity*

J. Dyck, D. Vance, B. Kennedy, 2010, The Journal of Biological Chemistry.

Sp-1 Binds Promoter Elements That Are Regulated by Retinoblastoma and Regulate CTP:Phosphocholine Cytidylyltransferase-α Transcription*

D. Vance, C. Banchio, S. Lingrell, 2007, Journal of Biological Chemistry.

The FASEB Journal express article 10.1096/fj.02-0728fje. Published online July 18, 2003. Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion

D. Vance, R. Lehner, D. Gilham, 2022 .

Evidence that cyclic AMP-induced inhibition of phosphatidylcholine biosynthesis is caused by a decrease in cellular diacylglycerol levels in cultured rat hepatocytes.

D. Vance, A. K. Utal, H. Jamil, 1992, The Journal of biological chemistry.

A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling

D. Vance, S. Sipione, J. Curtis, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

ASMaseAlcohol LMP Lipotoxicity Apoptosis Necrosis Insulin resistance Fibrosis Membrane instability Impaired methylation and antioxidant defense Steatosis Liver injury Inflammation Fibrosis ASH / NASH Steatosis ER stress Autophagy

D. Vance, N. Kaplowitz, J. Fernandez-Checa, 2014 .

The assembly of lipids into lipoproteins during secretion

D. Vance, J. Vance, 1990, Experientia.

Reduction in VLDL, but not HDL, in plasma of rats deficient in choline.

D. Vance, Z. Yao, Z. Yao, 1990, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Biochemistry.of.Lipids,.Lipoproteins.and.Membranes,.4th.edition

D. Vance, J. Vance, 2002 .

Dynamics of lipoprotein transport in the human circulatory system

D. Vance, J. Vance, 2003 .

Pitfalls and problems in studies on the methylation of phosphatidylethanolamine.

D. Vance, F. Audubert, 1983, The Journal of biological chemistry.

A Role for Hepatic Scavenger Receptor Class B, Type I in Decreasing High Density Lipoprotein Levels in Mice That Lack Phosphatidylethanolamine N-Methyltransferase*

G. Francis, D. Vance, Julie C Robichaud, 2008, Journal of Biological Chemistry.

A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis.

D. Vance, Zhaoyu Li, L. Agellon, 2007, Biochimica et biophysica acta.

Fatty acids inhibit N-methylation of phosphatidylethanolamine in rat hepatocytes and liver microsomes.

D. Vance, S. Pelech, F. Audubert, 1984, Biochimica et biophysica acta.

The Membrane Lipid Phosphatidylcholine Is an Unexpected Source of Triacylglycerol in the Liver*

D. Vance, S. Lingrell, Jelske N. van der Veen, 2012, The Journal of Biological Chemistry.

Metabolism of molecular species of phosphatidylethanolamine and phosphatidylcholine in rat hepatocytes during prolonged inhibition of phosphatidylethanolamine N-methyltransferase.

D. Vance, N. Ridgway, R. W. Samborski, 1993, Journal of lipid research.

Evidence that remodeling of the fatty acids of phosphatidylcholine is regulated in isolated rat hepatocytes and involves both the sn-1 and sn-2 positions.

D. Vance, L. Tijburg, R. W. Samborski, 1991, Biochimica et biophysica acta.

Specificity of rat hepatic phosphatidylethanolamine N-methyltransferase for molecular species of diacyl phosphatidylethanolamine.

D. Vance, N. Ridgway, 1988, The Journal of biological chemistry.

Metabolism and function of bile acids Lui

D. Vance, J. Vance, 2003 .

Oxidation of fatty acids in eukaryotes

D. Vance, J. Vance, 2003 .

Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver.

D. Vance, N. Kaplowitz, M. Ookhtens, 2008, Alcoholism, clinical and experimental research.

Plasma Homocysteine Is Regulated by Phospholipid Methylation*

M. Brosnan, J. Brosnan, D. Vance, 2003, The Journal of Biological Chemistry.

A Gender-specific Role For Phosphatidylethanolamine N-Methyltransferase-derived Phosphatidylcholine in the Regulation of Plasma High Density and Very Low Density Lipoproteins in Mice*

D. Vance, Anna A. Noga, 2003, Journal of Biological Chemistry.

Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle.

D. Vance, J. Vance, R. Jacobs, 2016, Biochimica et biophysica acta.

Overview of lipoprotein secretion into the circulation

Jean, Vance, D. Vance, 2003 .

Fundamental research is the basis for understanding and treatment of many human diseases

D. Vance, 2006, FEBS letters.

Evaluation of possible mechanisms of phorbol ester stimulation of phosphatidylcholine synthesis in HeLa cells.

D. Vance, H. W. Cook, 1985, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.

Lipid requirements for the aggregation of CTP:phosphocholine cytidylyltransferase in rat liver cytosol.

D. Vance, P. Choy, S. Farren, 1979, Canadian journal of biochemistry.

Phorbol esters stimulate phosphatidylcholine biosynthesis by translocation of CTP:phosphocholine cytidylyltransferase from cytosol to microsomes.

D. Vance, S. Pelech, H. Paddon, 1984, Biochimica et biophysica acta.

Enzyme translocation in the regulation of phosphatidylcholine biosynthesis

D. Vance, S. Pelech, 1984 .

Subcellullar localization, developmental expression and characterization of a liver triacylglycerol hydrolase.

D. Vance, R. Lehner, Z. Cui, 1999, The Biochemical journal.

Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins.

R. Campenot, D. Vance, K. Ueda, 2011, Biochimica et biophysica acta.

Regulation of rat liver phosphatidylethanolamine N-methyltransferase by cytosolic factors. Examination of a role for reversible protein phosphorylation.

D. Vance, S. Pelech, F. Audubert, 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Specific pools of phospholipids are used for lipoprotein secretion by cultured rat hepatocytes.

D. Vance, J. Vance, 1986, The Journal of biological chemistry.

Heterologous expression, purification, and characterization of human triacylglycerol hydrolase.

D. Vance, R. Lehner, Mustafa Alam, 2002, Protein expression and purification.

Finding the balance: The role of S‐adenosylmethionine and phosphatidylcholine metabolism in development of nonalcoholic fatty liver disease

D. Vance, R. Jacobs, Jelske Veen, 2013, Hepatology.

Localization-independent Regulation of Homocysteine Secretion by Phosphatidylethanolamine N-Methyltransferase*

J. Brosnan, D. Vance, L. Agellon, 2005, Journal of Biological Chemistry.

Structure-function analysis of human triacylglycerol hydrolase by site-directed mutagenesis: identification of the catalytic triad and a glycosylation site.

D. Vance, R. Lehner, Mustafa Alam, 2002, Biochemistry.

Cloning and expression of a cDNA encoding a hepatic microsomal lipase that mobilizes stored triacylglycerol.

D. Vance, R. Lehner, 1999, The Biochemical journal.

Apolipoprotein B and triacylglycerol secretion in human triacylglycerol hydrolase transgenic mice Published, JLR Papers in Press, September 18, 2007.

D. Vance, R. Lehner, L. Agellon, 2007, Journal of Lipid Research.

Reduction of phosphatidylcholine turnover in a Nb 2 lymphoma cell line after prolactin treatment. A novel mechanism for control of phosphatidylcholine levels in cells.

D. Vance, K. Ko, H. W. Cook, 1986, The Journal of biological chemistry.

Diethylstilbestrol treatment increases the amount of choline kinase in rooster liver.

D. Vance, H. Paddon, C. Vigo, 1982, Biochimica et biophysica acta.

C/EBPα activates the transcription of triacylglycerol hydrolase in 3T3-L1 adipocytes

D. Vance, R. Lehner, Enhui Wei, 2005 .

Lipid modifications of proteins

D. Vance, J. Vance, 2003 .

Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis.

D. Vance, R. Jacobs, T. Chaba, 2011, Biochimica et biophysica acta.

Elevation of Ceramide within Distal Neurites Inhibits Neurite Growth in Cultured Rat Sympathetic Neurons*

R. Campenot, D. Vance, J. Vance, 1997, The Journal of Biological Chemistry.

Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse.

D. Vance, R. Sher, G. Cox, 2010, Biochimica et biophysica acta.

The ratio of phosphatidylcholine to phosphatidylethanolamine does not predict integrity of growing MT58 Chinese hamster ovary cells.

D. Vance, Lorissa J. Niebergall, 2012, Biochimica et biophysica acta.

Biochemical studies on the entry of sindbis virus into BHK-21 cells and the effect of NH4Cl.

D. Vance, P. Talbot, 1982, Virology.

Evidence that Sindbis virus infects BHK-21 cells via a lysosomal route.

D. Vance, P. Talbot, 1980, Canadian journal of biochemistry.

Choline cannot be replaced by propanolamine in mice.

D. Vance, Zhaoyu Li, 2007, Biochimica et biophysica acta.

Hepatic Phosphatidylethanolamine N-Methyltransferase, Unexpected Roles in Animal Biochemistry and Physiology*

D. Vance, Zhaoyu Li, R. Jacobs, 2007, Journal of Biological Chemistry.

Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic rats.

D. Vance, K. Nieman, R. Jacobs, 2006, The Journal of nutrition.

Trifluoperazine and chlorpromazine inhibit phosphatidylcholine biosynthesis and CTP:phosphocholine cytidylyltransferase in HeLa cells.

D. Vance, S. Pelech, 1984, Biochimica et biophysica acta.

Chapter 7 Phospholipid metabolism and cell signalling in eucaryotes

D. Vance, 1991 .

Does rat liver Golgi have the capacity to synthesize phospholipids for lipoprotein secretion?

D. Vance, J. Vance, 1988, The Journal of biological chemistry.

Impaired biosynthesis of phosphatidylcholine causes a decrease in the number of very low density lipoprotein particles in the Golgi but not in the endoplasmic reticulum of rat liver.

D. Vance, H. Verkade, D. Scraba, 1993, The Journal of biological chemistry.

Fatty acids promote translocation of CTP:phosphocholine cytidylyltransferase to the endoplasmic reticulum and stimulate rat hepatic phosphatidylcholine synthesis.

D. Vance, S. Pelech, D. Brindley, 1983, The Journal of biological chemistry.

Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone.

V. Dolinsky, D. Vance, D. Douglas, 2004, The Biochemical journal.

Control mechanisms in the synthesis of saturated fatty acids.

D. Vance, K. Bloch, 1977, Annual review of biochemistry.

Biochemistry of Lipids and Membranes

D. Vance, J. Vance, 1985 .

Mutation of F417 but not of L418 or L420 in the lipid binding domain decreases the activity of triacylglycerol hydrolase Published, JLR Papers in Press, November 10, 2005.

D. Vance, R. Lehner, Mustafa Alam, 2006, Journal of Lipid Research.

Implication of phosphatidylethanolamine N-methyltransferase in adipocyte differentiation.

D. Vance, A. Gomez-Muñoz, Jelske N. van der Veen, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene.

D. Vance, L. Agellon, D. Shields, 2001, Biochimica et biophysica acta.

Choline Supplementation Promotes Hepatic Insulin Resistance in Phosphatidylethanolamine N-Methyltransferase-deficient Mice via Increased Glucagon Action*

D. Vance, G. Lopaschuk, Liang Li, 2012, The Journal of Biological Chemistry.

Purification and properties of the fatty acid synthetase from Mycobacterium phlei.

D. Vance, K. Bloch, O. Mitsuhashi, 1973, The Journal of biological chemistry.

Binding of CTP: phosphocholine cytidylyltransferase to large unilamellar vesicles.

D. Vance, R. Cornell, 1987, Biochimica et biophysica acta.

Choline kinase and ethanolamine kinase are separate, soluble enzymes in rat liver.

P. Brophy, D. Vance, P. Choy, 1977, European journal of biochemistry.

Sphingolipid Biosynthesis de Novo by Rat Hepatocytes in Culture.

D. Vance, T. Vales, M. Nikolova-Karakashian, 1995, The Journal of Biological Chemistry.

Stimulation of sphingomyelin biosynthesis by brefeldin A and sphingomyelin breakdown by okadaic acid treatment of rat hepatocytes.

D. Vance, G. Hatch, Grant M. Hatch, 1992, The Journal of biological chemistry.

Phosphatidylcholine Metabolism

D. Vance, 2020 .

Neuronal models for studying lipid metabolism and transport.

R. Campenot, D. Vance, H. Hayashi, 2005, Methods.

Involvement of the lysosome in the catabolism of intracellular lysophosphatidylcholine and evidence for distinct pools of lysophosphatidylcholine.

D. Vance, G. Hatch, A. Oskin, 1993, Journal of lipid research.

Diacylglycerol signals the translocation of CTP:choline-phosphate cytidylyltransferase in HeLa cells treated with 12-O-tetradecanoylphorbol-13-acetate.

D. Vance, A. K. Utal, H. Jamil, 1991, The Journal of biological chemistry.

Nascent VLDL phospholipid composition is altered when phosphatidylcholine biosynthesis is inhibited: evidence for a novel mechanism that regulates VLDL secretion.

D. Vance, D. G. Fast, 1995, Biochimica et biophysica acta.

Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.

D. Vance, A. Gomez-Muñoz, M. Hermansson, 2015, Biochimica et biophysica acta.

The role of phosphatidylcholine biosynthesis in the secretion of lipoproteins from hepatocytes.

D. Vance, J. Vance, 1985, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.

Sphingolipids : metabolism and cell signaling

D. Vance, J. Vance, 2022 .

Comparison of albumin-mediated release of lysophosphatidylcholine and lysophosphatidylethanolamine from cultured rat hepatocytes.

D. Vance, B. S. Robinson, D. Baisted, 1989, The Biochemical journal.

Transcription of the CTP:Phosphocholine Cytidylyltransferase α Gene Is Enhanced during the S Phase of the Cell Cycle*

D. Vance, L. Golfman, M. Bakovic, 2001, The Journal of Biological Chemistry.

Evidence that the rate of phosphatidylcholine catabolism is regulated in cultured rat hepatocytes.

D. Vance, T. Nishimaki-Mogami, L. Tijburg, 1991, Biochimica et biophysica acta.

Insights into the requirement of phosphatidylcholine synthesis for liver function in mice Published, JLR Papers in Press, July 1, 2003. DOI 10.1194/jlr.M300226-JLR200

D. Vance, Anna A. Noga, 2003, Journal of Lipid Research.

The effect of colchicine and dibucaine on the morphogenesis of Semliki Forest virus.

D. Vance, C. Richardson, 1978, The Journal of biological chemistry.

Lipoprotein assembly and secretion by hepatocytes.

D. Vance, J. Vance, Jean E. Vance, 1990, Annual review of nutrition.

The unique acyl chain specificity of biliary phosphatidylcholines in mice is independent of their biosynthetic origin in the liver

D. Vance, C. J. Walkey, F. Kuipers, 1999, Hepatology.

Enhanced Expression and Activation of CTP:Phosphocholine Cytidylyltransferase β2 during Neurite Outgrowth*

R. Campenot, D. Vance, K. Waite, 2003, Journal of Biological Chemistry.

Phosphatidylcholine metabolism and choline kinase in human osteoblasts.

D. Vance, M. Hermansson, Gengshu Wu, 2014, Biochimica et biophysica acta.

From masochistic enzymology to mechanistic physiology and disease

D. Vance, 2017, The Journal of Biological Chemistry.

Phosphatidylcholine biosynthesis: unexpected player in metabolic disease

D. Vance, 2008 .

Early Embryonic Lethality Caused by Disruption of the Gene for Choline Kinase α, the First Enzyme in Phosphatidylcholine Biosynthesis*

S. Young, D. Vance, Gengshu Wu, 2007, Journal of Biological Chemistry.

Choline Redistribution during Adaptation to Choline Deprivation*

D. Vance, Zhaoyu Li, L. Agellon, 2007, Journal of Biological Chemistry.

An Unexpected Requirement for PhosphatidylethanolamineN-Methyltransferase in the Secretion of Very Low Density Lipoproteins*

D. Vance, Yang Zhao, Anna A. Noga, 2002, The Journal of Biological Chemistry.

Choline deficiency-induced liver damage is reversible in Pemt(-/-) mice.

D. Vance, K. Waite, Nora R. Cabilio, 2002, The Journal of nutrition.

Obituary: Konrad E. Bloch (1912–2000)

D. Vance, H. Goldfine, 2001, Nature.

Chemical cross-linking of proteins of Semliki Forest virus: virus particles and plasma membranes from BHK-21 cells treated with colchicine or dibucaine

D. Vance, C. Richardson, 1978, Journal of virology.

Cloning and expression of a cDNA encoding a hepatic microsomal lipase that mobilizes stored triacylglycerol.

D. Vance, R. Lehner, 1999, The Biochemical journal.

Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice

D. Vance, G. Lopaschuk, R. Jacobs, 2012, Journal of obesity.

Activation of CTP:Phosphocholine Cytidylyltransferase α Expression during the S Phase of the Cell Cycle Is Mediated by the Transcription Factor Sp1*

D. Vance, L. Schang, C. Banchio, 2003, Journal of Biological Chemistry.

Conversion of phosphatidylethanolamine to phosphatidylcholine in rat liver. Partial purification and characterization of the enzymatic activities.

D. Vance, W. Schneider, 1979, The Journal of biological chemistry.

Control of Phosphatidylcholine Biosynthesis and Its Role in Lipoprotein Assembly

D. Vance, H. Verkade, S. Lingrell, 1992 .

The biosynthesis of phosphatidylcholine by methylation of phosphatidylethanolamine derived from ethanolamine is not required for lipoprotein secretion by cultured rat hepatocytes.

D. Vance, J. Vance, T. M. Nguyen, 1986, Biochimica et biophysica acta.

Albumin stimulates the release of lysophosphatidylcholine from cultured rat hepatocytes.

D. Vance, B. S. Robinson, D. Baisted, 1988, The Biochemical journal.

Henk van den Bosch: chemist and biochemist.

D. Vance, F. Spener, 2004, Biochimica et biophysica acta.

Kinetic mechanism of phosphatidylethanolamine N-methyltransferase.

D. Vance, N. Ridgway, 1988, The Journal of biological chemistry.

Phospholipid methylation in mammals: from biochemistry to physiological function.

D. Vance, 2014, Biochimica et biophysica acta.

Quantitative determination of tritium in metals and oxides

D. Vance, M. Smith, G. Waterbury, 1979 .

The methylation of phosphatidylethanolamine.

D. Vance, N. Ridgway, D E Vance, 1988, Progress in lipid research.

[68] CTP: Phosphocholine cytidylyltransferase from rat liver: EC 2.7.7.15 CTP: Phosphocholine cytidylyltransferase

D. Vance, P. Choy, S. Pelech, 1981 .

Biochemistry of Lipids, Lipoproteins and Membranes

D. Vance, J. Vance, 2002 .

Inhibition of fatty acid synthetases by the antibiotic cerulenin.

S. Ōmura, D. Vance, K. Bloch, 1972, Biochemical and biophysical research communications.

How is phosphatidylcholine biosynthesis regulated

D. Vance, P. Choy, 1979 .

Regulation of phosphatidylcholine biosynthesis.

D. Vance, S. Pelech, D E Vance, 1984, Biochimica et biophysica acta.

Prolonged effects of cyclic AMP analogues of phosphatidylcholine biosynthesis in cultured rat hepatocytes.

D. Vance, S. Pelech, P. Pritchard, 1982, Biochimica et biophysica acta.

cAMP analogues inhibit phosphatidylcholine biosynthesis in cultured rat hepatocytes.

D. Vance, S. Pelech, P. Pritchard, 1981, The Journal of biological chemistry.

Inhibition of phosphatidylethanolamine N-methylation by 3-deazaadenosine stimulates the synthesis of phosphatidylcholine via the CDP-choline pathway.

P. Chiang, D. Vance, G. Cantoni, 1982, The Journal of biological chemistry.

The possible functional significance of phosphatidylethanolamine methylation

D. Vance, B. Kruijff, 1980, Nature.

Poliovirus increases phosphatidylcholine biosynthesis in HeLa cells by stimulation of the rate-limiting reaction catalyzed by CTP: phosphocholine cytidylyltransferase.

D. Vance, H. Paddon, E. Trip, 1980, The Journal of biological chemistry.

Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion.

D. Vance, G. Hatch, D. Wilton, 1993, The Biochemical journal.

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

T. Shioda, Fajun Yang, J. Watts, 2011, Cell.

Evidence that only newly made phosphatidylethanolamine is methylated to phosphatidylcholine and that phosphatidylethanolamine is not significantly deacylated-reacylated in rat hepatocytes.

D. Vance, N. Ridgway, R. W. Samborski, 1990, The Journal of biological chemistry.

Konrad Bloch--a pioneer in cholesterol and fatty acid biosynthesis.

D. Vance, H. Goldfine, 2002, Biochemical and biophysical research communications.

Compartmentalization of choline and acetylcholine metabolism in cultured sympathetic neurons.

R. Campenot, D. Vance, J. Vance, 2001, Journal of Biochemistry (Tokyo).

Methyl balance and transmethylation fluxes in humans.

Conrad Wagner, M. Brosnan, J. Brosnan, 2007, The American journal of clinical nutrition.

Phosphatidylethanolamine N-methyltransferase from liver.

D. Vance, Z. Cui, C. Walkey, 1997, Biochimica et biophysica acta.

Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase.

Robert V Farese, M. Mann, M. Hilger, 2011, Cell metabolism.

The synthesis and hydrolysis of long-chain fatty acyl-coenzyme A thioesters by soluble and microsomal fractions from the brain of the developing rat.

P. Brophy, D. Vance, 1976, The Biochemical journal.

Purification and characterization of CTP: cholinephosphate cytidylytransferase from rat liver cytosol.

D. Vance, P. Choy, P. Lim, 1977, The Journal of biological chemistry.

Copurification of choline kinase and ethanolamine kinase from rat liver by affinity chromatography

P. Brophy, D. Vance, 1976, FEBS letters.

Inhibition of 3-sn-phosphatidylcholine biosynthesis in baby-hamster kidney-21 cells infected with Semliki Forest virus.

D. Vance, D. Burke, 1974, European journal of biochemistry.

Evidence that the enzymes involved in the methylation of phosphatidylethanolamine are on the external side of the microsomal vesicles.

D. Vance, F. Audubert, 1984, Biochimica et biophysica acta.

Asymmetry of phospholipid biosynthesis

D. Vance, P. Choy, S. Farren, 1977, Nature.

Phosphatidylethanolamine derived from phosphatidylserine is deacylated and reacylated in rat hepatocytes.

D. Vance, R. W. Samborski, 1993, Biochimica et biophysica acta.

A deazaadenosine‐insensitive methylation of phosphatidylethanolamine is involved in lipoprotein secretion

D. Vance, J. Vance, 1986, FEBS letters.

Concentrations of glycosyl ceramides in plasma and red cells in Fabry's disease, a glycolipid lipidosis.

D. Vance, C. Sweeley, W. Krivit, 1969, Journal of lipid research.

Phospholipid biosynthesis in mammalian cells.

D. Vance, J. Vance, 2004, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Effect of choline deficiency on the enzymes that synthesize phosphatidylcholine and phosphatidylethanolamine in rat liver.

D. Vance, W. Schneider, 1978, European Journal of Biochemistry.

Characterization of lipid and lipoprotein metabolism in primary human hepatocytes.

D. Vance, N. Kneteman, D. Douglas, 2013, Biochimica et biophysica acta.

Impaired phosphatidylcholine biosynthesis does not attenuate liver regeneration after 70% partial hepatectomy in hepatic CTP:phosphocholine cytidylyltransferase-α deficient mice.

D. Vance, R. Jacobs, Lin‐Fu Zhu, 2012, Canadian journal of physiology and pharmacology.

Phosphatidylcholine and choline homeostasis.

D. Vance, Zhaoyu Li, 2008, Journal of lipid research.

A Choline-deficient Diet in Mice Inhibits neither the CDP-choline Pathway for Phosphatidylcholine Synthesis in Hepatocytes nor Apolipoprotein B Secretion*

D. Vance, J. Vance, A. Kulinski, 2004, Journal of Biological Chemistry.

Expression of phosphatidylethanolamine N-methyltransferase in Yoshida ascites hepatoma cells and the livers of host rats.

L. Tessitore, E. Sesca, D. Vance, 1999, Carcinogenesis.

Inverse correlation between expression of phosphatidylethanolamine N-methyltransferase-2 and growth rate of perinatal rat livers.

D. Vance, Z. Cui, Y. Shen, 1997, Biochimica et biophysica acta.

Induction of hepatocyte proliferation after partial hepatectomy is accompanied by a markedly reduced expression of phosphatidylethanolamine N-methyltransferase-2.

L. Tessitore, D. Vance, M. Houweling, 1997, Biochimica et biophysica acta.

Requirement of phosphatidylcholine for normal progression through the cell cycle in C3H/10T1/2 fibroblasts.

D. Vance, F. Tercé, H. Brun, 1994, Journal of lipid research.

The Enzymes of Phosphatidylcholine Biosynthesis

D. Vance, N. Ridgway, J. Sanghera, 1986 .

Diethylstilbestrol treatment modulates the enzymatic activities of phosphatidylcholine biosynthesis in rooster liver.

D. Vance, P. Pritchard, H. Paddon, 1981, Biochimica et biophysica acta.

[69] Conversion of phosphatidylethanolamine to phosphatidylcholine: EC 2.1.1.17 S-Adenosyl-l-methionine : phosphatidylethanolamine N-methyltransferase

D. Vance, W. Schneider, 1981 .

Immunological studies on CTP:phosphocholine cytidylyltransferase from the livers of normal and choline-deficient rats.

D. Vance, W. Schneider, P. Choy, 1978, European journal of biochemistry.

The relationship between cholinephosphate phosphatase (alkaline phosphatase) and phosphatidylcholine biosynthesis in HeLa cells.

D. Vance, H. Paddon, Dennis E. Vance, 1977, Biochimica et biophysica acta.

Inhibition of phosphatidylethanolamine biosynthesis in baby hamster kidney-21 cells infected with Semliki Forest virus.

D. Vance, R. Dahlke, 1975, Canadian journal of biochemistry.

Choline metabolism and phosphatidylcholine biosynthesis in cultured rat hepatocytes.

D. Vance, P. Pritchard, 1981, The Biochemical journal.

Expression of Phosphatidylethanolamine N-Methyltransferase in Human Hepatocellular Carcinomas

M. Papotti, L. Tessitore, D. Vance, 2003, Oncology.

Transient inactivation of phosphatidylethanolamine N-methyltransferase-2 and activation of cytidine triphosphate: phosphocholine cytidylyltransferase during non-neoplastic liver growth.

L. Tessitore, D. Vance, Z. Cui, 1997, The Biochemical journal.

The Epigenetic Drug 5-Azacytidine Interferes with Cholesterol and Lipid Metabolism*

D. Vance, G. Hatch, G. Mayer, 2014, The Journal of Biological Chemistry.

Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-deficient mice.

Ariel D. Quiroga, D. Vance, R. Lehner, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice[S]

J. Degen, K. Willecke, D. Vance, 2015, Journal of Lipid Research.

Missense Mutations in APOB within the βα1 Domain of Human APOB-100 Result in Impaired Secretion of ApoB and ApoB-containing Lipoproteins in Familial Hypobetalipoproteinemia*

R. Hegele, D. Vance, R. McLeod, 2007, Journal of Biological Chemistry.

Identification of nuclear localization and nuclear export signals in Ets2, and the transcriptional regulation of Ets2 and CTP:phosphocholine cytidylyltransferase alpha in tetradecanoyl-13-acetate or macrophage-colony stimulating factor stimulated RAW264 cells.

D. Vance, K. Takagishi, H. Sugimoto, 2009, Biochimica et biophysica acta.

Transcriptional regulation of phosphatidylcholine biosynthesis.

D. Vance, C. Banchio, H. Sugimoto, 2008, Progress in lipid research.

Identification of Ets-1 as an Important Transcriptional Activator of CTP: Phosphocholine Cytidylyltransferase α in COS-7 Cells and Co-activation with Transcriptional Enhancer Factor-4*

D. Vance, M. Bakovic, H. Sugimoto, 2003, Journal of Biological Chemistry.

Sp1 Is a Co-activator with Ets-1, and Net Is an Important Repressor of the Transcription of CTP:Phosphocholine Cytidylyltransferase α*

D. Vance, M. Satou, H. Sugimoto, 2005, Journal of Biological Chemistry.

Identification of Transcriptional Enhancer Factor-4 as a Transcriptional Modulator of CTP:Phosphocholine Cytidylyltransferase α*

D. Vance, M. Bakovic, H. Sugimoto, 2001, The Journal of Biological Chemistry.

Functional significance of Sp1, Sp2, and Sp3 transcription factors in regulation of the murine CTP:phosphocholine cytidylyltransferase alpha promoter.

D. Vance, K. Waite, M. Bakovic, 2000, Journal of lipid research.

Transcriptional activation of the murine CTP:phosphocholine cytidylyltransferase gene (Ctpct): combined action of upstream stimulatory and inhibitory cis-acting elements.

D. Vance, K. Waite, M. Bakovic, 1999, Biochimica et biophysica acta.

Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress.

D. Vance, J. Vance, A. Thiesen, 2015, Biochimica et biophysica acta.

Lysophosphatidylcholine metabolism and lipoprotein secretion by cultured rat hepatocytes deficient in choline.

D. Vance, B. S. Robinson, Z. Yao, 1989, The Biochemical journal.

Phosphatidylcholine biosynthesis and lipoprotein metabolism.

D. Vance, J. Vance, L. Cole, 2012, Biochimica et biophysica acta.

The supply of both CDP-choline and diacylglycerol can regulate the rate of phosphatidylcholine synthesis in HeLa cells.

D. Vance, R. Cornell, P. Lim, 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.

CTP: phosphocholine cytidylyltransferase is both a nuclear and cytoplasmic protein in primary hepatocytes.

D. Vance, C. D. Anfuso, M. Houweling, 1996, European journal of cell biology.

Translocation of CTP: phosphocholine cytidylyltransferase from cytosol to membranes in HeLa cells: stimulation by fatty acid, fatty alcohol, mono- and diacylglycerol.

D. Vance, R. Cornell, 1987, Biochimica et biophysica acta.

Boehringer Mannheim Award lecture. Phosphatidylcholine metabolism: masochistic enzymology, metabolic regulation, and lipoprotein assembly.

D. Vance, 1990, Biochemistry and cell biology = Biochimie et biologie cellulaire.

The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.

D. Vance, J. Vance, R. Jacobs, 2017, Biochimica et biophysica acta. Biomembranes.

Hepatic ratio of phosphatidylcholine to phosphatidylethanolamine predicts survival after partial hepatectomy in mice

D. Vance, T. Chaba, Lin‐Fu Zhu, 2012, Hepatology.

Elongation of fatty acids by microsomal fractions from the brain of the developing rat.

P. Brophy, D. Vance, 1975, The Biochemical journal.

Dephosphorylation of CTP-phosphocholine cytidylyltransferase is not required for binding to membranes.

D. Vance, G. Hatch, M. Houweling, 1994, The Journal of biological chemistry.

On the mechanism of the okadaic acid-induced inhibition of phosphatidylcholine biosynthesis in isolated rat hepatocytes.

D. Vance, G. Hatch, A. K. Utal, 1992, The Journal of biological chemistry.

Choline deficiency causes translocation of CTP:phosphocholine cytidylyltransferase from cytosol to endoplasmic reticulum in rat liver.

D. Vance, Z. Yao, H. Jamil, 1990, The Journal of biological chemistry.

Membrane-bound CTP:phosphocholine cytidylyltransferase regulates the rate of phosphatidylcholine synthesis in HeLa cells treated with unsaturated fatty acids.

D. Vance, S. Pelech, H. Paddon, 1984, Biochimica et biophysica acta.

Involvement of CTP:phosphocholine cytidylyltransferase-β2 in axonal phosphatidylcholine synthesis and branching of neurons.

J. Straková, R. Campenot, D. Vance, 2011, Biochimica et biophysica acta.

Evidence that binding of CTP:phosphocholine cytidylyltransferase to membranes in rat hepatocytes is modulated by the ratio of bilayer- to non-bilayer-forming lipids.

D. Vance, G. Hatch, H. Jamil, 1993, The Biochemical journal.

A Genetic Defect in Phosphatidylcholine Biosynthesis Triggers Apoptosis in Chinese Hamster Ovary Cells*

D. Vance, M. Record, M. Houweling, 1996, The Journal of Biological Chemistry.

Phosphatidylcholine biosynthesis is required for secretion of truncated apolipoprotein Bs from McArdle RH7777 cells only when a neutral lipid core is formed.

D. Vance, Z. Yao, S. Lingrell, 1997, Journal of lipid research.

Control of Phosphatidylcholine Metabolism

D. Vance, G. Hatch, L. Tijburg, 1993 .

Substrate specificity of CTP:phosphocholine cytidylyltransferase.

D. Vance, H. Jamil, 1991, Biochimica et biophysica acta.

The protein phosphatase inhibitor, okadaic acid, inhibits phosphatidylcholine biosynthesis in isolated rat hepatocytes.

D. Vance, G. Hatch, Y. Tsukitani, 1991, Biochimica et biophysica acta.

Stimulation of CTP: phosphocholine cytidylyltransferase and phosphatidylcholine synthesis by incubation of rat hepatocytes with phospholipase A2.

D. Vance, J. Sanghera, 1990, Biochimica et biophysica acta.

Stimulation of CTP: phosphocholine cytidylyltransferase and phosphatidylcholine synthesis by calcium in rat hepatocytes.

D. Vance, J. Sanghera, 1989, Biochimica et biophysica acta.

Signal transduction via phosphatidylcholine cycles

Dennis E. Vance, D. Vance, S. Pelech, 1989 .

Control of Lecithin Metabolism

D. Vance, 1987 .

Lipid requirements for activation of CTP: phosphocholine cytidylyltransferase from rat liver.

D. Vance, P. Choy, 1978, The Journal of biological chemistry.

CTP:phosphocholine cytidylyltransferase is a substrate for cAMP-dependent protein kinase in vitro.

D. Vance, J. Sanghera, 1989, The Journal of biological chemistry.

Stimulation of hepatic phosphatidylcholine biosynthesis in rats fed a high cholesterol and cholate diet correlates with translocation of CTP: phosphocholine cytidylyltransferase from cytosol to microsomes.

D. Vance, P. Pritchard, H. Paddon, 1983, Biochimica et biophysica acta.

Regulation of rat liver cytosolic CTP: phosphocholine cytidylyltransferase by phosphorylation and dephosphorylation.

D. Vance, S. Pelech, 1982, The Journal of biological chemistry.

Expression of Phosphatidylethanolamine N-Methyltransferase-2 Cannot Compensate for an Impaired CDP-choline Pathway in Mutant Chinese Hamster Ovary Cells (*)

D. Vance, M. Houweling, Z. Cui, 1995, The Journal of Biological Chemistry.

William D. Ehmann, radioanalytical chemist and radiochemistry educator

D. Vance, S. Yates, 1997 .

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

V. Dolinsky, P. Light, J. Dyck, 2010, Diabetes.

Semliki Forest virus does not inhibit phosphatidylcholine biosynthesis in BHK-21 cells.

D. Vance, E. Trip, F. W. Whitehead, 1981, Canadian journal of biochemistry.

Fatty acid and phospholipid metabolism in prokaryotes

D. Vance, J. Vance, 2003 .

The cloning and expression of a murine triacylglycerol hydrolase cDNA and the structure of its corresponding gene.

V. Dolinsky, D. Vance, R. Lehner, 2001, Biochimica et biophysica acta.

The Concentration of Phosphatidylethanolamine in Mitochondria Can Modulate ATP Production and Glucose Metabolism in Mice

D. Vance, R. Jacobs, S. Lingrell, 2014, Diabetes.

Biochemical and Evolutionary Significance of Phospholipid Methylation*

D. Vance, Liqing Yu, L. Agellon, 1998, The Journal of Biological Chemistry.

Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase.

R. Bronson, D. Vance, L. Agellon, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Expression of Phosphatidylethanolamine N-Methyltransferase-2 Is Markedly Enhanced in Long Term Choline-deficient Rats (*)

D. Vance, Z. Cui, 1996, The Journal of Biological Chemistry.

Purification of phosphatidylethanolamine N-methyltransferase from rat liver.

D. Vance, N. Ridgway, 1987, The Journal of biological chemistry.

Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver.

D. Vance, J. Vance, D. Voelker, 1993, The Journal of biological chemistry.

Protection of Neurons from Apoptosis by Apolipoprotein E-containing Lipoproteins Does Not Require Lipoprotein Uptake and Involves Activation of Phospholipase Cγ1 and Inhibition of Calcineurin*

R. Campenot, D. Vance, H. Hayashi, 2009, The Journal of Biological Chemistry.

The role of phosphatidylethanolamine methyltransferase in a mouse model of intrahepatic cholestasis.

D. Vance, Zhaoyu Li, L. Agellon, 2011, Biochimica et biophysica acta.

Ceramide Inhibits Axonal Growth and Nerve Growth Factor Uptake without Compromising the Viability of Sympathetic Neurons*

R. Campenot, D. Vance, J. Vance, 2001, The Journal of Biological Chemistry.

Phosphatidylethanolamine levels and regulation of phosphatidylethanolamine N-methyltransferase.

D. Vance, N. Ridgway, Z. Yao, 1989, The Journal of biological chemistry.

Principles of Biochemistry

Dennis E. Vance, Geoffrey L. Zubay, William W. Parson, 1995 .

Glial Lipoproteins Stimulate Axon Growth of Central Nervous System Neurons in Compartmented Cultures*

R. Campenot, D. Vance, H. Hayashi, 2004, Journal of Biological Chemistry.

Novel Role for Matrix Metalloproteinase 9 in Modulation of Cholesterol Metabolism

D. Vance, G. Lambeau, J. Vance, 2016, Journal of the American Heart Association.

Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann–Pick C1‐deficient neurons

R. Campenot, D. Vance, J. Vance, 2002, Journal of neurochemistry.

Apolipoprotein E-Containing Lipoproteins Protect Neurons from Apoptosis via a Signaling Pathway Involving Low-Density Lipoprotein Receptor-Related Protein-1

R. Campenot, D. Vance, H. Hayashi, 2007, The Journal of Neuroscience.

Trafficking of Cholesterol from Cell Bodies to Distal Axons in Niemann Pick C1-deficient Neurons*

R. Campenot, D. Vance, J. Vance, 2003, The Journal of Biological Chemistry.

Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase.

D. Vance, C. Holmes, R. Lehner, 2005, Biochimica et biophysica acta.

The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals Published, JLR Papers in Press, December 10, 2005.

R. Campenot, D. Vance, J. Vance, 2006, Journal of Lipid Research.

Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice.

G. Francis, R. Campenot, D. Vance, 2005, The Biochemical journal.

Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways.

D. Vance, N. Kaplowitz, J. Fernandez-Checa, 2015, Journal of hepatology.

Methylation of Phosphatidylethanolamine: Enzyme Characterization, Regulation and Physiological Function

D. Vance, N. Ridgway, 1986 .

A rapid method for the determination of CTP and phosphocholine in rat liver and baby hamster kidney 21 cells.

D. Vance, P. Choy, F. W. Whitehead, 1978, Canadian journal of biochemistry.

Lipid molecular timeline profiling reveals diurnal crosstalk between the liver and circulation.

Christer S. Ejsing, Rolf Fagerberg, D. Vance, 2021, Cell reports.

Role of Lipoproteins in the Delivery of Lipids to Axons during Axonal Regeneration*

R. Campenot, D. Vance, J. Vance, 1997, The Journal of Biological Chemistry.

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q

D. James, D. Vance, J. Ho, 2021, Redox biology.

Membrane Topography of Human Phosphatidylethanolamine N-Methyltransferase*

D. Vance, R. Lehner, L. Agellon, 2003, The Journal of Biological Chemistry.

CPT-cAMP and okadaic acid enhance phosphatidylcholine catabolism in choline-deficient rat hepatocytes.

D. Vance, G. Hatch, 1991, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Analogues of cyclic AMP inhibit phosphatidylethanolamine N-methylation by cultured rat hepatocytes.

D. Vance, S. Pelech, P. Pritchard, 1981, Biochimica et biophysica acta.

Feedback regulation of CTP:phosphocholine cytidylyltransferase translocation between cytosol and endoplasmic reticulum by phosphatidylcholine.

D. Vance, Z. Yao, H. Jamil, 1990, The Journal of biological chemistry.

Effect of NaF and okadaic acid on the subcellular distribution of CTP: phosphocholine cytidylyltransferase activity in rat liver.

D. Vance, G. Hatch, Y. Tsukitani, 1990, Biochimica et biophysica acta.

Validation of NAA data for a background soils characterization project

D. Vance, L. Robinson, 1995 .

Choline kinase beta is required for normal endochondral bone formation.

D. Vance, M. Hermansson, M. Doschak, 2014, Biochimica et biophysica acta.

Methods for the study of lipid metabolism in neurons.

R. Campenot, D. Vance, H. Hayashi, 2004, Analytical biochemistry.

Role of axons in membrane phospholipid synthesis in rat sympathetic neurons

R. Campenot, D. Vance, J. Vance, 1995, Neurobiology of Aging.

Axonal synthesis of phosphatidylcholine is required for normal axonal growth in rat sympathetic neurons

R. Campenot, D. Vance, J. Vance, 1995, The Journal of cell biology.

Neptunium determination by inductively coupled plasma mass spectrometry (ICP-MS)

D. Vance, T. J. Oatts, D. K. Mann, 1998 .

Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.

B. Chait, D. Vance, J. Breslow, 2003, Journal of lipid research.

Uptake of Lipoproteins for Axonal Growth of Sympathetic Neurons*

R. Campenot, R. S. Kiss, D. Vance, 2000, The Journal of Biological Chemistry.

Induction of choline kinase alpha by carbon tetrachloride (CCl4) occurs via increased binding of c-jun to an AP-1 element.

D. Vance, H. Sugimoto, C. Aoyama, 2007, Biochimica et biophysica acta.

Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes.

D. Vance, Q. Xiao, H. Pan, 2005, Diabetes.

Molecular Dissection of the S-Adenosylmethionine-binding Site of Phosphatidylethanolamine N-Methyltransferase*

D. Vance, L. Agellon, D. Shields, 2003, Journal of Biological Chemistry.

Activities of the phosphatidylcholine biosynthetic enzymes in rat liver during development.

D. Vance, S. Pelech, E. Power, 1983, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.

Phosphatidylcholine metabolism in neonatal mouse calvaria.

D. Vance, P. Stern, 1987, The Biochemical journal.

Corrigendum to Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice

D. Vance, R. Sher, G. Cox, 2010 .

Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High‐Fat Diet

D. Vance, F. Kuipers, Hiromi Ando, 2019, Hepatology communications.

Diminished expression of phosphatidylethanolamine N-methyltransferase 2 during hepatocarcinogenesis.

L. Tessitore, D. Vance, I. Dianzani, 1999, The Biochemical journal.

Expression of phosphatidylethanolamine N-methyltransferase-2 in McArdle-RH7777 hepatoma cells inhibits the CDP-choline pathway for phosphatidylcholine biosynthesis via decreased gene expression of CTP:phosphocholine cytidylyltransferase.

D. Vance, M. Houweling, Z. Cui, 1995, The Biochemical journal.

Suppression of rat hepatoma cell growth by expression of phosphatidylethanolamine N-methyltransferase-2.

D. Vance, M. Houweling, Z. Cui, 1994, The Journal of biological chemistry.

Phosphatidylcholine metabolism in rat liver after partial hepatectomy. Evidence for increased activity and amount of CTP:phosphocholine cytidylyltransferase.

D. Vance, M. Houweling, W. J. Vaartjes, 1991, The Biochemical journal.

Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes.

D. Vance, Z. Yao, D. E. Vance, 1989, The Journal of biological chemistry.

Fatty acids reverse the cyclic AMP inhibition of triacylglycerol and phosphatidylcholine synthesis in rat hepatocytes.

D. Vance, S. Pelech, D. Brindley, 1983, The Biochemical journal.

Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism.

D. Vance, Y. Chen, H. Pan, 2006, Vascular pharmacology.

In vitro phosphorylation of phosphatidylethanolamine N-methyltransferase by cAMP-dependent protein kinase: lack of in vivo phosphorylation in response to N6-2'-O-dibutryladenosine 3',5'-cyclic monophosphate.

D. Vance, N. Ridgway, 1989, Biochimica et biophysica acta.

Fatty acid synthetase activity in Mycobacterium phlei: regulation by polysaccharides.

D. Vance, K. Bloch, E. Mccarthy, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency

P. Neufer, D. Vance, Terence E. Ryan, 2019, Nature Metabolism.

Reciprocal regulation of choline acetyltransferase and choline kinase in sympathetic neurons during cholinergic differentiation.

R. Campenot, D. Vance, D. Ure, 1995, Biochimica et biophysica acta.

Dimethylethanolamine does not prevent liver failure in phosphatidylethanolamine N-methyltransferase-deficient mice fed a choline-deficient diet.

D. Vance, K. Waite, 2004, Biochimica et biophysica acta.

Why Expression of PhosphatidylethanolamineN-Methyltransferase Does Not Rescue Chinese Hamster Ovary Cells That Have an Impaired CDP-Choline Pathway*

D. Vance, K. Waite, 2000, The Journal of Biological Chemistry.

Head group specificity in the regulation of phosphatidylcholine catabolism in rat hepatocytes.

D. Vance, L. Tijburg, 1991, Biochimica et Biophysica Acta.

Head-group specificity for feedback regulation of CTP:phosphocholine cytidylyltransferase.

D. Vance, H. Jamil, 1990, The Biochemical journal.

A stimulating factor for fatty acid biosynthesis--research with Konrad Bloch: mentor and friend.

D. Vance, 2002, Biochemical and biophysical research communications.

Biochemical evidence that Semliki Forest virus obtains its envelope from the plasma membrane of the host cell.

D. Vance, C. Richardson, 1976, The Journal of biological chemistry.

Conversion of phosphatidylethanolamine to phosphatidylcholine.

D. Vance, W. Schneider, 1981, Methods in enzymology.

Tetradecanoyl-phorbol acetate stimulates phosphatidylcholine biosynthesis in HeLa cells by an increase in the rate of the reaction catalyzed by CTP:phosphocholine cytidylyltransferase.

D. Vance, H. Paddon, 1980, Biochimica et biophysica acta.

Trifluoperazine and other anaesthetics inhibit rat liver CTP: phosphocholine cytidylyltransferase

D. Vance, S. Pelech, Fateem Jetha, 1983, FEBS letters.

Effect of diethylstilboestrol on phosphatidylcholine biosynthesis in the liver of roosters.

D. Vance, C. Vigo, 1981, Biochemical Society transactions.

Methyl balance and transmethylation fluxes in humans 1 4 S

M. Brosnan, J. Brosnan, D. Vance, 2006 .

Activities of choline kinase, cholinephosphate cytidylyltransferase and CDP‐choline: 1,2‐diacylglycerol cholinephosphotransferase in brains from normal and quaking mice

D. Vance, W. J. Schneider, 1978, Journal of neurochemistry.

A Role for Sp1 in the Transcriptional Regulation of Hepatic Triacylglycerol Hydrolase in the Mouse*

V. Dolinsky, D. Vance, D. Douglas, 2001, The Journal of Biological Chemistry.

Expression of ABCG1, but Not ABCA1, Correlates with Cholesterol Release by Cerebellar Astroglia*

Barbara Karten, R. Campenot, D. Vance, 2006, Journal of Biological Chemistry.

Analytical Approaches for Investigating Apoptosis and Other Biochemical Events in Compartmented Cultures of Sympathetic Neurons

H. Eng, K. Lund, R. Campenot, 2002 .

Hepatic PEMT activity mediates liver health, weight gain, and insulin resistance

D. Vance, R. Jacobs, R. Nelson, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Phosphatidylethanolamine N-methyltransferase from rat liver.

D. Vance, N. Ridgway, 1992, Methods in Enzymology.

Identification of three novel cDNAs for human phosphatidylethanolamine N-methyltransferase and localization of the human gene on chromosome 17p11.2.

D. Vance, D. Shields, C. Walkey, 1999, Biochimica et biophysica acta.

Characterization of apolipoprotein-mediated HDL generation induced by cAMP in a murine macrophage cell line.

H. Aburatani, D. Vance, S. Yokoyama, 2000, Biochemistry.

Is it time to reevaluate methyl balance in humans?

M. Brosnan, J. Brosnan, D. Vance, 2006, The American journal of clinical nutrition.

Physiological roles of phosphatidylethanolamine N-methyltransferase.

D. Vance, 2013, Biochimica et biophysica acta.

Axonal synthesis of phosphatidylcholine is required for normal axonal growth in rat sympathetic neurons

R. Campenot, D. Vance, J. Vance, 1995, The Journal of cell biology.

In Memoriam: Charles (Chuck) Crawford Sweeley, Jr. (1930–2012)

D. Vance, R. Murphy, A. Merrill, 2013, Journal of Lipid Research.

Protection of Neurons from Apoptosis by Apolipoprotein E-containing Lipoproteins Does Not Require Lipoprotein Uptake and Involves Activation of Phospholipase Cγ1 and Inhibition of Calcineurin*

R. Campenot, D. Vance, H. Hayashi, 2009, The Journal of Biological Chemistry.

Tamoxifen induces triacylglycerol accumulation in the mouse liver by activation of fatty acid synthesis

D. Vance, R. Jacobs, L. Cole, 2010, Hepatology.

Hepatic ratio of phosphatidylcholine to phosphatidylethanolamine predicts survival after partial hepatectomy in mice

D. Vance, T. Chaba, Lin‐Fu Zhu, 2012, Hepatology.

Phosphatidylcholine and choline homeostasis.

D. Vance, Zhaoyu Li, 2008, Journal of lipid research.

Impaired de Novo Choline Synthesis Explains Why Phosphatidylethanolamine N-Methyltransferase-deficient Mice Are Protected from Diet-induced Obesity*

J. Dyck, D. Vance, B. Kennedy, 2010, The Journal of Biological Chemistry.

Conversion of Low Density Lipoprotein-associated Phosphatidylcholine to Triacylglycerol by Primary Hepatocytes*

D. Vance, B. Trigatti, R. Lehner, 2008, Journal of Biological Chemistry.

Inflammation in the Niemann‐Pick type‐C brain

R. Campenot, D. Vance, H. Hayashi, 2007 .

A Role for Hepatic Scavenger Receptor Class B, Type I in Decreasing High Density Lipoprotein Levels in Mice That Lack Phosphatidylethanolamine N-Methyltransferase*

G. Francis, D. Vance, Julie C Robichaud, 2008, Journal of Biological Chemistry.

Choline Deﬁciency–Induced Liver Damage Is Reversible in Pemt / Mice 1

D. Vance, K. Waite, Nora R. Cabilio, 2001 .

The role of phosphatidylethanolamine methyltransferase in a mouse model of intrahepatic cholestasis.

D. Vance, Zhaoyu Li, L. Agellon, 2011, Biochimica et biophysica acta.

Thematic Review Series: Glycerolipids. Phosphatidylcholine and choline homeostasis Published, JLR Papers in Press, January 19, 2008.

D. Vance, Zhaoyu Li, 2008, Journal of Lipid Research.

CTP: phosphocholine cytidylyltransferase from rat liver.

D. Vance, P. Choy, S. Pelech, 1981, Methods in enzymology.

The rate-limiting reaction catalyzed by a multi-enzyme complex-the fatty acid synthetases.

D. Vance, 1976, Journal of theoretical biology.

Localization of the PE methylation pathway and SR-BI to the canalicular membrane Published, JLR Papers in Press, June 16, 2003. DOI 10.1194/jlr.M200488-JLR200

B. Chait, D. Vance, J. Breslow, 2003, Journal of Lipid Research.