P. Wielinga

发表

Characterization of the MRP4- and MRP5-mediated Transport of Cyclic Nucleotides from Intact Cells*

J. Wijnholds, J. Beijnen, P. Wielinga, 2003, The Journal of Biological Chemistry.

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

P. Wielinga, I. van der Heijden, G. Reid, 2003, The Biochemical journal.

Genotyping of Giardia in Dutch patients and animals: a phylogenetic analysis of human and animal isolates.

P. Wielinga, A. de Vries, J. van der Giessen, 2006, International journal for parasitology.

Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs.

P. Wielinga, P. Borst, G. Mulder, 2002, Molecular pharmacology.

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

J. Lankelma, R. Evers, J. Beijnen, 2000, British Journal of Cancer.

In vitro transepithelial drug transport by on-line measurement: cellular control of paracellular and transcellular transport.

H. Westerhoff, J. Lankelma, P. Wielinga, 1999, Journal of Pharmacy and Science.

The relative importance of passive and P-glycoprotein mediated anthracycline efflux from multidrug-resistant cells.

H. Westerhoff, J. Lankelma, P. Wielinga, 2000, European journal of biochemistry.

Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy

P. Wielinga, J. Panetta, J. Schuetz, 2004, Molecular and Cellular Biology.

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.

J. Schellens, P. Wielinga, D. Pluim, 2005, Cancer research.

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

J. Wijnholds, P. Wielinga, P. Borst, 2006, Journal of hepatology.

Ixodes ricinus ticks are reservoir hosts for Rickettsia helvetica and potentially carry flea-borne Rickettsia species

P. Wielinga, C. Reusken, H. Sprong, 2009, Parasites & Vectors.

One Health and Food Safety

P. Wielinga, J. Schlundt, 2014, Confronting Emerging Zoonoses.

Food Safety: At the Center of a One Health Approach for Combating Zoonoses

P. Wielinga, J. Schlundt, 2012, Current topics in microbiology and immunology.

Molecular epidemiology of Cryptosporidium in humans and cattle in The Netherlands.

P. Wielinga, M. Mars, A. de Vries, 2008, International journal for parasitology.

Evidence-based policy for controlling antimicrobial resistance in the food chain in Denmark

F. Aarestrup, P. Wielinga, J. Schlundt, 2014 .

Persistent detection of Babesia EU1 and Babesia microti in Ixodes ricinus in the Netherlands during a 5-year surveillance: 2003-2007.

P. Wielinga, H. Sprong, C. Gaasenbeek, 2009, Vector borne and zoonotic diseases.

Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro

P. Wielinga, W. London, S. Cohn, 2005, Molecular Cancer Therapeutics.

Longitudinal Analysis of Tick Densities and Borrelia, Anaplasma, and Ehrlichia Infections of Ixodes ricinus Ticks in Different Habitat Areas in The Netherlands

L. Schouls, P. Wielinga, W. Dimmers, 2006, Applied and Environmental Microbiology.

Detection of Coxiella burnetii in Complex Matrices by Using Multiplex Quantitative PCR during a Major Q Fever Outbreak in The Netherlands

P. Wielinga, I. Janse, A. de Bruin, 2011, Applied and Environmental Microbiology.

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

J. Wijnholds, R. D. De Abreu, J. Beijnen, 2002, Molecular pharmacology.

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

J. Wijnholds, P. Wielinga, G. Reid, 2004, Antiviral Research.

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

A. Dahan, J. Beijnen, P. Wielinga, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

J. Wijnholds, P. Wielinga, I. van der Heijden, 2003, Proceedings of the National Academy of Sciences of the United States of America.

cGMP transport by vesicles from human and mouse erythrocytes

Piet Borst, Jan Wijnholds, J. Wijnholds, 2007, The FEBS journal.

A method for studying plasma membrane transport with intact cells using computerized fluorometry.

H. Westerhoff, J. Lankelma, P. Wielinga, 1998, Analytical biochemistry.

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes

J. Schulz, J. Wijnholds, P. Wielinga, 2006, Journal of neurochemistry.

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

G. Peters, J. Wijnholds, P. Wielinga, 2005, Cancer research.

Antifolates Folates and Can Mediate Cellular Resistance against The Human Multidrug Resistance Protein MRP 5 Transports

G. Peters, J. Wijnholds, P. Wielinga, 2005 .

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5.

J. Wijnholds, P. Wielinga, G. Reid, 2003, Molecular pharmacology.

Global Microbial Identifier

Ole Lund, Frank Møller Aarestrup, Marion Koopmans, 2017, Applied Genomics of Foodborne Pathogens.

A multiplex real-time PCR for identifying and differentiating B. anthracis virulent types.

P. Wielinga, B. Segerman, R. Knutsson, 2011, International journal of food microbiology.

Lyme borreliosis in the Netherlands: strong increase in GP consultations and hospital admissions in past 10 years.

P. Wielinga, W. van Pelt, A. Hofhuis, 2006, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

P-glycoprotein-independent decrease in drug accumulation by phorbol ester treatment of tumor cells.

J. Lankelma, P. Wielinga, H. Broxterman, 1997, Biochemical pharmacology.

Direct Transfer of Control and Multidrug Resistance

B. Kholodenko, H. Westerhoff, J. Lankelma, 1996 .

Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)*

J. Schellens, P. Wielinga, G. Reid, 2003, Journal of Biological Chemistry.

CHAPTER 21 – THE MULTIDRUG RESISTANCE PROTEINS 3–7

P. Wielinga, G. Reid, P. Borst, 2003 .

Pumping Out Drugs

P. Wielinga, P. Borst, 2006 .

Bioinformatic tools for using whole genome sequencing as a rapid high resolution diagnostic typing tool when tracing bioterror organisms in the food and feed chain.

P. Wielinga, B. Segerman, D. De Medici, 2011, International journal of food microbiology.

Evaluation of DNA extraction methods for Bacillus anthracis spores spiked to food and feed matrices at biosafety level 3 conditions.

P. Wielinga, K. Jordan, G. Bruggeman, 2011, International journal of food microbiology.

Accidental and deliberate microbiological contamination in the feed and food chains--how biotraceability may improve the response to bioterrorism.

Rickard Knutsson, Bart van Rotterdam, Charlotta Löfström, 2011, International journal of food microbiology.

An innovative molecular detection tool for tracking and tracing Clostridium botulinum types A, B, E, F and other botulinum neurotoxin producing Clostridia based on the GeneDisc cycler.

P. Wielinga, B. Segerman, D. De Medici, 2011, International journal of food microbiology.

Online Fluorescent Method to Assess BCRP/ABCG2 Activity in Suspension Cells

R. Pieters, A. Veerman, P. Wielinga, 2004, Nucleosides, nucleotides & nucleic acids.

Towards an international standard for detection and typing botulinum neurotoxin-producing Clostridia types A, B, E and F in food, feed and environmental samples: a European ring trial study to evaluate a real-time PCR assay.

Rickard Knutsson, Elisabetta Delibato, Dario De Medici, 2011, International journal of food microbiology.

[Small risk of developing Lyme borreliosis following a tick bite on Ameland: research in a general practice].

P. Wielinga, A. Brandenburg, G. T. Noordhoek, 2008, Nederlandsch tijdschrift voor geneeskunde.

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

P. Wielinga, N. Zelcer, J. Balzarinib, 2004, Antiviral research.