P. Borst

发表

Characterization of the MRP4- and MRP5-mediated Transport of Cyclic Nucleotides from Intact Cells*

J. Wijnholds, J. Beijnen, P. Wielinga, 2003, The Journal of Biological Chemistry.

Genetic mechanisms of drug resistance. A review.

P. Borst, 1991, Acta oncologica.

Three small RNAs within the 10 kb trypanosome rRNA transcription unit are analogous to domain VII of other eukaryotic 28S rRNAs.

T. C. White, P. Borst, G. Rudenko, 1986, Nucleic acids research.

β-d-glucosyl-hydroxymethyluracil: A novel modified base present in the DNA of the parasitic protozoan T. brucei

P. Borst, J. Kowalak, P. Crain, 1993, Cell.

The gel electrophoresis of DNA.

P. Borst, C. Aaij, P Borst, 1972, Biochimica et biophysica acta.

Mechanism of the Pharmacokinetic Interaction between Methotrexate and Benzimidazoles

J. Schellens, J. Beijnen, P. Borst, 2004, Cancer Research.

Mitochondrial nucleic acids.

L. Grivell, P. Borst, P. Borst, 1973, Annual review of biochemistry.

Base J: discovery, biosynthesis, and possible functions.

P. Borst, R. Sabatini, 2008, Annual review of microbiology.

A new method for fluorescence microscopical localization of specific DNA sequences by in situ hybridization of fluorochromelabelled RNA.

J. Wiegant, P. Borst, P. Duijn, 1980, Experimental cell research.

The pathway of glutamate oxidation by mitochondria isolated from different tissues.

P. Borst, 1962, Biochimica et biophysica acta.

Antigenic Variation in Eukaryotic Parasites

P. Borst, 2002 .

The role of transferrin-receptor variation in the host range of Trypanosoma brucei

P. Borst, W. Bitter, H. Gerrits, 1998, Nature.

Selection for activation of a new variant surface glycoprotein gene expression site in Trypanosoma brucei can result in deletion of the old one.

P. Borst, G. Rudenko, I. Chaves, 1998, Molecular and biochemical parasitology.

Control of VSG gene expression sites in Trypanosoma brucei.

P. Borst, F. van Leeuwen, G. Rudenko, 1998, Molecular and biochemical parasitology.

Two modes of activation of a single surface antigen gene of trypanosoma brucei

P. Borst, Alvin Y. Liu, P. Michels, 1984, Cell.

Two simultaneously active VSG gene transcription units in a single trypanosoma brucei variant

P. Borst, Patricia J. Johnson, J. Kooter, 1985, Cell.

The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei

P. Borst, Patricia J. Johnson, J. Kooter, 1987, Cell.

Structure of a telomeric expression site for variant specific surface antigens in Trypanosoma brucei.

P. Borst, J. Gommers-Ampt, L. V. D. van der Ploeg, 1990, Molecular and biochemical parasitology.

Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.

G. Peters, M. Kool, Y. Assaraf, 1999, Cancer research.

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

P. Wielinga, I. van der Heijden, G. Reid, 2003, The Biochemical journal.

Role of the N-terminal Transmembrane Region of the Multidrug Resistance Protein MRP2 in Routing to the Apical Membrane in MDCKII Cells*

R. Evers, P. Borst, S. B. M. Fernández, 2002, The Journal of Biological Chemistry.

Mammalian ABC transporters in health and disease.

P. Borst, R. Elferink, P Borst, 2002, Annual review of biochemistry.

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

P. Borst, E. de Vries, M. Müller, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome

M. Kool, F. Baas, P. Bosma, 1997, Hepatology.

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

M. Kool, F. Baas, R. Evers, 1998, The Journal of clinical investigation.

MRP3, an organic anion transporter able to transport anti-cancer drugs.

G. Peters, M. Kool, F. Baas, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Control of VSG gene expression sites.

P. Borst, S. Ulbert, 2001, Molecular and biochemical parasitology.

RNA end-labeling and RNA ligase activities can produce a circular rRNA in whole cell extracts from trypanosomes.

T. C. White, P. Borst, 1987, Nucleic acids research.

Genetic dissection of the function of mammalian P-glycoproteins.

P. Borst, A. Schinkel, Piet Borst, 1997, Trends in genetics : TIG.

Search for mitochondrial DNA sequences in chick nuclear DNA.

H. Tabak, P. Borst, A. Tabak, 1973, Biochimica et biophysica acta.

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals.

F. Baas, A. Smith, P. Borst, 1993, Pharmacology & therapeutics.

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.

M. Gottesman, M. Pajic, L. Wessels, 2012, Cancer research.

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

J. Beijnen, P. Borst, A. Sparreboom, 1997, British Journal of Cancer.

Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs.

P. Wielinga, P. Borst, G. Mulder, 2002, Molecular pharmacology.

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

J. Lankelma, R. Evers, J. Beijnen, 2000, British Journal of Cancer.

Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei.

P. Borst, L. V. D. van der Ploeg, A. Bernards, 1982, Nucleic acids research.

Discontinuous synthesis of mRNA in trypanosomes.

P. Borst, T. Lange, T. de Lange, 1984, The EMBO journal.

Trypanosoma brucei: a surface antigen mRNA is discontinuously transcribed from two distinct chromosomes.

P. Borst, E. Pays, A. Cornelissen, 1985, The EMBO journal.

Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum.

A. Smith, P. Borst, A. Schinkel, 1998, Journal of the National Cancer Institute.

The potential use of inhibitors of glycerol‐3‐phosphate oxidase for chemotherapy of African trypanosomiasis

F. Opperdoes, P. Borst, K. Fonck, 1976, FEBS letters.

Particle-bound enzymes in the bloodstream form of Trypanosoma brucei.

F. Opperdoes, P. Borst, H. Spits, 1977, European journal of biochemistry.

Animal peroxisomes (microbodies), lipid biosynthesis and the Zellweger syndrome

P. Borst, 1983 .

Subcellular compartmentation of glycolytic intermediates in Trypanosoma brucei.

F. Opperdoes, P. Borst, N. Visser, 1981, European journal of biochemistry.

Localization of glycerol-3-phosphate oxidase in the mitochondrion and particulate NAD+-linked glycerol-3-phosphate dehydrogenase in the microbodies of the bloodstream form to Trypanosoma brucei.

F. Opperdoes, P. Borst, W. Leene, 1977, European journal of biochemistry.

Oligomycin sensitivity of the mitochondrial ATPase as a marker for fly transmissability and the presence of functional kinetoplast DNA in African trypanosomes.

F. Opperdoes, P. Borst, D. de Rijke, 1976, Comparative biochemistry and physiology. B, Comparative biochemistry.

Trypanosoma brucei: an evaluation of salicylhydroxamic acid as a trypanocidal drug.

F. Opperdoes, C. van der Meer, P. Borst, 1976, Experimental parasitology.

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.

M. Pajic, P. Borst, J. Jonkers, 2010, Cancer research.

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine.

J. Beijnen, P. Borst, A. Sparreboom, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces.

K. Wirtz, T. van der Poll, J. Wijnholds, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice*

R. Evans, D. Moore, G. Reid, 2004, Journal of Biological Chemistry.

How mycoplasma ring the changes

P. Borst, 1992, Current Biology.

Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport

M. Kool, R. Evers, A. Smith, 2000, British Journal of Cancer.

Uncoupling activity of long-chain fatty acids.

E. C. Slater, P. Borst, J. Loos, 1962, Biochimica et biophysica acta.

Availability of PSC833, a Substrate and Inhibitor of P-glycoproteins, in Various Concentrations of Serum

P. Borst, Alexander J. Smith, A. Schinkel, 1998 .

Intestinal BCRP/Bcrp1 and MRP3/Mrp3 are involved in the pharmacokinetics of resveratrol

P. Borst, V. Somoza, A. Bot, 2008 .

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

R. Evers, P. Borst, C. Paulusma, 1999 .

Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage

J. Wijnholds, J. Beijnen, P. Borst, 1998, The Journal of experimental medicine.

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

J. Wijnholds, P. Wielinga, P. Borst, 2006, Journal of hepatology.

Tissue Distribution and Induction of Human Multidrug Resistant Protein 3

M. Kool, P. Borst, M. de Haas, 2002, Laboratory Investigation.

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

F. Baas, J. Lankelma, J. Beijnen, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The modified base J is the target for a nove lDNA‐binding protein in kinetoplastid protozoans

M. Wilm, P. Borst, F. van Leeuwen, 1999, The EMBO journal.

Modification of telomeric DNA in Trypanosoma brucei; a role in antigenic variation?

P. Borst, A. Bernards, N. van Harten-Loosbroek, 1984, Nucleic acids research.

Mice Lacking the Multidrug Resistance Protein 1 Are Resistant to Streptococcus pneumoniae-Induced Pneumonia1

T. van der Poll, J. Wijnholds, P. Speelman, 2001, The Journal of Immunology.

Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini.

J. Boothroyd, G. Cross, P. Borst, 1981, Nucleic acids research.

ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

P. Borst, M. de Haas, M. Haas, 2013, Proceedings of the National Academy of Sciences.

The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase

R. Hausinger, P. Borst, D. Rigden, 2007, Nucleic acids research.

Trypanosoma brucei contains two RNA polymerase II largest subunit genes with an altered C-terminal domain

P. Borst, J. Köck, S. Mémet, 1989, Cell.

Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies.

P. Borst, A. Schinkel, P. Borst, 1991, Cancer research.

Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter.

P. Borst, N. Zelcer, A. Kuil, 2003, The Biochemical journal.

Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP

R. Evers, P. van Bladeren, P. Borst, 1996, FEBS letters.

Tissue distribution of the human MDR3 P-glycoprotein.

A. Jongsma, P. Borst, W. Mooi, 1994, Laboratory investigation; a journal of technical methods and pathology.

Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene

P. Borst, N. Zelcer, R. Elferink, 2005, Hepatology.

Cancer Resistance Protein in Clinical Drug-Drug Interactions Methotrexate and Benzimidazoles : Potential Role for Breast Mechanism of the Pharmacokinetic Interaction between Updated

J. Schellens, J. Beijnen, P. Borst, 2004 .

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

J. H. Beijnen, O. van Tellingen, J. Beijnen, 1994, Cell.

P-glycoprotein ABCB1: a major player in drug handling by mammals.

P. Borst, A. Schinkel, 2013, The Journal of clinical investigation.

From cancer cells to trypanosomes and back again

P. Borst, Ph.D. For Mem RS. Staff member and Director Emeritus of M. D., 2006, Cellular and Molecular Life Sciences CMLS.

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier Wijnholds,

J. Wijnholds, P. Borst, M. Valk, 2000 .

New physiological functions for drug-transporting P-glycoproteins?

P. Borst, W. V. van Blitterswijk, J. Borst, 1998, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Hepatocyte‐specific expression of the human MDR3P‐glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (−/−) mice

P. Borst, Alexander J. Smith, A. Schinkel, 1998, Hepatology.

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

P. Borst, A. Schinkel, Piet Borst, 1996, European journal of cancer.

Amplification of Several Different Genes in Multidrug-Resistant Chinese Hamster Cell Lines

P. Borst, A. Bliek, 1991 .

Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line

A. M. van der Bliek, P. Borst, V. Ling, 1986, Molecular and cellular biology.

What Makes Tumors Multidrug Resistant?

P. Borst, J. Jonkers, S. Rottenberg, 2007, Cell cycle.

Characterization of Drug Transport by the Human Multidrug Resistance Protein 3 (ABCC3)*

J. Beijnen, G. Reid, P. Borst, 2001, The Journal of Biological Chemistry.

The tissue dependent expression of hamster P‐glycoprotein genes

F. Baas, P. Borst, 1988, FEBS letters.

Hydrogen transport and transport metabolites

P. Borst, 1963 .

MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping*

G. Szakács, A. Smith, E. Welker, 2000, The Journal of Biological Chemistry.

A 22‐kd protein (sorcin/V19) encoded by an amplified gene in multidrug‐resistant cells, is homologous to the calcium‐binding light chain of calpain.

A. M. van der Bliek, P. Borst, J. L. Biedler, 1986, The EMBO journal.

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.

R. Evers, P. Borst, C. Paulusma, 1999, The Biochemical journal.

Size-fractionation of the small chromosomes of Trypanozoon and Nannomonas trypanosomes by pulsed field gradient gel electrophoresis.

P. Borst, W. Gibson, Wendy Gibson, 1986, Molecular and biochemical parasitology.

Mapping of VSG genes on large expression-site chromosomes of Trypanosoma brucei separated by pulsed-field gradient electrophoresis.

P. Borst, P. J. Johnson, 1986, Gene.

Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules

D. Schwartz, C. Cantor, P. Borst, 1984, Cell.

Chromosome rearrangements in trypanosoma brucei

P. Borst, P. Michels, A. Cornelissen, 1984, Cell.

HELB Is a Feedback Inhibitor of DNA End Resection.

Grant W. Brown, A. Gingras, D. Durocher, 2016, Molecular cell.

HELB Is a Feedback Inhibi tor of DNA End Resection Graphical Abstract Highlights

Grant W. Brown, A. Gingras, D. Durocher, 2016 .

Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P‐glycoprotein

F. Baas, R. Arceci, T. Tsuruo, 1993, International journal of cancer.

Structure and transcription of a telomeric surface antigen gene of Trypanosoma brucei

P. Borst, A. Bernards, J. Kooter, 1985, Molecular and cellular biology.

CHAPTER 22 – LIPID TRANSPORT BY ABC TRANSPORTERS

P. Borst, G. Meer, R. P. Elferink, 2003 .

Reduced topoisomerase II activity in multidrug-resistant human non-small cell lung cancer cell lines.

F. Baas, P. Borst, M. de Haas, 1995, British Journal of Cancer.

How do real tumors become resistant to cisplatin?

P. Borst, J. Jonkers, S. Rottenberg, 2008, Cell cycle.

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

P. Borst, A. Schinkel, E. Wagenaar, 1995, The Journal of clinical investigation.

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.

J. Beijnen, P. Borst, A. Schinkel, 1997, The Journal of clinical investigation.

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins.

P. Borst, H. Spits, O. van Tellingen, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.

D D Breimer, J. Wijnholds, P. Borst, 2000, The Journal of clinical investigation.

Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol

Piet Borst, Veronika Somoza, P. Borst, 2009, Molecular Pharmacology.

Do cMOAT (MRP2), other MRP homologues, and LRP play a role in MDR?

M. Kool, R. Evers, P. Borst, 1997, Seminars in cancer biology.

MRP2 and 3 in health and disease.

P. Borst, N. Zelcer, K. van de Wetering, 2006, Cancer letters.

Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines

A. M. van der Bliek, P. Borst, M. D. de Bruijn, 1986, Molecular and cellular biology.

The H circles of Leishmania tarentolae are a unique amplifiable system of oligomeric DNAs associated with drug resistance.

T. C. White, P. Borst, J. Calafat, 1988, The Journal of biological chemistry.

Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania

P. Borst, C. Dumas, B. Papadopoulou, 2005, Nucleic acids research.

The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei. Presence of repeated elements at its border and absence of promoter-associated sequences.

P. Borst, L. V. D. van der Ploeg, L. Ploeg, 1983, Journal of molecular biology.

A freeze-squeeze method for recovering long DNA from agarose gels.

P. Borst, J. Sanders, R. Thuring, 1975, Analytical biochemistry.

The synthesis and utilization of dCDP-diglyceride by a mitochondrial fraction from rat liver.

P. Borst, K. Hostetler, H. van den Bosch, 1971, Biochimica et biophysica acta.

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice.

J. Beijnen, P. Borst, O. van Tellingen, 1996, Journal of the National Cancer Institute.

Mechanisms of Antigenic Variation: An Overview

P. Borst, 2003 .

Fine structure of the 21S ribosomal RNA region on yeast mitochondrial DNA

C. Heyting, P. Borst, P. Weijers, 1979, Molecular and General Genetics MGG.

Fine structure of the 21S ribosomal RNA region on yeast mitochondrial DNA

C. Heyting, P. Borst, J. Bos, 1979, Molecular and General Genetics MGG.

Fine structure physical mapping of 4S RNA genes on mitochondrial DNA ofSaccharomyces cerevisiae

P. Borst, G. Ommen, G. Groot, 1977, Molecular and General Genetics MGG.

The organization of gene in yeast mitochondrial DNA

C. Heyting, P. Borst, M. Verbeet, 2004, Molecular and General Genetics MGG.

Why kinetoplast DNA networks?

P. Borst, Piet Borst, 1991, Trends in genetics : TIG.

Insertion of the promoter for a variant surface glycoprotein gene expression site in an RNA polymerase II transcription unit of procyclic Trypanosoma brucei.

P. Borst, R. Kieft, J. Zomerdijk, 1993, Molecular and biochemical parasitology.

Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences

P. Borst, G. Rudenko, R. McCulloch, 1997, Molecular and cellular biology.

Controlled turnover and 3' trimming of the trans splicing precursor of Trypanosoma brucei.

P. Laird, P. Borst, A. T. ten Asbroek, 1987, Nucleic acids research.

Multidrug resistance mediated by P-glycoproteins.

P. Borst, A. Schinkel, 1991, Seminars in cancer biology.

Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3′ end

J. Boothroyd, G. Cross, P. Borst, 1981, Cell.

THE USE OF RECOMBINANT DNA TECHNIQUES IN THE ANALYSIS OF TRYPANOSOMA BRUCEI KINETOPLAST DNA

P. Borst, J. Davison, F. Brunel, 1980 .

Platelet-activating factor: mediator of the third pathway of platelet aggregation? A study in three patients with deficient platelet-activating factor synthesis.

J. T. ten Cate, P. Borst, R. Schutgens, 1987, The Journal of clinical investigation.

Resistant Lung Cancer Cell Lines Transmembrane Drug Transporter , in Human Multidrug , the Gene for a New Putative MRP Analysis of the Expression of Updated Version

F. Baas, P. Borst, N. Mulder, 2006 .

Advances in Brief Antifolate Resistance Mediated by the Multidrug Resistance Proteins MRP 1 and MRP 21

G. Peters, M. Kool, Y. Assaraf, 2000 .

Analysis of a variant surface glycoprotein gene expression site promoter of Trypanosoma brucei by remodelling the promoter region.

P. Borst, P. Blundell, 1998, Molecular and biochemical parasitology.

Frequent Loss of the Active Site during Variant Surface Glycoprotein Expression Site Switching In Vitro inTrypanosoma brucei

P. Borst, M. Taylor, M. Cross, 1998, Molecular and Cellular Biology.

Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei.

G. A. van der Marel, P. Borst, F. van Leeuwen, 1997, Genes & development.

Targeting of exogenous DNA into Trypanosoma brucei requires a high degree of homology between donor and target DNA.

P. Borst, G. Rudenko, P. Blundell, 1996, Molecular and biochemical parasitology.

Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of Trypanosoma brucei

M. Ouellette, P. Borst, A. Asbroek, 1990, Nature.

Nucleoside analysis of DNA from Trypanosoma brucei and Trypanosoma equiperdum.

P. Borst, P. J. Johnson, Patricia J. Johnson, 1988, Molecular and biochemical parasitology.

Coincident multiple activations of the same surface antigen gene in Trypanosoma brucei.

P. Borst, T. de Lange, J. Kooter, 1987, Journal of molecular biology.

Kinetoplast DNA of Trypanosoma evansi.

P. Borst, W. Gibson, F. Fase-Fowler, 1987, Molecular and biochemical parasitology.

Rapid change of the repertoire of variant surface glycoprotein genes in trypanosomes by gene duplication and deletion.

P. Borst, J. Calafat, W. Gibson, 1986, Journal of molecular biology.

Trypanosome variant surface glycoprotein genes expressed early in infection.

P. Borst, P. Michels, A. Bernards, 1985, Journal of molecular biology.

Telomere conversion in trypanosomes.

P. Borst, P. Michels, T. de Lange, 1983, Nucleic acids research.

The control of variant surface antigen synthesis in trypanosomes.

P. Borst, P. Michels, L. V. D. van der Ploeg, 1983, European journal of biochemistry.

Size fractionation of Trypanosoma brucei DNA: localization of the 177-bp repeat satellite DNA and a variant surface glycoprotein gene in a mini-chromosomal DNA fraction.

P. Borst, P. Sloof, M. Caspers, 1983, Nucleic acids research.

Growth of chromosome ends in multiplying trypanosomes

P. Borst, P. Michels, A. Bernards, 1983, Nature.

Activation of the genes for variant surface glycoproteins 117 and 118 in Trypanosoma brucei.

P. Borst, P. Michels, G. Veeneman, 1983, Journal of molecular biology.

Genomic environment of the expression-linked extra copies of genes for surface antigens of Trypanosoma brucei resembles the end of a chromosome

P. Borst, T. Lange, 1982, Nature.

Molecular basis for trypanosome antigenic variation

G. Cross, P. Borst, 1982, Cell.

Characterization of the expression-linked gene copies of variant surface glycoprotein 118 in two independently isolated clones of Trypanosoma brucei.

P. Borst, P. Michels, L. V. D. van der Ploeg, 1982, Nucleic acids research.

DNA rearrangements involving the genes for variant antigens in Trypanosoma brucei.

A. Frasch, A. Arnberg, G. Cross, 1981, Cold Spring Harbor symposia on quantitative biology.

Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei

A. Fairlamb, P. Borst, J. Hoeijmakers, 1978, The Journal of cell biology.

ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

P. Borst, A. Bergen, A. Váradi, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

P. Borst, Kenneth A. Johnson, A. Fish, 2012, Journal of the American Chemical Society.

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1

M. J. Chalmers, P. Griffin, P. Borst, 2011, Nucleic acids research.

Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J.

P. Borst, S. Vainio, B. ter Riet, 2009, Molecular and biochemical parasitology.

vidence that J-binding protein 2 is a thymidine hydroxylase catalyzing he first step in the biosynthesis of DNA base

P. Borst, B. T. Riet, P. Genest, 2009 .

Biosynthesis, and Possible Functions

P. Borst, R. Sabatini, 2008 .

DNAA modification and base excision repair in Trypanosoma brucei

E. Seeberg, P. Borst, S. Ulbert, 2007 .

A minor fraction of base J in kinetoplastid nuclear DNA is bound by the J-binding protein 1.

P. Borst, R. Sabatini, R. Kieft, 2005, Molecular and biochemical parasitology.

Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis.

P. Borst, R. Boorstein, S. Ulbert, 2002, Nucleic acids research.

Site-specific Interactions of JBP with Base and Sugar Moieties in Duplex J-DNA

P. Borst, J. V. van Boom, R. Sabatini, 2002, The Journal of Biological Chemistry.

Recognition of Base J in Duplex DNA by J-binding Protein*

P. Borst, J. V. van Boom, R. Sabatini, 2002, The Journal of Biological Chemistry.

Tandemly repeated DNA is a target for the partial replacement of thymine by beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.

P. Borst, F. van Leeuwen, F. Leeuwen, 2000, Molecular and biochemical parasitology.

Biosynthesis and Function of the Modified DNA Base β-d-Glucosyl-Hydroxymethyluracil inTrypanosoma brucei

P. Borst, F. van Leeuwen, R. Kieft, 1998, Molecular and Cellular Biology.

The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.

G. A. van der Marel, P. Borst, F. van Leeuwen, 1998, Analytical biochemistry.

beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.

P. Borst, F. van Leeuwen, H. Moreau, 1998, Proceedings of the National Academy of Sciences of the United States of America.

beta-D-glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida.

P. Borst, F. van Leeuwen, 1997, Molecular and biochemical parasitology.

A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei

P. Borst, G. Rudenko, R. Kieft, 1995, Cell.

A ribosomal RNA gene promoter at the telomere of a mini-chromosome in Trypanosoma brucei.

P. Borst, R. Kieft, J. Zomerdijk, 1992, Nucleic acids research.

Topogenesis of microbody enzymes: a sequence comparison of the genes for the glycosomal (microbody) and cytosolic phosphoglycerate kinases of Trypanosoma brucei.

F. Opperdoes, P. Borst, P. Michels, 1985, The EMBO journal.

Chromosomes of kinetoplastida.

P. Borst, J. Barry, L. V. D. van der Ploeg, 1984, The EMBO journal.

Post-transcriptional control of the differential expression of phosphoglycerate kinase genes in Trypanosoma brucei.

P. Borst, W. Gibson, B. Swinkels, 1988, Journal of molecular biology.

Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line.

A. Jongsma, A. M. van der Bliek, P. Borst, 1987, Cancer research.

Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. II. Sequence evolution of the minicircles.

P. Borst, J. Hoeijmakers, 1982, Plasmid.

Maxi-circles and mini-circles in kinetoplast DNA from trypanosoma cruzi.

A. Frasch, P. Borst, J. Hoeijmakers, 1980, Biochimica et biophysica acta.

The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei.

G. Cross, P. Borst, J. Hoeijmakers, 1980, Gene.

RNA from the insect trypanosome Crithidia luciliae contains transcripts of the maxi-circle and not of the mini-circle component of kinetoplast DNA.

P. Borst, J. Hoeijmakers, 1978, Biochimica et biophysica acta.

Changing the end: antigenic variation orchestrated at the telomeres of African trypanosomes.

P. Borst, G. Rudenko, M. Cross, 1998, Trends in microbiology.

Delineation of the regulated Variant Surface Glycoprotein gene expression site domain of Trypanosoma brucei.

P. Borst, G. Rudenko, Karen Sheader, 2003, Molecular and biochemical parasitology.

Analysis of telomere length variation in Leishmania over time.

P. Borst, P. Genest, 2007, Molecular and biochemical parasitology.

Trypanosomes change their transferrin receptor expression to allow effective uptake of host transferrin

P. Borst, M. Engstler, B. ter Riet, 2005, Molecular microbiology.

Factors Affecting the Level and Localization of the Transferrin Receptor in Trypanosoma brucei*

P. Borst, J. Onderwater, H. Koerten, 2004, Journal of Biological Chemistry.

Expression site activation in Trypanosoma brucei with three marked variant surface glycoprotein gene expression sites.

P. Borst, I. Chaves, S. Ulbert, 2002, Molecular and biochemical parasitology.

Control of variant surface glycoprotein gene‐expression sites in Trypanosoma brucei

P. Borst, G. Rudenko, I. Chaves, 1999, The EMBO journal.

Mono-allelic expression of genes in simple eukaryotes.

P. Borst, I. Chaves, 1999, Trends in genetics : TIG.

The expression sites for variant surface glycoproteins of Trypanosoma brucei.

G. H. Coombs, J. Mottram, P. Borst, 1997 .

VSG gene expression site control in insect form Trypanosoma brucei.

P. Borst, G. Rudenko, R. Kieft, 1994, The EMBO journal.

Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features.

P. Borst, P. Shiels, R. Kieft, 1991, Nucleic acids research.

REPLICATION OF VIRAL RNA. IV. PROPERTIES OF RNA SYNTHETASE AND ENZYMATIC SYNTHESIS OF MS2 PHAGE RNA.

M. Billeter, S. Ochoa, P. Borst, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Molecular genetics of antigenic variation

P. Borst, 1991 .

Induced Pneumonia pneumoniae-Streptococcus Protein 1 Are Resistant to Mice Lacking the Multidrug Resistance

J. Wijnholds, P. Speelman, P. Borst, 2001 .

DNA circles with cruciforms from Isospora (Toxoplasma) gondii.

P. Borst, M. van den Berg, J. P. Overdulve, 1984, Biochimica et biophysica acta.

The structure of Tetrahymena pyriformis mitochondrial DNA. I. Strain differences and occurrence of inverted repetitions.

A. Arnberg, P. Borst, J. Défize, 1977, Biochimica et biophysica acta.

The structure of kinetoplast DNA. I. Properties of the intact multi-circular complex from Crithidia luciliae.

P. Borst, P. Weijers, C. M. Kleisen, 1975, Biochimica et biophysica acta.

The unusual properties of mtDNA from a "low-density" petite mutant of yeast.

C. Hollenberg, A. Arnberg, P. Borst, 1972, Biochimica et biophysica acta.

Mechanisms of multidrug-resistance

F. Baas, P. Borst, A. Schinkel, 1994 .

Does resistance to apoptosis affect clinical response to antitumor drugs?

P. Borst, J. Borst, L. Smets, 2001, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

The presence of DNA molecules with a displacement loop in standard mitochondrial DNA preparations.

A. Arnberg, P. Borst, E. van Bruggen, 1971, Biochimica et biophysica acta.

Preface/Front Matter

P. Slonimski, Giuseppe Attardi, P. Borst, 1982 .

Replication of the linear mitochondrial DNA of Tetrahymena pyriformis.

P. Borst, R. Goldbach, E. van Bruggen, 1979, Biochimica et biophysica acta.

The intracellular localization of glutamate-oxaloacetate transaminases in heart.

P. Borst, E. Peeters, 1961, Biochimica et biophysica acta.

An analysis by electron microscopy of intermediates in the replication of linear Tetrahymena mitochondrial DNA.

A. Arnberg, P. Borst, R. Clegg, 1974, Biochimica et biophysica acta.

The structure of kinetoplast DNA. 2. Characterization of a novel component of high complexity present in the kinetoplast DNA network of Crithidia luciliae.

P. Borst, K. Fonck, P. O. Weislogel, 1976, European journal of biochemistry.

Parasitology: Switching like for like

P. Borst, P. Genest, 2006, Nature.

Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei

P. Borst, R. Kieft, J. Zomerdijk, 1991, Nature.

Unicellular eukaryotes are not devoid of ADPRT

P. Borst, 1987 .

Does the absence of ABCC6 (Multidrug Resistance Protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?

P. Borst, R. Schlingemann, K. van de Wetering, 2008, Cell cycle.

Control of Antigenic Variation in African Trypanosomas

P. Borst, F. van Leeuwen, M. Ligtenberg, 1993 .

The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.

P. Borst, F. van Leeuwen, W. Gibson, 1998, Molecular and biochemical parasitology.

The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei.

P. Borst, M. Ligtenberg, G. Rudenko, 1996, Nucleic acids research.

Transferrin receptor, antigenic variation and the prospect of a trypanosome vaccine.

P. Borst, 1991, Trends in genetics : TIG.

The inactivation and reactivation of an expression‐linked gene copy for a variant surface glycoprotein in Trypanosoma brucei.

P. Borst, Alvin Y. Liu, P. Michels, 1984, The EMBO journal.

Mitochondrial DNA: V. A 25-μ closed circular duplex DNA molecule in wild-type yeast mitochondria. Structure and genetic complexity

C. Hollenberg, P. Borst, E. V. Bruggen, 1970 .

The aerobic oxidation of reduced diphosphopyridine nucleotide formed by glycolysis in Ehrlich ascites-tumour cells.

P. Borst, 1962, Biochimica et biophysica acta.

DNA-DNA hybridization on nitrocellulose filters. 1. General considerations and non-ideal kinetics.

P. Borst, R. Flavell, J. Sanders, 1974, European journal of biochemistry.

Biochemical methods to locate genes on the physical map of yeast mitochondrial DNA.

C. Heyting, P. Borst, J. Sanders, 1979, Methods in enzymology.

Introduction: multidrug resistant proteins

P. Borst, 1997 .

Molecular parasitology at woods hole

V. Nussenzweig, P. Borst, 1992, Cell.

MRP 3 , an organic anion transporter able to transport anti-cancer drugs ( multidrug resistance y methotrexate y etoposide )

Ronald, Scheper, Smith, 1999 .

Cancer chemotherapy: DNA amplification and multidrug resistance

P. Borst, 1984, Nature.

Renaturation of mitochondrial DNA.

P. Borst, G. Ruttenberg, 1966, Biochimica et biophysica acta.

DNA‐DNA Hybridization on Nitrocellulose Filters

P. Borst, R. Flavell, J. Sanders, 1974 .

cDNA cloning and tissue-specific expression of the phosphatidylcholine transfer protein gene.

K. Wirtz, A. Smith, P. Borst, 1996, The Biochemical journal.

Mega-dose vitamin C as therapy for human cancer?

P. Borst, 2008, Proceedings of the National Academy of Sciences.

Molecular Basis for Trypanosome Antigenic Variation Review

P. Borst, Kent Br, 1982 .

Gel electrophoresis of RNA under denaturing conditions.

L. Reijnders, P. Borst, P. Sloof, 1973, Biochimica et biophysica acta.

Transcription of Tetrahymena mitochondrial DNA in vivo.

L. Reijnders, P. Borst, S. Hoekstra, 1973, Biochimica et biophysica acta.

The effect of temperature and ionic strength of the electrophoretic mobility of yeast mitochondrial RNA.

L. Grivell, L. Reijnders, P. Borst, 1971, European journal of biochemistry.

Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania

P. Myler, B. Steensel, P. Borst, 2012, Cell.

Mitochondrial DNA: physicochemical properties, replication, and genetic function.

P. Borst, A. Kroon, 1969, International review of cytology.

On the DNA content and ploidy of trypanosomes.

M. van der Ploeg, P. Borst, J. Tas, 1982, Molecular and biochemical parasitology.

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

M. Kool, F. Baas, P. Borst, 1997, Cancer research.

Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin.

S. Moestrup, P. Borst, E. Nexo, 2010, Blood.

A family of drug transporters: the multidrug resistance-associated proteins.

M. Kool, R. Evers, J. Wijnholds, 2000, Journal of the National Cancer Institute.

MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

Piet Borst, Ingo Fritzsche, P. Borst, 1996, Cell.

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids

P. Borst, A. Fish, M. Altelaar, 2015, Proceedings of the National Academy of Sciences.

New mechanisms of drug resistance in parasitic protozoa.

M. Ouellette, P. Borst, Piet Borst, 1995, Annual review of microbiology.

Kinetoplast DNA

P. Borst, J. Hoeijmakers, 1993, Current Biology.

The site of action of 2,4-dinitrophenol on oxidative phosphorylation

E. C. Slater, P. Borst, 1961 .

New approach to screening drugs for activity against African trypanosomes

F. Opperdoes, A. Fairlamb, P. Borst, 1977, Nature.

Metabolism and chemotherapy of African trypanosomes.

P. Borst, 1977, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Properties of mitochondrial DNA from Kluyveromyces lactis.

P. Borst, G. Groot, P. Weijers, 1974, Biochimica et biophysica acta.

Preparation and Properties of Mitochondria from Ehrlich Ascites Tumor Cells

P. Borst, 1960, The Journal of biophysical and biochemical cytology.

Severe plasmalogen deficiency in tissues of infants without peroxisomes (Zellweger syndrome)

P. Borst, H. Heymans, H. Bosch, 1983, Nature.

Novel expression-linked copies of the genes for variant surface antigens in trypanosomes

A. Frasch, G. Cross, P. Borst, 1980, Nature.

Structure and function of mitochondrial DNA

P. Borst, 1977 .

The mitochondrial genome of yeast

L. Grivell, P. Borst, 1978, Cell.

DNA synthesis by isolated mitochondria. I. Effect of inhibitors and characterization of the product.

P. Borst, J. ter Schegget, 1971, Biochimica et biophysica acta.

Surface receptors and transporters of Trypanosoma brucei.

A. Fairlamb, P. Borst, 1998, Annual review of microbiology.

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1

R. Evers, J. Wijnholds, P. van Bladeren, 1997, FEBS letters.

Localization of nine glycolytic enzymes in a microbody‐like organelle in Trypanosoma brucei: The glycosome

F. Opperdoes, P. Borst, F R Opperdoes, 1977, FEBS letters.

Mitochondrial nucleic acids.

L. Grivell, P. Borst, 1974, Biochimie.

Splice point sequence and transcripts of the intervening sequence in the mitochondrial 21S ribosomal RNA gene of yeast

H. Tabak, P. Borst, G. Ommen, 1980, Cell.

Isolation of yeast mitochondrial ribosomes highly active in protein synthesis.

L. Grivell, L. Reijnders, P. Borst, 1971, Biochimica et biophysica acta.

The organization of genes in yeast mitochondrial DNA

P. Borst, P. Weijers, J. Sanders, 1975, Molecular and General Genetics MGG.

Hybridization studies with yeast mitochondrial RNAs.

L. Grivell, L. Reijnders, P. Borst, 1972, Biochimica et biophysica acta.

Hybridization studies with RNA synthesized by isolated rat-liver mitochondria.

C. Saccone, P. Borst, C. Aaij, 1970, Biochimica et biophysica acta.

Mitochondrial antibiotic resistance in yeast: ribosomal mutants resistant to chloramphenicol, erythromycin and spiramycin.

L. Grivell, P. Slonimski, P. Borst, 1973, Biochimica et biophysica acta.

Mitochondrial DNA. I. Preparation and properties of mitochondrial DNA from chick liver.

P. Borst, J. Ruttenberg, A. Kroon, 1967, Biochimica et biophysica acta.

The number of 4-S RNA genes on yeast mitochondrial DNA.

L. Reijnders, P. Borst, 1972, Biochemical and biophysical research communications.

Telomere exchange can be an important mechanism of variant surface glycoprotein gene switching in Trypanosoma brucei.

P. Borst, G. Rudenko, R. McCulloch, 1996, Molecular and biochemical parasitology.

The common 5' terminal sequence on trypanosome mRNAs: a target for anti-messenger oligodeoxynucleotides.

J. Toulmé, P. Borst, B. Swinkels, 1986, Nucleic acids research.

Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

P. Borst, A. Berns, A. Groen, 1993, Cell.

Maxi-circles, glycosomes, gene transposition, expression sites, transsplicing, transferrin receptors and base J.

P. Borst, 2016, Molecular and biochemical parasitology.

A phosphoglycerate kinase-related gene conserved between Trypanosoma brucei and Crithidia fasciculata.

F. Opperdoes, P. Borst, B. Swinkels, 1992, Molecular and biochemical parasitology.

Trypanosoma brucei variant-specific glycoprotein gene chromatin is sensitive to single-strand-specific endonuclease digestion.

D. Greaves, P. Borst, 1987, Journal of molecular biology.

Discontinuous transcription and antigenic variation in trypanosomes.

P. Borst, P Borst, 1986, Annual review of biochemistry.

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei.

P. Laird, P. Borst, J. Zomerdijk, 1987, The EMBO journal.

Antigenic variation in malaria

P. Borst, G. Rudenko, F. Leeuwen, 1995, Cell.

Deficiency of plasmalogens in the cerebro-hepato-renal (Zellweger) syndrome

P. Borst, H. Heymans, J. Müller‐Höcker, 1984, European Journal of Pediatrics.

How proteins get into microbodies (peroxisomes, glyoxysomes, glycosomes).

P. Borst, Piet Borst, 1986, Biochimica et biophysica acta.

REPLICATION OF VIRAL RNA.

M. Billeter, S. Ochoa, P. Borst, 1964, Federation proceedings.

Antigenic Variation and Allelic Exclusion

P. Borst, 2002, Cell.

Direct and inverted DNA repeats associated with P‐glycoprotein gene amplification in drug resistant Leishmania.

M. Ouellette, P. Borst, E. Hettema, 1991, EMBO Journal.

Many trypanosome messenger RNAs share a common 5' terminal sequence.

P. Borst, P. Michels, T. Lange, 1984, Nucleic acids research.

The multidrug resistance protein family.

M. Kool, R. Evers, J. Wijnholds, 1999, Biochimica et biophysica acta.

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

J. Wijnholds, R. D. De Abreu, J. Beijnen, 2002, Molecular pharmacology.

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

J. Wijnholds, P. Wielinga, G. Reid, 2004, Antiviral Research.

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs.

F. Baas, E. De Clercq, J. Wijnholds, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

R. Evers, P. Borst, H. Jansen, 1996, The Journal of clinical investigation.

Multidrug resistance-associated proteins 3, 4, and 5

P. Borst, C. Wolf, K. Wetering, 2007, Pflügers Archiv - European Journal of Physiology.

Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides

Piet Borst, Jan Wijnholds, J. Wijnholds, 2008, Molecular Cancer Therapeutics.

ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs*

P. Borst, M. de Haas, K. van de Wetering, 2015, The Journal of Biological Chemistry.

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

P. Borst, A. Lau, M. O’Connor, 2008, Proceedings of the National Academy of Sciences.

Do predictive signatures really predict response to cancer chemotherapy?

L. Wessels, P. Borst, 2010, Cell cycle.

Small is beautiful — portrait of a mitochondrial genome

L. Grivell, P. Borst, 1981, Nature.

Response of BRCA 1-Deficient Mammary Tumors Impact of Intertumoral Heterogeneity on Predicting Chemotherapy

M. Gottesman, L. Wessels, S. Linn, 2012 .

Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells.

M. Kool, F. Baas, P. Borst, 1999, Cancer research.

Expression of HumanMRP6, a Homologue of the Multidrug Resistance Protein GeneMRP1, in Tissues and Cancer Cells

M. Kool, F. Baas, P. Borst, 1998 .

Expression of Human MRP 6 , a Homologue of the Multidrug Resistance Protein Gene MRP 1 , in Tissues and Cancer Cells 1

M. Kool, F. Baas, P. Borst, 1998 .

Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA.

A. M. van der Bliek, P. Borst, G. Schuurhuis, 1990, Cancer research.

Mechanisms of MRP over‐expression in four human lung‐cancer cell lines and analysis of the MRP amplicon

F. Baas, P. Borst, M. Breuning, 1995, International journal of cancer.

Structure of amplified DNA, analyzed by pulsed field gradient gel electrophoresis

A. M. van der Bliek, P. Borst, T. van der Velde-Koerts, 1987, Journal of cellular biochemistry.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Peter Bouwman, Jiri Bartek, Kees Jalink, 2015, Nature.

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

Shridar Ganesan, Jos Jonkers, Piet Borst, 2013, Cancer discovery.

BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.

L. Wessels, A. Schlicker, P. Borst, 2015, Cancer research.

The physiological significance of transferrin receptor variations in Trypanosoma brucei.

P. Borst, W. Bitter, H. Gerrits, 2002, Molecular and biochemical parasitology.

Erroneous transcription of mitochondrial DNA by RNA polymerase from Escherichia coli.

H. Tabak, P. Borst, 1970, Biochimica et biophysica acta.

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

P. Bosma, P. Borst, C. Paulusma, 1996, Science.

Characterization of the promoter region of the human MDR3 P-glycoprotein gene.

P. Borst, A. Schinkel, E. Wagenaar, 1995, Biochimica et biophysica acta.

Sequence of mdr3 cDNA encoding a human P-glycoprotein.

A. M. van der Bliek, P. Borst, C. Schneider, 1988, Gene.

The human mdr3 gene encodes a novel P‐glycoprotein homologue and gives rise to alternatively spliced mRNAs in liver.

F. Baas, A. M. van der Bliek, P. Borst, 1987, The EMBO journal.

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

Jos Jonkers, Piet Borst, Marina Pajic, 2007, Proceedings of the National Academy of Sciences.

Expressionn site activation in Trypanosoma brucei with threee marked variant surface glycoprotein gene expressionn sites

P. Borst, I. Chaves, S. Ulbert, 2007 .

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt‐based anti‐cancer drugs

L. Wessels, T. Brummelkamp, P. Borst, 2015, The EMBO journal.

Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo

M. Pajic, P. Borst, J. Jonkers, 2010, Cell cycle.

Drug resistance in the mouse cancer clinic.

P. Borst, S. Rottenberg, 2012, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Structure of the growing telomeres of trypanosomes

P. Borst, Alvin Y. Liu, L. Ploeg, 1984, Cell.

Recognition by P-Glycoprotein-specific Monoclonal Antibodies 3 P-Glycoprotein and Its MDR Characterization of the Human Updated Version

P. Borst, A. Schinkel, M. Roelofs, 2006 .

Altered MRP is associated with multidrug resistance and reduced drug accumulation in human SW-1573 cells.

F. Baas, P. Borst, M. Flens, 1995, British Journal of Cancer.

The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway

P. Borst, 2020, IUBMB life.

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

A. Dahan, J. Beijnen, P. Wielinga, 2005, Proceedings of the National Academy of Sciences of the United States of America.

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

J. Wijnholds, P. Wielinga, I. van der Heijden, 2003, Proceedings of the National Academy of Sciences of the United States of America.

cGMP transport by vesicles from human and mouse erythrocytes

Piet Borst, Jan Wijnholds, J. Wijnholds, 2007, The FEBS journal.

Cancer cell death by programmed necrosis?

P. Borst, S. Rottenberg, 2004, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance

Hans Clevers, Jos Jonkers, Piet Borst, 2017, Nature Methods.

REPLICATION OF VIRAL RNA, III. DOUBLE-STRANDED REPLICATIVE FORM OF MSW PHAGE RNA.

M. Billeter, S. Ochoa, P. Borst, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

M. Lopes, L. Wessels, J. Bartek, 2018, Cancer cell.

A study of minor RNA components of rat-liver microsomes.

P. Borst, C. Aaij, C. A. Agsteribbe, 1971, Biochimica et biophysica acta.

Genes amplified and overexpressed in human multidrug-resistant cell lines.

F. Baas, R. Ozols, A. M. van der Bliek, 1988, Cancer research.

Mechanisms of antigenic variation in African trypanosomes.

P. Borst, F. van Leeuwen, G. Rudenko, 1997, Behring Institute Mitteilungen.

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei.

M. Ouellette, C. Clayton, P. Borst, 1990, The EMBO journal.

Programmed gene rearrangements altering gene expression.

D. Greaves, P. Borst, 1987, Science.

Specific detection of kinetoplast DNA in cytological preparations of trypanosomes by hybridization with complementary RNA.

P. Borst, M. Steinert, S. Van Assel, 1973, Experimental cell research.

Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer.

M. Pajic, P. Borst, J. Jonkers, 2009, Cancer research.

Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions.

R. Evers, P. Borst, B. Sarkadi, 2000, Molecular pharmacology.

Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain*

G. Szakács, R. Evers, G. Tusnády, 1998, The Journal of Biological Chemistry.

The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models

Jos H. Beijnen, Piet Borst, Gerrit Jansen, 2007, Molecular Pharmacology.

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

G. Peters, J. Wijnholds, P. Wielinga, 2005, Cancer research.

Antifolates Folates and Can Mediate Cellular Resistance against The Human Multidrug Resistance Protein MRP 5 Transports

G. Peters, J. Wijnholds, P. Wielinga, 2005 .

The glutamate dehydrogenases of yeast: extra-mitochondrial enzymes.

C. Hollenberg, P. Borst, W. F. Riks, 1970, Biochimica et biophysica acta.

Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?

P. Borst, Piet Borst, 2012, Open Biology.

ABC transporters in lipid transport.

P. Borst, N. Zelcer, A. van Helvoort, 2000, Biochimica et biophysica acta.

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5.

J. Wijnholds, P. Wielinga, G. Reid, 2003, Molecular pharmacology.

Peroxisome biogenesis revisited.

P. Borst, 1989, Biochimica et biophysica acta.

EZN-2208 (PEG-SN38) Overcomes ABCG2-Mediated Topotecan Resistance in BRCA1-Deficient Mouse Mammary Tumors

P. Borst, J. Jonkers, S. Rottenberg, 2012, PloS one.

Need for Inorganic Phosphate in Oxidations stimulated by Dinitrophenol

P. Borst, E. Slater, 1959, Nature.

Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy.

A. Smith, P. Borst, J. Crawford, 1997, The Journal of clinical investigation.

An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome.

F. Grosveld, P. Borst, T. Lange, 1982, Nucleic acids research.

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

Jos H. Beijnen, Piet Borst, Jan Wijnholds, 1997, Nature Medicine.

The human MDR3 P‐glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice

K. Wirtz, B. Roelofsen, P. Borst, 1994, FEBS letters.

Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies.

M. Kool, J. Wijnholds, P. Borst, 2000, Cancer research.

Peripheral Neuropathy in Mice Transgenic for a HumanMDR3 P-Glycoprotein Mini-Gene

F. Baas, G. Jansen, P. Borst, 1996, The Journal of Neuroscience.

Human multidrug resistance 3-P-glycoprotein expression in transgenic mice induces lens membrane alterations leading to cataract

P. Borst, M. A. van der Valk, I. Dunia, 1996, The Journal of cell biology.

Structure and Function of P-Glycoproteins

P. Borst, A. Schinkel, J. Smit, 1992 .

Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing

Tyson A. Clark, J. Korlach, Matthew Boitano, 2015, Nucleic acids research.

The structure of Tetrahymena pyriformis mitochondrial DNA. II. The complex structure of strain GL mitochondrial DNA.

A. Arnberg, P. Borst, R. Goldbach, 1977, Biochimica et biophysica acta.

Characterization of satellite DNA in Trypanosoma brucei and Trypanosoma cruzi.

P. Borst, J. Bos, P. Sloof, 1983, Journal of molecular biology.

The amplified H circle of methotrexate‐resistant leishmania tarentolae contains a novel P‐glycoprotein gene.

M. Ouellette, P. Borst, F. Fase-Fowler, 1990, The EMBO journal.

CHAPTER 4 XRN 2 loss causes PARP inhibitor and cisplatin resistance of BRCA 1-deficient mouse mammary tumor cells

P. Borst, J. Jonkers, P. Bouwman, 2015 .

Looking back at multidrug resistance (MDR) research and ten mistakes to be avoided when writing about ABC transporters in MDR

P. Borst, 2020, FEBS letters.

Substantial excretion of digoxin via the intestinal mucosa and prevention of long‐term digoxin accumulation in the brain by the mdrla P‐glycoprotein

Piet Borst, J. Beijnen, P. Borst, 1996, British journal of pharmacology.

Multidrug resistance and the role of P-glycoprotein knockout mice.

P. Borst, A. Schinkel, E. Wagenaar, 1995, European journal of cancer.

Inactivation of transcription by UV irradiation of T. brucei provides evidence for a multicistronic transcription unit including a VSG gene

P. Borst, Patricia J. Johnson, J. Kooter, 1987, Cell.

Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm.

T. Ishikawa, I. van der Heijden, P. Borst, 2007, The Biochemical journal.

STRUCTURE OF PETITE mtDNA; PROSPECTS FOR MITOCHONDRIAL GENE ISOLATION, MAPPING AND SEQUENCING

P. Borst, 1974 .

Pyrimidine tract analysis of mtDNA from a "low-density" petite mutant of yeast.

C. Hollenberg, P. Borst, R. Flavell, 1972, Biochimica et biophysica acta.

DNA synthesis by isolated mitochondria. 3. Characterization of D-loop DNA, a novel intermediate in mtDNA synthesis.

P. Borst, R. Flavell, J. ter Schegget, 1971, Biochimica et biophysica acta.

Mitochondrial DNA from cytoplasmic petite mutants of yeast.

C. Hollenberg, P. Borst, E. van Bruggen, 1972, Biochimica et biophysica acta.

Mitochondrial DNA. 3. Electron microscopy of DNA released from mitochondria by osmotic shock.

P. Borst, A. Kroon, E. van Bruggen, 1968, Biochimica et biophysica acta.

The organization of repeating units in mitochondrial DNA from yeast petite mutants

C. Heyting, P. Borst, J. Bos, 1980, Current Genetics.

Conditions that prevent ϱ−-induction by ethidium bromide

C. Hollenberg, P. Borst, 1971 .

Size, structure and genetic complexity of yeast mitochondrial DNA.

C. Hollenberg, P. Borst, E. van Bruggen, 1969, Biochimica et biophysica acta.

DNA synthesis by isolated mitochondria. IV. Isolation of an intermediate containing newly synthesized DNA in full-length light strands.

P. Borst, R. Flavell, J. ter Schegget, 1972, Biochimica et biophysica acta.

The structure of kinetoplast DNA. 1. The mini-circles of Crithidia lucilae are heterogeneous in base sequence.

P. Borst, P. Weijers, C. M. Kleisen, 1976, European journal of biochemistry.

Mitochondrial DNA. IV. Interaction of ribopolynucleotides with the complementary strands of chick-liver mitochondrial DNA.

P. Borst, G. Ruttenberg, 1969, Biochimica et biophysica acta.

The number of superhelical turns in mitochondrial DNA.

P. Borst, E. Smit, E. van Bruggen, 1968, Biochimica et biophysica acta.

Mitochondrial DNA. II. Sedimentation analysis and electron microscopy of mitochondrial DNA from chick liver.

P. Borst, A. Kroon, E. van Bruggen, 1967, Biochimica et biophysica acta.

The molecular weights of the mitochondrial-ribosomal RNAs of Saccharomyces carlsbergensis.

L. Reijnders, P. Borst, P. Sloof, 1973, European journal of biochemistry.

The organization of genes in yeast mitochondrial DNA

P. Borst, J. Sanders, 2004, Molecular and General Genetics MGG.

Conservation of the sequence and position of the ribosomal RNA genes in Tetrahymena pyriformis mitochondrial DNA.

P. Borst, R. Goldbach, E. van Bruggen, 1978, Biochimica et biophysica acta.

The organization of ribosomal RNA genes in the mitochondrial DNA of Tetrahymena pyriformis strain ST.

P. Borst, R. Goldbach, E. van Bruggen, 1978, Biochimica et biophysica acta.

DNA-DNA hybridization on nitrocellulose filters. 2. Concatenation effects.

P. Borst, R. Flavell, E. J. Birfelder, 1974, European journal of biochemistry.

Intermediates in the replication of the mitochondrial DNA of Tetrahymena pyriformis.

P. Borst, R. Clegg, P. Weijers, 1974, Biochimica et biophysica acta.

DNA synthesis by isolated mitochondria. V. Electron microscopy of replicative intermediates.

A. Arnberg, P. Borst, R. Flavell, 1973, Biochimica et biophysica acta.

DNA synthesis by isolated mitochondria. II. Detection of product DNA hydrogen-bonded to closed duplex circles.

P. Borst, J. ter Schegget, 1971, Biochimica et biophysica acta.

Identification of the heavy strand of rat-liver mitochondrial DNA as the messenger strand.

P. Borst, C. Aaij, 1969, Biochemical and biophysical research communications.

Two tandemly linked identical genes code for the glycosomal glyceraldehyde‐phosphate dehydrogenase in Trypanosoma brucei.

F. Opperdoes, P. Borst, J. V. Van Beeumen, 1986, The EMBO journal.

Comparison of the genes coding for the common 5' terminal sequence of messenger RNAs in three trypanosome species.

A. Frasch, P. Borst, J. Barry, 1984, Nucleic acids research.

Replication of viral RNA, 8. Studies on the enzymatic mechanism of replication of MS2 RNA.

P. Borst, C. Weissmann, 1965, Proceedings of the National Academy of Sciences of the United States of America.

[Multiple D-loops in Tetrahymena mitochondrial DNA].

A. Arnberg, P. Borst, R. Flavell, 1972, Biochimica et biophysica acta.

An analysis of a possible base sequence complementarity of mitochondrial and nuclear DNA in yeast.

C. Hollenberg, P. Borst, L. Cohen, 1970, Biochimica et biophysica acta.

The Physical Map of Yeast Mitochondrial DNA Anno 1977 (A Review)

L. Grivell, A. Moorman, C. Heyting, 1977 .

Mitochondrial DNA. V. A 25 micron closed circular duplex DNA molecule in wild-type yeast mitochondria. Stucture and genetic complexity.

C. Hollenberg, P. Borst, E. van Bruggen, 1970, Biochimica et biophysica acta.

Kinetoplast DNA from Trypanosoma vivax and T. congolense.

L. Tetley, P. Borst, J. Barry, 1985, Molecular and biochemical parasitology.

Analysis by electron microscopy of the variable segment in the maxi-circle of kinetoplast DNA from Trypanosoma brucei.

P. Borst, G. Brakenhoff, P. Weijers, 1982, Biochimica et biophysica acta.

Antigenic variation in trypanosomes.

P. Borst, F. van Leeuwen, G. Rudenko, 1983 .

Tandem repetition of the 5′ mini-exon of variant surface glycoprotein genes: A multiple promoter for VSG gene transcription?

P. Borst, Alvin Y. Liu, T. Lange, 1983, Cell.

Rapid evolution of genes coding for variant surface glycoproteins in trypanosomes.

A. Frasch, P. Borst, J. van den Burg, 1982, Gene.

An insert in the single gene for the large ribosomal RNA in yeast mitochondrial DNA

C. Heyting, A. Arnberg, P. Borst, 1978, Nature.

Genes on Saccharomyces Mitochondrial DNA

P. Slonimski, C. Heyting, P. Borst, 1976 .

Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. I. Sequence evolution and transcription of the maxicircle.

P. Borst, J. Hoeijmakers, B. Schoutsen, 1982, Plasmid.

Molecular genetics of antigenic variation.

P. Borst, P Borst, 1991, Immunology today.

Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. III. Heteroduplex analysis of the C. luciliae minicircles.

P. Borst, J. Hoeijmakers, G. Brakenhoff, 1982, Plasmid.

Transcription of kinetoplast DNA in Trypanosoma brucei bloodstream and culture forms.

P. Borst, J. Hoeijmakers, J. Janssen, 1981, Plasmid.

Variations in maxi-circle and mini-circle sequences in kinetoplast DNAs from different Trypanosoma brucei strains.

A. Frasch, P. Borst, J. Hoeijmakers, 1980, Biochimica et biophysica acta.

STRUCTURE AND FUNCTION OF KINETOPLAST DNA OF THE AFRICAN TRYPANOSOMES

P. Borst, J. Hoeijmakers, 1979 .

Maxi-circles in the kinetoplast DNA of Trypanosoma mega.

P. Borst, M. Steinert, S. Van Assel, 1977, Experimental cell research.

Characterization of kinetoplast DNA networks from the insect trypanosome Crithidia luciliae.

A. Fairlamb, P. Borst, J. Hoeijmakers, 1977, Biochimica et biophysica acta.

Sequence heterogeneity of the mini-circles of kinetoplast DNA of Crithidia luciliae and evidence for the presence of a component more complex than mini-circle DNA in the kinetoplast network.

P. Borst, C. M. Kleisen, Piet Borst, 1975, Biochimica et biophysica acta.

Circular mitochondrial DNA.

P. Borst, A. Kroon, M. Gruber, 1966, Biochimica et biophysica acta.

The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands

Jacques H. van Boom, Piet Borst, Fred van Leeuwen, 1996, Nucleic Acids Res..

Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)*

J. Schellens, P. Wielinga, G. Reid, 2003, Journal of Biological Chemistry.

CHAPTER 21 – THE MULTIDRUG RESISTANCE PROTEINS 3–7

P. Wielinga, G. Reid, P. Borst, 2003 .

On the putative co‐transport of drugs by multidrug resistance proteins

P. Borst, B. Poolman, N. Zelcer, 2006, FEBS letters.

Mini-review MRP 2 and 3 in health and disease

P. Borst, N. Zelcer, K. Wetering, 2006 .

Multidrug resistance: a solvable problem?

P. Borst, 1999, Annals of oncology : official journal of the European Society for Medical Oncology.

Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays

J. Brouwers, P. Borst, M. Haas, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Multidrug Resistance Proteins 2 and 3 Provide Alternative Routes for Hepatic Excretion of Morphine-Glucuronides

J. Beijnen, P. Borst, N. Zelcer, 2007, Molecular Pharmacology.

Selected Alkylating Agents Can Overcome Drug Tolerance of G0-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice

M. Pajic, P. Borst, J. Jonkers, 2017, Clinical Cancer Research.

Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo.

J. Brouwers, J. Helms, P. Borst, 2009, Gastroenterology.

PXE, a Mysterious Inborn Error Clarified.

P. Borst, A. Váradi, K. van de Wetering, 2019, Trends in biochemical sciences.

ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum.

J. Uitto, P. Borst, T. Arányi, 2011, Biochemical and biophysical research communications.

The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.

R. Evers, P. Borst, E. Martinoia, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Pumping Out Drugs

P. Wielinga, P. Borst, 2006 .

Multidrug resistant proteins.

P. Borst, 1997, Seminars in cancer biology.

Mitochondrial ribosomes

L. Grivell, P. Borst, 1971, FEBS Letters.

Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei.

P. Borst, I. Chaves, R. Dirks, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Stable transformation of Trypanosoma brucei.

P. Borst, A. T. Ten Asbroek, C. Mol, 1993, Molecular and biochemical parasitology.

Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes.

P. Borst, P Borst, J. Kooter, 1984, Nucleic acids research.

Investigation of the alpha-galactosidase deficiency in Fabry's disease using antibodies against the purified enzyme.

P. Borst, J. Tager, J. Molenaar, 1974, European journal of biochemistry.

Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania.

M. Ouellette, P. Borst, Piet Borst, 1991, Research in microbiology.

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes.

P. Borst, P. Michels, G. Veeneman, 1982, Nucleic acids research.

Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype.

F. Baas, A. Jongsma, P. Borst, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of DNA from Trypanosoma brucei and related trypanosomes by restriction endonuclease digestion

A. Frasch, P. Borst, J. Hoeijmakers, 1980 .

One gene's intron is another gene's exon

L. Grivell, P. Borst, 1981, Nature.

A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic ‘tail’ absent from purified glycoprotein

J. Boothroyd, G. Cross, P. Borst, 1980, Nature.

The kinetoplast DNA of Trypanosoma equiperdum.

A. Frasch, S. Hajduk, P. Borst, 1980, Biochimica et biophysica acta.

The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei.

N. Hall, M. Berriman, S. Bowman, 2002, Molecular and biochemical parasitology.

Characterization of the gene for the microbody (glycosomal) triosephosphate isomerase of Trypanosoma brucei.

P. Borst, J. H. Boom, G. Veeneman, 1986, The EMBO journal.

Evidence for gene conversion between the phosphoglycerate kinase genes of Trypanosoma brucei.

P. Borst, W. Gibson, S. L. Le Blancq, 1988, Journal of molecular biology.

Further analysis of intraspecific variation in Trypanosoma brucei using restriction site polymorphisms in the maxi-circle of kinetoplast DNA.

P. Borst, W. Gibson, F. Fase-Fowler, 1985, Molecular and biochemical parasitology.

The binding of polyribonucleotides to the complementary strands of mitochondrial DNA.

P. Borst, G. Ruttenberg, 1972, Biochimica et biophysica acta.

Reactions involved in energy transfer in trypanosomes-I. Characterization of the mitochondrial adenine nucleotide translocator and the ATPase of Crithidia luciliae.

F. Opperdoes, P. Borst, D. D. Rijke, 1976, Comparative biochemistry and physiology. B, Comparative biochemistry.

The major transcripts of the kinetoplast DNA of Trypanosoma brucei are very small ribosomal RNAs

Jan H. J. Hoeijmakers, I. C. Eperon, J. W. Janssen, 1983, Nucleic Acids Res..

Circular DNA of 3T6R50 double minute chromosomes.

A. M. van der Bliek, P. Borst, C. Lincke, 1988, Nucleic acids research.

DNA content and structure of (double) minutes of a methotrexate-resistant cell line

A. Jongsma, P. Borst, W. Duijndam, 2004, Histochemistry.

Doxorubicin sensitivity and acquired resistance of Pgp-and BRCA 1-deficient mouse mammary tumors

P. Borst, S. Rottenberg, A. Kersbergen, 2012 .

Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?

P. Borst, 2012, Open Biology.

The Evolutionary Origin of Glycosomes: How Glycolysis Moved from Cytosol to Organelle in Evolution

P. Borst, B. Swinkels, 1989 .

Trypanosomes of subgenus Trypanozoon are diploid for housekeeping genes.

P. Borst, P. Michels, W. Gibson, 1985, Molecular and biochemical parasitology.

REV 7 counteracts DNA double-strand break resection and impacts PARP inhibition

Kees, J. Bartek, J. Bártková, 2015 .

UvA-DARE ( Digital Academic Repository ) Base J originally found in kinetoplastida is also a minor constituent of nuclear DNA of Euglena

P. Borst, W. Martin, I. Chaves, 2000 .

Reconstitution of a surface transferrin binding complex in insect form Trypanosoma brucei.

P. Borst, J. Calafat, H. Janssen, 1994, The EMBO journal.

Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania

P. Borst, T. Cijsouw, B. ter Riet, 2007, Nucleic acids research.

Secondary loss of chloroplasts in trypanosomes

P. Borst, W. Martin, 2003, Proceedings of the National Academy of Sciences of the United States of America.

J‐binding protein increases the level and retention of the unusual base J in trypanosome DNA

Piet Borst, P. Borst, I. Chaves, 2002, Molecular microbiology.

Further characterization of the extremely small mitochondrial ribosomal RNAs from trypanosomes: a detailed comparison of the 9S and 12S RNAs from Crithidia fasciculata and Trypanosoma brucei with rRNAs from other organisms.

R. Gutell, H. Noller, P. Borst, 1985, Nucleic acids research.

Alpha-amanitin-resistant transcription units in trypanosomes: a comparison of promoter sequences for a VSG gene expression site and for the ribosomal RNA genes.

P. Borst, P Borst, P. Shiels, 1991, Nucleic acids research.

Changes in expression site control and DNA modification in Trypanosoma brucei during differentiation of the bloodstream form to the procyclic form.

P. Borst, F. van Leeuwen, R. Brun, 1998, Molecular and biochemical parasitology.

Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases.

E. Seeberg, P. Borst, S. Ulbert, 2004, DNA repair.

The physiological role of mdr2 P-glycoprotein in hepatobiliary phospholipid transport

P. Borst, A. Groen, A. Schinkel, 1997 .

Some yeast mitochondrial RNAs are circular

L. Grivell, A. Arnberg, P. Borst, 1980, Cell.

Common elements on the surface of glycolytic enzymes from Trypanosoma brucei may serve as topogenic signals for import into glycosomes.

F. Opperdoes, J. Postma, P. Borst, 1987, The EMBO journal.

Boundaries of telomere conversion in Trypanosoma brucei.

P. Borst, A. Winter, J. Kooter, 1988, Gene.

Effect of 3-aminobenzamide on antigenic variation of Trypanosoma brucei.

C. van der Meer, P. Borst, F. Farzaneh, 1985, Biochemical pharmacology.

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei

C. Clayton, P. Borst, J. Calafat, 2002, Molecular microbiology.

Pulsed field gradient electrophoresis of DNA digested in agarose allows the sizing of the large duplication unit of a surface antigen gene in trypanosomes.

P. Borst, P. Michels, A. Bernards, 1986, Gene.

Transcription of a transposed trypanosome surface antigen gene starts upstream of the transposed segment.

P. Borst, J. Luirink, T. de Lange, 1985, The EMBO journal.

ADP-ribosyl transferase activity in Trypanosoma brucei.

P. Borst, F. Farzaneh, P. Michels, 1985, Molecular and biochemical parasitology.

Quantitation of genetic differences between Trypanosoma brucei gambiense, rhodesiense and brucei by restriction enzyme analysis of kinetoplast DNA.

P. Borst, W. Gibson, F. Fase-Fowler, 1981, Molecular and biochemical parasitology.

The genes for the variable surface glycoproteins of Trypanosoma brucei.

A. Frasch, G. Cross, P. Borst, 1980 .

The genes for variant antigens in trypanosomes.

A. Frasch, G. Cross, P. Borst, 1980, The American journal of tropical medicine and hygiene.

Formation of self-complementary RNA on a single strand of DNA by RNA polymerase from Escherichia coli.

H. Tabak, P. Borst, 1971, Biochimica et biophysica acta.

Variation with temperature of the apparent molecular weight of rat-liver mitochondrial RNA, determined by gel electrophoresis.

P. Borst, C. Aaij, P. Groot, 1970, Biochemical and biophysical research communications.

ACCUMULATION OF REPLICATIVE INTERMEDIATES OF MITOCHONDRIAL DNA IN TETRAHYMENA PYRIFORMIS GROWN IN ETHIDIUM BROMIDE

P. Borst, W. B. Upholt, 1974, Journal of Cell Biology.

The structure of ribosome-like particles from rat-liver mitochondria.

P. Borst, C. Aaij, N. Nanninga, 1972, Biochimica et biophysica acta.

Mitochondrial RNA from rat liver.

P. Borst, C. Aaij, 1970, Biochimica et biophysica acta.

Ethidium DNA agarose gel electrophoresis: How it started

P. Borst, 2005, IUBMB life.

Renaturation of denatured DNA in NaI gradients

P. Borst, R. Clegg, 1974, Molecular Biology Reports.

Optimal conditions for primer-dependent transcription of poly (dT) by RNA polymerase.

P. Borst, C. F. V. Kreijl, 1973 .

The topogenic signal of the glycosomal (microbody) phosphoglycerate kinase of Crithidia fasciculata resides in a carboxy‐terminal extension.

R. Evers, P. Borst, B. Swinkels, 1988, The EMBO journal.

Detection and properties of an acid -galactosidase (ceramidetrihexosidase) in normal human urine.

P. Borst, J. Tager, P. Rietra, 1972, Biochimica et biophysica acta.

The oxidation of glutamate by rat-heart sarcosomes.

P. Borst, E. Slater, 1960, Biochimica et biophysica acta.

THE DPN CONTENT OF MITOCHONDRIA ISOLATED FROM ASCITES- TUMOUR CELLS TREATED WITH A CARCINOSTATIC ETHYLENEIMINE.

P. Borst, H. Holzer, H. Grimberg, 1963, Biochimica et biophysica acta.

The pyridine nucleotide content of mitochondria isolated from Ehrlich ascites tumour cells.

P. Borst, J. COLPA-BOONSTRA, 1962, Biochimica et biophysica acta.

Edward Charles Slater. 16 January 1917 — 26 March 2016

P. Borst, 2017, Biographical Memoirs of Fellows of the Royal Society.

Mature mRNAs of Trypanosoma brucei possess a 5' cap acquired by discontinuous RNA synthesis.

P. Laird, P. Borst, J. Kooter, 1985, Nucleic acids research.

A fused chimeric protein made in human cells

H. Tabak, P. Borst, R. Benne, 1989, Cell.

Lack of ABCG2 Shortens Latency of BRCA1-Deficient Mammary Tumors and This Is Not Affected by Genistein or Resveratrol

P. Borst, J. Jonkers, S. Rottenberg, 2012, Cancer Prevention Research.

Lack of ABCG 2 shortens latency of BRCA 1-deficient mammary tumors and this is not 1 affected by genistein or resveratrol 2 3

P. Borst, J. Jonkers, S. Rottenberg, 2012 .

Phosphatidylcholline transfer protein (PC-TP)

P. Borst, 2002 .

Characteristics of trypanosome variant antigen genes active in the tsetse fly

Piet Borst, A. W. Cornelissen, G. A. Bakkeren, 1985, Nucleic Acids Res..

Mitochondrial mosaics — maturases on the move

L. Grivell, P. Borst, 1982, Nature.

Are 50% of all cellular proteins synthesized on mitochondrial ribosomes in Crithidia luciliae?

P. Borst, C. M. Kleisen, 1975, Biochimica et biophysica acta.

Transcription of mitochondrial DNA.

L. Grivell, H. Tabak, P. Borst, 1983, CRC critical reviews in biochemistry.

The kinetoplast DNA of Trypanosoma brucei: structure, evolution, transcription, mutants.

A. Frasch, P. Borst, J. Hoeijmakers, 1980 .

The maxi-circle of Trypanosoma brucei kinetoplast DNA.

P. Borst, F. Fase-Fowler, Piet Borst, 1979, Biochimica et biophysica acta.

Stable introduction of exogenous DNA into Trypanosoma brucei.

P. Laird, P. Borst, T. White, 1987, The EMBO journal.

Further characterization oftheextremely small mitochondrial ribosomal RNAsfrom trypanosomes: adetailed comparison ofthe9Sand12SRNAsfromCrithidia fasciculata and Trypanosoma brucei withrRNAsfromother organisms

P. Borst, A. Voogd, M. Agostinelli, 1985 .

Reinvestigation into the Synthesis of Oligonucleotides Containing 5‐(β‐D‐Glucopyranosyloxymethyl)‐2′‐deoxyuridine

P. Borst, J. H. Boom, G. A. Marel, 2003 .

The Biogenesis of Mitochondria in Yeast and Other Primitive Eukaryotes

P. Borst, 1981 .

The Optional Introns in Yeast Mitochondrial DNA

P. Borst, 1980 .

Intramitochondrial localization of 5-aminolaevulinate synthase induced in rat liver with allylisopropylacetamide.

P. Borst, F. Huijing, F. Zuyderhoudt, 1969, Biochimica et biophysica acta.

The Synthesis of Yeast Mitochondrial Proteins in Cell-free Systems

P. Borst, D. Y. Thomas, M. J. Eggitt, 1976 .

Nucleic Acids Research

P. Borst, J. Kooter, Paul A. M. Michds, 2013, Nucleic Acids Research.

2. Introduction

P. Borst, 2022 .

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

F. Baas, J. Lankelma, P. Borst, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?

P. Borst, 2012 .

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

M. Lopes, L. Wessels, J. Bartek, 2019, Cancer cell.

Mechanisms of MRP over‐expression in four human lung‐cancer cell lines and analysis of the MRP amplicon

F. Baas, P. Borst, M. Breuning, 1995, International journal of cancer.

Multidrug resistance in human lung cancer

F. Baas, P. Borst, M. Haas, 1993 .

Antigenic variation in African trypanosomes.

P. Borst, G. Rudenko, 1994, Science.

How I became a biochemist

P. Borst, 2006, IUBMB life.

THE REPLICATIVE FORM OF MS2 RNA: AN X-RAY DIFFRACTION STUDY.

R. Langridge, M. Billeter, P. Borst, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Hypermodified bases in DNA

P. Borst, J. Gommers-Ampt, J. H.Gommers‐Ampt, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

2. Introduction

P. Borst, Piet Borst, Piet Borst, 2017, Types of Christian Theology.

Drug resistance in the mouse cancer clinic.

P. Borst, S. Rottenberg, 2012, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs*

P. Borst, M. de Haas, K. van de Wetering, 2015, The Journal of Biological Chemistry.

Altered MRP is associated with multidrug resistance and reduced drug accumulation in human SW-1573 cells.

F. Baas, P. Borst, E. Kamst, 1995, British Journal of Cancer.

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

M. Lopes, L. Wessels, J. Bartek, 2018, Cancer cell.

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

S. Ganesan, J. Doroshow, P. Borst, 2013, Cancer discovery.

Control of variant surface glycoprotein gene‐expression sites in Trypanosoma brucei

P. Borst, G. Rudenko, I. Chaves, 1999, The EMBO journal.