G. Fleet

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POTENT INHIBITION OF GLYCOGEN PHOSPHORYLASE BY A SPIROHYDANTOIN OF GLUCOPYRANOSE : FIRST PYRANOSE ANALOGUES OF HYDANTOCIDIN

L. Johnson, C. Bichard, E. Mitchell, 1995 .

Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure

L. Johnson, K. Watson, S. Zographos, 1999, Protein science : a publication of the Protein Society.

The antibody binding site. Labelling of a specific antibody against the photo-precursor of an aryl nitrene.

G. Fleet, R. Porter, J. Knowles, 1972, The Biochemical journal.

Affinity Labelling of Antibodies with Aryl Nitrene as Reactive Group

J. Knowles, G. Fleet, R. Porter, 1969, Nature.

Towards time-resolved diffraction studies with glycogen phosphorylase.

G. P. Reid, J. Hajdu, L. Johnson, 1991, Ciba Foundation symposium.

Synthesis and Biological Characterisation of Novel N‐Alkyl‐Deoxynojirimycin α‐Glucosidase Inhibitors

R. Dwek, G. Fleet, D. Alonzi, 2009, Chembiochem : a European journal of chemical biology.

The isolation by ligand affinity chromatography of a novel form of alpha-L-fucosidase from almond.

R. Dwek, T. Rademacher, G. Fleet, 1990, The Journal of biological chemistry.

Purification to homogeneity of Charonia lampas alpha-fucosidase by using sequential ligand-affinity chromatography.

G. Fleet, T. Butters, P. Scudder, 1991, The Biochemical journal.

The design of potential antidiabetic drugs: experimental investigation of a number of β-D-glucose analogue inhibitors of glycogen phosphorylase

L. Johnson, C. Bichard, E. Mitchell, 1994, European Journal of Drug Metabolism and Pharmacokinetics.

Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure

L. Johnson, K. Watson, S. Zographos, 1999, Protein science : a publication of the Protein Society.

Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells

R. Dwek, G. Fleet, D. C. Neville, 2010, Glycoconjugate Journal.

Looking glass inhibitors: efficient synthesis and biological evaluation of D-deoxyfuconojirimycin.

R. Dwek, G. Fleet, T. Butters, 2005, Carbohydrate research.

α-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptides

L. Johnson, N. Oikonomakos, G. Fleet, 1996 .

Spirohydantoins of glucofuranose: Analogues of hydantocidin

P. D. Lilley, L. Johnson, N. Oikonomakos, 1995 .

1,4-Dideoxy-1,4-imino-D-mannitol inhibits glycoprotein processing and mannosidase.

G. Fleet, M. Mitchell, A. Elbein, 1985, Archives of biochemistry and biophysics.

Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a d-glucotriazole carboxylate

L. Pickering, S. Zographos, N. Oikonomakos, 1997 .

Enantiomeric 2-acetamido-1,4-dideoxy-1,4-iminoribitols as potential pyrrolidine hexosaminidase inhibitors

R. Dwek, G. Fleet, T. Butters, 2011 .

Aminosugar derivatives as potential anti-human immunodeficiency virus agents.

G S Jacob, R. Dwek, N. Ramsden, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of cell wall-associated enzymes in vitro and in vivo with sugar analogs.

G. Fleet, S. Tu, S. Namgoong, 1990, Plant physiology.

Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.

L. Johnson, C. Bichard, E. Mitchell, 1995, Acta crystallographica. Section D, Biological crystallography.

2-Hydroxymethyl-3,4-dihydroxy-6-methyl-pyrrolidine (6-deoxy-DMDP), an alkaloid beta-mannosidase inhibitor from seeds of Angylocalyx pynaertii.

G. Fleet, A. Elbein, J. Tropea, 1993, Journal of natural products.

Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.

L. Johnson, N. Ramsden, N. Oikonomakos, 1991, Biochemistry.

Inhibition of β-N-Acetylglucosaminidase by Glycon-Related Analogues of the Substrate

M. Horsch, G. Fleet, D. Rast, 1993 .

Inhibition of human ovarian carcinoma cell- and hexosaminidase- mediated degradation of extracellular matrix by sugar analogs.

G. Fleet, H. Wikiel, R. Bernacki, 1992, Anticancer research.

Inhibition of alpha-L-fucosidase by derivatives of deoxyfuconojirimycin and deoxymannojirimycin.

G. Fleet, B. Winchester, G. Jacob, 1990, The Biochemical journal.

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.

L. Johnson, C. Bichard, E. Mitchell, 1994, Biochemistry.

The structural basis of the inhibition of human alpha-mannosidases by azafuranose analogues of mannose.

G. Fleet, B. Winchester, S. Choi, 1993, The Biochemical journal.

Anomeric specificity of D-xylose isomerase.

D. Blow, G. Fleet, C. Collyer, 1992, Biochemistry.

Preparation, biochemical characterization and biological properties of radiolabelled N-alkylated deoxynojirimycins.

L. Pickering, R. Dwek, M. Wormald, 2002, The Biochemical journal.

Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase

Georgios Archontis, Evangelia D Chrysina, K. Watson, 2005, Proteins.

N‐acetyl‐β‐D‐glucopyranosylamine: A potent T‐state inhibitor of glycogen phosphorylase. A comparison with α‐D‐glucose

L. Johnson, C. Bichard, K. Watson, 1995, Protein science : a publication of the Protein Society.

The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 Å resolution and 100 K: The role of the water structure and its contribution to binding

L. Johnson, K. Watson, N. Oikonomakos, 1998, Protein science : a publication of the Protein Society.

Amino-sugar glycosidase inhibitors: versatile tools for glycobiologists.

G. Fleet, B. Winchester, G. Fleet, 1992, Glycobiology.

Effects of C-1-substituted glucose analogue on the activation states of glycogen synthase and glycogen phosphorylase in rat hepatocytes.

L. Johnson, M. Bollen, G. Fleet, 1995, The Biochemical journal.