A. Mankin

发表

Programmed drug‐dependent ribosome stalling

H. Ramu, A. Mankin, N. Vázquez-Laslop, 2009, Molecular microbiology.

Structure and function of ribosomal RNA.

C. Merryman, H. Noller, S. Joseph, 1995, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Assembly and functionality of the ribosome with tethered subunits

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2019, Nature Communications.

Inactivation of the Indigenous Methyltransferase RlmN in Staphylococcus aureus Increases Linezolid Resistance

A. Mankin, B. Howden, J. LaMarre, 2011, Antimicrobial Agents and Chemotherapy.

Synthesis and biological investigation of new 4''-malonyl tethered derivatives of erythromycin and clarithromycin.

A. Mankin, A. Melman, D. Sherman, 2006, Bioorganic & medicinal chemistry letters.

A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre

A. Mankin, P. Mauvais, L. Xiong, 1999, Molecular microbiology.

Surface topography of ribosomal RNA.

A. Mankin, A. Bogdanov, A. Kopylov, 1988, Methods in enzymology.

Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2020, bioRxiv.

Retapamulin-Assisted Rib osome Profiling Reveals the Alternative Bacterial Proteome Graphical

D. Klepacki, P. Baranov, A. Mankin, 2019 .

EmtA, a rRNA methyltransferase conferring high‐level evernimicin resistance

F. Aarestrup, A. Mankin, R. Goering, 2001, Molecular microbiology.

Programmed Ribosomal Frameshifting Generates a Copper Transporter and a Copper Chaperone from the Same Gene.

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2017, Molecular cell.

23S rRNA positions essential for tRNA binding in ribosomal functional sites.

A. Mankin, M. Bocchetta, L. Xiong, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Ketolide Resistance Conferred by Short Peptides*

A. Mankin, S. Tripathi, P. Kloss, 1998, The Journal of Biological Chemistry.

Induction of erm(C) Expression by Noninducing Antibiotics

A. Mankin, Marne Bailey, T. Chettiath, 2008, Antimicrobial Agents and Chemotherapy.

Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2017, Nucleic acids research.

Kinetics of drug–ribosome interactions defines the cidality of macrolide antibiotics

A. Mankin, N. Vázquez-Laslop, M. Svetlov, 2017, Proceedings of the National Academy of Sciences.

Erythromycin Resistance Peptides Selected from Random Peptide Libraries*

A. Mankin, T. Tenson, L. Xiong, 1997, The Journal of Biological Chemistry.

Ribosomal and non‐ribosomal resistance to oxazolidinones: species‐specific idiosyncrasy of ribosomal alterations

A. Mankin, E. Böttger, P. Sander, 2002, Molecular microbiology.

Retapamulin-assisted ribosome profiling reveals the alternative bacterial proteome

D. Klepacki, P. Baranov, A. Mankin, 2019, bioRxiv.

Baby, don't stop!

A. Mankin, S. Liebman, 1999, Nature Genetics.

Discovery of Unannotated Small Open Reading Frames in Streptococcus pneumoniae D39 Involved in Quorum Sensing and Virulence Using Ribosome Profiling

A. Mankin, N. Vázquez-Laslop, M. Federle, 2022, mBio.

Transcriptional and Translational Control of the mlr Operon, Which Confers Resistance to Seven Classes of Protein Synthesis Inhibitors (cid:1)

A. Mankin, L. K. Smith, 2008 .

Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly

D. Klepacki, L. Jaeger, A. Mankin, 2020, Nature Communications.

Dynamics of the context-specific translation arrest by chloramphenicol and linezolid

J. Puglisi, Dong-Hua Chen, A. Mankin, 2019, Nature Chemical Biology.

Vectors for cloning and activity determination of the elements of the bacterial transcription system: Cloning the transcription terminator of the rRNA operon of the archaebacterium Halobacterium halobium

A. Mankin, Y. Khudyakov, Skripkin Ea, 1987 .

Macrolide Antibiotics: Binding Site, Mechanism of Action, Resistance

A. Mankin, Marne Gaynor, 2005 .

Peptidyl transferase activity catalyzed by protein-free 23S ribosomal RNA remains elusive.

P. Khaitovich, R. Green, A. Mankin, 1999, RNA.

Genetic Environment and Stability of cfr in Methicillin-Resistant Staphylococcus aureus CM05

A. Mankin, Jeffrey B Locke, K. Shaw, 2011, Antimicrobial Agents and Chemotherapy.

Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.

A. Mankin, P. Sergiev, A. Konevega, 2018, Journal of molecular biology.

Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis

D. Klepacki, J. Cate, A. Mankin, 2010, Antimicrobial Agents and Chemotherapy.

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

J. Cate, A. Mankin, J. Dunkle, 2010, Proceedings of the National Academy of Sciences.

Crystal structure of the E. coli ribosome bound to telithromycin.

J. Cate, A. Mankin, J. Dunkle, 2014 .

The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre.

R. Garrett, B. Porse, A. Mankin, 1998, Journal of molecular biology.

Identification of ten additional nucleotides in the primary structure of yeast 18S rRNA.

A. Mankin, K. Skryabin, P. Rubtsov, 1986, Gene.

Macrolide antibiotics: binding site, mechanism of action, resistance.

A. Mankin, Marne Gaynor, 2003, Current topics in medicinal chemistry.

How Macrolide Antibiotics Work.

A. Mankin, N. Vázquez-Laslop, 2018, Trends in biochemical sciences.

Cross-linking in the Living Cell Locates the Site of Action of Oxazolidinone Antibiotics*

A. Mankin, J. Colca, W. Mathews, 2003, Journal of Biological Chemistry.

Binding Site of Macrolide Antibiotics on the Ribosome: New Resistance Mutation Identifies a Specific Interaction of Ketolides with rRNA

A. Mankin, G. Garza-Ramos, L. Xiong, 2001, Journal of bacteriology.

The Ribosomal Peptidyl Transferase Center: Structure, Function, Evolution, Inhibition

A. Mankin, N. Polacek, Norbert Polacek, 2005, Critical reviews in biochemistry and molecular biology.

Engineered ribosomes with tethered subunits for expanding biological function

Erik D. Carlson, Do Soon Kim, A. Mankin, 2019, Nature Communications.

Protein synthesis by ribosomes with tethered subunits

Michael C. Jewett, Erik D. Carlson, Cédric Orelle, 2015, Nature.

A synthetic antibiotic class overcoming bacterial multidrug resistance

D. Klepacki, A. Mankin, Y. Polikanov, 2021, Nature.

A fully orthogonal system for protein synthesis in bacterial cells

A. Mankin, N. Vázquez-Laslop, M. Jewett, 2020, Nature Communications.

Nucleotide Biosynthesis Is Critical for Growth of Bacteria in Human Blood

A. Mankin, Alexander S Mankin, Juan Chen, 2008, PLoS pathogens.

Acquisition of a natural resistance gene renders a clinical strain of methicillin‐resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid

J. Quinn, A. Mankin, C. Arias, 2007, Molecular microbiology.

Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible

A. Mankin, N. Vázquez-Laslop, Shanmugapriya Sothiselvam, 2013, Nature Communications.

An enzymatic approach for localization of oligodeoxyribonucleotide binding sites on RNA

A. Mankin, A. Bogdanov, N. Chichkova, 1981, FEBS letters.

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides

S. Douthwaite, A. Mankin, N. Vázquez-Laslop, 2015, Proceedings of the National Academy of Sciences.

Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan

Emily R. Gordon, C. Yanofsky, D. Klepacki, 2013, Nucleic acids research.

An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

Daniel N. Wilson, D. Klepacki, M. Graf, 2017, Nature Structural &Molecular Biology.

The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation

D. Klepacki, C. Gross, A. Mankin, 2022, Proceedings of the National Academy of Sciences.

Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.

T. Steitz, A. Mankin, N. Vázquez-Laslop, 2014, Molecular cell.

Nucleotide sequence of the 3'-terminal tRNA-like structure in barley stripe mosaic virus genome.

V. Dolja, A. Mankin, Morozov SYu, 1984, Nucleic acids research.

Inhibition of ribonuclease contamination in preparations of T4 RNA ligase, polynucleotide kinase, and bacterial alkaline phosphatase with bentonite.

A. Mankin, L. G. Tyulkina, 1984, Analytical biochemistry.

Synthesis and antibacterial activity of desosamine-modified macrolide derivatives.

D. Klepacki, A. Mankin, A. Melman, 2012, Bioorganic & medicinal chemistry letters.

Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2022, Nature Structural & Molecular Biology.

Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

A. Mankin, N. Vázquez-Laslop, J. Fraser, 2021, bioRxiv.

Structural signatures of antibiotic binding sites on the ribosome

Y. Mandel-Gutfreund, A. Mankin, Hilda David-Eden, 2010, Nucleic acids research.

The Genetic Environment of the cfr Gene and the Presence of Other Mechanisms Account for the Very High Linezolid Resistance of Staphylococcus epidermidis Isolate 426-3147L

Ronald N. Jones, A. Mankin, S. Schwarz, 2012, Antimicrobial Agents and Chemotherapy.

Specific fragmentation of tRNA and rRNA at a 7-methylguanine residue in the presence of methylated carrier RNA.

A. Mankin, A. Bogdanov, L. Baratova, 1985, European journal of biochemistry.

Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center

K. Kannan, D. Klepacki, A. Mankin, 2016, Proceedings of the National Academy of Sciences.

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

A. Mankin, N. Polacek, A. Yassin, 2001, Nature.

A functional peptide encoded in the Escherichia coli 23S rRNA.

A. Deblasio, A. Mankin, T. Tenson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Introducing mutations into the single-copy chromosomal 23S rRNA gene of the archaeon Halobacterium halobium by using an rRNA operon-based transformation system.

R. Garrett, A. Mankin, I. Zyrianova, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of functionally active subribosomal particles from Thermus aquaticus.

P. Khaitovich, H. Noller, R. Green, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of gene expression by macrolide-induced ribosomal frameshifting.

K. Kannan, A. Mankin, N. Vázquez-Laslop, 2013, Molecular cell.

Regulationof Gene Expression byMacrolide-Induce dRibosomal Frameshifting

K. Kannan, A. Mankin, N. Vázquez-Laslop, 2013 .

Archaeal rRNA operons.

R. Garrett, N. Larsen, J. Kjems, 1991, Trends in biochemical sciences.

Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.

A. Mankin, G. Atkinson, M. Svetlov, 2020, Nature Chemical Biology.

An rRNA Fragment and Its Antisense Can Alter Decoding of Genetic Information

A. Mankin, E. J. Murgola, A. Arkov, 1998, Journal of bacteriology.

Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site.

A. Mankin, J. Bolla, C. Cotteaux-Lautard, 2018, Molecular cell.

Major Families of Multiresistant Plasmids from Geographically and Epidemiologically Diverse Staphylococci

J. Gill, Jon Borman, A. Mankin, 2011, G3: Genes | Genomes | Genetics.

Antibiotics and the ribosome

A. Mankin, T. Tenson, 2006, Molecular microbiology.

Context-specific action of macrolide antibiotics on the eukaryotic ribosome

Daniel N. Wilson, D. Klepacki, N. Guydosh, 2021, Nature Communications.

The general mode of translation inhibition by macrolide antibiotics

David W. Schryer, Pinal N. Kanabar, K. Kannan, 2014, Proceedings of the National Academy of Sciences.

Macrolide antibiotics allosterically predispose the ribosome for translation arrest

Klaus Schulten, Maido Remm, Gemma Catherine Atkinson, 2014, Proceedings of the National Academy of Sciences.

Macrolide antibiotics in the ribosome exit tunnel: species‐specific binding and action

K. Kannan, A. Mankin, 2011, Annals of the New York Academy of Sciences.

Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition

Raktim N. Roy, T. Steitz, A. Mankin, 2016, Nucleic acids research.

Antibacter ial Agents that Cause Miscoding by Binding at a New Ribosomal Site Graphical Abstract Highlights

A. Mankin, J. Bolla, C. Cotteaux-Lautard, 2022 .

MicroReview Programmed drug-dependent ribosome stalling

H. Ramu, A. Mankin, N. Vázquez-Laslop, 2009 .

Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.

A. Mankin, L. Xiong, D. Shinabarger, 1999, Journal of molecular biology.

Oxazolidinone Resistance Mutations in 23S rRNA ofEscherichia coli Reveal the Central Region of Domain V as the Primary Site of Drug Action

S. Douthwaite, A. Mankin, S. Swaney, 2000, Journal of bacteriology.

Effect of antibiotics on large ribosomal subunit assembly reveals possible function of 5 S rRNA.

P. Khaitovich, A. Mankin, 1999, Journal of molecular biology.

Selective Protein Synthesis by Ribosomes with a Drug-Obstructed Exit Tunnel

K. Kannan, A. Mankin, N. Vázquez-Laslop, 2012, Cell.

Triggering peptide-dependent translation arrest by small molecules: Ribosome stalling modulated by antibiotics

A. Mankin, N. Vázquez-Laslop, 2014 .

Comparison of functional peptide encoded in the Escherichia coli 23S rRNA with other peptides involved in cis-regulation of translation.

A. Mankin, T. Tenson, 1995, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Mechanism of translation inhibition by type II GNAT toxin AtaT2

A. Mankin, N. Vázquez-Laslop, P. Sergiev, 2020, Nucleic acids research.

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2013, Nucleic acids research.

Context‐specific action of ribosomal antibiotics

A. Mankin, N. Vázquez-Laslop, 2017, Annual review of microbiology.

Nascent peptide assists the ribosome in recognizing chemically distinct small molecules

K. Schulten, D. Klepacki, A. Mankin, 2016, Nature chemical biology.

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

K. Kannan, D. Klepacki, H. Ramu, 2010, The EMBO journal.

The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.

A. Mankin, K. Leach, J. Colca, 2007, Molecular cell.

Low Fitness Cost of the Multidrug Resistance Gene cfr

A. Mankin, Jeffrey B Locke, K. Shaw, 2011, Antimicrobial Agents and Chemotherapy.

Identifying Small Open Reading Frames in Prokaryotes with Ribosome Profiling

Allen R. Buskirk, A. Mankin, N. Vázquez-Laslop, 2021 .

Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size.

D. Klepacki, R. Micura, A. Mankin, 2016, Cell reports.

Protein Accounting in the Cellular Economy

A. Mankin, N. Vázquez-Laslop, 2014, Cell.

Context-based sensing of orthosomycin antibiotics by the translating ribosome

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2022, Nature Chemical Biology.

Identification of Translation Start Sites in Bacterial Genomes.

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2021, Methods in molecular biology.

Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2020, eLife.

Assembly and functionality of the ribosome with tethered subunits

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2019, Nature Communications.

Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

Daniel N. Wilson, H. Ramu, A. Mankin, 2014, Nature Communications.

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics

Daniel N. Wilson, H. Grubmüller, M. Graf, 2021, Nature Communications.

Tools for Characterizing Bacterial Protein Synthesis Inhibitors

A. Mankin, C. Orelle, C. Squires, 2013, Antimicrobial Agents and Chemotherapy.

Molecular mechanism of drug-dependent ribosome stalling.

A. Mankin, N. Vázquez-Laslop, Alexander S Mankin, 2008, Molecular cell.

Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

Debbie C. Mulhearn, D. Klepacki, H. Ramu, 2011, Proceedings of the National Academy of Sciences.

Genes within Genes in Bacterial Genomes

A. Mankin, N. Vázquez-Laslop, Sezen Meydan, 2018, Regulating with RNA in Bacteria and Archaea.

Genes within Genes in Bacterial Genomes.

A. Mankin, N. Vázquez-Laslop, Sezen Meydan, 2018, Microbiology spectrum.

Complete nucleotide sequence of the single ribosomal RNA operon of Halobacterium halobium: secondary structure of the archaebacterial 23S rRNA

A. Mankin, V. K. Kagramanova, 2004, Molecular and General Genetics MGG.

Heterogeneity of small plasmids from halophilic archaea

A. Mankin, A. Akhmanova, V. K. Kagramanova, 1993, Journal of bacteriology.

The nucleotide sequence of the genes coding for the S19 and L22 equivalent ribosomal proteins from Halobacterium halobium

A. Mankin, 1989, FEBS letters.

A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria

A. Mankin, N. Vázquez-Laslop, M. Svetlov, 2020, Proceedings of the National Academy of Sciences.

The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics

D. Klepacki, A. Mankin, A. Bashan, 2010, Proceedings of the National Academy of Sciences.

Macrolide myths.

A. Mankin, Alexander S Mankin, 2008, Current opinion in microbiology.

Interactions between 23S rRNA and tRNA in the ribosomal E site.

A. Mankin, M. Bocchetta, L. Xiong, 2001, RNA.

Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome.

A. Mankin, C. Li, S. Liebman, 2000, RNA.

Picky nascent peptides do not talk to foreign ribosomes

A. Mankin, N. Vázquez-Laslop, 2011, Proceedings of the National Academy of Sciences.

Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics.

Kurt Fredrick, A. Mankin, K. Fredrick, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Potential New Antibiotic Sites in the Ribosome Revealed by Deleterious Mutations in RNA of the Large Ribosomal Subunit*

A. Mankin, A. Yassin, Aymen S. Yassin, 2007, Journal of Biological Chemistry.

Ribosomal Antibiotics

A. Mankin, 2004, Molecular Biology.

Chloramphenicol resistance mutations in the single 23S rRNA gene of the archaeon Halobacterium halobium

R. Garrett, A. Mankin, Roger A. Garrett, 1991, Journal of bacteriology.

Transcriptional and Translational Control of the mlr Operon, Which Confers Resistance to Seven Classes of Protein Synthesis Inhibitors

A. Mankin, L. K. Smith, 2008, Antimicrobial Agents and Chemotherapy.

Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.

T. Steitz, M. Rodnina, A. Mankin, 2014, Molecular cell.

Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding.

H. Noller, A. Mankin, R. Hickerson, 2009, RNA.

SPARK--a novel method to monitor ribosomal peptidyl transferase activity.

A. Mankin, N. Polacek, S. Swaney, 2002, Biochemistry.

Inhibition of Translation and Cell Growth by Minigene Expression

A. Mankin, T. Tenson, G. Guarneros, 1999, Journal of bacteriology.

The nucleotide sequence of the gene coding for the 16S rRNA from the archaebacterium Halobacterium halobium.

A. Mankin, A. Bogdanov, N. Teterina, 1985, Gene.

RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA.

J. Wiesner, H. Jomaa, A. Mankin, 2010, Journal of the American Chemical Society.

MicroReview Antibiotics and the ribosome

A. Mankin, T. Tenson, 2006 .

Essential Mechanisms in the Catalysis of Peptide Bond Formation on the Ribosome*

Malte Beringer, Peter Bieling, M. Rodnina, 2005, Journal of Biological Chemistry.

Binding Site of the Bridged Macrolides in the Escherichia coli Ribosome

A. Mankin, Y. Korkhin, L. Xiong, 2005, Antimicrobial Agents and Chemotherapy.

Halobacterium halobium . single 23 S rRNA gene of the archaeon Chloramphenicol resistance mutations in the

R. Garrett, A. Mankin, 2003 .

Modification of 18 S rRNA in the 40 S ribosomal subunit of yeast with dimethyl sulfate

A. Mankin, A. Bogdanov, A. Kopylov, 1981, FEBS letters.

Charting the sequence-activity landscape of peptide inhibitors of translation termination

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2021, Proceedings of the National Academy of Sciences.

A novel site of antibiotic action in the ribosome: Interaction of evernimicin with the large ribosomal subunit

A. Mankin, T. Tenson, P. McNicholas, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Pactamycin resistance mutations in functional sites of 16 S rRNA.

A. Mankin, A S Mankin, Alexander S. Mankin, 1997, Journal of molecular biology.

Synthesis Inhibitors Tools for Characterizing Bacterial Protein

A. Mankin, C. Orelle, C. Squires, 2014 .

An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors.

A. Mankin, Seok-Ming Toh, 2008, Journal of molecular biology.

Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center.

D. Klepacki, R. Micura, J. Piccirilli, 2011, Molecular cell.

Nascent peptide-mediated ribosome stalling promoted by antibiotics

H. Ramu, A. Mankin, N. Vázquez-Laslop, 2011 .

Erm 39 L MSVTYIRLRIT ErmXL MLISGTAFLRLRTNRKAFPTP ErmQL MIMNGGIASIRLRR EreAL MTPNNSFKPTPLRGAA ErmFL MKTPTGLSGSISQRVRTLVK ErmWL MGFSFTGSAFIRLRTA Miscellaneous peptides ErmBL MLVFQMRNVDKTSTVLKQT KNSDYADK MefBL MYLIFM ErmGL

H. Ramu, A. Mankin, N. Vázquez-Laslop, 2011 .

Erythromycin- and Chloramphenicol-Induced Ribosomal Assembly Defects Are Secondary Effects of Protein Synthesis Inhibition

A. Mankin, T. Tenson, J. Remme, 2008, Antimicrobial Agents and Chemotherapy.

A fully orthogonal system for protein synthesis in bacterial cells

A. Mankin, N. Vázquez-Laslop, M. Jewett, 2020, Nature Communications.

Molecular Mechanisms of Antibiotic Action on the Ribosome

A. Mankin, 2014 .

Occurrence and location of 7‐methylguanine residues in small‐subunit ribosomal RNAs from eubacteria, archaebacteria and eukaryotes

A. Mankin, A. Bogdanov, R. Zimmermann, 1985 .

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

A. Mankin, N. Polacek, Koichi Ito, 2003, Molecular cell.

Inhibition of translation termination by Drosocin, an antimicrobial peptide from fruit flies

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2022, bioRxiv.

Inhibition of translation termination by the antimicrobial peptide Drosocin

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2023, Nature Chemical Biology.

A protein component at the heart of an RNA machine: the importance of protein l27 for the function of the bacterial ribosome.

H. Ramu, A. Mankin, Alexander S Mankin, 2005, Molecular cell.

Reconstitution of the 50S Subunit with In Vitro-Transcribed 23S rRNA: a New Tool for Studying Peptidyltransferase

P. Khaitovich, A. Mankin, 2000 .

Suppression of Nonsense Mutations Induced by Expression of an RNA Complementary to a Conserved Segment of 23S rRNA

A. Mankin, E. J. Murgola, Natalya S. Chernyaeva, 1999, Journal of bacteriology.

Nascent peptide in the "birth canal" of the ribosome.

A. Mankin, Alexander S Mankin, 2006, Trends in biochemical sciences.

Chemical engineering of the peptidyl transferase center reveals an important role of the 2′-hydroxyl group of A2451

R. Micura, A. Hüttenhofer, A. Mankin, 2005, Nucleic acids research.

SPARK: a new peptidyl transferase activity assay.

A. Mankin, N. Polacek, 2008, Methods in Molecular Medicine.

Ribosomal protein gene cluster of Halobacterium halobium: nucleotide sequence of the genes coding for S3 and L29 equivalent ribosomal proteins.

A. Mankin, A. Akhmanova, V. Spiridonova, 1989, Canadian journal of microbiology.

Inducible Resistance to Macrolide Antibiotics

H. Ramu, A. Mankin, S. L. Subramanian, 2012 .

Short peptides conferring resistance to macrolide antibiotics

A. Mankin, T. Tenson, 2001, Peptides.

The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.

A. Mankin, T. Bae, L. Xiong, 2007, RNA.

Antibiotic blocks mRNA path on the ribosome

A. Mankin, 2006, Nature Structural &Molecular Biology.

Reconstitution of functionally active Thermus aquaticus large ribosomal subunits with in vitro-transcribed rRNA.

P. Khaitovich, A. Mankin, T. Tenson, 1999, Biochemistry.

Peptide‐mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel

A. Mankin, T. Tenson, V. Vimberg, 2004, Molecular microbiology.

A conserved secondary structural motif in 23S rRNA defines the site of interaction of amicetin, a universal inhibitor of peptide bond formation.

H. Noller, R. Garrett, A. Mankin, 1994, The EMBO journal.

Stable Maintenance in Halobacteria of Plasmids Harboring rDNA

R. Garrett, P. Forterre, A. Mankin, 1993 .

Cross-hypersensitivity effects of mutations in 23 S rRNA yield insight into aminoacyl-tRNA binding.

R. Garrett, A. Mankin, I. Leviev, 1994, Journal of molecular biology.

A putative internal promoter in the 16 S/23 S intergenic spacer of the rRNA operon of archaebacteria and eubacteria

A. Mankin, E. Skripkin, V. K. Kagramanova, 1987, FEBS letters.

The 3'‐terminal nucleotide sequence of the Halobacterium halobium 16 S rRNA

A. Mankin, A. Bogdanov, L. Baratova, 1982, FEBS letters.

Selection of small peptides, inhibitors of translation.

D. Klepacki, A. Mankin, B. Llano-Sotelo, 2009, Journal of molecular biology.

Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance.

S. Douthwaite, A. Mankin, T. Tenson, 1996, Journal of molecular biology.

Nosocomial superinfections due to linezolid-resistant Enterococcus faecalis: evidence for a gene dosage effect on linezolid MICs.

J. Quinn, A. Mankin, P. Schreckenberger, 2003, Diagnostic microbiology and infectious disease.

Role of antibiotic ligand in nascent peptide-dependent ribosome stalling

D. Klepacki, H. Ramu, A. Mankin, 2011, Proceedings of the National Academy of Sciences.

Molecular mechanism of drug-dependent ribosome stalling.

A. Mankin, N. Vázquez-Laslop, Celine Thum, 2008, Molecular cell.

Protein synthesis by ribosomes with tethered subunits

Erik D. Carlson, A. Mankin, M. Jewett, 2015, Nature.

Complex promoter pattern of the single ribosomal RNA operon of an archaebacterium Halobacterium halobium.

A. Mankin, A S Mankin, V K Kagramanova, 1988, Nucleic acids research.

Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation.

G. Tan, A. Mankin, Alexandra DeBlasio, 1996, Journal of molecular biology.

Peptidyl-tRNA hydrolase is the nascent chain release factor in bacterial ribosome-associated quality control.

A. Mankin, N. Vázquez-Laslop, G. Atkinson, 2023, Molecular cell.

Structure-Activity Relationships of the Antimicrobial Peptide Natural Product Apidaecin.

D. Klepacki, A. Mankin, Y. Polikanov, 2023, Journal of medicinal chemistry.

Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

D. Klepacki, A. Mankin, N. Vázquez-Laslop, 2022, Nature Structural & Molecular Biology.

The complete nucleotide sequence of the arcaebacterial plasmid pHSB from Halobacterium, strain SB3.

A. Mankin, V. K. Kagramanova, N. I. Derckacheva, 1988, Nucleic acids research.

Peptidyl transferase activity catalyzed by protein-free 23S ribosomal RNA remains elusive.

A. Mankin, T. Tenson, Philipp Khaitovich, 1999, RNA.

Identifying Small Open Reading Frames in Prokaryotes with Ribosome Profiling

Allen R. Buskirk, A. Mankin, N. Vázquez-Laslop, 2021, Journal of bacteriology.