J. McFadden

J. McFadden, Z. Zwolska, A. Sajduda, 1998, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Loss of phenotypic inheritance associated with ydcI mutation leads to increased frequency of small, slow persisters in Escherichia coli

W. Jacobs, J. McFadden, H. Tang, 2020, Proceedings of the National Academy of Sciences.

Slow Protein Fluctuations Explain the Emergence of Growth Phenotypes and Persistence in Clonal Bacterial Populations

A. Kierzek, J. McFadden, A. Rocco, 2013, PloS one.

Dissecting Host-Pathogen Interactions in TB Using Systems-Based Omic Approaches

J. McFadden, Khushboo Borah, Ye Xu, 2021, Frontiers in Immunology.

Immunogenicity of Mycobacterium bovis BCG expressing Anaplasma marginale MSP1a antigen.

J. McFadden, F. Conceição, Â. Moreira, 2006, Vaccine.

Biologically distinct subtypes of Mycobacterium avium differ in possession of insertion sequence IS901

J. McFadden, Z. M. Kunze, F. Portaels, 1992, Journal of clinical microbiology.

Cellular localization, accumulation and trafficking of double-walled carbon nanotubes in human prostate cancer cells

S. R. Silva, J. McFadden, V. Neves, 2012, Nano Research.

The magnetic immuno‐polymerase chain reaction assay for the detection of Campylobacter in milk and poultry

J. McFadden, M. Adams, P. Patel, 1996, Letters in applied microbiology.

Detection of C. jejuni in Milk and Poultry Using the Magnetic Immuno-Polymerase Chain Reaction Assay

J. McFadden, M. Adams, P. Patel, 1996 .

Gene replacement by homologous recombination in Mycobacterium bovis BCG

J. McFadden, J. W. Dale, O. Dellagostin, 1995, Molecular microbiology.

Use of highly specific DNA probes and the polymerase chain reaction to detect Mycobacterium paratuberculosis in Johne's disease

J. McFadden, J. Hermon-Taylor, P. Vary, 1990, Journal of clinical microbiology.

An overview of human leptospirosis vaccine design and future perspectives

J. McFadden, A. McBride, C. Felix, 2019, Expert opinion on drug discovery.

Chloroquine-enhanced gene delivery mediated by carbon nanotubes

S. R. Silva, J. McFadden, C. Tîlmaciu, 2011 .

Towards the Immunoproteome of Neisseria meningitidis

J. McFadden, Celia L. McNeilly, T. Mendum, 2009, PloS one.

Audit of prenatal diagnosis for haemoglobin disorders in the United Kingdom: the first 20 years

J. McFadden, J. Newcombe, Cartwright Kav, 1997 .

Epidemiological and genetic markers, virulence factors and intracellular growth of Mycobacterium avium in AIDS.

Nalin Rastogi, J. McFadden, Z. M. Kunze, 1992, Research in microbiology.

DNA PROBES DEMONSTRATE A SINGLE HIGHLY CONSERVED STRAIN OF MYCOBACTERIUM AVIUM INFECTING AIDS PATIENTS

J. McFadden, J. Hermon-Taylor, M. Moss, 1989, The Lancet.

IS900‐promoted stable integration of a foreign gene into mycobacteria

J. McFadden, S. Wall, P. M. England, 1991, Molecular microbiology.

Strain variation in Mycobacterium avium: Polymorphism of IS1110-related sequences☆

J. McFadden, Z. M. Kunze, M. Yakrus, 1997 .

Polymerase chain reaction for diagnosis of meningococcal meningitis

J. McFadden, W. Palmer, K. Cartwright, 1992, The Lancet.

DNA/RNA purified single walled carbon nanotubes on self-assembled networks

E. Mendoza, J. McFadden, S. R. P. Silva, 2005 .

Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis

V. T. Forsyth, S. Noack, J. McFadden, 2021, Molecular systems biology.

Stimulation of transposition of the Mycobacterium tuberculosis insertion sequence IS6110 by exposure to a microaerobic environment

J. McFadden, A. McBride, O. Dellagostin, 1999, Molecular microbiology.

IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex.

J. McFadden, J. Dziadek, J. W. Dale, 1998, Microbiology.

Molecular biology of the mycobacteria

J. McFadden, 1990 .

Determination of genome size and DNA homology between an unclassified Mycobacterium species isolated from patients with Crohn's disease and other mycobacteria.

J. McFadden, P. Butcher, R. Chiodini, 1987, Journal of general microbiology.

The electrophoretic analysis of low molecular weight nucleic acids from Crohn's disease tissues in the search for an unconventional small infections agent

J. McFadden, P. Butcher, J. Hermon-Taylor, 2005, Archives of Virology.

Metabolic flux partitioning between the TCA cycle and glyoxylate shunt combined with a reversible methyl citrate cycle provide nutritional flexibility for Mycobacterium tuberculosis

V. T. Forsyth, J. McFadden, Nathaniel D Hawkins, 2021, bioRxiv.

Infrequent Transmission of Double-stranded RNA Virus Particles but Absence of DNA Proviruses in Single Ascospore Cultures of Gaeumannomyces graminis

J. McFadden, K. Buck, C. Rawlinson, 1983 .

Identification of spheroplast-like agents isolated from tissues of patients with Crohn's disease and control tissues by polymerase chain reaction

J. McFadden, Z. M. Kunze, R. Chiodini, 1993, Journal of clinical microbiology.

Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge

J. McFadden, E. Miyaji, B. Gicquel, 2004, Infection and Immunity.

Immunoprecipitation of antigen-associated [32P]-labelled nucleic acids from Crohn's disease mesenteric lymph nodes.

J. McFadden, P. Butcher, J. Hermon-Taylor, 1985, British journal of experimental pathology.

Intracellular Mycobacterium tuberculosis Exploits Multiple Host Nitrogen Sources during Growth in Human Macrophages

J. McFadden, D. Beste, A. Theorell, 2019, Cell reports.

A mixed nitrogen diet and compartmentalized utilization for Mycobacterium tuberculosis replicating in host cells: results of a systems-based analysis

J. McFadden, D. Beste, K. Nöh, 2019, bioRxiv.

Mutation in the P36 gene of Mycobacterium bovis provokes attenuation of the bacillus in a mouse model.

J. McFadden, A. Cataldi, F. Bigi, 2005, Tuberculosis.

Infection with an Avirulent phoP Mutant of Neisseria meningitidis Confers Broad Cross-Reactive Immunity

J. McFadden, S. Funnell, L. Eales-Reynolds, 2004, Infection and Immunity.

Sequence complexities of the nuclear and mitochondrial genomes of the take-all fungus, Gaeumannomyces graminis var. tritici.

J. McFadden, K. Buck, 1983, Journal of general microbiology.

Naturally occurring insertional inactivation of the porA gene of Neisseria meningitidis by integration of IS1301

J. McFadden, K. Cartwright, J. Newcombe, 1998, Molecular microbiology.

PCR-single-stranded confirmational polymorphism analysis for non-culture-based subtyping of meningococcal strains in clinical specimens

J. McFadden, W. Palmer, K. Cartwright, 1997, Journal of clinical microbiology.

PCR of peripheral blood for diagnosis of meningococcal disease

J. McFadden, W. Palmer, K. Cartwright, 1996, Journal of clinical microbiology.

Cellular localization , accumulation and trafficking of DWNTs in human prostate cancer cells

Heister, J. McFadden, C. Tîlmaciu, 2012 .

Spontaneous mutations conferring antibiotic resistance to antitubercular drugs at a range of concentrations in Mycobacterium smegmatis

J. McFadden, I. Nyinoh, 2018, bioRxiv.

Mycobacterial DNA not detected in liver sections from patients with primary biliary cirrhosis.

J. McFadden, K. Nouri-Aria, J. O'donohue, 1998, Journal of hepatology.

Challenges for the development of a universal vaccine against leptospirosis revealed by the evaluation of 22 vaccine candidates

J. McFadden, A. McBride, O. Dellagostin, 2022, Frontiers in cellular and infection microbiology.

Deletion of the putative antioxidant noxR1 does not alter the virulence of Mycobacterium tuberculosis H37Rv.

J. McFadden, G. Stewart, S. Ehrt, 2000, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Lactate-Induced Dispersal of Neisseria meningitidis Microcolonies Is Mediated by Changes in Cell Density and Pilus Retraction and Is Influenced by Temperature Change

J. McFadden, F. Zuo, J. Newcombe, 2021, Infection and immunity.

Mycobacterium bovis BCG as a delivery system for the RAP-1 antigen from Babesia bovis.

J. McFadden, B. Gicquel, A. Cataldi, 2007, Vaccine.

Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice.

J. McFadden, F. Conceição, J. W. Dale, 2001, Vaccine.

Higher dispersion efficacy of functionalized carbon nanotubes in chemical and biological environments.

Emmanuel Flahaut, Peter Hinterdorfer, Johnjoe McFadden, 2010, ACS nano.

Systems-Based Approaches to Probing Metabolic Variation within the Mycobacterium tuberculosis Complex

Andrzej M. Kierzek, Paul R. Wheeler, Johnjoe McFadden, 2013, PloS one.

Quadruple antimycobacterial chemotherapy in Crohn's disease: results at 9 months of a pilot study in 20 patients

J. McFadden, J. Hermon-Taylor, A. Joseph, 1989, Alimentary pharmacology & therapeutics.

No evidence for antibodies to mycobacterial A60 antigen in Crohn's disease sera by enzyme-linked immunoabsorbent assay (ELISA).

J. McFadden, C. Houdayer, 1988, Journal of medical microbiology.

Crohn's disease-isolated mycobacteria are identical to Mycobacterium paratuberculosis, as determined by DNA probes that distinguish between mycobacterial species

J. McFadden, P. Butcher, R. Chiodini, 1987, Journal of clinical microbiology.

Identification of proteins from tuberculin purified protein derivative (PPD) by LC-MS/MS.

J. McFadden, S. Borsuk, O. Dellagostin, 2009, Tuberculosis.

Sequence and characteristics of IS900, an insertion element identified in a human Crohn's disease isolate of Mycobacterium paratuberculosis.

J. McFadden, M. Tizard, J. Hermon-Taylor, 1989, Nucleic acids research.

A standardized BioBrick toolbox for the assembly of sequences in mycobacteria.

J. McFadden, O. Dellagostin, T. Oliveira, 2019, Tuberculosis.

Polymerase chain reaction for detection of Mycobacterium leprae in nasal swab specimens

J. McFadden, P. Klatser, J. Douglas, 1993, Journal of clinical microbiology.

Polymerase ChainReaction forDetection ofMycobacterium leprae inNasalSwabSpecimens

J. McFadden, 1993 .

Activity of mycobacterial promoters during intracellular and extracellular growth.

J. McFadden, J. W. Dale, O. Dellagostin, 1995, Microbiology.

Construction and use of integrative vectors to express foreign genes in mycobacteria

J. McFadden, J. W. Dale, O. Dellagostin, 1993, Molecular microbiology.

Carbon flux rerouting during Mycobacterium tuberculosis growth arrest

Johnjoe McFadden, Pratik Datta, J. McFadden, 2010, Molecular microbiology.

Carbon flux rerouting during Mycobacterium tuberculosis growth

J. McFadden, P. Datta, M. Gennaro, 2010 .

Comparative evaluation of Mycobacterium vaccae as a surrogate cloning host for use in the study of mycobacterial genetics.

W. Degrave, J. McFadden, O. Dellagostin, 2002, Microbiology.

In vitro Transcription of Double-stranded RNA by Virion-associated RNA Polymerases of Viruses from Gaeumannomyces graminis

J. McFadden, K. Buck, M. Romanos, 1981 .

Detection of mycobacterial DNA in sarcoidosis and tuberculosis with polymerase chain reaction

J. McFadden, N. Johnson, S. Saboor, 1992, The Lancet.

Investigation of mycobacteria in Crohn's disease tissue by Southern blotting and DNA hybridisation with cloned mycobacterial genomic DNA probes from a Crohn's disease isolated mycobacteria.

J. McFadden, P. Butcher, J. Hermon-Taylor, 1988, Gut.

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

S. Noack, B. Bonde, J. McFadden, 2011, PLoS pathogens.

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

A. Kierzek, B. Bonde, J. McFadden, 2009, PloS one.

Mycobacteria and Crohn's disease.

J. McFadden, J. Hermon-Taylor, S. Hampson, 1988, Gut.

The use of cloned mycobacterial DNA probes for the detection of mycobacteria in Crohn's disease tissue

J. McFadden, P. Butcher, J. Hermon-Taylor, 1987 .

Use of DNA probes to identify and classify mycobacteria

J. McFadden, P. Butcher, J. Hermon-Taylor, 1987 .

Drug loading, dispersion stability, and therapeutic efficacy in targeted drug delivery with carbon nanotubes

S. Ravi P. Silva, Johnjoe McFadden, Helen M. Coley, 2012 .

A microfluidic system for long-term time-lapse microscopy studies of mycobacteria.

Johnjoe McFadden, J. McFadden, R. Curry, 2012, Tuberculosis.

Compiling a Molecular Inventory for Mycobacterium bovis BCG at Two Growth Rates: Evidence for Growth Rate-Mediated Regulation of Ribosome Biosynthesis and Lipid Metabolism

J. McFadden, C. Avignone-Rossa, M. Bushell, 2005, Journal of bacteriology.

Development of Loop-Mediated Isothermal Amplification Rapid Diagnostic Assays for the Detection of Klebsiella pneumoniae and Carbapenemase Genes in Clinical Samples

Aurore C. Poirier, J. Qu, J. McFadden, 2022, Frontiers in Molecular Biosciences.

Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice.

J. McFadden, P. Sequeira, L. Riley, 2008, Journal of medical microbiology.

Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis

Andrzej M. Kierzek, Emma Laing, Bhushan K. Bonde, 2011, PLoS Comput. Biol..

Carbon Nanotubes Loaded with Anticancer Drugs: A Platform for Multimodal Cancer Treatment

J. McFadden, V. Neves, E. Heister, 2011 .

MUFINS: multi-formalism interaction network simulator

Steffen Klamt, Hiroshi Matsuno, Jacek Sroka, 2016, npj Systems Biology and Applications.

Immunoprecipitation of Cell Surface Proteins from Gram-negative Bacteria.

J. McFadden, O. Dellagostin, J. Newcombe, 2017, Bio-protocol.

Stochastic Gene Expression in Bacterial Pathogens: A Mechanism for Persistence?

A. Kierzek, J. McFadden, A. Rocco, 2013 .

Identification of the immunoproteome of the meningococcus by cell surface immunoprecipitation and MS.

J. McFadden, Chuan-peng Ren, T. Mendum, 2014, Microbiology.

Genetic screening for the protective antigenic targets of BCG vaccination.

J. McFadden, H. Vordermeier, G. Stewart, 2020, Tuberculosis.

Properties of Thirteen Viruses and Virus Variants Obtained from Eight Isolates of the Wheat Take-All Fungus, Gaeumannomyces graminis var. tritici.

J. McFadden, K. Buck, M. Romanos, 1981 .

Rational design of diagnostic and vaccination strategies for tuberculosis.

J. McFadden, S. Borsuk, D. Ramos, 2012, The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.

Modeling the binding of peptides on carbon nanotubes and their use as protein and DNA carriers

J. McFadden, H. Coley, V. Sanz, 2012, Journal of Nanoparticle Research.

Functionalized Carbon Nanotubes for Gene Biodelivery

J. McFadden, H. Coley, Ravi P. Silva, 2011 .

Recombination in mycobacteria

J. McFadden, 1996, Molecular microbiology.

Trajectory energy minimization for cell growth tracking and genealogy analysis

Nan Ma, Yin Hu, Su Wang, 2017, Royal Society Open Science.

Reduced toxicity of lipo-oligosaccharide from a phoP mutant of Neisseria meningitidis: an in vitro demonstration

J. McFadden, S. McClean, L. Eales-Reynolds, 2006, Journal of endotoxin research.

Simple enzymic method for isolation of DNA from diverse bacteria

J. McFadden, J. L. Stanford, J. Hermon-Taylor, 1989 .

Strain typing of the Mycobacterium avium complex.

J. McFadden, N. Inglis, Johnjoe McFadden, 1999, The Journal of infection.

Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis

J. McFadden, R. Banerjee, G. Stewart, 2019, Scientific Reports.

Transcriptomic Analysis Identifies Growth Rate Modulation as a Component of the Adaptation of Mycobacteria to Survival inside the Macrophage

B. Bonde, J. McFadden, C. Avignone-Rossa, 2007, Journal of bacteriology.

The Acute-Phase Reactant C-Reactive Protein Binds to Phosphorylcholine-Expressing Neisseria meningitidis and Increases Uptake by Human Phagocytes

J. McFadden, J. Newcombe, R. Casey, 2008, Infection and Immunity.

Triple functionalisation of single-walled carbon nanotubes with doxorubicin, a monoclonal antibody, and a fluorescent marker for targeted cancer therapy

J. McFadden, V. Neves, E. Heister, 2009 .

Mycobacteria and AIDS: epidemiological and genetic markers, virulence factors and interactions with the immune system.

Nalin Rastogi, J. McFadden, 1992, Research in microbiology.

Updating and curating metabolic pathways of TB.

Neema Jamshidi, Jeremy Zucker, Ron Caspi, 2013, Tuberculosis.

Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

J. McFadden, R. Banerjee, H. Vordermeier, 2019, BMC Genomics.

The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

J. McFadden, D. Beste, J. Ward, 2018, The Journal of Biological Chemistry.

13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

Wolfgang Wiechert, Katharina Nöh, Sebastian Niedenführ, 2013, Chemistry & biology.

GSMN-ML- a genome scale metabolic network reconstruction of the obligate human pathogen Mycobacterium leprae

R. Joshi, B. Bonde, J. McFadden, 2019, bioRxiv.

Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells

J. McFadden, D. Beste, M. C. Pessolani, 2019, mBio.

Effects of electromagnetic fields on neuronal ion channels: a systematic review

J. McFadden, S. R. P. Silva, K. Jeevaratnam, 2021, Annals of the New York Academy of Sciences.

Dysregulated NAD(H) homeostasis associated with ciprofloxacin tolerance in Escherichia coli investigated on a single-cell level with the Peredox [NADH:NAD+] biosensor

J. McFadden, F. Hai, S. Hingley-Wilson, 2023, Frontiers in Microbiology.

Carbon flux rerouting during Mycobacterium tuberculosis growth arrest

J. McFadden, P. Datta, M. Gennaro, 2016, Molecular microbiology.

One‐shot 13C15N‐metabolic flux analysis for simultaneous quantification of carbon and nitrogen flux

Michael C. Bailey, J. McFadden, D. Beste, 2023, Molecular systems biology.

Bayesian multi-model-based 13C15N-metabolic flux analysis quantifies carbon-nitrogen metabolism in mycobacteria

J. McFadden, D. Beste, K. Nöh, 2022, bioRxiv.

Uptake, Intracellular Localization and Biodistribution of Carbon Nanotubes

J. McFadden, V. Neves, H. Coley, 2011 .

Uptake and Release of Double‐Walled Carbon Nanotubes by Mammalian Cells

J. McFadden, V. Neves, E. Heister, 2010 .

Insight into proteomic investigations of Neisseria meningitidis serogroup C strain L91543 from analysis of its genome sequence.

Lori A. S. Snyder, J. McFadden, R. Griffin, 2015, FEMS microbiology letters.

Phenotypic and Transcriptional Characterization of the Meningococcal PhoPQ System, a Magnesium-Sensing Two-Component Regulatory System That Controls Genes Involved in Remodeling the Meningococcal Cell Surface

J. McFadden, J. Hinds, R. Stabler, 2005, Journal of bacteriology.

Antigen 43, the major phase-variable protein of the Escherichia coli outer membrane, can exist as a family of proteins encoded by multiple alleles.

J. McFadden, P. Owen, A. Roche, 2001, Microbiology.

Acorn: A grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks via a web interface

Dariusz Leniowski, Jacek Sroka, Jakub Lacki, 2011, BMC Bioinformatics.

New Recombinant Mycobacterium bovis BCG Expression Vectors: Improving Genetic Control over Mycobacterial Promoters

J. McFadden, L. Leite, S. Oliveira, 2016, Applied and Environmental Microbiology.

Phylogenetic and epidemiological analysis of Neisseria meningitidis using DNA probes

J. McFadden, K. Cartwright, A. Knight, 1992, Epidemiology and Infection.

Mycobacterium tuberculosis DNA in tissue affected by sarcoidosis.

J. McFadden, G. Rook, N. Johnson, 1993, BMJ.

IS901, a new member of a widespread class of atypical insertion sequences, is associated with pathogenicity in Mycobacterium avium

J. McFadden, R. Appelberg, Z. M. Kunze, 1991, Molecular microbiology.

Characterization of Mycobacterium avium complex related mycobacteria isolated from an African environment and patients with AIDS

J. McFadden, Z. M. Kunze, F. Portaels, 1997, Tropical medicine & international health : TM & IH.

Auxotrophic complementation as a selectable marker for stable expression of foreign antigens in Mycobacterium bovis BCG.

J. McFadden, S. Borsuk, O. Dellagostin, 2007, Tuberculosis.

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

S. Noack, B. Bonde, J. McFadden, 2011, PLoS Pathogens.

GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism

A. Kierzek, B. Bonde, P. Wheeler, 2007, Genome Biology.