J. Routy

J. Singer, V. Martel-Laferrière, C. Tremblay, 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Anti-cytomegalovirus Immunoglobulin G Is Linked to CD4 T-cell Count Decay in Human Immunodeficiency Virus (HIV) Elite Controllers

C. Tremblay, J. Routy, S. Isnard, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Plasma Levels of C-Type Lectin REG3α and Gut Damage in People With Human Immunodeficiency Virus Study, the Canadian Cohort of HIV+ Slow Progressors, the Canadian HIV and Aging Cohort Groups

J. Routy, I. Kema, S. Isnard, 2019 .

Evaluation of the human herpesvirus 8 DNA load in blood and Kaposi's sarcoma skin lesions from AIDS Patients on highly active antiretroviral therapy

J. Routy, G. Boivin, A. Gaudreau, 2000, AIDS.

HLA-DO increases bacterial superantigen binding to human MHC molecules by inhibiting dissociation of class II-associated invariant chain peptides.

J. Routy, A. Pezeshki, J. Thibodeau, 2013, Human immunology.

HLA‐DO transduced in human monocyte‐derived dendritic cells modulates MHC class II antigen processing

J. Routy, J. Thibodeau, R. Lapointe, 2005, Journal of leukocyte biology.

The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response

J. Routy, V. Mehraj, Rosalie Ponte, 2016, EBioMedicine.

Excess BAFF Alters NR4As Expression Levels and Breg Function of Human Precursor-like Marginal Zone B-Cells in the Context of HIV-1 Infection

D. Kaufmann, C. Tremblay, J. Routy, 2022, bioRxiv.

Cannabis Consumption in People Living with HIV: Reasons for Use, Secondary Effects, and Opportunities for Health Education.

J. Routy, M. Brouillette, Sara J. Abdallah, 2019, Cannabis and cannabinoid research.

Targeting the interleukin‐17 pathway to prevent acute respiratory distress syndrome associated with SARS‐CoV‐2 infection

J. Routy, P. Ancuta, B. Zheng, 2020, Respirology.

Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study

L. Lands, J. Routy, A. Shapiro, 2018, AIDS research and treatment.

Potential therapeutic options for coronavirus disease 2019: using knowledge of past outbreaks to guide future treatment

J. Routy, Yaokai Chen, S. Isnard, 2020, Chinese medical journal.

Influence of NKG2C Genotypes on HIV Susceptibility and Viral Load Set Point

C. Tremblay, D. Rouleau, J. Routy, 2021, Journal of virology.

and CD137L Responses by Dual Costimulation with CD80 Enhancement of HIV-Specific CD8 T Cell

M. Ostrowski, K. MacDonald, J. Routy, 2005 .

Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease

R. Wyatt, J. Billingsley, D. Kaufmann, 2019, Nature Immunology.

Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells

G. Freeman, D. Kaufmann, J. Routy, 2018, The Journal of Immunology.

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy

Lisa E. Wagar, M. Lederman, E. Kremmer, 2018, The Journal of Immunology.

Growth differentiation factor-15 as a biomarker of atherosclerotic coronary plaque: Value in people living with and without HIV

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2022, Frontiers in Cardiovascular Medicine.

Human Immunodeﬁciency Virus Type 1-Speciﬁc CD8 (cid:1) T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4 (cid:1) T Cells (cid:1) †

E. Rosenberg, H. Jessen, M. Altfeld, 2009 .

Time to Seroconversion in HIV-Exposed Subjects Carrying Protective versus Non Protective KIR3DS1/L1 and HLA-B Genotypes

Xianming Tan, J. Routy, J. Bruneau, 2014, PloS one.

Provir/Latitude 45 study: A step towards a multi-epitopic CTL vaccine designed on archived HIV-1 DNA and according to dominant HLA I alleles

M. Soares, C. Brander, M. Sajadi, 2019, PloS one.

Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study

M. Lederman, R. Sékaly, J. Routy, 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Intractable pleural effusion in Kaposi sarcoma following antiretroviral therapy in a Caucasian female infected with HIV

J. Routy, P. Fiset, P. Tajarernmuang, 2020, BMJ Case Reports.

Effect of Protease Inhibitor-Based Highly Active Antiretroviral Therapy on Survival in HIV-Associated Advanced Kaposi's Sarcoma Patients Treated with Chemotherapy

J. Routy, M. Trudeau, H. Leitch, 2003, HIV clinical trials.

Clinical outcome after lipectomy in the management of patients with human immunodeficiency virus-associated dorsocervical fat accumulation

J. Routy, Q. Cao, X. Gui, 2019, Medicine.

FoxP3+ CD8 T-cells in acute HIV infection and following early antiretroviral therapy initiation

C. Tremblay, J. Routy, C. Costiniuk, 2022, Frontiers in Immunology.

Oral abstracts of the 21st International AIDS Conference 18–22 July 2016, Durban, South Africa

Michael I. Jordan, Donald A. Jackson, J. G. Ndirangu, 2016, Journal of the International AIDS Society.

HTLV-1 Tax-Mediated Inhibition of FOXO3a Activity Is Critical for the Persistence of Terminally Differentiated CD4+ T Cells

J. van Grevenynghe, J. Routy, J. Hiscott, 2014, PLoS pathogens.

Memory CCR6CD4 T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin b7

J. Routy, P. Ancuta, N. Grandvaux, 2011 .

SARS-CoV-2 pre-exposure prophylaxis: A potential COVID-19 preventive strategy for high-risk populations, including healthcare workers, immunodeficient individuals, and poor vaccine responders

J. Routy, Yaokai Chen, J. Ouyang, 2022, Frontiers in Public Health.

A Novel and Simplified Method of Culture of Human Blood-Derived Early Endothelial Progenitor Cells for the Treatment of Ischemic Vascular Disease

A. Quyyumi, E. Schiffrin, J. Routy, 2011, Cell transplantation.

Human mesenchymal stromal cells transiently increase cytokine production by activated T cells before suppressing T-cell proliferation: effect of interferon-γ and tumor necrosis factor-α stimulation.

J. Routy, R. Romieu-Mourez, Y. Young, 2014, Cytotherapy.

Potential Role of Interleukin-18 in the Immunopathogenesis of AIDS: Involvement in Fratricidal Killing of NK Cells

C. Tremblay, J. Routy, A. Iannello, 2009, Journal of Virology.

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

D. Kaufmann, J. Routy, S. Crotty, 2017, PloS one.

Circulating β-D-Glucan as a marker of subclinical coronary plaque in ART-treated people living with HIV

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2021 .

Use of Smoking Cessation Aids in a Convenience Sample of PLHIV in a Canadian Tertiary Care Clinic

J. Routy, M. Brouillette, C. Costiniuk, 2019, The Open AIDS Journal.

A potentially protective role of IL‐18 Binding Protein in HIV‐infected Long‐Term Non‐Progressors

C. Tremblay, J. Routy, D. Amre, 2017, Cytokine.

HIV-1 causes an imbalance in the production of interleukin-18 and its natural antagonist in HIV-infected individuals: implications for enhanced viral replication.

C. Tremblay, J. Routy, A. Iannello, 2010, The Journal of infectious diseases.

Haemophagocytic lymphohistiocytosis in an adult with postacute COVID-19 syndrome

J. Routy, John Lin, G. Samoukovic, 2021, BMJ Case Reports.

Extracavitary primary effusion lymphoma recurring with syphilis in an HIV-infected patient

J. Routy, Darakhshan Sohail Ahmed, M. Poliquin, 2020, BMJ Case Reports.

Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells

J. van Grevenynghe, J. Routy, D. Avizonis, 2021, Autophagy.

Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

J. Routy, M. Ramgopal, R. Fromentin, 2020, Nature Communications.

Experiences of Migrant People Living with HIV in a Multidisciplinary HIV Care Setting with Rapid B/F/TAF Initiation and Cost-Covered Treatment: The ‘ASAP’ Study

J. Routy, G. Sebastiani, I. Vedel, 2022, Journal of personalized medicine.

LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy

J. Routy, J. Goulet, M. Massanella, 2021, EBioMedicine.

Cerebral aspergillosis and facial acneiform lesions following initiation of ibrutinib in a patient with chronic lymphocytic leukemia

J. Routy, John Lin, C. Frenette, 2021, IDCases.

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

J. Routy, R. Sékaly, C. Riou, 2013, The Journal of Immunology.

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

J. Routy, R. Sékaly, C. Riou, 2013, Journal of Immunology.

Human Herpesvirus 8 DNA Load in Leukocytes of Human Immunodeficiency Virus-Infected Subjects: Correlation with the Presence of Kaposi’s Sarcoma and Response to Anticytomegalovirus Therapy

M. Bergeron, J. Routy, G. Boivin, 1999, Antimicrobial Agents and Chemotherapy.

Plasma levels of C-type lectin REG3α and gut damage in people with HIV.

C. Tremblay, J. Routy, P. Lakatos, 2019, The Journal of infectious diseases.

This information is current as Molecules and Modulates T Cell Responses of Synthetic Peptides on MHC Class II Surface of Dendritic Cells Increases Loading Forced Expression of HLA-DM at the

J. Routy, A. Pezeshki, J. Thibodeau, 2011 .

Overcoming the challenge of diagnosis of early HIV infection: a stepping stone to optimal patient management

J. Routy, W. Cao, V. Mehraj, 2015, Expert review of anti-infective therapy.

Upregulation of IL-32 Isoforms in Virologically Suppressed HIV-Infected Individuals: Potential Role in Persistent Inflammation and Transcription From Stable HIV-1 Reservoirs.

S. Trottier, C. Tremblay, C. Chartrand-Lefebvre, 2019, Journal of acquired immune deficiency syndromes.

Two‐drug vs. three‐drug combinations for HIV‐1: Do we have enough data to make the switch?

J. Routy, S. Moreno, P. Corbeau, 2019, HIV medicine.

Impact of extended-release niacin on immune activation in HIV-infected immunological non-responders on effective antiretroviral therapy

J. Singer, J. Routy, M. Brouillette, 2020, HIV research & clinical practice.

The plasma levels of soluble ST2 as a marker of gut mucosal damage in early HIV infection

C. Tremblay, J. Routy, Réjean Thomas, 2016, AIDS.

New Th17-specific therapeutic strategies for HIV remission

J. Routy, D. Planas, P. Ancuta, 2019, Current opinion in HIV and AIDS.

Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function

G. Freeman, D. Kaufmann, C. Tremblay, 2021, bioRxiv.

Soluble CD40‐ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection

C. Tremblay, J. Routy, D. Radzioch, 2014, Clinical and experimental immunology.

Therapeutic Perspectives in the Systemic Treatment of Kaposi’s Sarcoma

J. Routy, S. Isnard, M. Valantin, 2022, Cancers.

Interleukin-7 promotes HIV persistence during antiretroviral therapy.

M. Lederman, J. Routy, R. Sékaly, 2013, Blood.

siRNA Knockdown of PD-L1 and PD-L2 in Monocyte-Derived Dendritic Cells only Modestly Improves Proliferative Responses to Gag by CD8+ T Cells from HIV-1-Infected Individuals

R. Steinman, J. Routy, R. Sékaly, 2009, Journal of Clinical Immunology.

Effects of drug resistance on viral load in patients failing antiretroviral therapy

M. Wainberg, J. Routy, Viet-An Nguyen, 2006, Journal of medical virology.

Increase of hemoglobin A2 in human immunodeficiency virus‐1‐infected patients treated with zidovudine

J. Routy, R. Beaulieu, E. Toma, 1993, American journal of hematology.

HIV-1 strains belonging to large phylogenetic clusters show accelerated escape from integrase inhibitors in cell culture compared with viral isolates from singleton/small clusters

M. Wainberg, B. Brenner, J. Routy, 2017, The Journal of antimicrobial chemotherapy.

The Relationship between Visceral Adiposity and Nonalcoholic Fatty Liver Disease Diagnosed by Controlled Attenuation Parameter in People with HIV: A Pilot Study

J. Routy, G. Sebastiani, G. Guaraldi, 2022, Diagnostics.

Subclinical Atherosclerosis Is Associated with Discrepancies in BAFF and APRIL Levels and Altered Breg Potential of Precursor-like Marginal Zone B-Cells in Long-Term HIV Treated Individuals

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2022, bioRxiv.

Impact of Autologous Dendritic Cell–Based Immunotherapy (AGS-004) on B- and T-Cell Subset Changes and Immune Activation in HIV-Infected Patients Receiving Antiretroviral Therapy

J. Routy, M. Debenedette, M. Jenabian, 2013, Journal of acquired immune deficiency syndromes.

MiRNA-103 downmodulates CCR5 expression reducing human immunodeficiency virus type-1 entry and impacting latency establishment in CD4+ T cells

Alon Herschhorn, C. Tremblay, J. Routy, 2022, iScience.

Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4+ T cells

J. Routy, J. Goulet, P. Ancuta, 2022, bioRxiv.

Cytomegalovirus Seropositivity Is Associated With Increased Microbial Translocation in People Living With Human Immunodeficiency Virus and Uninfected Controls

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients

J. Routy, I. Kema, C. Costiniuk, 2016, Journal of acquired immune deficiency syndromes.

Clinical characteristics and outcomes of chronic kidney disease in people living with HIV in a resource limited centre of central China.

J. Routy, Q. Cao, Juan Zhang, 2022, AIDS research and human retroviruses.

Assessing risk of a short‐term antiretroviral therapy discontinuation as a read‐out of viral control in immune‐based therapy

J. Routy, J. Jacobson, C. Nicolette, 2012, Journal of medical virology.

Role of Kynurenine Pathway in HIV/AIDS

J. Routy, V. Mehraj, K. Vyboh, 2015 .

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

J. Routy, J. Goulet, M. Massanella, 2020, Frontiers in Microbiology.

CXCL13 as a Biomarker of Immune Activation During Early and Chronic HIV Infection

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2019, Front. Immunol..

CXCL13 as a Biomarker of Immune Activation During Early and Chronic HIV Infection

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2019, Front. Immunol..

Multicentric Castleman's disease treated with combination chemotherapy and rituximab in four HIV‐positive men: A case series

J. Routy, R. Michel, C. Séguin, 2008, American journal of hematology.

Supplemental Information Host MicroRNAs-221 and-222 Inhibit HIV-1 Entry in Macrophages by Targeting the CD 4 Viral Receptor

Gilmore, J. Routy, C. Power, 2017 .

Circulating (1→3)-β-D-glucan Is Associated With Immune Activation During Human Immunodeficiency Virus Infection

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2020 .

Circulating (1→3)-β-D-Glucan is associated with immune activation during HIV infection.

V. Martel-Laferrière, C. Tremblay, C. Chartrand-Lefebvre, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Clinical outcome after lipectomy in the management of patients with human immunodeficiency virus-associated dorsocervical fat accumulation

J. Routy, Q. Cao, X. Gui, 2019, Medicine.

Immune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy

J. Routy, M. Jenabian, V. Mehraj, 2014, The open AIDS journal.

Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection

J. Routy, H. Cui, Yaokai Chen, 2023, Gut microbes.

The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis

J. Routy, A. Landay, V. Wacleche, 2017, Viruses.

Regulatory T Cells in HIV Infection: Can Immunotherapy Regulate the Regulator?

J. Routy, M. Jenabian, N. Gilmore, 2012, Clinical & developmental immunology.

Sharing CD4+ T Cell Loss: When COVID-19 and HIV Collide on Immune System

J. Routy, S. Isnard, John Lin, 2020, Frontiers in Immunology.

Use of (1→3)‐β‐d‐glucan for diagnosis and management of invasive mycoses in HIV‐infected patients

J. Routy, Hongzhou Lu, R. Ramendra, 2018, Mycoses.

HIV and the Gut Microbiota, Partners in Crime: Breaking the Vicious Cycle to Unearth New Therapeutic Targets

J. Routy, M. Jenabian, V. Mehraj, 2015, Journal of immunology research.

Arcelis AGS-004 dendritic cell-based immunotherapy for HIV infection.

J. Routy, C. Nicolette, 2010, Immunotherapy.

Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing

J. Routy, R. Cheynier, T. Guilbert, 2017, Front. Immunol..

Long-term immunosuppression with anti-CD25 monoclonal antibodies in heart transplant patients with chronic kidney disease.

J. Barkun, J. Routy, N. Giannetti, 2009, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

HIV Compartmentalization in Male Genital Tract: Relevance for Viral Eradication

J. Routy, S. Isnard, John Lin, 2021, Infectious Diseases & Immunity.

Proceedings of the Frontiers of Retrovirology Conference 2016

R. König, D. Elleder, R. Sachidanandam, 2016, Retrovirology.

Host cell polo ‐ like kinases ( PLKs ) promote early prototype foamy virus ( PFV ) replication

Mareike, Jochen, Yasuyuki, 2016 .

GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer

J. Routy, S. Isnard, John Lin, 2021, Journal of Cancer.

Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee.

D. Rouleau, J. Routy, N. Lapointe, 2011, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale.

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

R. Balderas, E. Delwart, J. Routy, 2006, Nature Medicine.

Diminished Representation of HIV-1 Variants Containing Select Drug Resistance-Conferring Mutations in Primary HIV-1 Infection

M. Wainberg, B. Brenner, D. Moisi, 2004, Journal of acquired immune deficiency syndromes.

Rationale for maintenance of the M184v resistance mutation in human immunodeficiency virus type 1 reverse transcriptase in treatment experienced patients.

M. Wainberg, B. Brenner, J. Routy, 2004, The new microbiologica.

CD4:CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV-positive patients

J. Routy, W. Cao, Taisheng Li, 2015, Journal of the International AIDS Society.

Interleukin-2 therapy in patients with HIV infection.

H. Lane, D. Cooper, A. Phillips, 2009, The New England journal of medicine.

Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.

G. Freeman, J. van Grevenynghe, J. Routy, 2015, The Journal of general virology.

Combined single-cell transcriptional, translational, and genomic profiling reveals HIV-1 reservoir diversity.

D. Kaufmann, J. Routy, M. Dubé, 2021, Cell reports.

Polyfunctional Fc Dependent Activity of Antibodies to Native Trimeric Envelope in HIV Elite Controllers

C. Tremblay, D. Rouleau, J. Routy, 2020, Frontiers in Immunology.

HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2

J. Routy, É. Cohen, T. Pham, 2014, Retrovirology.

Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

D. Douek, B. Hill, J. Routy, 2010, Nature Medicine.

Intrathecal zidovudine for AIDS dementia

F. Viallet, J. Routy, H. Chardon, 1990, The Lancet.

Efficacy and Safety of Switching to Dolutegravir/Lamivudine Fixed-Dose 2-Drug Regimen vs Continuing a Tenofovir Alafenamide–Based 3- or 4-Drug Regimen for Maintenance of Virologic Suppression in Adults Living With Human Immunodeficiency Virus Type 1: Phase 3, Randomized, Noninferiority TANGO Study

J. Routy, S. De Wit, Kimberly Smith, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site.

J. Routy, C. Fletcher, R. Bendayan, 2016, The Journal of antimicrobial chemotherapy.

Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-Glucan

J. Routy, S. Isnard, John Lin, 2021, Frontiers in Immunology.

Dates of HIV infection can be estimated for seroprevalent patients by coalescent analysis of serial next-generation sequencing data

Art F Y Poon, Bluma Brenner, David J H F Knapp, 2011, AIDS.

Quantification of human herpesvirus 8 by real‐time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease

J. Routy, G. Boivin, Yacine Abed, 2002, Journal of medical virology.

Transcription factor FOXO3a controls the persistence of memory CD4+ T cells during HIV infection

G. Boucher, R. Balderas, J. Routy, 2008, Nature Medicine.

Drug efflux transporters and metabolic enzymes in human circulating and testicular T-cell subsets: relevance to HIV pharmacotherapy.

R. Kaul, J. Routy, R. Bendayan, 2020, AIDS.

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

Geneviève Boucher, Mohamed-Rachid Boulassel, Daniel C Douek, 2009, Nature Medicine.

Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection.

C. Tremblay, J. Routy, D. Radzioch, 2015, The Journal of infectious diseases.

Challenges in dendritic cells-based therapeutic vaccination in HIV-1 infection Workshop in dendritic cell-based vaccine clinical trials in HIV-1.

Felipe García, J. Routy, 2011, Vaccine.

Host MicroRNAs-221 and -222 Inhibit HIV-1 Entry in Macrophages by Targeting the CD4 Viral Receptor.

J. Routy, M. Tremblay, C. Power, 2017, Cell reports.

Th17 CD4+ T-Cell as a Preferential Target for HIV Reservoirs

J. Routy, P. Van de Perre, F. Mennechet, 2022, Frontiers in Immunology.

Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA

S. Trottier, C. Tremblay, J. Routy, 2021, Pathogens.

Diurnal Variation of Plasma Extracellular Vesicle Is Disrupted in People Living with HIV

J. Routy, M. Alary, D. Planas, 2021, Pathogens.

Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV

S. Trottier, C. Tremblay, J. Routy, 2021, Pathogens & immunity.

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Kelly A. Fusco, Maria Cristina Lopes, D. Devine, 2021, Nature Medicine.

Upregulated IL-32 Expression And Reduced Gut Short Chain Fatty Acid Caproic Acid in People Living With HIV With Subclinical Atherosclerosis

S. Gange, C. Tremblay, C. Chartrand-Lefebvre, 2021, Frontiers in Immunology.

Progressive emergence of an S153F plus R263K combination of integrase mutations in the proviral DNA of one individual successfully treated with dolutegravir.

Jing Leng, M. Soares, J. Routy, 2020, The Journal of antimicrobial chemotherapy.

Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir

C. Tremblay, B. Brenner, D. Rouleau, 2018, Retrovirology.

Plasticity in T-cell mitochondrial metabolism: A necessary peacekeeper during the troubled times of persistent HIV-1 infection.

J. van Grevenynghe, J. Routy, Xavier Dagenais-Lussier, 2020, Cytokine & growth factor reviews.

Markers of Gut Barrier Function and Microbial Translocation Associate with Lower Gut Microbial Diversity in People with HIV

R. Heaton, R. Ellis, J. Routy, 2021, Viruses.

Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028)

A. Vigano, J. Routy, G. Sebastiani, 2022, Biomedicines.

Current topics in HIV pathogenesis, part 2: Inflammation drives a Warburg-like effect on the metabolism of HIV-infected subjects.

J. van Grevenynghe, J. Routy, M. Jenabian, 2016, Cytokine & growth factor reviews.

Proinflammatory isoforms of IL-32 as novel and robust biomarkers for control failure in HIV-infected slow progressors

S. Trottier, J. Singer, C. Kovacs, 2016, Scientific Reports.

Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy.

J. Routy, R. Sékaly, B. Yassine-Diab, 2010, Clinical immunology.

The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation

J. Routy, A. Marette, Yaokai Chen, 2020, Frontiers in Immunology.

Retrospective study of intravascular large B-cell lymphoma cases diagnosed in Quebec: A retrospective study of 29 case reports: Erratum

T. Petrella, J. Routy, H. Knecht, 2017, Medicine.

Retrospective study of intravascular large B-cell lymphoma cases diagnosed in Quebec

T. Petrella, J. Routy, H. Knecht, 2017, Medicine.

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.

R. Balderas, C. Tremblay, J. van Grevenynghe, 2011, The Journal of clinical investigation.

Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin β7

J. Routy, N. Grandvaux, A. Gosselin, 2011, The Journal of Immunology.

Expression of Integrin Type 1 Infection Regardless of Their Preferential Targets for Productive HIV T Cells Are + CD 4 + Memory CCR 6 and

J. Routy, N. Grandvaux, A. Gosselin, 2011 .

Towards an HIV cure: a global scientific strategy

M. Lederman, J. Mullins, A. Telenti, 2012, Nature Reviews Immunology.

Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors

J. Routy, R. Schinazi, R. Sékaly, 2017, PLoS pathogens.

Concurrent HIV viral blips during two episodes of multicentric Castleman disease in an adult on antiretroviral therapy: Implication for HIV persistence

J. Routy, C. Costiniuk, N. Kronfli, 2021, IDCases.

Correction: Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers

C. Tremblay, J. Routy, D. Radzioch, 2014, PLoS ONE.

Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers

C. Tremblay, J. Routy, D. Radzioch, 2013, PloS one.

HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation.

Z. Grossman, P. Debré, J. Routy, 2004, Immunity.

Cytomegalovirus as an Uninvited Guest in the Response to Vaccines in People Living with HIV

J. Routy, S. Isnard, John Lin, 2021, Viruses.

Treating From the Inside Out: Relevance of Fecal Microbiota Transplantation to Counteract Gut Damage in GVHD and HIV Infection

J. Routy, Yaokai Chen, S. Isnard, 2020, Frontiers in Medicine.

Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection after IL-7 Administration

M. Lederman, V. Natarajan, J. Routy, 2014, PLoS pathogens.

Plasmapheresis in the treatment of an acute pancreatitis due to protease inhibitor‐induced hypertriglyceridemia

J. Routy, B. Gilfix, D. Blank, 2001, Journal of clinical apheresis.

Elevation and persistence of CD8 T-cells in HIV infection: the Achilles heel in the ART era

D. Kaufmann, J. Routy, W. Cao, 2016, Journal of the International AIDS Society.

Regulatory T Cells Negatively Affect IL-2 Production of Effector T Cells through CD39/Adenosine Pathway in HIV Infection

J. Routy, Y. Lévy, J. Sévigny, 2013, PLoS pathogens.

Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach

C. Tremblay, J. Routy, R. Sékaly, 2015, Retrovirology.

Anti-Gag antibodies gag HIV infection and slow disease progression.

C. Tremblay, J. Routy, M. Jenabian, 2018, AIDS.

HIV Gag p24 specific responses secreting IFN-gamma and/or IL-2 in treatment-naïve individuals in acute infection early disease (AIED) are associated with low viral load.

C. Tremblay, D. Rouleau, J. Routy, 2009, Clinical immunology.

Functional T cell subsets contribute differentially to HIV peptide-specific responses within infected individuals: correlation of these functional T cell subsets with markers of disease progression.

C. Tremblay, D. Rouleau, J. Routy, 2007, Clinical immunology.

Recognition of a Defined Region within p24 Gag by CD8+ T Cells during Primary Human Immunodeficiency Virus Type 1 Infection in Individuals Expressing Protective HLA Class I Alleles

E. Rosenberg, M. Altfeld, B. Walker, 2007, Journal of Virology.

Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies

J. Routy, L. Trautmann, R. Sékaly, 2007, Current opinion in HIV and AIDS.

Emergence of Individual HIV-Specific CD8 T Cell Responses during Primary HIV-1 Infection Can Determine Long-Term Disease Outcome

D. Heckerman, E. Rosenberg, H. Jessen, 2014, Journal of Virology.

Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

Anthony D. Kelleher, Hendrik Streeck, Eric S. Rosenberg, 2009, Journal of Virology.

Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

E. Rosenberg, H. Jessen, M. Altfeld, 2009, Journal of Virology.

Decreased levels of circulating IL-21 in HIV-infected AIDS patients: correlation with CD4+ T-cell counts.

C. Tremblay, J. Routy, A. Iannello, 2008, Viral immunology.

4-1BBL Induces TNF Receptor-Associated Factor 1-Dependent Bim Modulation in Human T Cells and Is a Critical Component in the Costimulation-Dependent Rescue of Functionally Impaired HIV-Specific CD8 T Cells1

J. Routy, R. Sékaly, T. Watts, 2007, The Journal of Immunology.

Early lymphocyte recovery following autologous peripheral stem cell transplantation is associated with better survival in younger patients with lymphoproliferative disorders

J. Routy, S. Lachance, P. Laneuville, 2006, Hematology.

Effect of antiretroviral therapy on HIV-1 genetic evolution during acute infection

C. Tremblay, A. Chamberland, D. Rouleau, 2011, International journal of STD & AIDS.

Impaired Th17 polarization of phenotypically naive CD4+ T-cells during chronic HIV-1 infection and potential restoration with early ART

C. Tremblay, J. Routy, S. DaFonseca, 2015, Retrovirology.

Changes in function of HIV-specific T-cell responses with increasing time from infection.

C. Tremblay, D. Rouleau, J. Routy, 2010, Viral immunology.

Assessment of longitudinal changes in HIV-specific effector activity in subjects undergoing untreated primary HIV infection

D. Rouleau, J. Routy, G. Alter, 2004, AIDS.

Human immunodeficiency virus (HIV)-specific effector CD8 T cell activity in patients with primary HIV infection.

D. Rouleau, J. Routy, G. Alter, 2002, The Journal of infectious diseases.

Kinetics of HIV-1 CTL Epitopes Recognized by HLA I Alleles in HIV-Infected Individuals at Times near Primary Infection: The Provir/Latitude45 Study

M. Wainberg, J. Routy, H. Fleury, 2014, PLoS ONE.

Evolution of Antibodies to Native Trimeric Envelope and Their Fc-Dependent Functions in Untreated and Treated Primary HIV Infection

C. Tremblay, D. Rouleau, J. Routy, 2021, Journal of virology.

Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection

B. Haynes, A. McMichael, M. Betts, 2016, PLoS pathogens.

Wide Variation in the Multiplicity of HIV-1 Infection among Injection Drug Users

Hui Li, Chuanxi Sun, Truman Grayson, 2010, Journal of Virology.

Tolerability and Efficacy of PI Versus NNRTI-Based Regimens in Subjects Receiving HAART During Acute or Early HIV Infection

B. Walker, J. Margolick, F. Vaida, 2009, Journal of acquired immune deficiency syndromes.

Persistence and Fitness of Multidrug-Resistant Human Immunodeficiency Virus Type 1 Acquired in Primary Infection

Bluma G. Brenner, M. Wainberg, B. Brenner, 2002, Journal of Virology.

Very early antiretroviral therapy permits CD8 T cells to keep HIV reservoirs at bay.

J. Routy, V. Mehraj, 2017, Annals of translational medicine.

Relative contribution of HIV-specific functional lymphocyte subsets restricted by protective and non-protective HLA alleles.

C. Tremblay, D. Rouleau, J. Routy, 2011, Viral immunology.

Receptor-Ligand Requirements for Increased NK Cell Polyfunctional Potential in Slow Progressors Infected with HIV-1 Coexpressing KIR3DL1*h/*y and HLA-B*57

C. Brander, C. Kovacs, S. Migueles, 2011, Journal of Virology.

High rates of forward transmission events after acute/early HIV-1 infection.

Michel Roger, M. Wainberg, C. Tremblay, 2007, The Journal of infectious diseases.

Corrigendum: Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

R. Balderas, E. Delwart, J. Routy, 2006, Nature Medicine.

Short communication: antibody responses to human immunodeficiency virus envelope from infections with multiple subtypes utilize the 1F7-idiotypic repertoire.

M. Wainberg, C. Tremblay, R. Center, 2013, AIDS research and human retroviruses.

Persistence of multidrug-resistant HIV-1 in primary infection leading to superinfection

M. Wainberg, B. Brenner, D. Moisi, 2004, AIDS.

Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use

M A Wainberg, M. Wainberg, B. Brenner, 2000, AIDS.

The effects of antiretroviral therapy initiation time on HIV reservoir size in Chinese chronically HIV infected patients: a prospective, multi-site cohort study

J. Routy, Hongzhou Lu, W. Lv, 2019, BMC Infectious Diseases.

Highlights from the 22nd International AIDS Conference (AIDS 2018), 22–27 July 2018, Amsterdam, the Netherlands

J. Routy, S. Collins, S. Moreno, 2018, Journal of virus eradication.

A higher CD4/CD8 ratio correlates with an ultralow cell-associated HIV-1 DNA level in chronically infected patients on antiretroviral therapy: a case control study

J. Routy, Taisheng Li, J. Xie, 2017, BMC Infectious Diseases.

The Effect of Therapeutic HIV Vaccination With ALVAC-HIV With or Without Remune on the Size of the Viral Reservoir (A CTN 173 Substudy)

C. Tremblay, J. Routy, J. Angel, 2015, Journal of acquired immune deficiency syndromes.

A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune

J. Singer, C. Kovacs, C. Tremblay, 2011, AIDS.

Natural Killer Cells from HIV Infected Slow Progressors Who Carry the Protective HLA-B*27 Allele and Inhibitory KIR3DL1 Receptors Have Elevated Poly-Functional Potential Compared to Bw6 Homozygotes

C. Kovacs, S. Migueles, M. Connors, 2011 .

CD4 mimetics sensitize HIV-1-infected cells to ADCC

J. Sodroski, B. Haynes, D. Kaufmann, 2015, Proceedings of the National Academy of Sciences.

HIV-1 Viremia Prevents the Establishment of Interleukin 2–producing HIV-specific Memory CD4+ T Cells Endowed with Proliferative Capacity

Z. Grossman, J. Routy, R. Sékaly, 2003, The Journal of experimental medicine.

CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

R. Balderas, C. Tremblay, J. Routy, 2012, PLoS pathogens.

Characterization of humoral and cell-mediated immune responses directed against hepatitis C virus F protein in subjects co-infected with hepatitis C virus and HIV-1

J. Routy, N. Lapointe, J. Bruneau, 2005, AIDS.

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals

D. Hazuda, S. Lewin, F. Hecht, 2019, Nature Communications.

Kynurenine Reduces Memory CD 4 T-cell Survival by 1 Interfering with IL-2 Signaling early During HIV-1 Infection

C. Tremblay, J. van Grevenynghe, J. Routy, 2016 .

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

D. Kaufmann, J. Routy, M. Massanella, 2019, PLoS pathogens.

Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir

B. Brenner, J. Routy, M. Robbins, 2018, Retrovirology.

Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection.

M. Altfeld, J. Margolick, R. Schooley, 2011, The Journal of infectious diseases.

Tripterygium wilfordii Hook F extract in cART-treated HIV patients with poor immune response: a pilot study to assess its immunomodulatory effects and safety

J. Xie, Fu-Sheng Wang, J. Routy, 2015, HIV clinical trials.

Serum cryptococcal antigen titre as a diagnostic tool and a predictor of mortality in HIV‐infected patients with cryptococcal meningitis

J. Routy, V. Mehraj, J. Chen, 2018, HIV medicine.

Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals

J. Routy, J. Bruneau, C. Tsoukas, 2008, AIDS.

A prospective, non-randomised phase 1-2 trial of VACOP-B with filgrastim support for HIV-related non-Hodgkin's lymphoma.

F. Shepherd, J. Routy, K. Arts, 2005, Biotechnology annual review.

Functionally Impaired HIV-Specific CD8 T in the Costimulation-Dependent Rescue of Human T Cells and Is a Critical Component Factor 1-Dependent Bim Modulation in 4-1BBL Induces TNF Receptor-Associated

J. Routy, R. Sékaly, T. Watts, 2007 .

Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis.

J. Routy, Y. Xu, V. Yotova, 2021, The Journal of clinical investigation.

HIV-1 is rarely detected in blood and colon myeloid cells during viral-suppressive antiretroviral therapy.

J. Routy, É. Cohen, D. Planas, 2019, AIDS.

CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features.

C. Tremblay, J. Routy, J. Goulet, 2018, Blood advances.

Understanding the Risks and Benefits of a Patient Portal Configured for HIV Care: Patient and Healthcare Professional Perspectives

J. Routy, K. Lacombe, N. Sheehan, 2022, Journal of personalized medicine.

Association Between Gut Microbiota and CD4 Recovery in HIV-1 Infected Patients

J. Xie, W. Lu, B. Zhu, 2018, Front. Microbiol..

The Canadian HIV and aging cohort study - determinants of increased risk of cardio-vascular diseases in HIV-infected individuals: rationale and study protocol

S. Trottier, M. Abrahamowicz, C. Kovacs, 2017, BMC Infectious Diseases.

Autologous HIV-1 Clade-B Nef Peptides Elicit Increased Frequency, Breadth and Function of CD8+ T-Cells Compared to Consensus Peptides

J. Routy, R. Sékaly, M. Doroudchi, 2012, PloS one.

HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation

C. Tremblay, J. Routy, D. Amre, 2018, PloS one.

Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection

Todd M. Allen, E. Rosenberg, H. Jessen, 2013, Retrovirology.

HIV infection affects blood myeloid dendritic cells after successful therapy and despite nonprogressing clinical disease.

C. Tremblay, J. Routy, J. Fontaine, 2009, The Journal of infectious diseases.

Kaposi sarcoma in ART-treated people living with HIV: A wake-up call for research on HHV-8.

J. Routy, A. Calmy, S. Isnard, 2021, AIDS.

Identifying the early post-HIV antibody seroconversion period.

J. Margolick, S. Little, R. Wellman, 2011, The Journal of infectious diseases.

Immunophenotypic patterns of CD8+ T cell subsets expressing CD8αα and IL-7Rα in viremic, aviremic and slow progressor HIV-1-infected subjects

J. Routy, F. Mercier, N. Gilmore, 2007 .

NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts

J. Routy, J. Bruneau, B. Lebouché, 2016, PloS one.

New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy

J. Routy, J. Goulet, S. Deeks, 2016, Retrovirology.

Antibody-Dependent Cellular Cytotoxicity-Competent Antibodies against HIV-1-Infected Cells in Plasma from HIV-Infected Subjects

C. Tremblay, J. Routy, M. Pazgier, 2019, mBio.

Quantifying Anti-HIV Envelope-Specific Antibodies in Plasma from HIV Infected Individuals

C. Tremblay, D. Rouleau, J. Routy, 2019, Viruses.

IL‐21 enhances NK cell functions and survival in healthy and HIV‐infected patients with minimal stimulation of viral replication

C. Tremblay, J. Routy, A. Iannello, 2010, Journal of leukocyte biology.

Dynamics and Consequences of IL-21 Production in HIV-Infected Individuals: A Longitudinal and Cross-Sectional Study

C. Tremblay, J. Routy, A. Iannello, 2009, The Journal of Immunology.

Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo

B. Liao, Corbin D. Jones, J. Lifson, 2020, Nature.

Responses: Comparison with B7.1 and of Human Antiviral Memory CD8 T Cell Evaluation of OX40 Ligand as a Costimulator

M. Ostrowski, J. Routy, R. Sékaly, 2013 .

Enhancement of HIV-Specific CD8 T Cell Responses by Dual Costimulation with CD80 and CD137L1

M. Ostrowski, C. Kovacs, K. MacDonald, 2005, The Journal of Immunology.

Evaluation of OX40 Ligand as a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL1

M. Ostrowski, J. Routy, R. Sékaly, 2005, The Journal of Immunology.

Evaluation of OX 40 Ligand as a Costimulator of Human Antiviral Memory CD 8 T Cell Responses : Comparison with B 7 . 1 and 4-1 BBL 1

M. Ostrowski, J. Routy, R. Sékaly, 2005 .

L Responses by Dual Costimulation with CD 80 Enhancement of HIV-Specific CD 8 T Cell

M. Ostrowski, C. Kovacs, K. MacDonald, 2005 .

Phenotypic characterization of single CD4+ T cells harboring genetically intact and inducible HIV genomes

J. Routy, B. Murrell, M. Massanella, 2023, Nature Communications.

Highlights from the 8th International Workshop on HIV Persistence during Therapy, 12–15 December 2017, Miami, FL, USA

J. Routy, D. Margolis, M. Stevenson, 2018, Journal of virus eradication.

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

J. Routy, R. Sékaly, F. Diaz-Griffero, 2009, The Journal of Immunology.

Latency-Reversing Agents Induce Differential Responses in Distinct Memory CD4 T Cell Subsets in Individuals on Antiretroviral Therapy.

J. Routy, R. Fromentin, N. Chomont, 2019, Cell reports.

HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy

J. Routy, É. Cohen, D. Planas, 2016, AIDS.

Metformin effect on gut microbiota: insights for HIV-related inflammation

J. Routy, A. Marette, Yaokai Chen, 2020, AIDS Research and Therapy.

OP 3.3 – 00030 Inducible replication-competent HIV proviruses persist in memory CD4+ T cells expressing high levels of the integrin VLA-4 (α4β1)

J. Routy, M. Massanella, B. Routy, 2022, Journal of virus eradication.

IL-10 driven memory T cell survival and Tfh differentiation promote HIV persistence

D. Hazuda, N. Krogan, R. Balderas, 2021, bioRxiv.

HIV-1 selectively targets gut-homing CCR6+CD4+ T cells via mTOR-dependent mechanisms.

T. Hope, J. Routy, A. Fassati, 2017, JCI insight.

Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation

J. Routy, A. Fassati, R. Ketteler, 2017, PLoS pathogens.

Design and Implementation of a Randomized Crossover Study of Valproic Acid and Antiretroviral Therapy to Reduce the HIV Reservoir

S. Trottier, J. Singer, C. Tremblay, 2012, HIV clinical trials.

Valproic acid: a potential role in treating latent HIV infection

J. Routy, 2005, The Lancet.

Persistence of high levels of blood soluble human leukocyte antigen-G is associated with rapid progression of HIV infection

C. Tremblay, J. Routy, J. Fontaine, 2009, AIDS.

Latest developments in tryptophan metabolism: Understanding its role in B cell immunity.

J. van Grevenynghe, J. Routy, Xavier Dagenais-Lussier, 2021, Cytokine & growth factor reviews.

Combination antiretroviral therapy and indoleamine 2,3-dioxygenase in HIV infections: challenges and new opportunities.

C. Tremblay, J. Routy, M. Jenabian, 2016, AIDS.

Concurrent development of HIV-negative Kaposi’s sarcoma and mycosis fungoides in an elderly Inuit from Canada

J. Routy, John Lin, Louis-André Julien, 2021, BMJ Case Reports.

A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses.

C. Tremblay, J. Routy, R. Sékaly, 2007, Journal of immunological methods.

Longitudinal Assessment of Changes in HIV-Specific Effector Activity in HIV-Infected Patients Starting Highly Active Antiretroviral Therapy in Primary Infection 1

D. Rouleau, B. Conway, J. Routy, 2003, The Journal of Immunology.

Antiretroviral Therapy in Primary Infection HIV-Infected Patients Starting Highly Active HIV-Specific Effector Activity in Longitudinal Assessment of Changes in Sékaly

D. Rouleau, B. Conway, J. Routy, 2003 .

Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults

J. Routy, R. Bendayan, R. Fromentin, 2016, AIDS.

Characterization of myeloid cell populations in human testes collected after sex reassignment surgery.

F. Brimo, J. Routy, M. Jenabian, 2018, Journal of reproductive immunology.

Alcohol Use and Abuse Conspires With HIV Infection to Aggravate Intestinal Dysbiosis and Increase Microbial Translocation in People Living With HIV: A Review

J. Routy, Yaokai Chen, S. Isnard, 2021, Frontiers in Immunology.

Improvement of HIV-specific immunity in HIV-infected twins treated with highly active antiretroviral therapy, interleukin 2, and syngeneic adoptively transferred cells.

C. Kovacs, J. Routy, S. Walmsley, 2001, AIDS research and human retroviruses.

Allogeneic Hematopoietic Stem Cell Transplant Infusion During Venovenous Extracorporeal Membrane Oxygenation Support

J. Routy, G. Samoukovic, G. Popradi, 2021, Critical care explorations.

Concurrent BK polyomavirus, adenovirus and cytomegalovirus infections in a patient treated for chronic lymphocytic leukaemia

J. Routy, John Lin, M. Kwok, 2021, BMJ Case Reports.

Multiplexed technologies for sexually transmitted infections: global evidence on patient-centered and clinical health outcomes

J. Routy, S. Nair, C. Yansouni, 2021, BMJ Global Health.

Multiplexed rapid technologies for sexually transmitted infections: a systematic review.

J. Routy, C. Yansouni, N. Pai, 2021, The Lancet. Microbe.

CD4 T cell nadir independently predicts the magnitude of the HIV reservoir after prolonged suppressive antiretroviral therapy.

J. Routy, R. Sékaly, N. Pai, 2012, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Reversing Gut Damage in HIV Infection: Using Non-Human Primate Models to Instruct Clinical Research

J. Routy, R. Cheynier, P. Ghali, 2016, EBioMedicine.

Antiretroviral Therapy in Primary HIV-1 Infection: Influences on Immune Activation and Gut Mucosal Barrier Dysfunction.

J. Routy, W. Cao, Taisheng Li, 2015, AIDS reviews.

HIV immunotherapy comes of age: implications for prevention, treatment and cure

J. Routy, W. Cao, V. Mehraj, 2016, Expert review of clinical immunology.

Slow disease progression and robust therapy-mediated CD4+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection.

J. Routy, R. Cheynier, R. Sékaly, 2007, Blood.

Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

J. Routy, K. Karwacz, A. Fassati, 2021, Proceedings of the National Academy of Sciences.

Switching to DTG/3TC fixed-dose combination (FDC) Is non-inferior to continuing a TAF-based regimen in maintaining virologic suppression through 48 weeks (TANGO Study)

J. Routy, J. V. Wyk, M. Aboud, 2020 .

Plasma Indoleamine 2,3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy

J. Routy, Hongzhou Lu, Yinzhong Shen, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Short communication: human immunodeficiency virus rebound in blood and seminal plasma following discontinuation of antiretroviral therapy.

J. Singer, C. Kovacs, J. Routy, 2012, AIDS research and human retroviruses.

Prevalence and predictors of airflow obstruction in an HIV tertiary care clinic in Montreal, Canada: a cross‐sectional study

J. Bourbeau, J. Routy, J. Bourbeau, 2019, HIV medicine.

Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028—study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation

J. Singer, J. Routy, M. Brouillette, 2019, BMJ Open.

Virologic and Immunologic Response to a Boosted Double-Protease Inhibitor-Based Therapy in Highly Pretreated HIV-1-Infected Patients

J. Routy, R. Lalonde, Graham H R Smith, 2005, HIV clinical trials.

Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression

C. Tremblay, J. Routy, P. Provost, 2015, Journal of acquired immune deficiency syndromes.

The Frequency and Function of NKG2C+CD57+ Adaptive NK Cells in Cytomagalovirus Co-Infected People Living with HIV Decline with Duration of Antiretroviral Therapy

C. Tremblay, J. Routy, J. Bruneau, 2023, Viruses.

The option of treatment and outcomes for patients with AIDS-related diffuse large B-cell lymphoma from a resource-limited setting in China

J. Routy, Hengning Ke, John Lin, 2019, Leukemia & lymphoma.

COVID-19 vaccine immunogenicity in people with HIV

A. Burchell, M. Ostrowski, C. Kovacs, 2022, AIDS.

GDF-15 as a Weight Watcher for Diabetic and Non-Diabetic People Treated With Metformin

J. Routy, Yaokai Chen, S. Isnard, 2020, Frontiers in Endocrinology.

CTL Clonotypes with Higher TCR Affinity Have Better Ability to Reduce the HIV Latent Reservoir

V. Appay, J. Routy, L. Trautmann, 2020, The Journal of Immunology.

The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication

J. Routy, A. Gatignol, A. Mouland, 2013, Retrovirology.

(5R)-5-hydroxytriptolide for HIV immunological non-responders receiving ART: a randomized, double-blinded, placebo-controlled phase II study

Y. Li, J. Routy, B. Zhu, 2023, The Lancet regional health. Western Pacific.

CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort study

J. Singer, A. Burchell, M. Ostrowski, 2021, BMJ Open.

Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection

E. Kremmer, M. Ostrowski, C. Kovacs, 2012, The Journal of experimental medicine.

Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier

J. Routy, R. Bendayan, M. Jenabian, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Immunologic thrombocytopenia followed by thrombotic thrombocytopenic purpura in two HIV1 patients

G. Sauvageau, J. Routy, R. Beaulieu, 1991, American journal of hematology.

Near full-length genomic analysis of a novel subtype A1/C recombinant HIV type 1 isolate from Canada.

M. Wainberg, M. Ntemgwa, B. Brenner, 2008, AIDS research and human retroviruses.

Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

J. Routy, D. Margolis, D. Asmuth, 2016, Journal of acquired immune deficiency syndromes.

Evaluation of a project to engage patients in the development of a patient‐reported measure for HIV care (the I‐Score Study)

J. Routy, B. Lebouché, K. Engler, 2018, Health expectations : an international journal of public participation in health care and health policy.

Coping With Stress: The Mitokine GDF-15 as a Biomarker of COVID-19 Severity

J. Routy, S. Isnard, John Lin, 2022, Frontiers in Immunology.

RALDH Activity Induced by Bacterial/Fungal Pathogens in CD16+ Monocyte-Derived Dendritic Cells Boosts HIV Infection and Outgrowth in CD4+ T Cells

J. Routy, J. Estaquier, É. Cohen, 2021, The Journal of Immunology.

The anti-inflammatory IL-37/SIGIRR axis is functionally compromised in HIV infection.

C. Tremblay, J. Routy, D. Amre, 2019, AIDS.

Differential synthesis and release of IL‐18 and IL‐18 Binding Protein from human platelets and their implications for HIV infection

C. Tremblay, J. Routy, D. Amre, 2017, Cytokine.

Comparison of clinical features of acute HIV-1 infection in patients infected sexually or through injection drug use. The Investigators of the Québec Primary HIV Infection Study.

P. Vanhems, D. Rouleau, B. Conway, 2000, Journal of acquired immune deficiency syndromes.

Predictive value of interleukin-7 levels for virological response to treatment in HIV-1-infected children.

J. Routy, N. Lapointe, H. Soudeyns, 2007, Viral immunology.

Antiretroviral Drug Transporters and Metabolic Enzymes in Circulating Monocytes and Monocyte-Derived Macrophages of ART-Treated People Living With HIV and HIV-Uninfected Individuals

J. Routy, C. Fletcher, R. Bendayan, 2021, Journal of acquired immune deficiency syndromes.

Genetic Basis of Hypersusceptibility to Protease Inhibitors and Low Replicative Capacity of Human Immunodeficiency Virus Type 1 Strains in Primary Infection

J. Corbeil, J. Margolick, D. Richman, 2004, Journal of Virology.

Impaired Th17 polarization of phenotypically naive CD4+ T-cells during chronic HIV-1 infection and potential restoration with early ART

C. Tremblay, J. Routy, S. DaFonseca, 2015, Retrovirology.

Imatinib for highly chemoresistant Kaposi sarcoma in a patient with long-term HIV control: a case report and literature review.

J. Routy, B. Routy, W. Cao, 2015, Current oncology.

More than a Gender Issue: Testis as a Distinctive HIV Reservoir and Its Implication for Viral Eradication.

J. Routy, S. Isnard, John Lin, 2022, Methods in molecular biology.

Combination of Tripterygium Wilfordii Hook F With Antiretroviral Therapy Delayed Viral Rebound in A Patient of Acute HIV-1 Infection

J. Routy, Yizhi Cui, W. Cao, 2021, Infectious Diseases & Immunity.

The grace of aging with ART: Ex vivo dendritic cell-based immunotherapy restores HIV-specific functional CD8+ T-cells

J. Routy, V. Mehraj, Jamil Ahmed, 2022, EBioMedicine.

Anti-CMV IgG is linked to CD4 T-cell count decay in HIV elite controllers.

C. Tremblay, J. Routy, S. Isnard, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Potential role of IL-18 in the immunopathogenesis of AIDS, HIV-associated lipodystrophy and related clinical conditions.

C. Tremblay, J. Routy, A. Iannello, 2010, Current HIV research.

Factors associated with a decrease in the prevalence of drug resistance in newly HIV-1 infected individuals in Montreal

M. Wainberg, C. Tremblay, B. Brenner, 2004, AIDS.

Loss of CD96 Expression as a Marker of HIV-Specific CD8+ T-Cell Differentiation and Dysfunction

D. Kaufmann, C. Tremblay, C. Chartrand-Lefebvre, 2021, Frontiers in Immunology.

Purging the HIV-1 reservoir through the disruption of the PD-1 pathway

J. Routy, R. Sékaly, S. DaFonseca, 2010, Journal of the International AIDS Society.

The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies

B. Walker, R. Schooley, S. Little, 2018, The Journal of infectious diseases.

Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection

S. Migueles, M. Connors, R. Koup, 2015, The Journal of Immunology.

Primary lung cancer diagnoses in people living with HIV in a large clinical centre in Montreal, Canada over 3 decades

J. Routy, C. Costiniuk, N. Ezer, 2020, AIDS care.

Potential contribution of gut microbiota and systemic inflammation on HIV vaccine effectiveness and vaccine design

J. Routy, V. Mehraj, 2017, AIDS Research and Therapy.

Pharmacological Inhibition of PPARy Boosts HIV Reactivation and Th17 Effector Functions, While Preventing Progeny Virion Release and de novo Infection

J. Routy, J. Goulet, J. Richard, 2020, Pathogens & immunity.

Relevance of biomarkers indicating gut damage and microbial translocation in people living with HIV

J. Routy, H. Cui, Yaokai Chen, 2023, Frontiers in Immunology.

[Fatal complication during treatment with elliptinium acetate].

J. Routy, B. Garrigues, A. Blanc, 1985, Presse medicale.

Accident mortel au cours d'un traitement par l'acétate d'elliptinium

J. Routy, B. Garrigues, Blanc Ap, 1985 .

Performance of Bio-Rad and Limiting Antigen Avidity Assays in Detecting Recent HIV Infections Using the Quebec Primary HIV-1 Infection Cohort

C. Tremblay, J. Routy, D. Hamel, 2016, PLoS ONE.

Primary lymphoma of the brain associated with AIDS

J. Routy, B. Alliez, M. Payan, 2004, Acta Neuropathologica.

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy

J. Routy, H. Fleury, A. Gosselin, 2021, Gut Pathogens.

Epigenetic impairment and blunted transcriptional response to Mycobacterium tuberculosis of alveolar macrophages from persons living with HIV

J. Routy, V. Yotova, R. Olivenstein, 2021, medRxiv.

Highlights of the 9th edition of the Conference on HIV Persistence During Therapy, 10–13 December 2019, Miami, USA

J. Routy, D. Margolis, M. Stevenson, 2020, Journal of virus eradication.

Antibody-Dependent Cellular Cytotoxicity Activity of Effector Cells from HIV-Infected Elite and Viral Controllers.

M. Wainberg, C. Kovacs, C. Tremblay, 2016, AIDS research and human retroviruses.

Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach

C. Tremblay, J. Routy, R. Sékaly, 2015, Retrovirology.

The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication

J. Routy, A. Gatignol, A. Mouland, 2013, Retrovirology.

Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy

D. Kaufmann, J. Routy, J. Richard, 2020, EBioMedicine.

Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique

D. Kaufmann, J. Routy, Nirmin Alsahafi, 2017, Nature Protocols.

[HIV-1 primo-infection and cytomegalovirus reactivation in 2 intravenous drug users. Prognostic significance].

J. Routy, H. Chardon, O. Bellon, 1990, Annales de medecine interne.

HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy

J. Routy, J. Joy, A. Poon, 2019, Journal of Virology.

Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gamma as an intrinsic negative regulator of viral replication

C. Tremblay, J. Routy, J. Goulet, 2013, Retrovirology.

recovery are associated with efficient thymopoiesis during HIV-1 infection Slow disease progression and robust therapy-mediated CD4+ T-cell

J. Routy, R. Cheynier, R. Sékaly, 2013 .

Differential Impact of IL-32 Isoforms on the Functions of Coronary Artery Endothelial Cells: A Potential Link with Arterial Stiffness and Atherosclerosis

C. Tremblay, C. Chartrand-Lefebvre, J. Routy, 2023, Viruses.

Interleukin-1β Triggers p53-Mediated Downmodulation of CCR5 and HIV-1 Entry in Macrophages through MicroRNAs 103 and 107

J. Routy, Mélanie Laporte, É. Cohen, 2020, mBio.

Convalescent Plasma: The Relay Baton in the Race for Coronavirus Disease 2019 Treatment

J. Routy, Yaokai Chen, S. Isnard, 2020, Frontiers in Immunology.

The Colocalization Potential of HIV-Specific CD8+ and CD4+ T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid

C. Tremblay, J. Routy, N. Chomont, 2012, PloS one.

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in patients receiving antiretroviral therapy: a study from Provir/Latitude45 project

M. Soares, J. Routy, H. Fleury, 2020, bioRxiv.

French HIV Experts on Early Antiretroviral Treatment for Prevention

J. Routy, W. Rozenbaum, B. Spire, 2014, Journal of the International Association of Providers of AIDS Care.

SEIZURE AFTER ZIDOVUDINE OVERDOSE

F. Viallet, J. Routy, A. Blanc, 1989, The Lancet.

Immunophenotypic patterns of CD8+ T cell subsets expressing CD8alphaalpha and IL-7Ralpha in viremic, aviremic and slow progressor HIV-1-infected subjects.

J. Routy, F. Mercier, N. Gilmore, 2007, Clinical Immunology.

The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy – CTN PT006: study protocol for a randomized controlled trial

J. Singer, J. Routy, M. Brouillette, 2014, Trials.

The CD4 cell count 3 months after acute retroviral syndrome is associated with the presence of AIDS in the source individual.

P. Vanhems, L. Perrin, B. Hirschel, 2002, AIDS (London).

A Randomized Controlled Trial of Palifermin (Recombinant Human Keratinocyte Growth Factor) for the Treatment of Inadequate CD4+ T-Lymphocyte Recovery in Patients with HIV-1 Infection on Antiretroviral Therapy

D. Haas, J. Routy, R. Sékaly, 2014, Journal of acquired immune deficiency syndromes.

The TLR7/IRF-5 axis sensitizes memory CD4+ T cells to Fas-mediated apoptosis during HIV-1 infection

J. van Grevenynghe, J. Routy, S. Isnard, 2023, JCI insight.

The SMAC Mimetic AZD5582 is a Potent HIV Latency Reversing Agent

Corbin D. Jones, J. Routy, D. Margolis, 2018, bioRxiv.

Acceptability of a Patient Portal (Opal) in HIV Clinical Care: A Feasibility Study

T. Schuster, J. Routy, J. Kildea, 2021, Journal of personalized medicine.

Treating since the beginning?

J. Routy, 2012, Retrovirology.

Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance

Susanne May, Christopher H Woelk, J. Margolick, 2008, AIDS.

Combination therapy for HIV: towards long term control of disease progression.

B. Conway, J. Routy, R. Sekaly, 1998, Expert opinion on investigational drugs.

Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial

J. Routy, G. Sebastiani, N. Chomont, 2023, Cells.

Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032)

J. Routy, A. Marette, S. Isnard, 2022, BMJ Open.

The Duration of Exposure to HIV Modulates the Breadth and the Magnitude of HIV-Specific Memory CD4+ T Cells

Z. Grossman, J. Routy, L. Trautmann, 2007, The Journal of Immunology.

Effect of early initiation of highly active antiretroviral therapy on CD4 cell count and HIV‐RNA viral load trends within 24 months of the onset of acute retroviral syndrome *

N. Voirin, P. Vanhems, J. Routy, 2008, HIV medicine.

Proceedings of the Frontiers of Retrovirology Conference 2016

Sebastian A. Wagner, R. König, D. Elleder, 2016, Retrovirology.

CRF01_AE subtype is associated with X4 tropism and fast HIV progression in Chinese patients infected through sexual transmission

J. Routy, W. Lv, L. Gu, 2014, AIDS.

Title Dendritic cell immunotherapy for HIV-1 infection using autologous HIV-1 RNA : A randomized , double-blind , placebo-controlled clinical trial Permalink

J. Routy, D. Margolis, D. Asmuth, 2022 .

Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study

C. Tremblay, J. Routy, Réjean Thomas, 2023, BMJ Open.

Circulating Levels of IL-7 but not IL-15, IGF-1, and TGF-β Are Elevated During Primary HIV-1 Infection

C. Tremblay, D. Rouleau, J. Routy, 2004, HIV clinical trials.

Interleukin‐7 levels may predict virological response in advanced HIV‐1‐infected patients receiving lopinavir/ritonavir‐based therapy

J. Routy, R. Lalonde, M. Klein, 2003, HIV medicine.

Optimizing the efficiency of therapeutic HIV vaccine trials: A case for CTN 173

J. Singer, C. Tremblay, J. Routy, 2012 .

Impact of Autologous Dendritic Cell Immunotherapy (Arcelis™) on B Cell Subsets in HIV-1-Infected Subjects Receiving Antiretroviral Therapy

J. Routy, R. Sékaly, B. Yassine-Diab, 2008 .

HIV-Specific Memory CD4+ T Cells the Breadth and the Magnitude of The Duration of Exposure to HIV Modulates

Z. Grossman, J. Routy, R. Sékaly, 2013 .

HIV-Specific Memory CD 4 the Breadth and the Magnitude of The Duration of Exposure to HIV Modulates

Z. Grossman, J. Routy, L. Trautmann, 2006 .

Harnessing Autophagy to Overcome Antigen-Specific T-Cell Dysfunction: Implication for People Living with HIV-1

J. van Grevenynghe, J. Routy, S. Isnard, 2023, International journal of molecular sciences.

Role of fatty liver in the epidemic of advanced chronic liver disease among people with HIV: protocol for the Canadian LIVEHIV multicentre prospective cohort

J. Routy, G. Sebastiani, S. Walmsley, 2023, BMJ open.

Beyond the Absence of CD4 T-Cell Count: A Novel Genetic CD4 T-Cell Deficiency Disorder With a Contingency Plan

J. Routy, S. Isnard, 2021, The Journal of infectious diseases.

Translocation of bacterial LPS is associated with self-reported cognitive abilities in men living with HIV receiving antiretroviral therapy

L. Fellows, N. Mayo, M. Goldberg, 2023, AIDS Research and Therapy.

Kynurenine Reduces Memory CD4 T-Cell Survival by Interfering with Interleukin-2 Signaling Early during HIV-1 Infection

C. Tremblay, J. van Grevenynghe, J. Routy, 2016, Journal of Virology.

Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV‐1 reservoirs: results from a multicentre randomized clinical study

S. Trottier, J. Singer, C. Tremblay, 2012, HIV medicine.

Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report

J. Routy, J. Karamchandani, C. Costiniuk, 2018, BMC Infectious Diseases.

Multiple remissions of extracavitary primary effusion lymphoma treated with a single cycle of liposomal doxorubicin in a patient infected with HIV.

J. Routy, R. Michel, B. Routy, 2018, Current oncology.

[Atrioventricular blocks in relapsing polychondritis. Cases of complete block explored by endocavitary tract].

J. Routy, P. Quittet, J. Medvedowsky, 1988, Presse medicale.

Comparative analysis of the T cell receptor V beta repertoire in various lymphoid tissues from HIV-infected patients: evidence for an HIV-associated superantigen.

J. Routy, H. Soudeyns, R. Sekaly, 1994, Leukemia.

Multiple Cycles of Rituximab Therapy in Chronic Refractory Immune Thrombocytopenia: A Case Report With a 10-Year Follow-up

J. Routy, B. Routy, M. Warner, 2013, American journal of therapeutics.

Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART.

J. Routy, R. Fromentin, N. Chomont, 2023, Cell reports.

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

J. Routy, R. Sékaly, C. Riou, 2013, The Journal of Immunology.

Plasma Level of Soluble ST2 in Chronically Infected HIV-1 Patients with Suppressed Viremia

J. Routy, J. Reynes, P. Corbeau, 2017, The open AIDS journal.

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

J. Routy, R. Sékaly, F. Diaz-Griffero, 2009, The Journal of Immunology.

New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy

J. Routy, J. Goulet, S. Deeks, 2016, Retrovirology.

Overt IL-32 isoform expression at intestinal level during HIV-1 infection is negatively regulated by IL-17A

C. Tremblay, J. Routy, A. Landay, 2021, AIDS.

Accounting for dropout reason in longitudinal studies with nonignorable dropout

Camille M. Moore, B. Conway, J. Routy, 2017, Statistical methods in medical research.

Wide Variation in the Multiplicity of HIV-1 Infection among Injection Drug Users

G. Learn, B. Haynes, C. Morgan, 2010, Journal of Virology.

An army marches on its stomach: immunometabolic dysregulation in persons with HIV.

J. Routy, S. Isnard, 2023, AIDS.

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

J. Routy, R. Sékaly, C. Riou, 2013, The Journal of Immunology.

This information is current as Cell Subsets in HIV-1 Infection Abnormal Distribution of Naive / Memory T Programmed Death-1 Is a Marker for Routy

J. Routy, R. Sékaly, C. Riou, 2013 .

Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy.

J. Routy, R. Sékaly, B. Yassine-Diab, 2010, Clinical immunology.

A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection

J. Routy, J. Bruneau, C. Tsoukas, 2008, AIDS.

HIV-1 causes an imbalance in the production of interleukin-18 and its natural antagonist in HIV-infected individuals: implications for enhanced viral replication.

C. Tremblay, J. Routy, A. Iannello, 2010, Journal of Infectious Diseases.

Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells.

D. Kaufmann, J. Routy, M. Dubé, 2023, Cell host & microbe.

Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation

R. Koup, D. Douek, D. Ambrozak, 2012, The Journal of Immunology.

IL‐21 enhances NK cell functions and survival in healthy and HIV‐infected patients with minimal stimulation of viral replication

C. Tremblay, J. Routy, A. Iannello, 2010, Journal of leukocyte biology.

Variability in the PR and RT Genes of HIV-1 Isolated from Recently Infected Subjects

Dan Turner, Bluma Brenner, M. Wainberg, 2004, Antiviral chemistry & chemotherapy.

Retinoic Acid Boosts HIV-1 Replication in Macrophages via CCR5/SAMHD1-Dependent and mTOR-Modulated Mechanisms

J. Routy, J. Goulet, Laurence Raymond Marchand, 2023, bioRxiv.

Persistence of high levels of blood soluble human leukocyte antigen-G is associated with rapid progression of HIV infection

C. Tremblay, J. Routy, J. Fontaine, 2009, AIDS.

Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age.

P. Vanhems, L. Perrin, B. Hirschel, 2002, Journal of acquired immune deficiency syndromes.

Interleukin-2 Therapy in Patients with HIV Infection

J. Routy, D. Wentworth, G. Tambussi, 2009 .

Soluble CD40‐ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection

J. Routy, I. Kema, R. Lapointe, 2014, Clinical and experimental immunology.

Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gamma as an intrinsic negative regulator of viral replication

C. Tremblay, J. Routy, J. Goulet, 2013, Retrovirology.

Preventative behaviours and COVID-19 infection in a Canadian cohort of people living with HIV

A. Burchell, J. Routy, A. Anis, 2023, AIDS Research and Therapy.

Effects of statins beyond lipid-lowering agents in ART-treated HIV infection

J. Routy, V. Mehraj, Jun Chen, 2024, Frontiers in immunology.

Self-tests for COVID-19: What is the evidence? A living systematic review and meta-analysis (2020–2023)

J. Routy, K. Dheda, P. O’Byrne, 2023, medRxiv.

Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms.

C. Van Lint, J. Routy, J. Goulet, 2024, Cell Reports.

Ongoing impact of the social determinants of health during the second and third waves of the COVID-19 pandemic in People Living with HIV receiving care in a Montreal-based Tertiary Care Centre.

J. Routy, C. Costiniuk, C. Frenette, 2022, AIDS research and human retroviruses.

Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses.

J. Routy, P. Hétu, Johanne Poudrier, 2023, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations

J. Routy, A. Finzi, N. Brassard, 2023, Current issues in molecular biology.

The Influence of Oral Terbinafine on Gut Fungal Microbiome Composition and Microbial Translocation in People Living with HIV Treated for Onychomycosis

J. Routy, S. Isnard, C. Costiniuk, 2023, Journal of fungi.

Material deprivation is associated with liver stiffness and liver-related outcomes in people with HIV.

J. Routy, A. de Pokomandy, N. Kronfli, 2024, Liver international : official journal of the International Association for the Study of the Liver.