D. Garvey

发表

(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.

D. Donnelly-roberts, S. Arneric, J. Sullivan, 1994, The Journal of pharmacology and experimental therapeutics.

Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: nitric oxide-donor naproxen prodrugs.

V. Dhawan, D. Garvey, D. Janero, 2006, Bioorganic & medicinal chemistry.

Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.

D. Donnelly-roberts, Y. Martin, S. Arneric, 1996, Journal of medicinal chemistry.

Synthesis and structure-activity relationship of novel, highly potent metharyl and methcycloalkyl cyclooxygenase-2 (COX-2) selective inhibitors.

David R Janero, D. Garvey, R. Earl, 2003, Journal of medicinal chemistry.

Use of highly reactive, versatile and air-stable palladium-phosphinous acid complex [(t-Bu)2P(OH)]2PdCl2 (popd) as a catalyst for the optimized Suzuki-Miyaura cross-coupling of less reactive heteroaryl chlorides and arylboronic acids

D. Garvey, S. P. Khanapure, 2004 .

Cyclopentanedi- and tricarboxylic acids as squalene synthase inhibitors: syntheses and evaluation.

D. Garvey, S. Rosenberg, W. Shen, 1998, Bioorganic & medicinal chemistry letters.

Novel isoxazoles which interact with brain cholinergic channel receptors have intrinsic cognitive enhancing and anxiolytic activities.

S. Arneric, J. Sullivan, D. Garvey, 1994, Journal of medicinal chemistry.

Combination of paclitaxel and nitric oxide as a novel treatment for the reduction of restenosis.

D. Garvey, D. Janero, L. Letts, 2004, Journal of medicinal chemistry.

3,4-Disubstituted .gamma.-lactam rings as conformationally constrained mimics of peptide derivatives containing aspartic acid or norleucine

D. Garvey, P. D. May, A. Nadzan, 1990 .

NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor

D. Garvey, R. Earl, D. Janero, 2006, InflammoPharmacology.

Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers.

D. Garvey, D. Janero, L. Letts, 2007, Current topics in medicinal chemistry.

Nitrosylated bovine serum albumin derivatives as pharmacologically active nitric oxide congeners.

D. Garvey, D. Janero, D. Young, 1997, The Journal of pharmacology and experimental therapeutics.

Preparation of functionalized tertiary thiols and nitrosothiols

D. Garvey, Tiansheng Wang, S. Richardson, 2006 .

S-nitrosylated tissue-type plasminogen activator protects against myocardial ischemia/reperfusion injury in cats: role of the endothelium.

A. M. Lefer, D. Garvey, A. Lefer, 1996, The Journal of pharmacology and experimental therapeutics.

Design of Cholecystokinin Analogs with High Affinity and Selectivity for Brain CCK Receptors

D. Garvey, M. Holladay, A. Nadzan, 1992 .

Highly Stereoselective Aldol Condensation Using an Enantioselective Chiral Enolate

D. Garvey, S. Ali, S. Masamune, 1980 .

l-Cysteine as a water-soluble cation scavenger in the removal of the 2,4,6-trimethoxybenzyl group from thiols

D. Garvey, S. Richardson, Chia-En Lin, 2002 .

3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.

D. Garvey, R. Earl, D. Janero, 2004, Bioorganic & medicinal chemistry letters.

A Short, Efficient Synthesis of the Novel Cholinergic Channel Activator, ABT 418, from L-Proline

D. Garvey, N. Lin, Yun He, 1995 .

Ligands for brain cholinergic channel receptors: synthesis and in vitro characterization of novel isoxazoles and isothiazoles as bioisosteric replacements for the pyridine ring in nicotine.

D. Anderson, D. Garvey, N. Lin, 1994, Journal of medicinal chemistry.

Di‐n‐butylboryl Trifluoromethanesulfonate

D. Garvey, J. Methot, E. Flamme, 2004 .

Synthesis and in vitro characterization of novel amino terminally modified oxotremorine derivatives for brain muscarinic receptors.

D. Anderson, E. Cadman, D. Garvey, 1992, Journal of medicinal chemistry.

Synthesis and selective cyclooxygenase-2 (COX-2) inhibitory activity of a series of novel bicyclic pyrazoles.

D. Garvey, D. Janero, L. Letts, 2004, Bioorganic & medicinal chemistry.

Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles.

D. Garvey, R. Earl, D. Janero, 2004, Journal of medicinal chemistry.

Aldol methodology: synthesis of versatile intermediates, 3-hydroxy-2-vinylcarbonyl compounds

D. Garvey, S. Masamune, T. Kaiho, 1983 .

Total synthesis of 6-deoxyerythronolide B

D. Garvey, M. Hirama, S. Ali, 1981 .

Aldol methodology: synthesis of versatile intermediates, 3-hydroxy-2-vinylcarbonyl compounds

D. Garvey, S. Masamune, T. Kaiho, 1982 .

Use of the E-vinyloxyborane derived from S-phenyl propanethioate for stereospecific aldol-type condensation. A simplified synthesis of the prelog-djerassi lactonic acid

D. Garvey, M. Hirama, S. Masamune, 1980 .

Structure-based design, synthesis, and biological evaluation of indomethacin derivatives as cyclooxygenase-2 inhibiting nitric oxide donors.

D. Garvey, D. Janero, J. Ellis, 2007, Journal of medicinal chemistry.

An efficient synthesis of 2-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-d]azepines

D. Garvey, G. M. Carrera, C. Hutchins, 1991 .

Synthesis of ansamycins: the ansa chain of rifamycin S

B. Imperiali, D. Garvey, S. Masamune, 1982 .

trans-3-n-propyl-L-proline is a highly favorable, conformationally restricted replacement for methionine in the C-terminal tetrapeptide of cholecystokinin. Stereoselective synthesis of 3-allyl- and 3-n-propyl-L-proline derivatives from 4-hydroxy-L-proline.

D. Garvey, M. Holladay, A. Nadzan, 1991, Journal of medicinal chemistry.

Synthesis of novel substituted spirohydantoins

D. Garvey, G. M. Carrera, 1992 .

Practical, Efficient Synthesis of β-Amino Tertiary Thiols via Aminolysis Ring-Opening of Thiiranes

D. Garvey, X. Fang, Qing Dong, 1999 .

The in vitro hepatic metabolism of ABT-418, a cholinergic channel activator, in rats, dogs, cynomolgus monkeys, and humans.

A. D. Rodrigues, J. Sullivan, D. Garvey, 1994, Drug metabolism and disposition: the biological fate of chemicals.

A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: In Vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand

D. Donnelly-roberts, D. Mckenna, S. Arneric, 1996, Neuropharmacology.

Structure-activity studies on a novel series of cholinergic channel activators based on a heteroaryl ether framework.

S. Arneric, J. Sullivan, D. Garvey, 1999, Bioorganic & medicinal chemistry letters.

Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.

A. D. Rodrigues, D. Donnelly-roberts, S. Arneric, 1997, Journal of medicinal chemistry.

2-(Aryloxymethyl) azacyclic analogues as novel nicotinic acetylcholine receptor (nAChR) ligands

S. Arneric, J. Sullivan, D. Garvey, 1996 .

Synthesis of the Nakanishi Ring-Locked Retinoid

Jamie B. Côté, Tan D. Quach, Andrey P. Demenev, 2011, International journal of medicinal chemistry.

Nitric oxide-based molecular strategies for restenosis therapy

D. Garvey, D. Janero, Chia-En Lin, 2005 .

A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods.

V. Dhawan, D. Garvey, R. Earl, 2005, Biochemical pharmacology.

Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence.

D. Garvey, P. Cuevas, L. Letts, 1999, The Journal of pharmacology and experimental therapeutics.

Nitrosothiol esters of diclofenac: synthesis and pharmacological characterization as gastrointestinal-sparing prodrugs.

D. Garvey, D. Janero, L. Letts, 2000, Journal of medicinal chemistry.

(1 alpha, 2 beta, 3 beta, 4 alpha)-1,2-bis[N-propyl-N-(4-phenoxybenzyl) amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): a novel potent squalene synthase inhibitor.

D. Garvey, S. Rosenberg, S. Fakhoury, 1997, Journal of medicinal chemistry.

Nitrosothiol-based NO-donors inhibit the gastrointestinal mucosal damaging actions of NSAIDs

D. Garvey, D. Janero, L. Letts, 2004, InflammoPharmacology.

First examples of oxidizing secondary alcohols to ketones in the presence of the disulfide functional group: synthesis of novel diketone disulfides.

D. Garvey, U. Bandarage, T. Wang, 2001, Journal of Organic Chemistry.

9‐Borabicyclononyl Trifluoromethanesulfonate

D. Garvey, E. Theodorakis, Heesoon Lee, 2006 .

A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand.

D. Mckenna, S. Arneric, J. Sullivan, 1996, Neuropharmacology.

ABT-418: A Novel Cholinergic Channel Activator (ChCA) for the Potential Treatment of Alzheimer’s Disease

A. D. Rodrigues, S. Arneric, J. Sullivan, 1994 .

ABT — 418, a Novel Nicotinic Agonist

A. D. Rodrigues, W. J. Jackson, Y. Martin, 1994 .