E. F. da Cruz e Silva

发表

Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides.

P. Greengard, A. Nairn, J. Girault, 1995, Biochemical and biophysical research communications.

The alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines.

P. Greengard, E. F. da Cruz e Silva, C. Ouimet, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Αβ Hinders Nuclear Targeting of AICD and Fe65 in Primary Neuronal Cultures

E. F. da Cruz e Silva, S. Vieira, O. D. C. E. Silva, 2009, Journal of Molecular Neuroscience.

Complexing Aβ Prevents the Cellular Anomalies Induced by the Peptide Alone

E. F. da Cruz e Silva, R. Ruivo, O. A. B. da Cruz e Silva, 2014, Journal of Molecular Neuroscience.

Tyrosine 687 Phosphorylated Alzheimer’s Amyloid Precursor Protein Is Retained Intracellularly and Exhibits a Decreased Turnover Rate

J. Wiltfang, E. F. da Cruz e Silva, S. Vieira, 2007, Neurodegenerative Diseases.

Protein phosphatase 1 is a key player in nuclear events.

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, F. Martins, 2015, Cellular signalling.

Evidence for a role of protein phosphatases 1 and 2A during early nephrogenesis.

E. F. da Cruz e Silva, A. Aperia, M. Durbeej, 1995, Kidney international.

Alternative Splicing Controls Nuclear Translocation of the Cell Cycle-regulated Nek2 Kinase*

E. F. da Cruz e Silva, M. Fardilha, A. Knebel, 2007, Journal of Biological Chemistry.

Intracellular sAPP retention in response to Aβ is mapped to cytoskeleton‐associated structures

E. F. da Cruz e Silva, S. Vieira, M. Crespo-López, 2009, Journal of neuroscience research.

Primate sperm contain protein phosphatase 1, a biochemical mediator of motility.

P. Greengard, E. F. da Cruz e Silva, D. Wolf, 1996, Biology of reproduction.

The Nuclear Envelope Protein, LAP1B, Is a Novel Protein Phosphatase 1 Substrate

E. F. da Cruz e Silva, M. Fardilha, W. Dauer, 2013, PloS one.

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

J. Wiltfang, S. Small, E. F. da Cruz e Silva, 2010, Molecular Neurodegeneration.

A Model System to Study Intracellular Trafficking and Processing of the Alzheimer’s Amyloid Precursor Protein

E. F. da Cruz e Silva, S. Vieira, O. A. B. da Cruz e Silva, 2004, Neurodegenerative Diseases.

RanBP9 modulates AICD localization and transcriptional activity via direct interaction with Tip60.

R. Nitsch, E. F. da Cruz e Silva, M. Fardilha, 2014, Journal of Alzheimer's disease : JAD.

SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein.

E. F. da Cruz e Silva, M. Fardilha, G. Browne, 2007, The Biochemical journal.

Drosophila contains three genes that encode distinct isoforms of protein phosphatase 1.

E. F. da Cruz e Silva, L. Alphey, P. Cohen, 1990, European journal of biochemistry.

Progesterone regulates the phosphorylation of protein phosphatases in the brain

E. F. da Cruz e Silva, L. Garcia-Segura, C. Guerra-Araiza, 2010, Journal of neuroscience research.

Protein phosphatase 2Bw and protein phosphatase Z are Saccharomyces cerevisiae enzymes.

E. F. da Cruz e Silva, M. Stark, P. Cohen, 1991, Biochimica et biophysica acta.

Isolation of a cDNA likely to encode a novel Ca2+-dependent/calmodulin-stimulated protein phosphatase.

E. F. da Cruz e Silva, P. Cohen, 1989, Biochimica et biophysica acta.

Isolation and sequence analysis of a cDNA clone encoding a type‐1 protein phosphatase catalytic subunit: Homology with protein phosphatase 2A

P. Cohen, E. F. da Cruz e Silva, D. Campbell, 1987, FEBS letters.

The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen

E. F. da Cruz e Silva, M. Fardilha, C. Cunha, 2011, Virology Journal.

Isolation and sequence analysis of a cDNA clone encoding the entire catalytic subunit of phosphorylase kinase

E. F. da Cruz e Silva, P. Cohen, 1987, FEBS letters.

Enhanced generation of Alzheimer’s amyloid‐β following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C

P. Greengard, E. F. da Cruz e Silva, S. Gandy, 2009, Journal of neurochemistry.

Monitoring ``De Novo'' APP Synthesis by Taking Advantage of the Reversible Effect of Cycloheximide

E. F. da Cruz e Silva, S. Vieira, O. A. B. da Cruz e Silva, 2009, American journal of Alzheimer's disease and other dementias.

Altered Subcellular Distribution of the Alzheimer's Amyloid Precursor Protein Under Stress Conditions

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, A. G. Henriques, 2007, Annals of the New York Academy of Sciences.

Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.

P. Greengard, A. Nairn, P. Greengardt, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Expression and characterization of the tau subunit of phosphorylase kinase.

C. Yuan, E. F. da Cruz e Silva, A. Myers, 1989, Biochemical and biophysical research communications.

Differential Distribution of Alzheimer's Amyloid Precursor Protein Family Variants in Human Sperm

E. F. da Cruz e Silva, M. Fardilha, M. Sousa, 2007, Annals of the New York Academy of Sciences.

Identification of a novel protein phosphatase catalytic subunit by cDNA cloning

E. F. da Cruz e Silva, P. Cohen, O. da Cruz e Silva, 1988, FEBS letters.

Characterisation of several ankyrin repeat protein variant 2, a phosphoprotein phosphatase 1-interacting protein, in testis and spermatozoa.

E. F. da Cruz e Silva, M. Fardilha, J. Silva, 2016, Reproduction, fertility, and development.

In vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements.

E. F. da Cruz e Silva, J. Ferreira, S. Vieira, 2010, Journal of biomedical materials research. Part B, Applied biomaterials.

Identification of the human testis protein phosphatase 1 interactome.

Margarida Fardilha, Luís Korrodi-Gregório, E. F. da Cruz e Silva, 2011, Biochemical pharmacology.

Biological responses of brushite-forming Zn- and ZnSr- substituted beta-tricalcium phosphate bone cements.

E. F. da Cruz e Silva, J. Ferreira, S. Vieira, 2010, European cells & materials.

Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity.

P. Greengard, E. F. da Cruz e Silva, S. Vijayaraghavan, 1996, Biology of reproduction.

An Intriguing Shift Occurs in the Novel Protein Phosphatase 1 Binding Partner, TCTEX1D4: Evidence of Positive Selection in a Pika Model

E. F. da Cruz e Silva, M. Fardilha, S. Afonso, 2013, PloS one.

In Vivo Interaction of the Hepatitis Delta Virus Small Antigen with the ELAV-Like Protein HuR

E. F. da Cruz e Silva, M. Fardilha, C. Cunha, 2011, The open virology journal.

Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa

E. F. da Cruz e Silva, M. Fardilha, S. Vijayaraghavan, 2013, BMC Cell Biology.

BRI2 and BRI3 are functionally distinct phosphoproteins.

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, F. Martins, 2016, Cellular signalling.

Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13.

E. F. da Cruz e Silva, D. Sheer, N. Spurr, 1990, Genomics.

Genetic mutations strengthen functional association of LAP1 with DYT1 dystonia and muscular dystrophy.

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, S. Rebelo, 2015, Mutation research. Reviews in mutation research.

Identification of a Novel Human LAP1 Isoform That Is Regulated by Protein Phosphorylation

E. F. da Cruz e Silva, T. Muller, K. Marcus, 2014, PloS one.

LAP1 is a crucial protein for the maintenance of the nuclear envelope structure and cell cycle progression

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, F. Martins, 2014, Molecular and Cellular Biochemistry.

Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility.

E. F. da Cruz e Silva, M. Fardilha, S. Pelech, 2011, Molecular human reproduction.

Wnt signalling is a relevant pathway contributing to amyloid beta- peptide-mediated neuropathology in Alzheimer's disease.

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, A. G. Henriques, 2010, CNS & neurological disorders drug targets.

Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, S. Rebelo, 2004, Journal of neuroscience research.

Aβ promotes Alzheimer’s disease‐like cytoskeleton abnormalities with consequences to APP processing in neurons

E. F. da Cruz e Silva, S. Vieira, O. A. B. da Cruz e Silva, 2010, Journal of neurochemistry.

Protein Phosphatase 1γ Isoforms Linked Interactions in the Brain

E. F. da Cruz e Silva, M. Fardilha, L. Korrodi-Gregório, 2012, Journal of Molecular Neuroscience.

Identification of a novel complex AβPP:Fe65:PP1 that regulates AβPP Thr668 phosphorylation levels.

E. F. da Cruz e Silva, M. Fardilha, S. Vieira, 2013, Journal of Alzheimer's disease : JAD.

PP1 inhibition by Abeta peptide as a potential pathological mechanism in Alzheimer's disease.

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, A. G. Henriques, 2009, Neurotoxicology and teratology.

Protein phosphatase 1α interacting proteins in the human brain.

E. F. da Cruz e Silva, M. Fardilha, O. A. B. da Cruz e Silva, 2012, Omics : a journal of integrative biology.

Amyloid precursor protein interaction network in human testis: sentinel proteins for male reproduction

José F. F. Mendes, Alexander V. Goltsev, Joana Silva, 2015, BMC Bioinformatics.

Preparation and characterization of recombinant protein phosphatase 1.

P. Greengard, A. Nairn, E. F. da Cruz e Silva, 2003, Methods in enzymology.

Protein Phosphorylation and APP Metabolism

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, 2003, Neurochemical research.

Sodium azide and 2-deoxy-D-glucose-induced cellular stress affects phosphorylation-dependent AbetaPP processing.

Margarida Fardilha, E. F. da Cruz e Silva, M. Fardilha, 2005, Journal of Alzheimer's disease : JAD.

TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network

E. F. da Cruz e Silva, M. J. Freitas, M. Fardilha, 2013, Biology Open.

Localisation of the gene encoding the catalytic gamma subunit of phosphorylase kinase to human chromosome bands 7p12-q21.

E. F. da Cruz e Silva, D. Sheer, N. Spurr, 1990, Biochimica et biophysica acta.

Complexing Aβ Prevents the Cellular Anomalies Induced by the Peptide Alone

E. F. da Cruz e Silva, R. Ruivo, O. A. B. da Cruz e Silva, 2014, Journal of Molecular Neuroscience.

"Omics" of human sperm: profiling protein phosphatases.

E. F. da Cruz e Silva, M. Fardilha, S. Pelech, 2013, Omics : a journal of integrative biology.

Monitoring protein phosphatase 1 isoform levels as a marker for cellular stress.

E. F. da Cruz e Silva, O. A. B. da Cruz e Silva, A. G. Henriques, 2004, Neurotoxicology and teratology.

Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform

E. F. da Cruz e Silva, M. Fardilha, O. A. B. da Cruz e Silva, 2011, Journal of neurochemistry.