A. Gilman

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The Catalytic Mechanism of Mammalian Adenylyl Cyclase

C. Dessauer, A. Gilman, 1997, The Journal of Biological Chemistry.

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.

S. Sprang, A. Gilman, M. Wall, 1995, Cell.

The structure of the G protein heterotrimer Giα1 β 1 γ 2

S. Sprang, A. Gilman, M. Wall, 1995, Cell.

G proteins.

A. Gilman, M. Linder, 1992, Scientific American.

Allosteric determinants in guanine nucleotide-binding proteins

Rama Ranganathan, R. Ranganathan, S. W. Lockless, 2003, Proceedings of the National Academy of Sciences of the United States of America.

G proteins: transducers of receptor-generated signals.

A. Gilman, A G Gilman, 1987, Annual review of biochemistry.

Structure of RGS4 Bound to AlF4 −-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

S. Sprang, A. Gilman, J. Tesmer, 1997, Cell.

Adenosine cyclic 3',5'-monophosphate in fetal rat brain cell cultures. I. Effect of catecholamines.

A. Gilman, B. Schrier, B. Schrier, 1972, Molecular pharmacology.

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.

A. Gilman, J. Northup, M. Smigel, 1982, The Journal of biological chemistry.

Chromatographic resolution and immunologic identification of the alpha 40 and alpha 41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain.

A. Gilman, P. Sternweis, S. Mumby, 1988, The Journal of biological chemistry.

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.

A. Gilman, E. Ross, P. Sternweis, 1987, The Journal of biological chemistry.

The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.

A. Gilman, M. Smigel, T. Higashijima, 1987, The Journal of biological chemistry.

Regulation of cyclic AMP metabolism in cultured cells of the nervous system.

A. Gilman, 1972, Advances in cyclic nucleotide research.

Purification and characterization of smooth muscle cell caveolae

N. Hooper, A. Gilman, J. de Gunzburg, 1994, The Journal of cell biology.

Role of the β-Adrenergic Receptor in the Regulation of Adenylate Cyclase

A. Gilman, E. Ross, M. Smigel, 1984 .

Receptor regulation of G-protein palmitoylation.

A. Gilman, S. Mumby, C. Kleuss, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Regulators of G Protein Signaling 6 and 7

A. Gilman, B. Posner, B. A. Harris, 1999, The Journal of Biological Chemistry.

RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha.

A. Gilman, J. Hepler, T. Kozasa, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Mutations of GS alpha designed to alter the reactivity of the protein with bacterial toxins. Substitutions at ARG187 result in loss of GTPase activity.

A. Gilman, M. Freissmuth, 1989, The Journal of biological chemistry.

Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.

M. Simon, A. Gilman, P. Sternweis, 1993, Proceedings of the National Academy of Sciences of the United States of America.

beta-Adrenergic receptor: ligand binding properties and the interaction with adenylyl cyclase.

M. Maguire, A. Gilman, E. Ross, 1977, Advances in cyclic nucleotide research.

Deduced primary structure of the cr-subunit of the GTP-binding stimulatory protein of adenylate cyclase (guanine nucleotide-binding regulatory proteins/transducin/ras proteins)

A. Gilman, B. A. Harris, J. Robishaw, 2016 .

Sequestration of the G protein βγ subunit complex inhibits receptor-mediated endocytosis

Hsin C. Lin, A. Gilman, T. Kozasa, 1998 .

A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.

A. Gilman, M. Wall, B. Snow, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha.

A. Gilman, M. Graziano, Michael P. Graziano, 1989, The Journal of biological chemistry.

Time resolved kinetics of direct G beta 1 gamma 2 interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits.

N. Davidson, C. Dessauer, A. Gilman, 1996, Neuropharmacology.

Mechanism of GTP hydrolysis by G-protein alpha subunits.

S. Sprang, A. Gilman, E. Lee, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.

A. Gilman, P. Sternweis, 1979, The Journal of biological chemistry.

Beta adrenergic receptors and adenylate cyclase: products of separate genes?

H. Bourne, P. Insel, M. Maguire, 1976, Molecular pharmacology.

The regulatory components of adenylate cyclase and transducin. A family of structurally homologous guanine nucleotide-binding proteins.

A. Gilman, D. Manning, David, 1983, The Journal of biological chemistry.

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

A. Gilman, G. Bokoch, 1984, Cell.

GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits.

A. Gilman, T. Wilkie, D. M. Berman, 1996, Cell.

Regulation of Dynamin I GTPase Activity by G Protein βγ Subunits and Phosphatidylinositol 4,5-Bisphosphate*

Hsin C. Lin, A. Gilman, H. Lin, 1996, The Journal of Biological Chemistry.

TAO (Thousand-and-one Amino Acid) Protein Kinases Mediate Signaling from Carbachol to p38 Mitogen-activated Protein Kinase and Ternary Complex Factors*

A. Gilman, M. Cobb, Sheu-Fen Lee, 2003, Journal of Biological Chemistry.

Stimulation of cyclic AMP accumulation by 2 chloroadenosine: lack of incorporation of nucleoside into cyclic nucleotides

A. Gilman, T. Sturgill, B. Schrier, 1975 .

Regulation of Adenosine 3′,5′-Cyclic Monophosphate Metabolism in Cultured Neuroblastoma Cells

M. Nirenberg, A. Gilman, 1971, Nature.

Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

R. Kahn, A. Gilman, S. Mumby, 1986, Proceedings of the National Academy of Sciences of the United States of America.

G-protein a-subunit expression , myristoylation , and membrane association in COS cells ( protein N-myristoylation / fatty acid analog )

A. Gilman, S. Mumby, Robert 0. HEUKEROTHt, 2022 .

The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution, activity, and properties of the 35,000-dalton (beta) subunit.

A. Gilman, P. Sternweis, J. Northup, 1983, The Journal of biological chemistry.

Nobel Lecture. G proteins and regulation of adenylyl cyclase.

A. Gilman, 1995, Bioscience reports.

Hydrodynamic properties of the beta-adrenergic receptor and adenylate cyclase from wild type and varient S49 lymphoma cells.

A. Gilman, T. Haga, K. Haga, 1977, The Journal of biological chemistry.

Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.

M. Maguire, A. Gilman, R. Wiklund, 1976, The Journal of biological chemistry.

Reconstitution of catecholamine-sensitive adenylate cyclase. Association of a regulatory component of the enzyme with membranes containing the catalytic protein and beta-adrenergic receptors.

A. Gilman, P. Sternweis, A. Howlett, 1979, The Journal of biological chemistry.

G protein βγ subunits: Simplified purification and properties of novel isoforms

A. Gilman, J. Iñiguez-Lluhí, Ethan Lee, 1994 .

ADP-ribosylation of transducin by islet-activation protein. Identification of asparagine as the site of ADP-ribosylation.

R. Kahn, A. Gilman, B. Fraser, 1984, The Journal of biological chemistry.

Isolation and Characterization of Constitutively Active Mutants of Mammalian Adenylyl Cyclase*

R. Sunahara, A. Gilman, M. Hatley, 2000, The Journal of Biological Chemistry.

Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.

D. Russell, A. Gilman, B. A. Harris, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase.

R. Kahn, A. Gilman, P. Sternweis, 1982, The Journal of biological chemistry.

Characteristics of the guanine nucleotide-binding regulatory component of adenylate cyclase.

A. Gilman, J. Northup, M. Smigel, 1982, Recent progress in hormone research.

Receptor-regulated G proteins

A. Gilman, 1986, Trends in Neurosciences.

Cyclic Adenosine Monophosphate and Alteration of Chinese Hamster Ovary Cell Morphology: a Rapid, Sensitive In Vitro Assay for the Enterotoxins of Vibrio cholerae and Escherichia coli

A. Gilman, L. Brunton, L. Rebhun, 1974, Infection and immunity.

ADP-ribosylation of Gs promotes the dissociation of its alpha and beta subunits.

R. Kahn, A. Gilman, 1984, The Journal of biological chemistry.

The regulatory component of adenylate cyclase. Purification and properties.

A. Gilman, P. Sternweis, J. Northup, 1981, The Journal of biological chemistry.

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.

T. Katada, A. Gilman, G. Bokoch, 1984, The Journal of biological chemistry.

G proteins.

A. Gilman, J. Hepler, 1992, Trends in biochemical sciences.

Mechanisms of guanine nucleotide-mediated regulation of adenylate cyclase activity.

T. Katada, A. Gilman, G. Bokoch, 1984, Advances in cyclic nucleotide and protein phosphorylation research.

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.

A. Gilman, E. Ross, T. Haga, 1977, Proceedings of the National Academy of Sciences of the United States of America.

[16] Purification of recombinant G(q)α, G11α, and G16α from Sf9 cells

A. Gilman, J. Hepler, T. Kozasa, 1994 .

Expression and purification of recombinant adenylyl cyclases in Sf9 cells.

R. Taussig, A. Gilman, W. Tang, 1994, Methods in enzymology.

Crystallization of complex between soluble domains of adenylyl cyclase and activated Gs alpha.

S. Sprang, R. Sunahara, A. Gilman, 2002, Methods in enzymology.

Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells.

A. Gilman, S. Mumby, Chunfa Huang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Autoacylation of G protein alpha subunits.

A. Gilman, J. Duncan, 1996, The Journal of biological chemistry.

The G protein β2 complementary DNA encodes the β35 subunit

A. Gilman, S. Mumby, B. Gao, 1987 .

Lipid Modifications of G Protein Subunits MYRISTOYLATION OF Go, INCREASES ITS AFFINITY FOR By*

J. Gordon, A. Gilman, P. Sternweis, 2001 .

Characterization of Saccharomyces cerevisiaeAcyl-protein Thioesterase 1, the Enzyme Responsible for G Protein α Subunit Deacylation in Vivo *

A. Gilman, J. Duncan, 2002, The Journal of Biological Chemistry.

The importance of G-protein beta lambda subunits.

A. Gilman, J. Iñiguez-Lluhí, C. Kleuss, 1993, Trends in cell biology.

Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.

T. Katada, A. Gilman, E. Ross, 1984, The Journal of biological chemistry.

Guanine nucleotide-binding regulatory proteins: a family of membrane-bound transducers

R. Kahn, A. Gilman, 1984 .

Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.

A. Gilman, S. Gibson, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Efficiency of coupling between the beta adrenergic receptor and adenylate cyclase.

A. Gilman, A. Howlett, P. V. Van Arsdale, 1978, Molecular pharmacology.

Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.

P. Casey, A. Gilman, M. Graziano, 1987, The Journal of biological chemistry.

Structural and Biochemical Characterization of the GTP γ S-, GDP ‚ Pi-, and GDP-Bound Forms of a GTPase-Deficient Gly 42 f Val Mutant of Gi R 1 †

S. Sprang, A. Gilman, D. Coleman, 1997 .

Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes.

A. Gilman, G. Tall, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Assay of cyclic nucleotides by receptor protein binding displacement.

F. Murad, A. Gilman, 1974, Methods in enzymology.

Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: a simultaneous protein binding assay.

F. Murad, A. Gilman, 1971, Biochimica et biophysica acta.

Regulation of mammalian adenylyl cyclases by G-protein α and βγ subunits

A. Gilman, J. Iñiguez-Lluhí, S. Mumby, 1992 .

Norepinephrine Stimulated Increase of Cyclic AMP Levels in Developing Mouse Brain Cell Cultures

A. Gilman, N. Seeds, 1971, Science.

Transmembrane signaling, G proteins, and adenylyl cyclase.

A. Gilman, 1989, Harvey lectures.

Hydrodynamic properties of the regulatory component of adenylate cyclase.

A. Gilman, A. Howlett, 1980, The Journal of biological chemistry.

Activation of transducin guanosine triphosphatase by two proteins of the RGS family.

H. Hamm, V. Arshavsky, A. Gilman, 1997, Biochemistry.

Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.

S. Sprang, A. Gilman, D. Coleman, 1997, Biochemistry.

Adenylyl cyclases

A. Gilman, Wei Tang, 1992, Cell.

Inhibition of the omega-conotoxin-sensitive calcium current by distinct G proteins.

R. Taussig, A. Gilman, F. Belardetti, 1992, Neuron.

Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis.

S. Sprang, A. Gilman, A. Berghuis, 1995, Science.

Regulation of purified type I and type II adenylylcyclases by G protein beta gamma subunits.

R. Taussig, A. Gilman, L. Quarmby, 1993, The Journal of biological chemistry.

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.

S. Sprang, A. Gilman, A. Berghuis, 1994, Science.

Biochemical properties of hormone-sensitive adenylate cyclase.

A. Gilman, E. Ross, 1980, Annual review of biochemistry.

A protein binding assay for adenosine 3':5'-cyclic monophosphate.

A. Gilman, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Purification of Recombinant G Proteins from Sf9 Cells by Hexahistidine Tagging of Associated Subunits

A. Gilman, T. Kozasa, 1995, The Journal of Biological Chemistry.

G protein beta gamma subunits. Simplified purification and properties of novel isoforms.

A. Gilman, E. Lee, J. Iñiguez-Lluhí, 1994, The Journal of biological chemistry.

Expression of G-protein alpha subunits in Escherichia coli.

A. Gilman, E. Lee, Ethan Lee, 1994, Methods in enzymology.

G proteins.

A. Gilman, J. Hepler, A G Gilman, 1992, Trends in biochemical sciences.

The GTPase-activating Protein RGS4 Stabilizes the Transition State for Nucleotide Hydrolysis*

A. Gilman, T. Kozasa, D. M. Berman, 1996, The Journal of Biological Chemistry.

Interaction of the two cytosolic domains of mammalian adenylyl cyclase.

C. Dessauer, A. Gilman, R. Whisnant, 1996, Proceedings of the National Academy of Sciences of the United States of America.

19F and 31P NMR spectroscopy of G protein alpha subunits. Mechanism of activation by Al3+ and F-.

A. Gilman, M. Kainosho, M. Graziano, 1991, The Journal of biological chemistry.

Factors influencing adenosine 3',5'-phosphate accumulation in bovine thyroid slices.

A. Gilman, T. Rall, 1968, The Journal of biological chemistry.

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

C. Barnes, P. Worley, A. Gilman, 1998, The Journal of Neuroscience.

Fluorescent Modification of Adenosine 3',5'-Monophosphate: Spectroscopic Properties and Activity in Enzyme Systems

J. Barrio, A. Gilman, C. Villar-Palasi, 1972, Science.

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

A. Gilman, E. Ross, A. Howlett, 1978, The Journal of biological chemistry.

Resolution of some components of adenylate cyclase necessary for catalytic activity.

A. Gilman, E. Ross, A. G. Gilman, 1977, The Journal of biological chemistry.

Giα and Gβ subunits both define selectivity of G protein activation by α2-adrenergic receptors

A. Gilman, S. Gibson, 2006 .

Selective Regulation of Gαq/11 by an RGS Domain in the G Protein-coupled Receptor Kinase, GRK2*

C. Carman, A. Gilman, J. Benovic, 1999, The Journal of Biological Chemistry.

Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.

T. Katada, A. Gilman, G. Bokoch, 1984, The Journal of biological chemistry.

[18] Purification of recombinant G1α and Goα proteins from Escherichia coli

A. Gilman, M. Linder, 1991 .

G proteins and regulation of adenylyl cyclase

A. Gilman, 1989 .

Molecular cloning of complementary DNA for the alpha subunit of the G protein that stimulates adenylate cyclase.

A. Gilman, B. A. Harris, S. Mumby, 1985, Science.

Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase.

Y. Watanabe, K. Jakobs, T. Katada, 1985, European journal of biochemistry.

Guanine-Nucleotide-Binding Regulatory Proteins

A. Gilman, G. Bokoch, J. Robishaw, 1985 .

Mammalian Membrane-bound Adenylyl Cyclases (*)

R. Taussig, A. Gilman, 1995, The Journal of Biological Chemistry.

The Reaction of [3H]Norepinephrine with Particulate Fractions of Cells Responsive to Catecholamines

M. Maguire, A. Gilman, P. Goldmann, 1974 .

Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase.

A. Gilman, 1984, The Journal of clinical investigation.

G proteins and dual control of adenylate cyclase

A. Gilman, 1984, Cell.

ADP-RIBOSYLATION OF THE REGULATORY COMPONENTS OF ADENYLATE CYCLASE1,2

T. Katada, R. Kahn, A. Gilman, 1983 .

G protein involvement in receptor-effector coupling.

P. Casey, A. Gilman, A G Gilman, 1988, The Journal of biological chemistry.

Identification of the predominant substrate for ADP-ribosylation by islet activating protein.

E. Hewlett, T. Katada, A. Gilman, 1983, The Journal of biological chemistry.

The Albert Lasker Medical Awards. G proteins and regulation of adenylyl cyclase.

A. Gilman, Alfred G. Gilman, 1989, JAMA.

G proteins control diverse pathways of transmembrane signaling 1

P. Casey, A. Gilman, M. Freissmuth, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Protein binding assays for cyclic nucleotides.

A. Gilman, 1972, Advances in cyclic nucleotide research.

Homologies between signal transducing G proteins and ras gene products.

J B Hurley, M. Simon, J. Hurley, 1984, Science.

Frustration and adenylate cyclase.

M. Maguire, A. Gilman, T. Sturgill, 1975, Metabolism: clinical and experimental.

Relationship between the beta-adrenergic receptor and adenylate cyclase.

M. Maguire, A. Gilman, E. Ross, 1977, The Journal of biological chemistry.

Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding.

M. Maguire, A. Gilman, 1974, Biochimica et biophysica acta.

The role of adenosine 3',5'-phosphate in mediating effects of thyroid-stimulating hormone on carbohydrate metabolism of bovine thyroid slices.

A. Gilman, T. Rall, 1968, The Journal of biological chemistry.

G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma.

M. Simon, A. Gilman, Melvin I. Simon, 1992, The Journal of biological chemistry.

Influence of gamma subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes.

A. Gilman, P. Sternweis, S. Mumby, 1992, Molecular biology of the cell.

Hormone receptors and the control of cyclic AMP metabolism in parental and hybrid somatic cells.

M. Maguire, A. Gilman, L. Brunton, 1976, Recent progress in hormone research.

Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.

A. Gilman, P. Sternweis, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.

S R Sprang, S. Sprang, R. Sunahara, 1997, Science.

Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits.

M. Simon, A. Gilman, Melvin I. Simon, 1993, The Journal of biological chemistry.

Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel

D. Clapham, R. Taussig, A. Gilman, 1994, Nature.

Functional Importance of the Amino Terminus of G(*)

A. Gilman, E. Ross, J. Hepler, 1996, The Journal of Biological Chemistry.

Cloning and expression of a widely distributed (type IV) adenylyl cyclase.

A. Gilman, B. Gao, Boning Gao, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Mammalian RGS Proteins: Barbarians at the Gate*

A. Gilman, D. M. Berman, 1998, The Journal of Biological Chemistry.

Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure.

C. Slaughter, A. Gilman, Wei-Jen Tang, 1989, Science.

[19] Synthetic peptide antisera with determined specificity for G protein α or β subunits

A. Gilman, S. Mumby, 1991 .

Molecular basis for two forms of the G protein that stimulates adenylate cyclase.

A. Gilman, J. Robishaw, M. Smigel, 1986, The Journal of biological chemistry.

GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain*

R. Lefkowitz, A. Gilman, B. Snow, 1998, The Journal of Biological Chemistry.

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.

P C Sternweis, A. Gilman, P. Sternweis, 1998, Science.

A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits

A. Gilman, M. Wall, B. Snow, 1998 .

Crystal structure of the adenylyl cyclase activator Gsalpha.

S. Sprang, R. Sunahara, A. Gilman, 1997, Science.

Splice variants of the alpha subunit of the G protein Gs activate both adenylyl cyclase and calcium channels.

A. Brown, A. Gilman, L. Birnbaumer, 1989, Science.

An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.

M. Maguire, A. Gilman, P. V. Van Arsdale, 1976, Molecular pharmacology.

Complexity and diversity of mammalian adenylyl cyclases.

R. Sunahara, C. Dessauer, A. Gilman, 1996, Annual review of pharmacology and toxicology.

Guanine nucleotide-binding regulatory proteins; mediators of transmembrane signaling

A. Gilman, M. Graziano, 1987 .

Organization of G proteins and adenylyl cyclase at the plasma membrane.

A. Gilman, S. Mumby, J. Hepler, 1997, Molecular biology of the cell.

Tertiary and Quaternary Structural Changes in Giα1 Induced by GTP Hydrolysis

S. Sprang, A. Gilman, A. Berghuis, 1995, Science.

G Proteins and Regulation of Adenylate Cyclase (Nobel Lecture)

A. Gilman, 1995 .

A Protein BindingAssayforAdenosine 3':5'-Cyclic Monophosphate

A. Gilman, 1970 .

Binding of (3H)prostaglandin E1 to putative receptors linked to adenylate cyclase of cultured cell clones.

A. Gilman, L. Brunton, R. Wiklund, 1976, The Journal of biological chemistry.

The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.

R. Kahn, A. Gilman, Gilman, 1986, The Journal of biological chemistry.

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and the inhibition of adenylate cyclase in S49 lymphoma cyc- and wild type membranes.

T. Katada, A. Gilman, G. Bokoch, 1984, The Journal of biological chemistry.

Inhibition of adenylyl cyclase by Gi alpha.

R. Taussig, A. Gilman, J. Iñiguez-Lluhí, 1993, Science.

Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits.

A. Gilman, Wei-Jen Tang, W. J. Tang, 1991, Science.

A Cytoplasmic Acyl-Protein Thioesterase That Removes Palmitate from G Protein α Subunits and p21RAS *

A. Gilman, J. Duncan, 1998, The Journal of Biological Chemistry.

A Candidate Target for G Protein Action in Brain*

A. Gilman, T. Kozasa, Linda T. Chen, 1999, The Journal of Biological Chemistry.

p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13

A. Gilman, P. Sternweis, G. Bollag, 1998 .

G protein gamma subunits contain a 20-carbon isoprenoid.

P. Casey, A. Gilman, P. Sternweis, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Expression and analysis of Gs alpha mutants with decreased ability to activate adenylylcyclase.

A. Gilman, H. Itoh, 1991, The Journal of biological chemistry.

Inhibition of an inwardly rectifying K+ channel by G-protein α-subunits

H. Lester, N. Davidson, C. Dessauer, 1996, Nature.

Inhibition of an inwardly rectifying K+ channel by G-protein α-subunits

H. Lester, N. Davidson, C. Dessauer, 1996, Nature.

Erratum: Inhibition of an inwardly rectifying K+ channel by G-protein α-subunits (Nature (1996) 380 (624-627))

H. Lester, N. Davidson, C. Dessauer, 1996 .

The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.

A. Gilman, M. Smigel, T. Higashijima, 1986, The Journal of biological chemistry.

Lipid modifications of G protein subunits. Myristoylation of Go alpha increases its affinity for beta gamma.

J. Gordon, A. Gilman, P. Sternweis, 1991, The Journal of biological chemistry.

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.

P C Sternweis, A. Gilman, P. Sternweis, 1998, Science.

Two-metal-Ion catalysis in adenylyl cyclase.

S R Sprang, S. Sprang, R. Sunahara, 1999, Science.

Cyclic Adenosine Monophosphate andAlteration ofChinese Hamster OvaryCellMorphology: aRapid, Sensitive InVitro AssayfortheEnterotoxins ofVibrio cholerae and Escherichia coli

A. Gilman, L. Brunton, T. Schnaitman, 1974 .

Mammalian Ric-8A (Synembryn) Is a Heterotrimeric Gα Protein Guanine Nucleotide Exchange Factor*

A. Gilman, G. Tall, A. Krumins, 2003, The Journal of Biological Chemistry.

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

A. Gilman, T. Wilkie, D. M. Berman, 1996, Cell.

Persistent membrane association of activated and depalmitoylated G protein α subunits

A. Gilman, S. Mumby, Chunfa Huang, 1999 .

Autoacylation of G Protein α Subunits*

A. Gilman, J. Duncan, 1996, The Journal of Biological Chemistry.

[17] Purification of recombinant Gsα

A. Gilman, M. Freissmuth, M. Graziano, 1991 .

Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins.

A. Gilman, P. Sternweis, M. Smigel, 1987, The Journal of biological chemistry.

Gsalpha contains an unidentified covalent modification that increases its affinity for adenylyl cyclase.

A. Gilman, C. Kleuss, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

M. Simon, P. Casey, A. Gilman, 1990, The Journal of biological chemistry.

Exchange of Substrate and Inhibitor Specificities between Adenylyl and Guanylyl Cyclases*

S. Sprang, R. Sunahara, A. Gilman, 1998, The Journal of Biological Chemistry.

Molecular basis for P-site inhibition of adenylyl cyclase.

S R Sprang, S. Sprang, R. Sunahara, 2000, Biochemistry.

Synthetic peptide antisera with determined specificity for G protein alpha or beta subunits.

A. Gilman, S. Mumby, 1991, Methods in enzymology.

Activation of phospholipase C-β2 mutants by G protein αq and βγ subunits

A. Gilman, Seokmin Shin, S. Rhee, 1993 .

Assay of G-protein beta gamma-subunit complex by catalytic support of ADP-ribosylation of Go alpha.

P. Casey, A. Gilman, I. Pang, 1991, Methods in enzymology.

The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit.

A. Gilman, P. Sternweis, J. Northup, 1983, The Journal of biological chemistry.

The importance of G-protein βλ subunits

A. Gilman, J. Iñiguez-Lluhí, C. Kleuss, 1993 .

The interactions of adenylate cyclases with P-site inhibitors.

S. Sprang, C. Dessauer, A. Gilman, 1999, Trends in pharmacological sciences.

Identification of a Giα Binding Site on Type V Adenylyl Cyclase*

S. Sprang, C. Dessauer, A. Gilman, 1998, The Journal of Biological Chemistry.

Interaction of Gsα with the Cytosolic Domains of Mammalian Adenylyl Cyclase*

R. Sunahara, C. Dessauer, A. Gilman, 1997, The Journal of Biological Chemistry.

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

R. Miller, A. Gilman, M. Linder, 1990, The Journal of biological chemistry.

Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons.

M. Nirenberg, A. Gilman, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Role of G proteins in transmembrane signaling.

P. Casey, A. Gilman, M. Freissmuth, 1988, Cold Spring Harbor symposia on quantitative biology.

Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.

R. Taussig, A. Gilman, Wei-Jen Tang, 1994, The Journal of biological chemistry.

A second form of the beta subunit of signal-transducing G proteins.

A. Gilman, J. Robishaw, B. Gao, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.

T. Katada, A. Gilman, G. Bokoch, 1984, The Journal of biological chemistry.

Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.

P. Casey, A. Gilman, S. Mumby, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.

R. Kahn, A. Gilman, Gilman, 1984, The Journal of biological chemistry.

Purification and functional analysis of Ric-8A: A guanine nucleotide exchange factor for G-protein α subunits

A. Gilman, G. Tall, 2004 .

Lipid Modification of G Proteins: alpha Subunits are Palmitoylated

R. Taussig, A. Gilman, S. Mumby, 1993 .

Inhibition of the ω-conotoxin-sensitive calcium current by distinct G proteins

R. Taussig, A. Gilman, F. Belardetti, 1992, Neuron.

Targeted Knockdown of G Protein Subunits Selectively Prevents Receptor-mediated Modulation of Effectors and Reveals Complex Changes in Non-targeted Signaling Proteins*

A. Gilman, A. Krumins, 2006, Journal of Biological Chemistry.

Assay of RGS protein activity in vitro using purified components.

A. Gilman, A. Krumins, 2002, Methods in enzymology.

Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.

A. Gilman, P. Feinstein, J. Krupinski, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins.

A. Gilman, E. Ross, M. Smigel, 1985, The Journal of biological chemistry.

The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits.

R. Taussig, A. Gilman, E. Lee, 1992, The Journal of biological chemistry.

Time Resolved Kinetics of Direct Gβ1γ2 Interactions with the Carboxyl Terminus of Kir3.4 Inward Rectifier K+ Channel Subunits

H. Lester, N. Davidson, C. Dessauer, 1996, Neuropharmacology.

G protein beta gamma subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of alpha subunits by pertussis toxin but differential interactions with Gs alpha.

P. Casey, A. Gilman, M. Graziano, 1989, Biochemistry.

Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.

J. Minna, A. Gilman, 1973, The Journal of biological chemistry.

Expression and characterization of calmodulin-activated (type I) adenylylcyclase.

A. Gilman, J. Krupinski, W J Tang, 1991, The Journal of biological chemistry.

Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.

A. Gilman, E. Ross, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Control of adenylate cyclase activity by G proteins.

A. Gilman, M. Smigel, K. M. Ferguson, 1985, Advances in cyclic nucleotide and protein phosphorylation research.

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.

J. Gordon, A. Gilman, S. Mumby, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Purification and Characterization of a Soluble Form of Mammalian Adenylyl Cyclase*

C. Dessauer, A. Gilman, 1996, The Journal of Biological Chemistry.

Expression of Gs alpha in Escherichia coli. Purification and properties of two forms of the protein.

A. Gilman, M. Freissmuth, M. Graziano, 1989, The Journal of biological chemistry.

Protein Kinase C Phosphorylates G12α and Inhibits Its Interaction with Gβγ(*)

A. Gilman, T. Kozasa, 1996, The Journal of Biological Chemistry.

Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.

A. Gilman, B. Posner, E. Ross, 1999, Biochemistry.

Activation of phospholipase C-beta 2 mutants by G protein alpha q and beta gamma subunits.

A. Gilman, S. Rhee, J. Hepler, 1993, The Journal of biological chemistry.

Structure of the GDP–Pi complex of Gly203→Ala Giα1: a mimic of the ternary product complex of Gα-catalyzed GTP hydrolysis

S. Sprang, A. Gilman, A. Berghuis, 1996 .

Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes.

A. Gilman, G. Tall, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Purification of recombinant Gq alpha, G11 alpha, and G16 alpha from Sf9 cells.

A. Gilman, J. Hepler, T. Kozasa, 1994, Methods in Enzymology.

Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure.

T. Smith, E. Neer, A. Gilman, 1998, The Journal of biological chemistry.

Persistent membrane association of activated and depalmitoylated G protein alpha subunits.

A. Gilman, S. Mumby, J. Duncan, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Interactions of Forskolin and ATP with the Cytosolic Domains of Mammalian Adenylyl Cyclase*

C. Dessauer, A. Gilman, Tracy T. Scully, 1997, The Journal of Biological Chemistry.

Construction of a soluble adenylyl cyclase activated by Gs alpha and forskolin.

A. Gilman, W. J. Tang, Wei-Jen Tang, 1995, Science.

Truncation and alanine-scanning mutants of type I adenylyl cyclase.

A. Gilman, Wei-Jen Tang, M. Stanzel, 1995, Biochemistry.

Sites Important for PLCβ2 Activation by the G Protein βγ Subunit Map to the Sides of the β Propeller Structure*

Temple F. Smith, E. Neer, A. Gilman, 1998, The Journal of Biological Chemistry.

Sites for Gα Binding on the G Protein β Subunit Overlap with Sites for Regulation of Phospholipase Cβ and Adenylyl Cyclase*

Temple F. Smith, E. Neer, A. Gilman, 1998, The Journal of Biological Chemistry.

Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis.

S. Sprang, A. Gilman, A. Berghuis, 1996, Structure.

Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases.

R. Sunahara, A. Gilman, M. Hatley, 2002, Methods in enzymology.

The A326S Mutant of Giα1 as an Approximation of the Receptor-bound State*

S. Sprang, A. Gilman, M. Wall, 1998, Journal of Biological Chemistry.

Gia1: Stabilization of the Transition State for GTP Hydrolysis

S. Sprang, A. Gilman, J. Tesmer, 1997 .

Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein alpha subunits.

A. Gilman, G. Tall, 2004, Methods in enzymology.

Regulation of adenylyl cyclase by G proteins.

A. Gilman, 1990, Advances in second messenger and phosphoprotein research.

Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel.

D. Clapham, R. Taussig, A. Gilman, 1994, Nature.

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.

S. Sprang, R. Sunahara, A. Gilman, 1997, Science.

Drug transporters in drug efficacy and toxicity.

P. Sexton, R. Kim, R. Lefkowitz, 2012, Annual review of pharmacology and toxicology.

Purification of the regulatory component of adenylate cyclase.

A. Gilman, E. Ross, P. Sternweis, 1980, Proceedings of the National Academy of Sciences of the United States of America.

The crystallographic structure of a G protein heterotrimer

S. Sprang, A. Gilman, M. Wall, 1996 .

Adenylyl cyclases

A. Gilman, Wei Tang, 1992, Cell.

Crystallization and preliminary crystallographic studies of Giα1 and mutants of Giα1 in the GTP and GDP-bound states

S. Sprang, A. Gilman, A. Berghuis, 1994 .

The guanine nucleotide-binding regulatory component of adenylate cyclase in human erythrocytes.

A. Gilman, E. Hanski, 1982, Journal of cyclic nucleotide research.