D. McKinzie

发表

Diverse Psychotomimetics Act Through a Common Signaling Pathway

P. Greengard, P. Svenningsson, A. Fienberg, 2003, Science.

Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.

D. McKinzie, S. D. Kahl, M. Statnick, 2011, Journal of medicinal chemistry.

Effects of taste aversion training on the acquisition of alcohol drinking in adolescent P and HAD rat lines.

W. Mcbride, L. Lumeng, T. Li, 1996, Alcoholism, clinical and experimental research.

Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice

J. Wess, C. Deng, F. Bymaster, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Use of M1–M5 Muscarinic Receptor Knockout Mice as Novel Tools to Delineate the Physiological Roles of the Muscarinic Cholinergic System

Christian C. Felder, J. Wess, F. Bymaster, 2003, Neurochemical Research.

Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia.

Craig Mallinckrodt, Anantha Shekhar, Christian C Felder, 2008, The American journal of psychiatry.

3-(4-Chloro-2-Morpholin-4-yl-Thiazol-5-yl)-8-(1-Ethylpropyl)-2,6-Dimethyl-Imidazo[1,2-b]Pyridazine: A Novel Brain-Penetrant, Orally Available Corticotropin-Releasing Factor Receptor 1 Antagonist with Efficacy in Animal Models of Alcoholism

P. Hipskind, D. McKinzie, C. Hamdouchi, 2007, The Journal of Neuroscience.

Pharmacological and Pharmacokinetic Properties of a Structurally-Novel , Potent , Selective mGlu 2 / 3 Receptor Agonist : In Vitro Characterization of LY 404039

G. Marek, E. Nisenbaum, D. McKinzie, 2007 .

Pharmacological and Pharmacokinetic Properties of a Structurally Novel, Potent, and Selective Metabotropic Glutamate 2/3 Receptor Agonist: In Vitro Characterization of Agonist (–)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic Acid (LY404039)

G. Marek, E. Nisenbaum, D. McKinzie, 2007, Journal of Pharmacology and Experimental Therapeutics.

Improved Bioavailability of the mGlu2/3 Receptor Agonist LY354740 Using a Prodrug Strategy: In Vivo Pharmacology of LY544344

D. McKinzie, D. Schoepp, L. Rorick-Kehn, 2006, Journal of Pharmacology and Experimental Therapeutics.

Improved Bioavailability of the mGlu 2 / 3 Receptor Agonist LY 354740 Using a Prodrug Strategy : In Vivo Pharmacology of LY 544344

D. McKinzie, D. Schoepp, L. Rorick-Kehn, 2005 .

Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulator.

D. McKinzie, S. Iyengar, B. Clark, 2013, Bioorganic & medicinal chemistry letters.

Translational Neuroimaging: Substance Abuse Disorders

A. Schwarz, D. McKinzie, M. Plawecki, 2012 .

S. Hunt, D. Hommer, D. Economidou, 2009, Alcohol.

The M1/M4 agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain

A. Schwarz, D. McKinzie, A. Gozzi, 2020, bioRxiv.

Synthesis and pharmacological characterization of 4-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates: identification of new potent and selective metabotropic glutamate 2/3 receptor agonists.

G. Stephenson, D. McKinzie, M. Bures, 2013, Journal of medicinal chemistry.

Sobs Annual Report | | 2008 80 Primary

J. Whisstock, P. Taylor, L. Poston, 2022 .

Development of alcohol drinking behavior in rat lines selectively bred for divergent alcohol preference.

W. Mcbride, L. Lumeng, T. Li, 1998, Alcoholism, clinical and experimental research.

Reduction in Muscarinic M1-Mediated Hypercholinergic State and Beneficial Cognitive Effects of Muscarinic Agonists in Schizophrenia

F. Bymaster, D. McKinzie, S. Lazareno, 2009 .

Bassoon contributes to tau-seed propagation and neurotoxicity

G. Viana di Prisco, J Zhang, A. Mosley, 2022, Nature Neuroscience.

NAALADase inhibition reduces alcohol consumption in the alcohol‐preferring (P) line of rats

W. Mcbride, T. Li, D. McKinzie, 2000, Addiction biology.

Discovery of a novel series of orally active nociceptin/orphanin FQ (NOP) receptor antagonists based on a dihydrospiro(piperidine-4,7'-thieno[2,3-c]pyran) scaffold.

D. McKinzie, S. D. Kahl, J. Witkin, 2014, Journal of medicinal chemistry.

SUGGESTIONS FROM THE INFANT RAT ABOUT BRAIN DYSFUNCTION AND MEMORY

N. Spear, D. McKinzie, M. Arnold, 1994 .

Chronic pain impairs cognitive flexibility and engages novel learning strategies in rats

Stephen L. Cowen, D. McKinzie, E. Navratilova, 2018, Pain.

New evidence for the involvement of muscarinic cholinergic receptors in psychoses

F. Bymaster, D. McKinzie, C. Felder, 2004 .

Effects of ethanol consumption by adolescent alcohol-preferring P rats on subsequent behavioral performance in the cross-maze and slip funnel tests.

Ting-kai Li, W. Mcbride, L. Lumeng, 1996, Alcohol.

Patterns of ethanol and saccharin intake in P rats under limited-access conditions.

W. Mcbride, D. McKinzie, J. Murphy, 1999, Alcohol.

Determining Pharmacological Selectivity of the Kappa Opioid Receptor Antagonist LY2456302 Using Pupillometry as a Translational Biomarker in Rat and Human

J. Suico, D. McKinzie, J. McKinzie, 2015, The international journal of neuropsychopharmacology.

The alcohol deprivation effect in the alcohol-preferring P rat under free-drinking and operant access conditions.

Ting-kai Li, W. Mcbride, L. Lumeng, 1998, Alcoholism, clinical and experimental research.

Sensitivity and tolerance to the motor impairing effects of moderate doses of ethanol

W. Mcbride, D. McKinzie, R. Bell, 2000, Pharmacology Biochemistry and Behavior.

Effects of amphetamine on locomotor activity in adult and juvenile alcohol-preferring and -nonpreferring rats

Ting-kai Li, W. Mcbride, L. Lumeng, 2002, Pharmacology Biochemistry and Behavior.

In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

K. Perry, D. McKinzie, J. Witkin, 2007, Psychopharmacology.

Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of female Wistar rats

W. Mcbride, D. McKinzie, James M. Murphy, 2000, Psychopharmacology.

Muscarinic mechanisms in psychotic disorders.

F. Bymaster, D. McKinzie, David L McKinzie, 2012, Handbook of experimental pharmacology.

Muscarinic mechanisms of antipsychotic atypicality

Christian C. Felder, F. Bymaster, E. Tzavara, 2003, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine‐induced seizure activity

J. Wess, F. Bymaster, D. McKinzie, 2003, The European journal of neuroscience.

Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice

J. Wess, F. Bymaster, E. Tzavara, 2003, Molecular Psychiatry.

The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain

A. Schwarz, D. McKinzie, A. Gozzi, 2020, Neuropsychopharmacology.

Genetic Background and Sex: Impact on Generalizability of Research Findings in Pharmacology Studies.

S. McTighe, D. McKinzie, S. J. Sukoff Rizzo, 2019, Handbook of experimental pharmacology.

Effects of 5-HT(3) receptor antagonists on daily alcohol intake under acquisition, maintenance, and relapse conditions in alcohol-preferring (P) rats.

W. Mcbride, L. Lumeng, T. Li, 2000, Alcohol.

Raloxifene reduces sex- and age-related intervertebral disc degeneration in mice by estrogen signaling

Joseph M. Wallace, D. McKinzie, A. Berman, 2021, bioRxiv.

Acoustic Startle and Fear-Potentiated Startle in Alcohol-Preferring (P) and -Nonpreferring (NP) Lines of Rats

W. Mcbride, L. Lumeng, D. McKinzie, 2000, Pharmacology Biochemistry and Behavior.

Hedonic and motivational responses to food reward are unchanged in rats with neuropathic pain

Stephen L. Cowen, D. McKinzie, E. Navratilova, 2016, Pain.

Effects of prenatal exposure to cocaine on heart rate and nonassociative learning and retention in infant rats.

C. Heyser, N. Spear, D. McKinzie, 1994, Teratology.

Quantitative autoradiography of mu-opioid receptors in the CNS of alcohol-naive alcohol-preferring P and -nonpreferring NP rats.

W. Mcbride, L. Lumeng, T. Li, 1998, Alcohol.

Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective

D. McKinzie, D. Clawson, S. Atwell, 2015, Journal of medicinal chemistry.

Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain struct

D. McKinzie, D. Clawson, S. Atwell, 2015, Journal of medicinal chemistry.

Pharmacotherapy of Alcohol Dependence: Improving Translation from the Bench to the Clinic

E. Sellers, D. McKinzie, M. Shram, 2008 .

The long-lasting effects of JDTic, a kappa opioid receptor antagonist, on the expression of ethanol-seeking behavior and the relapse drinking of female alcohol-preferring (P) rats

W. Mcbride, D. McKinzie, F. Carroll, 2012, Pharmacology Biochemistry and Behavior.

Autonomic activation associated with ethanol self-administration in adult female P rats

Ting-kai Li, W. Mcbride, L. Lumeng, 2008, Pharmacology Biochemistry and Behavior.

Effects of ethanol on startle responding in alcohol-preferring and -non-preferring rats

W. Mcbride, L. Lumeng, D. McKinzie, 2000, Pharmacology Biochemistry and Behavior.

The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent on repeated deprivations.

W. Mcbride, L. Lumeng, T. Li, 2000, Alcoholism, clinical and experimental research.

Alcohol deprivation effect is prolonged in the alcohol preferring (P) rat after repeated deprivations.

Ting-kai Li, W. Mcbride, L. Lumeng, 2000, Alcoholism, clinical and experimental research.

Voluntary ethanol drinking during the first three postnatal weeks in lines of rats selectively bred for divergent ethanol preference.

W. Mcbride, L. Lumeng, T. Li, 1999, Alcoholism, clinical and experimental research.

Metabotropic Glutamate 2/3 Receptor Agonists and Positive Allosteric Modulators of Metabotropic Glutamate Receptor 2 as Novel Agents for the Treatment of Schizophrenia

G. Marek, D. McKinzie, B. Kinon, 2012 .

Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)

E. Nisenbaum, D. McKinzie, D. Schoepp, 2005, Psychopharmacology.

Serotonin3 receptor antagonism of alcohol intake: effects of drinking conditions.

W. Mcbride, L. Lumeng, T. Li, 1998, Alcohol.

Pharmacologic Interactions between the Muscarinic Cholinergic and Dopaminergic Systems in the Modulation of Prepulse Inhibition in Rats

D. McKinzie, H. Shannon, C. Jones, 2005, Journal of Pharmacology and Experimental Therapeutics.

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders

D. McKinzie, Xia Li, J. Witkin, 2014, Neuropharmacology.

The Muscarinic Acetylcholine Receptor Agonist BuTAC Mediates Antipsychotic-Like Effects via the M4 Subtype

D. McKinzie, C. Felder, L. Rorick-Kehn, 2013, Neuropsychopharmacology.

M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related central nervous system pathologies

J. Wess, K. Perry, F. Bymaster, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Muscarinic Acetylcholine Receptor Knockout Mice

Christian C. Felder, Yinghong Cui, Tsuyoshi Miyakawa, 2004 .

Elucidating the role of muscarinic receptors in psychosis.

F. Bymaster, D. McKinzie, C. Felder, 2001, Life sciences.

Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia

D. McKinzie, K. Svensson, J. Monn, 2012, Neuropharmacology.

Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands

D. McKinzie, L. Rorick-Kehn, J. Hart, 2005, Psychopharmacology.

Exploratory Analysis for a Targeted Patient Population Responsive to the Metabotropic Glutamate 2/3 Receptor Agonist Pomaglumetad Methionil in Schizophrenia

D. McKinzie, B. Kinon, B. Millen, 2015, Biological Psychiatry.

Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species

R. Dean, D. McKinzie, L. L. Winneroski, 2022, Journal of Alzheimer's disease reports.

Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors

Janice W. Smith, D. McKinzie, J. Pintar, 2016, Pharmacology research & perspectives.

Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy

D. McKinzie, Nur Jury, C. Lasagna-Reeves, 2021, Neurobiology of Aging.

MEASUREMENT OF ENDOGENOUS MOUSE TAU IN CEREBROSPINAL FLUID FROM AGED PDAPP MICE FOLLOWING TREATMENT WITH AB-LOWERING COMPOUNDS

D. McKinzie, R. Demattos, D. Riddell, 2018, Alzheimer's & Dementia.

A CORRELATIONAL ANALYSIS OF EXPOSURE AND PHARMACODYNAMIC EFFECTS OF THE BACE1 INHIBITOR LY3202626 IN PDAPP MICE FOLLOWING ACUTE ORAL DOSING

D. McKinzie, L. L. Winneroski, P. May, 2016, Alzheimer's & Dementia.

Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats.

W. Mcbride, D. McKinzie, S. Hauser, 2012, Alcohol.

The Orexin-1 Receptor Antagonist SB-334867 Reduces Alcohol Relapse Drinking, but not Alcohol-Seeking, in Alcohol-Preferring (P) Rats

W. Mcbride, D. McKinzie, S. Hauser, 2010, Journal of addiction medicine.

The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-administration in alcohol-preferring (P) rats

W. Mcbride, D. McKinzie, D. Schoepp, 2006, Behavioural Brain Research.

Low-dose stimulatory effects of ethanol during adolescence in rat lines selectively bred for high alcohol intake.

W. Mcbride, L. Lumeng, D. McKinzie, 2004, Alcoholism, clinical and experimental research.

Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.

Ben Grayson, John M Schaus, F. Bymaster, 2010, The international journal of neuropsychopharmacology.

Ontogenetic differences in variability on simple measures of learning: theoretical and practical implications.

M. Wenger, D. McKinzie, Michael J. Wenger, 1996, Developmental psychobiology.

Ontogenetic differences in the expression of conditioned stimulus conditioning: effects of retention interval.

N. Spear, D. McKinzie, W. J. Chen, 1998, Behavioral neuroscience.

A fostering study of the effects of prenatal cocaine exposure: II. Offspring behavioral measures.

C. Heyser, N. Spear, V. Molina, 1992, Neurotoxicology and teratology.

Prenatal and postnatal ethanol exposure influences preweanling rats' behavioral and autonomic responding to ethanol odor.

N. Spear, D. McKinzie, J. C. Molina, 1996, Alcohol.

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

P. Sexton, A. Christopoulos, D. McKinzie, 2010, Neuropsychopharmacology.

Melanin-Concentrating Hormone-1 Receptor Modulates Neuroendocrine, Behavioral, and Corticolimbic Neurochemical Stress Responses in Mice

D. McKinzie, G. Nomikos, J. Witkin, 2006, Neuropsychopharmacology.

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

A. Christopoulos, F. Bymaster, D. McKinzie, 2008, Proceedings of the National Academy of Sciences.

An Assessment of Novelty-Seeking Behavior in Alcohol-Preferring and Nonpreferring Rats

W. Mcbride, L. Lumeng, D. McKinzie, 2000, Pharmacology Biochemistry and Behavior.

Additive reduction of alcohol drinking by 5-HT1A antagonist WAY 100635 and serotonin uptake blocker fluoxetine in alcohol-preferring P rats.

L. Lumeng, T. Li, D. McKinzie, 1998, Alcoholism, clinical and experimental research.

Intersensory integration in the infant rat.

N. Spear, D. McKinzie, 1994 .

Effects of kappa opioid receptor agonists on attention as assessed by a 5-choice serial reaction time task in rats

D. McKinzie, M. Statnick, C. Mitch, 2007, Neuropharmacology.

Alcohol-Mediated Tactile Conditioned Aversions in Infant Rats: Devaluation of Conditioning through Alcohol-Sucrose Associations

N. Spear, H. Arnold, D. McKinzie, 1996, Neurobiology of Learning and Memory.

Microglial knockdown does not affect acute withdrawal but delays analgesic tolerance from oxycodone in male and female C57BL/6J mice

D. McKinzie, A. Oblak, Timothy B Meyer, 2022, Advances in Drug and Alcohol Research.

Muscarinic Acetylcholine Receptors as Novel Targets for the Development of Therapeutics for Schizophrenia

D. McKinzie, Bin Liu, C. Felder, 2012 .

Muscarinic receptors as a target for drugs treating schizophrenia.

F. Bymaster, D. McKinzie, C. Felder, 2002, Current drug targets. CNS and neurological disorders.

Reduction of dendritic spines and elevation of GABAergic signaling in the brains of mice treated with an estrogen receptor β ligand

J. Gustafsson, D. McKinzie, V. Krishnan, 2012, Proceedings of the National Academy of Sciences.

Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor.

D. McKinzie, D. Timm, L. L. Winneroski, 2021, Journal of medicinal chemistry.

Pharmacological Characterization of LY593093, an M1 Muscarinic Acetylcholine Receptor-Selective Partial Orthosteric Agonist

S. Hitchcock, D. McKinzie, Bin Liu, 2011, Journal of Pharmacology and Experimental Therapeutics.

Procholinergic and memory enhancing properties of the selective norepinephrine uptake inhibitor atomoxetine

K. Perry, F. Bymaster, E. Tzavara, 2006, Molecular Psychiatry.

Role for M5 muscarinic acetylcholine receptors in cocaine addiction

J. Wess, A. Fink-Jensen, D. McKinzie, 2003, Journal of neuroscience research.

Cocaine Is Self‐administered into the Shell Region of the Nucleus Accumbens in Wistar Rats

W. Mcbride, D. McKinzie, J. Murphy, 1999, Annals of the New York Academy of Sciences.

Cocaine Is Self-Administered into the Shell but Not the Core of the Nucleus Accumbens of Wistar Rats

Ting-kai Li, W. Mcbride, D. McKinzie, 2002, Journal of Pharmacology and Experimental Therapeutics.

Further Characterization of Multi-Organ DEARE and Protection by 16,16 Dimethyl Prostaglandin E2 in a Mouse Model of the Hematopoietic Acute Radiation Syndrome

D. McKinzie, Daohong Zhou, A. Bhatwadekar, 2023, Radiation Research.

Ontogenetic differences in ethanol-induced impairment of context and CS learning

N. Spear, D. McKinzie, Jieun Lee, 1996, Psychobiology.

Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats

W. Mcbride, D. McKinzie, James M. Murphy, 2002, Psychopharmacology.

Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M₁ agonists.

S. Hitchcock, F. Bymaster, B. Liu, 2015, Bioorganic & medicinal chemistry letters.

In Vitro and in Vivo Evidence for a Lack of Interaction with Dopamine D2 Receptors by the Metabotropic Glutamate 2/3 Receptor Agonists 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-bicaroxylate Monohydrate (LY354740) and (−)-2-Oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic Acid (LY379268)

G. Marek, K. Perry, D. McKinzie, 2009, Journal of Pharmacology and Experimental Therapeutics.

Effects of a novel mGlu2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

R. Dean, K. Perry, D. McKinzie, 2012, Psychopharmacology.

Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3 Receptor Agon

K. Adragni, D. McKinzie, D. Clawson, 2018, Journal of Medicinal Chemistry.

Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects

D. McKinzie, G. Gilmour, J. Witkin, 2017, Pharmacology Biochemistry and Behavior.

Translational Pharmacology of the Metabotropic Glutamate 2 Receptor–Preferring Agonist LY2812223 in the Animal and Human Brain

E. Nisenbaum, D. McKinzie, C. Felder, 2017, Journal of Pharmacology and Experimental Therapeutics.

Translational pharmacology of the mGluR 2-preferring agonist LY 2812223 in animal and human brain

E. Nisenbaum, D. McKinzie, C. Felder, 2017 .

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

A. Christopoulos, D. McKinzie, S. Lazareno, 2008, Proceedings of the National Academy of Sciences.

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders

D. McKinzie, Xia Li, J. Witkin, 2014, Neuropharmacology.

Ontogenetic differences in conditioning to context and CS as a function of context saliency and CS-US interval

N. Spear, D. McKinzie, 1995 .

Pharmacological Characterization of LY593093, an M1 Muscarinic Acetylcholine Receptor-Selective Partial Orthosteric Agonist

S. Hitchcock, D. McKinzie, Bin Liu, 2011, Journal of Pharmacology and Experimental Therapeutics.

Effects of a novel mGlu2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

R. Dean, K. Perry, D. McKinzie, 2011, Psychopharmacology.