T. Hambley

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P. Comba, T. Hambley, 2007 .

Molecular mechanics modelling of Pt/nucleotide and Pt/DNA interactions

Trevor W. Hambley, T. Hambley, 2001 .

The chemistry of cobalt acetate—IV. The isolation and crystal structure of the symmetric cubane, tetrakis[(μ-acetato)(μ3-oxo) (pyridine)cobalt(III)] · chloroform solvate, [Co4(μ3-O)4(μ-CH3CO2)4(C5H5N)in4] · 5CHCl3 and of the dicationic partial cubane, trimeric, [(μ-acetato)(acetato)tris(μ-hdyroxy(μ3

T. Hambley, A. Masters, J. Beattie, 1998 .

The chemistry of cobalt acetate—III. The isolation and crystal structure characterisation of the mixed valence octacobalt oligomer, [Co8(O)4(CH3CO2)6(OMe)4]Cl4(OHn)4 · 6H2O (n = 1 or 2), derived from the preparation of cobalt(III) acetate

T. Hambley, A. Masters, J. Beattie, 1997 .

The chemistry of cobalt acetate: The isolation and crystal structure of the symmetric trimer,hexakis(μ-acetato)-μ3-oxo-tris(pyridine)tricobalt(III) perchlorate water solvate, [Co3O(CH3CO2)6(C5H5N)3][CiO4]·H2O

T. Hambley, A. Masters, J. Beattie, 1996 .

The Influence of the Axial Ligands of a Series of Platinum(IV) Anti-Cancer Complexes on Their Reduction to Platinum(II) and Reaction With DNA

T. Hambley, L. T. Ellis, H. Er, 1995 .

Slowing of cisplatin aquation in the presence of DNA but not in the presence of phosphate: improved understanding of sequence selectivity and the roles of monoaquated and diaquated species in the binding of cisplatin to DNA.

T. Hambley, S. Berners‐Price, M. Davies, 2000, Inorganic chemistry.

Platinum binding to DNA: structural controls and consequences

T. Hambley, 2001 .

Studies of the binding of a series of platinum(IV) complexes to plasma proteins.

T. Hambley, G. Deacon, Rachael C. Dolman, 2002, Journal of inorganic biochemistry.

Cytotoxic efficacy of an anthraquinone linked platinum anticancer drug.

T. Hambley, R. Callaghan, H. Mellor, 2006, Biochemical pharmacology.

Comparative efficacy of novel platinum(IV) compounds with established chemotherapeutic drugs in solid tumour models.

M. Hall, D. Ferguson, T. Hambley, 2004, Biochemical pharmacology.

Elemental tomography of cancer-cell spheroids reveals incomplete uptake of both platinum(II) and platinum(IV) complexes.

S. Sutton, M. Hall, T. Hambley, 2007, Journal of the American Chemical Society.

Harnessing the properties of cobalt coordination complexes for biological application

T. Hambley, E. New, Elizabeth J. New, 2017, Coordination Chemistry Reviews.

NMR and structural studies of gold(I) chloride adducts with bidentate 2-, 3- and 4-pyridyl phosphines

T. Hambley, S. Berners‐Price, P. Healy, 1999 .

Transporter and protease mediated delivery of platinum complexes for precision oncology

T. Hambley, 2019, JBIC Journal of Biological Inorganic Chemistry.

Studies of a cobalt(III) complex of the MMP inhibitor marimastat: a potential hypoxia-activated prodrug.

T. Hambley, T. Failes, C. Cullinane, 2007, Chemistry.

Studies on pyridazine azide cyclisation reactions.

D. Hibbs, J. Hanrahan, T. Hambley, 2004, Organic & biomolecular chemistry.

Conformational analysis of group IVB aryls: An electric birefringence and molecular mechanics study

T. Hambley, G. W. Allen, M. Aroney, 1990 .

Physiological Targeting to Improve Anticancer Drug Selectivity

T. Hambley, 2008 .

Solid state and solution structures of two structurally related dicopper complexes with markedly different redox properties

P. Comba, T. Hambley, D. Richens, 1996 .

Quantitative measurement of the reduction of platinum(IV) complexes using X-ray absorption near-edge spectroscopy (XANES).

M. Hall, T. Hambley, Jenny Z. Zhang, 2012, Metallomics : integrated biometal science.

Crystal structure of (azacapten)cobalt(II) diperchlorate and strain energy minimization analyses of the (azacapten)cobalt(III) and (azacapten)cobalt(II) cations (azacapten = 1-methyl-3,13,16-trithia-6,8,10-19-tetraazabicyclo[6.6.6]eicosane)

M. R. Snow, T. Hambley, 1986 .

Strain energy minimization study of the mechanism of, and the barrier to, conformational interconversion in five‐membered diamine chelate rings

T. Hambley, 1987 .

Theoretical analysis of the cobalt(III)-cobalt(II) tris[(.+-.)-1,2-propanediamine] electron-transfer reaction using molecular mechanics modeling of the configurational isomer distribution in both oxidation states

M. R. Snow, A. Bond, T. Hambley, 1987 .

Macrochelate complexes of purine 5'-nucleotide triphosphates and monophosphates: definitive multinuclear NMR evidence supported by molecular mechanics calculations

T. Hambley, L. Marzilli, M. Reily, 1988 .

Rates of platination of -AG- and -GA- containing double-stranded oligonucleotides: effect of chloride concentration.

T. Hambley, S. Berners‐Price, M. Davies, 2000, Journal of inorganic biochemistry.

Use of .beta.-sulfonyl vinyl ketones as equivalents to vinyl ketones in the Robinson annelation. Convergent, highly stereoselective preparation of a hydrindanol related to vitamin D from 2-methylcyclopent-2-enone and lithiated (E)-but-2-enyldiphenylphosphine oxide

T. Hambley, R. Haynes, S. C. Vonwiller, 1989 .

A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake

T. Hambley, M. Simone, A. Glenister, 2019, PloS one.

Platinum drug distribution in cancer cells and tumors.

T. Hambley, A. V. Klein, 2009, Chemical reviews.

Effects of enzymatic activation on the distribution of fluorescently tagged MMP-2 cleavable peptides in cancer cells and spheroids.

Nicole S. Bryce, T. Hambley, N. Metzler‐Nolte, 2012, Bioconjugate chemistry.

Synthesis and characterization of complexes of thiomolybdates and thiotungstates with copper(I) and silver(I) cyanides, including molybdenum-95 and tungsten-183 NMR properties and the crystal and molecular structures of (n-Pr4N)2[(CN)CuS2MoS2], (n-Pr4N)2[(CN)AgS2WS2], and (Ph4As)2[(CN)CuS2MoS2Cu(CN)

M. R. Snow, J. Rodgers, T. Hambley, 1984 .

Rhodium complexes containing bidentate imidazolyl ligands : synthesis and structure

T. Hambley, L. Field, P. Turner, 1999 .

Cobalt complexes with tripodal ligands: implications for the design of drug chaperones.

T. Hambley, J. Clegg, R. Hocking, 2012, Dalton transactions.

Macrocyclic ligand design. X-Ray, DFT and solution studies of the effect of N-methylation and N-benzylation of 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane on its affinity for selected transition and post-transition metal ions

J. Reimers, L. Lindoy, T. Hambley, 2001 .

Novel polyamide amidine anthraquinone platinum(II) complexes: cytotoxicity, cellular accumulation, and fluorescence distributions in 2D and 3D cell culture models

Nicole S. Bryce, T. Hambley, A. V. Klein, 2021, JBIC Journal of Biological Inorganic Chemistry.

Dual targeting of hypoxic and acidic tumor environments with a cobalt(III) chaperone complex.

Nicole S. Bryce, T. Hambley, A. Renfrew, 2012, Journal of medicinal chemistry.

Getting to the core of platinum drug bio-distributions: the penetration of anti-cancer platinum complexes into spheroid tumour models.

Nicole S. Bryce, M. D. de Jonge, D. Howard, 2012, Metallomics : integrated biometal science.

Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: the effect of charge on drug distribution in solid tumour models.

Nicole S. Bryce, R. Whan, T. Hambley, 2009, Chemical communications.

A ratiometric fluorescent sensor for the mitochondrial copper pool.

T. Hambley, Jacek L Kolanowski, E. New, 2016, Metallomics : integrated biometal science.

Platinum(IV) antitumour compounds: their bioinorganic chemistry

M. Hall, T. Hambley, 2002 .

Platinum Anticancer Drugs, Chemical Biology of

R. Whan, T. Hambley, Jenny Z. Zhang, 2008 .

Intracellular trafficking as a determinant of AS-DACA cytotoxicity in rhabdomyosarcoma cells

Nicole S. Bryce, B. Stewart, T. Hambley, 2011, BMC Cell Biology.

The influence of the ancillary ligand on the potential of cobalt(iii) complexes to act as chaperones for hydroxamic acid-based drugs.

T. Hambley, P. Turner, A. Renfrew, 2017, Dalton transactions.

The Crystal Structure of (2,2′-Bipyridine)(pyrazine)(2,2′:6′,2″-terpyridine)ruthenium(II) Hexafluorophosphate

P. A. Lay, T. Hambley, P. Gulyás, 1996 .

The effect of charge on the uptake and resistance to reduction of platinum(IV) complexes in human serum and whole blood models.

T. Hambley, P. Kappen, A. Renfrew, 2020, Metallomics : integrated biometal science.

Pt(IV) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate.

T. Hambley, E. Wexselblatt, D. Gibson, 2012, Chemical communications.

Basis for design and development of platinum(IV) anticancer complexes.

M. Hall, T. Hambley, R. Callaghan, 2007, Journal of medicinal chemistry.

Modifying the properties of platinum (IV) complexes in order to increase biological effectiveness.

T. Hambley, G. Deacon, G. Fallon, 1999, Journal of inorganic biochemistry.

Cycloxazoline: A cytotoxic cyclic hexapeptide from the ascidian lissoclinum bistratum

T. Hambley, M. Lavin, C. Hawkins, 1992 .

Systematic differences in electrochemical reduction of the structurally characterized anti-cancer platinum(IV) complexes [Pt{((p-HC6F4)NCH2)2}-(pyridine)2Cl2], [Pt{((p-HC6F4)NCH2)2}(pyridine)2(OH)2], and [Pt{((p-HC6F4)NCH2)2}(pyridine)2(OH)Cl].

A. Bond, T. Hambley, G. Deacon, 2012, Journal of inorganic biochemistry.

The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity.

T. Hambley, A. Carnero, A. Quiroga, 2011, Dalton Transactions.

The interaction of metal ions and Marimastat with matrix metalloproteinase 9.

T. Hambley, C. Underwood, J. G. Lyons, 2003, Journal of inorganic biochemistry.

Growth of DLD-1 Colon Cancer Cells on Variotis™ Scaffolds of Controlled Porosity: A Preliminary Study

Nicole S. Bryce, A. Ruys, R. Whan, 2010 .

Spin-Orbit Mixing and Nephelauxetic Effects in the Electronic Spectra of Nickel(II)-Encapsulating Complexes Involving Nitrogen and Sulfur Donors.

T. Hambley, L. Gahan, R. Stranger, 1997, Inorganic chemistry.

A Novel Potassium-Binding Hydrolysis Product of Ascidiacyclamide: A Cyclic Octapeptide Isolated from the Ascidian Lissoclinum patella.

T. Hambley, D. Fairlie, L. Gahan, 1996, Inorganic chemistry.

Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin.

T. Hambley, T. Friedrich, E. New, 2014, Metallomics : integrated biometal science.

Factors affecting the assembly of helical and non-helical zinc(II) bipyridyl metallomacrocycles

T. Hambley, A. Bilyk, P. Turner, 1994 .

Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.

W. Hunter, T. Hambley, G. Leonard, 1993, Acta crystallographica. Section D, Biological crystallography.

The influence of structure on the activity and toxicity of Pt anti-cancer drugs

T. Hambley, 1997 .

3-Amino-6,6′-bis(methoxycarbonyl)-2,2′-bipyridine, a model for the central chelation unit of streptonigrin

T. Hambley, M. Harding, G. Long, 1995 .

Synthesis, properties and complexation studies on 3-amino-6,6′-dimethyl-2,2′-bipyridine

T. Hambley, M. Harding, G. Long, 1993 .

Metallocycle synthesis accelerated by high pressure

A. George, T. Hambley, L. Field, 1997 .

Supramolecular self-assembly of a toroidal inclusion complex, [NH4][Co8(MeCO2)8(OMe)16][PF6]

T. Hambley, J. Beattie, John A. Klepetko, 1998 .

XANES determination of the platinum oxidation state distribution in cancer cells treated with platinum(IV) anticancer agents.

M. Hall, P. Beale, T. Hambley, 2003, Journal of the American Chemical Society.

Stabilization of cobalt(I) by the tripodal ligandstris(2-pyridyl)methane and tris(2-pyridyl)phosphine. Structural,spectroscopic and ab initio studies of the[CoL2]n+ species

P. A. Anderson, J. Gulbis, E. Tiekink, 1997 .

Polypyrazolylmethane complexes of ruthenium

T. Hambley, L. Field, B. Messerle, 2001 .

Copper(II) complexes of the fluoroquinolone antimicrobial ciprofloxacin. Synthesis, X-ray structural characterization, and potentiometric study.

T. Hambley, L. Gahan, B. Charles, 1996, Journal of inorganic biochemistry.

Synthesis, X-ray Structural Determination, and Magnetic Susceptibility, Mössbauer, and EPR Studies of (Ph4P)2[Fe2(Cat)4(H2O)2]·6H2O, a Catecholato-Bridged Dimer of Iron(III)

T. Hambley, C. Hawkins, L. Gahan, 1996 .

Photochemical reactions of [cis-Fe(H)2(Me2PCH2CH2PMe2)2] with thiophenes: insertion into C–H and C–S bonds

T. Hambley, L. Field, A. Mcqueen, 1994 .

Investigations using fluorescent ligands to monitor platinum(IV) reduction and platinum(II) reactions in cancer cells.

T. Hambley, Jenny Z. Zhang, E. New, 2009, Dalton transactions.

Redox properties of potassium μ-thio-bis(hexacyanomolybdate(IV)

T. Hambley, G. Lawrance, N. C. Howlader, 1983 .

Element 78 – Platinum

T. Hambley, 2019, Australian Journal of Chemistry.

Interactions of cisplatin and the copper transporter CTR1 in human colon cancer cells

T. Hambley, E. New, M. C. Åkerfeldt, 2017, JBIC Journal of Biological Inorganic Chemistry.

Structural and anticancer properties of hydrogen bonded diphenyl phosphate adducts of Pt(IV) complexes: the importance of pKa matching.

T. Hambley, G. Deacon, T. Failes, 2012, Journal of inorganic biochemistry.

Stabilization of Triam(m)inechloridoplatinum Complexes by Oxidation to PtIV

M. Hall, T. Hambley, T. Failes, 2011 .

Enantioselectivity and stereoselectivity in the reactions of the enantiomers of the platinum complex [PtCl2(ahaz)] (ahaz=3(R)- or 3(S)-aminohexahydroazepine) with DNA.

T. Hambley, H. Er, 2009, Journal of inorganic biochemistry.

Binding of [Pt(1C3)(dien)](2+) to the duplex DNA oligonucleotide 5'-d(TGGCCA)-3': the effect of an appended positive charge on the orientation and location of anthraquinone intercalation.

R. Whan, T. Hambley, B. Messerle, 2009, Dalton Transactions.

A ratiometric iron probe enables investigation of iron distribution within tumour spheroids.

T. Hambley, Jacek L Kolanowski, E. New, 2018, Metallomics : integrated biometal science.

Synthesis, characterisation and in vitro cytotoxicity studies of a series of chiral platinum(II) complexes based on the 2-aminomethylpyrrolidine ligand: X-ray crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr=N-dimethyl-2(R)-aminomethylpyrrolidine).

P. Beale, T. Hambley, C. Diakos, 2009, European journal of medicinal chemistry.

The resolution of 5,5,7-trimethyl-1,4-diazacycloheptane: coordination to platinum(II), crystal structure of the dichloroplatinum(II) complex and HPLC separation of the [Pt(GpG)(tmdz)] adducts

T. Hambley, R. R. Fenton, Vivienne P. Munk, 1999 .

Basis for Design and Development of Platinum(IV) Anticancer Complexes

M. Hall, T. Hambley, R. Callaghan, 2007 .

Reactions of transition-metal .sigma.-acetylide complexes. 1. The reaction between W(C2Ph)(CO)3(.eta.-C5H5) and tetracyanoethylene: x-ray structure of W(CO)2[.eta.3-C(CN)CPhC:C(CN)2](.eta.-C5H5).cntdot.0.5C2(CN)4

M. R. Snow, T. Hambley, M. Bruce, 1985 .

Synthesis and characterization of Rh(P(CH3)3)2(CO)CH3 and Rh(P(CH3)3)2(CO)Ph

T. Hambley, L. Field, M. Partridge, 1993 .

Structural insights into transition-metal carbonyl bonding

T. Hambley, R. Hocking, 2003 .

The crystal structure of R,S,R,S-(1,4,8,11-tetramethyl-1,4,8,11-tetraazacyclotetradecane)nickel(II) bis(trifluoromethanesulphonate)–acetone hydrate, [Ni(tmtactd)][CF3SO3]2·Me2CO·H2O, and a strain-energy minimization analysis of four-, five-, and six-co-ordinate nickel(II)–tmtactd solvento complexes

T. Hambley, 1986 .

XANES investigation of the Co oxidation state in solution and in cancer cells treated with Co(III) complexes.

M. Hall, P. Beale, T. Hambley, 2006, Journal of inorganic biochemistry.

Synthesis, spectroscopy, and theoretical studies of platinum(II) phosphate complexes

J. Platts, T. Hambley, G. Deacon, 2002 .

DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins.

T. Hambley, V. Brabec, M. Vojtíṥková, 2005, Biochemical and biophysical research communications.

6.5 – Platinum

T. Hambley, L. Rendina, 2003 .

DFT study of the systematic variations in metal-ligand bond lengths of coordination complexes: the crucial role of the condensed phase.

T. Hambley, R. Hocking, R. Deeth, 2007, Inorganic chemistry.

Syntheses and structures of N-polyfluorophenyl- and N,N′-bis(polyfluorophenyl)ethane-1,2-diaminato(1- or 2-)platinum(II) complexes

A. Bond, T. Hambley, G. Deacon, 2010 .

Synthesis, Structure, Biological Activity, and DNA Binding of Platinum(II) Complexes of the Type trans-[PtCl(2)(NH(3))L] (L = Planar Nitrogen Base). Effect of L and Cis/Trans Isomerism on Sequence Specificity and Unwinding Properties Observed in Globally Platinated DNA.

T. Hambley, N. Farrell, H. L. Nguyen, 1999, Inorganic chemistry.

Preparation of stable, camphor-derived, optically active allyl and alkyl sulfoxides and thermal epimerization of the allyl sulfoxides

T. Hambley, R. Haynes, D. Ridley, 1988 .

Organolanthanoids V. The crystal and molecular structure of DI-η5-cyclopentadienyl-1,2-dimethoxyethaneytterbium(II)

T. Hambley, G. Deacon, John C. Taylor, 1983 .

Metal-Based Therapeutics

Trevor W. Hambley, T. Hambley, 2007, Science.

Copper complexes of non-steroidal anti-inflammatory drugs: an opportunity yet to be realized

P. A. Lay, N. Davies, T. Hambley, 2002 .

13C N.M.R. and Single-Crystal X-Ray Structural Investigation of the Fluoroquinolone Antimicrobial Drug Norfloxacin 2DCl.D2O

T. Hambley, L. Gahan, B. Charles, 1994 .

NMR spectroscopic characterization of copper(II) and zinc(II) complexes of indomethacin.

Saadallah Ramadan, P. A. Lay, T. Hambley, 2004, Inorganic chemistry.

Preparation and characterization of dinuclear copper–indomethacin anti-inflammatory drugs

P. A. Lay, T. Hambley, B. Kennedy, 2001 .

Trisimidazole complexes of ruthenium and osmium

T. Hambley, L. Field, B. Messerle, 1997 .

Interpretation of Electronic and EPR Spectra of Copper(II) Amine Complexes: A Test of the MM-AOM Method

Peter Comba, Trevor W. Hambley, P. Comba, 1995 .

Sexidentate co-ordination of the pendant-arm macrocycle 6,13-dimethyl-1,4,8,11-tetraazacyclotetradecane-6,13-diamine (L1) to zinc(II). Crystal structure of [ZnL1][ClO4]2·H2O

M. Maeder, T. Hambley, G. Lawrance, 1991 .

Encapsulated metal ions: synthesis, structure, and spectra of nitrogen-sulfur ligand atom cages containing cobalt(III) and cobalt(II)

M. R. Snow, T. Hambley, L. Gahan, 1982 .

Anti-Inflammatory Dinuclear Copper(II) Complexes with Indomethacin. Synthesis, Magnetism and EPR Spectroscopy. Crystal Structure of the N,N-Dimethylformamide Adduct.

P. A. Lay, T. Hambley, B. Kennedy, 1999, Inorganic chemistry.

Three chromium(III) complexes with dipeptide ligands

W. Hunter, T. Hambley, M. Cooper, 1986 .

Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper–indomethacin in rats

P. A. Lay, N. Davies, T. Hambley, 2010, Cancer Chemotherapy and Pharmacology.

Diamagnetic .dblarw. paramagnetic equilibria in solutions of bis(dialkylphosphino)ethane complexes of iron

T. Hambley, L. Field, M. Baker, 1988 .

Gastrointestinal toxicity, antiinflammatory activity, and superoxide dismutase activity of copper and zinc complexes of the antiinflammatory drug indomethacin.

P. A. Lay, N. Davies, T. Hambley, 2003, Chemical research in toxicology.

Synthesis, structure and magnetism of iron-( III ) and -( II ) complexes of 1-thia-4,7-diazacyclononane and N,N′-dimethyl-1-thia-4,7-diazacyclononane

T. Hambley, L. Gahan, G. Hanson, 1997 .

Copper(II) bipyridyl and iminopyridyl analogoues of streptonigrin

T. Hambley, P. Turner, M. Harding, 1995 .

MODELS OF THE ACTIVE SITE OF DIHYDROOROTASE : STRUCTURE OF DIAQUABIS(L-DIHYDROOROTATO)ZINC(II) REVEALS AN UNEXPECTED COORDINATION MODE FOR THE L-DIHYD ROOROTATO LIGANDS

R. Christopherson, T. Hambley, E. S. Zvargulis, 1995 .

Synthesis and crystal structure of a vanadium(V) complex with a 2-hydroxy acid ligand, (NH4)2[V(OC(CH2CH3)2COO)(O)2]2: a structural model of both vanadium(V) transferrin and ribonuclease complexes with inhibitors

P. A. Lay, T. Hambley, R. Judd, 1992 .

Reactions of transition-metal .sigma.-acetylide complexes. 2. Cycloaddition and subsequent reactions of tetracyanoethylene with some (.eta.-cyclopentadienyl)ruthenium-tertiary phosphine complexes: x-ray structure of Ru{C[:C(CN)2]CPh:C(CN)2}(dppe)(.eta.-C5H5).cntdot.0.5CHCl3

M. R. Snow, T. Hambley, M. Bruce, 1985 .

Cobalt(III) Chaperone Complexes of Curcumin: Photoreduction, Cellular Accumulation and Light-Selective Toxicity towards Tumour Cells.

Nicole S. Bryce, T. Hambley, A. Renfrew, 2015, Chemistry.

Effect of guest molecules, metal ions and linker length on the assemblyof chiral [2 + 2] metallomacrocycles: solutionstudies and crystal structures

T. Hambley, A. Bilyk, P. Turner, 1997 .

Targeting curcumin to specific tumour cell environments: the influence of ancillary ligands.

D. Paterson, T. Hambley, A. Renfrew, 2017, Metallomics : integrated biometal science.

Delivery and release of curcumin by a hypoxia-activated cobalt chaperone: a XANES and FLIM study

Nicole S. Bryce, T. Hambley, A. Renfrew, 2013 .

Structural measures of element-oxygen bond covalency from the changes to the delocalisation of the carboxylate ligand.

T. Hambley, R. Hocking, Trevor W Hambley, 2005, Dalton transactions.

Crystal structure of Iodobis(1,10-phenanthroline)copper(II) iodide octasulphur

T. Hambley, C. Raston, A. White, 1977 .

Sulphur chromium complexes: syntheses and crystal structures of (η5C5H5)2Cr2(CO)4S and (η5-C5H5)2Cr2(CO)5S2

T. Hambley, G. B. Robertson, L. Goh, 1983 .

Structure and dynamics of a platinum(II) aminophosphine complex and its nucleobase adducts

P. Sadler, T. Hambley, N. Margiotta, 2001 .

The mechanism of action of platinum(IV) complexes in ovarian cancer cell lines.

M. Hall, P. Beale, T. Hambley, 2004, Journal of inorganic biochemistry.

cis-[PtCl2(NH3){2-(2-hydroxyethyl)pyridine}] − an Analogue of the Anticancer Drug AMD473: Unusual Hydrolysis Rates and pKa Values for the Diaqua Adduct

P. Sadler, T. Hambley, J. Parkinson, 2002 .

Water-Soluble α-Amino Acid Complexes of Molybdenum as Potential Antidotes for Cyanide Poisoning: Synthesis and Catalytic Studies of Threonine, Methionine, Serine, and Leucine Complexes.

T. Hambley, W. Lewis, S. Jonsdottir, 2020, Inorganic chemistry.

Kinetics and structural aspects of the cisplatin interactions with guanine: A quantum mechanical description

T. Hambley, W. Rocha, W. B. Almeida, 2006 .

APPLICATIONS OF MOLYBDENUM-95 NMR SPECTROSCOPY. 7. STUDIES OF METAL-METAL BONDED SYSTEMS INCLUDING AQUEOUS MOLYBDENUM(IV) AND MOLYBDENUM(V). CRYSTAL AND MOLECULAR STRUCTURE OF NA2(MO3O4((O2CCH2)2NCH3)3).7H2O

T. Hambley, R. Brownlee, A. G. Wedd, 1983 .

Variable deprotonation of an aromatic amino ligand by molybdenum(VI). Crystal and molecular structure of mer-Bis[2,2'-{1,2-phenylenebis(iminomethylene)}-bis(phenol)ato(3–)]molybdenum(VI)

T. Hambley, A. G. Wedd, K. Murray, 1984 .

Synthesis, structure, and spectroscopy of encapsulated complexes of cobalt(III) derived from the ligand 5-methyl-5-(4-amino-2-thiabutyl)-3,7-diazanonane-1,9-diamine (N5S)

T. Hambley, L. Gahan, R. Stranger, 1993 .

Synthesis, x-ray crystal structure, and metal ion extraction from a nitrogen-sulfur "pendant arm" encapsulated complex of cobalt(III)

T. Hambley, L. Gahan, T. M. Donlevy, 1990 .

XAFS studies of anti-inflammatory dinuclear and mononuclear Zn(II) complexes of indomethacin.

P. A. Lay, T. Hambley, B. Kennedy, 2003, Inorganic chemistry.

Metal ion encapsulation: cobalt cages derived from polyamines, formaldehyde, and nitromethane

M. R. Snow, T. Hambley, J. Harrowfield, 1984 .

Metal ion encapsulation: cobalt cages derived from polyamines, formaldehyde, and nitromethane

M. R. Snow, T. Hambley, J. Harrowfield, 1984 .

Developing new metal-based therapeutics: challenges and opportunities.

T. Hambley, 2007, Dalton transactions.

Structure and Spectroscopy of the Copper(II) Complex of the Unsymmetric Encapsulating Ligand 1-Methyl-8-ammonio-3,13-dithia-6,10,16,19-tetraazabicyclo[6.6.6]icosane (AMN4S2sar)

T. Hambley, L. Gahan, G. Hanson, 1994 .

Synthetic, structural, and physical studies of tris(2,4-pentanedionato)vanadium(IV) hexachloroantimonate(V) and tris(1-phenyl-1,3-butanedionato)vanadium(IV) hexachloroantimonate(V)

T. Hambley, C. Hawkins, T. Kabanos, 1987 .

Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies

T. Hambley, J. Blay, Robert A. Gossage, 2011 .

Synthesis and structures of copper(II) and nickel(II) complexes of 1,8-diaza-4-thiaoctane. Characterization of a novel polymeric trigonal bipyramidal copper(II) complex containing both bridging and meridionally coordinated ligands

T. Hambley, L. Gahan, 1988 .

Statistical and molecular mechanics analysis of the effects of changing donor type on bond length in the two series [Co(III)N(n)O(6-n)] and [Ni(II)N(n)O(6-n)] (n = 0-6): a new route to bond-stretch Parameters.

T. Hambley, R. Hocking, 2002, Inorganic chemistry.

The preparation of mixed ligand ruthenocenes containing bulky cyclopentadienyl ligands. Crystal structures of pentaphenylruthenocene, [Ru(η5-C5Ph5)(η5-C5H5)], pentaparatolylruthenocene, [Ru{η5-C5(p-MeC6H4)5}(η5-C5H5)] and pentaphenylpentamethylruthenocene, [Ru(η5-C5Ph5)(η5-C5Me5)]

T. Hambley, A. Masters, L. Field, 1998 .

The preparation, crystal structure and some reaction chemistry of Bromo (η5-penta- phenylcyclopentadienyl) dicarbonylosmium (II) , [Os (η5-C5Ph5) (CO) 2Br]

T. Hambley, A. Masters, L. Field, 1998 .

Stereochemical Study of a 13β,28-Epoxyoleanane

T. Hambley, D. Tucker, P. Turner, 1998 .

Syntheses and Comparative Base Hydrolysis Reactions of Chlorocobalt(III) Complexes of Pendant-Arm Macrocyclic Polyamines and Polyamino Acids

T. Hambley, G. Lawrance, Yakup Baran, 1997 .

A Saturated Heterocycle Formed from Ethane-1,2-diamine, Formaldehyde and Nitroethane: Crystal Structure of 6-Methyl-6-nitro-1,4-bis(2′-nitropropan-1′-yl)-1,4-diazacycloheptane

M. Maeder, T. Hambley, G. Lawrance, 1997 .

Dinuclear Platinum Complexes Form a Novel Intrastrand Adduct with d(GpG), an anti−syn Conformation of the Macrochelate As Observed by NMR and Molecular Modeling

T. Hambley, N. Farrell, Y. Qu, 1996 .

SYNTHESIS OF NOVEL RUTHENIUM COMPLEXES CONTAINING BIDENTATE IMIDAZOLE-BASED LIGANDS

T. Hambley, L. Field, P. Turner, 1997 .

Isolation and complexation of the cis isomer of the pendant arm macrocycle 6,13-dimethyl-1,4,8,11-tetraazacyclotetradecane-6,13-diamine

P. Comba, T. Hambley, G. Lawrance, 1992 .

Coordination of the "pendant-arm" macrocycle 6,13-diamino-6,13-dimethyl-1,4,8,11-tetraazacyclotetradecane to chromium(III). Crystal structure and physical properties of the hexacoordinated complex ion

M. Maeder, P. Comba, T. Hambley, 1990 .

Crystal Structures of [H4L](ClO4)4.6H2O And [Zn(H2L)(S2O6)2].4H2O (L = 6,13-Dimethyl-1,4,8,11-tetraazacyclotetradecane-6,13-diamine)

T. Hambley, G. Lawrance, P. Bernhardt, 1990 .

6, 13-Diamino-6,13-dimethyl-1,4,8,11-tetra-azacyclotetradecane, L7, a new, potentially sexidentate polyamine ligand. Variable co-ordination to cobalt (III) and crystal structure of the complex[CO(L7)]Cl2[ClO4]

T. Hambley, G. Lawrance, P. Bernhardt, 1989 .

Co-ordination of 6,13-diamino-6,13-dimethyl-1,4,8,11-tetra-azacyclotetradecane to iron(III). The first fully characterised hexa-amineiron(III) complex

T. Hambley, G. Lawrance, P. Bernhardt, 1989 .

Hexaco-ordination of a diamino-substituted tetra-azameacrocycle to cobalt(III) and nickel(II): compressed Co–N bonds?

T. Hambley, G. Lawrance, G. Gainsford, 1987 .

Copper and zinc complexes as antiinflammatory drugs.

P. A. Lay, T. Hambley, B. Kennedy, 2004, Metal ions in biological systems.

Models of the active sites of zinc-containing enzymes: the structure of acetato[hydrotris(3-tert-butyl-5-methylpyrazol-1-yl)borato]zinc(II)

T. Hambley, M. Lynch, E. S. Zvargulis, 1996 .

MODELS OF THE ACTIVE SITES OF ZINC CONTAINING ENZYMES : THE CRYSTAL STRUCTURES OF TWO BIS(TRIPOD)ZINC(II) COMPLEXES

T. Hambley, Irmi E. Buys, E. S. Zvargulis, 1995 .

The stereospecific synthesis of Lambda-alpha-{dipyrido[3,2-a:2'3'-c](6,7,8,9-tetrahydro)phenazine[N,N'-di(2-picolyl)-2,5-dimethyl-2S,5S-diaminocyclohexane]ruthenium(II)} and related beta isomers

Peter A. Williams, T. Hambley, J. Aldrich-Wright, 2002 .

Minor groove intercalation of Δ-[Ru(Me2phen)2dppz]2+ to the hexanucleotide d(GTCGAC)2

J. Collins, T. Hambley, J. Aldrich-Wright, 2002 .

A 1H NMR Study of the DNA Binding of Ruthenium(II) Polypyridyl Complexes

J. Collins, T. Hambley, J. Aldrich-Wright, 1998 .

Mercury(II) and Lead(II) Complexes of 1-Oxa-7-thia-4,10-diazacyclododecane ([12]aneN2OS)

T. Hambley, L. Gahan, S. Afshar, 1999 .

Metal-directed syntheses of dithiadiazacyclotetradecane macrocycles with pendant alcohol and nitro or carboxylate groups involving macrocycle ring expansion

M. Maeder, T. Hambley, G. Lawrance, 1995 .

CHIRAL QUADRIDENTATE LIGANDS BASED ON AMINO-ACIDS - TEMPLATE SYNTHESES AND PROPERTIES OF THE FREE LIGANDS AND THEIR TRANSITION-METAL COMPLEXES

P. Comba, T. Hambley, K. Várnagy, 1993 .

Bis(acetylide) complexes of iron

A. George, T. Hambley, L. Field, 1991 .

Synthesis and structure of FeCl(C.tplbond.CPh)(DMPE)2

A. George, T. Hambley, L. Field, 1990 .

Synthesis and structure of dichlorodi-[1,2-bis(dimethylphosphino)ethane]iron(III) tetrachloroferrate(III), [Fe(DMPE)2Cl2]+[FeCl4]−

A. George, T. Hambley, L. Field, 1990 .

Template Synthesis, Crystal Structure, and Spectroscopic Characterization of [N,N′‐Bis(2‐pyridylmethylene)‐1,3‐diamino‐2‐methyl‐2‐nitropropane] copper(II) Perchlorate

P. Comba, T. Hambley, G. Lawrance, 1985 .

Iron(II) complexes containing poly(1-pyrazolyl)methane ligands

T. Hambley, L. Field, P. Turner, 2002 .

Synthesis, spectroscopy and structure of the cobalt(III) complex of the hexadentate ligand 5-(4-Amino-2-thiabutyl)-5-methyl-3, 7-dithianonane-1, 9-diamine

T. Hambley, L. Gahan, R. Stranger, 1993 .

Chlorocobalt(III) and chlorochromium(III) complexes of a new chiral quinquedentate polyamine based on RR-trans-cyclohexane-1,2-diamine

M. Maeder, T. Hambley, G. Lawrance, 1993 .

Synthesis and structural characterization of the bimetallic complex [Fe([9])aneS3)2][FeCl4·2H2O

T. Hambley, L. Gahan, G. Hanson, 1996 .

Iron(III) and iron(II) complexes of 1-thia-4,7-diazacyclononane ([9]aneN2S) and 1,4-dithia-7-azacyclononane ([9]aneNS2). X-Ray structural analyses, magnetic susceptibility, Mössbauer, EPR and electronic spectroscopy†

T. Hambley, L. Gahan, J. Cashion, 1998 .

Template syntheses of chiral tetradentate ligands derived from L-amino acids. Structural and spectroscopic characterization of the free ligands and of their copper(II) complexes

P. Comba, T. Hambley, G. Lawrance, 1991 .

Pendant arm encapsulated complexes

T. Hambley, L. Gahan, A. Achilleos, 1988 .

Structure and redox properties of the molybdenum(IV) metal cluster K5[Mo3S4(CN)9].7H2O

T. Hambley, G. Lawrance, N. Howlader, 1983 .

Synthesis and X-ray structural characterization of an iron(III) complex of the fluoroquinolone antimicrobial ciprofloxacin, [Fe(CIP)(NTA)]3·5H2O (NTANitrilotriacetato)

T. Hambley, L. Gahan, B. Charles, 1995 .

Butenynyl complexes of iron(II) containing the tripodal tetraphosphine ligand P(CH2CH2PMe2)3

T. Hambley, R. Smernik, L. Field, 1999 .

Iron Complexes Containing the Tripodal Tetraphosphine Ligand P(CH2CH2PMe2)3

T. Hambley, R. Smernik, L. Field, 1997 .

Structure of trans-Bis{3-methylbut-3-en-1-yn-1-yl}bis{1,2-bis(dimethylphosphino)ethane}iron(II)

A. George, T. Hambley, L. Field, 1997 .

A reductive rearrangement of iron acetylide hydride complexes

A. George, T. Hambley, L. Field, 1997 .

The Directionality of d‐Orbitals and Molecular‐Mechanics Calculations of Octahedral Transition‐Metal Compounds

Peter Comba, Trevor W. Hambley, Marc Ströhle, 1995 .

Determination of solution structures of binuclear copper(II) complexes

P. Comba, T. Hambley, P. Bernhardt, 1992 .

Preparations and Crystal-Structures of the 2-Oxides of Some Octahydro-3,2,1-Benzoxathiazines and Octahydro-2h-3,1,2-Benzoxazaphosphorines

T. Hambley, D. Ridley, R. Goodridge, 1986 .

The preparation of (R)- and (S)-(E)-but-2-enyl-t-butylphenylphosphine oxides and their enantiospecific conversion into enantiomeric hydrindenones related to vitamin D

T. Hambley, R. Haynes, J. P. Stokes, 1991 .

Metal-Directed Synthesis of Dithia Diaza Macrocycles Carrying Pendant Alcohol and Also Nitro or Carboxylate Groups

M. Maeder, T. Hambley, G. Lawrance, 1995 .

Synthesis of a new potentially sexidentate pendant-arm macrocyclic polyamino acid and co-ordination to cobalt(III)

M. Maeder, T. Hambley, G. Lawrance, 1992 .

Helical Figure-of-Eight Loop Dicopper(I) Compounds: Syntheses, Structures, and Dynamics.

P. Comba, T. Hambley, D. Richens, 1998, Inorganic chemistry.

Double Helical Dinuclear Copper(I) Complexes of Macrocyclic Bis(dithiadiimine) Ligands

P. Comba, T. Hambley, D. Richens, 1995 .

The isolation and crystal structure of the powerful Lewis acid, planar tetrakispyridine cobalt(II), [Co(C5H5N)4]2+, as its mixed chloride hexafluorophosphate salt

T. Hambley, A. Masters, J. Beattie, 1996 .

Copper(I) complexes of dinucleating macrocyclic bis(dithiadiimine) ligands

T. Hambley, G. Lawrance, P. Turner, 1998 .

Octahedral non-helical bis(bipyridyl) metallomacrocycles

T. Hambley, A. Bilyk, P. Turner, 1995 .

Investigations into the interactions between DNA and conformationally constrained pyridylamineplatinum(II) analogues of AMD473.

T. Hambley, L. T. Ellis, B. Messerle, 2003, Inorganic chemistry.

Three chromium(III) complexes with mixed amino acid ligands: (l‐cysteinato)(l‐histidinato)chromium(III) 3.5‐hydrate, (l‐aspartato)(l‐histidinato)chromium(III) 1.5‐hydrate and bis(dl‐histidinato)chromium(III) chloride 4.2‐hydrate

T. Hambley, W. R. Tulip, M. Cooper, 1990 .

Synthesis and single-crystal x-ray study of the mononuclear dihapto-benzyne (dehydrobenzene) nickel(0) complex Ni(.eta.2-C6H4)[(C6H11)2PCH2CH2P(C6H11)2]. Insertion reactions with simple molecules and x-ray crystal structure of the nickelaindan complex Ni(CH2CH2C6H4-o)[(C6H11)2PCH2CH2P(C6H11)2]

T. Hambley, M. A. Bennett, G. B. Robertson, 1985 .

A new synthesis, resolution and in vitro activities of (R)- and (S)-β-phenyl-GABA

T. Hambley, R. Allan, G. Johnston, 1990 .

Aprotic conjugate addition of allyllithium reagents bearing polar groups to cyclic enones. 2. 2-Alkyl-, 2,3-dialkyl- and 1,3-dialkylallyl systems

T. Hambley, A. Katsifis, R. Haynes, 1988 .

Synthesis and characterisation of nitrile complexes of iron

A. George, T. Hambley, B. Skelton, 1997 .

Cellular uptake and distribution of cobalt complexes of fluorescent ligands

Trevor W. Hambley, Paul D. Bonnitcha, T. Hambley, 2008, JBIC Journal of Biological Inorganic Chemistry.

Hydrogenolysis of a pendant alcohol dithiadiazamacrocycle. Crystal structure of the 6-amino-6-methyl-1, 11-dithia-4,8-diazacyclotetradecane hydrogenolysis product as a chlorocobalt(III) complex

M. Maeder, T. Hambley, G. Lawrance, 1997 .

Synthesis and spectroscopic properties of the encapsulated cobalt(III) complexes derived from the unsymmetrically substituted ligand 5-methyl-5-(4-amino-2-azabutyl)-3,7-dithianonane-1,9-diamine (N4S2)

T. Hambley, L. Gahan, R. Stranger, 1992 .

The isomers of the bis(1-thia-4,7-diazacyclononane)cobalt(III) ion: separation and characterization

T. Hambley, L. Gahan, M. Bjerrum, 1988 .

Nuclear magnetic resonance analysis of indomethacin-induced gastric ulcers.

P. A. Lay, T. Hambley, S. Ramadan, 2005, Chemical research in toxicology.

Hinckdentine-A : a novel alkaloid from the marine bryozoan Hincksinoflustra denticulata

T. Hambley, W. C. Taylor, K. Picker, 1987 .

DNA-binding and molecular mechanics modelling studies of the bulky chiral platinum(II) complex [PtCl(2)(mepyrr)] (mepyrr=N-methyl-2-aminomethylpyrrolidine).

T. Hambley, C. Diakos, R. Fenton, 2006, Journal of inorganic biochemistry.

The influence of tumour microenvironmental factors on the efficacy of cisplatin and novel platinum(IV) complexes.

M. Hall, T. Hambley, M. Jaffar, 2005, Biochemical pharmacology.

Synthesis of a new P2N2 ligand N,N′-bis[2-(diphenylphosphino)phenyl]propane-1,3-diamine, H2L2, and some of its complexes with elements of the nickel triad and rhodium: X-ray structure analyses of the neutral complex [NiL2] and the trans-spanned [Rh(CO)Cl(H2L2)]

K. Henrick, T. Hambley, M. Mcpartlin, 1989 .

Cationic Iridium(I) Complexes as Catalysts for the Alcoholysis of Silanes

T. Hambley, L. Field, B. Messerle, 2003 .

Synthesis and reactions of azido complexes of iron

A. George, T. Hambley, L. Field, 1995 .

Preparation and X-ray crystal structure of Fe(Me2PCH2CH2CH2CH2PMe2)2Cl2

N. Bampos, T. Hambley, L. Field, 1992 .

Diamagnetic ⇄ Paramagnetic Equilibria in Solutions of Bis(dialkylphosphino)ethane Complexes of Iron.

T. Hambley, L. Field, M. Baker, 1988 .

Models of hypoxia activated prodrugs: Co(III) complexes of hydroxamic acids.

T. Hambley, T. Failes, 2006, Dalton transactions.

The antiplasmid action of some palladium(II) complexes of phenothiazine based pharmaceuticals and the crystal structure of protonated trichloro[10-(3′-dimethylaminopropyl) phenothiazine-S]-palladium(II)

T. Hambley, J. Molnár, A. Hevér, 1996 .

The Discovery and Development of Cisplatin

M. Hall, T. Hambley, R. Alderden, 2006 .

Steric contributions to the thermodynamics of electron transfer in cobalt(III) hexaamine complexes

T. Hambley, 1988 .

Isomers of 1,4,8,11-tetraazacyclotetradecane-6,13-dicarboxylate characterized as cobalt(III) complexes

M. Maeder, T. Hambley, G. Lawrance, 2003 .

Structural and strain‐energy‐minimization study of the geometric and configurational isomers of bis(l‐methioninato)cobalt(III)

T. Hambley, 1988 .

A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo

P. A. Lay, P. Barter, T. Hambley, 2016, Cell & Bioscience.

SYNTHESIS AND SOME OCTAHEDRAL COMPLEXES OF A CHIRAL TRIAZA MACROCYCLE

M. Maeder, T. Hambley, G. Lawrance, 1999 .

Database Analysis of Transition Metal Carbonyl Bond Lengths: Insight into the Periodicity of π Back-Bonding, σ Donation, and the Factors Affecting the Electronic Structure of the TM−C⋮O Moiety

T. Hambley, R. Hocking, 2007 .

The synthesis and characterization of norbornylsilasesquioxanes

T. Hambley, T. Maschmeyer, A. Masters, 1992 .

Modulating the Cellular Uptake of Fluorescently Tagged Substrates of Prostate-Specific Antigen before and after Enzymatic Activation.

Nicole S. Bryce, T. Hambley, Jenny Z. Zhang, 2018, Bioconjugate chemistry.

The synthesis of 2-cyclohexylideneperhydro-4,7-methanoindenes. Non-steroidal analogues of steroidal GABAA receptor modulators

T. Hambley, R. Allan, G. Johnston, 1998 .

Comparisons of .pi.-bonding and hydrogen bonding in isomorphous compounds: [M(NH3)5Cl]Cl2 (M = Cr, Co, Rh, Ir, Ru, Os)

P. A. Lay, T. Hambley, 1986 .

Potassium tris(oxalato)ruthenate(III)

T. Hambley, J. Beattie, R. Binstead, 1989 .

Models of surface-confined metallocene derivatives

T. Hambley, T. Maschmeyer, A. Masters, 1994 .

Reactions between tetracyanoethylene and transition metal acetylides: Formation and cleavage of the cyclobutenyl ring in an authentic tetracyanocyclobutenylmetal complex, W[(CN)2](CO)3(η-C5H5)

M. R. Snow, J. Rodgers, T. Hambley, 1982 .

Synthesis and X-ray crystal structure of the cobalt(III) complex of 6-methyl-6-(4-amino-2-azabutyl)-1-thia-4-azacycloheptane (atac), cis-[(Co(atac)Cl2]ClO4·H2O

T. Hambley, L. Gahan, T. M. Donlevy, 1993 .

Visualising the hypoxia selectivity of cobalt(III) prodrugs

Nicole S. Bryce, T. Hambley, Byung J. Kim, 2011 .

Structural investigations of palladium(II) and platinum(II) complexes of salicylhydroxamic acid.

M. Hall, D. Hibbs, T. Hambley, 2002, Inorganic chemistry.

Electron Exchange Reactions and Redox and Magnetic Properties of the Cobalt(III) and Cobalt(II) Complexes of the Encapsulating Ligand 3,13-Dithia-6,10,16,19-tetraazabicyclo[6.6.6]icosane (N4S2sar). Crystal Structure of the Cobalt(II) Complex [Co(HN4S2sar)](ClO4)2

T. Hambley, L. Gahan, T. M. Donlevy, 1994 .

Chemistry of [{Cr(cp)(CO)3}2], (cp =η5-C5H5). Reaction with elemental P4. A high yield synthesis and crystal structures of [{Cr(cp)(CO)2}2(µ-η2-P2)] and [Cr(cp)(CO)2(η3-P3)]

T. Hambley, R. Wong, C. Chu, 1989 .

Reaction of [{Cr(cp)(CO)3}2](cp =η5-C5H5) with elemental phosphorus. Isolation of [Cr2(cp)2(P5)] as a thermolysis product and its X-ray crystal structure

T. Hambley, R. Wong, C. Chu, 1990 .

Structural measure of metal-ligand covalency from the bonding in carboxylate ligands.

T. Hambley, R. Hocking, 2003, Inorganic chemistry.

A New Class of Layered Microporous Materials: Crystal Structure of Disodium Pentakis(trimethylphenylammonium) Bis[tris(oxalato(2-))chromate(III)] Chloride Pentahydrate

P. A. Lay, T. Hambley, R. P. Farrell, 1995 .

Isolation of pentamethylcyclopentadienylchromium tricarbonyl dimer by two methods. X-Ray crystal structural study of two polymorphs

T. Hambley, D. Darensbourg, J. Reibenspies, 1990 .

Cluster chemistry : X. Preparation of 1,2-bis(diphenylphosphino)ethane derivatives of Ru3(CO)12: crystal and molecular structures of Ru3(CO)10(η-PH2PCH2CH2PPh2)

M. R. Snow, T. Hambley, B. K. Nicholson, 1982 .

Chemistry of [CpCr(CO)3]2. Synthesis of Cp2Cr2(CO)4S, Cp2Cr2(CO)4S2, and Cp2Cr2(CO)5S2. Crystal structure and reactivity of Cp2Cr2(CO)4S2 and Cp2Cr2(CO)5S2

T. Hambley, G. B. Robertson, L. Goh, 1987 .

Isolation of [CpCr(CO)3]2(μ-SnCl2) and CpCrCl2(THF) from the insertion-displacement of Se in Cp2Cr2(CO)4Se with SnCl2. Crystal structure of CpCrCl2(CH3CN) (Cp = η5-C5H5)

T. Hambley, L. Goh, 1990 .

The crystal and molecular structure of (η5-pentaphenylcyclopentadienyl) (η5-cyclopentadienyl)iron(II), 1,2,3,4,5-pentaphenylferrocene, [Fe(C5Ph5)(C5H5)]

P. A. Lay, T. Hambley, A. Masters, 1993 .

The crystal and molecular structure of bromo (η5-pentaphenylcyclopentadienyl)dicarbonyliron(II), Fe(C5Ph5)(CO)2Br

T. Hambley, A. Masters, L. Field, 1989 .

Fluorescent sensing of monofunctional platinum species.

T. Hambley, K. Charles, E. New, 2015, Chemical communications.

X-ray Crystallographic Study of the Complexes Cr(PCl3)(CO)5, W(PCl3)(CO)5, Cr(PBr3)(CO)5, W(PBr3)(CO)5 and Mo(PMe3)(CO)5: Insight into .pi.-Acceptance by Phosphorus

T. Hambley, M. Davies, M. Aroney, 1995 .

Conformational studies of EPh3M(CO)5 complexes (E P, As or Sb; M Cr, Mo or W)

T. Hambley, M. Davies, G. W. Allen, 1994 .

Porphyrin analogues of Tröger's base: Large chiral cavities with a bimetallic binding site

T. Hambley, M. Crossley, L. Mackay, 1995 .

Central to axial chirality transfer via double bond migration: asymmetric synthesis and determination of the absolute configuration of axially chiral 1-(3′-indenyl)naphthalenes

T. Hambley, P. Turner, R. W. Baker, 1996 .

Modification of Platinum(II) Antitumor Complexes with Sulfur Ligands. 1. Synthesis, Structure, and Spectroscopic Properties of Cationic Complexes of the Types [PtCl(diamine)(L)]NO3 and [{PtCl(diamine)}2(L-L)](NO3)2 (L = Monofunctional Thiourea Derivative; L-L = Bifunctional Thiourea Derivative)

T. Hambley, N. Farrell, U. Bierbach, 1998 .

A fluorescent probe for investigating metabolic stability of active transplatin analogues

T. Hambley, Jacek L Kolanowski, E. New, 2018 .

Preparation and cell growth inhibitory activity of [PtR(2)L(2)] (R=polyfluorophenyl, L(2)=diene, cyclohexane-1,2-diamine (chxn) or cis-(dimethyl sulfoxide)(2)) and the X-ray crystal structure of [Pt(C(6)F(5))(2)(cis-chxn)].

T. Hambley, G. Deacon, C. Cullinane, 2002, Journal of inorganic biochemistry.

Reactions of tetracyanoethylene with transition-metal acetylides: synthesis and structure of Rh(CCPh) [η2-C2(CN)4] (NCMe)(PPh3)2

M. R. Snow, T. Hambley, M. Bruce, 1982 .

Targeting Strategies for Metal‐Based Therapeutics

T. Hambley, J. Norman, 2011 .

Cluster chemistry. Part 20. Preparation, X-ray crystal structures, and some reactions of [Fe3(CO)11(CNBut)] and [Fe3(CO)9(µ3-η2-CNBut)]

T. Hambley, B. K. Nicholson, M. Bruce, 1983 .

van der Waals Radii of Pt(II) and Pd(II) in Molecular Mechanics Models and an Analysis of Their Relevance to the Description of Axial M.H(-C), M.H(-N), M.S, and M.M (M = Pd(II) or Pt(II)) Interactions.

T. Hambley, 1998, Inorganic chemistry.

Interconversions of nickel carbonyl cluster anions

T. Hambley, A. Masters, J. Beattie, 1993 .

Preparation and characterization of iron complexes of the penta-p-tolylcyclopentadienyl and o-tolyltetraphenylcyclopentadienyl ligands

T. Hambley, A. Masters, L. Field, 1993 .

Crystal and molecular structures of pentaphenylcyclopentadiene and of an isomer, 4,8-diphenyltribenzo[b,f,i]tricyclo[6.2.1.01.5]undecane, the product of a novel metal-assisted photoreaction

T. Hambley, A. Masters, L. Field, 1992 .

Synthesis and characterisation of pentaphenylcyclo-pentadienyliron arene sandwich complex cations [Fe(η5-C5Ph5)(arene)]+ and the X-ray crystal structure of the [Fe(η5-C5Ph5)(η6-C6H5Me)]+ cation

P. A. Lay, T. Hambley, A. Masters, 1991 .

X-ray crystal structure of (eta(5)-pentaphenylcyclopentadienyl)[1-(eta(5/6)-phenyl)-2,3,4,5-tetraphenylcyclopentadienyl]iron(II), [Fe(eta(5)-C(5)Ph(5))[(eta(5/6)-C(6)H(5))C(5)Ph(4)]], a linkage isomer of decaphenylferrocene.

T. Hambley, A. Masters, L. Field, 2002, Inorganic chemistry.

The Structures of the Decaphenylmetallocenium Cations of Chromium and Cobalt

T. Hambley, A. Masters, L. Field, 1997 .

The Syntheses of [M(C5Ph5)2]n+ (N=0,1) Complexes of Nickel, Iron and Chromium. The Structures of the Decaphenylmetallocenium Cations of Nickel and Iron

T. Hambley, A. Masters, L. Field, 1996 .

Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids.

J. Hanrahan, T. Hambley, R. Allan, 1990, Journal of medicinal chemistry.

Facile preparation of mono-, di- and mixed-carboxylato platinum(IV) complexes for versatile anticancer prodrug design.

T. Hambley, E. Wexselblatt, D. Gibson, 2013, Chemistry.

Platinum(IV) organometallics I. Syntheses of trans-di(carboxylato)ethane-1,2-diamine-cis-bis(pentafluoro-phenyl)platinum(IV) complexes and the X-ray crystal structure of the n-butanoato derivative

T. Hambley, G. Deacon, L. Webster, 1995 .

Bioreductive activation and drug chaperoning in cobalt pharmaceuticals.

M. Hall, T. Hambley, T. Failes, 2007, Dalton transactions.

Using XANES to Monitor the Oxidation State of Cobalt Complexes

M. Hall, T. Hambley, T. Failes, 2007 .

Towards bioreductively activated prodrugs: Fe(III) complexes of hydroxamic acids and the MMP inhibitor marimastat.

T. Hambley, T. Failes, 2007, Journal of inorganic biochemistry.

Influence of equatorial and axial carboxylato ligands on the kinetic inertness of platinum(IV) complexes in the presence of ascorbate and cysteine and within DLD-1 cancer cells.

T. Hambley, Jenny Z. Zhang, J. Aitken, 2013, Journal of medicinal chemistry.

Tetraammonium hexahydrogenhexamolybdozincate(II) hexahydrate

T. Hambley, G. Lawrance, P. Turner, 1997 .

Crystal structures of [W(CO)5(PPh3)], [M(CO)5(AsPh3)] and [M(CO)5(SbPh3)](M = Mo or W): a comparative study of structure and bonding in [M(CO)5(EPh3)] complexes (E = P, as or Sb; M = Cr, Mo or W)

T. Hambley, M. Davies, M. Aroney, 1994 .

Synthesis, X-Ray Crystal Structure and Magnetic Studies of a Biscopper(II) Complex of a C-Spiro Binucleating Linear Octadentate Ligand

T. Hambley, L. Gahan, G. Hanson, 1990 .

Oxidative Addition of the Dithiobis(formamidinium) Cation to Platinum(II) Chloro Am(m)ine Compounds: Studies on Structure, Spectroscopic Properties, Reactivity, and Cytotoxicity of a New Class of Platinum(IV) Complexes Exhibiting S-Thiourea Coordination.

John D. Roberts, T. Hambley, N. Farrell, 1996, Inorganic chemistry.

Structure of (2,2'-bipyridyl)tetrachloroplatinum(IV)

T. Hambley, T. W. Hambley, 1986 .

Molecular modeling of inorganic compounds

Peter Comba, Trevor W. Hambley, Bodo Martin, 1995 .

A precise low-temperature crystal structure of Bis(cyclopentadienyl)beryllium

T. Hambley, J. Beattie, K. Nugent, 1984 .

Synthesis, structure, electrochemistry, and ligand activity of the dioxobis(.mu.-sulfido)bis(dithiocarbamato)dimolybdenum(V) complex

M. R. Snow, T. Hambley, G. Lawrance, 1984 .

Redetermination of the crystal structure of hexaamminecobalt(II) chloride

T. Hambley, H. C. Freeman, J. Newman, 1991 .

Chelate-ring-opened adducts of[Pt(en)(Me-Mal-O,O′)](en = ethane-1,2-diamine,Me-Mal = 2-methylmalonate) with methionine derivatives:relevance to the biological activity of platinum anticanceragents

P. Sadler, T. Hambley, Zijian Guo, 1997 .

A study of the polarities, anisotropic polarisabilities and carbonyl infrared vibrational frequencies of the complexes [M(CO)5{P(OCH2)3CMe}](M = Cr, Mo or W) and the crystal structure of [Mo(CO)5{P(OCH2)3CMe}]: evidence for π-acceptor behaviour in co-ordinated phosphorus

T. Hambley, M. Davies, M. Aroney, 1994 .

A study of polarities, polarisabilities and infrared spectra of LM(CO)5 complexes (M=Cr, Mo or W; L=trimethylamine, quinuclidine, pyridine, p-methyl- or p-t-butylpyridine) and of the X-ray crystal structure of quinuclidine-Cr(CO)5; evidence for π-acceptor behaviour of coordinated pyridine

T. Hambley, R. Clarkson, M. Aroney, 1992 .

Cyclopentadienyl-ruthenium and -osmium chemistry: XXIV. Some complexes containing the olefinic tertiary phosphine 2-CH2CHC6H4PPh2 (sp): X-ray structures of one isomer of OsBr(sp)(η-C5H5), and of Ru(η3-S2CCHMeC6H4PPh2-2)(η-C5H5), containing an η3-dithiocarboxylato group

M. R. Snow, T. Hambley, M. Bruce, 1984 .

Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding

T. Hambley, D. Fairlie, L. Grøndahl, 2000 .

Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

T. Hambley, B. Palmer, B. Baguley, 2000, British Journal of Cancer.

Cyclopentadienylruthenium and -osmium chemistry. 33. Cyclobutenyl-nitrile complexes. X-ray structure of Ru[C:CPhC(CF3)2C(CN)2](NCMe)(PPh3)(.eta.-C5H5) and [Ru[C:CPhC(CF3)2C(CN)2](PPh3)(.eta.-C5H5)]2[.mu.-(NC)2C:C(CF3)2]

E. Tiekink, T. Hambley, M. Liddell, 1990 .

Reactions of transition-metal .sigma.-acetylide complexes. 14. Cyclobutenyl, butadienyl, and allyl complexes of ruthenium derived from 1,1-dicyano-2,2-bis(trifluoromethyl)ethene. X-ray structures of [cyclic] Ru[C:CPhC(CF3)2C(CN)2](CO)(PPh3)(.eta.-C5H5), Ru[C(:C(CN)2)CX:C(CF3)2](CO)(PPh3)(.eta.-C5H5)

M. R. Snow, E. Tiekink, T. Hambley, 1990 .

A NEW RESOLUTION PROCEDURE FOR THE PREPARATION OF BOTH (R)-(+)-AND (S)-(-)-4-TERT-BUTOXYCYLCOPENT-2-ENONE FROM RACEMIC 4-TERT-BUTOXYCYLOPENT-2-ENONE A ND CONVERSION OF (R)-(+)-4-TERT-BUTOXYCYCLOPENT-2-ENONE INTO (R)-(+)-4-ACET OXYCYLOPENT-2-ENONE. A NEW METHOD FOR THE DETERMINATION OF THE ENANTIOMER

T. Hambley, R. Haynes, D. Ridley, 1991 .

Crystal Structures of (3S*,4S*,5S*,6S*)-3,4-Epoxy- 1,7-dioxaspiro[5.5]undecan-5-ol, (3R*,5S*,6S*)-1,7- Dioxaspiro[5.5]undecane-3,5-diyl Diacetate and (4S*,5S*,6S*)-1,7-Dioxaspiro[5.5]undecane-4,5-diol

T. Hambley, M. Brimble, P. Turner, 1997 .

TWO DIFFERENT TYPES OF FOLDING OF ISOMERIC MACROCYCLES INDUCED BY METAL ION CO-ORDINATION

P. Comba, T. Hambley, A. Fath, 1997 .

1. METALS IN MEDICINE KEYNOTE LECTURES KL01 The mitochondrial cell death pathway as a target for gold and other metal-based antitumour compounds

T. Hambley, S. Berners‐Price, 2007 .

Oxidation of Manganese(II) by Peroxomonosulfuric Acid in Aqueous Solution in the Presence of Molybdate. Crystal-Structure of the K6[MnMo9O32].6H2O Product

T. Hambley, G. Lawrance, R. Burns, 1992 .

Platination of a GG site on single-stranded and double-stranded forms of a 14-base oligonucleotide with diaqua cisplatin followed by NMR and HPLC -- influence of the platinum ligands and base sequence on 5'-G versus 3'-G platination selectivity.

P. Sadler, T. Hambley, A. Corazza, 1997, European journal of biochemistry.

Calculation of the hydrophobicity of platinum drugs.

J. Platts, M. Hall, D. Hibbs, 2001, Journal of medicinal chemistry.

The preparation and characterisation of cyclam/anthraquinone macrocyle/intercalator complexes and their interactions with DNA

T. Hambley, P. Turner, L. T. Ellis, 2003 .

Neutron diffraction studies on natural heulandite and partially dehydrated heulandite

J. C. Taylor, T. Hambley, 1984 .

Analysis of warfarin enantiomers: Chromatographic separation of six stereoisomeric esters prepared from (−)‐(1S,2R,4R)‐endo‐1,4,5,6,7,7‐hexachlorobicyclo[2.2.1]hept‐5‐ene‐2‐ carboxylic acid

T. Hambley, D. Cutler, G. Holder, 1994 .

Reactions of the cis-Diamminediaquaplatinum(II) Cation with Glycinamide, N-Glycylglycine, and N-(N-Glycylglycyl)glycine. Crystal Structure of a Complex with Two Diammineplatinum(II) Cations Bound to Glycylglycinate

T. Hambley, P. Prenzler, T. Appleton, 1990 .

Preparation, characterization, DNA binding, and in vitro cytotoxicity of the enantiomers of the platinum(II) complexes N-methyl-, N-ethyl- and N,N-dimethyl-(R)- and -(S)-3-aminohexahydroazepinedichloroplatinum(II).

T. Hambley, P. Russell, M. McKeage, 1997, Journal of medicinal chemistry.

Preparation, DNA binding, and in vitro cytotoxicity of a pair of enantiomeric platinum(II) complexes, [(R)- and (S)-3-aminohexahydroazepine]dichloroplatinum(II). Crystal structure of the S enantiomer.

T. Hambley, P. Russell, S. O'Mara, 1997, Journal of medicinal chemistry.

THREE NEW PLATINUM(II)-DIPEPTIDE COMPLEXES

D. Shi, T. Hambley, H. C. Freeman, 1999 .

The fate of platinum(II) and platinum(IV) anti-cancer agents in cancer cells and tumours.

B. Lai, M. Hall, P. Beale, 2006, Journal of structural biology.

Transport kinetics of four- and six-coordinate platinum compounds in the multicell layer tumour model

M. Hall, T. Roose, T. Hambley, 2007, British Journal of Cancer.

Observation of a manganese(IV) transient following oxidation of the trans-dichloro(meso-5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane) manganese(III) ion with hydroxyl radical

T. Hambley, G. Lawrance, D. Sangster, 1985 .

Hexamethylmelamine: a study of solvation and crystallisation

T. Hambley, H. Chan, I. Gonda, 1987 .

Crystal and molecular structure of methotrexate

Hak-Kim Chan, T. Hambley, H. Chan, 1986 .

Applications of molybdenum-95 N.M.R. spectroscopy. VI. 95Mo and 13C N.M.R. of certain cis-dioxomolybdenum(VI) compounds and related species. The crystal and molecular structure of Bis(N,N-diethylhydroxylamido(l -)-O,N)- disulfidomolybdenum(VI) hemibenzene

T. Hambley, A. G. Wedd, R. Brownlee, 1982 .

Crystal Structure of Na9[H3W12O42]·24H2O, a Compound Containing the Protonated Paratungstate B Anion ('Acid Paratungstate'), and Cyclic Voltammetry of Acidified [H2W12O42]10- Solutions

T. Hambley, G. Lawrance, R. Burns, 1999 .

Cobalt(III) complexes of 1,5,9-triamino-5-methyl-3,7-diazanonane, L1, a new quinquedentate polyamine ligand. Crystal structures of the chlorocobalt(III) and µ-superoxo-dicobalt(III) complexes of L1

T. Hambley, G. Lawrance, P. Bernhardt, 1990 .

Idiospermuline, a trimeric pyrrolidinoindoline alkaloid from the seed of Idiospermum australiense.

T. Hambley, C. Duke, R. Allan, 1995, Journal of natural products.

Synthesis, Characterization, and Crystal Structure of a Vanadium(V)-Vanadium(IV)-Vanadium(V) Mixed-Valence Trinuclear Complex with a Tridentate Quinato Ligand, (NH4)2{[VV(O)2]2[VIV(O)](.mu.-(-)-quinato(3-))2}.cntdot.H2O

P. A. Lay, T. Hambley, R. Codd, 1995 .

Platinum‐Based Anticancer Agents

T. Hambley, A. V. Klein, 2014 .

The first examples of platinum amine hydroxamate complexes: structures and biological activity

M. Hall, T. Hambley, T. Failes, 2003 .

Platinum(IV) anticancer complexes.

M. Hall, T. Hambley, Rachael C. Dolman, 2004, Metal ions in biological systems.

Metal complexes of phenothiazine based pharmaceuticals: A study of their chemistry and biological effects

T. Hambley, J. Molnár, A. Hevér, 1995 .

Skeletal deformation in 4,5-disubstituted 9,10-dihydrophenanthrenes and 4,5-disubstituted phenanthrenes

T. Hambley, S. Sternhell, R. Cosmo, 1987 .

Targeted cancer therapeutics.

T. Hambley, W. Hait, William N Hait, 2009, Cancer research.

[Pt(2)Cl(2)(&mgr;(2)-O(2))(2)([9]aneN(3))(2)]Cl(2): A Novel Platinum(IV) Dimer with Two Bridging Peroxo Ligands that Provides Insight into the Mechanism of Aerial Oxidation of Platinum(II).

T. Hambley, M. Davies, 1998, Inorganic chemistry.

Is anticancer drug development heading in the right direction?

T. Hambley, W. Hait, William N Hait, 2009, Cancer research.

The cellular distribution and oxidation state of platinum(II) and platinum(IV) antitumour complexes in cancer cells

B. Lai, M. Hall, P. Beale, 2003, JBIC Journal of Biological Inorganic Chemistry.

[1H, 15N] heteronuclear single quantum coherence NMR study of the mechanism of aquation of platinum(IV) ammine complexes.

M. Hall, T. Hambley, S. Berners‐Price, 2008, Inorganic chemistry.

Determination of the crystal structure of a petroporphyrin isolated from oil shale

J. C. Taylor, T. Hambley, S. A. Miller, 1983, Nature.

Stereoselective peripheral sensory neurotoxicity of diaminocyclohexane platinum enantiomers related to ormaplatin and oxaliplatin.

T. Hambley, M. McKeage, H. Er, 1997, British Journal of Cancer.

Radiosynthesis and 'click' conjugation of ethynyl-4-[(18)F]fluorobenzene--an improved [(18)F]synthon for indirect radiolabeling.

T. Hambley, I. Greguric, T. Pham, 2015, Journal of labelled compounds & radiopharmaceuticals.

The use of spectroscopic imaging and mapping techniques in the characterisation and study of DLD-1 cell spheroid tumour models.

Martin D de Jonge, Nicole S. Bryce, M. D. de Jonge, 2012, Integrative biology : quantitative biosciences from nano to macro.

Chiral Tetraamines Based on (S)‐2‐(Aminomethyl)pyrrolidine: Template synthesis and properties of copper(II) complexes

P. Comba, T. Hambley, K. Várnagy, 1992 .

Resolution of racemic amino acids via stereoselective ligand-exchange reactions on an optically pure nickel(II) complex

P. Comba, T. Hambley, K. Várnagy, 1993 .

The composition and end-group functionality of sterically stabilized nanoparticles enhances the effectiveness of co-administered cytotoxins.

Brian S. Hawkett, Nicole S. Bryce, R. Whan, 2013, Biomaterials science.

The reduction of cis-platinum(iv) complexes by ascorbate and in whole human blood models using 1H NMR and XANES spectroscopy.

T. Hambley, P. Kappen, Catherine K J Chen, 2019, Metallomics : integrated biometal science.

Novel formation of isomeric bicyclo[3.2.0]heptan-1-ols from phenyl vinyl sulfoxide and the cyclopentanone lithium enolate generated by conjugate addition of lithiated (E)-but-2-enyldiphenylphosphine oxide to 2-methylcyclopent-2-enone

T. Hambley, W. A. Loughlin, R. Haynes, 1991 .

Structures of dichloro[(S)-methionine-N,S]platinum(II) and chloro[glycyl-(S)-methioninato-N,N',-S]platinum(II) monohydrate

T. Hambley, M. Scudder, H. C. Freeman, 1992 .

Transporter and protease mediated delivery of platinum complexes for precision oncology

T. Hambley, 2019, JBIC Journal of Biological Inorganic Chemistry.

Two unusual formate-bridged manganese(III) tetraphenylporphyrin complexes

T. Hambley, B. Skelton, A. White, 1992 .

Regiochemistry of formation, stereochemistry, and interconversion of .alpha.-tert-butyl-(4- or 5-nitro-N-methyl-2-pyrrolyl)methyl sulfones and sulfinates

T. Hambley, R. K. Norris, M. Harsanyi, 1988 .

Immobilization of Platinated and Iodinated Oligonucleotides on Carbon Nanotubes

Malcolm L. H. Green, Trevor W. Hambley, Shik Chi Tsang, 1997 .

A redetermination of the crystal structure of 'Thorium(IV) Tetrakis(trifluoroacetylacetonate)': Stereochemistry of the system [M(bidentate ligand)4(unidentate ligand)x±

Trevor W. Hambley, Colin L. Raston, T. Hambley, 1978 .

X-ray absorption spectroscopic studies of chromium(V/IV/III)- 2-ethyl-2-hydroxybutanoato(2-/1-) complexes.

P. A. Lay, T. Hambley, T. Maschmeyer, 2004, Inorganic chemistry.

Crystal and molecular structure of the mixed-valence ruthenium dimer tris(.mu.-bromo)bis(triammineruthenium)(2+) tetrabromozincate(II), [(NH3)3RuBr3Ru(NH3)3](ZnBr4)

N. Hush, T. Hambley, J. Beattie, 1988 .

trans-Platinum(iv) pro-drugs that exhibit unusual resistance to reduction by endogenous reductants and blood serum but are rapidly activated inside cells: 1H NMR and XANES spectroscopy study.

T. Hambley, D. Gibson, P. Kappen, 2020, Dalton transactions.

COORDINATION OF THE SEXIDENTATE MACROCYCLE 6,13-DIMETHYL-1,4,8,11-TETRAAZACYCLOTETRADECANE-6,13-DIAMINE TO IRON(III)

P. Comba, T. Hambley, G. Lawrance, 1991 .

Enforced coordination of chromium(III) to a thioether donor in an encapsulated complex

T. Hambley, L. Gahan, R. Stranger, 1993 .

Examination of the effects of oxidation and ring closure on the cytotoxicities of the platinum complexes of N-(2-hydroxyethyl)ethane-1,2-diamine and ethane-1,2-diamine-N,N'-diacetic acid.

T. Hambley, M. McKeage, M. Davies, 2002, Journal of inorganic biochemistry.

Crystal Structure of Calcium Picrate Pentahydrate: A New Eight-Coordinate Stereochemistry for [M(bidentate)2(unidentate)4]

T. Hambley, C. Raston, A. White, 1979 .

Increased targeting of adenine-rich sequences by (2-amino-2-methyl-3-butanone oxime)dichloroplatinum(II) and investigations into its low cytotoxicity

T. Hambley, P. Russell, S. O'Mara, 2000, JBIC Journal of Biological Inorganic Chemistry.

Synthesis and complexation of a chiral sexidentate pendant-arm macropolycyclic polyamino acid

M. Maeder, T. Hambley, G. Lawrance, 2002 .

Characterization of the Minor cis Isomer of a Dipendant Polyamino Acid Macrocycle as a Dimeric Nickel(II) Complex

M. Maeder, T. Hambley, G. Lawrance, 2000 .

Quinquedentate Coordination of 3-[(2'-Amino-ethyl)amino]-2-[(2″-aminoethyl)aminomethyl]propionic Acid (LH). Crystal Structure of trans-[Co(L)Cl][ClO4].H2O And Molecular Mechanics Examination of Isomers

K. J. Molloy, T. Hambley, G. Lawrance, 1994 .

Chlorometal(III) complexes of a new chiral quinquedentate polyamino acid based on (SS)-trans-cyclohexane-1,2-diamine

M. Maeder, T. Hambley, Geoffrey A. Lawrence, 1994 .

A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo

P. A. Lay, P. Barter, T. Hambley, 2016, Cell & Bioscience.

The preparation, characterisation, and DNA adduct profile of 2-amino-2-methyl-3-butanoneoximedichloroplatinum(II), a platinum(II) complex designed to bind to GpA sequences of DNA.

T. Hambley, G. W. Allen, K. Vickery, 2000, Journal of inorganic biochemistry.

Rates of Platination of AG and GA Containing Double-Stranded Oligonucleotides: Insights into Why Cisplatin Binds to GG and AG but Not GA Sequences in DNA

T. Hambley, S. Berners‐Price, M. Davies, 1998 .

Molecular mechanics analysis of the stereochemical factors influencing monofunctional and bifunctional binding of cis-diamminedichloroplatinum(II) to adenine and guanine nucleobases in the sequences d(GpApGpG).cntdot.d(CpCpTpC) and d(GpGpApG).cntdot.d(CpTpCpC) of A- and B-DNA

T. Hambley, 1991 .

The preparation and characterisation of some aminesulfoxidedichloroplatinum(II) complexes

T. Hambley, G. W. Allen, E. C. Ling, 1993 .

Why does cisplatin bind to ApG but not GpA sequences of DNA? A molecular mechanics analysis

T. Hambley, 1988 .

The influence of the ethane-1,2-diamine ligand on the activity of a monofunctional platinum complex.

Blaine R. Roberts, T. Hambley, B. Roberts, 2017, Journal of inorganic biochemistry.

The electron density in flavones I. Baicalein

D. Hibbs, T. Hambley, J. Overgaard, 2003 .

Quinquedentate co-ordination of amino-substituted tetraazacycloalkanes to cobalt(III). Part 2. Crystal structures of trans isomers, molecular mechanics calculations and base-hydrolysis kinetics

T. Hambley, G. Lawrance, B. Skelton, 1992 .

The in situ generation of alk-1-ynyllead triacetates from terminal acetylenes by zinc–lead exchange and crystal structure of 2,4,7,9,13-pentamethyl-9-phenylethynyl-7,10-ethenospiro[5.5]undeca-1,4- diene-3,8-dione

T. Hambley, C. Parkinson, J. Pinhey, 1997 .

Mechanism of arylation of nucleophiles by aryllead triacetates. Part 3. Concerning their reaction with phenols and X-ray molecular structure of p-methoxyphenyllead triacetate

T. Hambley, J. Morgan, J. Pinhey, 1996 .

Reaction of 2,6-disubstituted phenols with vinyllead triacetates and alk-1-ynyllead triacetates: synthesis of 6-vinyl- and 6-alkynyl-cyclohexa-2,4-dienones and crystal structure of 1,3,5,7-tetramethyl-3,5-bis(phenylethynyl)-1,3,4,4a,5,8a-hexahydro-1,4-ethenonaphthalene-2,6-dione

T. Hambley, C. Parkinson, R. J. Holmes, 1992 .

Base-promoted eliminations within halogenated [n.m.1]propellene frameworks

M. R. Snow, T. Hambley, M. Banwell, 1992 .

The impact of highly electron withdrawing carboxylato ligands on the stability and activity of platinum(IV) pro-drugs

T. Hambley, Catherine K J Chen, 2019, Inorganica Chimica Acta.

DNA Binding of a Platinum(II) Complex Designed To Bind Interstrand but Not Intrastrand

T. Hambley, G. W. Allen, E. C. Ling, 1994 .

TRISHOMOCUBANES, A NEW CLASS OF SELECTIVE AND HIGH AFFINITY LIGANDS FOR THE SIGMA BINDING SITE

T. Hambley, M. Kassiou, M. Christie, 1996 .

Structural and X-ray photoelectron spectroscopic properties of hydrophobic cobalt(III) cage complexes with dithiocarbamate anions

T. Hambley, L. Gahan, P. Healy, 1989 .

The nature of close Pd⋯Pd and Pd⋯H(—C) contacts

T. Hambley, F. Huq, R. Fenton, 1999 .

Formation of ruthenium thiolates via complexes of molecular hydrogen

T. Hambley, L. Field, B. Yau, 1994 .

Platinum(IV) analogues of AMD473 (cis-[PtCl2(NH3)(2-picoline)]): preparative, structural, and electrochemical studies.

D. Hibbs, T. Hambley, A. Battle, 2006, Inorganic chemistry.

Trishomocubanes: Requirements for σ Receptor Binding and Subtype Selectivity

T. Hambley, M. Kassiou, M. Christie, 2001 .

Iron(III) complexes of fluorescent hydroxamate ligands: preparation, properties, and cellular processing.

T. Hambley, P. Jensen, Natsuho Yamamoto, 2009, Dalton transactions.

Highly diastereoselective conjugate addition of lithiated gamma-crotonolactone (but-2-en-4-olide) to cyclic enones to give syn-adducts: Application to a brefeldin synthesis

Ian D. Williams, T. Hambley, R. Haynes, 1997 .

Interactions of cisplatin and the copper transporter CTR1 in human colon cancer cells

T. Hambley, E. New, M. C. Åkerfeldt, 2017, JBIC Journal of Biological Inorganic Chemistry.

Metal-Based Therapeutics

T. Hambley, 2007, Science.

Platinum Drug Distribution in Cancer Cells and Tumors

T. Hambley, A. V. Klein, 2010 .

Catalysis by hamster dihydroorotase: zinc binding, site-directed mutagenesis, and interaction with inhibitors.

N. K. Williams, S. O’Donoghue, R. Christopherson, 1995, Biochemistry.

Syntheses and characterization of anti-inflammatory dinuclear and mononuclear zinc indomethacin complexes. Crystal structures of [Zn2(indomethacin)4(L)2] (L = N,N-dimethylacetamide, pyridine, 1-methyl-2-pyrrolidinone) and [Zn(indomethacin)2(L1)2] (L1 = ethanol, methanol).

P. A. Lay, T. Hambley, B. Kennedy, 2000, Inorganic Chemistry.

Oxidation of [PtIICl2(ethane-1,2-diamine-N,N'-dicarboxylic Acid)] and Ligand Ring Closure in the Platinum(IV) Oxidation State

T. Hambley, M. Davies, Pong Nai Wong, 2001 .

Synthesis and Crystal Structures of [Fe(bpe6)2Cl2] and [Fe(bpe6)2Cl2]+ [FeCl4]¿ (bpe6 = 1,2-Bis(phosphorinan-1-yl)ethane)

T. Hambley, L. Field, P. Turner, 2000 .

Synthesis and exchange reactions of 5-alkyl-2-oxo-6-thioxo-1,2,3,6-hexahydropyrimidine-4-carboxylic acids

R. Christopherson, T. Hambley, J. Kirk, 1997 .

Cyclopentadienyl-ruthenium and -osmium chemistry. XIX. Some complexes containing η2-olefin, η2-allene and η2-alkyne ligands

J. Rodgers, T. Hambley, F. Wong, 1982 .

Insights into bonding and hydrogen bond directionality in thioacetamide from the experimental charge distribution

D. Hibbs, T. Hambley, M. Hursthouse, 2002 .

A force field for molecular mechanics modeling of cobalt(II) amine complexes and a new model of electron transfer for cobalt(III)-cobalt(II) redox couples

M. R. Snow, A. Bond, T. Hambley, 1985 .

Fluorescent analogues of quinoline reveal amine ligand loss from cis and trans platinum(II) complexes in cancer cells.

T. Hambley, Jenny Z. Zhang, Elizabeth J. New, 2009, Journal of Inorganic Biochemistry.

Isomer formation in the binding of [PtCl2(cis-cyclohexane-1,3-diamine)] to oligonucleotides and the X-ray crystal structure of [PtCl2(cis-cyclohexane-1,3-diamine)]·dimethylformamide

T. Hambley, L. T. Ellis, B. Messerle, 2001 .

What can be learnt from computer-generated models of interactions between DNA and Pt(II) based anti-cancer drugs

T. Hambley, 1992 .

Electrochemistry of the quasi-reversible bis[2-ethyl-2-hydroxybutanoato(2–)]-oxochromate-(V) and -(IV) and bis[2-hydroxy-2-methylbutanoato(2–)]oxochromate-(V) and -(IV) redox couples and the crystal and molecular structure of sodium bis[2-ethyl-2-hydroxybutanoato(2–)]oxochromate(V)sesquihydrate

P. A. Lay, T. Hambley, R. Judd, 1989 .