A. Ramirez

发表

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.

Melissa A. Basford, J. Haines, D. Roden, 2010, American journal of human genetics.

Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record.

Melissa A. Basford, Raquel M. Zink, D. Roden, 2012, Pharmacogenomics.

Identification of Genomic Predictors of Atrioventricular Conduction: Using Electronic Medical Records as a Tool for Genome Science

Melissa A. Basford, J. Haines, D. Roden, 2010, Circulation.

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.

Melissa A. Basford, C. Chute, T. Manolio, 2011, American journal of human genetics.

Operational Implementation of Prospective Genotyping for Personalized Medicine: The Design of the Vanderbilt PREDICT Project

E. Clayton, J. Schildcrout, J. Peterson, 2012, Clinical pharmacology and therapeutics.

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

Melissa A. Basford, Raquel M. Zink, J. Haines, 2013, Nature Biotechnology.

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

Joshua C. Denny, Lisa Bastarache, Wei-Qi Wei, 2018, Science.

Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk

Melissa A. Basford, C. Carlson, J. Haines, 2013, Circulation.

Predicting Clopidogrel Response Using DNA Samples Linked to an Electronic Health Record

D. Roden, J. Schildcrout, M. Ritchie, 2012, Clinical pharmacology and therapeutics.

Generalization of Variants Identified by Genome‐Wide Association Studies for Electrocardiographic Traits in African Americans

Melissa A. Basford, Janina M. Jeff, Wendy A. Wolf, 2013, Annals of human genetics.

Genome-wide study of resistant hypertension identified from electronic health records

Melissa A. Basford, Marc S. Williams, C. Chute, 2017, PloS one.

Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.

Yan Guo, Yu Shyr, Dan M Roden, 2014, Journal of the American College of Cardiology.

A Common 5′‐UTR Variant in MATE2‐K Is Associated With Poor Response to Metformin

J. Mefford, J. Witte, P. Kwok, 2011, Clinical pharmacology and therapeutics.

Modulators of normal ECG intervals identified in a large electronic medical record

Melissa A. Basford, D. Roden, J. Denny, 2011 .

Genome-and Phenome-Wide Analysis of Cardiac Conduction Identifies Markers of Arrhythmia Risk Running title : Ritchie et al . ; QRS GWAS and PheWAS in electronic records

Christopher G. Chute, Marylyn D. Ritchie, Joshua C. Denny, 2013 .

Building evidence and measuring clinical outcomes for genomic medicine

Marc S. Williams, D. Roden, G. Mensah, 2019, The Lancet.

A genome-wide association study of polycystic ovary syndrome identified from 1 electronic health records

Dustin N. Hartzel, Jacob M. Keaton, H. Hakonarson, 2019 .

Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes

D. Harlan, R. Hegele, L. Philipson, 2021, Journal of the Endocrine Society.

Physician-Reported Benefits and Barriers to Clinical Implementation of Genomic Medicine: A Multi-Site IGNITE-Network Survey

A. Ramirez, T. Pollin, Aniwaa Owusu Obeng, 2018, Journal of personalized medicine.

IGNITE network: Response of patients to genomic medicine interventions

Ebony B. Madden, C. Voils, A. Ramirez, 2019, Molecular genetics & genomic medicine.

Carrying one or two reduced-function CYP2C19 alleles is associated with an increased risk of major adverse cardiovascular events in people undergoing percutaneous coronary intervention and treated with clopidogrel

A. Shuldiner, A. Ramirez, J. Delaney, 2011, Evidence Based Medicine.

Multiplex ligation-dependent probe amplification copy number variant analysis in patients with acquired long QT syndrome.

D. Roden, A. Ramirez, Tao Yang, 2015, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Whole Exome Sequencing Identifies a Causal RBM20 Mutation in a Large Pedigree With Familial Dilated Cardiomyopathy

Dan M Roden, Quinn S Wells, Charles C Hong, 2013, Circulation. Cardiovascular genetics.

Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci

Marylyn D. Ritchie, Joshua C. Denny, Shefali S. Verma, 2014, Molecular vision.

Phenotypic Profiling in Subjects Heterozygous for 1 of 2 Rare Variants in the Hypophosphatasia Gene (ALPL)

J. Meiler, A. Ramirez, J. Capra, 2020, Journal of the Endocrine Society.

Rare Variants in the Gene ALPL That Cause Hypophosphatasia Are Strongly Associated With Ovarian and Uterine Disorders

J. Denny, J. Warner, A. Gifford, 2018, Journal of Clinical Endocrinology and Metabolism.

Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network.

Robert C. Green, Keith Marsolo, Casey Overby Taylor, 2019, American journal of human genetics.

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals

Mohamed H. Shahin, P. Deloukas, R. Altman, 2019, Clinical pharmacology and therapeutics.

Optimizing Drug Outcomes Through Pharmacogenetics: A Case for Preemptive Genotyping

Melissa A. Basford, J M Pulley, D M Roden, 2012, Clinical pharmacology and therapeutics.

Arrhythmia Risk Genome-and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of

Melissa A. Basford, C. Carlson, J. Haines, 2013 .

Modulators of normal electrocardiographic intervals identified in a large electronic medical record.

Joshua C Denny, Dan M Roden, Melissa A. Basford, 2011, Heart rhythm.

A genome-wide association study of polycystic ovary syndrome identified from electronic health records.

Dustin N. Hartzel, Jacob M. Keaton, Marc S. Williams, 2020, American journal of obstetrics and gynecology.

The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin

C. McCarty, D. Roden, R. Wilke, 2013, Clinical pharmacology and therapeutics.

Novel Rare Variants in Congenital Cardiac Arrhythmia Genes are Frequent in Drug-induced Torsades de Pointes

M. Rieder, D. Nickerson, D. Roden, 2012, The Pharmacogenomics Journal.

Genetic determinants of variability in warfarin response after the dose-titration phase

D. Roden, J. Denny, J. Schildcrout, 2016, Pharmacogenetics and genomics.

Characterizing variability of electronic health record-driven phenotype definitions

Nephi A. Walton, H. Hakonarson, J. Pathak, 2022, J. Am. Medical Informatics Assoc..

A genome-wide association study of polycystic ovary syndrome identified from electronic health records.

Dustin N. Hartzel, Jacob M. Keaton, Marc S. Williams, 2019, American journal of obstetrics and gynecology.

Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin

Hua Xu, Marylyn D. Ritchie, Joshua C. Denny, 2011, J. Am. Medical Informatics Assoc..

Next-Generation Phenotyping: Introducing PhecodeX for Enhanced Discovery Research in Medical Phenomics

J. Warner, B. Malow, W. Stead, 2023, medRxiv.

Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci

Robert J. Goodloe, Wendy A. Wolf, C. Carlson, 2014, Molecular vision.

Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk

Melissa A. Basford, C. Carlson, C. Chute, 2013, Circulation.

Operational Implementation of Prospective Genotyping for Personalized Medicine: The Design of the Vanderbilt PREDICT Project

E. Clayton, J. Schildcrout, J. Peterson, 2012, Clinical pharmacology and therapeutics.

Abstract 19509: Identifying Genotype-Phenotype Relations in Electronic Medical Record Systems: Application to Warfarin Pharmacogenomics.

Marylyn D. Ritchie, Joshua C. Denny, Dana C. Crawford, 2010 .

Abstract 12560: Targeted Next Generation Exomic Sequencing of Cardiac Electrophysiology Genes in Cases of Drug-Induced Torsades de Pointes

D. Roden, S. Levy, A. Ramirez, 2010 .

Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions

George Hripcsak, Chunhua Weng, Jennifer A. Pacheco, 2021, BMC Medical Informatics and Decision Making.

Predicting Clopidogrel Response Using DNA Samples Linked to an Electronic Health Record

Melissa A. Basford, Raquel M. Zink, D. Roden, 2012, Clinical pharmacology and therapeutics.

Interactions between genetic variation and cellular environment in skeletal muscle gene expression

Stephen C. J. Parker, David A. Knowles, E. Birney, 2017, bioRxiv.