Joanna L. Parmley

Hearing silence: non-neutral evolution at synonymous sites in mammals

L. Hurst, J. Chamary, Joanna L. Parmley, 2006, Nature Reviews Genetics.

How do synonymous mutations affect fitness?

L. Hurst, Joanna L. Parmley, Laurence D Hurst, 2007, BioEssays : news and reviews in molecular, cellular and developmental biology.

Evidence for purifying selection against synonymous mutations in mammalian exonic splicing enhancers.

L. Hurst, J. Chamary, Joanna L. Parmley, 2006, Molecular biology and evolution.

How Common Are Intragene Windows with KA > KS Owing to Purifying Selection on Synonymous Mutations?

L. Hurst, Joanna L. Parmley, 2007, Journal of Molecular Evolution.

Clustering of Codons with Rare Cognate tRNAs in Human Genes Suggests an Extra Level of Expression Regulation

Martijn A. Huynen, M. Huynen, Joanna L. Parmley, 2009, PLoS genetics.

The fitness cost of mis-splicing is the main determinant of alternative splicing patterns

L. Duret, Joanna L. Parmley, A. Necsulea, 2017, Genome Biology.

The fitness cost of mis-splicing is the main determinant of alternative splicing patterns

L. Duret, Joanna L. Parmley, A. Necsulea, 2017, bioRxiv.

Splicing and the Evolution of Proteins in Mammals

Araxi O. Urrutia, L. Hurst, H. Kaessmann, 2007, Nature Reviews Genetics.

Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes

L. Hurst, Joanna L. Parmley, Tobias Warnecke, 2008, Genome Biology.

Exonic splicing regulatory elements skew synonymous codon usage near intron-exon boundaries in mammals.

L. Hurst, Joanna L. Parmley, Laurence D Hurst, 2007, Molecular biology and evolution.