B. Preston

发表

High Rate of Recombination throughout the Human Immunodeficiency Virus Type 1 Genome

A. Jetzt, Hong-xia Yu, G. Klarmann, 2000, Journal of Virology.

B. Preston, P. Treuting, Tina M. Albertson, 2010, Toxicologic pathology.

Expression of a Human Cytochrome P450 in Yeast Permits Analysis of Pathways for Response to and Repair of Aflatoxin-Induced DNA Damage

L. Breeden, B. Preston, D. Eaton, 2005, Molecular and Cellular Biology.

Human Immunodeficiency Virus Type 1 Recombination: Rate, Fidelity, and Putative Hot Spots

A. Jetzt, G. Klarmann, Y. Ron, 2002, Journal of Virology.

Decoding cell lineage from acquired mutations using arbitrary deep sequencing

B. Preston, A. Kas, S. Salipante, 2011, Nature Methods.

DNA replication fidelity and cancer.

B. Preston, A. Herr, Tina M. Albertson, 2010, Seminars in cancer biology.

Mutator Phenotypes Caused by Substitution at a Conserved Motif A Residue in Eukaryotic DNA Polymerase δ*

L. Loeb, B. Preston, R. Venkatesan, 2006, Journal of Biological Chemistry.

Reactions of 2,2',5,5'-tetrachlorobiphenyl 3,4-oxide with methionine, cysteine and glutathione in relation to the formation of methylthio-metabolites of 2,2',5,5'-tetrachlorobiphenyl in the rat and mouse.

J. Miller, B. Preston, E. Miller, 1984, Chemico-biological interactions.

Antiretroviral drug resistance in HIV-2: three amino acid changes are sufficient for classwide nucleoside analogue resistance.

G. Gottlieb, B. Preston, Robert A. Smith, 2009, The Journal of infectious diseases.

Inhibition of reverse transcriptase from feline immunodeficiency virus by analogs of 2'-deoxyadenosine-5'-triphosphate.

B. Preston, R. Cronn, K. Remington, 1992, Biochemical pharmacology.

Human Immunodeficiency Virus Types 1 and 2 Exhibit Comparable Sensitivities to Zidovudine and Other Nucleoside Analog Inhibitors In Vitro

G. Gottlieb, B. Preston, Robert A. Smith, 2007, Antimicrobial Agents and Chemotherapy.

Mutagenic spectrum resulting from DNA damage by oxygen radicals.

L. Loeb, B. Preston, T. Mcbride, 1991, Biochemistry.

Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

D. Jerina, B. Preston, E. Hennig, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase.

P. Rabinovitch, R. Monnat, B. Preston, 2010, DNA repair.

Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice.

R. Goldsby, B. Preston, L. Hays, 2001, Nature medicine.

The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.

L. Loeb, B. Preston, D. Cahill, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Emergence of DNA Polymerase ε Antimutators That Escape Error-Induced Extinction in Yeast

B. Preston, A. Herr, L. Williams, 2013, Genetics.

Non-arene oxide aromatic ring hydroxylation of 2,2',5,5'-tetrachlorobiphenyl as the major metabolic pathway catalyzed by phenobarbital-induced rat liver microsomes.

J. Miller, B. Preston, E. Miller, 1983, The Journal of biological chemistry.

Apurinic sites as common intermediates in mutagenesis.

R. Schaaper, L. Loeb, B. Preston, 1986, Basic life sciences.

Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis.

L. Loeb, B. Preston, B. Singer, 1986, Proceedings of the National Academy of Sciences of the United States of America.

RETROVIRAL MUTATION AND REVERSE TRANSCRIPTASE FIDELITY

B. Preston, N. Garvey, 1992 .

DNA polymerase δ-dependent repair of DNA single strand breaks containing 3′-end proximal lesions

G. Dianov, B. Preston, J. Parsons, 2007, Nucleic acids research.

DNA polymerase δ-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.

G. Dianov, B. Preston, J. Parsons, 2007, Nucleic acids research.

Mutation at the Polymerase Active Site of Mouse DNA Polymerase (cid:2) Increases Genomic Instability and Accelerates Tumorigenesis (cid:1)

L. Loeb, R. Goldsby, B. Preston, 2007 .

Enzymatic synthesis of site-specifically modified DNA.

L. Loeb, B. Preston, 1988, Mutation research.

Antimutator variants of DNA polymerases

B. Preston, A. Herr, L. Williams, 2011, Critical reviews in biochemistry and molecular biology.

A Novel Point Mutation at Position 156 of Reverse Transcriptase from Feline Immunodeficiency Virus Confers Resistance to the Combination of (−)-β-2′,3′-Dideoxy-3′-Thiacytidine and 3′-Azido-3′-Deoxythymidine

R. Schinazi, B. Preston, K. Remington, 1998, Journal of Virology.

Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines.

B. Preston, T. Helleday, M. Meuth, 2002, Human molecular genetics.

Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

L. Loeb, B. Preston, F. Perrino, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Fidelity of HIV-1 reverse transcriptase.

L. Loeb, B. Preston, B. Poiesz, 1988, Science.

Mutagenesis by apurinic/apyrimidinic sites.

L. Loeb, B. Preston, 1986, Annual review of genetics.

Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors.

E. De Clercq, G. Klarmann, B. Preston, 2002, Molecular pharmacology.

Lethal mutagenesis of HIV.

L. Loeb, B. Preston, Robert A. Smith, 2005, Virus research.

Comparison of the relative mutagenicities of O-alkylthymines site-specifically incorporated into phi X174 DNA.

L. Loeb, B. Preston, B. Singer, 1987, The Journal of biological chemistry.

A genetic system to identify DNA polymerase β mutator mutants

B. Preston, K. Eckert, J. Sweasy, 1997 .

Marked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template ends.

B. Preston, Premal H. Patel, P. Patel, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications

Y. Ron, B. Preston, J. Dougherty, 1995, Journal of virology.

A New Point Mutation (P157S) in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Confers Low-Level Resistance to (−)-β-2′,3′-Dideoxy-3′-Thiacytidine

R. Schinazi, G. Klarmann, B. Preston, 1999, Antimicrobial Agents and Chemotherapy.

Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system

G. Klarmann, B. Preston, J. Dougherty, 1997, Journal of virology.

Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro.

G. Klarmann, B. Preston, C. Schauber, 1993, The Journal of biological chemistry.

Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site

M. Wainberg, B. Roques, E. Arts, 1996, Journal of virology.

Correction: Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast

B. Preston, Mallika Singh, M. Ogawa, 2011, PLoS Genetics.

Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast

B. Preston, Mallika Singh, M. Ogawa, 2011, PLoS genetics.

A high-resolution landscape of mutations in the BCL6 super-enhancer in normal human B cells

Brendan F. Kohrn, K. Loeb, L. Loeb, 2019, Proceedings of the National Academy of Sciences.

Mutation at the Polymerase Active Site of Mouse DNA Polymerase δ Increases Genomic Instability and Accelerates Tumorigenesis

L. Loeb, R. Goldsby, B. Preston, 2007, Molecular and Cellular Biology.

A high-resolution landscape of mutations in the BCL6 super-enhancer in normal human B cells

Brendan F. Kohrn, K. Loeb, L. Loeb, 2019, Proceedings of the National Academy of Sciences.

Ig gene somatic hypermutation in mice defective for DNA polymerase δ proofreading

R. Goldsby, B. Preston, U. Storb, 2003 .

Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading.

R. Goldsby, B. Preston, U. Storb, 2003, International immunology.

DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice

R. Goldsby, B. Preston, P. Treuting, 2009, Proceedings of the National Academy of Sciences.

Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro

T. Kunkel, L. Loeb, B. Preston, 1989, Molecular and cellular biology.

Molecular targets of chemical mutagens.

B. Preston, R. Doshi, 1991, Advances in experimental medicine and biology.

Mutational Analysis of HIV-1 Long Terminal Repeats to Explore the Relative Contribution of Reverse Transcriptase and RNA Polymerase II to Viral Mutagenesis*

Hong Yu, Y. Ron, B. Preston, 2002, The Journal of Biological Chemistry.

The Nature of Human Immunodeficiency Virus Type 1 Strand Transfers*

A. Jetzt, Hong-xia Yu, Y. Ron, 1998, The Journal of Biological Chemistry.

Hypersusceptibility to Substrate Analogs Conferred by Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase

B. Preston, Robert A. Smith, Donovan J. Anderson, 2006, Journal of Virology.

High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading

R. Goldsby, B. Preston, W. Slayton, 2002, Proceedings of the National Academy of Sciences of the United States of America.

High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.

R. Goldsby, B. Preston, W. Slayton, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Transduction of Cellular Sequence by a Human Immunodeficiency Virus Type 1-Derived Vector

Y. Ron, B. Preston, J. Dougherty, 2001, Journal of Virology.

DNA Replication Error-Induced Extinction of Diploid Yeast

Scott R. Kennedy, B. Preston, A. Herr, 2014, Genetics.

replication and repair , polymerase fidelity , cancer , lethal mutagenesis , mutational robustness

Scott R. Kennedy, B. Preston, A. Herr, 2014 .

Incorporation of Uracil into Minus Strand DNA Affects the Specificity of Plus Strand Synthesis Initiation during Lentiviral Reverse Transcription*

G. Klarmann, B. Preston, T. North, 2003, The Journal of Biological Chemistry.

Reverse transcriptase fidelity and HIV-1 variation.

B. Preston, 1997, Science.

Site-specific Incorporation of Nucleoside Analogs by HIV-1 Reverse Transcriptase and the Template Grip Mutant P157S

R. Schinazi, G. Klarmann, B. Preston, 2000, The Journal of Biological Chemistry.

Purifying Selection Masks the Mutational Flexibility of HIV-1 Reverse Transcriptase*

B. Preston, Donovan J. Anderson, R. Smith, 2004, Journal of Biological Chemistry.

Direct evidence that an arene oxide is a metabolic intermediate of 2,2',5,5'-tetrachlorobiphenyl.

B. Preston, S. Forgue, J. Allen, 1979, Biochemical and biophysical research communications.

A random mutation capture assay to detect genomic point mutations in mouse tissue

J. Bielas, L. Loeb, B. Preston, 2011, Nucleic acids research.

Tumorigenesis Genomic Instability and Accelerates Increases δ Mouse DNA Polymerase Mutation at the Polymerase Active Site of

L. Loeb, R. Goldsby, B. Preston, 2007 .

Increased Activity and Fidelity of DNA Polymerase β on Single-nucleotide Gapped DNA*

B. Preston, J. Sweasy, A. Chagovetz, 1997, The Journal of Biological Chemistry.

Effect of human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein on HIV-1 reverse transcriptase activity in vitro.

G. Klarmann, B. Preston, X. Ji, 1996, Biochemistry.

Mouse DNA polymerase ε gene (Pole) maps to Chromosome 5

R. Goldsby, B. Preston, Mallika Singh, 2009, Mammalian Genome.

Defective DNA polymerase-δ proofreading causes cancer susceptibility in mice

R. Goldsby, B. Preston, Mallika Singh, 2001, Nature Medicine.

Comparison of Moloney murine leukemia virus mutation rate with the fidelity of its reverse transcriptase in vitro.

B. Preston, J. Dougherty, A. Varela-Echavarría, 1992, The Journal of biological chemistry.

DNA Replication Fidelity: Proofreading in Trans

B. Preston, T. Albertson, 2006, Current Biology.

Promoting effects of polychlorinated biphenyls (Aroclor 1254) and polychlorinated dibenzofuran-free Aroclor 1254 on diethylnitrosamine-induced tumorigenesis in the rat.

B. Preston, J. Allen, J. V. Van Miller, 1981, Journal of the National Cancer Institute.

Error-prone retrotransposition: rime of the ancient mutators.

B. Preston, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms of retroviral mutation.

B. Preston, J. Dougherty, J. Dougherty, 1996, Trends in microbiology.

2,2',5,5'-Tetrachlorobiphenyl: isolation and identification of metabolites generated by rat liver microsomes.

B. Preston, J. Allen, 1980, Drug metabolism and disposition: the biological fate of chemicals.

Structural Determinants of Slippage-mediated Mutations by Human Immunodeficiency Virus Type 1 Reverse Transcriptase*

T. Darden, S. Sarafianos, E. Arnold, 2006, Journal of Biological Chemistry.

A Mitochondrial view of aging, reactive oxygen species and metastatic cancer

Warren Ladiges, P. Rabinovitch, L. Loeb, 2010, Aging cell.

A genetic system to identify DNA polymerase beta mutator mutants.

B. Preston, K. Eckert, J. Sweasy, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Mouse DNA polymerase δ gene (Pold1) maps to Chromosome 7

R. Goldsby, B. Preston, Mallika Singh, 2009, Mammalian Genome.

Mouse DNA polymerase delta gene (Pold1) maps to chromosome 7.

R. Goldsby, B. Preston, M. Singh, 1998, Mammalian Genome.

DNA replication fidelity and cancer.

B. Preston, A. Herr, T. Albertson, 2010, Seminars in cancer biology.