C. McMartin

发表

The art and practice of structure‐based drug design: A molecular modeling perspective

W. Guida, R. Bohacek, C. McMartin, 1996, Medicinal research reviews.

Modern computational chemistry and drug discovery: structure generating programs.

R. Bohacek, C. McMartin, Colin McMartin, 1997, Current opinion in chemical biology.

Multiple Highly Diverse Structures Complementary to Enzyme Binding Sites: Results of Extensive Application of a de Novo Design Method Incorporating Combinatorial Growth

Regine Bohacek, R. Bohacek, C. McMartin, 1994 .

Assessment of Docking Poses: Interactions-Based Accuracy Classification (IBAC) versus Crystal Structure Deviations.

Anna Vulpetti, Pieter F. W. Stouten, Joseph J. McDonald, 2004 .

Use of octadecasilyl-silica for the extraction and purification of peptides in biological samples. Application to the identification of circulating metabolites of corticotropin-(1-24)-tetracosapeptide and somatostatin in vivo.

C. McMartin, H. Bennett, A. Hudson, 1977, The Biochemical journal.

Abstracts of lectures symposium disposition and delivery of peptide drugs

H. M. Patel, Kevin R. Smith, V. H. Lee, 1988, Pharmaceutisch Weekblad.

Routes of Administration for Polar Compounds of Moderate Molecular Weight with Particular Reference to Analogues of Somatostatin

G. E. Peters, C. McMartin, 1986 .

Purification and characterization of porcine corticotrophin-like intermediate lobe peptide.

C. McMartin, J. Ratcliffe, A. Scott, 1974, The Journal of endocrinology.

Structural studies of α-melanocyte-stimulating hormone and a novel β-melanocyte-stimulating hormone from the neurointermediate lobe of the pituitary of the dogfish Squalus acanthias

C. McMartin, A. Scott, H. Bennett, 1974 .

A rapid method, using octadecasilyl-silica, for the extraction of certain peptides from tissues.

C. McMartin, H. Bennett, A. Hudson, 1978, The Biochemical journal.

PRODUCTION OF A CORTICOTROPHIN‐LIKE INTERMEDIATE LOBE PEPTIDE AND OF CORTICOTROPHIN BY A BRONCHIAL CARCINOID TUMOUR

J. A. Strong, C. McMartin, J. Ratcliffe, 1973, Clinical endocrinology.

Early fate of somatostatin in the circulation of the rat after intravenous injection.

C. McMartin, G. Purdon, 1978, The Journal of endocrinology.

Degradation of Atrial Natriuretic Peptide: Pharmacologic Effects of Protease EC 24.11 Inhibition

C. McMartin, M. B. Zimmerman, R. Webb, 1989, Journal of cardiovascular pharmacology.

Rapid conversion of somatostatin to active metabolite in human plasma

G. E. Peters, A. Czernik, C. McMartin, 1981, FEBS letters.

Peptide hormones and their analogues: distribution, clearance from the circulation, and inactivation in vivo.

C. McMartin, H. Bennett, 1978, Pharmacological reviews.

Isolation and identification of pharmacologically active amino acids in skin and their structure‐activity relationship on the guinea‐pig ileum

C. McMartin, S. Rosenthal, G. Lewis, 1972, British journal of pharmacology.

Rat vascular tissue contains a neutral endopeptidase capable of degrading atrial natriuretic peptide.

M. Erion, C. McMartin, M. Miller, 1989, The Journal of pharmacology and experimental therapeutics.

Fate of human corticotrophin immediately after intravenous administration to the rat.

C. McMartin, H. Bennett, A. Hudson, 1982, The Journal of endocrinology.

Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.

R. Bohacek, C. McMartin, G. Ksander, 1997, Journal of medicinal chemistry.

Abstracts of Dutch doctoral theses

R. A. Zeeuw, G. J. Jong, M. J. M. Zeeland, 2005, Pharmaceutisch Weekblad.

Effects of sodium 5-methoxysalicylate on macromolecule absorption and mucosal morphology in a vascularly perfused rat gut preparation in vivo.

G. E. Peters, C. McMartin, L. Hutchinson, 1987, Journal of pharmaceutical sciences.

Analysis of structural requirements for the absorption of drugs and macromolecules from the nasal cavity.

G. E. Peters, C. McMartin, C McMartin, 1987, Journal of pharmaceutical sciences.

Gas-liquid chromatography of submicrogram amounts of drugs. II. Analysis of barbiturates and related drugs in biological media.

C. McMartin, H. Street, 1966, Journal of chromatography.

Gas-liquid chromatography of submicrogram amounts of drugs. I. Preparation, scope and limitation of columns.

C. McMartin, H. Street, 1966, Journal of Chromatography A.

The specific assay of basic drugs in urine by CM-cellulose chromatography using continuous drug-dye complex extraction as a detection system.

C. McMartin, P. Simpson, N. Thorpe, 1969, Journal of chromatography.

STUDIES ON THE RAPID ANALYSIS OF DRUGS IN HUMAN BODY FLUIDS AND TISSUES. I. ACTION OF CONCENTRATED SULPHURIC ACID ON 5,5DISUBSTITUTED BARBITURIC ACID DERIVATIVES.

C. McMartin, H. Street, 1964, Clinica chimica acta; international journal of clinical chemistry.

Quantitative Estimation and Identification of Barbiturates in Blood in Emergency Cases

C. McMartin, H. Street, 1963, Nature.

Further Studies in the Rapid Identification of Drugs

C. McMartin, H. Street, 1963 .

Characterization of corticotrophin-like intermediate lobe peptides from rat and pig pituitaries, and identification of alpha-melanocyte-stimulating hormone in the rat pituitary.

C. McMartin, J. Ratcliffe, A. Scott, 1973, The Journal of endocrinology.

The isolation and amino acid sequence of an adrenocorticotrophin from the pars distalis and a corticotrophin-like intermediate-lobe peptide from the neurointermediate lobe of the pituitary of the dogfish Squalus acanthias.

C. McMartin, H. Bennett, P. Lowry, 1974, The Biochemical journal.

Pituitary peptide.

C. McMartin, J. Ratcliffe, A. Scott, 1973, Nature: New biology.

Properties of a simplified bioassay for adrenocorticotrophic activity using the steroidogenic response of isolated adrenal cells.

C. McMartin, P. Lowry, J. Peters, 1973, The Journal of endocrinology.

The preparation of high resolution microgranular carboxymethyl cellulose columns and their application to the separation of guanethidine and its metabolites in urine

C. McMartin, J. Vinter, 1969 .

Differences between in-vitro and in-vivo potencies of corticotrophins: an interpretation in terms of metabolic stability.

C. McMartin, P. Sieber, W. Rittel, 1977, The Journal of endocrinology.

Renal uptake and metabolism of adrenocorticotrophin analogues in the rat: an autoradiographic study.

C. McMartin, H. Bennett, J. Baker, 1977, The Journal of endocrinology.

Identification of Novel Small‐molecule Inducers of Fetal Hemoglobin Using Pharmacophore and ‘PSEUDO’ Receptor Models

D. Faller, C. McMartin, M. Boosalis, 2006, Chemical biology & drug design.

Levels of corticotrophin analogues in the blood after infusion into rats.

C. McMartin, J. Peters, 1975, The Journal of endocrinology.

Measurement of the dynamics of stimulation and inhibition of steroidogenesis in isolated rat adrenal cells by using column perfusion.

C. McMartin, P. Lowry, 1974, The Biochemical journal.

Complete amino acid analysis of peptides and proteins after hydrolysis by a mixture of sepharose-bound peptidases.

B. E. Evans, D. F. Elliott, C. McMartin, 1972, The Biochemical journal.

Pharmacokinetics of Peptides and Proteins: Opportunities and Challenges

C. McMartin, 1992 .

A study of the metabolic fate of chlorpropamide in man

C. McMartin, P. Grieveson, P. Brotherton, 1969, Clinical pharmacology and therapeutics.

Disposition of glutethimide in man

S. Curry, C. McMartin, D. Riddall, 1971, Clinical pharmacology and therapeutics.

An investigation of the involvement of adenosine 3':5'-cyclic monophosphate in steroidogenesis by using isolated adrenal cell column perfusion.

C. McMartin, A. Hudson, 1975, The Biochemical journal.

Three-Dimensional Models of ACE and NEP Inhibitors and Their Use in the Design of Potent Dual ACE/NEP Inhibitors

Regine Bohacek, R. Bohacek, C. McMartin, 1996 .

Peptide and Protein Drugs

C. McMartin, 1994 .

Accurate binding site models can be derived from low quality PDB files using an empirical geometry based force field

Colin McMartin, Regine Bohacek, R. Bohacek, 2013 .

Distribution and degradation of two tritium-labelled corticotrophin analogues in the rat.

C. McMartin, H. Bennett, 1979, The Journal of endocrinology.

Pharmacokinetics, distribution and elimination of a synthetic octapeptide analogue of somatostatin in the rat

G. E. Peters, C. McMartin, B. H. Kemmenoe, 1984, Regulatory Peptides.

Metabolism of two adrenocorticotrophin analogues in the intestine of the rat.

C. McMartin, P. Lowry, 1974, The Biochemical journal.

Coriticotrophin-like intermediate lobe peptide--a new pituitary and tumour peptide.

C. McMartin, J. Ratcliffe, A. Scott, 1972, Journal of Endocrinology.

The fate of guanethidine in two hypertensive patients

C. McMartin, P. Humberstone, G. Sandler, 1970, Clinical pharmacology and therapeutics.

The isolation, identification and synthesis of two metabolites of guanethidine formed in pig and rabbit liver homogenates.

C. McMartin, R. Wade, F. B. Abramson, 1969, The Biochemical journal.

THE OXIDATION AND BROMINATION OF SOME PHENOTHIAZINE DERIVATIVES.

C. McMartin, H. Street, 2009, Acta pharmacologica et toxicologica.

Assessment of Docking Poses: Interactions-Based Accuracy Classification (IBAC) versus Crystal Structure Deviations

Anna Vulpetti, Pieter F. W. Stouten, Colin McMartin, 2004, J. Chem. Inf. Model..

QXP: Powerful, rapid computer algorithms for structure-based drug design

Colin McMartin, Regine S. Bohacek, R. Bohacek, 1997, J. Comput. Aided Mol. Des..

Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.

R S Bohacek, R. Bohacek, C. McMartin, 1992, Journal of medicinal chemistry.

A geometry force field which converts low‐resolution X‐ray models to structures with properties found at ultra high resolution

C. McMartin, 2012, Protein science : a publication of the Protein Society.

Flexible matching of test ligands to a 3D pharmacophore using a molecular superposition force field: Comparison of predicted and experimental conformations of inhibitors of three enzymes

Colin McMartin, Regine S. Bohacek, R. Bohacek, 1995, J. Comput. Aided Mol. Des..

A study of the action of peptides with corticotrophic activity on isolated adrenal cells.

C. McMartin, P. Lowry, 1972, The Journal of endocrinology.

Fate of corticotrophins in an isolated adrenal-cell bioassay and decrease of peptide breakdown by cell purification.

C. McMartin, G. Bullock, H. Bennett, 1974, The Biochemical journal.

Using structural information for the creative design of molecules

Colin McMartin, Regine S. Bohacek, R. Bohacek, 1999 .

On the degeneracy of the Hessian matrix

István Kolossváry, C. McMartin, I. Kolossváry, 1992 .

The mechanism of degradation of cyclo(-Asn-Phe-Phe-d-Trp-Lys-Thr-Phe-Gaba-) and the relative stabilities of this and other octapeptide somatostatin analogues in rat intestinal juice

G. E. Peters, C. McMartin, R. Wade, 1984, Regulatory Peptides.