Y. Gotoh

发表

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

K. Irie, E. Nishida, Kunihiro Matsumoto, 1998, The EMBO journal.

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

S. R. Datta, Xu Tao, M. Greenberg, 1997, Cell.

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3

Fuminori Tsuruta, N. Masuyama, Y. Gotoh, 2005, The Journal of cell biology.

JNK promotes Bax translocation to mitochondria through phosphorylation of 14‐3‐3 proteins

Fuminori Tsuruta, Yasunori Mori, Shigeomi Shimizu, 2004, The EMBO journal.

Use of RNA Interference-mediated Gene Silencing and Adenoviral Overexpression to Elucidate the Roles of AKT/Protein Kinase B Isoforms in Insulin Actions*

L. Cantley, N. Masuyama, Y. Gotoh, 2003, Journal of Biological Chemistry.

The Phosphatidylinositol 3-Kinase (PI3K)-Akt Pathway Suppresses Bax Translocation to Mitochondria*

Fuminori Tsuruta, N. Masuyama, Y. Gotoh, 2002, The Journal of Biological Chemistry.

Akt Enhances Mdm2-mediated Ubiquitination and Degradation of p53*

Toshiyuki Obata, N. Masuyama, Y. Gotoh, 2002, The Journal of Biological Chemistry.

Akt Inhibits the Orphan Nuclear Receptor Nur77 and T-cell Apoptosis*

N. Masuyama, Y. Gotoh, Y. Takahama, 2001, The Journal of Biological Chemistry.

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

Daniel Metzger, T. Kitamoto, S. Masushige, 1995, Science.

Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase.

K. Irie, K. Matsumoto, B. Errede, 1994, Science.

A Novel Regulatory Mechanism in the Mitogen-activated Protein (MAP) Kinase Cascade

E. Nishida, Y. Gotoh, M. Adachi, 1997, The Journal of Biological Chemistry.

The MAP kinase cascade is essential for diverse signal transduction pathways.

E. Nishida, Y. Gotoh, E Nishida, 1993, Trends in biochemical sciences.

Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells.

E. Nishida, Y. Gotoh, T. Yamashita, 1990, European journal of biochemistry.

Schizosaccharomyces pombe Spk1 is a tyrosine-phosphorylated protein functionally related to Xenopus mitogen-activated protein kinase

E. Nishida, M. Yamamoto, Y. Gotoh, 1993, Molecular and cellular biology.

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Minoru Takagi, Kohei Miyazono, K. Irie, 1997, Science.

Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction.

Y. Gotoh, J. Cooper, 1998, The Journal of biological chemistry.

IMP2 regulates differentiation potentials of mouse neocortical neural precursor cells

Y. Gotoh, Yuki Fujii, Y. Kishi, 2013, Genes to cells : devoted to molecular & cellular mechanisms.

Regulation of a major microtubule‐associated protein by MPF and MAP kinase.

E. Nishida, Y. Gotoh, K. Ohta, 1992, The EMBO journal.

Requirement for the MAP kinase kinase/MAP kinase cascade in Xenopus oocyte maturation.

E. Nishida, Y. Gotoh, H. Kosako, 1994, The EMBO journal.

Activation of Protein Kinase Cascades by Osmotic Shock (*)

H. Kawasaki, E. Nishida, Y. Gotoh, 1995, The Journal of Biological Chemistry.

Up‐regulation of HP1γ expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex

Y. Gotoh, S. Okabe, Y. Hirabayashi, 2015, Genes to cells : devoted to molecular & cellular mechanisms.

Microtubule severing by elongation factor 1 alpha.

E. Nishida, Y. Gotoh, A. Iwamatsu, 1994, Science.

Mitochondrial localization of the antiviral signaling adaptor IPS‐1 is important for its induction of caspase activation

Y. Gotoh, T. Okazaki, Maiko Higuchi, 2013, Genes to cells : devoted to molecular & cellular mechanisms.

Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes.

Y. Gotoh, T. Asano, H. Katagiri, 2003, Molecular endocrinology.

NEDDylation controls the target specificity of E2F1 and apoptosis induction

Y. Gotoh, I. Aoki, M. Higuchi, 2013, Oncogene.

Signaling pathways mediated by the mitogen‐activated protein (MAP) kinase kinase/MAP kinase cascade

E. Nishida, Y. Gotoh, S. Matsuda, 1994, Journal of leukocyte biology.

MKK6/3 and p38 MAPK Pathway Activation Is Not Necessary for Insulin-induced Glucose Uptake but Regulates Glucose Transporter Expression*

Y. Gotoh, T. Asano, M. Funaki, 2001, The Journal of Biological Chemistry.

Microtubule-severing activity in M phase.

E. Nishida, Y. Gotoh, N. Shiina, 1995, Trends in cell biology.

Multiple roles of the mitogen‐activated protein kinase kinase/mitogen‐activated protein kinase cascade in Xenopus laevis

E. Nishida, Y. Gotoh, H. Kosako, 1996, Development, growth & differentiation.

Roles of the MAP kinase cascade in vertebrates.

E. Nishida, Y. Gotoh, T. Moriguchi, 1996, Advances in pharmacology.

Regulation and function of the MAP kinase cascade in Xenopus oocytes

E. Nishida, Y. Gotoh, H. Kosako, 1994, Journal of Cell Science.

Microtubule nucleating activity of centrosomes in cell-free extracts from Xenopus eggs: involvement of phosphorylation and accumulation of pericentriolar material.

E. Nishida, Y. Gotoh, K. Ohta, 1993, Journal of cell science.

In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase

E. Nishida, Y. Gotoh, K. Ohta, 1991, Nature.

cDNA cloning of MAP kinase kinase reveals kinase cascade pathways in yeasts to vertebrates.

E. Nishida, Y. Gotoh, H. Kosako, 1993, The EMBO journal.

Lipid hydroperoxide‐induced apoptosis in human colonic CaCo‐2 cells is associated with an early loss of cellular redox balance

T. Aw, Y. Gotoh, C. Rhoads, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ras-dependent and Ras-independent activation pathways for the stress-activated-protein-kinase cascade.

H. Kawasaki, E. Nishida, S. Shimohama, 1996, European journal of biochemistry.

Oxidative stress induces insulin resistance by activating the nuclear factor-κB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

H. Aburatani, I. Komuro, Y. Gotoh, 2004, Diabetologia.

Sequential activation of MAP kinase activator, MAP kinases, and S6 peptide kinase in intact rat liver following insulin injection.

E. Nishida, Y. Gotoh, T. Kadowaki, 1992, The Journal of biological chemistry.

Okadaic acid activates microtubule-associated protein kinase in quiescent fibroblastic cells.

E. Nishida, Y. Gotoh, H. Sakai, 1990, European journal of biochemistry.

BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors

Y. Gotoh, Tomoyuki Watanabe, Daichi Kawaguchi, 2021, Scientific reports.

Akt1 promotes focal adhesion disassembly and cell motility through phosphorylation of FAK in growth factor-stimulated cells

Y. Gotoh, I. Aoki, S. Suetsugu, 2013, Journal of Cell Science.

Requirement for Mitogen-activated Protein Kinase in Cerebellar Long Term Depression*

H. Kawasaki, E. Nishida, S. Shimohama, 1999, The Journal of Biological Chemistry.

Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues.

E. Nishida, Y. Gotoh, T. Kadowaki, 1991, The Journal of biological chemistry.

Ezh1 regulates expression of Cpg15/Neuritin in mouse cortical neurons.

K. Sakimura, Y. Gotoh, M. Abe, 2021, Drug discoveries & therapeutics.

A novel homo‐oligomeric protein responsible for an MPF‐dependent microtubule‐severing activity.

E. Nishida, Y. Gotoh, N. Shiina, 1992, The EMBO journal.

Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2.

K. Irie, K. Matsumoto, M. Hagiwara, 1996, The Journal of biological chemistry.

Evidence for Multiple Activators for Stress-activated Protein Kinases/c-Jun Amino-terminal Kinases.

H. Kawasaki, E. Nishida, Y. Gotoh, 1995, The Journal of Biological Chemistry.

The MAP kinase cascade: its role in Xenopus oocytes, eggs and embryos.

E. Nishida, Y. Gotoh, Yukiko Gotoh, 1995, Progress in cell cycle research.

Phosphorylation of Xenopus mitogen-activated protein (MAP) kinase kinase by MAP kinase kinase kinase and MAP kinase.

E. Nishida, Y. Gotoh, S. Matsuda, 1993, The Journal of biological chemistry.

REGULATION OF THE CELL SURFACE EXPRESSION OF HUMAN BCRP/ABCG2 BY THE PHOSPHORYLATION STATE OF AKT IN POLARIZED CELLS

Y. Sugiyama, Y. Gotoh, Hiroshi Suzuki, 2005, Drug Metabolism and Disposition.

JNK phosphorylates synaptotagmin‐4 and enhances Ca2+‐evoked release

Y. Gotoh, Y. Mori, M. Fukuda, 2008, The EMBO journal.

Activation of a serine/threonine kinase that phosphorylates microtubule-associated protein 1B in vitro by growth factors and phorbol esters in quiescent rat fibroblastic cells.

E. Nishida, Y. Gotoh, M. Inagaki, 1990, European journal of biochemistry.

Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase.

H. Aburatani, I. Komuro, Y. Gotoh, 2004, Diabetologia.

Activation mechanism and function of the MAP kinase cascade

E. Nishida, Y. Gotoh, 1995, Molecular reproduction and development.

Mitogen-Activated Protein Kinase

T. Toda, E. Nishida, Y. Gotoh, 2020, Definitions.

Characterization of recombinant Xenopus MAP kinase kinases mutated at potential phosphorylation sites.

E. Nishida, Y. Gotoh, S. Hattori, 1994, Oncogene.

Schizosaccharomyces pombeSpklisaTyrosine- Phosphorylated Protein Functionally Related toXenopus Mitogen-Activated

Y. Gotoh, 1993 .

Endfoot regrowth for neural stem cell renewal

Y. Gotoh, Masafumi Tsuboi, 2019, Nature Cell Biology.

The PI3K‐Akt pathway promotes microtubule stabilization in migrating fibroblasts

N. Masuyama, Y. Gotoh, T. Asakura, 2007, Genes to cells : devoted to molecular & cellular mechanisms.

Neurexin nanoclusters: A novel structure at presynaptic terminals

Y. Gotoh, Daichi Kawaguchi, 2019, The Journal of cell biology.

A mitogen-activated protein (MAP) kinase activating factor in mammalian mitogen-stimulated cells is homologous to Xenopus M phase MAP kinase activator.

E. Nishida, Y. Gotoh, K. Shirakabe, 1992, The Journal of biological chemistry.

Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system.

E. Nishida, Y. Gotoh, S. Hattori, 1992, The Journal of biological chemistry.

Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities.

M. Kano, Naofumi Uesaka, Y. Gotoh, 2020, Cell reports.

Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module

R. Kageyama, Y. Gotoh, I. Imayoshi, 2021, Nature Communications.

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

Yutaka Suzuki, Y. Gotoh, Y. Fukazawa, 2018, Nature Communications.

Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex

S. Akira, K. Takeda, N. Masuyama, 2006, Development.

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

E. Nishida, Y. Gotoh, M. Fukuda, 1997, The EMBO journal.

MST1‐JNK promotes apoptosis via caspase‐dependent and independent pathways

N. Masuyama, Y. Gotoh, J. Graves, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction*

Y. Gotoh, J. Cooper, 1998, The Journal of Biological Chemistry.

Initiation of Xenopus Oocyte Maturation by Activation of the Mitogen-activated Protein Kinase Cascade (*)

E. Nishida, N. Masuyama, Y. Gotoh, 1995, The Journal of Biological Chemistry.

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction.

K. Irie, E. Nishida, H. Shibuya, 1996, Science.

Mitogen-activated-protein-kinase-catalyzed phosphorylation of microtubule-associated proteins, microtubule-associated protein 2 and microtubule-associated protein 4, induces an alteration in their function.

E. Nishida, Y. Gotoh, K. Ohta, 1992, European journal of biochemistry.

Epigenetic control of neural precursor cell fate during development

Y. Gotoh, Y. Hirabayashi, 2010, Nature Reviews Neuroscience.

Zbtb20 promotes astrocytogenesis during neocortical development

Toru Ogata, Yasuhiro Sawada, Y. Gotoh, 2016, Nature Communications.

Activation and Involvement of p38 Mitogen-activated Protein Kinase in Glutamate-induced Apoptosis in Rat Cerebellar Granule Cells*

E. Nishida, S. Shimohama, T. Hirano, 1997, The Journal of Biological Chemistry.

Plag1 regulates neuronal gene expression and neuronal differentiation of neocortical neural progenitor cells

Y. Gotoh, H. Sakai, Yuki Fujii, 2019, Genes to cells : devoted to molecular & cellular mechanisms.

Chromatin regulators of neural development

Y. Gotoh, K. Tyssowski, Y. Kishi, 2014, Neuroscience.

HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells

Y. Gotoh, Y. Hirabayashi, Yuki Fujii, 2012, Nature Neuroscience.

Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis.

M. Nakafuku, N. Masuyama, Y. Gotoh, 2004, Developmental biology.

Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon

Y. Gotoh, K. Hozumi, T. Yoshimatsu, 2008, Development.

Transcriptional coupling of neuronal fate commitment and the onset of migration

Y. Gotoh, K. Tyssowski, Kelsey M. Tyssowski, 2013, Current Opinion in Neurobiology.

Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling

M. Nakafuku, N. Masuyama, Y. Gotoh, 2004, Nature Cell Biology.

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

Yutaka Suzuki, Y. Gotoh, Y. Fukazawa, 2018, Nature Communications.

A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development

Y. Gotoh, Masahiro Onoguchi, H. Koseki, 2012, Proceedings of the National Academy of Sciences.

Tcf3 Represses Wnt–β-Catenin Signaling and Maintains Neural Stem Cell Population during Neocortical Development

Yusuke Hirabayashi, Y. Gotoh, Y. Hirabayashi, 2014, PloS one.

Stage-dependent fate determination of neural precursor cells in mouse forebrain

Y. Gotoh, Y. Hirabayashi, 2005, Neuroscience Research.

The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells

Tetsu Akiyama, Yusuke Hirabayashi, Kazunori Nakajima, 2004, Development.

Cytoplasmic Localization of Mitogen-activated Protein Kinase Kinase Directed by Its NH2-terminal, Leucine-rich Short Amino Acid Sequence, Which Acts as a Nuclear Export Signal*

E. Nishida, Y. Gotoh, M. Fukuda, 1996, The Journal of Biological Chemistry.

Diverse gene regulatory mechanisms mediated by Polycomb group proteins during neural development

Y. Gotoh, Y. Hirabayashi, Masafumi Tsuboi, 2019, Current Opinion in Neurobiology.

Regulation of Chromatin Structure During Neural Development

Y. Gotoh, Y. Kishi, 2018, Front. Neurosci..

Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex.

Y. Gotoh, H. Koseki, Y. Hirabayashi, 2018, Developmental cell.

Caspase‐mediated activation and induction of apoptosis by the mammalian Ste20‐like kinase Mst1

E. Krebs, Y. Gotoh, E. Clark, 1998, The EMBO journal.

A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C

Y. Watanabe, K. Irie, K. Matsumoto, 1993, Molecular and cellular biology.

Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation

N. Masuyama, Y. Gotoh, J. Graves, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Activation of the c-Jun N-Terminal Kinase Pathway by MST1 Is Essential and Sufficient for the Induction of Chromatin Condensation during Apoptosis

Toshiaki Katada, Seiji Ura, T. Katada, 2007, Molecular and Cellular Biology.

Both Phosphorylation and Caspase-mediated Cleavage Contribute to Regulation of the Ste20-like Protein Kinase Mst1 during CD95/Fas-induced Apoptosis*

E. Krebs, Y. Gotoh, E. Clark, 2001, The Journal of Biological Chemistry.

Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition

M. Vidal, Y. Gotoh, Tetsuro Toyoda, 2009, Neuron.

A novel SAPK/JNK kinase, MKK7, stimulated by TNFα and cellular stresses

E. Nishida, N. Masuyama, Y. Gotoh, 1997, The EMBO journal.

TAK1 Mediates the Ceramide Signaling to Stress-activated Protein Kinase/c-Jun N-terminal Kinase*

K. Irie, E. Nishida, Kunihiro Matsumoto, 1997, The Journal of Biological Chemistry.

Purification and Identification of a Major Activator for p38 from Osmotically Shocked Cells

K. Irie, M. Hagiwara, E. Nishida, 1996, The Journal of Biological Chemistry.

A Novel Kinase Cascade Mediated by Mitogen-activated Protein Kinase Kinase 6 and MKK3*

K. Irie, M. Hagiwara, E. Nishida, 1996, The Journal of Biological Chemistry.

TAB1: An Activator of the TAK1 MAPKKK in TGF-β Signal Transduction

K. Irie, E. Nishida, Kunihiro Matsumoto, 1996, Science.

Changes of chromosomal architecture before establishment of chromosome territories revealed by recurrence plot reconstruction

Yoshito Hirata, Y. Gotoh, Hiroki Sugishita, 2021, bioRxiv.

α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2

W. Yung, Y. Gotoh, N. Ip, 2011, Nature Neuroscience.

Development and Stem Cells Research Article

T. Kodama, Y. Gotoh, M. Taketo, 2022 .

Epidermal Growth Factor Signaling Mediated by Grb2 Associated Binder1 Is Required for the Spatiotemporally Regulated Proliferation of Olig2‐Expressing Progenitors in the Embryonic Spinal Cord

T. Shimazaki, H. Okano, T. Hirano, 2007, Stem cells.

PDK1–Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex

Y. Gotoh, Koji Oishi, K. Nakajima, 2016, Proceedings of the National Academy of Sciences.

The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway

G. Superti-Furga, T. Toda, E. Nishida, 1996, Molecular and cellular biology.

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

R. Jessberger, Y. Gotoh, N. Mochizuki, 2002, Nature.

Adenosine A 2 A Receptor Facilitates Calcium-Dependent Protein Secretion through the Activation of Protein Kinase A and Phosphatidylinositol-3 Kinase in PC 12 Cells

N. Masuyama, Y. Gotoh, Y. Mori, 2005 .

Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade

Kunihiro Matsumoto, H. Shibuya, Y. Gotoh, 2003, Nature Cell Biology.

Transfected platelet-activating factor receptor activates mitogen-activated protein (MAP) kinase and MAP kinase kinase in Chinese hamster ovary cells.

E. Nishida, Y. Gotoh, T. Takano, 1994, The Journal of biological chemistry.

Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells

K. Nakayama, Y. Gotoh, Tomoyuki Watanabe, 2015, Nature Neuroscience.

β‐Catenin Signaling Promotes Proliferation of Progenitor Cells in the Adult Mouse Subventricular Zone

H. Okano, A. Álvarez-Buylla, K. Sawamoto, 2007, Stem cells.

Area-Specific Regulation of Quiescent Neural Stem Cells by Notch3 in the Adult Mouse Subependymal Zone

Y. Gotoh, B. Kuebrich, M. Yamaguchi, 2017, The Journal of Neuroscience.

Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis

Y. Gotoh, K. Hozumi, Daichi Kawaguchi, 2013, Nature Communications.

Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells

N. Masuyama, Y. Gotoh, A. Suzuki, 2001, Current Biology.

Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition–like mechanism

Y. Gotoh, Tetsuro Toyoda, T. Endo, 2013, Nature Neuroscience.

Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1

H. Okano, F. Guillemot, Y. Gotoh, 2009, Proceedings of the National Academy of Sciences.

Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells.

K. Shinozaki, E. Nishida, K. Yamaguchi-Shinozaki, 1994, The Plant journal : for cell and molecular biology.

Isolation of genetically manipulated neural progenitors and immature neurons from embryonic mouse neocortex by FACS

Y. Gotoh, Y. Kishi, 2021, STAR protocols.

Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway

Y. Gotoh, M. Koike, Y. Fujiki, 2019, Journal of Cell Science.

Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent pathway of apoptosis

Y. Gotoh, M. Koike, Y. Fujiki, 2018, bioRxiv.

Molecular mechanisms of neuronal survival; Roles of kinases in ischemic cell death

Y. Gotoh, 2002 .

Transcriptional activation of mouse major satellite regions during neuronal differentiation.

Y. Gotoh, Y. Kishi, Shigeki Kondo, 2012, Cell structure and function.

Mechanisms that regulate the number of neurons during mouse neocortical development

Y. Gotoh, A. Kawaguchi, T. Miyata, 2010, Current Opinion in Neurobiology.

Xenopus MAP kinase activator is a serine/threonine/tyrosine kinase activated by threonine phosphorylation.

E. Nishida, Y. Gotoh, S. Matsuda, 1992, The EMBO journal.

Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade.

T. Akiyama, E. Nishida, Y. Gotoh, 1992, The EMBO journal.

A role for Hmga2 in the early-stage transition of neural stem-progenitor cell properties during mouse neocortical development

Y. Gotoh, H. Koseki, Y. Hirabayashi, 2020 .

NUDT21 links mitochondrial IPS-1 to RLR-containing stress granules and activates host antiviral defense

Y. Gotoh, T. Natsume, S. Iemura, 2020, bioRxiv.

The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response

T. Taniguchi, M. Kiso, Y. Kawaoka, 2015, Science Signaling.

Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade.

E. Nishida, Y. Gotoh, H. Bito, 1994, The Journal of biological chemistry.

MAP Kinase Is Required for the Spindle Assembly Checkpoint but Is Dispensable for the Normal M Phase Entry and Exit in Xenopus Egg Cell Cycle Extracts

E. Nishida, Y. Gotoh, K. Takenaka, 1997, The Journal of cell biology.

β-Amyloid Induces Neuronal Apoptosis Via a Mechanism that Involves the c-Jun N-Terminal Kinase Pathway and the Induction of Fas Ligand

M. Greenberg, R. Flavell, Y. Gotoh, 2001, The Journal of Neuroscience.

The Cyclin-dependent Kinase Inhibitors p57 and p27 Regulate Neuronal Migration in the Developing Mouse Neocortex*

K. Nakayama, N. Masuyama, Y. Gotoh, 2007, Journal of Biological Chemistry.

Summary The Wnt / β-catenin pathway directs neuronal differentiation of cortical neural precursor cells

Tetsu Akiyama, Yusuke Hirabayashi, Kazunori Nakajima, 2004 .

The Sox-2 Regulatory Regions Display Their Activities in Two Distinct Types of Multipotent Stem Cells

A. Iwama, H. Nakauchi, N. Masuyama, 2004, Molecular and Cellular Biology.

Purification and Identification of a Major Activator for p38 from Osmotically Shocked Cells ACTIVATION OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 BY OSMOTIC SHOCK, TUMOR NECROSIS FACTOR-a, AND H2O2*

K. Irie, M. Hagiwara, E. Nishida, 1996 .

A simple method for gene expression in endo- and ectodermal cells in mouse embryos before neural tube closure

Yutaka Suzuki, Y. Gotoh, H. Koseki, 2020, bioRxiv.

Suppression of Nerve Growth Factor-induced Neuronal Differentiation of PC12 Cells

E. Nishida, Y. Gotoh, S. Matsuda, 1996, The Journal of Biological Chemistry.

Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development

Y. Gotoh, Tomoyuki Watanabe, Daichi Kawaguchi, 2020, Scientific Reports.

Role of the imprinted allele of the p57Kip2 gene in mouse neocortical development

Y. Gotoh, Tomoyuki Watanabe, Daichi Kawaguchi, 2019, bioRxiv.

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade.

Kunihiro Matsumoto, H. Shibuya, Y. Gotoh, 2003, Nature cell biology.

Maintenance of neural stem‐progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon

Yutaka Suzuki, Y. Ishihama, Y. Gotoh, 2021, Stem cells.

Activation of two isoforms of mitogen-activated protein kinase kinase in response to epidermal growth factor and nerve growth factor.

E. Nishida, Y. Gotoh, T. Moriguchi, 1995, European journal of biochemistry.

protein kinase C . homolog ( Mpk 1 p ) mediates signalling by A yeast mitogen-activated protein kinase

Y. Watanabe, K. Irie, D. E. Levin, 2022 .

The phosphatidylinositol‐3 kinase (PI3K)‐Akt pathway suppresses neurite branch formation in NGF‐treated PC12 cells

N. Masuyama, Y. Gotoh, Maiko Higuchi, 2003, Genes to cells : devoted to molecular & cellular mechanisms.

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.

H. Kawasaki, K. Suzuki, E. Nishida, 1991, The EMBO journal.

Analysis of histone modifications in mouse neocortical neural progenitor-stem cells at various developmental stages

Y. Gotoh, Masafumi Tsuboi, 2021, STAR protocols.

PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development

Y. Gotoh, Y. Hirabayashi, K. Watatani, 2012, Genes to cells : devoted to molecular & cellular mechanisms.

The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development

M. Vidal, Y. Gotoh, H. Koseki, 2014, Development.

Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation.

Y. Yazaki, E. Nishida, Y. Gotoh, 1994, The Journal of biological chemistry.

Mitogen-activated protein kinase and cytoskeleton in mitogenic signal transduction.

E. Nishida, Y. Gotoh, 1992, International review of cytology.

Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation.

Y. Gotoh, M. Matsuda, H. Yoshizaki, 2006, Molecular biology of the cell.

Involvement of the MAP kinase cascade in Xenopus mesoderm induction.

E. Nishida, N. Masuyama, Y. Gotoh, 1995, The EMBO journal.

The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

Y. Gotoh, H. Koseki, Hiroki Sugishita, 2019, Nature Communications.

p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis

Akinobu Matsumoto, K. Nakayama, Y. Gotoh, 2013, The EMBO journal.

Mitogen-activated protein kinase kinase is required for the mos-induced metaphase arrest.

E. Nishida, Y. Gotoh, H. Kosako, 1994, The Journal of biological chemistry.

Analysis of the Ras p21/mitogen-activated protein kinase signaling in vitro and in Xenopus oocytes.

E. Nishida, Y. Gotoh, S. Hattori, 1994, The Journal of biological chemistry.

Scaffolding function of PAK in the PDK1–Akt pathway

Y. Gotoh, Yukiko Gotoh, Chikako Kikuchi, 2008, Nature Cell Biology.

Differing Roles of Akt and Serum- and Glucocorticoid-regulated Kinase in Glucose Metabolism, DNA Synthesis, and Oncogenic Activity*

Y. Gotoh, T. Asano, H. Katagiri, 2003, Journal of Biological Chemistry.

Induction of neurite outgrowth by MAP kinase in PC12 cells.

E. Nishida, Y. Gotoh, S. Hattori, 1995, Oncogene.

Signals for mesoderm induction. Roles of fibroblast growth factor (FGF)/mitogen-activated protein kinase (MAPK) pathway.

E. Nishida, Y. Gotoh, 1996, Biochimica et biophysica acta.

Retraction Note: Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade

Kunihiro Matsumoto, H. Shibuya, Y. Gotoh, 2014, Nature Cell Biology.

TIMP3 promotes the maintenance of neural stem-progenitor cells in the mouse subventricular zone

Y. Gotoh, O. Yasuda, Lingyan Fang, 2023, Frontiers in Neuroscience.

High Mobility Group Nucleosome‐Binding Family Proteins Promote Astrocyte Differentiation of Neural Precursor Cells

Y. Gotoh, T. Ogata, Y. Kishi, 2014, Stem cells.

Adenosine A2A receptor facilitates calcium-dependent protein secretion through the activation of protein kinase A and phosphatidylinositol-3 kinase in PC12 cells.

N. Masuyama, Y. Gotoh, Y. Mori, 2004, Cell structure and function.

Mineralization induced by beta-glycerophosphate in cultures leads to a marked increase in collagenase synthesis by mouse osteogenic MC3T3-E1 cells under subsequent stimulation with heparin.

Y. Gotoh, S. Sakamoto, M. Sakamoto, 1989, Biochemical and biophysical research communications.

Mitogen-Activated Protein Kinase

T. Toda, E. Nishida, Y. Gotoh, 2022 .

Schizosaccharomyces pombe Spk1 is a tyrosine-phosphorylated protein functionally related to Xenopus mitogen-activated protein kinase.

T. Toda, E. Nishida, Y. Gotoh, 1993, Molecular and cellular biology.

Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32

F. Tashiro, Y. Gotoh, C. Kitanaka, 2004, Cell Death and Differentiation.

Mitochondrial localization of the antiviral signaling adaptor IPS‐1 is important for its induction of caspase activation

Y. Gotoh, Maiko Higuchi, Tomohiko Okazaki, 2013, Genes to cells : devoted to molecular & cellular mechanisms.

PDK1–Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex

Y. Gotoh, Koji Oishi, K. Nakajima, 2016, Proceedings of the National Academy of Sciences.

An Unexpected Calm: Mfge8 Controls Stem Cell Quiescence and Maintenance.

Y. Gotoh, Tomohiko Okazaki, 2018, Cell stem cell.

Mitogen-Activated Protein Kinase

T. Toda, E. Nishida, Y. Gotoh, 2022 .

The PI 3 K-Akt pathway suppresses Bax translocation to mitochondria

Y. Gotoh, Fuminori Tsuruta, Norihisa Masuyama, 2002 .

Changes of chromosomal architecture before establishment of chromosome territories revealed by recurrence plot reconstruction

Yoshito Hirata, Y. Gotoh, Hiroki Sugishita, 2021, bioRxiv.