D. Altschuh

发表

Coordinated amino acid changes in homologous protein families.

K. Nagai, D. Altschuh, T. Vernet, 1988, Protein engineering.

Correlation of co-ordinated amino acid substitutions with function in viruses related to tobacco mosaic virus.

A. Lesk, A. Klug, D. Altschuh, 1987, Journal of molecular biology.

Studying Molecular Interactions, a First Step Toward Cellular and Molecular Bioengineering

D. Altschuh, P. Bongrand, 2008 .

Functional aspects of co‐variant surface charges in an antibody fragment

D. Altschuh, N. Hugo, V. Lafont, 2002, Protein science : a publication of the Protein Society.

Antibody Binding Selectivity: Alternative Sets of Antigen Residues Entail High-Affinity Recognition

D. Altschuh, T. Vernet, Y. Nominé, 2015, PloS one.

Correlation between segmental mobility and the location of antigenic determinants in proteins

D. Moras, A. Klug, E. Westhof, 1984, Nature.

A peptide-based fluorescent ratiometric sensor for quantitative detection of proteins.

D. Altschuh, Y. Mély, L. Choulier, 2010, Analytical biochemistry.

Fluorescence sensing of intermolecular interactions and development of direct molecular biosensors

D. Altschuh, A. Demchenko, Sule Oncul, 2006, Journal of molecular recognition : JMR.

Comparative sensitivity of different ELISA procedures for detecting monoclonal antibodies

D. Altschuh, M. V. Regenmortel, J. Briand, 1984 .

Protein–protein recognition and interaction hot spots in an antigen–antibody complex: Free energy decomposition identifies “efficient amino acids”

Annick Dejaegere, Roland H Stote, R. Stote, 2007, Proteins.

Correlation of co-ordinated amino acid changes at the two-domain interface of cysteine proteases with protein stability.

D Altschuh, T Vernet, D. Tessier, 1992, Journal of molecular biology.

Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions.

D. Altschuh, A. Davranche, F. Klein, 2011, Human molecular genetics.

Conformational polymorphism of cyclosporin A.

K Wüthrich, D Altschuh, K. Wüthrich, 1994, Structure.

Cutting Edge: Monovalency of CD28 Maintains the Antigen Dependence of T Cell Costimulatory Responses1

D. Altschuh, G. Zeder‐Lutz, T. Hünig, 2006, The Journal of Immunology.

Determination of kinetic constants for the interaction between a monoclonal antibody and peptides using surface plasmon resonance.

D. Altschuh, E. Weiss, M. V. Van Regenmortel, 1992, Biochemistry.

9 Surface Methods

S. Ricard-Blum, D. Altschuh, P. Schaaf, 2010 .

A conformation of cyclosporin A in aqueous environment revealed by the X-ray structure of a cyclosporin-Fab complex.

D Altschuh, D. Altschuh, B. Rees, 1992, Science.

Crystallization and preliminary X-ray investigation of a complex between a Fab fragment and its antigen, cyclosporin.

D. Altschuh, M. V. Van Regenmortel, J. Thierry, 1989, Journal of molecular biology.

Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes

D. Altschuh, Y. Nominé, C. M. Lombardo, 2018, Oncotarget.

Surface plasmon resonance analysis of the binding mechanism of pharmacological and peptidic inhibitors to human somatic angiotensin I-converting enzyme.

L. Miclo, D. Altschuh, C. Corbier, 2013, Biochemistry.

Interaction between viruses and monoclonal antibodies studied by surface plasmon resonance.

D. Altschuh, M. V. Van Regenmortel, M. Dubs, 1992, Immunology letters.

Mapping of viral epitopes with conformationally specific monoclonal antibodies using biosensor technology.

D. Altschuh, M. V. Van Regenmortel, M. Dubs, 1992, Journal of chromatography.

A peptide-based, ratiometric biosensor construct for direct fluorescence detection of a protein analyte.

D. Altschuh, Y. Mély, A. Demchenko, 2008, Bioconjugate chemistry.

Kinetic analysis of the effect on Fab binding of identical substitutions in a peptide and its parent protein.

D. Altschuh, T. Vernet, L. Choulier, 1999, Biochemistry.

High-Risk Mucosal Human Papillomavirus 16 (HPV16) E6 Protein and Cutaneous HPV5 and HPV8 E6 Proteins Employ Distinct Strategies To Interfere with Interferon Regulatory Factor 3-Mediated Beta Interferon Expression

P. Peixoto, D. Altschuh, Y. Chebaro, 2022, Journal of virology.

Comparative properties of two peptide-antibody interactions as deduced from epitope delineation.

D. Laune, D. Altschuh, E. Weiss, 2002, Journal of immunological methods.

Functional mapping of conserved, surface‐exposed charges of antibody variable domains

D. Altschuh, T. Vernet, N. Hugo, 2002, Journal of molecular recognition : JMR.

Uses of biosensors in the study of viral antigens.

D. Altschuh, M. V. Van Regenmortel, P. Richalet-Sécordel, 1997, Immunological investigations.

BIACORE data processing: an evaluation of the global fitting procedure.

M B Khalifa, L Choulier, H Lortat-Jacob, 2001, Analytical biochemistry.

Cooperative effects of mutations in a recombinant Fab on the kinetics of antigen binding.

D. Altschuh, E. Weiss, M. V. Van Regenmortel, 1997, Molecular immunology.

Visualization by electron microscopy of the location of tobacco mosaic virus epitopes reacting with monoclonal antibodies in enzyme immunoassay.

D. Altschuh, E. Weiss, M. V. Van Regenmortel, 1988, Virology.

Designing antibodies for the inhibition of gastrin activity in tumoral cell lines

D. Altschuh, R. Meloen, J. Casal, 2008, International journal of cancer.

Determination of IgG and IgM levels in serum by rocket immunoelectrophoresis using yolk antibodies from immunized chickens.

D. Altschuh, G. Hennache, M. V. van Regenmortel, 1984, Journal of immunological methods.

Interaction of cyclosporin A and two cyclosporin analogs with cyclophilin: relationship between structure and binding.

D. Altschuh, G. Zeder‐Lutz, R. Wenger, 1994, Journal of chromatography. B, Biomedical applications.

Role of Conformation on the Antigenic Determinants of Tobacco Mosaic Virus Protein

D. Altschuh, M. V. Regenmortel, J. Briand, 1983 .

Tobacco mosaic virus: a model antigen to study virus-antibody interactions.

D. Altschuh, M. V. Regenmortel, G. Zeder‐Lutz, 1993, Biochimie.

Small‐Molecule Negative Modulators of Adrenomedullin: Design, Synthesis, and 3D‐QSAR Study

D. Altschuh, L. Choulier, Virginia Roldós, 2008, ChemMedChem.

Novel short peptides isolated from phage display library inhibit vascular endothelial growth factor activity

D. Altschuh, B. Salih, G. Zeder‐Lutz, 2007, Molecular biotechnology.

Deciphering complex protein interaction kinetics using Interaction Map.

D. Altschuh, K. Andersson, L. Choulier, 2012, Biochemical and biophysical research communications.

VL position 34 is a key determinant for the engineering of stable antibodies with fast dissociation rates.

D Altschuh, T Vernet, D. Altschuh, 2003, Protein engineering.

Covariance analysis of protein families: The case of the variable domains of antibodies

D. Altschuh, N. Hugo, V. Lafont, 2000, Proteins.

Interaction of cyclosporin A with an Fab fragment or cyclophilin Affinity measurements and time‐dependent changes in binding

D. Altschuh, G. Zeder‐Lutz, R. Wenger, 1993, FEBS letters.

Biosensor Characterization of Structure–Function Relationships in Viral Proteins

L Choulier, D Altschuh, D. Altschuh, 2004 .

Principles of antigens antibody recognition

D. Altschuh, M. V. Regenmortel, M. Regenmortel, 2002 .

Predicting the kinetics of peptide–antibody interactions using a multivariate experimental design of sequence and chemical space

L Choulier, D Altschuh, Markku D. Hämäläinen, 2001, Journal of molecular recognition : JMR.

Measurement of antigen–antibody interactions with biosensors

D. Altschuh, M. V. Regenmortel, G. Zeder‐Lutz, 1998, Journal of molecular recognition : JMR.

Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient.

Annalisa Pastore, Jean-Louis Mandel, A. Pastore, 2007, Journal of molecular biology.

Pepper mild mottle virus, a tobamovirus infecting pepper cultivars in Sicily

D. Altschuh, M. V. Regenmortel, C. Wetter, 1984 .

Cyclosporin A as a model antigen: immunochemical and structural studies

D. Altschuh, 2002, Journal of molecular recognition : JMR.

Analysis of cyclosporin interactions with antibodies and cyclophilin using the BIAcore.

D. Altschuh, G. Zeder‐Lutz, M. V. van Regenmortel, 1995, Journal of immunological methods.

Modulation of the enzymatic activity of papain by interdomain residues remote from the active site.

D. Tessier, D. Altschuh, T. Vernet, 1994, Protein Engineering.

Non‐Reciprocity of the Serological Relationship Between the Italian III Strain and Other Strains of Tobacco Mild Green Mosaic Virus

D. Altschuh, C. Wetter, 1987 .

Sequence and Antigenic Activity of the Region 93 to 113 of the Coat Protein of Strain U2 of Tobacco Mosaic Virus

D. Altschuh, M. V. Regenmortel, J. Reinbolt, 1981 .

Structure-activity relationships for the interaction between cyclosporin A derivatives and the Fab fragment of a monoclonal antibody.

D. Altschuh, G. Zeder‐Lutz, R. Wenger, 1994, Molecular immunology.

Kinetic analysis of the interactions of human papillomavirus E6 oncoproteins with the ubiquitin ligase E6AP using surface plasmon resonance.

Gilles Travé, D. Altschuh, Y. Nominé, 2005, Journal of molecular biology.

Evolution of Hemoglobin as Studied by Protein Engineering and X-Ray Crystallography

K. Nagai, D. Altschuh, J. Tame, 1988 .

Thioether Analogues of Disulfide‐Bridged Cyclic Peptides Targeting Death Receptor 5: Conformational Analysis, Dimerisation and Consequences for Receptor Activation

H. Gronemeyer, D. Altschuh, C. Smulski, 2015, Chembiochem : a European journal of chemical biology.

QSAR studies applied to the prediction of antigen-antibody interaction kinetics as measured by BIACORE.

Magnus Malmqvist, Karl Andersson, Laurence Choulier, 2002, Protein engineering.

Novel surface-based methodologies for investigating GH11 xylanase-lignin derivative interactions.

D. Altschuh, B. Chabbert, C. Rémond, 2013, The Analyst.

Knowledge-based design of reagentless fluorescent biosensors from recombinant antibodies.

Hugues Bedouelle, Laurent Belkadi, Patrick England, 2002, Journal of molecular biology.

Monoclonal antipeptide antibodies: affinity and kinetic rate constants measured for the peptide and the cognate protein using a biosensor technology.

D. Altschuh, G. Zeder‐Lutz, É. Trifilieff, 1993, Molecular immunology.

Spot peptide arrays and SPR measurements: throughput and quantification in antibody selectivity studies

D. Altschuh, T. Vernet, Y. Nominé, 2015, Journal of molecular recognition : JMR.

Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity

D. Altschuh, A. Griffioen, R. Meloen, 2016, Proceedings of the National Academy of Sciences.

Effects on interaction kinetics of mutations at the VH–VL interface of Fabs depend on the structural context

Laurence Choulier, D. Altschuh, T. Vernet, 2000, Journal of molecular recognition : JMR.

Functional mapping of conserved residues located at the VL and VH domain interface of a Fab.

D Altschuh, T Vernet, D. Altschuh, 1996, Journal of molecular biology.

Delineation of a linear epitope by multiple peptide synthesis and phage display.

L Choulier, D Altschuh, D. Laune, 2001, Journal of immunological methods.

Comparative sensitivity of different ELISA methods for detecting monoclonal antibodies to viruses.

D. Altschuh, J. Briand, M. V. van Regenmortel, 1984, Developments in biological standardization.

Binding of CDR‐derived peptides is mechanistically different from that of high‐affinity parental antibodies

J. Desmet, D. Altschuh, R. Meloen, 2010, Journal of molecular recognition : JMR.

A Combinatorial Approach for the Design of Complementarity-determining Region-derived Peptidomimetics with in Vitro Anti-tumoral Activity*

J. Desmet, D. Altschuh, R. Meloen, 2009, The Journal of Biological Chemistry.

A fast mutagenesis procedure to recover soluble and functional scFvs containing amber stop codons from synthetic and semisynthetic antibody libraries.

Rodrigo Barderas, D. Altschuh, R. Meloen, 2006, Journal of immunological methods.

Analysis of Viral Antigens Using Biosensor Technology

Jean-Luc Pellequer, M.H.V. Van Regenmortel, D. Altschuh, 1994 .

Epitope analysis using kinetic measurements of antibody binding to synthetic peptides presenting single amino acid substitutions

D. Altschuh, S. Denery-Papini, G. Tribbick, 1993, Journal of molecular recognition : JMR.

Chemical library screening using a SPR-based inhibition in solution assay: simulations and experimental validation.

D. Altschuh, Y. Nominé, S. Charbonnier, 2013, Analytical chemistry.

SPR identification of mild elution conditions for affinity purification of E6 oncoprotein, using a multivariate experimental design

D. Altschuh, D. Desplancq, L. Choulier, 2008, Journal of molecular recognition : JMR.

Immunochemical studies of tobacco mosaic virus--VI. Attempts to localize viral epitopes with monoclonal antibodies.

D. Altschuh, M. V. Regenmortel, Z. A. Moudallal, 1985, Molecular immunology.

Immunochemical studies of tobacco mosaic virus--V. Localization of four epitopes in the protein subunit by inhibition tests with synthetic peptides and cleavage peptides from three strains.

D. Altschuh, J. Reinbolt, D. Hartman, 1983, Molecular immunology.

Localization of antigenic determinants of a viral protein by inhibition of enzyme-linked immunosorbent assay (ELISA) with tryptic peptides.

D. Altschuh, M. Regenmortel, 1982, Journal of immunological methods.

Influence of local structure on the location of antigenic determinants in tobacco mosaic virus protein.

A. Klug, D. Altschuh, M. V. van Regenmortel, 1986, Ciba Foundation symposium.

Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders.

Laurence Choulier, Alberto Podjarny, D. Altschuh, 2012, Analytical biochemistry.

Comparative interaction kinetics of two recombinant fabs and of the corresponding antibodies directed to the coat protein of tobacco mosaic virus

D. Altschuh, E. Weiss, N. Rauffer‐Bruyère, 1996, Journal of molecular recognition : JMR.