P. Traber

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The effect of student- and teacher-centred small-group learning in medical school on knowledge acquisition, retention and application

J. Kolars, L. Gruppen, P. Traber, 1997 .

Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity.

P. Traber, E. Rings, F. Boudreau, 2001, Gastroenterology.

Surviving Hurricane Katrina: reconstructing the educational enterprise of Tulane University School of Medicine.

P. Whelton, P. Traber, R. Markert, 2007, Academic medicine : journal of the Association of American Medical Colleges.

A homeodomain protein related to caudal regulates intestine-specific gene transcription

P. Traber, Lin Chen, J. Taylor, 1994, Molecular and cellular biology.

cis-Acting elements and transcription factors involved in the intestinal specific expression of the rat calbindin-D9K gene: binding of the intestine-specific transcription factor Cdx-2 to the TATA box.

P. Traber, E. Suh, M. Raymondjean, 1996, European journal of biochemistry.

Brain Edema in Experimental Fulminant Hepatic Failure

P. Traber, A. Blei, 1989 .

Effect of body temperature on brain edema and encephalopathy in the rat after hepatic devascularization.

D. Ganger, P. Traber, A. Blei, 1989, Gastroenterology.

Brain edema in rabbits with galactosamine-induced fulminant hepatitis. Regional differences and effects on intracranial pressure.

D. Ganger, P. Traber, A. Blei, 1986, Gastroenterology.

Brain edema in rabbits with galactosamine-induced fulminant hepatitis. Regional differences and effects on intracranial pressure.

D. Ganger, P. Traber, A. Blei, 1986, Gastroenterology.

Galectins in Disease and Potential Therapeutic Approaches

P. Traber, A. Klyosov, 2012 .

Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific.

P. Traber, J. Taylor, E. Suh, 1997, Nucleic acids research.

Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters.

P. Traber, J. Taylor, E. Suh, 1997, DNA and cell biology.

Sucrase-isomaltase gene expression in Barrett's esophagus and adenocarcinoma.

D. Beer, M. Orringer, P. Traber, 1993, Gastroenterology.

DNA Methylation Down-regulates CDX1 Gene Expression in Colorectal Cancer Cell Lines*

M. Toyota, E. Rankin, P. Traber, 2002, The Journal of Biological Chemistry.

Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial

S. Neubauer, P. Traber, R. Banerjee, 2018, PloS one.

Sucrase-Isomaltase Gene Expression and Adenocarcinoma

D. Beer, P. Traber, G. Wu, 1993 .

Regression of Fibrosis and Reversal of Cirrhosis in Rats by Galectin Inhibitors in Thioacetamide-Induced Liver Disease

S. Friedman, P. Traber, A. Klyosov, 2013, PloS one.

Therapy of Experimental NASH and Fibrosis with Galectin Inhibitors

P. Traber, E. Zomer, 2013, PloS one.

Phenobarbital induction of cytochrome p‐450 b,e genes is dependent on protein synthesis

P. Traber, J. Gumucio, J. Chianale, 1988, Hepatology.

Physiologic significance and regulation of hepatocellular heterogeneity.

P. Traber, J. Gumucio, J. Chianale, 1988, Gastroenterology.

Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines.

P. Traber, A. Markowitz, L. Chen, 1995, The American journal of physiology.

The human sucrase-isomaltase gene directs complex patterns of gene expression in transgenic mice.

P. Traber, A. Markowitz, E. Birkenmeier, 1993, The American journal of physiology.

Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt-villus axis.

P. Traber, D. Gumucio, Wei Wang, 1991, The American journal of physiology.

cAMP Response Element-binding Protein Interacts with the Homeodomain Protein Cdx2 and Enhances Transcriptional Activity*

P. Traber, Jennifer K Taylor, F. Boudreau, 1999, The Journal of Biological Chemistry.

Expression of cytochrome P450b and P450e genes in small intestinal mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides.

P. Traber, J. Gumucio, E. Wójcik, 1988, The Journal of biological chemistry.

Electron microscopic evaluation of brain edema in rabbits with galactosamine‐induced fulminant hepatic failure: Ultrastructure and integrity of the blood‐brain barrier

D. Ganger, P. Traber, A. Blei, 1987, Hepatology.

Pulmonary hypertension and liver disease.

P. Traber, J. Gumucio, R. Moseley, 1988, Annals of internal medicine.

Regulation of sucrase-isomaltase gene expression along the crypt-villus axis of rat small intestine.

P. Traber, 1990, Biochemical and biophysical research communications.

Long‐term maintenance of the adult pattern of liver‐specific expression for P‐450b, P‐450e, albumin and α‐fetoprotein genes in intrasplenically transplanted hepatocytes

P. Traber, P. Maganto, J. Gumucio, 1990, Hepatology.

Transcriptional Regulation in Intestinal Development

P. Traber, 1999 .

Induction of P-450IIB genes within the rat liver acinus is not dependent on the chemical inducer or on the acinar organization.

P. Traber, P. Maganto, J. Gumucio, 1989, Journal of Biological Chemistry.

Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene

P. Traber, G. Wu, W. Wang, 1992, Molecular and cellular biology.

A multicenter, randomized, double-blind, PLB-controlled trial of Galectin-3 inhibitor (GR-MD-02) in patients with NASH cirrhosis and portal hypertension

N. Chalasani, P. Traber, Z. Goodman, 2018 .

Expression of PRL-1 nuclear PTPase is associated with proliferation in liver but with differentiation in intestine.

P. Traber, D. Silberg, L. Greenbaum, 1996, The American journal of physiology.

P450IIB gene expression in rat small intestine: cloning of intestinal P450IIB1 mRNA using the polymerase chain reaction and transcriptional regulation of induction.

M. McDonnell, P. Traber, J. Gumucio, 1990, Molecular pharmacology.

Vancomycin Ototoxicity in patient with normal renal function.

P. Traber, D. Levine, 1981, Annals of Internal Medicine.

Cancer in inflammatory bowel disease.

P. Traber, G. Lichtenstein, D. Bachwich, 1994, The Medical clinics of North America.

Galectins and disease implications for targeted therapeutics

P. Traber, A. Klyosov, 2012 .

Cdx1 and cdx2 expression during intestinal development.

P. Traber, D. Silberg, E. Suh, 2000, Gastroenterology.

An intestine-specific homeobox gene regulates proliferation and differentiation

P. Traber, E. Suh, P G Traber, 1996, Molecular and cellular biology.

CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium.

E. Furth, P. Traber, D. Silberg, 1997, Gastroenterology.

The Down Regulated in Adenoma (dra) Gene Encodes an Intestine-specific Membrane Sulfate Transport Protein (*)

P. Traber, D. Silberg, R. Moseley, 1995, The Journal of Biological Chemistry.

The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation.

K. Kaestner, P. Traber, D. Silberg, 1997, Genes & development.

Molecular pathogenesis of colorectal cancer.

P. Traber, T. Hoops, Timothy Hoops, 1997, Hematology/oncology clinics of North America.

Expression and regulation of cytochrome P-450I genes (CYP1A1 and CYP1A2) in the rat alimentary tract.

P. Traber, W. Mcdonnell, W. Wang, 1992, Biochimica et biophysica acta.

Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor

Brady Bernard, P. Traber, T. Shimada, 2021, Journal for ImmunoTherapy of Cancer.

Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity

P. Traber, William L. Redmond, Melissa J. Kasiewicz, 2021, Oncoimmunology.

Effects of Belapectin, an Inhibitor of Galectin-3, in Patients with Nonalcoholic Steatohepatitis With Cirrhosis And Portal Hypertension.

H. Conjeevaram, N. Chalasani, D. Rockey, 2019, Gastroenterology.

Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain.

P. Traber, A. Klyosov, K. Mayo, 2016, Glycobiology.

Isolation and characterization of the human sucrase-isomaltase gene and demonstration of intestine-specific transcriptional elements.

P. Traber, G. Wu, W. Wang, 1992, The Journal of biological chemistry.

Sucrase-isomaltase gene expression along crypt-villus axis of human small intestine is regulated at level of mRNA abundance.

P. Traber, T. Judge, G. Wu, 1992, The American journal of physiology.

Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract.

P. Traber, J. Scheiman, W. Mcdonnell, 1992, Gastroenterology.

Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene.

P. Traber, E. Rings, F. Boudreau, 2002, The Journal of biological chemistry.

Randomised clinical study: GR‐MD‐02, a galectin‐3 inhibitor, vs. placebo in patients having non‐alcoholic steatohepatitis with advanced fibrosis

B. Neuschwander‐Tetri, N. Chalasani, P. Traber, 2016, Alimentary pharmacology & therapeutics.

Intestine-specific gene transcription.

P. Traber, D. Silberg, 1996, Annual review of physiology.

Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression

P. Traber, J. Lynch, R. Guo, 2003, Oncogene.

Clusterin gene transcription is activated by caudal-related homeobox genes in intestinal epithelium.

P. Traber, E. Suh, G. Swain, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Sucrase-isomaltase Gene Transcription Requires the Hepatocyte Nuclear Factor-1 (HNF-1) Regulatory Element and Is Regulated by the Ratio of HNF-1α to HNF-1β*

P. Traber, F. Boudreau, Yi Zhu, 2001, The Journal of Biological Chemistry.

Demonstration by in situ hybridization of the zonal modulation of rat liver cytochrome P-450b and P-450e gene expression after phenobarbital.

P. Traber, Eva M. Wojcik, J. Gumucio, 1988, The Journal of clinical investigation.

Hepatocyte nuclear factor-1 alpha (HNF-1 alpha) and HNF-1 beta regulate transcription via two elements in an intestine-specific promoter.

P. Traber, L. Chen, G. Wu, 1994, The Journal of biological chemistry.

Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta.

P. Traber, F. Boudreau, Y. Zhu, 2001, The Journal of biological chemistry.

Transcriptional regulation of intestinal hydrolase biosynthesis during postnatal development in rats.

P. Traber, H. Büller, R. Montgomery, 1994, The American journal of physiology.

Differential regulation of cytochrome P-450 genes along rat intestinal crypt-villus axis.

P. Traber, W. Wang, L. Yu, 1992, American Journal of Physiology.

P. Traber, D. Silberg, E. Suh, 2000, The Journal of Biological Chemistry.

Hepatocyte Nuclear Factor-1α, GATA-4, and Caudal Related Homeodomain Protein Cdx2 Interact Functionally to Modulate Intestinal Gene Transcription

P. Traber, E. Rings, F. Boudreau, 2002, Journal of Biological Chemistry.

Ammonia-induced swelling of rat cerebral cortical slices: Implications for the pathogenesis of brain edema in acute hepatic failure

R. Butterworth, P. Traber, A. Blei, 1989, Metabolic Brain Disease.

Synergistic activity of IL-2 mutein with tolerogenic ImmTOR nanoparticles leads to massive expansion of antigen-specific Tregs and protection against autoimmune disease

Jamie B. Spangler, P. Traber, Ning Li, 2023, bioRxiv.

Detection of hepatitis C viral RNA by the polymerase chain reaction

P. Traber, M. Lucey, P. Traber, 1991, Hepatology.

Epithelial cell growth and differentiation. V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium.

P. Traber, 1997, The American journal of physiology.

V. Transcriptional regulation, development, and neoplasia of the intestinal epithelium.

P. Traber, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Response from GlaxoSmithKline

F. Rockhold, P. Traber, A. Metz, 2002 .

Differentiation of intestinal epithelial cells: lessons from the study of intestine-specific gene expression.

P. Traber, 1994, The Journal of laboratory and clinical medicine.

CREB-binding protein interacts with the homeo- domain protein Cdx2 and enhances transcriptional activity.

P. Traber, F. Boudreau, E. Suh, 1999 .

Phase 2 Dose-Finding Study in Patients with Gout Using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110)

S. Nicolaou, Hyon K. Choi, P. Traber, 2023, Rheumatology and Therapy.

A Novel Colonic Repressor Element Regulates Intestinal Gene Expression by Interacting with Cux/CDP

R. Scheuermann, P. Traber, D. Silberg, 2002, Molecular and Cellular Biology.

Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter.

P. Traber, D. Silberg, A. Markowitz, 1997, The American journal of physiology.

A phase 2a, open‐label pilot study of the galectin‐3 inhibitor GR‐MD‐02 for the treatment of moderate‐to‐severe plaque psoriasis

P. Traber, H. Shlevin, S. Ritchie, 2017, Journal of the American Academy of Dermatology.

The COMPARE head-to-head, randomised-controlled trial of SEL-212 (pegadricase plus rapamycin-containing nanoparticle, ImmTOR™) versus pegloticase for refractory gout.

R. Terkeltaub, Hyon K. Choi, V. Strand, 2023, Rheumatology.

P306 MORF-057, an oral selective α4β7 integrin inhibitor for Inflammatory Bowel Disease, leads to specific target engagement in a single and multiple ascending dose study in healthy subjects

P. Traber, Jennifer Jones, P. Krzeski, 2021 .

Gut patterning: the case of the missing cecum.

P. Traber, 1998, Gastroenterology.

Murine intestinal disaccharidases: identification of structural variants of sucrase-isomaltase complex.

P. Traber, A. Markowitz, B. Underdown, 1993, The American journal of physiology.