P. Berna

发表

Residue accessibility, hydrogen bonding, and molecular recognition: metal-chelate probing of active site histidines in chymotrypsins.

P. Berna, N. Mrabet, J. V. Van Beeumen, 1997, Biochemistry.

Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.

P. Berna, S. Hitier, S. Nénan, 2007, European journal of pharmacology.

How to use immobilized metal ion affinity chromatography

P. Berna, J. Porath, J. Winzerling, 1992 .

Drug discovery and development for spinal muscular atrophy: lessons from screening approaches and future challenges for clinical development.

P. Berna, R. Pruss, T. Bordet, 2010, Future medicinal chemistry.

Cyanocarbons as ligands for electron donor acceptor chromatography of human serum proteins.

P. Berna, J. Porath, 1996, Journal of chromatography. A.

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.

P. Soulard, P. Berna, B. Bertin, 2004, Bioorganic & medicinal chemistry letters.

Translation of TRO40303 from myocardial infarction models to demonstration of safety and tolerance in a randomized Phase I trial

P. Berna, S. Pietri, M. Culcasi, 2014, Journal of Translational Medicine.

Chapter 28. To market, to market — 2000

P. Berna, P. Bernardelli, B. Gaudillière, 2001 .

Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

P. Berna, R. Pruss, T. Bordet, 2010, Pharmaceuticals.

Large-scale production of a therapeutic protein in transgenic tobacco plants: effect of subcellular targeting on quality of a recombinant dog gastric lipase

S. Dufour, A. Doherty, P. Berna, 2001, Molecular Breeding.

Crystal Structure of the Open Form of Dog Gastric Lipase in Complex with a Phosphonate Inhibitor*

P. Berna, R. Verger, C. Cambillau, 2002, The Journal of Biological Chemistry.

Section VII. Trends and perspectives

P. Berna, Bernard Gaudillière, Patrick Berna, 2000 .

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.

P. Soulard, P. Berna, B. Bertin, 2004, Bioorganic & medicinal chemistry letters.

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: metabolism-directed optimization studies towards orally bioavailable derivatives.

P. Berna, R. Wrigglesworth, P. Ducrot, 2004, Bioorganic & medicinal chemistry letters.

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.

P. Berna, B. Bertin, P. Ducrot, 2004, Bioorganic & medicinal chemistry letters.

One-Step Affinity Purification of a Recombinant Cyclodextrin Glycosyl Transferase By (Cu(II), Zn(II) Tandem Column) Immobilized Metal Ion Affinity Chromatography

P. Berna, M. Vijayalakshmi, F. F. Moraes, 1996 .

Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways.

P. Berna, S. Hitier, S. Nénan, 2005, International immunopharmacology.

Effects of depletion of neutrophils or macrophages on the inflammatory response induced by metalloelastase (MMP-12) in mice airways.

P. Berna, S. Hitier, S. Nénan, 2008, European journal of pharmacology.

Comparison of the protein adsorption selectivity of salt-promoted agarose-based adsorbents. Hydrophobic, thiophilic and electron donor-acceptor adsorbents.

P. Berna, J. Porath, S. Oscarsson, 1998, Journal of chromatography. A.

G.O.19 Results of a phase II study to assess safety and efficacy of olesoxime (TRO19622) in 3–25 years old spinal muscular atrophy patients

E. Mercuri, F. Muntoni, F. Rivier, 2014, Neuromuscular Disorders.

Salt-independent adsorption of human serum proteins on cyanocarbon gels.

P. Berna, J. Porath, 1997, Journal of chromatography. B, Biomedical sciences and applications.