C. Lawless

发表

Bayesian Emulation and Calibration of a Stochastic Computer Model of Mitochondrial DNA Deletions in Substantia Nigra Neurons

Darren J. Wilkinson, Richard J. Boys, Daniel A. Henderson, 2009 .

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

C. Lawless, D. Lydall, M. Stark, 2017, G3: Genes, Genomes, Genetics.

Modeling the consequences of heterogeneity in microbial population dynamics

C. Lawless, Helena A. Herrmann, 2017, bioRxiv.

Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites

H. Kimura, C. Lawless, T. Hirota, 2020, Nature Communications.

A senescent cell bystander effect: senescence-induced senescence

C. Lawless, G. Nelson, J. Wordsworth, 2012, Aging cell.

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

Laura C. Greaves, Caroline L. Wilson, C. Lawless, 2014, Nature Communications.

Decoding mitochondrial heterogeneity in single muscle fibres by imaging mass cytometry

Robert W. Taylor, D. Turnbull, C. Lawless, 2020, Scientific Reports.

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

Colin S. Gillespie, Conor Lawless, C. Gillespie, 2012, PloS one.

Quantitative assessment of markers for cell senescence

C. Lawless, T. Zglinicki, D. Jurk, 2010, Experimental Gerontology.

Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast

D. Wilkinson, A. Wipat, C. Lawless, 2011, G3: Genes | Genomes | Genetics.

Quantifying variation in bacterial reproductive fitness with and without antimicrobial resistance: a high-throughput method

C. Lawless, K. P. Lemon, R. Kouyos, 2020, bioRxiv.

Modelling Competition for Nutrients between Microbial Populations Growing on a Solid Agar Surface

C. Lawless, Boocock Daniel, 2017, bioRxiv.

Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network

Robert W. Taylor, D. Turnbull, R. Ogden, 2019, Cell reports.

Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model

C. Lawless, T. von Zglinicki, S. Miwa, 2008, Aging cell.

Pentose Phosphate Pathway Function Affects Tolerance to the G-Quadruplex Binder TMPyP4

D. Wilkinson, C. Lawless, D. Lydall, 2013, PloS one.

Understanding mitochondrial DNA maintenance disorders at the single muscle fibre level

Robert W. Taylor, D. Turnbull, C. Lawless, 2019, Nucleic acids research.

Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network

Robert W. Taylor, D. Turnbull, R. Ogden, 2019, Cell reports.

Sub-cellular Running head: Pathogenesis of mtDNA deletion clonal expansion

D. Turnbull, C. Lawless, M. Picard, 2018 .

Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae

S. Cockell, C. Lawless, D. Lydall, 2015, G3: Genes, Genomes, Genetics.

Bayesian hierarchical modelling for inferring genetic interactions in yeast

Darren J. Wilkinson, David A. Lydall, Conor Lawless, 2014, Journal of the Royal Statistical Society. Series C, Applied statistics.

Subcellular origin of mitochondrial DNA deletions in human skeletal muscle

Robert W. Taylor, C. Cooper, D. Turnbull, 2018, Annals of neurology.

Using mitoribosomal profiling to investigate human mitochondrial translation

R. Agami, C. Lawless, R. Lightowlers, 2017, Wellcome open research.

Fast Bayesian parameter estimation for stochastic logistic growth models

Darren J. Wilkinson, David A. Lydall, Conor Lawless, 2013, Biosyst..

Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast

D. Wilkinson, C. Lawless, D. Lydall, 2017, G3: Genes, Genomes, Genetics.

Systematic analysis of the effects of the DNA damage response network in telomere defective budding yeast

D. Wilkinson, C. Lawless, D. Lydall, 2017, bioRxiv.

Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

Hien-Ping Ngo, David Lydall, Morgan Taschuk, 2011, PLoS genetics.

The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity

C. Lawless, D. Lydall, P. Banks, 2018, Open Biology.

The rise and rise of mitochondrial DNA mutations

Laura C. Greaves, D. Turnbull, C. Lawless, 2020, Open Biology.

Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe

D. Wilkinson, C. Lawless, D. Lydall, 2015, PloS one.

Detecting respiratory chain defects in osteoblasts from osteoarthritic patients using imaging mass cytometry.

D. Turnbull, C. Lawless, David McDonald, 2022, Bone.

Quantifying the effect of uncertainty in soil moisture characteristics on plant growth using a crop simulation model

P. Jamieson, M. Semenov, C. Lawless, 2008 .

Assessing lead-time for predicting wheat growth using a crop simulation model

Mikhail A. Semenov, Conor Lawless, M. Semenov, 2005 .

A Quantitative Fitness Analysis Workflow

C. Lawless, D. Lydall, A.P. Banks, 2012, Journal of visualized experiments : JoVE.

Colonyzer: automated quantification of micro-organism growth characteristics on solid agar

Darren J. Wilkinson, David A. Lydall, Conor Lawless, 2010, BMC Bioinformatics.

Explainable Deep Learning to Profile Mitochondrial Disease Using High Dimensional Protein Expression Data

C. Lawless, A. McGough, A. Vincent, 2022, 2022 IEEE International Conference on Big Data (Big Data).

Quantifying Variation in Bacterial Reproductive Fitness: a High-Throughput Method

C. Lawless, K. P. Lemon, R. Kouyos, 2021, mSystems.

CaliBayes and BASIS: integrated tools for the calibration, simulation and storage of biological simulation models

Darren J. Wilkinson, Colin S. Gillespie, Richard J. Boys, 2010, Briefings Bioinform..

Correction of radiolabel pulse-chase data by a mathematical model: application to mitochondrial turnover studies.

C. Lawless, T. von Zglinicki, S. Miwa, 2010, Biochemical Society transactions.

Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network

Robert W. Taylor, D. Turnbull, R. Ogden, 2019, Cell reports.

T cell differentiation drives the negative selection of pathogenic mitochondrial DNA variants

C. Lawless, G. Gorman, M. Collin, 2023, Life science alliance.

Resistance Exercise Training Rescues Mitochondrial Dysfunction in Skeletal Muscle of Patients with Myotonic Dystrophy Type 1

C. Lawless, G. Gorman, H. Tuppen, 2023, Journal of neuromuscular diseases.

Fast Bayesian parameter estimation for stochastic logistic growth models

D. Wilkinson, C. Lawless, D. Lydall, 2013, Biosyst..

Bayesian hierarchical modelling for inferring genetic interactions in yeast

D. Wilkinson, C. Lawless, D. Lydall, 2015, Journal of the Royal Statistical Society. Series C, Applied statistics.

Mitochondrial morphology and function in mitochondrial disease

C. Lawless, A. Vincent, Ross Laws, 2023, bioRxiv.

Strength training rescues mitochondrial dysfunction in skeletal muscle of patients with myotonic dystrophy type 1

C. Lawless, G. Gorman, H. Tuppen, 2023, medRxiv.