Melvin I. Simon

发表

The Sequence of the Human Genome

Timothy B. Stockwell, William H. Majoros, Helen M. Moore, 2001, Science.

Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα13 Deficiency

Stefan Offermanns, Melvin I. Simon, J. Revel, 1997, Science.

Embryonic cardiomyocyte hypoplasia and craniofacial defects in Gαq. Gα11‐mutant mice

Melvin I. Simon, I. Sarosi, S. Offermanns, 1998 .

An Open Letter to Elias Zerhouni

Jeffrey W. Roberts, N. Cozzarelli, C. Yanofsky, 2005, Science.

LigandsShort-Term Stimulation with 33 Single Expression Changes in Response to Analysis of the Major Patterns of B Cell Gene

R. Scheuermann, Melvin I. Simon, Sangdun Choi, 2004 .

Gq protein α subunits Gαq and Gα11 are localized at postsynaptic extra‐junctional membrane of cerebellar Purkinje cells and hippocampal pyramidal cells

Masahiko Watanabe, T. Iwanaga, M. Kano, 2000, The European journal of neuroscience.

Different α1-Adrenergic Receptor Sequences Required for Activating Different Gα Subunits of Gq Class of G Proteins (*)

Melvin I. Simon, Dianqing Wu, M. Simon, 1995, The Journal of Biological Chemistry.

Muscarinic Inhibition of Calcium Current and M Current in Gαq-Deficient Mice

Melvin I. Simon, J. Haley, S. Offermanns, 2000, The Journal of Neuroscience.

Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cβ in mouse brain

Masahiko Watanabe, M. Kano, Michiko Nakamura, 1998, The European journal of neuroscience.

Gαq signaling is required for Rho‐dependent transcriptional activation of the cyclooxygenase‐2 promoter in fibroblasts

Melvin I. Simon, L. Slice, Sang-kyou Han, 2003, Journal of cellular physiology.

Gα12 and Gα13 Are Phosphorylated during Platelet Activation*

M. Simon, Melvin I. Simon, S. Offermanns, 1996, The Journal of Biological Chemistry.

Tec/Bmx non‐receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Gα12/13

H. Mano, Melvin I. Simon, Dianqing Wu, 1998, The EMBO journal.

Specific Involvement of G Proteins in Regulation of Serum Response Factor-mediated Gene Transcription by Different Receptors*

Melvin I. Simon, Dianqing Wu, J. Mao, 1998, The Journal of Biological Chemistry.

The transforming activity of activated Gα12

M. Simon, Melvin I. Simon, Dianqing Wu, 1993 .

Bacterial Flagella: Polarity of Elongation

M. Simon, S. Emerson, Melvin I. Simon, 1970, Science.

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

M. Simon, Melvin I. Simon, M. Gawaz, 2003, Nature Medicine.

Diversity of G proteins in signal transduction

Melvin I. Simon, N. Gautam, M. Strathmann, 1991, Science.

The DNA sequence of human chromosome 22

Melanie E. Goward, Antony V. Cox, R. Durbin, 1999, Nature.

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

B. Birren, B. Birren, M. Simon, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Homologies between signal transducing G proteins and ras gene products.

J B Hurley, M. Simon, J. Hurley, 1984, Science.

Thrombin Protease-activated Receptor-1 Signals through Gq- and G13-initiated MAPK Cascades Regulating c-Jun Expression to Induce Cell Transformation*

M. Simon, Melvin I. Simon, J. Gutkind, 2003, Journal of Biological Chemistry.

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

M. Simon, Melvin I. Simon, P. Eversole-Cire, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Construction and characterization of a human bacterial artificial chromosome library.

B. Birren, B. Birren, M. Simon, 1996, Genomics.

Transmembrane signal transduction in bacterial chemotaxis involves ligand-dependent activation of phosphate group transfer.

M. Simon, Melvin I. Simon, J. Hess, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Transposon-facilitated DNA sequencing.

M. Palazzolo, Melvin I. Simon, E. Meyerowitz, 1991, Proceedings of the National Academy of Sciences of the United States of America.

G protein-coupled signal transduction pathways for interleukin-8.

Melvin I. Simon, Dianqing Wu, M. Simon, 1993, Science.

Human genome anatomy: BACs integrating the genetic and cytogenetic maps for bridging genome and biomedicine.

B. Birren, L. Hui, X. Wu, 1999, Genome research.

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

M. Simon, P. Casey, A. Gilman, 1990, The Journal of biological chemistry.

Genetic dissection of G protein-coupled signal reduction

P. Sternberg, R. Plasterk, H. Korswagen, 1999 .

Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice.

M. Simon, Melvin I. Simon, J. McCarrey, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits.

M. Simon, A. Gilman, Melvin I. Simon, 1993, The Journal of biological chemistry.

Members of the Gq alpha subunit gene family activate phospholipase C beta isozymes.

Melvin I. Simon, Dianqing Wu, S. Rhee, 1992, Journal of Biological Chemistry.

G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma.

M. Simon, A. Gilman, Melvin I. Simon, 1992, The Journal of biological chemistry.

G protein diversity is increased by associations with a variety of gamma subunits.

M. Simon, Melvin I. Simon, H. Tamir, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells.

M. Simon, Melvin I. Simon, Dianqing Wu, 1992, Journal of Biological Chemistry.

Specific interactions of chemoattractant factor receptors with G-proteins.

M. Simon, Melvin I. Simon, C. Gerard, 1993, The Journal of biological chemistry.

Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.

S. Luoh, M. Simon, Melvin I. Simon, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Fis binding to the recombinational enhancer of the Hin DNA inversion system.

M. Simon, R. C. Johnson, Reid C. Johnson, 1987, Genes & development.

Diphtheria toxin forms transmembrane channels in planar lipid bilayers.

M. Simon, Melvin I. Simon, R. Draper, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Recoverin Regulates Light-dependent Phosphodiesterase Activity in Retinal Rods

D. Baylor, M. Simon, C. Makino, 2004, The Journal of general physiology.

Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines.

M. Simon, Melvin I. Simon, M. Strathmann, 1991, Proceedings of the National Academy of Sciences of the United States of America.

G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells.

M. Simon, Melvin I. Simon, V. Slepak, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Activation of phospholipase C by alpha 1-adrenergic receptors is mediated by the alpha subunits of Gq family.

M. Simon, Melvin I. Simon, Dianqing Wu, 1992, The Journal of biological chemistry.

Sequence of the alpha subunit of photoreceptor G protein: homologies between transducin, ras, and elongation factors.

J. Hurley, Melvin I. Simon, M. Simon, 1985, Science.

Hyphal development in Neurospora crassa: involvement of a two-component histidine kinase.

M. Simon, Melvin I. Simon, L. Alex, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The response regulators CheB and CheY exhibit competitive binding to the kinase CheA.

M. Simon, Melvin I. Simon, R. Weis, 1995, Biochemistry.

Complete nucleotide sequence of two generations of a bacterial artificial chromosome cloning vector.

K. Wang, M. Simon, C. Boysen, 1997, BioTechniques.

The carboxy-terminal portion of the CheA kinase mediates regulation of autophosphorylation by transducer and CheW

M. Simon, Melvin I. Simon, R. Bourret, 1993, Journal of bacteriology.

Phase variation in Salmonella: analysis of Hin recombinase and hix recombination site interaction in vivo.

M. Simon, P. Youderian, Melvin I. Simon, 1988, Genes & development.

Diphtheria toxin has the properties of a lectin.

M. Simon, Melvin I. Simon, R. Draper, 1978, Proceedings of the National Academy of Sciences of the United States of America.