I. Sargent

发表

Relationships between the developmental potential of human in-vitro fertilization embryos and features describing the embryo, oocyte and follicle.

R. Saith, A. Srinivasan, D. Michie, 1998, Human reproduction update.

The Immunomodulatory Role of Syncytiotrophoblast Microvesicles

I. Sargent, C. Redman, J. Southcombe, 2011, PloS one.

Isolation of syncytiotrophoblast microvesicles and exosomes and their characterisation by multicolour flow cytometry and fluorescence Nanoparticle Tracking Analysis

D. Ferguson, I. Sargent, C. Redman, 2015, Methods.

Placental Disease and the Maternal Syndrome of Preeclampsia: Missing Links?

I. Sargent, D. Tannetta, 2013, Current Hypertension Reports.

Syncytiotrophoblast extracellular vesicles – Circulating biopsies reflecting placental health

I. Sargent, C. Redman, M. Vatish, 2017, Placenta.

Update of syncytiotrophoblast derived extracellular vesicles in normal pregnancy and preeclampsia.

I. Sargent, C. Redman, M. Vatish, 2017, Journal of reproductive immunology.

Multicolor Flow Cytometry and Nanoparticle Tracking Analysis of Extracellular Vesicles in the Plasma of Normal Pregnant and Pre-eclamptic Women1

I. Sargent, C. Redman, J. Southcombe, 2013, Biology of reproduction.

Changes in Microparticle Numbers and Cellular Origin During Pregnancy and Preeclampsia

I. Sargent, R. Nieuwland, J. V. D. van der Post, 2008, Hypertension in pregnancy.

Trophoblast deportation in human pregnancy--its relevance for pre-eclampsia.

I. Sargent, C. Redman, M. Johansen, 1999, Placenta.

HLA-G suppresses proliferation of CD4(+) T-lymphocytes.

I. Sargent, S. Ellis, D. Bainbridge, 2000, Journal of reproductive immunology.

Microparticle association and heterogeneity of tumor‐derived tissue factor in plasma: is it important for coagulation activation?

I. Sargent, V. Bogdanov, L. Robles-Carrillo, 2014, Journal of thrombosis and haemostasis : JTH.

Syncytiotrophoblast Microvesicles Released from Pre-Eclampsia Placentae Exhibit Increased Tissue Factor Activity

I. Sargent, C. Redman, D. Tannetta, 2011, PloS one.

The secretion and effect of inhibin A, activin A and follistatin on first-trimester trophoblasts in vitro.

E. Jauniaux, I. Sargent, S. Muttukrishna, 2005, European journal of endocrinology.

NK cells and human pregnancy--an inflammatory view.

I. Sargent, C. Redman, A. Borzychowski, 2006, Trends in immunology.

Heparin-binding epidermal growth factor significantly improves human blastocyst development and hatching in serum-free medium.

D H Barlow, I. Sargent, D. Barlow, 1998, Human reproduction.

Masses Preimplantation Embryos and Inner Cell Spliced Transcripts of HLA-G in Human Differential Expression of Alternatively

I. Sargent, D. Barlow, Yuan-Qing Yao, 2005 .

Differential Expression of Alternatively Spliced Transcripts of HLA-G in Human Preimplantation Embryos and Inner Cell Masses

I. Sargent, D. Barlow, Yuan-Qing Yao, 2005, The Journal of Immunology.

Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta.

I. Sargent, C. Redman, C. Boyd, 2004, Journal of reproductive immunology.

An in-vitro model for stromal invasion during implantation of the human blastocyst.

I. Sargent, D. Barlow, H. Mardon, 2003, Human reproduction.

Heparin-binding epidermal growth factor and its receptor ErbB4 mediate implantation of the human blastocyst

J. Heath, I. Sargent, D. Barlow, 2002, Mechanisms of Development.

The use of recombinant growth factors to promote human embryo development in serum-free medium.

I. Sargent, D. Barlow, K. Martin, 1998, Human Reproduction.

Caveolin-1 and lipid rafts in confluent BeWo trophoblasts: evidence for Rock-1 association with caveolin-1.

I. Sargent, C. Redman, C. Boyd, 2007, Placenta.

Pre-eclampsia: Immunological factors and placentation: implications for pre-eclampsia

I. Sargent, C. Redman, 2007 .

Immunological factors and placentation: Implications for pre-eclampsia

I. Sargent, Redman Cwg., 2007 .

Monocytes are primed to produce the Th1 type cytokine IL‐12 in normal human pregnancy: an intracellular flow cytometric analysis of peripheral blood mononuclear cells

I. Sargent, C. Redman, G. Sacks, 2003, Clinical and experimental immunology.

In vitro placenta barrier model using primary human trophoblasts, underlying connective tissue and vascular endothelium.

M. Matsusaki, M. Akashi, I. Sargent, 2019, Biomaterials.

IFPA Senior Award Lecture: making sense of pre-eclampsia - two placental causes of preeclampsia?

I. Sargent, A. Staff, C. Redman, 2014, Placenta.

Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation

A. Buchan, I. Sargent, D. Anthony, 2017, Scientific Reports.

Hypoxia alters expression and function of syncytin and its receptor during trophoblast cell fusion of human placental BeWo cells: implications for impaired trophoblast syncytialisation in pre-eclampsia.

I. Sargent, C. Boyd, C. Redman, 2003, Biochimica et biophysica acta.

Cardiovascular Risk Factors in Children and Young Adults Born to Preeclamptic Pregnancies: A Systematic Review

Y. Kenworthy, A. Wilkinson, I. Sargent, 2012, Pediatrics.

Cardiovascular Risk Factors in Children and Young Adults Born to Preeclamptic Pregnancies: A Systematic Review

Y. Kenworthy, A. Wilkinson, I. Sargent, 2012, Pediatrics.

Maternal and fetal immune responses during pregnancy.

I. Sargent, 1993, Experimental and clinical immunogenetics.

Detection of human white cell proliferative responses by immunoenzymatic measurement of bromodeoxyuridine uptake.

I. Sargent, D. Mason, J. Magaud, 1988, Journal of immunological methods.

Placental stress and pre-eclampsia: a revised view.

I. Sargent, C. Redman, 2009, Placenta.

reeclampsia and the ystemic Inflammatory Response hristopher

I. Sargent, W. Redman, 2004 .

Measurement of circulating cell-derived microparticles by flow cytometry: sources of variability within the assay.

B. Ferry, I. Sargent, R. Nieuwland, 2011, Thrombosis research.

Localization of tumour necrosis factor production in cells at the materno/fetal interface in human pregnancy

I. Sargent, C. Redman, L. Clover, 1992, Clinical and experimental immunology.

Double immunocytochemical labeling of cell and tissue samples with monoclonal anti-bromodeoxyuridine.

P. J. Clarke, I. Sargent, D. Mason, 1989, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia.

I. Sargent, C. Redman, Y. Lo, 1999, Clinical chemistry.

Evidence for a novel HLA antigen found on human extravillous trophoblast and a choriocarcinoma cell line.

A. McMichael, I. Sargent, C. Redman, 1986, Immunology.

Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticles

I. Sargent, C. Redman, G. Sacks, 2007, The Journal of Immunology.

Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells − implication for placental cell fusion

I. Sargent, H. Christian, C. Redman, 2007, The FEBS journal.

Differential effect of cross-linking the CD98 heavy chain on fusion and amino acid transport in the human placental trophoblast (BeWo) cell line.

I. Sargent, H. Christian, C. Redman, 2007, Biochimica et biophysica acta.

The short forms of HLA-G are unlikely to play a role in pregnancy because they are not expressed at the cell surface.

I. Sargent, S. Ellis, D. Bainbridge, 2000, Journal of reproductive immunology.

HLA-DR is aberrantly expressed at feto-maternal interface in pre-eclampsia.

I. Sargent, C. Redman, G. Scambia, 2018, Journal of reproductive immunology.

HLA class I molecules in the placenta: which ones, where and what for? A workshop report.

I. Sargent, P. Le Bouteiller, 2000, Placenta.

Cell populations in the human early pregnancy decidua: natural killer activity and response to interleukin-2 of CD56-positive large granular lymphocytes.

B. Ferry, I. Sargent, C. Redman, 1990, Immunology.

Syncytiotrophoblast extracellular vesicles impair rat uterine vascular function via the lectin-like oxidized LDL receptor-1

I. Sargent, T. Sawamura, S. Davidge, 2017, PloS one.

Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre‐eclamptic pregnancies

I. Sargent, M. Knight, C. Redman, 1998, British journal of obstetrics and gynaecology.

Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

I. Sargent, N. Martin, D. Anthony, 2014, Journal of Neuroinflammation.

Micromanipulation of human embryos to assist hatching.

I. Sargent, B. Gosden, D. Barlow, 1994, Fertility and sterility.

An analysis using DNA microarray of the time course of gene expression during syncytialization of a human placental cell line (BeWo).

T. Freeman, I. Sargent, C. Boyd, 2004, Placenta.

The origins and end-organ consequence of pre-eclampsia.

I. Sargent, M. Brown, G. Eastabrook, 2011, Best practice & research. Clinical obstetrics & gynaecology.

Conditioned medium from human decidual stromal cells has a concentration-dependent effect on trophoblast cell invasion.

T. Han, I. Sargent, Y. Yao, 2009, Placenta.

Placental Vesicles Carry Active Endothelial Nitric Oxide Synthase and Their Activity is Reduced in Preeclampsia

I. Sargent, C. Redman, U. Kishore, 2017, Hypertension.

An Overview of Novel and Conventional Methods to Detect Extracellular Vesicles

I. Sargent, P. Harrison, C. Gardiner, 2014 .

The functions of microparticles in pre-eclampsia.

I. Sargent, R. Nieuwland, J. V. D. van der Post, 2011, Seminars in thrombosis and hemostasis.

Localisation of proteins of iron metabolism in the human placenta and liver

I. Sargent, A. Townsend, M. Rees, 2006, British journal of haematology.

Investigation of the actin scavenging system in pre-eclampsia

I. Sargent, C. Redman, D. Tannetta, 2014, European journal of obstetrics, gynecology, and reproductive biology.

Immunoregulation in normal pregnancy and pre-eclampsia: an overview.

I. Sargent, C. Redman, A. Borzychowski, 2006, Reproductive biomedicine online.

Complement component C1q as potential diagnostic but not predictive marker of preeclampsia

I. Sargent, T. Stampalija, F. Tedesco, 2016, American journal of reproductive immunology.

Excess syncytiotrophoblast microparticle shedding is a feature of early-onset pre-eclampsia, but not normotensive intrauterine growth restriction.

L. Magee, I. Sargent, C. Redman, 2006, Placenta.

ST2 and IL-33 in Pregnancy and Pre-Eclampsia

I. Sargent, C. Redman, J. Southcombe, 2011, PloS one.

Purification and characterization of a complex from placental syncytiotrophoblast microvillous membranes which inhibits the proliferation of human umbilical vein endothelial cells.

I. Sargent, A. Willis, C. Redman, 1999, Placenta.

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions

M. Matsusaki, M. Akashi, M. Giugliano, 2014, Experimental Neurology.

Maternal Circulating Levels of Activin A, Inhibin A, sFlt-1 and Endoglin at Parturition in Normal Pregnancy and Pre-Eclampsia

I. Sargent, C. Redman, S. Muttukrishna, 2009, PloS one.

Extracellular Vesicles in Health and Disease

I. Sargent, P. Harrison, C. Gardiner, 2014 .

IMMUNOLOGICAL ASPECTS OF HUMAN PREGNANCY AND ITS DISORDERS

I. Sargent, C. Redman, L. Sutton, 1984 .

Cell populations in human early pregnancy decidua: characterization and isolation of large granular lymphocytes by flow cytometry.

I. Sargent, C. Redman, P. Starkey, 1988, Immunology.

Textbook of Clinical Embryology: Reproductive immunology

I. Sargent, 2013 .

Characterisation of Syncytiotrophoblast Vesicles in Normal Pregnancy and Pre-Eclampsia: Expression of Flt-1 and Endoglin

I. Sargent, C. Redman, D. Tannetta, 2013, PloS one.

Flow cytometric characterisation of cell populations in human pregnancy decidua and isolation of decidual macrophages.

I. Sargent, C. Redman, G. Vince, 1990, Journal of immunological methods.

NK cells and pre-eclampsia.

I. Sargent, C. Redman, A. Borzychowski, 2007, Journal of reproductive immunology.

Changes in systemic type 1 and type 2 immunity in normal pregnancy and pre‐eclampsia may be mediated by natural killer cells

I. Sargent, C. Redman, B. Croy, 2005, European journal of immunology.

Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules

I. Sargent, C. Redman, M. Vatish, 2015, Oncotarget.

Flow cytometric measurement of intracellular Th1 and Th2 cytokine production by human villous and extravillous cytotrophoblast.

I. Sargent, C. Redman, L. Clover, 2001, Placenta.

The effect of placental syncytiotrophoblast microvillous membranes from normal and pre‐eclamptic women on the growth of endothelial cells in vitro

I. Sargent, C. Redman, A. Smarason, 1993, British journal of obstetrics and gynaecology.

Trophoblast Glycoprotein (TPGB/5T4) in Human Placenta: Expression, Regulation, and Presence in Extracellular Microvesicles and Exosomes

S. K. Kshirsagar, I. Sargent, T. Fields, 2018, Reproductive Sciences.

Reduced placental protein 13 (PP13) in placental derived syncytiotrophoblast extracellular vesicles in preeclampsia - A novel tool to study the impaired cargo transmission of the placenta to the maternal organs.

I. Sargent, C. Redman, H. Meiri, 2018, Placenta.

Detection of Soluble ST2 in Human Follicular Fluid and Luteinized Granulosa Cells

I. Sargent, C. Redman, J. Southcombe, 2013, PloS one.

Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial function

L. Poston, I. Sargent, C. Redman, 1997, British journal of obstetrics and gynaecology.

Trophoblast deportation in pre‐eclamptic pregnancy

I. Sargent, T. Wilkins, S. Chua, 1991, British journal of obstetrics and gynaecology.

Effect of cytokines and growth factors on the secretion of inhibin A, activin A and follistatin by term placental villous trophoblasts in culture.

I. Sargent, S. Muttukrishna, N. Groome, 2001, European journal of endocrinology.

HLA-G remains a mystery.

D. Bainbridge, I. Sargent, P. Le Bouteiller, 2001, Trends in immunology.

Little evidence of HLA-G mRNA polymorphism in Caucasian or Afro-Caribbean populations.

I. Sargent, S. Ellis, D. Bainbridge, 1999, Journal of immunology.

Afro-Caribbean Populations Polymorphism in Caucasian or Little Evidence of HLA-G mRNA

I. Sargent, S. Ellis, D. Bainbridge, 1999 .

Matrix metalloprotease-9, placental syncytiotrophoblast and the endothelial dysfunction of pre-eclampsia.

I. Sargent, C. Redman, I. Spyropoulou, 2003, Placenta.

Circulating Platelet-derived and Placenta-derived Microparticles Expose Flt-1 in Preeclampsia

I. Sargent, R. Nieuwland, J. V. D. van der Post, 2008, Reproductive Sciences.

Excess syncytiotrophoblast microparticle shedding is a feature of pre-eclampsia, but not normotensive intrauterine growth restriction.

L. Magee, I. Sargent, P. Dadelszen, 2004 .

Cellpopulations inhumanearly pregnancy decidua: characterization andisolation oflarge granular lymphocytes byflowcytometry

I. Sargent, C. Redman, P. Starkey, 1988 .

Measurement of sST2 is comparable to PlGF in the diagnosis of early-onset pre-eclampsia.

I. Sargent, C. Redman, P. von Dadelszen, 2013, Pregnancy hypertension.

Vitamins C and E inhibit apoptosis of cultured human term placenta trophoblast.

I. Sargent, C. Redman, D. Tannetta, 2008, Placenta.

Preeclampsia and the systemic inflammatory response.

I. Sargent, C. Redman, 2004, Seminars in nephrology.

Interleukin-12 and pre-eclampsia.

I. Sargent, C. Redman, G. Sacks, 1997, Journal of reproductive immunology.

Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function

Chris I. Jones, D. Ferguson, I. Sargent, 2015, PLoS ONE.

Alterations in vascular function by syncytiotrophoblast extracellular vesicles via lectin-like oxidized low-density lipoprotein receptor-1 in mouse uterine arteries.

I. Sargent, T. Sawamura, S. Davidge, 2018, Clinical science.

MATERNAL IMMUNE RESPONSES TO THE FETUS IN EARLY PREGNANCY AND RECURRENT MISCARRIAGE

I. Sargent, C. Redman, C. Redman, 1988, The Lancet.

Pre-eclampsia and the systemic inflammatory response

I. Sargent, C. Redman, 2006 .

Activation of peripheral leukocytes in rat pregnancy and experimental preeclampsia.

I. Sargent, C. Redman, M. Faas, 2000, American journal of obstetrics and gynecology.

Activin and follistatin in female reproduction

I. Sargent, N. Groome, D. Tannetta, 2004, Molecular and Cellular Endocrinology.

Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta.

R. Fauchet, I. Sargent, P. Le Bouteiller, 1995, Journal of immunology.

Pre-eclampsia, the placenta and the maternal systemic inflammatory response--a review.

I. Sargent, C. Redman, I L Sargent, 2003, Placenta.

The Human Placenta

I. Sargent, C. Redman, P. Starkey, 1993 .

An innate view of human pregnancy.

I. Sargent, C. Redman, G. Sacks, 1999, Immunology today.

Trophoblast deportation and the maternal inflammatory response in pre-eclampsia.

I. Sargent, C. Redman, G. Sacks, 2003, Journal of reproductive immunology.

Immunomodulation in Normal Pregnancy and Pre-Eclampsia

I. Sargent, C. Redman, M. Knight, 1999 .

Modulation of indoleamine 2,3-dioxygenase by interferon-gamma in human placental chorionic villi.

I. Sargent, C. Boyd, C. Redman, 2000, Molecular human reproduction.

Endothelial cell proliferation is suppressed by plasma but not serum from women with preeclampsia.

I. Sargent, C. Redman, A. Smarason, 1996, American journal of obstetrics and gynecology.

Preeclampsia: An Excessive Maternal Inflammatory Response to Pregnancy

I. Sargent, C. Redman, Christopher W.G. Redman, 1999 .

Extracellular Vesicles in Cardiovascular Disease

I. Sargent, P. Harrison, C. Gardiner, 2014 .

Isolating and Analyzing Fetal Leukocytes in Maternal Blood a

I. Sargent, C. Redman, C. Redman, 1994, Annals of the New York Academy of Sciences.

Clinical Experience: Isolating Trophoblasts from Maternal Blood a

I. Sargent, S. Chua, C. Redman, 1994, Annals of the New York Academy of Sciences.

Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy decidua.

B. Ferry, I. Sargent, C. Redman, 1991, Cellular immunology.

System y+ Arginine Transport and NO Production in Peripheral Blood Mononuclear Cells in Pregnancy and Preeclampsia

I. Sargent, C. Redman, P. Ayuk, 2006, Hypertension.

Preeclampsia and the systemic inflammatory response.

I. Sargent, C. Redman, 2004, Seminars in nephrology.

Decreased tryptophan catabolism by placental indoleamine 2,3-dioxygenase in preeclampsia.

I. Sargent, C. Redman, C. Boyd, 2003, American journal of obstetrics and gynecology.

Tryptophan degradation by human placental indoleamine 2,3‐dioxygenase regulates lymphocyte proliferation

I. Sargent, C. Boyd, Y. Kudo, 2001, The Journal of physiology.

A controlled assessment of direct intraperitoneal insemination.

I. Sargent, D. Barlow, J. Ellis, 1992 .

Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing

I. Sargent, R. Nieuwland, A. Sturk, 2014, Journal of thrombosis and haemostasis : JTH.

Latest Advances in Understanding Preeclampsia

I. Sargent, C. Redman, 2005, Science.

Leukaemia inhibitory factor significantly enhances the blastocyst formation rates of human embryos cultured in serum-free medium.

I. Sargent, D. Barlow, G. F. Dunglison, 1996, Human reproduction.

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

Paul J. Harrison, Peter J. Dobson, Bob Carr, 2011, Nanomedicine : nanotechnology, biology, and medicine.

Preeclampsia: an excessive maternal inflammatory response to pregnancy.

I. Sargent, C. Redman, G. Sacks, 1999, American journal of obstetrics and gynecology.

ED(27) trophoblast-like cells isolated from first-trimester chorionic villi are genetically identical to HeLa cells yet exhibit a distinct phenotype.

Y. Li, I. Sargent, D. Kniss, 2002, Placenta.

Two-way cell traffic between mother and fetus: biologic and clinical implications.

I. Sargent, B. Thilaganathan, Y. Lo, 1996, Blood.

Increased expression of major histocompatibility complex (MHC) class I transplantation antigens in bovine trophoblast cells before fusion with maternal cells.

I. Sargent, S. Ellis, D. Bainbridge, 2001, Reproduction.

Modulation of indoleamine 2,3-dioxygenase by interferon-gamma in human placental chorionic villi.

I. Sargent, C. Redman, C. Boyd, 2000, Molecular human reproduction.

Maternal Immune Responses to the Fetus in Human Pregnancy

I. Sargent, C. Redman, 1989 .

A three-colour flow cytometry technique for measuring trophoblast intracellular antigens: the relative expression of TAP1 in human cytotrophoblast and decidual cells.

I. Sargent, C. Redman, L. Clover, 2000, Placenta.

Isolation of cell island cytotrophoblast from first trimester human placenta, and comparison of antigen expression on villus and extravillus cytotrophoblast

I. Sargent, C. Redman, L. Clover, 1994 .

Isolation and characterisation of a subpopulation of human chorionic cytotrophoblast using a monoclonal anti-trophoblast antibody (NDOG2) in flow cytometry.

I. Sargent, C. Redman, J. Caulfield, 1992, Journal of reproductive immunology.

Maternal cell-mediated immunity to the fetus in human pregnancy.

I. Sargent, C. Redman, 1985, Journal of reproductive immunology.

Purification of human cytotrophoblast from term amniochorion by flow cytometry.

I. Sargent, C. Redman, P. Starkey, 1990, Placenta.

Maternal cell-mediated immunity in normal and pre-eclamptic pregnancy.

I. Sargent, C. Redman, G. Stirrat, 1982, Clinical and experimental immunology.

Expression of TAP1 by human trophoblast

R. Tampé, I. Sargent, L. Clover, 1995, European journal of immunology.

Antigenic heterogeneity of human cytotrophoblast and evidence for the transient expression of MHC class I antigens distinct from HLA-G.

I. Sargent, C. Redman, L. Clover, 1993, Placenta.

Maternal cell-mediated sensitisation to paternal HLA may occur, but is not a regular event in normal human pregnancy.

I. Sargent, C. Redman, J. Arenas, 1987, Journal of reproductive immunology.

Downregulation of Caveolin-1 Enhances Fusion of Human BeWo Choriocarcinoma Cells

I. Sargent, C. Redman, G. Collett, 2010, PloS one.

MHC class II-positive antigen-presenting cells in the decidua.

I. Sargent, R. Searle, P. Starkey, 1988, Immunology today.

Presence of fetal DNA in maternal plasma and serum

I. Sargent, C. Redman, Y. Lo, 1997, The Lancet.

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

Chris Gardiner, A. Schapira, J. Cooper, 2011, Neurobiology of Disease.

Human trophectoderm biopsy and secretion of chorionic gonadotrophin.

I. Sargent, D. Barlow, R. Gardner, 1991, Human reproduction.

RhoE Is Regulated by Cyclic AMP and Promotes Fusion of Human BeWo Choriocarcinoma Cells

I. Sargent, C. Redman, G. Collett, 2012, PloS one.

Maternal cell-mediated immunity in pregnancy--lymphocyte responses of mothers and their non-pregnant HLA identical sisters to paternal HLA.

I. Sargent, C. Redman, A. Ting, 1983, Clinical and experimental immunology.

Detection of antisperm antibodies in seminal plasma by flow cytometry: comparison with the indirect immunobead binding test.

I. Sargent, D. Barlow, S. C. Nicholson, 1997, Fertility and sterility.

Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma.

N M Hjelm, C Fidler, I. Sargent, 1998, The New England journal of medicine.

Human blastocyst grading: an indicator of developmental potential?

D H Barlow, I. Sargent, D. Barlow, 1993, Human reproduction.

The human placenta : a guide for clinicians and scientists

I. Sargent, C. Redman, P. Starkey, 1993 .

Embryotoxicity as a Marker for Recurrent Pregnancy Loss

I. Sargent, A. Dokras, Anuja Dokras, 1996, American journal of reproductive immunology.

An investigation of methods for enriching trophoblast from maternal blood

I. Sargent, Kim Smith, M. Knight, 1995, Prenatal diagnosis.

Quantifying the syncytialisation of human placental trophoblast BeWo cells grown in vitro.

I. Sargent, P. Cook, C. Boyd, 2003, Biochimica et biophysica acta.

REVIEW ARTICLE: Immunology of Pre‐Eclampsia

I. Sargent, C. Redman, 2010, American journal of reproductive immunology.

Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cells

I. Sargent, S. Hansson, M. Belting, 2017, Scientific Reports.

Placental debris, oxidative stress and pre-eclampsia.

I. Sargent, C. Redman, C. Redman, 2000, Placenta.

Differential expression profile of microRNAs in human placentas from preeclamptic pregnancies vs normal pregnancies.

T. Han, I. Sargent, Yuan-Qing Yao, 2009, American journal of obstetrics and gynecology.

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes.

A. Harris, I. Sargent, H. Turley, 2010, Blood.

An approach to preimplantation diagnosis of β‐thalassaemia

I. Sargent, J. Old, N. Varawalla, 1991 .

Detection of fetal cells in maternal blood

I. Sargent, S. Thein, S. Thein, 1991, Prenatal diagnosis.

Role of Lectin-like Oxidized LDL Receptor-1 and Syncytiotrophoblast Extracellular Vesicles in the Vascular Reactivity of Mouse Uterine Arteries During Pregnancy

I. Sargent, T. Sawamura, S. Davidge, 2020, Scientific Reports.

Placental extracellular vesicles express active dipeptidyl peptidase IV; levels are increased in gestational diabetes mellitus

I. Sargent, C. Redman, M. Vatish, 2019, Journal of extracellular vesicles.

Extracellular vesicle sizing and enumeration by nanoparticle tracking analysis

Chris Gardiner, I. Sargent, C. Redman, 2013, Journal of extracellular vesicles.

Trophectoderm biopsy in human blastocysts.

I. Sargent, D. Barlow, R. Gardner, 1990, Human reproduction.

Innate immunity in pregnancy.

I. Sargent, C. Redman, G. Sacks, 2000, Immunology today.

Adrenomedullin: Multiple functions in human pregnancy

I. Sargent, M. Rees, Caroline R Wilson, 2004, Angiogenesis.

Pregnancy hypertension: An international journal of women's cardiovascular health.

I. Sargent, F. Lyall, M. Rezk, 2021, Pregnancy hypertension.

The effect of labour and placental separation on the shedding of syncytiotrophoblast microparticles, cell-free DNA and mRNA in normal pregnancy and pre-eclampsia.

W. Holzgreve, I. Sargent, C. Redman, 2008, Placenta.

The pathogenesis of pre-eclampsia.

I. Sargent, C. Redman, 2001, Gynecologie, obstetrique & fertilite.

Systemic Inflammatory Priming in Normal Pregnancy and Preeclampsia: The Role of Circulating Syncytiotrophoblast Microparticles1

I. Sargent, C. Redman, G. Sacks, 2007, The Journal of Immunology.

Inflammation and pre-eclampsia.

I. Sargent, C. Redman, A. Borzychowski, 2006, Seminars in fetal & neonatal medicine.

Dual action of leucocyte dialysates and of thymosin on the recovery of sheep-cell-rosetting capacity in trypsinized human lymphocytes.

I. Sargent, H. Valdimarsson, M. R. Salaman, 1982, Clinical and experimental immunology.

EFFECTS OF TRANSFER FACTOR (TF) AND THYMOSIN ON THE RECOVERY OF E-ROSETTING CAPACITY IN TRYPSINISED LYMPHOCYTES

I. Sargent, H. Valdimarsson, M. R. Salaman, 1979 .

Chapter 8 – Immunology of Normal Pregnancy and Preeclampsia

Robert N. Taylor, I. Sargent, C. Redman, 2015 .

Immunology of Normal Pregnancy and Preeclampsia

I. Sargent, J. Roberts, Redman Cwg., 2009 .

Soluble HLA-G in IVF/ICSI embryo culture supernatants does not always predict implantation success: a multicentre study.

J. Foidart, C. Munaut, I. Sargent, 2009, Reproductive biomedicine online.

sHLA-G production by human IVF embryos: can it be measured reliably?

I. Sargent, P. Le Bouteiller, J. Tabiasco, 2007, Journal of reproductive immunology.

Does 'soluble' HLA-G really exist? Another twist to the tale.

I. Sargent, 2005, Molecular human reproduction.

Effects of human transfer factor on the migration of guinea-pig macrophages: is there an antigen-specific activity?

I. Sargent, M. R. Salaman, 1980, Immunology.

Exosome-mediated delivery of siRNA in vitro and in vivo

I. Sargent, M. Wood, S. El-Andaloussi, 2012, Nature Protocols.

Immunoregulation in normal pregnancy and pre-eclampsia: an overview.

I. Sargent, C. Redman, A. Borzychowski, 2007, Reproductive biomedicine online.

Effect of syncytiotrophoblast microvillous membrane treatment on gene expression in human umbilical vein endothelial cells

I. Sargent, C. Redman, R. Borup, 2006, BJOG : an international journal of obstetrics and gynaecology.

Endothelial cells and peripheral blood mononuclear cells are a potential source of extraplacental activin a in preeclampsia.

I. Sargent, C. Redman, D. Tannetta, 2003, The Journal of clinical endocrinology and metabolism.

Interleukin‐1 family cytokines and their regulatory proteins in normal pregnancy and pre‐eclampsia

I. Sargent, C. Redman, J. Southcombe, 2015, Clinical and experimental immunology.

CD11b expression on circulating neutrophils in pre-eclampsia.

I. Sargent, C. Redman, K. Studená, 1997, Clinical science.

Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover

I. Sargent, M. Wood, Y. Aoki, 2013, Nucleic acids research.

Pre‐eclampsia affects procalcitonin production in placental tissue

G. Ricci, I. Sargent, P. Zacchi, 2018, American journal of reproductive immunology.

Sera from women with unexplained infertility inhibit both mouse and human embryo growth in vitro.

I. Sargent, D. Barlow, C. Redman, 1993, Fertility and sterility.

The human blastocyst: morphology and human chorionic gonadotrophin secretion in vitro.

I. Sargent, D. Barlow, R. Gardner, 1991, Human reproduction.

Circulating microparticles in normal pregnancy and pre-eclampsia.

I. Sargent, C. Redman, 2008, Placenta.

Giovanni Camussi, Federica Collino, and Maria C. Deregibus 3.1 Introduction

I. Sargent, P. Harrison, C. Gardiner, 2014 .

Immunological properties of human decidual macrophages--a possible role in intrauterine immunity.

I. Sargent, U. Kishore, U. Singh, 2005, Reproduction.

Measurement of refractive index by nanoparticle tracking analysis reveals heterogeneity in extracellular vesicles

Chris Gardiner, I. Sargent, C. Redman, 2014, Journal of extracellular vesicles.

Prophylaxis of recurrent preeclampsia: low-molecular-weight heparin plus low-dose aspirin versus low-dose aspirin alone

I. Sargent, S. Muttukrishna, Redman Cwg., 2006 .

In vitro fertilisation in a small unit in the NHS

I. Sargent, H. O’Reilly, D. Little, 1988, British medical journal.

Antiendometrial Antibodies in Endometriosis Measured by an Enzyme-Linked Immunosorbent Assay Before and After Treatment With Danazol and Nafarelin

I. Sargent, D. Barlow, S. Kennedy, 1990, Obstetrics and gynecology.

Localization of anti‐endometrial antibody binding in women with endometriosis using a double‐labelling immunohistochemical method

I. Sargent, P. Starkey, S. Kennedy, 1990, British journal of obstetrics and gynaecology.

Capture-Based Assays for Extracellular Vesicles within the Blood

I. Sargent, P. Harrison, C. Gardiner, 2014 .

Syncytiotrophoblast Vesicles Show Altered micro-RNA and Haemoglobin Content after Ex-vivo Perfusion of Placentas with Haemoglobin to Mimic Preeclampsia

I. Sargent, C. Redman, S. Hansson, 2014, PloS one.

The functions of microparticles in preeclampsia.

I. Sargent, R. Nieuwland, J. V. D. van der Post, 2011, Pregnancy hypertension.

Extracellular vesicles in normal pregnancy and pre-eclampsia

I. Sargent, C. Redman, D. Tannetta, 2014 .

Review: Does size matter? Placental debris and the pathophysiology of pre-eclampsia.

I. Sargent, C. Redman, J. Southcombe, 2012, Placenta.

Peripheral blood invariant natural killer T cells throughout pregnancy and in preeclamptic women

I. Sargent, C. Redman, J. Southcombe, 2010, Journal of reproductive immunology.

A controlled assessment of direct intraperitoneal insemination

I. Sargent, S. Kennedy, J. D. Ellis, 1992, Fertility and sterility.

Meiotic progression of mouse oocytes throughout follicle growth and ovulation in vitro.

I. Sargent, D. Barlow, G. Hartshorne, 1994, Human reproduction.

Manipulation of CD98 Expression Affects both Trophoblast Cell Fusion and Amino Acid Transport Activity during Syncytialization of Human Placental BeWo Cells

I. Sargent, C. Boyd, J. Millo, 2003, The Journal of physiology.

Microparticles and immunomodulation in pregnancy and pre-eclampsia.

I. Sargent, C. Redman, 2007, Journal of reproductive immunology.

Immunological disorders of human pregnancy.

I. Sargent, C. Redman, 1986, Oxford reviews of reproductive biology.

Effect of heparin-binding EGF on human preimplantation embryo development

I. Sargent, D. Barlow, K. Martin, 1997 .

Authors' reply

I. Sargent, C. Redman, A. Smarason, 1994 .

Growth rates and antrum formation of mouse ovarian follicles in vitro in response to follicle-stimulating hormone, relaxin, cyclic AMP and hypoxanthine.

I. Sargent, D. Barlow, G. Hartshorne, 1994, Human reproduction.

Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis.

I. Sargent, C. Redman, K. Studená, 1998, American journal of obstetrics and gynecology.

Determination of Fetal RhD Status by Maternal Plasma DNA Analysis

I. Sargent, C. Redman, N. M. Hjelm, 2000, Annals of the New York Academy of Sciences.

Regulation of MHC class I gene expression is at transcriptional and post-transcriptional level in bovine placenta.

I. Sargent, B. Charleston, S. Ellis, 1998, Journal of reproductive immunology.

Cardiovascular Risk Factors in Children and Young Adults Born to Preeclamptic Pregnancies : A Systematic

Y. Kenworthy, A. Wilkinson, I. Sargent, 2012 .

Differential expression profile of microRNAs in human placentas from preeclamptic pregnancies vs normal pregnancies.

T. Han, I. Sargent, Yuan-Qing Yao, 2009, American journal of obstetrics and gynecology.

Microvesicles and pre-eclampsia.

I. Sargent, 2013, Pregnancy Hypertension.

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

Paul J. Harrison, A. Harris, D. Ferguson, 2011, Nanomedicine : nanotechnology, biology, and medicine.

Heparin-binding epidermal growth factor and its receptor ErbB4 mediate implantation of the human blastocyst

J. Heath, I. Sargent, D. Barlow, 2002, Mechanisms of Development.